(12) United States Patent
`US 9,757,040 B2
`Islarn
`(45) Date of Patent:
`*Sep. 12, 2017
`
`(10) Patent No.:
`
`US009757040B2
`
`SHORT-WAVE INFRARED
`SUPER-CONTINUUM LASERS FOR EARLY
`DETECTION OF DENTAL CARIES
`
`(56)
`
`References Cited
`U. S. PATENT DOCUMENTS
`
`(54)
`
`(71)
`
`(72)
`
`Applicant: OMNI MEDSCI, INC., Ann Arbor, MI
`(US)
`
`Inventor: Mohammed N. Islam, Ann Arbor, MI
`(US)
`
`(73)
`
`Assignee: Omni Medsci, Inc., Ann Arbor
`
`(*)
`
`Notice:
`
`Subject to any disclaimer, the term of this
`patent is extended or adjusted under 35
`U.S.C. 154(b) by 0 days.
`
`This patent is subject to a terminal dis-
`claimer.
`
`(21)
`
`Appl. No.: 15/357,136
`
`(22)
`
`Filed:
`
`Nov. 21, 2016
`
`(65)
`
`(63)
`
`Prior Publication Data
`
`US 2017/0071474 A1
`
`Mar. 16, 2017
`
`Related US. Application Data
`
`Continuation of application No. 14/651,367, filed as
`application No. PCT/US2013/075736 on Dec. 17,
`2013, now Pat. No. 9,500,635.
`(Continued)
`
`Int. Cl.
`
`(51)
`
`G01] 3/00
`A613 5/00
`
`US. Cl.
`
`(52)
`
`(2006.01)
`(2006.01)
`(Continued)
`
`CPC .......... A613 5/0088 (2013.01); A613 5/0013
`(2013.01); A613 5/0022 (2013.01);
`(Continued)
`Field of Classification Search
`CPC ...... G01] 3/02; G01] 3/28; G01] 3/42; G01N
`21/31
`
`(58)
`
`4,063,106 A
`4,158,750 A
`
`12/1977 Ashkin et a1.
`6/1979 Sakoe et a1.
`(Continued)
`
`FOREIGN PATENT DOCUMENTS
`
`CN
`DE
`
`101849821 B
`102010012987 A1
`
`7/2013
`10/2010
`
`(Continued)
`
`OTHER PUBLICATIONS
`
`Pan, Yingtian, et a1., “Hand-held arthroscopic optical coherence
`tomography for in vivo high-resolution imaging of articular carti-
`lage”, Journal of Biomedical Optics 8(4), Oct. 2003, pp. 648-654.
`(Continued)
`
`Primary Examiner 7 Tarifur Chowdhury
`Assistant Examiner 7 Md M Rahman
`
`(74) Attorney, Agent, or Firm 7 Brooks Kushman PC.
`
`(57)
`
`ABSTRACT
`
`A wearable device for use with a smart phone or tablet
`includes a measurement device having a plurality of LEDs
`generating a near-infrared input optical beam that measures
`physiological parameters. The measurement device includes
`lenses configured to receive and to deliver the input beam to
`skin which reflects the beam. The measurement device
`
`includes a reflective surface configured to receive and redi-
`rect the light from the skin, and a receiver configured to
`receive the reflected beam. The light source is configured to
`increase a signal-to-noise ratio of the input beam reflected
`from the skin by increasing the light intensity from the LEDs
`and modulation of the LEDs. The measurement device is
`
`configured to generate an output signal representing a non-
`invasive measurement on blood contained within the skin.
`
`The wearable device is configured to wirelessly communi-
`cate with the smart phone or tablet which receives and
`processes the output signal.
`
`(Continued)
`
`10 Claims, 16 Drawing Sheets
`
`1270
`/
`
`
`
` OUIFUT
`
`
`
`(
`12,77
`:gmm’r’sm””””””1
`EMONOCHROMATOR
`W
`LOCK-1N
`lnSbDETECTOR+
`;
`__,,
`
`PREAMP
`Ti
`5 AMPLIFIER g
`
`
`
`Page 1
`
`OM NI 2105
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`|PR2020-00175
`
`Page 1
`
`OMNI 2105
`IPR2020-00175
`
`

`

`US 9,757,040 B2
`
`Page 2
`
`Related U.S. Application Data
`
`(60) Provisional application No. 61/747,477, filed on Dec.
`31, 2012, provisional application No. 61/754,698,
`filed on Jan. 21, 2013.
`
`(51)
`
`(2006.01)
`(2006.01)
`(2006.01)
`(2006.01)
`(2014.01)
`(2006.01)
`(2006.01)
`(2006.01)
`(2014.01)
`(2006.01)
`(2006.01)
`(2006.01)
`(2006.01)
`(2006.01)
`(2006.01)
`(2006.01)
`(2006.01)
`
`Int. Cl.
`A613 5/1455
`G011 3/10
`G011 3/28
`G011 3/453
`G01N 21/359
`A613 5/145
`G01N 33/15
`G01N 33/49
`G01N 21/3563
`G01N 21/39
`G01N 33/02
`G01N 33/44
`G01N 21/88
`HOIS 3/30
`G011 3/14
`G011 3/18
`G01M 3/38
`(52) U.S. Cl.
`CPC .......... A613 5/00 75 (2013.01); A613 5/0086
`(2013.01); A613 5/1455 (2013.01); A613
`5/14532 (2013.01); A613 5/14546 (2013.01);
`A613 5/4547 (2013.01); G01] 3/108
`(2013.01); G01] 3/28 (2013.01); G01] 3/2823
`(2013.01); G01] 3/453 (2013.01); G01N
`21/359 (2013.01); G01N 21/3563 (2013.01);
`G01N 21/39 (2013.01); G01N 21/88
`(2013.01); G01N 33/02 (2013.01); G01N
`33/15 (2013.01); G01N 33/442 (2013.01);
`G01N 33/49 (2013.01); A613 2562/0233
`(2013.01); A613 2562/0238 (2013.01); A613
`2562/146 (2013.01); A613 2576/02 (2013.01);
`G01] 3/14 (2013.01); G01] 3/1838 (2013.01);
`G01] 2003/104 (2013.01); G01] 2003/2826
`(2013.01); G01M3/38 (2013.01); G01N
`2021/399 (2013.01); G01N 2201/061
`(2013.01); G01N 2201/062 (2013.01); G01N
`2201/08 (2013.01); G01N 2201/12 (2013.01);
`H015 3/302 (2013.01)
`(58) Field of Classification Search
`USPC .......................................................... 356/300
`
`See application file for complete search history.
`
`(56)
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`6,458,120
`6,462,500
`6,463,361
`6,480,656
`6,512,936
`6,534,012
`
`>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
`
`B1
`B1
`
`1/1992
`2/1992
`7/1992
`9/1992
`1/1993
`3/1993
`6/1993
`7/1993
`9/1993
`11/1993
`11/1993
`11/1993
`4/1994
`4/1994
`4/1994
`5/1994
`6/1994
`9/1994
`3/1995
`4/1995
`10/1995
`8/1996
`11/1996
`4/1997
`5/1997
`11/1997
`12/1997
`12/1997
`1/1998
`2/1998
`5/1998
`5/1998
`8/1998
`9/1998
`1/1999
`1/1999
`2/1999
`6/1999
`8/1999
`9/1999
`9/1999
`10/1999
`1/2000
`3/2000
`9/2000
`2/2001
`3/2001
`5/2001
`6/2001
`6/2001
`8/2001
`8/2001
`8/2001
`9/2001
`9/2001
`10/2001
`10/2001
`12/2001
`1/2002
`1/2002
`2/2002
`4/2002
`4/2002
`4/2002
`6/2002
`6/2002
`8/2002
`8/2002
`8/2002
`9/2002
`9/2002
`9/2002
`9/2002
`10/2002
`10/2002
`10/2002
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`1/2003
`3/2003
`
`Esterowitz et a1.
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`Huber
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`
`OMNI 2105
`
`|PR2020-00175
`
`Page 2
`
`OMNI 2105
`IPR2020-00175
`
`

`

`US 9,757,040 B2
`
`Page 3
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`(56)
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`B2
`B1
`B2
`B2
`B2
`B2
`B1
`B1
`B2
`B2
`B2
`B2
`B1
`B2
`B1
`B1
`B2
`B1
`B2
`B2
`B2
`B2
`B2
`B2
`B2
`B1
`B2
`B1
`B1
`B1
`B2
`B2
`B2
`B1
`B2
`B1
`B2
`B2
`B2
`B2
`B2
`B2
`B2
`B2
`B2
`B2
`B2
`B2
`B2
`A1
`A1
`A1
`A1
`A1
`A1
`A1
`A1
`A1
`A1
`A1
`A1
`A1
`A1
`A1
`A1
`A1
`A1
`A1
`A1
`A1
`A1
`A1
`
`4/2003
`5/2003
`7/2003
`8/2003
`8/2003
`8/2003
`9/2003
`10/2003
`10/2003
`12/2003
`12/2003
`5/2004
`7/2004
`8/2004
`9/2004
`10/2004
`11/2004
`1/2005
`3/2005
`4/2005
`4/2005
`9/2005
`1/2006
`3/2006
`4/2006
`6/2006
`11/2006
`1/2007
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`1/2008
`4/2008
`7/2008
`10/2008
`4/2009
`4/2009
`11/2009
`4/2010
`8/2010
`8/2010
`9/2010
`10/2010
`8/2011
`3/2012
`5/2012
`6/2013
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`Page 3
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`OMNI 2105
`IPR2020-00175
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`

`US 9,757,040 B2
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