I 1111111111111111 11111 1111111111 111111111111111 1111111111111111 IIII IIII IIII
`US009651533B2
`
`c12) United States Patent
`Islam
`
`(IO) Patent No.:
`(45) Date of Patent:
`
`US 9,651,533 B2
`*May 16, 2017
`
`(54) SHORT-WAVE INFRARED
`SUPER-CONTINUUM LASERS FOR
`DETECTING COUNTERFEIT OR ILLICIT
`DRUGS AND PHARMACEUTICAL PROCESS
`CONTROL
`
`(71) Applicant: OMNI MEDSCI, INC., Ann Arbor, MI
`(US)
`
`(72)
`
`Inventor: Mohammed N. Islam, Ann Arbor, MI
`(US)
`
`(73) Assignee: Omni Medsci, Inc., Ann Arbor, MI
`(US)
`
`( *) Notice:
`
`Subject to any disclaimer, the term ofthis
`patent is extended or adjusted under 35
`U.S.C. 154(b) by 0 days.
`
`This patent is subject to a terminal dis(cid:173)
`claimer.
`
`(21) Appl. No.: 14/875,709
`
`(22) Filed:
`
`Oct. 6, 2015
`
`(65)
`
`Prior Publication Data
`
`US 2016/0047787 Al
`
`Feb. 18, 2016
`
`Related U.S. Application Data
`
`(63) Continuation of application No. 14/108,986, filed on
`Dec. 17, 2013, now Pat. No. 9,164,032.
`(Continued)
`
`(51)
`
`Int. Cl.
`GOJJ 5120
`GOIN 33115
`
`(2006.01)
`(2006.01)
`(Continued)
`
`(52) U.S. Cl.
`CPC ........... GOIN 33115 (2013.01); A61B 510013
`(2013.01); A61B 510022 (2013.01);
`(Continued)
`
`(58) Field of Classification Search
`CPC ....... GOIN 33/15; GOIN 21/359; GOIN 33/49
`(Continued)
`
`(56)
`
`References Cited
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`U.S. PATENT DOCUMENTS
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`6/ 1979 Sakoe et al.
`(Continued)
`
`FOREIGN PATENT DOCUMENTS
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`CN
`DE
`
`7/2013
`101849821 B
`10/2010
`102010012987 Al
`(Continued)
`
`OTHER PUBLICATIONS
`
`Istepanian, Robert H., "The Comparative Performance of Mobile
`Telemedical Systems based on the IS-54 and GSM Cellular Tele(cid:173)
`phone Standards"; Journal of Telemedicine and Telecare 1999; pp.
`97-104.
`
`(Continued)
`
`Primary Examiner - David Porta
`Assistant Examiner - Abra Fein
`(74) Attorney, Agent, or Firm - Brooks Kushman P.C.
`
`ABSTRACT
`(57)
`A measurement system includes a wearable measurement
`device for measuring one or more physiological parameters,
`including a light source comprising a plurality of light
`emitting diodes (LEDs) configured to generate an output
`optical beam with a near-infrared wavelength between 700
`nanometers and 2500 nanometers. The light source is con(cid:173)
`figured to increase signal-to-noise ratio by increasing a light
`intensity and pulse rate of the LEDs. The system includes a
`plurality of lenses configured to receive the output optical
`beam and to deliver an analysis output beam to a sample.
`The wearable measurement device includes a receiver con(cid:173)
`figured to process the analysis output beam reflected or
`transmitted from the sample and to generate an output signal
`(Continued)
`
`1802
`I
`CHOPPER
`~-~-~
`
`1801
`
`1803
`
`1804
`\
`POL
`
`SC SOURCE
`
`MONOCHROMATOR
`
`COMPUTER
`
`1811
`
`1800
`~
`
`1808
`
`SAMPLE DETECTOR+
`PRE·AMP (MCT)
`
`REFERENCE DETECTOR
`+ PRE-AMP (MCT)
`
`1809
`
`1806
`
`SAMPLE
`
`1807
`
`REFERENCE
`
`LOCK-IN AMP #1
`
`LOCK-IN AMP #2
`
`1810
`
`Petitioner Apple Inc. – Ex. 1001, p. 1
`
`

`

`US 9,651,533 B2
`Page 2
`
`that may be transmitted to a remote device configured to
`process the received output status to generate processed data
`and to store the processed data.
`
`18 Claims, 26 Drawing Sheets
`
`Related U.S. Application Data
`
`(60) Provisional application No. 61/747,487, filed on Dec.
`31, 2012.
`
`(51)
`
`(2006.01)
`(2006.01)
`(2006.01)
`(2006.01)
`(2006.01)
`(2014.01)
`(2006.01)
`(2006.01)
`(2006.01)
`(2006.01)
`(2006.01)
`
`Int. Cl.
`A61B 511455
`A61B 5100
`GOJJ 3/10
`GOJJ 3/28
`GOJJ 3/453
`GOIN 211359
`A61B 51145
`GOIN 33/49
`HOJS 3/30
`GOJJ 3/14
`GOJJ 3/18
`(52) U.S. Cl.
`CPC .......... A61B 510075 (2013.01); A61B 510086
`(2013.01); A61B 510088 (2013.01); A61B
`511455 (2013.01); A61B 5114532 (2013.01);
`A61B 5114546 (2013.01); A61B 514547
`(2013.01); GOJJ 3/108 (2013.01); GOJJ 3/28
`(2013.01); GOJJ 3/453 (2013.01); GOIN
`211359 (2013.01); GOIN 33/49 (2013.01);
`A61B 2562/0233 (2013.01); A61B 2562/0238
`(2013.01); A61B 2562/146 (2013.01); A61B
`2576/02 (2013.01); GOJJ 3/14 (2013.01);
`GOJJ 3/1838 (2013.01); GOJJ 2003/104
`(2013.01); GOJJ 2003/2826 (2013.01); GOIN
`2201/061 (2013.01); GOIN 2201/062
`(2013.01); GOIN 2201/12 (2013.01); HOJS
`3/302 (2013.01)
`
`(58) Field of Classification Search
`USPC ....................................................... 250/338.4
`See application file for complete search history.
`
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`Petitioner Apple Inc. – Ex. 1001, p. 2
`
`

`

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`Petitioner Apple Inc. – Ex. 1001, p. 3
`
`

`

`US 9,651,533 B2
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