NUVASIVE - EXHIBIT 2027
`Alphatec Holdings Inc. et al. v. NuVasive, Inc.
`IPR2019-00362
`
`

`

`The Buttenvorth Group
`United Kl
`lam
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`This book is sold subject to the Standard Conditions of
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`First published in 1961 by the Caxton Publishing Co Ltd
`as The British Medical Dictionary, edited by Sir Arthur
`Salusbury MacNalty.
`
`_
`_
`‘
`Revised Edition 1963
`RewndEl’idiitgo: l19279685 asfiutterworths Medical Dictionary
`Secs
`© Butterworth & 00 (Publishers) Ltd 1978
`
`ISBN 0 407 00061 S
`
`'
`
`British Library Cataloguing in Publication Data
`
`ISBN 0407-00061-5
`
`Butterworths medical dictionary—2nd ed.
`1. Medicine—Dictionaries
`I. MacNalty, Sir Arthnr Salusbury
`I. Critchley, Macdonald
`610’.3
`R125
`
`77—30154
`
`a \.
`
`Set in Times by computer assisted typesetting (CATplan)
`and printed by Billing & Sons Limited,»
`KGuildt‘ord, London and Worcester:
`
`

`

`This material may be protected by Copyright law (Title 17 US. Code) i
`
`logadoblennorrhoea
`
`logadoblennorrhoea (logad'o-blen'or‘e"ah). Conjunctival blen-
`norrhoea. [Gk logades whites of the eyes, blennorrhoea.]
`logagnosia (log'agno'se'ah). Alexia. [Gk logos word, agnosia.]
`logagraphia (log'a'graf'e'ah). Agraphia;
`inability to put
`into
`written words ideas present in the mind;
`loss of the writing
`power. [Gk logos word, agraphia.)
`logamnesia (log-am'nc'ze'ah). Auditory or visual aphasia; word
`deafness, word blindness. [Gk logos word, amnesia]
`logaphasia (log-af'a'ze-ah). Motor aphasia; generally caused by a
`cerebral lesion. [Gk logos word, aphasia]
`logasthenia (log‘as'the'ne‘ah). Impairment of the mental faculty
`which is concerned with understanding of the spoken word. [Gk
`logos word, asthenia.]
`logoclonia (log‘o-ldO'ne'ah). Irregular repetition of the last syllable
`of a word. [Gk logos word, klonein to agitate]
`logographic (logograf'ik). Relating to written words. [Gk logos
`word, graphein to record]
`loss of power
`logokophosis (log‘o‘ko'fo’sis). Auditory aphasia;
`of understanding what is said. [Gk logos word, lcophos deaf]
`it
`logomania (log‘o‘ma’ne'ah). 1. Garrulity so excessive that
`constitutes a form of mania;
`in many cases new words are
`invented to keep up the flow of talk. 2. Aphasia. [Gk logos word,
`mania]
`1. Any neurotic condition which
`logoneumsis (log'n'newr‘o’sis).
`is associated with a speech defect. 2. A neurotic condition
`associated with impaired mental
`faculties. [Gk logos word,
`neurosis]
`log'O'pe‘dix). That
`logopaedics (log‘o‘pe'de'ah,
`logopaedia,
`branch of medical science which is concerned with the general
`physiological and pathological aspect of the speech organs and
`with the study and correctionvof defects of speech. [Gk logos
`word, pals child]
`1. Any speech disorder which is caused
`logopathy (log'op'ath'e).
`by a central-nerve lesion. 2. Logoneurosis. [Gk logos word.
`pathos disease]
`logophasia (log'o‘fa'ze'ah). Loss of ability to articulate correctly.
`[Gk logos word, phasis utterance]
`logoplegia (log'c'ple'je'ah).
`1. Any type of paralysis which affects
`the organs of speech. 2. Failure to utter words although the latter
`are not actually forgotten; a defect of the mechanism of word
`‘ production. [Gk logos word, plege stroke]
`logorrhoea (log-O're'ah). Garrulity to an excessive degree. [Gk
`logos word, rhoia flow.]
`logospasm (log'O'spazm). A condition in which words are
`produced in spasms; speech tending to be of explosive type and
`stuttering in character. [Gk logos word, spasm.)
`logwood ,(108'wud).
`1. The tree Haematoxylon campechianum
`Linn. 2. Haematoxylum. [ME logge, wudu.]
`Lohmann, Karl (b. 1898). Berlin biochemist.
`Lohmann reaction. The high-energy transfer of a phosphate
`radical
`from adenosine triphosphate to creatine, or
`to
`adenosine diphosphate from creatine phosphate.
`loiasis (lo-ifas'is). The condition caused by infection with the
`helminth Loa 10a, conveyed by bites of flies of the genus
`Chrysops, and found especially in the Cameroons.
`loin [lumbus (NA)] (loin). That portion of the body on both
`sides of the spine which is between the false ribs and the upper
`plane of the pelvis; the flank. [OFL logne.)
`loliism,
`lolism (lo-le'izm,
`lo‘lizm). Poisoning by the seeds of
`Lolium temulentum which is said to contain an alkaloid,
`although it has also been stated that the toxicity is due to a
`fungus. Symptoms of vertigo, dizziness, headache, and impaired
`vision are produced.
`Lombard, Etienne (b. 1868). French physician.
`Lombud’s test. For simulated unilateral deafness: a Barany
`noise box is applied to the allegedly good car. The patient is
`asked to read aloud from a newspaper. The noise box is
`switched on. A patient with a severe degree of deafness in the
`opposite ear will immediately raise his voice and may even
`
`Iongitypical
`
`Lombardi, Antonio (fl. 1910). Naples physician.
`Lombardi’s sign. Dilated venules over the spines of the 7th
`cervical and first three dorsal vertebrae in early pulmonary
`tuberculosis.
`
`Lomholt, Svend (b. 1888). Copenhagen dermatologist.
`Lomholt’s ointment. Unguentum potassii polysulphidi.
`Finsen-Lomholt lamp. A lamp that emits ultraviolet rays of
`wavelength mainly from 3 300 to 3600 A (330-360 nm); the
`light rays are all filtered out and the heat rays absorbed. The
`ultraviolet rays constitute 75 per cent of the total, and the
`irradiation time is only one-third of that required with the
`Finsen lamp.
`Finsen—Lornholt treatment. Treatment of lupus vulgaris by
`filtered ultraviolet rays emanating from a Finsen-Lomholt
`lamp; obsolescent.
`lonchocarpus (long‘kokar’pus). Cube root, barbasco, timbo; the
`dried root of species of Lonehocarpus (family Leguminosae). It
`contains about 3 per cent of the insecticide, rotenone, and is used
`for the same purposes as derris root;
`it is also employed in
`scabies. [Gk lonche spear, lmrpos fruit]
`long-acting thyroid stimulator (LATS). An IgG immunoglo~
`bulin which binds to thyroid membranes at a site close to or
`identical with the TSH receptor. It is found in the serum of
`patients with Graves‘ disease and it, rather than TSH.
`is
`probably the cause of the hyperthyroidism in this condition.
`LATS absorbing activity (LAA). A neutralizing factor which is
`found in thyroid microsomes and cell sap. LATS protector
`(LATS P). An immunoglobulin found in the serum of hyper-
`thyroid, patients with Graves' disease. It inhibits the absorption
`of LATS by LAA (LATS absorbing activities) and can pass
`through the placenta and induce neonatal hyperthyroidism
`similar to that produced by LATS in hyperthyroid mothers. This
`new type of neonatal hyperthyroidism is associated with absence
`of LATS in the maternal serum.
`longevity (lon'jewit'e). Long life. [L Iongus long, aevum age]
`longilineal (lon‘je'lin'e'al). Referring to a slight and long type of
`bodily build. [L longus long, line]
`longimanous (lon‘je‘man'us). Having long, slender hands.
`longus long, menus hand]
`longing (longing). An eager desire or craving, very often for some
`unusual kind of food, or even for inedible material. as is often
`observed in pregnancy. Some form of abnormal longing may also
`be noted in persons who are neurotic or mentally unstable. [AS
`langr'an.)
`longipedate (lon'je‘ped‘ate). Having long, narrow feet. [L Iongus
`long. pcs foot]
`longissimus muscle [musculus longissimus (NA)] (lon'iis-im--
`us musl). A muscle which forms the intermediate column of the
`sacrospinalis muscle and is composed from below upwards of the
`longissimus thoracis,
`longissimus cervicis, and longissimus
`capitis muscles. [L, longest]
`longissimus capitis muscle [musculus longissimus capitis
`(NA)] (lon'jis'im'us kap'it’is musl). A part of the longissimus
`muscle attached to the skull. [L, longest of the head]
`longissimus cervicis muscle [musculus longissimus cervicis
`(NA)] (lon'jis'im’us serviS'is musl).
`,A part of the longissimus
`muscle attached to the cervical vertebrae. [L,
`longest of the
`neck.)
`longissimus thoracis muscle [musculus longissimus thoracis
`(NA)] (lon'jis'im'us flior‘as'is musl). One of the elements of the
`longissimus muscle mass which is inserted by two series of slips;
`medially into the transverse processes of the thoracic vertebrae
`and the transverse and accessory processes of
`the lumbar
`vertebrae, and laterally into the ribs. It is supplied by posterior
`rami of thoracic and lumbar nerves, and is an extensor of the
`spine. [L, longest of the thorax]
`longitudinal [longitudinalis (NA)] aon'je-terdin'al). Running
`lengthwise; in a direction parallel to the long axis of the body. [L
`
`[1.
`
`

`

`
`_._—.____.,
`m marmal mly n2 pmtaned by mum.» :w um. 17 u 5 Cece)
`._—__—_.___<
`
`meckeleetpmy
`
`, mediaetinum“
`
`
`
`meckelectomy:‘(mekelektome) Surgical eXcision of the;ephem-
`win Elthe middle;
`
`mesiel 2 An averageor centrevaiue of
`'
`éébbservatio’ns
`
`
`
`palatine (Meekel's) ganglion. [Meekel's ganglten, Gk ektdim a
`
`cutting <3'ut.]
`i
`.,
`_ “taken in orderirnm the lowest value to die highes
`
` mmis on appipwd
`Meelofenoxate (mekloienoxate) BP
`name for ldtmethylammoet'
`bra! stimulant
`
`,,
`
`
`
`capiil
`17 portal viins leading to tti
`
`sinus" d‘s‘ be mg the cells {if the i:
`
`edi
`axilla‘ ,y theunion of
`
`
` fora—(S6~dtmethylben21mrdttzol
`,
`from alltheroars oithe[bra ,
`in the treatment of vitami
`'
`
`mecoeephalie (me-
`
`
`kom‘eter) An instrument resembling a pair of
`aSeale attachment used
`, the detennmatmn of
`
`.
`013mm. {Gk mek‘anpoppy ,
`memnidine '(‘mekenidcan“; C2,,H3;
`
`
`meeonine (me11011 ,1
`princt‘le) found in
`
`
`tinal fibrosis, often as' G“
`a
`tinum, Gk .itis infla ,
`
`
`
`
`
`
`A pericardium assneiete‘d ’
`,_
`
`'
`'
`mecomum (In
`"
`pericardiumfli
`
`
`miner and w siding of bite, mucoidrdebrije
`
`
`
`, tinum, Gk Skopeinto ,_
`.,
`
`
`
`mediastinoseopy» medeas'tin'osfiik pe) Examination of
`the
`:
`' ediastinum through a small suprasterna’l incision by means of a
`
`bular instrument fitted with a system of lenses and a terminal ,
`
`eleetnclight bu1b.[med:astintnn,Gk Skopein to View}
`,, me) Surgical:ncisienintethe
`
`do set regions [medtastmumGk
`
`
`
`mediasfln ‘
`asti’num) A median septum occupy-L:
`
`ing the int
`tween two parts of an organ, or
`two
`
`subdivisions of a region Speeiiicaliy, the spate betweenthetwo
`
`5‘ The superior
`” pleural sacs. This presentsfour Snbdiilis' i
`
`mediaslihttm [mediastinum superius '
`
`
`ieardinm and is bounded in frant by,
`
`__
`behind by the upper fonI tho ci‘c vertebrae and 1
`
`' trachea, oesophag ,
`mediastinal pleura It contai
`
`
`
`dnet the aerti'
`and Its bran es, the inneminate veimijnnd
`
`superior ve‘n
`hrenic nerve.; left reej‘irrem laryngeal nerve
`vagus nerve and cardiac branches,lymphatic glands, and the
`
`Medazepam {medatzemm) B? Commssmn appr ved name for
`' 7~chloro—23-Cliliydr’04amethyi-SnphenylaiH—14abenzodmz¢pmm
`a tranquillizer
`,
`,
`A
`1
`
`
`media {medeab).-«l. SeeMEDIU,
`
`(see below). Diophtric media, Refractmgmedia. In pinbal-
`mological emmmation, thetransparent optic fluids andtissues ‘L
`nil bronght
`
`
`to a focal ppin
`
`’eons bedy,andthe earned (L medias
`hamper, thelens, th
`
`
`