Omni MedSci, Inc. v. Apple Inc.
`Case No. 2:18-cv-134-RWS (E.D. Tex.)
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`DEFENDANT’S INVALIDITY CONTENTIONS
`August 28, 2018
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`EXHIBIT P
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`EXHIBIT P-1, p.1
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`Case No. 2:18-cv-134-RWS (E.D. Tex.)
`Omni MedSci, Inc. v. Apple Inc.
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`Chart.
`renders those claims obvious alone and/or in view of at least any of the references identified in Apple’s Obviousness Combinations
`US Patent No. 9,241,676 to Lisogurki (“Lisogurki”) anticipates the asserted claims of U.S. Patent No. 9,651,533 (“the ’533 Patent”) or
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`each dependent claim, the disclosures cited for the claim from which it depends are incorporated by reference.
`agreement or view as to the meaning, definiteness, written description support for, or enablement of any of the asserted claims. For
`that Omni contends the claims are not invalid under 35 U.S.C. § 112. However, Apple’s below contentions do not represent Apple’s
`As set forth in Apple’s Invalidity Contentions, the below contentions apply the prior art in part in accordance with Apple’s assumption
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`§§ 102(a), (b), and (d)
`§§ 102(a), (b), and (e) (pre-AIA)
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`Prior Art Status:
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`May 31, 2012/Jan. 26, 2016
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`U.S. Patent No. 9,651,533 vs Lisogurki
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`EXHIBIT P-1
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`Priority Date/Publication Date:
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`EXHIBIT P-1, p.2
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`combination thereof, using any suitable calculation techniques. In some embodiments, the system
`determine pulse amplitude, respiration, blood pressure, other suitable parameters, or any
`wavelengths of light and a ratio-of-ratios calculation. The system also may identify pulses and
`known in the art. For example, the system may determine blood oxygen saturation using two
`“The system may process data to determine physiological parameters using techniques well
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`the oxygen saturation of hemoglobin in arterial blood.” Lisogurski, 3:61-4:3.
`systems that measure and display various blood flow characteristics including, but not limited to,
`blood sample taken from the patient). Pulse oximeters may be included in patient monitoring
`saturation of a patient's blood (as opposed to measuring oxygen saturation directly by analyzing a
`One common type of oximeter is a pulse oximeter, which may non-invasively measure the oxygen
`“An oximeter is a medical device that may determine the oxygen saturation of an analyzed tissue.
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`typically using one or more physiological sensors.” Lisogurski, 3:43-46.
`physiological monitoring system may monitor one or more physiological parameters of a patient,
`“The present disclosure is directed towards power optimization in a medical device. A
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`Lisogurski, Abstract.
`pulses. In some embodiments, the system may vary parameters in response to an external trigger.”
`parameters in a way substantially synchronous with physiological pulses, for example, cardiac
`generate a light drive signal for a second light source. In some embodiments, the system may vary
`thereof. In some embodiments, the system may use information from a first light source to
`include light intensity, firing rate, duty cycle, other suitable parameters, or any combination
`signal from a light source such that power consumption is reduced or optimized. Parameters may
`parameters. The system may vary parameters of a light drive signal used to generate the photonic
`“A physiological monitoring system may use photonic signals to determine physiological
`measurement system.”
`To the extent the preamble is limiting, Lisogurki discloses and/or renders obvious “[a]
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`Lisogurski (US 9,241,676)
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`CHART ONE: U.S. Patent No. 9,651,533 vs Lisogurki
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`comprising:
`[5] A measurement system,
`Asserted Claim of ’533 Patent
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`EXHIBIT P-1, p.3
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`determine physiological parameters.” Lisogurski, 4:52-62.
`may use information from external sources (e.g., tabulated data, secondary sensor devices) to
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`Lisogurski (US 9,241,676)
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`Asserted Claim of ’533 Patent
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`EXHIBIT P-1, p.4
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`Case No. 2:18-cv-134-RWS (E.D. Tex.)
`Omni MedSci, Inc. v. Apple Inc.
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`Lisogurski (US 9,241,676)
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`Asserted Claim of ’533 Patent
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`EXHIBIT P-1, p.5
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`EXHIBIT P-1, p.6
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`first light source may be a high efficiency infrared (IR) LED while the one or more additional light
`that is a more efficient light source than the one or more additional light sources. For example, the
`may include a first light source (e.g., a light source powered at full or regular brightness) of a type
`power optimization techniques, or any combination thereof. In some embodiments, the system
`additional light sources, alter the modulation of the additional light sources, perform other suitable
`of interest in the cardiac cycle. The system may, according to the periods of interest, power
`or unrelated. In some embodiments, the system may use the first light source to determine periods
`technique. The first and second cardiac cycle modulation techniques may be the same, correlated,
`modulation technique and a second light source according to a second cardiac modulation
`embodiments, the system may operate a first light source according to a first cardiac cycle
`one or more additional light sources in a switched or otherwise modulated mode. In some
`sources, the system may operate a first light source at full or regular brightness, while operating
`sources using a plurality of modulation techniques. For example, in a system with two light
`“In some embodiments of cardiac cycle modulation, the system may modulate multiple light
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`oxygen saturation.” Lisogurski, 4:45-48.
`oxygenated blood will absorb relatively less red light and more IR light than blood with a lower
`“Red and infrared (IR) wavelengths may be used because it has been observed that highly
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`the IR wavelength may be between about 800 nm and about 1000 nm.” Lisogurski, 10:56-58.
`“In one embodiment, the Red wavelength may be between about 600 nm and about 700 nm, and
`wavelengths is a near-infrared wavelength between 700 nanometers and 2500 nanometers.”
`Lisogurki discloses and/or renders obvious “wherein at least a portion of the one or more optical
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`See CHART ONE: ’533 Patent, Claim Element 13A below.
`optical beam with one or more optical wavelengths.”
`sources that are light emitting diodes, the light emitting diodes configured to generate an output
`Lisogurki discloses and/or renders obvious “a light source comprising a plurality of semiconductor
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`Lisogurski (US 9,241,676)
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`nanometers and 2500 nanometers,
`wavelength between 700
`wavelengths is a near-infrared
`the one or more optical
`[5B] wherein at least a portion of
`optical wavelengths,
`optical beam with one or more
`configured to generate an output
`diodes, the light emitting diodes
`sources that are light emitting
`plurality of semiconductor
`[5A] a light source comprising a
`Asserted Claim of ’533 Patent
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`EXHIBIT P-1, p.7
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`thereof. Generally, conventional servo algorithms vary parameters at a slower rate than cardiac
`and detector spacing changes, sensor positioning, other suitable parameters, or any combination
`algorithms may adjust the light drive signals due to, for example, ambient light changes, emitter
`combination of cardiac cycle modulation and drive cycle modulation. Conventional servo
`“In some embodiments, conventional servo algorithms may be used in addition to any
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`Lisogurski, 5:48-54.
`while drive cycle modulation may have a period around, for example, 1.6 milliseconds.”
`intensity signals. Cardiac cycle modulation may have a period of, for example, around 1 second,
`frequency modulation technique that the system may use to generate one or more wavelengths of
`“As used herein, “drive cycle modulation” (described below) will refer to a relatively higher
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`Lisogurski, Abstract.
`pulses. In some embodiments, the system may vary parameters in response to an external trigger.”
`parameters in a way substantially synchronous with physiological pulses, for example, cardiac
`generate a light drive signal for a second light source. In some embodiments, the system may vary
`thereof. In some embodiments, the system may use information from a first light source to
`include light intensity, firing rate, duty cycle, other suitable parameters, or any combination
`signal from a light source such that power consumption is reduced or optimized. Parameters may
`parameters. The system may vary parameters of a light drive signal used to generate the photonic
`“A physiological monitoring system may use photonic signals to determine physiological
`by increasing a pulse rate of at least one of the plurality of semiconductor sources.”
`ratio by increasing a light intensity from at least one of the plurality of semiconductor sources and
`Lisogurki discloses and/or renders obvious “the light source configured to increase signal-to-noise
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`physiological parameters.” Lisogurski, 7:38-8:3.
`first light source may be used only for controlling the second light source and not for determining
`control one or more second light sources at wavelengths of interest. In this case, the light from the
`that is not at a wavelength of interest for physiological parameter determination may be used to
`may be used only to control a second light source. For example, a highly efficient first light source
`source may be selected based on efficiency parameters and information from the first light source
`sources may be lower efficiency red LEDs or laser diodes. In some embodiments, the first light
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`semiconductor sources;
`one of the plurality of
`increasing a pulse rate of at least
`of semiconductor sources and by
`from at least one of the plurality
`by increasing a light intensity
`to increase signal-to-noise ratio
`[5C] the light source configured
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`Lisogurski (US 9,241,676)
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`Asserted Claim of ’533 Patent
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`EXHIBIT P-1, p.8
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`system may vary parameters related to the light drive signal including drive current or light
`closely related to the period of the cardiac cycle, thus generating a cardiac cycle modulation. The
`example, the system may generate a light drive signal that varies with a period the same as or
`photonic signals varies substantially synchronously with physiological pulses of the subject. For
`“The system may generate the light drive signal such that a parameter of the emitted one or more
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`constant light output in response to noise, patient motion, or ambient light.” Lisogurski, 9:46-60.
`or motion. In some embodiments, the system may change from a modulated light output to a
`fiducial and other points of interest related to physiological parameters and those related to noise
`cardiac cycle because the system may require increased signal amplitudes to differentiate between
`signal-to-noise ratio. In some embodiments, the system may increase brightness throughout the
`The system may increase the brightness of the light sources in response to the noise to improve the
`receive, for example, an increased level of background noise in the signal due to patient motion.
`level of noise, ambient light, other suitable reasons, or any combination thereof. The system may
`“In some embodiments, the system may alter the cardiac cycle modulation technique based on the
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`signal-to-noise ratio.” Lisogurski, 9:46-52.
`The system may increase the brightness of the light sources in response to the noise to improve the
`receive, for example, an increased level of background noise in the signal due to patient motion.
`level of noise, ambient light, other suitable reasons, or any combination thereof. The system may
`“In some embodiments, the system may alter the cardiac cycle modulation technique based on the
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`Lisogurski, 5:55-6:6.
`by an analog to digital converter. In response, the system may increase the emitter brightness.”
`In a further example, the quality of a low amplitude signal may be degraded by quantization noise
`convertor. In response to a signal with high amplitudes, the system may reduce emitter brightness.
`range. For example, a signal with amplitudes that are large may saturate an analog to digital
`part to keep received signal levels within the range of an analog to digital converter's dynamic
`due to ambient light every several seconds. The system may use conventional servo algorithms in
`cycle modulation. For example, a conventional servo algorithm may adjust drive signal brightness
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`Lisogurski (US 9,241,676)
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`Asserted Claim of ’533 Patent
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`EXHIBIT P-1, p.9
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`wavelength is absorbed or reflected, less light of that wavelength is received from the tissue by
`the absorbance and/or reflectance of light in the tissue. That is, when more light at a certain
`intensity of the received light into an electrical signal. The light intensity may be directly related to
`enter detector 140 after passing through the subject's tissue. Detector 140 may convert the
`the array may be configured to detect an intensity of a single wavelength. In operation, light may
`and IR wavelengths. In some embodiments, an array of sensors may be used and each sensor in
`“In some embodiments, detector 140 may be configured to detect the intensity of light at the Red
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`reflected by or has traveled through the subject’s tissue.” Lisogurski, 17:39-42.
`“One or more detector 318 may also be provided in sensor unit 312 for detecting the light that is
`to a sample.”
`configured to receive a portion of the output optical beam and to deliver an analysis output beam
`Lisogurki discloses and/or renders obvious “an apparatus comprising a plurality of lenses
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`analysis output beam to a sample
`optical beam and to deliver an
`receive a portion of the output
`plurality of lenses configured to
`[5D] an apparatus comprising a
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`emitter firing rate) relates to an increased sampling rate.” Lisogurski, 35:24-31.
`decreased sampling rate. Similarly, decreasing the duration of the “off” periods (i.e., increasing the
`2A. Increasing the duration of the “off” periods (i.e., decreasing the emitter firing rate) relates to a
`For example, the time between “on” periods may be the length of time of “off” period 220 of FIG.
`“In some embodiments, the sampling rate may represent the amount of time between “on” periods.
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`waveforms.” Lisogurski, 27:44-55.
`signals with one or more step functions. Continuous modulations may include sinusoidal
`of discrete and/or continuous modulations. For example, discrete modulations may include drive
`the “on” and “off” states are merely exemplary and that the system may use any suitable variations
`parameters, other suitable parameters, or any combination thereof. It will also be understood that
`parameters including drive current or light brightness, duty cycle, firing rate, modulation
`illustrated by light drive signal 1010) is merely exemplary and may include modulation of
`“It will also be understood that modulation of the light drive signal (i.e., the “on” and “off” states
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`combination thereof.” Lisogurski, 25:46-55.
`brightness, duty cycle, firing rate, modulation parameters, other suitable parameters, or any
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`Lisogurski (US 9,241,676)
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`Asserted Claim of ’533 Patent
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`EXHIBIT P-1, p.10
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`circuitry 150 may perform various analog and digital processing of the detector signal. One
`processing circuitry 150 as it processes the output signal of detector 140. Front end processing
`term “detection signal,” as used herein, may refer to any of the signals generated within front end
`detector 140 and provide one or more processed signals to back end processing circuitry 170. The
`“Referring back to FIG. 1, front end processing circuitry 150 may receive a detection signal from
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`before being transmitted to monitor 104.” Lisogurski, 11:9-27.
`subject's tissue). In some embodiments, the detection signal may be preprocessed by sensor 102
`parameters may be determined (e.g., based on the absorption of the Red and IR wavelengths in the
`detection signal to monitor 104, where the detection signal may be processed and physiological
`detector 140. After converting the received light to an electrical signal, detector 140 may send the
`wavelength is absorbed or reflected, less light of that wavelength is received from the tissue by
`the absorbance and/or reflectance of light in the tissue. That is, when more light at a certain
`intensity of the received light into an electrical signal. The light intensity may be directly related to
`enter detector 140 after passing through the subject's tissue. Detector 140 may convert the
`the array may be configured to detect an intensity of a single wavelength. In operation, light may
`and IR wavelengths. In some embodiments, an array of sensors may be used and each sensor in
`“In some embodiments, detector 140 may be configured to detect the intensity of light at the Red
`embodiments, sensor 102 and monitor 104 may be part of an oximeter.” Lisogurski, 10:42-47.
`monitor 104 for generating and processing physiological signals of a subject. In some
`with some embodiments of the present disclosure. System 100 may include a sensor 102 and a
`“FIG. 1 is a block diagram of an illustrative physiological monitoring system 100 in accordance
`output signal.”
`portion of the analysis output beam reflected or transmitted from the sample and to generate an
`Lisogurki discloses and/or renders obvious “a receiver configured to receive and process at least a
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`sensor 102 before being transmitted to monitor 104.” Lisogurski, 11:9-20.
`subject's tissue). In some embodiments, the detection signal may be preprocessed by
`parameters may be determined (e.g., based on the absorption of the Red and IR wavelengths in the
`detection signal to monitor 104, where the detection signal may be processed and physiological
`detector 140. After converting the received light to an electrical signal, detector 140 may send the
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`an output signal,
`from the sample and to generate
`beam reflected or transmitted
`portion of the analysis output
`receive and process at least a
`[5E] a receiver configured to
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`Lisogurski (US 9,241,676)
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`Asserted Claim of ’533 Patent
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`EXHIBIT P-1, p.11
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`Information may be encoded in a calibration resistor or non-volatile calibration memory included
`example, the emission intensity relative to a drive signal may be known for a particular LED.
`components, empirical data, any other suitable techniques, or any combination thereof. For
`the linearity. Corrections may be determined using a calibration step, lookup tables for known
`combination thereof. For example, the system may adjust the drive signal to an LED to improve
`signal gain, by adjusting received signal processing, by any other suitable method, or any
`may account for non-linearity by adjusting drive signals, by adjusting amplification of received
`emitted intensity of light from an LED may not vary linearly with the drive current. The system
`“In some embodiments, the system may correct for non-linearity of light sources. For example, the
`to the light source.”
`Lisogurki discloses and/or renders obvious “wherein the receiver is configured to be synchronized
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`See also Lisogurski, Fig. 2A, 2B, 10:48-11:8; 17:42-45, 19:40-43, 26:26-32.
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`different locations on a subject's body.” Lisogurski, 17:30-53.
`(e.g., a photoacoustic sensor). Multiple sensor units may be capable of being positioned at two
`the same type of sensor unit as sensor unit 312, or a different sensor unit type than sensor unit 312
`embodiments described herein with reference to sensor unit 312. An additional sensor unit may be
`or more additional sensor units (not shown) that may, for example, take the form of any of the
`multiple light sources and detectors, which may be spaced apart. System 310 may also include one
`of light source 316 and detector 318 may be used. In an embodiment, sensor unit 312 may include
`the light that is reflected by or has traveled through the subject's tissue. Any suitable configuration
`subject's tissue. One or more detector 318 may also be provided in sensor unit 312 for detecting
`may include one or more light source 316 for emitting light at one or more wavelengths into a
`monitor 314. In some embodiments, sensor unit 312 may be part of an oximeter. Sensor unit 312
`physiological monitoring system 100 of FIG. 1. System 310 may include sensor unit 312 and
`components of physiological monitoring system 310 may include one or more components of
`accordance with some embodiments of the present disclosure. In some embodiments, one or more
`“FIG. 3 is a perspective view of an embodiment of a physiological monitoring system 310 in
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`FIG. 2B.” Lisogurski, 12:41-51; see id., 12:52-14:10 (describing processing of the output signal).
`suitable detector signal that may be received by front end processing circuitry 150 is shown in
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`the light source;
`configured to be synchronized to
`[5F] wherein the receiver is
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`Lisogurski (US 9,241,676)
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`Asserted Claim of ’533 Patent
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`EXHIBIT P-1, p.12
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`processing circuitry 150.” Lisogurski, 11:33-49.
`circuitry 170 may use the timing control signals to coordinate its operation with front end
`with the light drive signal based on the timing control signals. In addition, the back end processing
`circuitry 150 may synchronize the operation of an analog-to-digital converter and a demultiplexer
`signals to operate synchronously with light drive circuitry 120. For example, front end processing
`the timing control signals. The front end processing circuitry 150 may use the timing control
`generate a light drive signal, which may be used to turn on and off the light source 130, based on
`timing control signals to coordinate their operation. For example, light drive circuitry 120 may
`these components. In some embodiments, control circuitry 110 may be configured to provide
`150, and back end processing circuitry 170, and may be configured to control the operation of
`“Control circuitry 110 may be coupled to light drive circuitry 120, front end processing circuitry
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`10:23-38; see id., 34:14-25.
`interpolate the digitized signal such that the rate of the processed signal is constant.” Lisogurski,
`output and at a high rate during a period of high light output. The system may decimate or
`For example, the system may sample the received signal at a low rate during a period of low light
`sampling rate. The modulations of the light drive signal and the sampling rate may be correlated.
`other periods. In some embodiments, the system may modulate both a light drive signal and a
`example, the system may sample at a high rate during a period of interest and at a low rate during
`the digitizer rate may be modulated using a technique correlated to a cardiac cycle modulation. For
`particular rate. In some embodiments, the digitizer rate may be constant. In some embodiments,
`The system may digitize a received signal using an analog to digital converter operating at a
`“In some embodiments, the system may optimize power consumption by varying a sampling rate.
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`signals.” Lisogurski, 7:12-37.
`a known range of drive signals, and in a non-linear relationship outside that range of drive
`component may operate with a linear relationship between drive signal and output intensity within
`operating range of a component (e.g., an LED) may be limited. In some embodiments, a
`with those generated in response to a low current drive signal. In some embodiments, the
`comparing the intensity of received signals generated in response to a high current drive signal
`in the sensor or the system. In another example, the system may calibrate emission output by
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`Lisogurski (US 9,241,676)
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`Asserted Claim of ’533 Patent
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`EXHIBIT P-1, p.13
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`emitter firing rate) relates to an increased sampling rate.” Lisogurski, 35:24-31.
`decreased sampling rate. Similarly, decreasing the duration of the “off” periods (i.e., increasing the
`2A. Increasing the duration of the “off” periods (i.e., decreasing the emitter firing rate) relates to a
`For example, the time between “on” periods may be the length of time of “off” period 220 of FIG.
`“In some embodiments, the sampling rate may represent the amount of time between “on” periods.
`(describing processing of the output signal).
`222 may be present in the detector waveform.” Lisogurski, 12:52-13:3; see id., 13:4-14:10
`the valleys, detector current waveform 214 may not fall all of the way to zero. Rather, dark current
`light is being emitted by the light source. While no light is being emitted by a light source during
`valleys of detector current waveform may be synchronous with periods of time during which no
`generated in response to a light source being driven by the light drive signal of FIG 2A. The
`source, such as light source 130 of FIG 1. For example, detector current waveform 214 may be
`waveform 214 may be synchronous with light ‘on’ periods driving one or more emitters of a light
`214 may be proportional to the light incident upon the detector. The peaks of detector current
`1, when light is being emitted from a light source. The amplitude of detector current waveform
`waveform 214 may represent current signals provided by a detector, such as detector 140 of FIG.
`accordance with some embodiments of the present disclosure. The peaks of detector current
`“FIG. 2B shows an illustrative plot of detector signal 214 that may be generated by a sensor in
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`FIG. 2B.” Lisogurski, 12:41-51.
`suitable detector signal that may be received by front end processing circuitry 150 is shown in
`circuitry 150 may perform various analog and digital processing of the detector signal. One
`processing circuitry 150 as it processes the output signal of detector 140. Front end processing
`term “detection signal,” as used herein, may refer to any of the signals generated within front end
`detector 140 and provide one or more processed signals to back end processing circuitry 170. The
`“Referring back to FIG. 1, front end processing circuitry 150 may receive a detection signal from
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`Lisogurski (US 9,241,676)
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`Asserted Claim of ’533 Patent
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`EXHIBIT P-1, p.14
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`EXHIBIT P-1, p.15
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`Case No. 2:18-cv-134-RWS (E.D. Tex.)
`Omni MedSci, Inc. v. Apple Inc.
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`switches, a microphone, a joy stick, a touch pad, or any other suitable input device. The inputs
`include any type of user input device such as a keyboard, a mouse, a touch screen, buttons,
`“User interface 180 may include user input 182, display 184, and speaker 186. User input 182 may
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`embodiments, sensor 102 and monitor 104 may be part of an oximeter.” Lisogurski, 10:42-47.
`monitor 104 for generating and processing physiological signals of a subject. In some
`with some embodiments of the present disclosure. System 100 may include a sensor 102 and a
`“FIG. 1 is a block diagram of an illustrative physiological monitoring system 100 in accordance
`microprocessor and a touch screen.”
`wireless transmitter, a display, a microphone, a speaker, one or more buttons or knobs, a
`Lisogurki discloses and/or renders obvious “a personal device comprising a wireless receiver, a
`
`Lisogurski (US 9,241,676)
`
`
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`screen,
`microprocessor and a touch
`more buttons or knobs, a
`microphone, a speaker, one or
`wireless transmitter, a display, a
`comprising a wireless receiver, a
`[5G] a personal device
`Asserted Claim of ’533 Patent
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`OMNI 2126 - IPR2020-00175
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`

`

`EXHIBIT P-1, p.16
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`Case No. 2:18-cv-134-RWS (E.D. Tex.)
`Omni MedSci, Inc. v. Apple Inc.
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`only. In some embodiments the functionality of some of the components may be combined in a
`and described as separate components are shown and described as such for illustrative purposes
`“It will be understood that the components of physiological monitoring system 100 that are shown
`
`expansion cards.” Lisogurski, 15:19-65.
`interface 190 may include an internal bus such as, for example, one or more slots for insertion of
`Type-A connector (e.g., plug and/or socket) and cable. In some embodiments, communications
`other devices (e.g., remote memory devices storing templates) using a four-pin USB standard
`universal serial bus (USB) protocol (e.g., USB 2.0, USB 3.0), and may be configured to couple to
`standards), or both. For example, communications interface 190 may be configured using a
`standards), wireless communication (e.g., using WiFi, IR, WiMax, BLUETOOTH, UWB, or other
`interface 190 may be configured to allow wired communication (e.g., using USB, RS-232 or other
`protocols, any other suitable hardware or software, or any combination thereof. Communications
`connectors, ports, communications buses, communications protocols, device identification
`interface 190 may include one or more receivers, transmitters, transceivers, antennas, plug-in
`server or other workstations, a display, or any combination thereof. Communications
`which may allow monitor 104 to communicate with electronic circuitry, a device, a network, a
`devices. Communications interface 190 may include any suitable hardware, software, or both,
`Communication interface 190 may enable monitor 104 to exchange information with external
`
`patient's physiological parameters are not within a predefined normal range.
`used in various embodiments, such as for example, sounding an audible alarm in the event that a
`display device. Speaker 186 within user interface 180 may provide an audible sound that may be
`display, a flat panel display such a liquid crystal display or plasma display, or any other suitable
`combination thereof. Display 184 may include any type of display such as a cathode ray tube
`information, respiration rate information, blood pressure, any other parameters, and any
`saturation generated by monitor 104(referred to as an “SpO2” measurement), pulse rate
`Additionally, display 184 may display, for example, an estimate of a subject's blood oxygen
`as, for example, age ranges or medication families, which the user may select using user input 182.
`patient and display 184 may exhibit a list of values which may generally apply to the patient, such
`diagnosis, medications, treatments, and so forth. In an embodiment, the subject may be a medical
`received by user input 182 can include information about the subject, such as age, weight, height,
`
`Lisogurski (US 9,241,676)
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`Asserted Claim of ’533 Patent
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`OMNI 2126 - IPR2020-00175
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`

`

`EXHIBIT P-1, p.17
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`Case No. 2:18-cv-134-RWS (E.D. Tex.)
`Omni MedSci, Inc. v. Apple Inc.
`
`embodiments, sensor 102 and monitor 104 may be part of an oximeter.” Lisogurski, 10:42-47.
`monitor 104 for generating and processing physiological signals of a subject. In some
`with some embodiments of the present disclosure. System 100 may include a sensor 102 and a
`“FIG. 1 is a block diagram of an illustrative physiological monitoring system 100 in accordance
`at least a portion of the output signal.”
`Lisogurki discloses and/or renders obvious “the personal device configured to receive and process
`
`See also Lisogurski, 17:54-18:67.
`Lisogurski, 15:66-16:16.
`of the components of physiological monitoring system 100 can be realized in processor circuitry.”
`components may be performed in a different order or may not be required. In an embodiment, all
`processing circuitry 170, or both. In other embodiments, the functionality of one or more of the
`control circuitry 110 may be performed in front end processing circuitry 150, in back end
`herein may be divi