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J.P. Landers curriculum vitae
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`James Paul Landers
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`BIOGRAPHICAL
` Citizenship:
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`Dual - Canada/United States
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`EDUCATION
`1984 – 1988 Ph.D. Biochemistry [with distinction]; Department of Chemistry and Biochemistry, Univ. of Guelph, Canada
`1978 – 1983 B.Sc. Biochemistry (Biomedicine Minor); University of Guelph, Ontario, Canada
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`RESEARCH AND PROFESSIONAL
`Commonwealth Chaired Professor, University of Virginia
`Dec. 2015
`Director, Center for Nano-Biosystems Research, University of Virginia
`Dec. 2014
`Dec. 2001 Full Professor (untenured), Department of Chemistry, University of Virginia (Primary Appointment)
`Associate Professor, Department of Pathology, UVA Health Sciences Center (courtesy appointment)
`Professor, Department of Mechanical and Aerospace Engineering, UVA (courtesy appointment)
`1999–2001 Associate Professor (untenured), Department of Chemistry, University of Virginia, - Associate Professor,
`Department of Pathology, University of Virginia Health Sciences Center, Charlottesville, VA.
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`1997–1999 Assistant Professor, Department of Chemistry, University of Pittsburgh, Pittsburgh, PA.
`1996–1997 Associate Consultant, Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN.
`1994–1996 Director, Clinical Capillary Electrophoresis Facility, Division of Clinical Biochemistry and Immunology,
`Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN.
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`1990–1994 MRC Research Fellow, Mayo Clinic, Rochester, MN with T.C. Spelsberg.
`1988–1989 Research Fellow, Banting Institute, University of Toronto Medical School, Toronto, Canada with J.E. Kudlow
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`AWARDS • DISTINCTIONS • RECOGNITION
`2017 Named to the ‘Magnificent Tens’– Analytical Scientist Power List
`2017 Speaker at Nobel Symposium 162 in Stockholm
`2017 Appointed as Honorary Professor at Kaohsiung Medical University in Taiwan
`2016 Founded new Gordon Research Conference on Forensic Analysis of Human DNA
`2015 Founded UVA’s Center for Nano-Biosystems Research
`2015 Named Commonwealth Professor at UVA
`2014 Founded a new GRC on “Forensic Analysis of Human DNA”
`2014 Named a Jefferson Scholar Faculty Fellow at UVA
`2014 Bernard Langer Lecturer, Institute of Medical Science, University of Toronto
`2014 Appointed Visiting Professor and Lecturer, University of Toronto
`2014 Awarded the UVA Jefferson Scholars Foundation Award for Excellence in Teaching
`2103 Named Top-15 Forensic DNA Research Labs in the USA (by Forensics Colleges)
`2013 Chair, 29th International Conference on Microscale Bioseparations in the Life Sciences
`2013 Chair, Gordon Research Conference on Chemistry and Physics of Microfluidics
`2012 Bergveld Lecturer, University of Twente, Netherlands
`2011 Chair, 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences
`2011 Vice Chair, Gordon Research Conference on Chemistry and Physics of Microfluidics
`2011 Reached hirsch(10) Century status (>100 articles cited minimum of 10 times)
`2010 Awarded the Distinction of Fellow of the Royal Society of Chemistry
`2009 Vice Chair, Gordon Research Conference on Chemistry and Physics of Microfluidics
`2008 Awarded Association for Lab Automation ‘Innovative Technology of the Year’
`2007 Clifford C. Hatch Lecturer, University of Wyoming
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`2004 University of Virginia ‘Top-five’ List of Inventors
`2002 Awarded status of Fellow of the Royal Society of Chemistry
`1998 Lilly Analytical Chemistry Academic Contact Grant Award
`1991 Medical Research Council (MRC) of Canada Post-doctoral Fellowship
`1989 Mellon Foundation Post-doctoral Fellowship
`1989 Ph.D. awarded with distinction
`1989 Awarded the H.J. Suderman Award for Excellence in Graduate Teaching
`1984 University of Guelph ‘Dean of Graduate Studies’ Scholarship
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`PUBLISHED ARTICLES IN PEER-REVIEWED JOURNALS
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`General Statistics
`Total Papers (as of April-2018)
`Total Citations (as of April-2018)
`Average Citations per article
`Hirsch Index (h-index)
`Articles with >100 citations
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`255
`8,490
`35
` 50 (65 Google Scholar)
`19
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`1985 (1)
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` Bunce, N. J., Ingold., K. U., Landers, J.P., Lusztyk, J. and Scaiano, J. C. 1985. Kinetic study of photochlorination of 2,3-
`dimethylbutane and other alkanes in solution in the presence of benzene. JACS 107:5464-72. [*grandson of Sir Christopher
`Ingold – pioneer of reaction mechanisms and the electronic structure of organic compounds] DOI: 10.1021/ja00305a023 116
`citations
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`1987 (2)
`2 Bunce, N.J., Joy, R.B., Landers, J.P. and Nakai, J.S. 1987. Complexation effects in the photochlorination of 2,3-
`Dimethylbutane in the presence of fluorinated benzenes. J. Org. Chem. 52:1155-1156. DOI: 10.1021/jo00382a037 13
`citations
`3 Leece, B., Denomme, M. A., Towner, R. A., Li, S. M. A., Landers, J.P. and Safe, S. H. 1987. Non-additive interactive
`effects of polychlorinated biphenyl (PCB) congeners in the rat: role of the 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
`receptor protein. Can. J. Physiol. Biochem. 65:1978-1982.
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`1988 (3)
`4 Bunce, N.J., Landers, J.P., Langshaw, P. and Nakai. 1988. An assessment of the importance of direct solar degradation of
`some simple chlorinated benzenes and biphenyls in the vapor phase. Environ. Sci. Technol. 23:213-219. DOI:
`10.1021/es00179a013 PubMed ID: 2553709 23 citations
`5 Bunce, N. J., Landers, J.P. and Safe, S. H. 1988. Kinetic models for association of 2,3,7,8-Tetrachlorodibenzo-p-dioxin and
`the Ah receptor. Arch. Biochem. Biophys. 267:384-97. doi:10.1016/0003-9861(88)90044-6 39 citations
`6 Bunce, N. J., Landers, J.P. and Safe, S. H. 1988. Kinetics of the interaction between 2,3,7,8-tetrachlorodibenzo-p-dioxin
`and the Ah receptor protein. Chemosphere 18(1-6):731-736 DOI: 10.1016/0045-6535(89)90189-6
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`1989 (3)
`7 Bunce, N. J., Choong, D. K. M., Landers, J.P. and Zacharewski, T. R. 1989. Competitive binding of chlorinated azobenzenes
`to the Ah receptor protein. Environ. Chem. Toxicol. 8:25-30. DOI: 10.1897/1552-8618(1989)8[25:CBOCAT]2.0.CO;2 9
`citations
`8 Landers, J.P., Piskorksa-Pliszczynska, J., Zacharewski, T., Bunce, N. J. and Safe, S. H. 1989. Photoaffinity labelling of the
`nuclear Ah receptor from mouse Hepa 1c1c7 cells using [3H]-2,3,7,8-tetrachlorodibenzo-p-dioxin. J. Biol. Chem. 264:18463-
`18471. 26 citations
`9 Landers, J.P., Bunce, N. J., Nakai, J. S., Winhall, M. J. and Safe, S. H. 1989. Interspecies Differences In Invitro Thermal
`Inactivation Of Unliganded Hepatic Ah-Receptor Chemosphere 19:1241-1244. DOI: 10.1016/0045-6535(89)90440-2
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`1990 (5)
`10 Landers, J.P., Birse, L. M., Nakai, J. S., Winhall, M. J. and Bunce, N. J. 1990. Chemically-induced hepatic cytosol from the
`Sprague-Dawley Rat: Evidence for specific binding of 2,3,7,8-TCDD to components kinetically distinct from the Ah receptor.
`Toxicol. Lett. 51:295-302. DOI: 10.1016/0378-4274(90)90072-T 6 citations
`11 Landers, J.P. and Bunce, N. J. 1990. Hepatic Ah receptor from the Wistar rat: Role of solvation in receptor structure and
`inactivation. J. Biochem. Toxicol. 5:33-39. DOI: 10.1002/jbt.2570050106 8 citations
`12 Bunce. N.J., Landers, J.P., Nakai, J. S., Winhall, M. J. and Safe, S.H. 1990. Invitro Thermal Inactivation Of Hepatic Ah
`Receptors From Several Mammalian-Species Toxicol. In Vitro 4:87-92. DOI: 10.1016/0887-2333(90)90028-R 9 citations
`13 Bunce, N. J., Landers, J.P. and Safe, S. H., Schneider, U. A. and Zacharewski, T. 1990. Chlorinated Trans Stilbenes -
`Competitive-Binding To The Ah Receptor, Induction Of Cytochrome-P-450 Monooxygenase Activity And Partial 2,3,7,8-Tcdd
`Antagonism. Toxicol. Environ. Chem. 28:217-29. Doi: 10.1080/02772249009357605 7 Citations
`14 Landers, J.P., Safe, S. H., Bunce, N. J. 1990. [3H]-Tetrachlorodibenzo-p-dioxin: An efficient photoaffinity label for the Ah
`receptor. Chemosphere 20(7-9):1241-1248. DOI: 10.1016/0045-6535(90)90252-O
`15 Landers, J.P. and Bunce, N. J. 1990. The Ah receptor and the Mechanism of Toxicity. Biochemical J. 276:273-287. 286
`citations
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`1991 (7)
`16 Landers, J.P., Winhall, M. J., McCready, T., Sanders, D.A., Rasper, D., Nakai, J.S. and Bunce, N. J. 1991. Characterization
`of an inducible Aryl-Hydrocarbon receptor-like protein in rat liver. J. Biol. Chem. 266:9471-9480. PubMed ID: 1851747 20
`citations
`17 Landers, J.P. and Bunce, N. J. 1991. The Ah receptor and the mechanism of dioxin toxicity. [Review] Biochem. J. 276:273-
`287. PubMed ID: 1646595 296 citations
`18 Landers, J.P. and Spelsberg, T.C. 1991. The Unactivated Progesterone Receptor: the Presence and Role of Non-Receptor
`Protein Subunits (Commentary). Chemtracts: Biochemistry and Molecular Biology. March/April issue.
`19 Horton, M., Landers, J.P., Subramaniam, M., Goldberger, A., Toyoda, H., Littlefield, B., Hora, J., Gosse, B. and Spelsberg,
`T. C. 1991. Enrichment Of A 2nd Class Of Native Acceptor Sites For The Avian Oviduct Progesterone-Receptor As Intact
`Chromatin Fragments. Biochemistry 30:9523-9530. DOI: 10.1021/bi00103a020 5 citations
`20 Rejman, J., Landers, J., Goldberger, A., Schuchard, M., McCormick, D.J., Gosse, B. and Spelsberg, T.C. 1991. Purification
`of a nuclear protein (receptor binding factor-1) associated with the chromatin acceptor sites for the avian oviduct
`progesterone receptor. J. Prot. Chem. 10:651-667.
`21 Landers, J.P. and Spelsberg, T.C. 1991. Updates and new models for steroid hormone action. [Review] Ann. N.Y. Acad.
`Sci. 637:26-55. DOI: 10.1111/j.1749-6632.1991.tb27299.x 15 citations
`22 Landers, J.P. 1991. High performance capillary elec trophoresis of biological macromolecules. [Review] BioEssays
`13(5):252-258. DOI: 10.1002/bies.950130509 16 citations
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`1992 (5)
`23 Landers JP, Spelsberg TC. New concepts in steroid hormone action: transcription factors, proto-oncogenes, and the
`cascade model for steroid regulation of gene expression. Crit Rev Eukaryot Gene Expr. 1992;2(1):19-63. PubMed
`ID:1543897 176 citations
`24 Landers, J.P., Schuchard, M., Sismelich, T. and Spelsberg, T. C. 1992. High performance capillary electrophoretic analysis
`of chloramphenicol acetyl transferase (CAT) activity J. Chromatog. 603(1-2):247-257. DOI: 10.1016/0021-9673(92)85368-
`4 16 citations
`25 Landers, J.P., Oda, R.P., Madden, B., and Spelsberg, T. C. 1992. High-Performance Capillary Electrophoresis Of
`Glycoproteins - The Use Of Modifiers Of Electroosmotic Flow For Analysis Of Microheterogeneity. Anal. Biochem. 205:115-
`124. DOI: 10.1016/0003-2697(92)90587-W 115 citations
`26 Landers, J.P., Oda, R.P., Madden, B., Sismelich, T. and Spelsberg, T. C. 1992. Reproducibility Of Sample Separation
`Using Liquid Or Forced Air Convection Thermostated High-Performance Capillary Electrophoresis Systems. J. High Res.
`Chromatog. 15(8):517-525. IDS Number: JN012 15 citations
`27 Landers, J.P., Oda, R.P. and Schuchard, M.D. 1992. Separation of boron-complexed diol compounds using high
`performance capillary electrophoresis. Anal. Chem. 64(22):2846-2851. DOI: 10.1021/ac00046a032 59 citations
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`1993 (10)
`28 Oursler, M.-J., Landers, J.P. and Spelsberg, T.C. 1993. Estrogen effects on osteoblasts and osteoclasts. [Review] Ann.
`Med. 25:361-371. DOI: 10.3109/07853899309147298 68 citations
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`29 Landers, J.P., Oda, R.P., Leibenow, J., And Spelsberg, T. C. 1993. Utility Of High-Resolution Capillary Electrophoresis For
`Monitoring Peptide Homo-Dimer And Hetero-Dimer Formation. J. Chromatog. 652:109-117. DOI: 10.1016/0021-
`9673(93)80651-N 16 Citations
`30 Zhuang Y-H, Landers, J.P., Schuchard, M.D., Spelsberg T. C., and Tuohimaa P. 1993. Immunohistochemical localization
`of the avian progesterone receptor and its candidate receptor-binding factor, RBF-1. J. Cell. Biochem. 54:1-11. DOI:
`10.1002/jcb.240530416 6 citations
`31 Schuchard, M., Landers, J. P., Punkay, N. and Spelsberg, T. C. 1993. Steroid-Hormone regulation of the nuclear
`protooncogenes. Endocrin. Rev. 14(6): 659-669. DOI: 10.1210/er.14.6.659 143 citations
`32 Spelsberg, T.C., Subramaniam, M., Harris, S.A., Oursler, M.J., Schuchard, M.D., Landers, J.P. and Punkay, N. 1993.
`Nuclear proto-oncogenes as regulatory genes and markers of steroid action in all target cells. [Review] In "Proto-oncogenes
`and growth factors in steroid hormone-induced growth and differentiation." (G. Stancel, ed.) CRC Press, Boca Raton, FL.
`pp. 69-86.
`33 Spelsberg, T.C., Oursler, M.J., Landers, J.P., Subramaniam, M., Harris, S.A. and Riggs, B.L. 1993. Human Bone cells:
`Newly discovered target cells for sex steroids. [Review] In "Steroid Receptors", (V. Moudgil, ed.) Birkhauser Publishing,
`Boston, MA.
`34 Landers, J.P., Oda, R.P., Spelsberg, T.C., Nolan, J. and Ulfelder, K. 1993. Capillary electrophoresis: A powerful micro-
`analytical technique for biologically active molecules. Biotechniques 14(1):98-111. PubMed ID: 8424883 111 citations
`35 Landers J.P. 1993. Capillary Electrophoresis - Pioneering New Approaches For Biomolecular Analysis. [Review] TIBS
`18(11):409-414. DOI: 10.1016/0968-0004(93)90135-A 18 citations
`36 Tomlinson, A.J., Landers, J.P., Lewis, A.S.I. and Naylor, S. 1993. Buffer conditions affecting the separation of Maillard
`reaction products by capillary electrophoresis. J. Chromatog. 652:171-177. DOI: 10.1016/0021-9673(93)80657-T 32
`citations
`37 Tomlinson, A.J., Benson, L.M., Landers, J.P., Scanlon, G.F., Fang, J., Gorrod, J.W. and Naylor, S. 1993. Investigation of
`the metabolism of the neuroleptic drug haloperidol by capillary electrophoresis. J. Chromatog A. 652:417-426.
`doi:10.1016/0021-9673(93)83261-P 34 citations
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`1994 (5)
`38 Oda, R.P., Spelsberg, T.C. and Landers, J.P. 1994. Commercial capillary electrophoresis instrumentation. LC/GC
`12(1):50-51. Accession Number: WOS:A1994MP63800007 2 citations
`39 Landers, J. P., Subramaniam, M., Gosse, B., Weinshilboum, R. and Spelsberg, T. C. 1994. The ubiquitous nature of the
`receptor binding factor-1 (RBF-1) for the progesterone receptor in avian tissues. J. Cell. Biochem. 56:1-11. DOI:
`10.1002/jcb.240550211 6 citations
`40 Oda, R.P., Madden, B., Spelsberg, T. C. and Landers, J. P. 1994. Alpha,Omega-Bis-Quaternary Ammonium Alkanes As
`Effective Buffer Additives For Enhanced Capillary Electrophoretic Separation Of Glycoproteins J. Chromatogr. 680:85-92.
`DOI: 10.1016/0021-9673(94)80055-3 47 Citations
`41 Oda, R.P., Madden, B., Morris, J.C., Spelsberg, T. C. and Landers J.P. 1994. Multiple- buffer-additive strategies for
`enhanced capillary electrophoretic separation of peptides. J. Chromatogr. 680:341-351. DOI: 10.1016/0021-9673(94)80084-
`7 21 citations
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`1995 (8)
`42 Strausbauch, M.A., Xu, S.Z., Ferguson, J.E., Nunez, M., Machacek, D, Lawson, G.M., Wettstein,
`P.J. and Landers J.P. 1995. Concentration and analysis of hypoglycemic drugs using solid phase extraction-capillary
`electrophoresis. J. Chromatogr. 717:279-291. DOI: 10.1016/0021-9673(95)00743-6 62 citations
`43 Landers J.P. 1995. Clinical capillary electrophoresis. [Review] Clin. Chem. 41:495-509. PubMed ID: 7720237 87 citations
`44 Strausbauch, M.A., Madden, B.J., Wettstein, P.J. and Landers J.P. 1995. Sensitivity enhancement and
`second dimensional information from the SPE-CE analysis of entire HPLC fractions. Electrophoresis 16:541- 548.
`DOI: 10.1002/elps.1150160189 69 citations
`45 Felmlee, T.A.,Mitchell, P.S., Ulfelder, K.J., Persing, D.A. and Landers J.P. 1995. Capillary electrophoresis for the post-
`amplification detection of a hepatitis C virus-specific DNA product in human serum. J. Cap. Elect. 2:125- 130. 18
`citations
`46 Nunez, M.E., Ferguson, J.E., Machacek, D., G.M. Lawson, T.C. Spelsberg and Landers J.P. 1995. Detection of
`hypoglycemic drugs in human urine using micellar electrokinetic chromatography Anal. Chem. 67(20):3668-3675. DOI:
`10.1021/ac00116a009 38 citations
`47 Ji, A.J., Nunez, M.E., Machacek, D., Ferguson, J.E., Iossi, M.F., Kao, P.C. and Landers J.P. 1995. Separation of urinary
`estrogens by micellar electrokinetic chromatography. J. Chromatogr. 669:15-26. DOI: 10.1016/0378-4347(95)00143-7 55
`citations
`48 Felmlee, T.A., Oda, R.P., Persing, D.A. and Landers J.P. 1995. Capillary electrophoresis of DNA: application to clinical
`diagnoses. J.Chromatogr. 717:127-137. DOI: 10.1016/0021-9673(95)00491-2 33 citations
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`49 Oda, R.P. and Landers J.P. 1995. Application of capillary electrophoresis to the analysis of proteins. [Review]
`Bioseparations 5:315-328. 6 citations
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`1996 (5)
`50 Strausbauch, M., Landers J.P. and Wettstein, P.J. 1996. Mechanism of peptide separations by solid phase
`extraction-capillary electrophoresis (SPE-CE) at low pH. Anal. Chem. 68(2):306-314. DOI: 10.1021/ac9503217 97 citations
`51 Oda, R.P. and Landers J.P. 1996. High resolution glycoprotein analysis using capillary electrophoresis. [Review] Molec.
`Biotechnol. 5:165-170. DOI: 10.1007/BF02789064 7 citations
`52 Oda, R.P. and Landers, J.P. 1996. Effect of cationic buffer additives on the capillary electrophoretic separation of serum
`transferrin from different species. Electrophoresis 17(2):431-7.DOI: 10.1002/elps.1150170224 41 citations
`53 Clark, R., Namyst-Goldberg, C., Sanders, L., Oda, R.P., Katzmann, J.A., Kyle, R.A. and Landers, J.P. 1996. Rapid capillary
`electrophoretic analysis of human serum proteins: Qualitative comparison with high-throughput agarose gel electrophoresis.
`J. Chromatogr. 744(1):205-214. DOI: 10.1016/0021-9673(96)00190-2 35 citations
`54 Oda, R.P., Wick, M., Rueckert, L.M., Lust, J., and Landers, J.P. 1996. Evaluation of capillary electrophoresis in polymer
`solutions with laser-induced fluorescence detection for the automated detection of T-cell gene rearrangements in
`lymphoproliferative disorders. Electrophoresis 17(9):1491-1498. DOI: 10.1002/elps.1150170914 16 citations
`55 Oda, R.P. and Landers, J.P. 1996. High resolution glycoprotein analysis using capillary electrophoresis. Mol.
`Biotechnol. 5(2):165-170. DOI: 10.1007/BF02789064 7 citations
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`1997 (10)
`56 Roche, M., Oda, R.P., Machacek, D., Lawson, G.M. and Landers, J.P. 1997. Enhanced throughput with capillary
`electrophoresis via continuous-sequential sample injection. Anal. Chem. 69(1):99-104. DOI: 10.1021/ac960514+ 6 citations
`57 Pancholi, P., Oda, R.P., Mitchell, P.S., Persing, D.A. and Landers J.P. 1997. Diagnostic detection of herpes simplex and
`hepatitis C viral amplicons by capillary electrophoresis: Comparison with Southern blot detection. Molec. Diagnos.
`2(1):27-38. DOI: 10.1016/S1084-8592(97)80008-2 14 citations
`58 Katzmann, J.A., Clark, R., Namyst-Goldberg, C., Sanders, E., Kyle, R.A. and Landers, J.P. 1997. Identification of monoclonal
`proteins in serum: A quantitative comparison of acetate, agarose gel, and capillary electrophoresis. Electrophoresis 18:1775-
`80. DOI: 10.1002/elps.1150181011 29 citations
`59 Dong, M., Oda, Robert P., Strausbauch, M.A., Wettstein, P.J., Landers, J.P. and Miller, L.J. 1997. Hydrophobic peptide
`mapping of clinically relevant heptahelical membrane proteins by capillary electrophoresis. Electrophoresis 18:1767-74.
`DOI: 10.1002/elps.1150181010 23 citations
`60 Korf, G., O’Kane, D. and Landers J.P. 1997. Capillary electrophoresis with laser induced fluorescence detection for the
` Anal. Biochem. 251:210-218. DOI:
`analysis of
`free and
`immune complexed green
`fluorescent protein.
`10.1006/abio.1997.2242 23 citations
`61 Trushina, E., Oda, R.P., Clarke, N.J., Landers, J.P. and McMurray, C. 1997. Determination of nitrite and nitrate reduction
`by capillary ion electrophoresis. Electrophoresis 18:1890-1898. DOI: 10.1002/elps.1150181027 42 citations
`62 Oda, R.P., Clark, R.J., Katzmann, J.A., and Landers, J.P. 1997. Capillary electrophoresis as a clinical tool for the analysis
`of protein in serum and other body fluids. Electrophoresis 18:1715-23. DOI: 10.1002/elps.1150181004 42 citations
`63 Bergert, J., Liedtke, R., Oda, R.P., Landers, J.P., Wilson, D. 1997. Development of a nonisotopic capillary electrophoresis-
`based method for measuring glomerular filtration rate. Electrophoresis 18:1827-1835. DOI: 10.1002/elps.1150181018 15
`citations
`64 Roche, M., Oda, R.P., and Landers, J.P. 1997. Capillary electrophoresis for the detection of hypoglycemic drug metabolites
`in human urine. Electrophoresis 18:1865-1874. DOI: 10.1002/elps.1150181024 16 citations
`65 Oda, R.P., Prasad, R., Stout, R.L., Coffin, D., Patton, W.P., Kraft, D.L., O’Brien, J.F. and Landers, J.P. 1997. Capillary
`electrophoresis-based separation of transferrin sialoforms in patients with carbohydrate-deficient glycoprotein syndrome.
`Electrophoresis 18:1819-1826. PMID: 9372275 [PubMed - indexed for MEDLINE] DOI: 10.1002/elps.1150181017 46
`citations
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`1998 (9)
`66 Clark, R., Katzmann, J.A., Kyle, R., Fleisher, M. and Landers, J.P. 1998. Differential diagnosis of gammopathies by
`automated capillary electrophoresis: Analysis of serum samples problematic by agarose gel electrophoresis. Electrophoresis
`19(14):2479-84. PMID: 9820971 [PubMed - indexed for MEDLINE]
`67 Roche, M.E., Oda, R.P., and Landers, J.P. 1997. Capillary electrophoresis in Biotechnology. (review). Biotechnol. Prog.
`13(5): 659-668. DOI: 10.1021/bp970079k 13 citations
`68 Katzmann, J.A., Clark, R., Sanders, E. Landers, J.P. and Kyle, R.A. 1998. Prospective study of serum protein capillary
`zone electrophoresis and immunotyping of monoclonal proteins by immunosubtraction. Am. J. Clin. Pathol. 110:503-509.
`PubMed ID: 9763037 55 citations
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`69 Roche, M.E., Anderson, M.A., Oda, R.P., Riggs, L.B. Strausbauch, M.A., Okazaki, R. Wettstein, P.J. and Landers, J.P. 1998.
`Capillary electrophoresis of insulin-like growth factors: enhanced UV detection using dynamically-coated capillaries and on-
`line solid phase extraction (SPE-CE). Anal. Biochem. 258:87-95. DOI: 10.1006/abio.1997.2553 24 citations
`70 Borson, N.D., Strausbauch, M.A., Wettstein, P.J., Oda, R. P., Johnston, S.L., and Landers, J.P. 1998. Direct quantitation
`of RNA transcripts by competitive single-tube RT-PCR and capillary electrophoresis. BioTechniques 25(1):130 -137.
`PubMed ID: 9668987 40 citations
`71 Palmer, J., Atkinson, S., Yoshida, W.Y., Stalcup, A.M. and Landers, J.P. 1998. Charged chelate-capillary electrophoresis
`of endogenous corticosteroids Electrophoresis 19(16-17):3045-3051. DOI: 10.1002/elps.1150191642 11 citations
`72 Oda, R.P., Strausbauch, M.A., Borson, N., Hühmer, A.F.R., Jurrens, S., Craighead, J., Wettstein, P., Eckloff, B., Kline, B.
`and Landers, J.P. 1998. Infrared-mediated thermocycling for ultrafast polymerase chain reaction (PCR) amplification of
`DNA. Anal. Chem. 70(20):4361-4368. DOI: 10.1021/ac980452i PubMed ID: 9763037 140 citations
`73 Clark, R., Fleisher, M., Katzmann, J.A. and Landers, J.P. 1998. Differential diagnosis of gammopathies by automated
`capillary electrophoresis: Analysis of serum samples problematic by agarose gel electrophoresis. Electrophoresis
`19(14):2479-84. DOI: 10.1002/elps.1150191421 19 citations
`74 Tian, H., Hühmer A.F.R., Landers, J.P. 1998. New Vistas in Clinical Diagnostics: From Capillary Electrophoresis to Rapid
`Diagnostics on Glass Chips. Curr. Top. Anal. Chem. 1:171-189.
`
`1999 (9)
`75 Sanders, E., Katzmann, J.A., Clark, R., Oda, R.P., Shihabi, Z.K. and Landers, J.P. 1999. Development of capillary
`electrophoresis as an alternative to high resolution agarose electrophoresis for the diagnosis of multiple sclerosis. Clin.
`Chem. Lab. Med. 37(1):37-46. PMID: 10094377 [PubMed - indexed for MEDLINE] DOI: 10.1515/CCLM.1999.006 15
`citations
`76 Palmer, J.F., Munro, N., and Landers, J.P 1999. A universal concept for stacking neutral analytes in micellar electrokinetic
`chromatography. Anal. Chem. 71(9):1679-1687. DOI: 10.1021/ac981302a 188 citations
`77 Borson, N.D., Strausbauch, M.A., Kennedy, R.B., Oda, R. P., Landers, J.P. and Wettstein, P.J. 1999. Temporal sequence
`of transcription of perforin, fas ligand, tumor necrosis factor-a genes in rejecting skin allografts. Transplantation 67(5):672-
`680. PMID: 10096521 [PubMed - indexed for MEDLINE] 18 citations
`78 Dong, M., Ding XQ, Pinion, D I., Oda, R.P., Landers, J.P. and Miller, L.J. 1999. Structurally related peptide agonist, partial
`agonist and antagonist occupy a similar binding pocket within the cholecystokinin receptor. Rapid analysis using fluorescent
`photoaffinity labeling probes and capillary electrophoresis. J. Biol. Chem. 274(8):4778-4785. doi:10.1074/jbc.274.8.4778
`29 citations
`79 Munro, N., Palmer, J.F., Stalcup, A.M. and Landers, J.P. 1999. Charged Cyclodextrin-mediated sample stacking in micellar
`capillary electrophoresis: a simple method for enhancing the detection sensitivity of hydrophobic compounds. J. Chromatogr.
`731(2):369-381. doi:10.1016/S0378-4347(99)00258-3 PMID: 10510792 [PubMed - indexed for MEDLINE] 30 citations
`80 Munro, N.J., Snow, K., Kant, J. and Landers, J.P. 1999. Molecular diagnostics on microfabricated electrophoretic devices:
`from slab gel- to Capillary- to Microchip-based Assays for T- and B-cell lymphomoproliferative disorders. Clin. Chem.
`45:1906-17. 57 citations
`81 Hofgaertner, W., Hühmer, A.F.R., Landers J.P. and Kant, J. 1999. Rapid diagnosis of HSV-induced encephalitis:
`Electrophoresis of PCR products on microchips. Clin. Chem. 45:2120-8. 48 citations
`82 Huang, Z. Munro, N.M., Huhmer A, and Landers, J.P. 1999. Acousto-optic-based scanning of capillary and chip arrays for
`multichannel fluorescence detection of DNA. Anal . Chem. 71(23):5309-14. DOI: 10.1021/ac990740u 58 citations
`83 Trushina, G.V., Oda, R.P., and Landers J.P. 1999. Effective and reproducible capillary electrophoretic separation of thiols
`under conditions where exceptionally high current is generated. Anal. Chem. 71(24):5569-73. DOI: 10.1021/ac990505b
`PMID: 10624160 [PubMed - indexed for MEDLINE] 5 citations
`
`2000 (14)
`84 Trout A., Muza M.M. and Landers J.P. 2000. Capillary Electrophoresis of Proteins and Glycoproteins, in Encyclopedia of
`Analytical Chemistry, (R.A. Meyers - Ed), John Wiley & Sons, Chichester, 7:5649-5673.
`85 Oda, R.P., Strausbauch, M.A. and Landers, J.P. 1999. Peptide Analysis by Capillary Electrophoresis in Encyclopedia of
`Analytical Chemistry, (R.A. Meyers - Ed), John Wiley & Sons, Chichester, 7:5628–5648.
`86 Tian, H. Jaquins-Gerstl, A., Munro, N., Trucco, M., Brody L.C. and Landers J.P. 2000. Single-strand conformation
`polymorphism analysis by capillary and microchip electrophoresis: a fast, simple method for detection of common mutations
`in BCRA1 and BCRA2. Genomics 63(2): 31 -39. PMID: 10662541 [PubMed - indexed for MEDLINE]
`doi:10.1006/geno.1999.6067 94 citations
`87 Palmer, J. and Landers, J.P. 2000. Stacking neutral analytes in capillary electrokinetic chromatography with high-salt
`sample matrixes. Anal. Chem. 72(8):1941-1943. DOI: 10.1021/ac0000269 57 citations
`88 Giordano, B., Muza, M.M., Trout, A. and Landers, J.P. 2000. Dynamically-coated capillaries allow for capillary
`electrophoretic resolution of transferrin sialoforms via direct analysis of human serum. J Chromatogr B Biomed Sci Appl.
`742(1):79-89. doi:10.1016/S0378-4347(00)00128-6 39 citations
`
`
`
`8/12/18 10:45 PM
`
`Agilent Exhibit 1209
`Page 6 of 31
`
`

`

` J.P. Landers curriculum vitae
`
`
`
`Page 7
`
`89 Trout AL, Prasad R, Coffin D, DiMartini A, Lane T, Blessum C, Khatter N, Landers JP. 2000. Direct capillary electrophoretic
`detection of carbohydrate-deficient transferrin in neat serum. Electrophoresis. 21(12):2376-83. PMID: 10939448 [PubMed -
`indexed for MEDLINE] DOI: 10.1002/1522-2683(20000701)21:12<2376::AID-ELPS2376>3.0.CO;2-P 25 citations
`90 Tian, H., Hühmer, A.F.R., and Landers J.P. 2000. Evaluation of silica resins for the direct and efficient extraction of DNA
`from complex biological matrices in a miniaturized format. Anal. Biochem. 283(2):175-191. PMID: 10906238 [PubMed -
`indexed for MEDLINE] doi:10.1006/abio.2000.4577 170 citations
`91 Munro, N.J., Huang Z, Finegold, D.N. and Landers, J.P. 2000. Indirect fluorescence detection of amino acids on
`electrophoretic microchips. Anal. Chem. 72 (13):2765–2773. DOI: 10.1021/ac9914871 58 citations
`92 Tian, H., Brody, L.B. and Landers, J.P. 2000. Rapid detection of deletion, insertion, and substitution mutations via
`heteroduplex analysis using capillary- and microchip-based electrophoresis. Genom. Res. 10(9):1403-13. PMCID:
`PMC310899 doi:10.1101/gr.132700 73 citations
`93 Beisler AT, Kelly RH, Landers JP. 2000. Circumventing Complement C3 Interference in the Analysis of Carbohydrate-
`Deficient Transferrin in Fresh Serum. Anal. Biochem.. 285(1):143-150. DOI: 10.1006/abio.2000.4717 11 citations
`94 Landers, J.P. Molecular Diagnostics: It’s Closer Than You Might Think. Beckman Coulter Life - First Quarter 2000.
`95 Ferrance, J. and Landers, J.P. 2001. Exploiting sensitive laser-induced fluorescence detection on electrophoretic
`microchips for executing rapid clinical diagnostics. Luminescence 16(2):79-88. DOI: 10.1002/bio.646.abs 13 citations
`96 Hühmer, A.F.R. and Landers, J.P. 2000. Noncontact infrared-mediated thermocycling for effective polymerase chain
`reaction Amplification of DNA in nanoliter volumes. Anal. Chem. 72(21): 5507-5512. DOI: 10.1021/ac000423j 70
`citations
`98 Tian, H., Brody, L.B. Mao D. and Landers, J.P. 2000. Effective capillary electrophoresis-based heteroduplex analysis
`through surface coatings and polymers. Anal. Chem. 72(21): 5483-5492. doi:10.1021/ac0004916CCCPMID: 11080904
`[PubMed - indexed for MEDLINE] 32 citations
`
`
`
`
`2001 (12)
`99 Tian, H., Brody, L.B., Fan S., Huang Z, and Landers, J.P. 2001. Capillary and Microchip Electrophoresis for Rapid Detection
`of Known Mutations by Combining Allele-specific DNA Amplification with Heteroduplex Analysis. Clin. Chem. 47(2): 173-
`185. 44 citations
`100 Giordano, B., Copeland, E., and Landers, J.P. 2001. Towards dynamic coating of glass microchip chambers for amplifying
`DNA via the polymerase chain reaction. Electrophoresis 22(2): 334-340. PMID: 11288902 [PubMed - indexed for
`MEDLINE] DOI: 10.1002/1522-2683(200101)22:2<334::AID-ELPS334>3.0.CO;2-O 67 citations
`101 Palmer, J., Munro, N., Burgi, D. and Landers, J.P. 2001. Electrokinetic Injection for stacking of neutral
`analytes in capillary and microchip electrophoresis” Anal. Chem. 73(4):725-31. [for Editorial in Science on
`this work see Science 291(5504):555 (written by Phil Szuromi).] DOI: 10.1021/ac001046d 93 citations
`97 Dunsmoor, C., Sanders, J., Ferrance, J., Palmer, J. and Landers, J.P. 2001. Microchip Electrophoresis: An Emerging
`Technology for Biomedical and Clinical Applications LC-GC 14(10):38-44.
`98 Giordano, B., Ferrance, J., Hühmer, A.F.R., Swedberg, S. and Landers, J.P. 2001. Polymerase Chain Reaction in
`Polymeric Microchips: DNA Amplification
`in Less Than 240 Seconds. Anal. Biochem. 291(1): 124-132.
`doi:10.1006/abio.2000.4974 209 citations
`99 Munro, N., Hühmer, A.F.R. and Landers, J.P. 2001. Robust polymeric microchannel coatings for microchip-based analysis
`of neat PCR products. Anal. Chem. 73(8): 1784-94. DOI: 10.1021/ac001317k PMID: 11338592 [PubMed - indexed for
`MEDLINE] 45 citations
`100 Huang, Z., Sanders, J.C., Dunsmoor, C., and Landers, J.P. 2001. A Method for UV-bonding in the Fabrication of Glass
`Electrophoretic Microchips.
` Electrophoresis 22:3924-29. DOI: 10.1002/1522-2683(200110)22:18<3924::AID-
`ELPS3924>3.0.CO;2-4 PMID: 11700722 [PubMed - indexed for MEDLINE] 43 citations
`101 Jin, LJ, Giordano, BC and Landers, J.P. 2001. Dynamic Labeling During Capillary or Microchip Electrophoresis Allows for
`Laser-induced Fluorescence Detection of SDS-Protein Complexes Without Pre- or Post-column Labeling. Anal. Chem.
`73(20):4994-99. DOI: 10.1021/ac010590z 57 citations
`102 Strein, TG, Morris, D, Palmer, J. and Landers, J.P. 2001. A Discontinuous Electrophoretic Stacking System for Cholate-
`based EKC Separation of 8-Hydroxy-2'-Deoxyguanosine from Unmodified

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