a2) United States Patent
`US 9,861,286 B1
`(0) Patent No.:
`*Jan. 9, 2018
`(45) Date of Patent:
`Islam
`
`US009861286B1
`
`SHORT-WAVE INFRARED
`SUPER-CONTINUUM LASERS FOR EARLY
`DETECTION OF DENTAL CARIES
`
`(56)
`
`References Cited
`U.S. PATENT DOCUMENTS
`
`(54)
`
`(71)
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`(72)
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`(73)
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`Applicant: OMNI MEDSCI, INC., Ann Arbor, MI
`(US)
`
`Inventor: Mohammed N.Islam, Ann Arbor, MI
`(US)
`
`Assignee: Omni Medsci, Inc., Ann Arbor, MI
`(US)
`
`(*)
`
`Notice:
`
`Subject to any disclaimer, the term ofthis
`patent is extended or adjusted under 35
`U.S.C. 154(b) by 0 days.
`
`This patent is subject to a terminal dis-
`claimer.
`
`(21)
`
`Appl. No.: 15/686,198
`
`(22)
`
`Filed:
`
`Aug. 25, 2017
`
`4,063,106 A
`4,158,750 A
`
`12/1977 Ashkin etal.
`6/1979 Sakoeet al.
`(Continued)
`
`FOREIGN PATENT DOCUMENTS
`
`DE
`EP
`
`102010012987 Al
`1148666
`
`10/2010
`10/2001
`
`(Continued)
`
`OTHER PUBLICATIONS
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`Istepanian, Robert H., “The Comparative Performance of Mobile
`Telemedical Systems based on the IS-54 and GSM Cellular Tele-
`phone Standards”; Journal of Telemedicine and Telecare 1999; pp.
`97-104.
`
`(Continued)
`
`Primary Examiner — Tarifur Chowdhury
`Assistant Examiner — Md M Rahman
`
`(74) Attorney, Agent, or Firm — Brooks Kushman P.C.
`
`Related U.S. Application Data
`
`(57)
`
`ABSTRACT
`
`(63)
`
`Continuation of application No. 15/357,136, filed on
`Nov. 21, 2016, now Pat. No. 9,757,040, which is a
`(Continued)
`
`(51)
`
`Int. Cl.
`
`GOLF 3/00
`AG6IB 5/00
`
`(52)
`
`USS. Cl.
`
`(2006.01)
`(2006.01)
`(Continued)
`
`CPC we AG6IB 5/0088 (2013.01); A6IB 5/0013
`(2013.01); A6IB 5/0022 (2013.01);
`(Continued)
`Field of Classification Search
`CPC ...... GO1J 3/02; GO1J 3/28; GO1J 3/42; GOIN
`21/31; GOIN 21/552
`
`(58)
`
`A wearable device for use with a smart phone or tablet
`includes LEDs for measuring physiological parameters by
`modulating the LEDs and generating a near-infrared multi-
`wavelength optical beam. At least one LED emits at a first
`wavelength having a first penetration depth and at least
`another LED emits at a second wavelength having a second
`penetration depth into tissue. The device includes lenses that
`deliver the optical beam to the tissue, which reflectsthe first
`and second wavelengths. A receiver is configured to capture
`light while the LEDs are off and while at least one of the
`LEDs is on and to difference corresponding signals to
`improve a signal-to-noise ratio of the optical beam reflected
`from the tissue. The signal-to-noise ratio is further increased
`by increasing light intensity of at least one of the LEDs. The
`device generates an output signal representing a non-inva-
`sive measurement on blood within the tissue.
`
`(Continued)
`
`20 Claims, 18 Drawing Sheets
`
`saea
`
`CHOPPER
`
`1273
`
`=
`
`
`
`
`
`MONOCHROMATOR |
`AMPLIFIER
`
`we inSb DETECTOR +
`
`
`OUTPUT SLIT
`
`
`PRE-AMP
`
`LOCIGIN
`
`Page 1
`
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`OMNI 2002 - IPR20-00209
`
`

`

`US 9,861,286 B1
`
`Page 2
`
`PPPPPEEEEEEEEPEESEPEPSPEEEPEEPEESPPEEEPEPEErEPrS
`
`Bl
`Bl
`Bl
`Bl
`Bl
`Bl
`Bl
`Bl
`Bl
`Bl
`
`Bl
`
`4,958,910
`4,989,253
`5,078,140
`5,084,880
`5,086,401
`5,134,620
`180378
`5,191,628
`5,218,655
`5,230,023
`oerts)
`5367.256
`5,267,323
`5,300,097
`5,303,148
`asoa
`5323404
`5,345,538
`5,400,165
`oesI)
`3 544684
`5.572.999
`5,617,871
`5,631,758
`eee4e4
`3,606.78
`5,704,351
`5,718,234
`aaatos
`3792204
`5.812.978
`5,855,550
`5,862,803
`oe)
`3944/6590
`5.950.629
`5,957,854
`5,970,457
`anne
`6.115.673
`6,185,535
`6,200,309
`ote
`eaex96
`6.273.858
`6,278,975
`6,281,471
`Ooeeg
`6.301.271
`6,301,273
`6,333,803
`6,337,462
`6,340,806
`6.350.261
`6,364,834
`6.374.006
`Ooeeol
`6407853
`6.436.107
`6441.747
`6442.430
`6443 800
`mets
`6,450,172
`6,453,201
`6,454,705
`6,458,120
`6,462,500
`6,463,361
`
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`OMNI 2002 - IPR20-00209
`
`Related U.S. Application Data
`
`continuation of application No. 14/651,367, filed as
`application No. PCT/US2013/075736 on Dec. 17,
`2013, now Pat. No. 9,500,635.
`Provisional application No. 61/747,477, filed on Dec.
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`
`(60)
`
`(2006.01)
`(2006.01)
`(2006.01)
`(2006.01)
`(2006.01)
`(2014.01)
`(2014.01)
`(2006.01)
`(2006.01)
`(2006.01)
`(2006.01)
`(2006.01)
`(2006.01)
`(2006.01)
`(2006.01)
`(2006.01)
`(2006.01)
`
`(51)
`
`(52)
`
`(56)
`
`Int. Cl.
`GOIN 33/49
`GOIN 33/44
`GOIN 33/15
`GOIN 33/02
`GOIN 21/88
`GOIN 21/3563
`GOIN 21/359
`GOLJ 3/453
`AGIB 5/145
`AGIB 5/1455
`HOIS 3/30
`GOIN 21/39
`GOIM 3/38
`GOLJ 3/28
`GOLJ 3/10
`GOLJ 3/18
`GOL 3/14
`U.S. Cl.
`CPC vee. A61B 5/0075 (2013.01); AGIB 5/0086
`(2013.01); A61B 5/1455 (2013.01); A61B
`5/14532 (2013.01); A61B 5/14546 (2013.01);
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`(2013.01); GO1J 3/28 (2013.01); GOLJ 3/2823
`(2013.01); GOLF 3/453 (2013.01); GOIN
`21/359 (2013.01); GOIN 21/3563 (2013.01);
`GOIN 21/39 (2013.01); GOIN 21/88
`(2013.01); GOIN 33/02 (2013.01); GOIN
`33/15 (2013.01); GOIN 33/442 (2013.01);
`GOIN 33/49 (2013.01); AGIB 2562/0233
`(2013.01); A6IB 2562/0238 (2013.01); A6IB
`2562/146 (2013.01); A61B 2576/02 (2013.01);
`GOLJ 3/14 (2013.01); GOIJ 3/1838 (2013.01);
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`(2013.01); GOIM 3/38 (2013.01); GOIN
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`(2013.01); GOIN 2201/062 (2013.01); GOIN
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`HO1S 3/302 (2013.01)
`(58) Field of Classification Search
`USPC ciccecccccccesetsccesenteceecesseecensssaeecestsseeeeeees 356/300
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`

`US 9,861,286 B1
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