UNITED STATES INTERNATIONAL TRADE COMMISSION
`
`UNITED STATES INTERNATIONAL TRADE COMMISSION
`Washington, D.C.
`Washington,
`D.C.
`Before the Honorable Delbert R. Terrill, Jr.
`
`
`Before the Honorable Delbert R. Terrill,
`Jr.
`
`In the Matter of
`
`In the Matter of
`
`INv. No. 337-TA-515
`CERTAIN INJECTABLE IMPLANT COMPOSITIONS
`
`CERTAIN INJECTABLE IMPLANT COMPOSITIONS INV. No. 337-TA-515
`
`IDENTIFICATION OF EXPERT WITNESSES
`
`IDENTIFICATION OF EXPERT WITNESSES
`
`Pursuant to Order No. 3, Respondents Q -Med Aktiebolag and Medicis Aesthetics, Inc.
`
`
`
`
`
`Pursuant to Order No. 3, Respondents Q-Med Aktiebolag and Medicis Aesthetics, Inc.
`
`(collectively, "Respondents ") hereby identify the following individuals who may appear in. this
`who may appe.� in. trus
`
`
`
`(collectively, "Respondents") hereby identify the following individuals
`
`investigation as expert witnesses on behalf of Respondents:
`
`
`
`
`investigation as expert witnesses on behalf of Respondents:
`
`Dr. Milos Chvapil
`1. Dr. Milos Chvapil
`1.
`5655 N. Mina Vista
`5655 N. Mina Vista
`Tucson, Arizona 85718
`
`Tucson, Arizona 85718
`
`.) .:· :,
`
`--
`. '1
`;
`
`\
`...... J,
`
`., ...
`.,
`
`w
`Area of Expertise: Dr. Chvapil is an expert in dermal fillers used in soft tissue
`
`
`
`Area of Expertise: Dr. Chvapil is an expert in dermal fillers used in soft tissue
`augmentation.
`augmentation.
`
`Dr. Marcel E. Nimni
`2.
`
`2. Dr. Marcel E. Nimni
`Professor of Surgery, Orthopedics, Biochemistry & Molecular Biology and
`
`
`
`
`
`
`Professor of Surgery, Orthopedics, Biochemistry & Molecular Biology and
`Biomedical Engineering and Director of Tissue Engineering Laboratories
`
`
`
`
`
`Biomedical Engineering and Director of Tissue Engineering Laboratories
`University of Southern California Schools of Medicine and Engineering
`
`
`
`
`
`University of Southern California Schools of Medicine and Engineering
`Los Angeles, California 90033
`
`
`Los Angeles, California 90033
`
`Area of Expertise: Dr. Nimni is an expert in polymer -based medical implants.
`
`
`
`
`Area of Expertise: Dr. Nimni is an expert in polymer-based medical implants.
`
`Dr. Dale P. De Vore
`3.
`3. Dr. Dale P. De Vore
`3 Warwick Drive
`3 Warwick Drive
`Chelmsford, Massachusetts 01824
`
`
`Chelmsford, Massachusetts O 1824
`
`Areas of Expertise: Dr. De Vore is an expert in polymer -based medical implants.
`
`
`
`Areas of Expertise: Dr. De Vore is an expert in polymer-based medical implants.
`
`f'roflenrtrrrr v. Allergara
`IPR2019-01505,
`ai,
`DeVore Dopo. Ex. 40
`1 of 106
`
`1 of 106
`
`ALL 2140
`PROLLENIUM V. ALLERGAN
`IPR2019-01505 et al.
`
`

`

`Dr. Gottfried Lemperle
`4.
`4. Dr. Gottfried Lemperle
`
`Artes Medical, Inc.
`
`Artes Medical, Inc.
`4660 La Jolla Village Drive, Suite 825
`
`
`4660 La Jolla Village Drive, Suite 825
`San Diego, California 92122
`
`
`San Diego, California 92122
`
`Area of Expertise: Dr. Lemperle is an expert in dermal fillers used in soft tissue
`
`
`
`
`
`Area of Expertise: Dr. Lemperle is an expert in dermal fillers used in soft tissue
`augmentation.
`
`augmentation.
`
`Chemir Analytical Services
`5.
`5. Chemir Analytical Services
`
`2672 Metro Boulevard
`2672 Metro Boulevard
`Maryland Heights, Missouri 63043
`
`Maryland Heights, Missouri 63043
`
`Chemir Employees: Christopher J. Andren, Director; David Dowell, Ph.D.;
`
`
`
`
`
`Chemir Employees: Christopher J. Andren, Director; David Dowell, Ph.D.;
`Leonard O. Rosik, Ph.D.; and Salvatore Giandinoto, Ph.D.
`
`
`
`
`Leonard 0. Rosik, Ph.D.; and Salvatore Giandinoto, Ph.D.
`
`Area of Expertise: Chemical Analysis
`
`
`Area of Expertise: Chemical Analysis
`
`The curricula vitae for Dr. Chvapil, Dr. Nimni, Dr. De Vore, Dr. Lemperle and the Chemir
`
`
`
`
`The curricula vitae for Dr. Chvapil, Dr. Nimni, Dr. De Vore, Dr. Lemperle and the Chemir
`
`employees are attached hereto as Exhibits A - H, respectively.
`
`
`
`employees are attached hereto as Exhibits A -H, respectively.
`
`+F
`
`s
`
`T!
`
`Respectfully submitted,
`
`Respectfully submitted,
`��?11��
`?fi
`Maureen F. Browne
`Maureen F. Browne
`Tom M. Schaumberg
`Tom M. Schaumberg
`David F. Nickel
`David F. Nickel
`Rodney R. Sweetland, III
`Rodney R. Sweetland, III
`Adduci, Mastriani & Schaumberg, L.L.P.
`
`
`
`Adduci, Mastriani & Schaumberg, L.L.P.
`1200 Seventeenth Street, N.W.
`
`
`1200 Seventeenth Street, N.W.
`Washington, DC 20036
`
`Washington, DC 20036
`(202) 467 -6300
`(202)467-6300
`
`William J. McNichol, Jr.
`
`
`William J. McNichol, Jr.
`Tracy Z. Frisch
`Tracy Z. Frisch
`Maryellen Feehery
`Maryellen Feehery
`Jeanine A. Graham
`
`Jeanine A. Graham
`Reed Smith LLP
`Reed Smith LLP
`2500 One Liberty Place
`2500 One Liberty Place
`1650 Market Street
`1650 Market Street
`Philadelphia, Pennsylvania 19103
`
`Philadelphia, Pennsylvania 19103
`(215) 851 -8100
`(215)851-8100
`
`COUNSEL FOR MEDICIS AESTHETICS, INC.
`
`COUNSEL FOR MEDICIS AESTHETICS, INC.
`AND Q -MED AKTIEBOLAG
`AND Q-MED AKTIEBOLAG
`
`2 of 106
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`2 of 106
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`

`

`Robert A. Bourque
`Robert A. Bourque
`Noah Leibowitz
`Noah Leibowitz
`Mariya Treisman
`Mariya Treisman
`Anna DiGabriele
`Anna DiGabriele
`Reynelle Brown
`
`Reynelle Brown
`Simpson Thacker & Bartlett LLP
`
`
`
`Simpson Thacher & Bartlett LLP
`425 Lexington Avenue
`
`425 Lexington Avenue
`New York, New York 10017 -3954
`
`New York, New York 10017-3954
`(212)455-3595
`(212) 455 -3595
`
`COUNSEL FOR Q -MED AKTIEBOLAG
`COUNSEL FOR Q-MED AKTIEBOLAG
`
`Dated: September 7, 2004
`
`Dated: September 7, 2004
`
`MEDI704704
`MEDl704704
`
`3 of 106
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`3 of 106
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`

`

`CURRICULUM VITAE
`
`Milos Chvapil, M.D., Ph.D., D.Sc.
`
`PERSONAL:
`
`Place of Birth:
`Kladno, Czechoslovakia
`
`
`September 29, 1928
`Date of Birth:
`, wife -Milena, two children
`Married
`
`Marital Status:
`June 1974
`U.S. Citizenship:
`544-52-2002
`
`Social Security Number:
`857185655 North Mina Vista, Tucson, Arizona,
`
`
`
`Residence:
`
`
`business: (602) 626-6637 home: (602) 299-6053
`Telephone:
`
`
`
`EDUCATION AND TRAINING:
`
`�D_eg._.._r_e_e
`
`_G_ra_n_te_d ____ �Ins_ti_tu_t1�· o_n (Czechoslovakia)
`
`
`Discipline
`
`1947
`1952-M.D.
`1956-Ph.D.
`1965 -D.Sc.
`
`Gymnasium (College)
`
`Charles University Medical School General Medicine
`
`
`
`
`
`
`
`Czechoslovak Academy of Sciences Biochemistr
`y
`
`
`
`Charles University Medical School Experimental
`
`Pathological/Physiology Dept. Pathology
`
`APPOINTMENTS AND OFFICES:
`
`
`
`
`1992 June Retired as Professor Emeritus,Surgery
`
`1976
`
`1973
`
`1992 Head,Surgical Biology.Dept.Surgery
`
`
`
`
`College of Medicine, University of Arizona
`
`Tucson, Arizona
`
`1983 Director of Research Laboratories
`
`
`
`
`
`
`
`Section of Surgical Biology, Department of Surgery
`
`
`
`College of Medicine, University of Arizona
`
`Tucson, Arizona
`
`1970 -1992
`
`Head,
`Section of Surgical Biology, Department of Surgery
`
`
`
`
`
`
`
`College of Medicine, University of Arizona
`
`Tucson, Arizona
`
`1969
`
`1970 Visiting Professor of Medicine
`
`
`
`
`
`School of Medicine, University of Miami
`Miami, Florida
`
`4 of 106
`
`

`

`1968
`1968
`
`-
`-
`
`1965
`1965
`
`1963
`1963
`
`1959
`1959
`
`1958
`1958
`
`-
`-
`
`-
`-
`
`1952
`1952
`
`-
`-
`
`Scientific Fellowship
`1969
`Scientific Fellowship
`1969
`Max Planck Institut fur Eiweiss und Lederforschung
`Max Planck Institut fur Eiweiss und Lederforschung
`Munich, Germany
`Munich, Germany
`
`Associate Professor of Experimental Pathology
`Associate Professor of Experimental Pathology
`Charles University Medical School
`Charles University Medical School
`Prague, Czechoslovakia
`Prague, Czechoslovakia
`
`Fellowship with D. S. Jackson, prof. of biochemistry
`Fellowship with D.S. Jackson, prof.of biochemistry
`Department of Surgery, Oregon University Medical
`Department of Surgery, Oregon University Medical
`
`Head, Division of Occupational Diseases
`1968
`Head, Division of Occupational Diseases
`1968
`Institute of Industrial Hygiene and Occupational Diseases
`Institute of Industrial Hygiene and Occupational Diseases
`
`1968
`1968
`
`Consulting Scientist for Ministry of Food Industry
`Consulting Scientist for Ministry of Food Industry
`in
`the Field of Artificial Collagen Casings;
`in the Field of Artificial Collagen Casings;
`Ministry of Light Industry in the Field of Artificial
`Ministry of Light Industry in the Field of Artificial
`Leather
`Leather
`Prague, Czechoslovakia
`Prague, Czechoslovakia
`1956
`Industrial Hygiene and
`Scientist, Institute of
`Industrial Hygiene and
`Institute of
`Scientist,
`1956
`Occupational Diseases, Prague, Czechoslovakia
`Occupational Diseases, Prague, Czechoslovakia
`
`Prag
`Prag
`
`MEMBERSHIPS :
`MEMBERSHIPS:
`
`American Society for Experimental Pathology
`American Society for Experimental Pathology
`Society for Developmental Biology
`Society for Developmental Biology
`Society for Experimental Biology and Medicine
`Society for Experimental Biology and Medicine
`American Association of University Professors
`American Association of University Professors
`International Association for Cardiac Biological Implants
`International Association for Cardiac Biological Implants
`American Association for Laboratory Animal Science
`American Association for Laboratory Animal Science
`The Wound Healing Society
`The Wound Healing Society
`Czechoslovak Society of Arts and Sciences
`Czechoslovak Society of Arts and Sciences
`
`HONORS:
`HONORS:
`
`1977 -
`1977 -
`
`1969 -
`1969 -
`
`1968 -
`1968 -
`
`1966 -
`1966 -
`
`Invited Speaker, Nobel Symposium,
`Invited Speaker, Nobel Symposium,
`"Biochemistry of Silicon and Related Problems"
`"Biochemistry of Silicon and Related Problems"
`Stockholm, Sweden
`Stockholm, Sweden
`Winner Concorso Internationale por la
`Winner Concorso Internationale por la
`Preventione de la Silicosi, Rome, Italy
`Preventione de la Silicosi, Rome, Italy
`National Science Council Award for Studies on Biochemistry of
`National Science Council Award for Studies on Biochemistry of
`Fibroblasts
`Fibroblasts
`State prize with the title Laureate of State for the contribution to
`State prize with the title Laureate of State for the contribution to
`connective tissue research
`connective tissue research
`
`CONSULTANTSHIPS:
`CONSULTANTSHIPS:
`1980 - present Kendall Healthcare Products, Inc., Mansfield, Massachusetts
`1980 - present Kendall Healthcare Products, Inc., Mansfield, Massachusetts
`
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`

`1980 - present
`1980 - present
`1982 - present
`1982 - present
`1982 -present
`1982 -present
`1987- present
`1987- present
`1987 - present
`1987 - present
`1988 - present
`1988 - present
`1988 - present
`1988 - present
`1988 - present
`1988 - present
`1988 - present
`1988 - present
`- 1989
`- 1989
`
`1987 - 1988
`1987 - 1988
`1982 - 1984
`1982 - 1984
`1982 -1986
`1982 -1986
`
`Meadox Medicals, Inc.
`Meadox Medicals, Inc.
`BioPlex (Datascope Corporation), New Jersey and California
`BioPlex (Datascope Corporation), New Jersey and California
`Meadox Medical Corporation, New Jersey
`Meadox Medical Corporation, New Jersey
`Amgen, Thousand Oaks, CA
`Amgen, Thousand Oaks, CA
`Universidad Federal DoCeara, Fortaleza, Brazil
`Universidad Federal DoCeara, Fortaleza, Brazil
`Angio-Medical Corp., Allston, MA
`Angio -Medical Corp., Allston, MA
`HealX, Duxbury, MA
`HealX, Duxbury, MA
`Molnlycke AB, Hospital Products Division, Molnlycke, Sweden
`Mölnlycke AB, Hospital Products Division, Mölnlycke, Sweden
`Research Corporation Technologies, Tucson, AZ
`Research Corporation Technologies, Tucson, AZ
`Prodex, Inc., Princeton, NJ
`Prodex, Inc., Princeton, NJ
`Serono Laboratories, Inc., Randolph, MA
`Serono Laboratories, Inc. , Randolph, MA
`A.J.N. Collagen Forschungs-und Vertriebs GmbH, West
`- 1989
`A.J.N. Collagen Forschungs -und Vertriebs GmbH, West
`1989
`Germany
`Germany
`Dornier Medizintechnik GmbH, West Germany
`Dornier Medizintechnik GmbH, West Germany
`Oceanic Institute, Hawaii
`Oceanic Institute, Hawaii
`Calcitek, Inc., California
`Calcitek, Inc., California
`
`CONSULTANTSHIPS (cont):
`CONSULTANTSHIPS (cont):
`
`1980 - 1984
`1980 - 1984
`
`1980 - 1983
`1980 - 1983
`1980 -
`1980 -
`
`- 1988
`- 1988
`
`1980 -
`1980 -
`1978 -
`1978 -
`
`1978 -
`1978 -
`1975 -
`1975 -
`1973 -
`1973 -
`1972 -
`1972 -
`1978 -
`1978 -
`1975 -
`1975 -
`1973 -
`1973 -
`1972 -
`1972 -
`1971 -
`1971 -
`1971 -
`1971 -
`
`General Motors Corporation Research Laboratories, Biomedical
`General Motors Corporation Research Laboratories, Biomedical
`Science Department, Detroit, Michigan
`Science Department, Detroit, Michigan
`United Nations Food and Agriculture Organization Madras, India
`United Nations Food and Agriculture Organization Madras, India
`Johnson and Johnson Products, New Brunswick, New Jersey
`Johnson and Johnson Products, New Brunswick, New Jersey
`Estee Lauder, Melville, NJ
`Estee Lauder, Melville, NJ
`Smith Kline, Philadelphia, Pennsylvania
`Smith Kline, Philadelphia, Pennsylvania
`International Fertility Research Program
`International Fertility Research Program
`Research Triangle Park, North Carolina
`Research Triangle Park, North Carolina
`Pfizer Pharmaceutical Co., New York
`Pfizer Pharmaceutical Co., New York
`Pathology Study Section A, NIH ,Bethesda, Maryland
`Pathology Study Section A, NIH,Bethesda, Maryland
`Edwards Laboratories, Santa Ana, California
`Edwards Laboratories, Santa Ana, California
`Alcon, Inc., Fort Worth, Texas
`Alcon, Inc., Fort Worth, Texas
`Pfizer Pharmaceutical Co., New Y ork
`Pfizer Pharmaceutical Co., New York
`Pathology Study Section A, NIH ,Bethesda, Maryland
`Pathology Study Section A, NIH,Bethesda, Maryland
`Edwards Laboratories, Santa Ana, California
`Edwards Laboratories, Santa Ana, California
`Alcon, Inc., Fort Worth, Texas
`Alcon, Inc., Fort Worth, Texas
`Respiratory Diseases Task Force, National Heart and Lung Institute
`Respiratory Diseases Task Force, National Heart and Lung Institute
`Biological Concepts, Inc., New York
`Biological Concepts, Inc. , New York
`
`NATIONAL/INTERNATIONAL SYMPOSIA:
`NATIONAL /INTERNATIONAL SYMPOSIA:
`
`Invited Speaker, Nobel Symposium "Biochemistry of Silicon and Related Problems"
`Invited Speaker, Nobel Symposium "Biochemistry of Silicon and Related Problems"
`Stockholm, Sweden, August 1977
`Stockholm, Sweden, August 1977
`
`Invited Speaker, IX World Congress on Fertility and Sterility, Miami, Florida, April 1977
`Invited Speaker, IX World Congress on Fertility and Sterility, Miami, Florida, April 1977
`
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`

`

`Participant, The Ciba Foundation: Oxygen Free Radicals and Tissue Damage, London,
`Participant, The Ciba Foundation: Oxygen Free Radicals and Tissue Damage, London,
`England, June 1978
`England, June 1978
`
`Main Speaker, International Symposium on Biology of Collagen, 50th Anniversary,
`Main Speaker, International Symposium on Biology of Collagen, 50th Anniversary,
`University of Aarhus, Aarhus, Denmark, August 1978
`University of Aarhus, Aarhus, Denmark, August 1978
`
`Invited Speaker, International Conference on Lung, Physiology and Pathology, Mexico
`Invited Speaker, International Conference on Lung, Physiology and Pathology, Mexico
`City, Mexico, March 1979
`City, Mexico, March 1979
`
`Invited Speaker, International Workshop on Vaginal, Contraception, Guatemala City,
`Invited Speaker, International Workshop on Vaginal, Contraception, Guatemala City,
`Guatemala , April 1979
`Guatemala , April 1979
`
`Invited Speaker, International Conference on Fibrous, Proteins: Scientific, Industrial and
`Invited Speaker, International Conference on Fibrous, Proteins: Scientific, Industrial and
`Medical Aspects: Massey University, Palmerston North, New Zealand, February 1979
`Medical Aspects: Massey University, Palmerston North, New Zealand, February 1979
`
`Chairman, New Developments in the Clinical Use of Skin Staplers Symposium in San
`Chairman, New Developments in the Clinical Use of Skin Staplers Symposium in San
`Diego, California, sponsored by the University of Arizona, September 21-22, 1984.
`Diego, California, sponsored by the University of Arizona, September 21 -22, 1984.
`
`Symposium on Basic and Clinical Aspects of Wound Contraction, Irving, TX June 6-8,
`Symposium on Basic and Clinical Aspects of Wound Contraction, Irving, TX June 6 -8,
`1987.
`1987.
`
`Twenty-Third Annual Meeting of the American College of Veterinary Surgeons, Invited
`Twenty -Third Annual Meeting of the American College of Veterinary Surgeons, Invited
`speaker: "Wound Healing Models in Laboratory Animals" February 3-5, 1988, Tucson,
`speaker: "Wound Healing Models in Laboratory Animals" February 3 -5, 1988, Tucson,
`AZ.
`AZ.
`
`Sixth International Symposium "Advances in Criciate Ligament Reconstruction of the
`Sixth International Symposium "Advances in Criciate Ligament Reconstruction of the
`Knee: Autogenous vs. Prosthetic., Century City Los Angeles, CA March 3-5, 1989
`Knee: Autogenous vs. Prosthetic., Century City Los Angeles, CA March 3 -5, 1989
`
`Seventh Charles River International Symposium "Animal Models: Swine in Biomedical
`Seventh Charles River International Symposium "Animal Models: Swine in Biomedical
`Research" Danvers, MA, September 18-20, 1989.
`Research" Danvers, MA, September 18 -20, 1989.
`1990 FASEB Annual Meeting "Effects of Malondialdehyde (MDA) on Rat Tail Tendon in
`1990 FASEB Annual Meeting "Effects of Malondialdehyde (MDA) on Rat Tail Tendon in
`vitro" Washington DC, April 2-5, 1990.
`vitro" Washington DC, April 2-5, 1990.
`XXVI Congress of the European Society for Surgical Research (ESSR) and VII. Tripartite
`XXVI Congress of the European Society for Surgical Research (ESSR) and VII. Tripartite
`Meeting with the Society of University Surgeons (SUS) and the Surgical Research Society
`Meeting with the Society of University Surgeons (SUS) and the Surgical Research Society
`(SRS), "New Method of Rapid Endothelization of ePTFE grafts Covered with Autologous
`(SRS), "New Method of Rapid Endothelization of ePTFE grafts Covered with Autologous
`Vein" Salzburg, Germany, May 8-11, 1991.
`Vein" Salzburg, Germany, May 8 -11, 1991.
`1990 FASEB Annual Meeting "Effects of Malondialdehyde (MDA) on Rat Tail Tendon in
`1990 FASEB Annual Meeting "Effects of Malondialdehyde (MDA) on Rat Tail Tendon in
`vitro" Washington DC, April 21-25, 1991.
`vitro" Washington DC, April 21 -25, 1991.
`
`COMMITTEES:
`COMMITTEES:
`
`Member, Department of Surgery Promotion and Tenure
`Member, Department of Surgery Promotion and Tenure
`University of Arizona, Tucson, Arizona
`University of Arizona, Tucson, Arizona
`Chairman, Department of Surgery Space Committee
`Chairman, Department of Surgery Space Committee
`University of Arizona, Tucson, Arizona
`University of Arizona, Tucson, Arizona
`
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`Chairman, Department of Surgery Human Subjects
`Chairman, Department of Surgery Human Subjects
`University of Arizona, Tucson, Arizona
`University of Arizona, Tucson, Arizona
`Member and Advisor: numerous M . S . and Ph. D .
`Member and Advisor: numerous M.S. and Ph.D.
`candidate committees in the Departments of
`candidate committees in the Departments of
`Microbiology-Medicine and campus, Agriculture-
`Microbiology- Medicine and campus, Agriculture -
`Nutrition, Environmental Research, Anatomy and
`Nutrition, Environmental Research, Anatomy and
`Cancer Center, University of Arizona, Tucson, Arizona
`Cancer Center, University of Arizona, Tucson, Arizona
`Member, University of Arizona Human Subjects Committee
`Member, University of Arizona Human Subjects Committee
`
`PUBLISHED CONTRIBUTIONS:
`PUBLISHED CONTRIBUTIONS:
`Editorial Boards:
`Editorial Boards:
`
`Journal of Bioengineering
`Journal of Bioengineering
`Connective Tissue Research
`Connective Tissue Research
`Journal of Investigative Dermatology
`Journal of Investigative Dermatology
`Life Sciences
`Life Sciences
`Pharmacology and Experimental Therapeutics
`Pharmacology and Experimental Therapeutics
`Scanning Microscopy International
`Scanning Microscopy International
`Society of Experimental Biology and Medicine
`Society of Experimental Biology and Medicine
`
`3 monographs written
`in English
`3 monographs written in English
`109 articles in Czech and Slovak languages
`109 articles in Czech and Slovak languages
`More than 380 articles published in Congress languages
`More than 380 articles published in Congress languages
`
`MAJOR RESEARCH INTERESTS:
`MAJOR RESEARCH INTERESTS:
`Pharmacology of Fibrosis
`Pharmacology of Fibrosis
`Mechanism of Tissue Injury
`Mechanism of Tissue Injury
`Biology of Zinc and Divalent Cations
`Biology of Zinc and Divalent Cations
`Collagen Medical Products
`Collagen Medical Products
`Contraceptive Methodology
`Contraceptive Methodology
`Nutrition, Aging
`Nutrition, Aging
`Wound Management
`Wound Management
`Articular Cartilage Ligament and Tendon Substitue and Repair
`Articular Cartilage Ligament and Tendon Substitue and Repair
`Vascular
`prostheses
`Vascular
`prostheses
`
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`Page 1
`Page 1
`
`Milos Chvapil, M.D., Ph.D., D. Sc.
`Milos Chvapil, M.D., Ph.D., D.Sc.
`Division of Surgical Biology, Department of Surgery
`Division of Surgical Biology, Department of Surgery
`University of Arizona Health Sciences Center
`University of Arizona Health Sciences Center
`Tucson, Arizona 85724
`Tucson, Arizona 85724
`List of Publications in Congress Languages
`List of Publications in Congress Languages
`
`Chvapil, M. DIE EIWEISSTOFFE IM NORMALEN LUNGENGEWEBE. I. EINFLUSS
`1.
`Chvapil, M. DIE EIWEISSTOFFE IM NORMALEN LUNGENGEWEBE. I. EINFLUSS
`1.
`DES ALTERNS. Physiologia Bohemoslovenica 4: 303-307, 1955.
`DES ALTERNS. Physiologia Bohemoslovenica 4: 303 -307, 1955.
`Chvapil, M., Budinsky, J. and Kouba, K.
`2.
`STUDIES IN FIBROPLASIA. 11.
`J. and Kouba, K.
`Chvapil, M., Budinsky,
`STUDIES IN FIBROPLASIA.
`II.
`2.
`CONNECTIVE TISSUE IN NORMAL AND FIBROMYOMATOUS HUMAN UTERUS. Cs.
`gynekol. 2: 334, 1956. (In Czech with English summary)
`CONNECTIVE TISSUE IN NORMAL AND FIBROMYOMATOUS HUMAN UTERUS. Cs.
`gynekol. 21: 334, 1956. (In Czech with English summary)
`Chvapil, M. A STUDY OF FIBROPLASIA. 111. HYDROXYPROLINE CONTENT OF
`3.
`Chvapil, M. A STUDY OF FIBROPLASIA. III. HYDROXYPROLINE CONTENT OF
`3.
`SCLEROPROTEINS IN THE LUNGS OF RATS DURING ONTOGENY.
`Physiologia
`SCLEROPROTEINS IN THE LUNGS OF RATS DURING ONTOGENY.
`Physiologia
`Bohemoslovenica 5: 421-427, 1956.
`Bohemoslovenica 5: 421 -427, 1956.
`
`Chvapil, M. STUDIES IN FIBROPLASIA. IV. SCLEROPROTEINS IN THE LUNGS,
`4.
`Chvapil, M. STUDIES IN FIBROPLASIA. IV. SCLEROPROTEINS IN THE LUNGS,
`4.
`LIVER, KIDNEYS AND MYOCARDIUM DURING ONTOGENY IN RATS.
`Physiologia
`LIVER, KIDNEYS AND MYOCARDIUM DURING ONTOGENY IN RATS.
`Physiologia
`Bohemoslovenica 6: 102-1 10, 1957.
`Bohemoslovenica 6: 102 -110, 1957.
`
`INFLUENCE OF
`Chvapil, M. and Hruza, Z. STUDIES IN FIBROPLASIA. VI.
`5.
`Chvapil, M. and Hruza, Z.
`STUDIES IN FIBROPLASIA. VI.
`INFLUENCE OF
`5.
`UNDERFEEDING AND DIETS WITH A VARYING PROTEIN CONTENT ON THE
`UNDERFEEDING AND DIETS WITH A VARYING PROTEIN CONTENT ON THE
`AMOUNT
`OF ORGAN SCLEROPROTEINS IN RATS UNDER CONDITIONS OF
`OF ORGAN SCLEROPROTEINS IN RATS UNDER CONDITIONS OF
`AMOUNT
`PHYSIOLOGICAL FIBROPLASIA. Physiologia Bohemoslovenica 6: 3 16-324, 1957.
`PHYSIOLOGICAL FIBROPLASIA. Physiologia Bohemoslovenica 6: 316 -324, 1957.
`Chvapil, M. DER EINFLUSS VON UNTERERNAHRUNG SOWIE VON DIATEN
`6.
`Chvapil, M. DER EINFLUSS VON UNTERERNAHRUNG SOWIE VON DIATEN
`6.
`VERSCHIEDNER ZUSAMMENSETZUNG AUF DIE IN DER RATTENLUNGE UND LEBER
`VERSCHIEDNER ZUSAMMENSETZUNG AUF DIE IN DER RATTENLUNGE UND LEBER
`ENTHALTENE MENGE VON SKLEROPROTEINEN BE1 EXPERIMENTELLER SILIKOSE.
`ENTHALTENE MENGE VON SKLEROPROTEINEN BEI EXPERIMENTELLER SILIKOSE.
`Archiv fbr Gewerbepathologie und Gewerbehygiene 15j: 377, 1957.
`Archiv für Gewerbepathologie Und Gewerbehygiene 15 : 377, 1957.
`11.
`Chvapil, M. and Zahradnik, R. NITROSAMINE SEKUNDARER AMINE.
`7.
`Chvapil, M. and Zahradnik, R.
`NITROSAMINE SEKUNDARER AMINE.
`7.
`II.
`MITTEIL. EINE POLAROGRAPHISCHE METHODE ZUR BESTIMMUNG VON PROLIN
`MITTEIL. EINE POLAROGRAPHISCHE METHODE ZUR BESTIMMUNG VON PROLIN
`Hoppe-Seyler 's Ztschr. f.
`UND HYDROXYPROLIN IN PROTEINHYDROLYSATEN.
`UND HYDROXYPROLIN IN PROTEINHYDROLYSATEN.
`Hoppe -Seyler's Ztschr.
`f.
`physiolog. Chemie. 307: 217-225, 1957.
`physiolog. Chemie. 307: 217 -225, 1957.
`8.
`Chvapil, M. and Zahradnik, R. STUDIES IN FIBROPLASIA. VIII. CHANGES IN
`Chvapil, M. and Zahradnik, R. STUDIES IN FIBROPLASIA. VIII. CHANGES IN
`8.
`THE RATE OF HYDROLYSIS OF CONNECTIVE TISSUE PROTEINS DURING AGING.
`THE RATE OF HYDROLYSIS OF CONNECTIVE TISSUE PROTEINS DURING AGING.
`Physiologia Bohemoslovenica 7: 227-233, 1958.
`Physiologia Bohemoslovenica 7: 227 -233, 1958.
`9. Kobrle, V. and Chvapil, M. VERANDERUNGEN VON KOLLAGENEIWEISSTOFFEN
`Kobrle, V. and Chvapil, M. VERANDERUNGEN VON KOLLAGENEIWEISSTOFFEN
`9.
`IM VERLAUFE DES ALTERNS UND BE1 DER EXPERIMENTELLEN SILIKOSE. Archiv
`IM VERLAUFE DES ALTERNS UND BEI DER EXPERIMENTELLEN SILIKOSE. Archiv
`fiir Gewerbepathologie und Gewerbehygiene 16-:
`526-538, 1958.
`für Gewerbepathologie ünd Gewerbehygiene 16 : 526 -538, 1958.
`
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`Page 2
`Page 2
`
`10. Chvapil, M. CHANGES IN FREE AND BOUND HYDROXYPROLINE DURING THE
`Chvapil, M. CHANGES IN FREE AND BOUND HYDROXYPROLINE DURING THE
`10.
`DEVELOPMENT OF NORMAL AND CORTISONE-TREATED CHICK EMBRYOS.
`DEVELOPMENT OF NORMAL AND CORTISONE -TREATED CHICK EMBRYOS.
`Physiologia Bohemoslovenica 8 : 186-194, 1959.
`Physiologia Bohemoslovenica 8: 186 -194, 1959.
`11. Chvapil, M. STUDIES IN FIBROPLASIA. IX. NOTES ON THE MECHANISM OF
`Chvapil, M. STUDIES IN FIBROPLASIA. IX. NOTES ON THE MECHANISM OF
`11.
`Physiologia Bohemoslovenica 2: 39 1 -
`THE EFFECT OF CORTISONE ON FIBROGENESIS.
`THE EFFECT OF CORTISONE ON FIBROGENESIS. Physiologia Bohemoslovenica 7: 391-
`398. 1958.
`398, 1958.
`Chvapil, M. and Hurych, J. HYDROXYLATION OF PROLINE IN VITRO. Nature 184:
`12.
`Chvapil, M. and Hurych, J. HYDROXYLATION OF PROLINE IN VITRO. Nature 184:
`12.
`1145, 1959.
`1145, 1959.
`13. Chvapil, M. and Hruza, Z. THE INFLUENCE OF AGING AND UNDERNUTRITION
`Chvapil, M. and Hruza, Z. THE INFLUENCE OF AGING AND UNDERNUTRITION
`13.
`ON CHEMICAL CONTRACTILITY AND RELAXATION OF COLLAGEN FIBRES IN RATS.
`ON CHEMICAL CONTRACTILITY AND RELAXATION OF COLLAGEN FIBRES IN RATS.
`Gerontologia 3: 241-252, 1959.
`Gerontologia 3: 241 -252, 1959.
`
`14. Chvapil, M. BIOCHEMICAL STUDY OF SCLEROPROTEINS OF LUNGS IN RATS
`Chvapil, M. BIOCHEMICAL STUDY OF SCLEROPROTEINS OF LUNGS IN RATS
`14.
`WITH EXPERIMENTAL SILICOSIS. Trudy simpoziuma PO probleme pnevmokoniozov Medgiz
`WITH EXPERIMENTAL SILICOSIS. Trudy simpoziuma po probleme pnevmokoniozov Medgiz
`1959, Moskva, p. 52 (in Russian).
`1959, Moskva, p. 52 (in Russian).
`NOTES ON LIVER PROTEIN
`15. Holeckova, E., Chytil, F. and Chvapil, M.
`NOTES ON LIVER PROTEIN
`Holeckova, E., Chytil, F.
`and Chvapil, M.
`15.
`Physiologia Bohemoslovenica 8:
`METABOLISM IN INTERMITTENTLY STARVED RATS.
`METABOLISM IN INTERMITTENTLY STARVED RATS. Physiologia Bohemoslovenica 8:
`400-404, 1959.
`400 -404,1959.
`16. Chvapil, M. and Holeckova, E. THE EFFECT OF DIFFERENT CONCENTRATIONS
`Chvapil, M. and Holeckova, E. THE EFFECT OF DIFFERENT CONCENTRATIONS
`16.
`OF SILICIC ACID AND SILICA DUST ON THE BIOSYNTHESIS OF COLLAGEN IN TISSUE
`OF SILICIC ACID AND SILICA DUST ON THE BIOSYNTHESIS OF COLLAGEN IN TISSUE
`CULTURES. British Journal of Industrial Medicine 16: 286-289, 1959.
`CULTURES. British Journal of Industrial Medicine 16: 286 -289, 1959.
`17. Chvapil, M. and Zahradnik, R. A STUDY OF THE CHEMICAL SHRINKAGE AND
`Chvapil, M. and Zahradnik, R. A STUDY OF THE CHEMICAL SHRINKAGE AND
`17.
`RELAXATION OF COLLAGEN FIBERS. Biochimica et Biophysica Acta 40: 329-339, 1960.
`RELAXATION OF COLLAGEN FIBERS. Biochimica et Biophysica Acta 40: 329 -339, 1960.
`18. Chvapil, M. MOGLICHKEITEN EINER QUANTITATIVEN BESTIMMUNG DES
`Chvapil, M. MÖGLICHKEITEN EINER QUANTITATIVEN BESTIMMUNG DES
`18.
`FIBROSEGRADES BE1 DER UNTERSUCHUNG EXPERIMENTELLER SILIKOSE. Beitrage
`FIBROSEGRADES BEI DER UNTERSUCHUNG EXPERIMENTELLER SILIKOSE. Beiträge
`zur Silikose-Forschung 64: 71, 1960.
`zur Silikose- Forschung 64: 71, 1960.
`19. Chvapil, M. and Cmuchalova, B. BIOLOGICAL SIGNIFICANCE OF PEPTIDE
`Chvapil, M. and Cmuchalova, B.
`BIOLOGICAL SIGNIFICANCE OF PEPTIDE
`19.
`CONTAINING HYDROXYPROLINE DURING THE DEVELOPMENT OF CARRAGEENIN
`CONTAINING HYDROXYPROLINE DURING THE DEVELOPMENT OF CARRAGEENIN
`GRANULOMA. Nature 186: 806, 1960.
`GRANULOMA. Nature 186: 806, 1960.
`20. Vyskocil, J., Sklensky, B., Chvapil, M. and Polak, B. DER EINFLUSS VON
`Vyskocil, J., Sklensky, B., Chvapil, M. and Polak, B. DER EINFLUSS VON
`20.
`AEROSOLINHALATIONEN AUF DIE DURCH GEMISCHTEN KOHLEN- UND
`AEROSOLINHALATIONEN AUF DIE DURCH GEMISCHTEN KOHLEN- UND
`QUARZSTAUB VERURSACHTE STAUBLUNGE BE1 RATTEN.
`Archiv
`fiir
`QUARZSTAUB VERURSACHTE
`BEI
`STAUBLUNGE
`RATTEN.
`Archiv
`für
`Gewerbepathologie und Gewerbehygiene 17: 627-642, 1960.
`Gewerbepathologie und Gewerbehygiene 17: 627 -642, 1960.
`
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`Page 3
`Page 3
`
`BIOCHEMICAL METHODS IN ASSESSING THE EFFECT OF
`Chvapil, M.
`21.
`BIOCHEMICAL METHODS IN ASSESSING THE EFFECT OF
`21.
`Chvapil, M.
`INDUSTRIAL DUST ON THE ORGANISM. Gigiena truda i prof. zabol. 4: 33-38, 1960 (in
`INDUSTRIAL DUST ON THE ORGANISM. Gigiena truda i prof. zabol. 4: 33 -38, 1960 (in
`Russian).
`Russian).
`
`22.
`Zahradnik, R. and Chvapil, M. STUDY OF THE RELATIONSHIP BETWEEN THE
`Zahradnik, R. and Chvapil, M. STUDY OF THE RELATIONSHIP BETWEEN THE
`22.
`MAGNITUDE OF BIOLOGICAL ACTIVITY AND THE STRUCTURE OF ALIPHATIC
`MAGNITUDE OF BIOLOGICAL ACTIVITY AND THE STRUCTURE OF ALIPHATIC
`COMPOUNDS. Experientia 16: 511, 1960.
`COMPOUNDS. Experientia 16: 511, 1960.
`
`ISOLATION OF PEPTIDES CONTAINING
`23. Kobrle, V. and Chvapil, M.
`ISOLATION OF PEPTIDES CONTAINING
`Kobrle, V.
`and Chvapil, M.
`23.
`HYDROXYPROLINE FROM ANIMAL TISSUES. Nature 190: 909, 1961.
`HYDROXYPROLINE FROM ANIMAL TISSUES. Nature 190: 909, 1961.
`ADAPTATION TO
`24. Hruza, Z., Fabry, P., Chvapil, M. and Holeckova, E.
`Hruza, Z., Fabry, P., Chvapil, M. and Holeckova, E.
`ADAPTATION TO
`24.
`UNDERNUTRITION AND TRAUMA AND INFLUENCE OF UNDERNUTRITION ON
`UNDERNUTRITION AND TRAUMA AND INFLUENCE OF UNDERNUTRITION ON
`BIOLOGICAL AGE. Aging Around the World, Columbia University Press, 1961.
`BIOLOGICAL AGE. Aging Around the World, Columbia University Press, 1961.
`
`25.
`Chvapil, M. and Kobrle, V. CHANGES IN PROLINE AND HYDROXYPROLINE IN
`Chvapil, M. and Kobrle, V. CHANGES IN PROLINE AND HYDROXYPROLINE IN
`25.
`COLLAGENS DURING THE DEVELOPMENT OF RATS. Experientia 17: 226-229, 1961.
`COLLAGENS DURING THE DEVELOPMENT OF RATS. Experientia 17: 226 -229, 1961.
`
`26. Hruza, Z., Chvapil, M. and Kobrle, V. THE EFFECT OF AGING AND CASTRATION
`Hruza, Z., Chvapil, M. and Kobrle, V. THE EFFECT OF AGING AND CASTRATION
`26.
`ON TENSILE STRENGTH, ELASTICITY AND SWELLING OF RAT COLLAGEN FIBERS.
`Physiologia Bohemoslovenica 20: 290-294, 196 1.
`ON TENSILE STRENGTH, ELASTICITY AND SWELLING OF RAT COLLAGEN FIBERS.
`Physiologia Bohemoslovenica 20: 290 -294, 1961.
`Chvapil, M. VERANDERUNGEN IN DER CHEMISCHEN ZUSAMMENESETZUNG
`27.
`Chvapil, M. VERANDERUNGEN IN DER CHEMISCHEN ZUSAMMENESETZUNG
`27.
`DER LUNGE WAHREND DER ENTWICKLUNG DER EXPERIMENTELLEN SILIKOSE.
`DER LUNGE WAHREND DER ENTWICKLUNG DER EXPERIMENTELLEN SILIKOSE.
`Archiv fir Gewerbepathologie iind Gewerbehygiene 18-:
`556-564, 1961.
`Archiv für Gewerbepathologie Und Gewerbehygiene 18 : 556 -564, 1961.
`
`Chvapil, M. and Cmuchalova, B. DYNAMICS OF CHANGES IN CONNECTIVE
`28.
`Chvapil, M. and Cmuchalova, B. DYNAMICS OF CHANGES IN CONNECTIVE
`28.
`TISSUE COMPONENTS DURING DEVELOPMENT OF CARRAGEENAN GRANULOMA.
`TISSUE COMPONENTS DURING DEVELOPMENT OF CARRAGEENAN GRANULOMA.
`Experimental Medicine and Surgery 19: 171-182, 1961.
`Experimental Medicine and Surgery 19: 171 -182, 1961.
`29. Kobrle, V. and Chvapil, M. CHANGES OF ULTRAFILTRABLE HYDROXYPROLINE
`Kobrle, V. and Chvapil, M. CHANGES OF ULTRAFILTRABLE HYDROXYPROLINE
`29.
`IN BLOOD SERUM DURING DEVELOPMENT OF CARRAGEENAN GRANULOMA AND
`IN BLOOD SERUM DURING DEVELOPMENT OF CARRAGEENAN GRANULOMA AND
`DURING AGING OF RATS AND GUINEA PIGS. Experientia 17: 519-522, 1961.
`DURING AGING OF RATS AND GUINEA PIGS. Experientia 17: 519 -522, 1961.
`
`30. Budinsky, J., Fantova, B. and Chvapil, M. KLINISCHE FOLGERUNGEN AUS DEN
`Budinsky, J., Fantova, B. and Chvapil, M. KLINISCHE FOLGERUNGEN AUS DEN
`30.
`FORSCHUNGSERGEBNISSEN UBER DIE BEEINFLUSSUNG DES BINDEGEWEBES IN
`FORSCHUNGSERGEBNISSEN UBER DIE BEEINFLUSSUNG DES BINDEGEWEBES IN
`GYNAEKOLOGIE UND GEBURTSHILFE.
`111. Weltkongress fir Gynakologie und
`GYNAEKOLOGIE UND GEBURTSHILFE.
`für Gynakologie und
`III. Weltkongress
`Geburtshilfe, Wien, 316, 1961.
`Geburtshilfe, Wien, 316, 1961.
`
`31. Hurych, J. and Chvapil, M. HYDROXYLATION OF PROLINE IN CELL-FREE
`Hurych, J. and Chvapil, M. HYDROXYLATION OF PROLINE IN CELL -FREE
`31.
`SYSTEMS ISOLATED FROM CARRAGEENAN GRANULOMA. Naturwissenschaften 9: 17-
`SYSTEMS ISOLATED FROM CARRAGEENAN GRANULOMA. Naturwissenschaften 49: 17-
`19, 1962.
`19, 1962.
`
`Chvapil, M., Holeckova, E., Cmuchalova, B., Kobrle, V. and Hurych, J.
`32.
`Chvapil, M., Holeckova, E., Cmuchalova, B., Kobrle, V.
`32.
`and Hurych,
`J.
`ULTRAFILTRABLE AND COLLAGEN-BOUND HYDROXYPROLINE IN CHICKEN LUNG
`ULTRAFILTRABLE AND COLLAGEN -BOUND HYDROXYPROLINE IN CHICKEN LUNG
`
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`Page 4
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`TISSUE CULTURES AND IN SUBCELLULAR FRACTIONS. Experimental Cell Research 26:
`TISSUE CULTURES AND IN SUBCELLULAR FRACTIONS. Experimental Cell Research 26:
`1-8,