US009651533B2
`
`(12) United States Patent
`US 9,651,533 B2
`Islarn
`(45) Date of Patent:
`*May 16, 2017
`
`(10) Patent No.:
`
`(54)
`
`(71)
`
`(72)
`
`SHORT-WAVE INFRARED
`SUPER-CONTINUUM LASERS FOR
`DETECTING COUNTERFEIT OR ILLICIT
`DRUGS AND PHARMACEUTICAL PROCESS
`CONTROL
`
`Applicant: OMNI MEDSCI, INC., Ann Arbor, MI
`(US)
`
`Inventor:
`
`Mohammed N. Islam, Ann Arbor, MI
`(US)
`
`(58) Field of Classification Search
`CPC ....... G01N 33/15; G01N 21/359; G01N 33/49
`(Continued)
`
`(56)
`
`References Cited
`U. S. PATENT DOCUMENTS
`
`4,063,106 A
`4,158,750 A
`
`12/1977 Ashkin et a1.
`6/1979 Sakoe et a1.
`(Continued)
`
`FOREIGN PATENT DOCUMENTS
`
`(73)
`
`Assignee:
`
`Omni Medsci, Inc., Ann Arbor, MI
`(US)
`
`CN
`DE
`
`101849821 B
`102010012987 A1
`
`7/2013
`10/2010
`
`(*)
`
`Notice:
`
`Subject to any disclaimer, the term of this
`patent is extended or adjusted under 35
`U.S.C. 154(b) by 0 days.
`
`This patent is subject to a terminal dis-
`claimer.
`
`(21)
`
`Appl. No.: 14/875,709
`
`(22)
`
`Filed:
`
`Oct. 6, 2015
`
`(65)
`
`Prior Publication Data
`
`US 2016/0047787 A1
`
`Feb. 18, 2016
`
`Related US. Application Data
`
`(63)
`
`Continuation of application No. 14/108,986, filed on
`Dec. 17, 2013, now Pat. No. 9,164,032.
`(Continued)
`
`Int. Cl.
`
`(51)
`
`G01] 5/20
`G01N 33/15
`
`US. Cl.
`
`(52)
`
`(2006.01)
`(2006.01)
`(Continued)
`
`(Continued)
`
`OTHER PUBLICATIONS
`
`Istepanian, Robert H., “The Comparative Performance of Mobile
`Telemedical Systems based on the IS-54 and GSM Cellular Tele-
`phone Standards”; Journal of Telemedicine and Telecare 1999; pp.
`97-104.
`
`(Continued)
`
`Primary Examiner 7 David Porta
`Assistant Examiner 7 Abra Fein
`
`(74) Attorney, Agent, or Firm 7 Brooks Kushman RC.
`
`(57)
`
`ABSTRACT
`
`A measurement system includes a wearable measurement
`device for measuring one or more physiological parameters,
`including a light source comprising a plurality of light
`emitting diodes (LEDs) configured to generate an output
`optical beam with a near-infrared wavelength between 700
`nanometers and 2500 nanometers. The light source is con-
`figured to increase signal-to-noise ratio by increasing a light
`intensity and pulse rate of the LEDs. The system includes a
`plurality of lenses configured to receive the output optical
`beam and to deliver an analysis output beam to a sample.
`The wearable measurement device includes a receiver con-
`
`CPC ........... G01N 33/15 (2013.01); A6IB 5/0013
`(2013.01); A6IB 5/0022 (2013.01);
`(Continued)
`
`figured to process the analysis output beam reflected or
`transmitted from the sample and to generate an output signal
`(Continued)
`
`1 800
`/
`
`1802
`1804
`CaF
`/
`1801
`\
`
`
`BS
`
`$08
`1806
`
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`CHOPPER
`$03
`POL
`
`
`7 SAMPLE DETECTOR +
`K1805
`
`SCSOURCE + MONOCHROMATOR <
`
`
`SAMPLE
`:0> PRE—AMP (MCT)
`
`
`
`
`1 807
`
`REFERENCE DETECTOR
`+ PRE—AMP (MOT)
`:1 REFERENCE
`1809
`‘— LOCK-IN AMP #1
`
`
`
`
`
`/
`
`2
`
`
`
`
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`COMPUTER
`
`
`
`/1811
`
`<— LOCK-1N AMP #2
`
`
`
`1810
`
`
`
`:0>
`
`Page 1
`
`OMNI 2004 - |PR20-00209
`
`Page 1
`
`OMNI 2004 - IPR20-00209
`
`

`

`US 9,651,533 B2
`
`Page 2
`
`that may be transmitted to a remote device configured to
`process the received output status to generate processed data
`and to store the processed data.
`_
`_
`18 Clalms, 26 Drawmg Sheets
`
`_
`_
`Related U-S- Applicatlon Data
`
`(60) Provisional application No. 61/747,487, filed on Dec.
`31, 2012.
`
`(51)
`
`(200601)
`(2006.01)
`(2006.01)
`(388281)
`(
`~
`)
`(201401)
`(2006.01)
`(200601)
`(200601)
`(200601)
`(2006.01)
`
`Int' 0'
`A613 5/1455
`A613 5/00
`G01] 3/10
`$01; 322183
`G01N 21/359
`A613 5/145
`““33””
`H015 3/30
`G01J3/14
`G01] 3/18
`(52) US. CL
`CPC .......... A613 5/0075 (2013.01); A613 5/0086
`(2013.01); A613 5/0088 (2013.01); A613
`5/1455 (2013.01); A613 5/14532 (2013.01);
`A613 5/14546 (2013.01); A613 5/4547
`(201301); GOIJ3/108 (2013.01); GOIJ3/28
`(2013.01); G01] 3/453 (2013.01); G01N
`21/359 (2013.01); G01N33/49 (2013.01);
`A613 2562/0233 (2013.01); A613 2562/0238
`(2013.01); A613 2562/146 (2013.01); A613
`2576/02 (2013.01); G01] 3/14 (201301);
`G01] 3/1838 (2013.01); G01] 2003/104
`(2013.01); G01] 2003/2826 (2013.01); G01N
`2201/061 (2013.01); G01N 2201/062
`(2013.01); G01N 2201/12 (2013.01); HOIS
`3/302 (2013 01)
`‘
`
`(58) Field Of Classification Search
`USPC ....................................................... 250/3384
`See application file for complete search history.
`.
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`OMNI 2004 - IPR20-00209
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`US 9,651,533 B2
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`OMNI 2004 - IPR20-00209
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