`
`UNI'l‘LZD S'I‘ATES PA‘I‘EN'I‘ AND TRADEMARK OFFICE
`
`I 'NI‘I'I'ID STA'I'ES DEPARTMENT OF (“OHM [CRCE
`l nltcd Slates Patent and Trademark. 0111m-
`mhme: COMMISSIONER FOR PATENTS.
`l’ [I lice: i431]
`.Mcanudim. Virginia 331.1445“
`.m-p-n-Jlsptn gm-
`
` Al’l’l alt‘A‘l‘ION NI 5MBT‘LR PA'I‘l-JN'I’ .\'I iMltER G R( I! ‘l’ ART ['Nl'l' RI iQI 7] 53'!' l I)
`LUIS-4.932
`‘Jtatl-‘l‘Jt II
`167]
`“12650
`
`
`
`
`
`
`
`PAIR Correspondence Addresswa Address Change
`
`The following fields have been changed to Customer Number 166905 on Ola/038030 via Private PAIR in View
`
`of the certification copied below that authorized the change.
`
`* Con‘e5pondence Address
`
`The addreas for Customer Number 166905 is:
`166905
`
`Foley & LardnerIJP
`3000 K Street NW.
`Suite 600
`
`Washington, DC QUINN-5109
`
`I certify, in accordance with .37 CFR 1.4(d)(4_) that I am:
`
`An attorney or Agent of Record registered to practice before the Patent and Trademark Office who has been given
`power of attorney in this application
`
`_snephew Mamas mammal-men
`
`Stephen B Maebiusx
`
`Liquidia - Exhibit 1006 - Page 1
`
`Liquidia - Exhibit 1006 - Page 1
`
`

`

`UNITED STATES PATENT AND TRADEMARK OFFICE
`
`CERTIFICATE OF CORRECTION
`
`PATENT NO.
`APPLICATION NO.
`l)A'l'liD
`lNVIEN'l‘ORtS]
`
`lJLISULLQIII B?
`'
`: 14;“754932
`2 March 23. 20] I"
`: Ilitcsh Balm Ill :11.
`
`Page ] OFI
`
`It is cenlfied that error appears in the above-identified patent and that said Letters Patent is hereby corrected as shown below:
`
`In the Claims
`
`Column 1?, Claim I, Line 27. “(c1 containing the“ should be —(c] contacting the“.
`
`Signed and Sealed this
`
`Sixteenth Day of May, 2017
`
`Wmflzig.
`
`lace
`Mic-hello K.
`fink-mm ofmv I-rmca' Stan's Imam and h‘rrdmum‘k wim-
`
`Liquidia - Exhibit 1006 - Page 2
`
`Liquidia - Exhibit 1006 - Page 2
`
`

`

`Atty. om. No: 080613-1550
`
`IN THE UNITED STA TES PA TENTAND TRADEAIARK OFFICE
`
`First Inventor Name:
`
`Hitesh BATRA
`
`Tillc:
`
`AN IMPROVED PROCESS TO PREPARE
`TREPROSTINIL. TI-[E ACTIVE INGREDIENT IN
`REMODULTN®
`
`Patent. No.:
`
`9,604,901
`
`Issue Date:
`
`31’282’2017
`
`Examiner:
`
`Yevgeny Valenrod
`
`Art Unit:
`
`1672
`
`Confirmation Number:
`
`1865
`
`REQUEST FOR CERTIFICATE OF CORRECTION FOR
`PTO MISTAKE PURSUANT TO 3? C.F‘.R. § 1.3221511
`
`Commissioner for Patients
`
`PO. Box 1450
`Alexandria. VA 22313-1450
`
`Commissioner:
`
`Enclosed, is a Certificate of Correction, Form PTO-1050, for United States Patent
`
`Number 9.604.901 issued March 28, 2017. The following Patent Office printing error appears in
`
`[he issued patent:
`
`IN THE CLAIMS
`
`The exact claim and line number where the error in the issued patent is showu correctly in
`
`the applicalion file is
`
`Col. 17, claim 1: line 27, *‘(c) comaining the" should be --(c) contacting lhe--.
`
`4823-3353-28 103.1
`
`Liquidia - Exhibit 1006 - Page 3
`
`Liquidia - Exhibit 1006 - Page 3
`
`

`

`Atty. Dkt. No. 080618-1550
`
`Applicant submits that the above change would not constitute new matter, and correction
`
`thereof would not require reexamination.
`
`Pursuant to 37 C.F.R. §1.322, Applicant requests that the enclosed Certificate of
`
`Correction be approved.
`
`Although Applicant believes that no fee is required For this Request, the Commissioner is
`
`hereby authorized to charge any additional fees which may be required for this Request to
`
`Deposit Account No. 19-0741.
`
`Respectfully submitted,
`
`Date
`
` APR 1 1 ZDl
`
`7
`
`FOLEY & LARDNER LLP
`Customer Number: 22428
`Telephone:
`(202) 672-5569
`Facsimile:
`(202) Gil-5399
`
`Stephen B. Maebius
`Attorney for Applicant
`Registration No. 35,264
`
`4323- 5353-28 Hi. 1
`
`Liquidia - Exhibit 1006 - Page 4
`
`Liquidia - Exhibit 1006 - Page 4
`
`

`

`MDDiFIED PTOISBMd (04-05]
`Approved for use through 04:30:200? DMB 0551-0033
`US. Patent and Trademark Bruce; US. DEPARTMENT OF COMMERCE
`Under the Paperwork Reduction no: or 1995‘ no persons are required to respond lo a collection of information unless it displays a valid OMB control number.
`Also Form PTO-1050
`
`UNITED STATES PATENT AND TRADEMARK OFFICE
`
`CERTIFICATE OF CORRECTION
`
`PATENT NO
`
`9,604,901
`
`APPLICATION NO.
`
`144754932
`
`DATED
`
`3r28f2017
`
`Col. 1?. claim 1. line 27. "(c) containing the" should be -~(c) contacting the—.
`
`INVENTOR(S)
`
`Hitesh BATRA; Sudersan M. TULADHAR; Raju PENMASTA; David A.
`WALSH
`
`It is certified that an error appears or errors appear in the above-identified petentand that said Letters
`Patent is hereby corrected as show below:
`
`MAILING ADDRESS OF SENDER {Please do not use customer number below}:
`
`Foley it Lardner LLP
`3000 K Street, N.W.. Suite 600
`Washington DC. 20007-5109
`This collection of information is required by 3? CFR 1.322. 1.323. and 1.324. The i'i-ilormallori is required to obtain or retain a benefit by the public which
`is to rile {and by the USPTD to process: an applicalion. Confidentiality Is governed by .35 USS. 122 and 3? CFR 1.14. This collection is estimated to
`take 1 0 hour to complete. including gathering preparing, and submilling Ihe completed application form to the USPTO Time wilt vary depending upon
`the individual case. Any comments on the amount of time you require to complete this form auditor suggestions For reducing this burden, should be senl
`lo the Chief lnlorrnalion Officer.
`Us. Patent and Trademark Drflce. US. Depenmenl of Commerce. PD. Boar 1450‘ Alexandria, VA 22313-1450 DO NOT SEND FEES OR
`COMPLETED FORMS TO THIS ADDRESS. SEND TO: Attention Certificate of Corrections Branch, Commissioner tor
`Patents. PD. Box 1450. Alexandria, WI 22313-1450
`if you need assistance in completing ilie form, cell l-BOO—PTO-QTQQ and select option 2.
`
`431292620514 1
`
`Liquidia - Exhibit 1006 - Page 5
`
`Liquidia - Exhibit 1006 - Page 5
`
`

`

`Electronic Acknowledgement Receipt
`
`“—
`
`International Application Number:
`
`
`Confirmation Number:
`
`1865
`
`Title of Invention:
`
`PROCESS TD PREPARE TREPROSTINIL. THE ACTIVE INGREDIENT IN
`REMODULIN2
`
`
`
`First Named Inventormpplicant Name:
`
`“—
`
`
`
`Filing Date: 30-JUN-2015
`
`Time Stamp:
`
`13:22:39
`
`Application Type:
`
`Utility under35 USC 11 ‘Iiai
`
`Payment information:
`
`Submitted with Payment
`
`
`
`Document
`
`.
`
`.
`
`File SizelBytesl!
`
`Multi
`
`Pages
`
`Requal for Certificate of Correction
`
`ReqCOdef
`
`.Iu'qii'lfiz|11“.:lTrfilIifiJfifiiluiIHQDifiI-r
`I nafl'
`
`3
`
`Liquidia - Exhibit 1006 - Page 6
`
`Liquidia - Exhibit 1006 - Page 6
`
`

`

`Information:
`
`This Acknowledgement Receipt evidences receipt on the noted date by the USPTO of the indicated documents,
`characterized by the applicant. and inciuding page counts, where applicable. It serves as evidence of receipt similar to a
`Post Card, as described in MPEP 503.
`
`New Applications Under 35 U.S.C. 1 1 1
`If a new application is being filed and the application includes the necessary components for a filing date {see 37 CFR
`1.53ibi-ldi and MPEP 506}, a Filing Receipt [37 CFR 1.54} will be issued in due course and the date shown on this
`Acknowledgement Receipt will establish the filing date of the application.
`
`National Stage of an International Application under 35 U.S.C. 371
`If a timely submission to enter the national stage of an international application is compliant with the conditions of 35
`U.S.C. 371 and other applicable requirements a Form PCTIDOIEOISDOB indicating acceptance of the application as a
`national stage submission under 35 U.S.C. 371 will be issued in addition to the Filing Receipt, in due course.
`
`New International Application Filed with the USPTO as a Receiving Office
`If a new international application is being filed and the international application includes the necessary components for
`an international filing date [see PCT Article 11 and MPEP 1810), a Notification of the International Application Number
`and ofthe International Filing Date {Form PCTIRDHOS} will be issued in due course, subject to prescriptions concerning
`national security, and the date shown on this Acknowledgement Receipt will establish the international filing date of
`the application.
`
`Liquidia - Exhibit 1006 - Page 7
`
`Liquidia - Exhibit 1006 - Page 7
`
`

`

`UNI‘I‘lil) S'rA'riss PA rmr AND TRAIN-{MARK Omen
`
`
`
`UNITED STATI‘E DEPARTMENT OF COMMERCE
`Fain-d Stnlcs Patent and Trademark Oll‘ict‘
`Iridium; CUMWISS lQNEK I‘OR PATENTS
`PD Hal |45II
`Alexandria. Virgmia .115 lJ-Hitl
`n n'u'Msptogui
`
`APPUCATth-l NU.
`ISSUE UA'I'IL
`PATHS—i NU,
`ATI'UKNE‘Y JJUCKI'i'l' NO.
`(.‘(IN'HILVIATIUN NU.
`
`liter—354.033
`UNISEX” 7"
`900490]
`030615-1550
`1305
`
`12425
`
`‘rfilm
`
`will ”till: I 'i‘
`
`Foley ‘5‘: Lardner LLP
`3000 K S'I'Rlili’l‘ NW.
`SUITE 600
`WASHINGTON, DC 20007—5109
`
`The projected patent number and issue date are specified above.
`
`ISSUE NOTIFICATION
`
`Determination of Patent Tenn Adjustment under 35 U.S.C. 154 (b)
`(application filed on or after May 29, 2000}
`
`The Patent Term Adjustment is 0 dayts). Any patent to issue from the. above—identified application will include
`an indication of the adjustment on the front page.
`
`If :1 Continued Prosecution Application (CPA) was filed in the. above-identified application. the filing date. that
`determines Patent Term Adjustment is the filing date of the most recent CPA.
`
`Applicant will. be able to obtain more detailed infonnation by accessing the Patent Application Information
`Retrieval (PAIR) WEB site (http:#pair.uspto.gov).
`
`Any questions regarding the Patent Term Extension or Adjustment determination should be dinected to the
`Office of Patent Legal Administration at (571)-272-7702. Questions relating to issue and publication fee
`payments should be directed to the Application Assistance Unit [AAU] of the Office of Data Management
`[ODMJ at (571)—272—4200.
`
`APPLICANTlSl [Please see PAIR Willi silc It!Iptt'fpnirJIsptogov l'nrndtlilinnal applicants):
`
`Ilitcsh Batru. l'Icrndon. VA;
`United Therapeutics Corporation. Silver Spring. MD:
`Sudcrsan M. Tuladllar. Silver Spling, MD;
`Ruju Penmustn, Ilemdon. VA:
`David A. Walsh, Pahnym. VA:
`
`The United States represents the. largest, most dynamic marketplace in the world and is an unparalleled location
`for business investment, innovation. and commercialization of new technologies. The USA offers tremendous
`resources and advantages for those who invest and manufacture goods here. Through SelectUSA. Our nation
`works to encourage and facilitate business investment. To learn mom about why the USA is the best country in
`the world to develop technology, manufacture products, and grow your business, visit Selectflfifiggv.
`
`TRIO} rRev.
`
`lUftl‘J}
`
`Liquidia - Exhibit 1006 - Page 8
`
`Liquidia - Exhibit 1006 - Page 8
`
`

`

`
`
`UNITED STATES PA’lTjN’I' AND TRADEMARK 01:1:th
`
`I‘NTI‘I'ID STATES DEI‘AR'IMENT 0F CIMIMERI‘E
`l-nited States Patent and Trademark Offici-
`Addams: {fcimxttssit'mtfi l-UR PA rFNI :3
`FE} Ben i450
`mum-hi4. Vngiluil 1231 i- I 5"}
`www 05pm. gov
`
`NOTICE OF ALLOWANCE AND FEE( S) DUE
`
`we
`2242:;
`l-I'oley & Lardner LLP
`3000 K STREET N.W.
`
`to: | 4:20 1 1
`
`WASHINGTON. DC 200075109
`
`N .:
`'.
`”CM“ I R
`van-Anon. ”(131th
`
`1672
`
`DA'I'F. MAILED: 02.?! It'll)”
`
`APPLICATION NO.
`FILING DATE.
`FIRST NAMED Iii-WE. ‘TOR
`.‘\'l'I‘OR.‘\EliY DOCKET NO.
`(IOB'FJRNMTION NO.
`
`HITS-L933
`(16:30.13)! 5
`Ililesh Batm
`080618-1550
`1865
`Il'l'l.l'_.l'll'- INVI‘N I‘ION: PROCESS I'O I'REI‘ARI'L- T'RILPROS'I'INIL. 'l‘lll‘. Al‘l‘lVTi |F\'tiR|i[l|[-.N']' [N RIEMODl'lINl
`
`APPLY. 'J'YPl'.
`I'EN'ITI'Y STATUS
`JSST‘I‘. Hili D' '1".
`PT-"BIJI‘A'TIUN Fliii [)1 IF.
`FRI-TV. PAID 1551' ii". Flili
`TO | A1. Flilit'i! UT 31.“:
`DATE Utfl-‘i
`
`rtonprovisionnl
`I‘NDISCOUN'JI‘LD
`$960
`50
`$960
`5960
`05.“ 1mm ".I'
`
`THE APPLICATION IDENTIFIED ABOVE HAS BEEN EXAMINED AND IS ALLOWED FOR ISSUANCE AS A PATENT.
`
`PR SECU'I‘IO ON THE MERITS IS CI.
`"ED. THIS NOTICE OF ALLOWANCE IS NOT A GRANT OF PATENT RIGHTS.
`TIIIS APPLICATION IS SUBJECT TO WITIIDRAWAI. FROM ISSUE AT THE INITIA'I‘IVI‘I OF THE OFFICE OR UPON
`PETITION BY THE APPLICANT. SEE .37 CFR 1.313 AND MPEP1308.
`
`THE ISSUE FEE AND PUBLICATION FEE. {IF REQUIRED] MUST BE PAID WITIIIN THREE. MONTHS FROM THE
`MAILING DATE OF THIS NOTICE OR THIS APPLICATION SIIALL BE REGARDED AS ABANDONED.
`THIS
`"
`'
`l
`’
`r
`‘
`’
`"
`"
`‘
`'
`i
`.
`SEE 35 U.S.(.‘.. 151. THE ISSUE FEE DUE INDICATED ABOVE DOES
`
`NOT REFLECT A CREDIT FOR ANY PREVIOUSLY PAID ISSUE FEE IN THIS APPLICATION.
`IF AN ISSUE FEE. I-IAS
`PREVIOUSLY BEEN PAID IN TIIIS APPLICATION {AS SHOWN ABOVE). THE RETURN OF PART B OF TIIIS FORM
`WILL BE CONSIDERED A REQUEST TO REAPPLY TI-IE PREVIOUSLY PAID ISSUE FEE TOWARD TIIE ISSUE FEE NOW
`DUE.
`
`HOW TO REPLY TO THIS NOTICE:
`
`1. Review the liNTl'l‘Y STATUS shown above. [1‘ the HN'I'I'I'Y S'I'A’I‘US is. shown as SMALL or M ICRO. verify whether entitlement to that
`entity slams still applies.
`
`II the liN’l‘l'l'Y S'I'ATUS is the same as shown ethove1 pay the ‘l‘OTAl . FEMS} DUE shown zlboVe.
`
`II the liN'l‘l'l'Y S'I'AAI‘US is changed from that shown above. on PART B - Fl il‘XSl ‘I‘RANSMI'I'I'AL complete section number 5 titled
`"Change in Iinlily Status t'li'ont status indimled above)".
`
`For purposes. of this. notice. small entity fees are ”2 the amount ol’ undiseounted tees. and micro entity fees are 12 the amount of small entity
`fees.
`
`1]. PART B - FEEt'S) TRANS MITI'AL, or its equivalent. must he completed and returned to the United States Patent and Trademark Office
`tUSP’l‘O} with your ISSUE [51315 and PUBLICATION 171513 {if required}. If you are charging the feels) to your deposit account, section "4b"
`of Part B - Feds.) 'l'ransmitlal should he completed and an extra copy of the l'onu should he submitted. lfaul equivalent of Pan 8 is filed, a
`request to reapply a previously paid issue fee must he clearly made. and delays in processing may occur due to the difficulty in recognixing
`the paper as an equivalent of Part B.
`
`Ill. All communications regarding this application must give the application number. Please direct all eonnnunicatinns prior to issuance to
`Mail Stop ISSUE lilili unless advised to the contrary.
`
`IMPORTANT REMINDER: Utility patents issuing on applications filed on or after Dec. 12. 1980 may require payment of
`maintenance Ices. It is patentee's responsibility In ensure timely payment of maintenance. fees when due.
`
`P'l‘OL—RS tRev. tilt] ll
`
`Page 1 ot‘3
`
`Liquidia - Exhibit 1006 - Page 9
`
`Liquidia - Exhibit 1006 - Page 9
`
`

`

`PA RT H - FICEIS) TRANSMI‘I‘TAI.
`
`Cumplete and send this farm, together with applicable feels}, to: Mail Mail Stop ISSUE FEE
`Commissioner for Parents
`P.(). Box 1450
`Alexandria. Virginia 22313-1450
`anttx (571)-273-2835
`
`lNSTRL't‘TlUNS: This i'r-rm should be used for transmitting the iSSUE FEE and l‘L'HLICA'TlON FEE (if required}. Blocks I
`thmugh 5 should he cnmpleled where
`
`up l‘nrlrirlte. All further correspondence including the Patenr, advance order.
`I] nutil'icntinn of maintenance fees wilI he mailed tn the cum-n1 curres wndenee address in;
`in it'illfd Ufllt'fis corrected heluw tar directed tJLhEm'lSt' in Block I. by {at specifying a nettr cm‘respnndence address: :tndfm'
`l‘h} indicating :- selnn'nte " - iIi ADDRESS" for
`
`maintenance lee nutifieutiuns.
`
`t-Lrsrrrn'r‘t'unnrzsrionmxct: nitrnrtrssrxmc: In: Elm-I: ru‘w any than: of erfiml
`
`i590
`2-1428
`_.
`ltolcy 8.: Lardner LLP
`3000 K STRRFT N W
`*‘
`-
`‘
`‘
`‘
`'
`SUITE 600
`
`”mum”?
`
`Sale: A certificate of nwiline can nnly he used [or dumeslic mailings nl’ lite
`l‘eefsi 'I‘ransmrttnl. This certificate cannot be used ior any nthet' accompanying
`apt-rs. Ffillih udditiunnl Paper. such as an assignment or rufmill drawing. must
`have it; own ccrtil'rrate nl‘ mailing or U'rtnsmisrmn.
`Certificate of Mailing or Transmission
`l here-hr ccrlii ' that this Feels) 'l‘ransmillnl is being deposited with the United
`Starter. Pasta] Service wid'r sufficient poslarge lur Irrsl class mail in an envelope
`addressed to the Mail Sic.
`ISSUE Hi address above. or being l'acsimrlc
`transmitted to the. USPTO I‘. T l: 273-3385. on the date. indicated below.
`
`murmurs, m: 20007-51”)
`
`APPHL'A'I‘N3K‘ NI].
`FILING 131‘” [i
`'r iRST NAMiLl‘J lNVEN'l'OR
`A'rmnxln' JFK'Kh'T ND.
`(Tl-INFlKWATifi-N NI"!
`
`HHS-[932
`ONJWZOIS
`[[ilesh Batrn
`0806i ti- i550
`1365
`THU; 01" lNVIiNl'lON: PROCESS 1'0 PREPARE 'I‘Rlil‘ROS'l'INIL. 'I'llI'. ACTIVE INGREDIENT [N REMODULINZ
`
`DATEDUT
`TO'I'AT. FEELS: DL’E
` PREV. PAID ISSUE FE:
`[‘1 "BLICATIDN FEE DUE.
`IESL‘E FEE II" 7F.
`ENTITY STAPLES
`'l'Y'P'E
`.I’LF'PLV.
`
`
`rinnpmvisiunal
`I'NDISCD‘I 'N'Tl in
`$960
`50
`‘59th
`89:30
`05!] Silt)! ".I'
`
`I'DCAMIN'ER
`ART T ‘51"!
`FLAS'SASI "BUASS
`
`VALENROD. YE VG‘liNY
`[ti—U
`562 466000
`
`1. Change of eum‘trpnndence address nr indication nl"’Fee Address" [37
`C138 I563}.
`
`1. Fur printing UI'I lire pnlenl l‘rtnrl. page. list
`{I} The names of up tn 3 registered patent ath‘nrneys
`or agents OR. ultemalively.
`‘e ui'corrcspttndencc address for Change of Correspondence
`CI (Thu
`Address unit PTOiSlir'llZi :rllarched.
`{2) The name of a single firm {having ilS a member a
`Cl "Fee Address“ indication tni' "Fee Address" Indication form
`registered attorney at agent: rrnd the names. ef up Lt!
`2 registered patent attorneys ur :tgcnts. ll I'lu mime is
`H1‘U!5lii4?t Rev 03-01 or more rcccnli attached. ('5: of a Cuslumer
`listed. nu name will he printed.
`Number is required.
`3. ASSIGNEE- NAME AND RESIDENCE DATA TO [113 PRINTED ON THE PATENT [print .11' typel
`if an :rssignee is identified below. the document hits been filed for
`PLEASE NO'I'E: [‘nlesr an assignee is idenlified below. rm :rssigncc data will appear till the patent.
`rccurdatit'rn :15 wt lisrth in 3‘." ('FR 3.] |. Completing: oi" this firm is NUT a substitute fnr tiling an assignment.
`Ml NAME OI‘ ASS IGNIEIE
`liil RPS l BENCH: it‘lT'i' and S'I‘A’I‘E DR (Til 'N'I'RY:
`
`
`
`—
`
`I
`
`1
`'
`
`
`PlCtISL' check the appropriate nssignee category or categories twill not Ix printed on the patent: : D Individual D Corporation or nlher pr'ivrtte grmrp entit}.r D Government
`4:1. The following t‘ccts: are suhmirted:
`4h. Payment nI'Iit-ettt: ll’lease first reapply arr,- previmealy paid issue fee shmrrt culture}
`in Issue l‘ee
`El A check is enclnsed.
`D Publication ['11. I'M: small entity dist-mint ptrmitlcd:
`D Payment by credit card. I‘m-m P101038 is attached.
`CI Advance ()rder . {-l ul't.‘opies
`D'l'he direetur is hereby authorized to charge Ihc required l'eet‘ral. any deficiency. or credits .‘l.t1_\-‘
`overpayment. to Dcpntil Acmunl Number _ fenclnsc an extra copy ol' this Ibrml.
`
`
`5. Change in Emily Status tl'rnm stnltts indicated uhmci
`D Applicant certifying micro entity status. See T." (“FR l.29
`
`NQTIE: Absent .1 valid certification of Micro [intity Stratus tree lam-rt PTOISWISA and 1511:. issue
`tee payment in the micrt'r entity :rmuurrl will not be accepted at the risk of implication abandonment
`
`D Applicanl asserting smnll cntily status. See 3? L‘FR 1.2?
`
`Cl Applicant changing to regular undiscounted fee status.
`
`.3011? Il'tlh‘e application wars previously under micrrrentily status, checking this box will he taken
`In ht: a nntdrcatmn ur loss nl cntltlcmcn! Irv micro cnllly status.
`mm Checking this but; will be taken to be it nolilicntiun of loan ni‘cnlitlement to small or micm
`entity status. as applicable.
`tied in :tcmrtLtnce with 3? CFR 1.31 and 1.33. See 3? (Tl-R 1.4 for signature rec uiremL-nts Lll'id certifications.
`
`
`NOTE: This item musl hc 5i
`
`
`
`.»\uthorized Signature
`
`Date
`
`Typed or printed name
`Regrslratiun Nu.
`
`
`F'I'OL-SS Part B {'10- | 3] Apprm'ed for use drmugh lflflliltlll
`
`0MB 0651-0053
`
`L15. Patent and 'I'rndcmnrk Office: US. DEPARTMENT OI" (‘UMMJ'RC‘E
`
`Page 2 of 3
`
`Liquidia - Exhibit 1006 - Page 10
`
`Liquidia - Exhibit 1006 - Page 10
`
`

`

` --
`
`
`UNITED STATES PA’lEN’I‘ AND TRADEMARK OFFICE
`
`'l.‘-\'T'l‘F.['I STATES lJEI‘AR'l'MENT 0F CUMMEIH‘E
`[-nilcd States Patent and detlll'ark (Erica
`atoms: {TOMMISSH'JNtzR l-UR. PA rFNI s
`no am 1450
`Alumni. Vaginal 22311415!)
`wwu- usptr. guv
`
`CONFIRMNI'ION ND.
`ATI‘CIRNEY DOCKET NO.
`FIRSi' NAMED LVVENTOR
`FILB‘G DATE
`APPLICATION NU.
`
`”mam:
`tWJWELI | 5
`HilL'sh Extra
`(18(th I ii- I 550
`IRISS
`
`mm W.
`
`l-I'oiey & Lardner LLI’
`3000 K STREETNNV.
`S UI'I‘li 600
`WASHINGTON. DC 200076109
`
`vmrfiaon. YEVGIFL-YY
`
`mu 1'NIT
`PAPER NL‘MHI'ER
`
`1672
`
`DATE MAILED: 0211 4(20 l7
`
`Determination of Patent Term Adjustment under 35 U.S.C. 154 {b}
`(Applications filed on or after May 29, 2000)
`
`The Office has discontinued providing a Patent Term Adjustment (PTA) calculation with the Notice of Allowance.
`
`to eliminate the
`lS4tb)(3'_l-(B){i')
`Section l('h'_l(2J of the AIA Technical Corrections Act amended 35 U.S.C.
`requiiement that the Office provide a patent
`term adjustment determination with the notice of allowance. See
`Revisions to Patent Term Adjusnnent. 78 Fed. Reg. 19416, 19417 (Apr.
`11 2013). Therefore. the Office is no longer
`providing an initial patent term adjustment determination with the notice of allowance. The Office will continue to
`provide a patent
`teiTn adjustment determination with the Issue Notification Letter that
`is mailed to applicant
`approximately three weeks prior to the issue date of the patent. and will include the patent term adjustment on the
`patent. Any request for reconsideration of the patent term adjustment determination (or reinstatement of patent term
`adjustment) should follow the process outlined in 37 CFR 1.705.
`
`Any questions regarding the Patent Term Extension or Adjustment determination should be directed to the Office of
`Patent Legal Administration at (571)—272—7702. Questions relating to issue and publication fee payments should be
`directed to the Customer Service Center of the Office of Patent Publication at l-t888i-i86-0101 or (571)-272—4200.
`
`NHL—85 tRev. tilt] I]
`
`’agc 3 of 3
`
`Liquidia - Exhibit 1006 - Page 11
`
`Liquidia - Exhibit 1006 - Page 11
`
`

`

`OMB Clearance and PFtA Burden Statement for PTOL-BS Part B
`
`The Paperwork Reduction Act lI’RA) of 1995 requires Federal agencies to obtain Office of Management and
`Budget approval before requesting ntost types of information front the public. When OMB approves an agency
`request to collect information front the public, 0MB (i) provides a valid OMB Control Number and expiration
`date for the agency to display on the instrument tltat will be used to collect lite information and (ii) requires the
`agency to inform the public abOut the OMB Control Numher‘s legal significance in accordance with 5 CFR
`1320.5lh).
`
`The information collected by P'fOl--85 Pan B is required by 37 CF'R 1.31 l. The information is required to obtaitt
`or retain a benefit by the public which is to file (and by the U S P'I'O to process) an application. Confidentiality is
`governed by 35 USE. 122 and 3? CFR 1.1-1. This Collection is estimated to take 12 minutes to complete,
`including gathering. preparing. and submitting the completed application form to tlte USI’TO. Time will vary
`depending upon the individual case. Any comments on tlte amount of time you require to complete this form
`andfor suggestions for reducing this burden, should be scttt
`to the Chief Information Officer, LLS. Patent and
`Tradctttark Office, US. Department of Cotttmcrcc. PD. Box 1450, Alexandria, Virginia 22313—1450. DO NOT
`SEND l-‘IinS 0R COMPLETED FORMS TO THIS ADDRESS. SEND TO: Commissioner for Patents. 13.0. Box
`
`1450. Alexandria, Virginia 22313-1450. Under the Paperwork Reduction Act of 1995. no persons are required to
`respond to a collection of information unless it displays a valid OMB control number.
`
`Privacy Act Statement
`
`The Privacy Ael of 1974 (P.L. 93-579) requires tltat you be given certain information in connection with your
`submission of the attached form related to a patent application or patent. Accordingly, pursuant
`to the
`requirements of the Act, please be advised that: {1) the general authority for the collection of this information is
`35 U.S.(_‘.. 2tb11212 (2) fumishing of tlte infortmttion solicited is voluntary; attd t3) the principal purpose for which
`the information is used by the [1.5. Patent attd Trademark Office is to process and/or examine your submission
`related to a patent application or patent. If you do ttot
`l‘untish the requested information, the LLS. Patent and
`Trademark Office may not be able to process andt'or examine your submission, which may result in termination of
`proceedings or abandonment of the application or expiration of the patent.
`
`‘lhc information provided by you in this form will be subiect to the following routine uses:
`1. The information on this form will be treated confidentially to the extent allowed under tltc 1"rccdont of
`Information Act [5 11.811 552] and tlte Privacy Act (5 1|.S.C 552:1). Records from tltis system of records
`may be disclosed to the Department of Justice to determine whether disclosure of tltese records is required
`by the Freedom of lttforntatiott Act.
`2. A record from this system of records ntay be disclosed. as a routitte use, in the course of presenting evidence
`to a court. magistrate. or administrative tribunal. including disclosures to opposing counsel in the course of
`settlement negotiations.
`3. A record itt this system of records may be disclosed, as a routine use, to a Member of Congress submitting a
`request involving an individual, to whom the record pertains, when the individual has requested assistance
`frotn the Member with respect to the subject tiiatter of the record.
`4. A record in this system of records may be disclosed. as a routine use. to a contractor of the Agency having
`need for the information in order to perform a contract. Recipients of information shall be required to
`comply with the requirements of the Privacy Act of 1974. as amended. pursuant to 5 U.S.(.‘.. 552attn}.
`5. A record related to an International Application filed under the Patent Cooperation Treaty in this system of
`records may be disclosed, as a routine use, to the International Bureau of the World Intellectual Property
`Organization, pursuant to the Patent Cooperation Treaty.
`6. A record in this system of records may be disclosed. as a routine ttsc, to another federal agency for purposes
`of National Security review {35 USE. 181) and for review pursuant to the Atomic Energy Act (42 11.3.(1
`218tc)).
`7'. A record from this system of records may be disclosed, as a routine use, to the Administrator. General
`Services, or hislher designee. during an inspection of records conducted by GSA as part of that agency's
`responsibility to recommend improvements in records management practices and programs, under authority
`of 44 ll.S.C. 2904 attd 2906. Such disclosure sltall be made in accordance with the GSA regulations
`governing inspection of records for this purpose, and any other relevant [i.e.. GSA or Cotttmercet directive.
`Such disclosure shall not he used to make determinations about individuals-
`
`8. A record from this system of records may be disclosed. as a routine use, to the public after either publication
`of the application pursuant to 35 U.S.C. 12201) or issuance of a patent pursuant to 35 Ll.S.C. [5 1. Further, a
`record may be disclosed. subject to the limitations of 37 (.‘l’R 1.14, as a routine use, to tltc public if the
`record was filed iii an application which became abandoned or itt which the proceedings were terminated
`and which application is referenced by either a published application. an application open to public
`inspection or an issued patent.
`9. A record from this system of records may be disclosed, as a routine use. to a Federal. State. or local law
`enforcement agency. if the 1181’1‘0 becomes aware of a violation or potential violation of law or regulation.
`
`Liquidia - Exhibit 1006 - Page 12
`
`Liquidia - Exhibit 1006 - Page 12
`
`

`

`
`
`No
`
`Application No.
`14i?54.932
`
`$33313; VALEN noo
`
`Applicantls)
`BATRA ET AL.
`
`$2.32“ "‘“m‘” "’ Fi'”
`
`Notice of Allowabitity
`
`-- The MAILING DATE of this communication appears on the cover sheet with the correspondence address--
`All claims being allowable. PROSECUTION ON THE MERITS IS (OFI REMAINS} CLOSED in this application.
`It not included
`herewith (or previously mailed}. a Notice of Allowance (PTOL-Bfi) or other appropriate communication will be mailed in due course. THIS
`NOTICE OF ALLOWABILITY IS NOT A GRANT OF PATENT RIGHTS. This application is subject to withdrawal from issue at the initiative
`of the Office or upon petition by the applicant. See 37 CFR 1.313 and MPEP 1308.
`
`1._ [I This communication is responsive to HCE filed on 12/21/1'5.
`
`I] A declarationlsyalfidayitts) under 37 CFR 1.130(b} Wasr‘Were tiled on
`
`2. [I An election was made by the applicant in response to a restriction requirement set forth during the interview on
`requirement and election have been incorporated into this action.
`
`The allowed claimis} isiare i‘ 6 and 8-14. As a resultoi the allowad claimtsj. you may be eligible to benefit from the Patent
`Prosecution Highway program at a participating intellectual property office for the corresponding application. For more information.
`please see http:iiwwwusptc.goyipatentsiinit_eventsipphiindeir.jsp or send an inquiry to PPHteedback©uspto.goy.
`
`: the restriction
`
`3.
`
`4. El Acknowledgment is made of a claim for foreign priority under 35 U.S.C. § I 19(a)-{d) or If].
`Certified copies:
`'c) [I None of the:
`a) [I All
`b] [I Some
`1. I] Certified copies of the priority documents have been received.
`2. El Certified copies of the priority documents have been received in Application No. _
`3. D Copies of the certified copies of the priority documents have been received in this national stage application lrom the
`International Bureau (PCT Fiule 17.2(an.
`’ Certified copies not received:_
`
`Applicant has THREE MONTHS FROM THE ”MAILING DATE“ of this communication to file a reply complying with the requirements
`noted below. Failure to timely comply will result in ABANDONMENT of this application.
`THIS THREE-MONTH PERIOD IS NOT EXTENDABLE.
`
`5. El CORRECTED DRAWINGS ( as "replacement sheets“) must be submitted.
`
`El
`
`including changes required by the attached Examiner’s Amendment i Comment or in the Office action of
`Paper NoJMail Date _.
`Identifying indicia such as the application number {see 3? CFR 1.84(c)) should be written on the drawings in the Iron! {not the back) of
`each sheet. Replacement sheel{s] should be labeled as such in the header according to 3? CFR 1.121 (d).
`
`6. I] DEPOSIT OF andior iNFORMATION about the deposit of BIOLOGICAL MATERIAL must be submitted. Note the
`attached Examiner's comment regarding REQUIREMENT FOR THE DEPOSIT OF BIOLOGICAL MATERIAL
`
`Primary Examiner. Art Unit 1672
`
`Attachmentls)
`1. E] Notice of References Cited {PTO-892}
`
`2. E Information Disclosure Statements (PTOiSBiOB).
`Paper Nc,iMaiI Date
`3. E] Examiner's Comment Regarding Requirement for Deposit
`of Biological Material
`4. El Interview Summary {PTO-413).
`Paper NoJMaiI Date
`iYEVGENY VALENFtODi
`
`u E Falenl and Trademark Oliioe
`PTOL-S? (Rev. 08-13)
`20170209
`
`5. [:1 Examiners AmendmenUCcmment
`
`6. El Examiners Statement of Reasons for Allowance
`
`7 [Z] Other
`
`.
`
`Notice oi Allowability
`
`Part of Paper Neill/la“ Date
`
`Liquidia - Exhibit 1006 - Page 13
`
`Liquidia - Exhibit 1006 - Page 13
`
`

`

`
`
`ApplicationIControl No.
`
`AppllcanttsyPatent Under
`Reexamination
`
`Search Notes
`
`14754932
`
`BATRA ET AL.
`
`
`
`
`
`EXBITIIIIEI'
`
`A" Unit
`
`YEVEGENY VALENFIOD
`
`18?2
`
`
`
`
`
`
`CPC- SEARCHED
`
`
`
`“mm:-
`
`
`
`21912017
`0070 59172; 51 {08; 511'41; 51/412; 213x08; 4052’0075
`
`
`
`
`
`
`
`CPC COMBINATION SETS - SEARCHED
`
`
`
`US CLASSIFICATION SEARCHED
`
`
`_ama_—-m
`_ 21912017
`
`
`
`
`
`
`
` SEARCH NOTES
`
`
`
`
`
`Examiner
`Search Notes
`
`EAST
`219/2017
`
`
`
`
`Inventor
`2191201 7
`YV
`
`
`991201 7
`YV
`
`
`
`007C 59U2; 51108; 51341; 51/412; 213108; 40510075
`
`
`
`
`
`INTERFERENCE SEARCH
`
`
`
`
`
`
`US Class!
`CPO Symbol
`
`W
`21912017
`5972: 51108; 51141; 511412213108: 40510075
`007C
`
`
`562 W 466 21912017
`
`
`
`Date
`
`Examiner
`
`U5 Subclass I CPC Group
`
`
`
`r’Vr’Eh-‘EOZSEINIV‘ VALENRODJ
`Primary ExaminerArt Unit 16??
`
`
`
`U 3 Patent and Trademark Oifim
`
`arm of Paper No
`
`2090209
`
`Liquidia - Exhibit 1006 - Page 14
`
`Liquidia - Exhibit 1006 - Page 14
`
`

`

`Receipt date: 12/21/2016
`
`14754932 - GAU: 1672
`
`Atty. Dkt. No. 030618-1550
`
`IN THE UNITED STATES PA TENTAND TRADEMARK OFFICE
`
`First Inventor Name:
`
`Hitesh BATRA
`
`Title:
`
`AN IMPROVED PROCESS TO PREPARE
`TREPROSTINIL, THE ACTIVE INGREDIENT IN
`REMODULINCRE
`
`Application No.1
`
`143’754932
`
`Filing Date:
`
`6H30i’20] 5
`
`Examiner:
`
`Yeygeny Valenrod
`
`Art Unit:
`
`1672
`
`Confirmation No.:
`
`ISISS
`
`INFORMATION DISCLOSURE STATEMENT
`UNDER 37 CFR 1.56
`
`Mail Stop RCE
`Commissioner for Patents
`P.O. Box I450
`
`Alexandria, VA 223 I 3-1 450
`
`Commissioner:
`
`Applicant submits herewith documents for the Examiner’s consideration in accordance
`
`with 3? CFR _§§1.56, 1,9? and 1.98.
`
`Applicant respectfully requests that each listed document be considered by the Examiner
`
`and be made of record in the present application and that an initialed copy of Form PTOKSBIOB
`
`be returned in accordance with MPEP §609.
`
`The submission of any document herewith is not an admission that such document
`
`constitutes prior art against the claims of the present application or that such document is
`
`considered material to patentability as defined in 37 CFR §1.56(b). Applicants do not waive any
`
`rights to take any action which would be appropriate to antedale or otherwise