12/14/2019
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`P.A.A.R.I. Law Enforcement Partners Hail Ease of Use of Adapt Pharma Single-Step Nasal Narcan - PAARI
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`You are here: Home / Blog / P.A.A.R.I. Law Enforcement Partners Hail Ease of Use of Adapt Pharma
`Single-Step Nasal Narcan
`
`June 12, 2017
`
`P.A.A.R.I. Law Enforcement Partners Hail Ease
`of Use of Adapt Pharma Single-Step Nasal
`Narcan
`The Police Assisted Addiction and Recovery Initiative and its law enforcement
`partners are praising Adapt Pharma on the ease of use of the company’s 4 mg
`single-step naloxone spray. Last July, Adapt Pharma donated 10,000 doses of
`the lifesaving overdose reversal drug to P.A.A.R.I. for distribution to its law
`enforcement partners.
`
`Two human factor studies recently conducted by Adapt indicated that, without
`instruction or training, a cross section of the population (adults and adolescents,
`normal and low literate) can complete the critical steps necessary to properly
`deploy NARCAN Nasal Spray in simulated emergency situations.
`
`According to law enforcement officers, the 4 mg single-step device is much
`easier to use other forms of naloxone, as it does not require assembly and only
`needs to be used in one nostril. Additionally, the double dose in Adapt’s 4 mg
`Narcan means that officers and community members are better able to reverse
`overdoses with the presence of fentanyl, which is especially prevalent now that
`first responders are at risk for accidental overdose when handling and
`processing fentanyl and fentanyl analogues.
`
`“Just the other day our officers responded to a 911 call for an opiate overdose.
`Upon arrival officers found the sister of the victim fumbling with an outdated
`multi-step Narcan device. She was unsuccessful at installing the atomizer to
`enable the delivery of the lifesaving dose of Narcan. Fortunately, our officers
`were nearby and equipped with the one-step dose of 4 mg Narcan that we
`received from P.A.A.R.I. through the generous donation from Adapt Pharma.
`That dose saved the patient’s life. Following the transport of the patient to a
`nearby hospital, the Arlington Police Officer remained on scene for about an
`hour and dispensed a new 4 mg Narcan kit and trained the patient’s loved ones
`on how to use it. These lifesaving services are enable through the great work of
`P.A.A.R.I. and our partners at Adapt Pharma,” said Arlington Police Chief
`Frederick Ryan, who also chairs P.A.A.R.I.’s Police Council.
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`https://paariusa.org/2017/06/12/p-r-law-enforcement-partners-hail-ease-use-adapt-pharma-single-step-nasal-narcan/
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`1/4
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`Opiant Exhibit 2145
`Nalox-1 Pharmaceuticals, LLC v. Opiant Pharmaceuticals, Inc.
`IPR2019-00694
`Page 1
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`12/14/2019
`P.A.A.R.I. Law Enforcement Partners Hail Ease of Use of Adapt Pharma Single-Step Nasal Narcan - PAARI
`The single-step Narcan device from Adapt Pharma is quickly becoming the
`device of choice for law enforcement. According to some of P.A.A.R.I.’s partners:
`
`Melrose, Mass.
`“The Melrose Police Department will soon be changing over from the 2 mg multi-
`piece dose to the 4 mg single-step nasal naloxone. I have been trained in both
`delivery systems and without a doubt the easier of the two is the 4 mg single-
`step nasal naloxone. The boxes of the 2 mg doses fall apart, the atomizers come
`separate, and they are half the strength of the 4 mg product. The 4 mg single-
`step nasal naloxone comes well packaged, with little chance of damaging the
`product, contrary to the 2 mg doses that have been damaged and had to be
`thrown away. The simplicity of the 4 mg single-step nasal naloxone deployment
`is almost fool proof. Without a doubt, this product is a giant step forward and we
`will be happy to utilize it in the future,” said Melrose Police Sgt. Dave Mackey.
`
`Wise County, Va.
`“The Wise County Sheriff’s Office implemented the naloxone program January
`2017. I became an instructor for the Virginia Department of Behavioral Health
`who sponsored the REVIVE Naloxone program. I have had the opportunity to
`train more than 150 LEO and Community leaders. Adapt Pharma through
`P.A.A.R.I. provided our agency with enough naloxone that every Deputy now
`carries the 4 mg nasal Narcan. As an instructor and LEO, I feel that the simplicity
`of the nasal Narcan by far is the best product for our agency. Time is of the
`essence in an overdose case and deputies arriving on scene don’t have to think
`about assembling anything. I have also been working to educate our community
`about the problems we face through a recent seminar entitled “Taking Our
`Communities Back” Synthetic & Opioid Abuse Education. We are planning to
`train community leaders to support those individuals who are addicted to opioids.
`I feel that the nasal Narcan is the best choice for our community. We have not
`yet had to administer naloxone but we are ready when that day comes thanks to
`the generosity of Adapt Pharma and the support of P.A.A.R.I.,” said Sgt. Teresa
`A. Meade or the Wise County, Va. Sheriff’s Office.
`
`Olmstead Township, Ohio
`“The one-piece compact, pre-assembled, ready to use 4 mg Narcan spray units
`alleviate the need to perform fine motor skills under stressful conditions, which
`saves time and ultimately saves lives,” said Lt. Mark Adam of the Olmsted
`Township, Ohio Police Department.
`
`Middlebury, Vt.
`“Officers who have applied Narcan in the 4 mg single-step device have found
`this device to be simple and quick to use, durable, compact, and it eliminates
`potential points of failure. Training in its use is simple and is easily retained.
`Under adverse and stressful conditions, we’ve found its application to be quick
`and effective. Every officer is trained and carries multiple 4 mg units. They have
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`https://paariusa.org/2017/06/12/p-r-law-enforcement-partners-hail-ease-use-adapt-pharma-single-step-nasal-narcan/
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`2/4
`
`Opiant Exhibit 2145
`Nalox-1 Pharmaceuticals, LLC v. Opiant Pharmaceuticals, Inc.
`IPR2019-00694
`Page 2
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`12/14/2019
`P.A.A.R.I. Law Enforcement Partners Hail Ease of Use of Adapt Pharma Single-Step Nasal Narcan - PAARI
`also received advisories on the risk of inhalation/absorption of fentanyl and other
`opioid substances. Officers are aware they may need to apply Narcan to affected
`officers as well,” said Middlebury, Vt. Police Chief Tom Hanley.
`
`Gloucester, Mass.
`“The 4 mg nasal naloxone supplied to our department has worked very well. Due
`to its single step design it is faster and easier to use and delivers twice the
`dosage,” said Gloucester Police Chief John McCarthy.
`
`Lee County, Ill.
`“Anytime you are involved in a life-threatening crisis situation, time is of the
`essence. In addition, under stress, officers and deputies need the right tools for
`the job that are easy to use and efficient. This type of nasal naloxone is
`important for all those reasons and we much appreciate Adapt Pharma
`supporting our initiatives in this area. It will, and has, saved lives. I may even
`save the life of an officer or deputy who unknowingly comes in contact with an
`opiate or derivative,” said Lee County, Ill. Sheriff John Simonton.
`
`East Bridgewater, Mass.
`“Police officers are often the first to arrive at overdose scenes. The 4 mg single
`step Narcan is much easier to use and carry. Officers do not have to put
`anything together; the Narcan is removed from the package and administered.
`The stronger dose of Narcan is administered quickly and allows us to save more
`lives. It gives us a tool to combat Fentanyl and other dangerous drugs,” said
`East Bridgewater, Mass. Sgt. Bill Patterson. “Officers are not worried about a vial
`of Narcan breaking. The 4 mg Narcan can be worn on a duty belt. This gives
`responding officers immediate access to Narcan if they are accidentally exposed
`to Fentanyl.”
`
`Added P.A.A.R.I’s leaders:
`
`“Law enforcement, in coordination with health authorities, needs every available
`tool to save lives during this opioid epidemic. A simpler and, as needed, more
`powerful antidote to overdoses will save lives,” said P.A.A.R.I. Board Member Gil
`Kerlikowske.
`
`“We are proud to work with a company like Adapt Pharma, which is doing so
`much to combat the opioid crisis. Thanks to the ease of use and higher dosage
`of their nasal Narcan product, more lives will be saved from opioid overdose.
`This is important now more than ever as even more potent drugs such as
`fentanyl are becoming more widespread,” said P.A.A.R.I. Executive Director Allie
`Hunter McDade.
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`https://paariusa.org/2017/06/12/p-r-law-enforcement-partners-hail-ease-use-adapt-pharma-single-step-nasal-narcan/
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`3/4
`
`Opiant Exhibit 2145
`Nalox-1 Pharmaceuticals, LLC v. Opiant Pharmaceuticals, Inc.
`IPR2019-00694
`Page 3
`
`

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`12/14/2019
`P.A.A.R.I. Law Enforcement Partners Hail Ease of Use of Adapt Pharma Single-Step Nasal Narcan - PAARI
`“P.A.A.R.I. and our more than 260 police department partners cannot thank
`Adapt enough for providing 10,000 lifesaving doses of 4 mg Narcan to our first
`responders. There are only two options for addressing the opioid epidemic —
`long term treatment or death. Adapt’s generous donation has helped prevent
`death for thousands of people suffering from the disease of addiction while the
`healthcare system catches up and treats the disease of addiction like every
`other chronic illness,” said P.A.A.R.I. Co-founder and Chairman John Rosenthal.
`
`About NARCAN® (naloxone HCl) Nasal Spray
`NARCAN® Nasal Spray is indicated for the emergency treatment of known or
`suspected opioid overdose, as manifested by respiratory and/or central nervous
`system depression. NARCAN® Nasal Spray is intended for immediate
`administration as emergency therapy in settings where opioids may be present.
`NARCAN® Nasal Spray is not a substitute for emergency medical care.
`
`About Adapt Pharma
`Adapt Pharma is a privately-held pharmaceutical company committed to
`positively impacting the lives of patients. Adapt Pharma’s strategy is to identify,
`evaluate, selectively acquire and enhance the value of late stage development,
`and FDA approved, pharmaceutical products. Adapt Pharma’s company
`headquarters is in Dublin, Ireland and its U.S. headquarters is in Radnor,
`Pennsylvania. For more information, please visit www.adaptpharma.com.
`
`Article by John Guilfoil / Blog
`
`https://paariusa.org/2017/06/12/p-r-law-enforcement-partners-hail-ease-use-adapt-pharma-single-step-nasal-narcan/
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`4/4
`
`Opiant Exhibit 2145
`Nalox-1 Pharmaceuticals, LLC v. Opiant Pharmaceuticals, Inc.
`IPR2019-00694
`Page 4
`
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