!"ÿ$ÿ%$&&&&' !()*+,ÿ !"ÿ
`
` 



           


`   
`-./ÿ+*/./ÿ0123.ÿ+4ÿ5%61708ÿ5/91/:ÿ+*/ÿ74;<,/2+ÿ
`=>?@AÿB"ÿCBD=AD=Eÿÿ
`=>?@AÿB"ÿCBD=AD=Eÿ=Bÿ=FAÿBGAH>=IDJÿ>DKÿ"ID>DCI>@ÿHALIAMÿ>DKÿGHBEGAC=Eÿÿ
`IDKANÿ=Bÿ=FAÿCBDEB@IK>=AKÿ"ID>DCI>@ÿE=>=AOAD=Eÿÿ
`>LAD=IEÿJHB-GÿIDKANÿ=Bÿ=FAÿDB=AEÿ=Bÿ=FAÿCBDEB@IK>=AKÿ"ID>DCI>@ÿE=>=AOAD=Eÿÿ
`I+/,ÿ$P)ÿAQ*1R1+.ÿEAC-HI=IAEÿ>DKÿANCF>DJAÿCBOOIEEIBDÿ
`"BHOÿ !"
`M>EFIDJ=BDSÿK)C)ÿ TUP
`ÿV
`ÿ
`HAJIE=H>=IBDÿE=>=AOAD=ÿG-HE->D=ÿ=BÿEAC=IBDÿ$WRXÿBHÿWYXÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿ
`B"ÿ=FAÿEAC-HI=IAEÿANCF>DJAÿ>C=ÿB"ÿ$PZUÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿ
`ÿ
`BHÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿ
`[
`>DD->@ÿHAGBH=ÿG-HE->D=ÿ=BÿEAC=IBDÿ$ZÿBHÿ$TW7Xÿÿÿÿÿÿÿÿÿÿÿÿÿÿ
`^_`abcdÿ
`B"ÿ=FAÿEAC-HI=IAEÿANCF>DJAÿ>C=ÿB"ÿ$PZUÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿ
`"45ÿ+*/ÿ(1.;%0ÿ8/%5ÿ/27/7ÿK/;/,R/5ÿZ$Sÿ Zÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿ
`ÿ
`BHÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿ
`V =H>DEI=IBDÿHAGBH=ÿG-HE->D=ÿ=BÿEAC=IBDÿ$ZÿBHÿ$TW7Xÿÿÿÿÿÿÿÿÿÿÿÿÿÿ
`B"ÿ=FAÿEAC-HI=IAEÿANCF>DJAÿ>C=ÿB"ÿ$PZUÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿ
`"45ÿ+*/ÿ+5%2.1+142ÿ6/5147ÿ(54,ÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿ+4ÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿ
`C4,,1..142ÿ(10/ÿ2<,R/5\ÿ$!$&Z]&
`ÿ
`ÿ
`{|bÿ}~~c€}`ÿ
`–`~—c€ÿ|˜ÿ™š}a€`ÿ
`fghijkÿminoÿpqÿrostukvimkÿiuÿuwojtqtoxÿtmÿtkuÿjyivkovz
`‚ƒ„…†‡ˆ…‰Š‹†ÿ‹ÿŽŠ‡‰„…†‰‘‡ÿ†…’ÿŠ†‰‹ÿ“†ˆŠ‡”•ÿ
`‚›œ„Š‡Šž‰Š‹†ÿ‹ÿŠ†ž‹„Ÿ‹„…‰Š‹†ÿ‹„ÿ‹„…†Š …‰Š‹†•ÿ
`¡¢£¤¢ÿ¥bš}d|—š¦ÿ€`§`¨ÿ£ÿ
`ÿ
`™š}a€`ÿ
`ÿÿÿÿÿÿÿÿE/;<51+1/.ÿ5/Y1.+/5/7ÿ45ÿ+4ÿR/ÿ5/Y1.+/5/7ÿ6<5.<%2+ÿ+4ÿE/;+142ÿ$WRXÿ4(ÿ+*/ÿ>;+\
`f©xxvouuÿpqÿwvtmjtwiªÿohoj«kt¬oÿpqqtjouz
`­cb`ÿ|˜ÿ`}€®ÿ€}dd¯ÿ
`{}°`ÿ|˜ÿ`}€®ÿ`¨€®}a¦`ÿ|aÿ±®c€®ÿš`¦cdb`š`§
`>,/51;%2ÿK/64.1+%58ÿE*%5/.Sÿ/%;*ÿ5/65/./2+12Yÿ42/ÿB5712%58ÿE*%5/ÿ24,12%0ÿ9%0</ÿ²ÿZ)&
`ÿ
`D/:ÿ³453ÿE+4;3ÿAQ;*%2Y/
`6/5ÿ.*%5/
`ÿ
`B5712%58ÿE*%5/.Sÿ24,12%0ÿ9%0</ÿ²ÿZ)&ÿ6/5ÿ.*%5/´
`D/:ÿ³453ÿE+4;3ÿAQ;*%2Y/
`ÿ
`ÿ
`J<%5%2+//ÿ4(ÿ&$µ&¶ÿC<,<0%+19/ÿG5/(/5/2;/ÿE*%5/.ÿ4(ÿ>9/2+1.ÿB9/5./%.ÿ@+7
`D/:ÿ³453ÿE+4;3ÿAQ;*%2Y/
`ÿÿÿÿÿÿÿÿE/;<51+1/.ÿ5/Y1.+/5/7ÿ45ÿ+4ÿR/ÿ5/Y1.+/5/7ÿ6<5.<%2+ÿ+4ÿE/;+142ÿ$WYXÿ4(ÿ+*/ÿ>;+\
`ÿÿÿÿÿÿÿÿ>,/51;%2ÿK/64.1+%58ÿE*%5/.Sÿ/%;*ÿ5/65/./2+12Yÿ42/ÿ·<%5+/5ÿ4(ÿ%ÿG%5+1;16%+12YÿE*%5/ÿE/51/.ÿ>ÿ6%5ÿ9%0</ÿ²ÿ] )&Pÿ6/5ÿ.*%5/)´´
`ÿÿÿÿÿÿÿÿE/;<51+1/.ÿ(45ÿ:*1;*ÿ+*/5/ÿ1.ÿ%ÿ5/645+12Yÿ4R01Y%+142ÿ6<5.<%2+ÿ+4ÿE/;+142ÿ$TW7Xÿ4(ÿ+*/ÿ>;+\ÿD42/
`
` 



           


`  
`
`Mylan Ex.1069
`Mylan v. Sanofi - IPR2018-00176
`
`

`

`
` 



           


`   
`ÿ
`"#$%&'ÿ)*%ÿ+*,ÿ%,-'#).ÿ*,ÿ/0*%-%#*)ÿ10,1*$&$2ÿ30%ÿ*)45ÿ#)ÿ6*))&6%#*)ÿ7#%8ÿ%8&ÿ,&.#$%,-%#*)ÿ*+ÿ%8&ÿ9:&,#6-)ÿ;&1*$#%-,5ÿ<8-,&$ÿ10,$0-)%ÿ%*ÿ%8&ÿ,&/0#,&:&)%$ÿ*+ÿ%8&ÿ<&60,#%#&$
` !
`-)'ÿ=>68-).&ÿ?*::#$$#*)@ÿ
` !A8&ÿ9:&,#6-)ÿ;&1*$#%-,5ÿ<8-,&$ÿ,&1,&$&)%#).ÿB-,%#6#1-%#).ÿ<8-,&$ÿ<&,#&$ÿ9ÿ7&,&ÿ,&:*C&'ÿ+,*:ÿ4#$%#).ÿ-)'ÿ,&.#$%,-%#*)ÿ*)ÿ%8&ÿD&7ÿE*,Fÿ<%*6Fÿ=>68-).&ÿ&++&6%#C&
`ÿÿÿÿÿÿÿÿL)'#6-%&ÿ%8&ÿ)0:3&,ÿ*+ÿ*0%$%-)'#).ÿ$8-,&$ÿ*+ÿ&-68ÿ*+ÿ%8&ÿ#$$0&,M$ÿ64-$$&$ÿ*+ÿ6-1#%-4ÿ*,ÿ6*::*)ÿ$%*6Fÿ-$ÿ*+ÿ%8&ÿ64*$&ÿ*+ÿ%8&ÿ1&,#*'
`G045ÿHI2ÿIJJK@
`6*C&,&'ÿ35ÿ%8&ÿ-))0-4ÿ,&1*,%NÿÿÿÿÿÿÿÿOPQRSTPUÿWXTPYZ[ÿS\]RST^ÿ_T^`YÿaÿbcdeÿfYPÿWXTPYgÿdhe[eie[dhj
`ÿÿÿÿÿÿÿÿL)'#6-%&ÿ35ÿ68&6Fÿ:-,Fÿ78&%8&,ÿ%8&ÿ,&.#$%,-)%NÿI!ÿ8-$ÿ+#4&'ÿ-44ÿ,&1*,%$ÿ,&/0#,&'ÿ%*ÿ3&ÿ+#4&'ÿ35ÿ<&6%#*)ÿIHÿ*,ÿIK'!ÿ*+ÿ%8&ÿ<&60,#%#&$
`=>68-).&ÿ96%ÿ*+ÿIJHkÿ'0,#).ÿ%8&ÿ1,&6&'#).ÿIlÿ:*)%8$ÿ*,ÿ+*,ÿ$068ÿ$8*,%&,ÿ1&,#*'ÿ%8-%ÿ%8&ÿ,&.#$%,-)%ÿ7-$ÿ,&/0#,&'ÿ%*ÿ+#4&ÿ$068ÿ,&1*,%$!ÿ-)'
`l!ÿ8-$ÿ3&&)ÿ$03m&6%ÿ%*ÿ$068ÿ+#4#).ÿ,&/0#,&:&)%$ÿ+*,ÿ%8&ÿ1-$%ÿJnÿ'-5$@
`E&$ÿoÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿD*ÿp
`ÿÿÿÿÿÿÿÿL)'#6-%&ÿ35ÿ68&6Fÿ:-,Fÿ78#68ÿ+#)-)6#-4ÿ$%-%&:&)%ÿ#%&:ÿ%8&ÿ,&.#$%,-)%ÿ8-$ÿ&4&6%&'ÿ%*ÿ+*44*7@
`L%&:ÿIqÿpÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿÿL%&:ÿIrÿo
`ÿ
`stuWuvwxwyOvÿOzÿzyvxv{yx|ÿxv}ÿOw~utÿyvzOtxwyOvÿ
`ÿÿÿÿÿÿÿÿ<#)6&ÿG-)0-,5ÿI2ÿIJJJ2ÿ7&ÿ8-C&ÿ1034#$8&'ÿ*0,ÿ6*)$*4#'-%&'ÿ+#)-)6#-4ÿ$%-%&:&)%$ÿ#)ÿ&0,*$@ÿ€*,ÿ1&,#*'$ÿ1,#*,ÿ%*ÿG-)0-,5ÿI2ÿIJJJ2ÿ*0,
`6*)$*4#'-%&'ÿ+#)-)6#-4ÿ$%-%&:&)%$ÿ7&,&ÿ*,#.#)-445ÿ1,&1-,&'ÿ#)ÿ€,&)68ÿ+,-)6$ÿ-)'ÿ$03$&/0&)%45ÿ%,-)$4-%&'ÿ#)%*ÿ&0,*ÿ-:*0)%$ÿ-%ÿ%8&ÿ+#>&'
`4&.-4ÿ,-%&ÿ*+ÿÿI@nnÿ‚ÿ€€ÿƒ@KKJKq@ÿ„0,ÿ30$#)&$$ÿ6*:3#)-%#*)ÿ1-,%)&,ÿ…*&68$%ÿ8-$ÿ-4$*ÿ1034#$8&'ÿ#%$ÿ6*)$*4#'-%&'ÿ+#)-)6#-4ÿ$%-%&:&)%$ÿ#)
`&0,*$ÿ$#)6&ÿG-)0-,5ÿI2ÿIJJJ@ÿ€*,ÿ1&,#*'$ÿ1,#*,ÿ%*ÿG-)0-,5ÿI2ÿIJJJ2ÿ…*&68$%M$ÿ6*)$*4#'-%&'ÿ+#)-)6#-4ÿ$%-%&:&)%$ÿ7&,&ÿ*,#.#)-445ÿ1,&1-,&'ÿ#)
`†&,:-)ÿ:-,F$ÿ-)'ÿ$03$&/0&)%45ÿ%,-)$4-%&'ÿ#)%*ÿ&0,*ÿ-:*0)%$ÿ-%ÿ%8&ÿ+#>&'ÿ4&.-4ÿ,-%&ÿ*+ÿÿI@nnÿ‚ÿ;‡ÿI@JKKrH@ÿ<*4&45ÿ+*,ÿ%8&ÿ6*)C&)#&)6&ÿ*+
`%8&ÿ,&-'&,2ÿ%8#$ÿ9))0-4ÿˆ&1*,%ÿ6*)%-#)$ÿ%,-)$4-%#*)$ÿ*+ÿ6&,%-#)ÿ€,&)68ÿ+,-)62ÿ†&,:-)ÿ:-,Fÿ-)'ÿ&0,*ÿ-:*0)%$ÿ#)%*ÿ‰@<@ÿ'*44-,$ÿ-%ÿ$1&6#+#&'
`,-%&$@ÿŠ&ÿ'*ÿ)*%ÿ,&1,&$&)%ÿ%8-%ÿ%8&ÿ6*)C&,%&'ÿ-:*0)%$ÿ-6%0-445ÿ,&1,&$&)%ÿ$068ÿ‰@<@ÿ'*44-,ÿ-:*0)%$ÿ*,ÿ6*04'ÿ3&ÿ6*)C&,%&'ÿ#)%*ÿ‰@<@ÿ'*44-,$
`-%ÿ%8&ÿ,-%&$ÿ#)'#6-%&'ÿ*,ÿ-%ÿ-)5ÿ*%8&,ÿ,-%&@ÿE*0ÿ$8*04'ÿ-4$*ÿ)*%ÿ6*)$%,0&ÿ$068ÿ%,-)$4-%#*)$ÿ%*ÿ:&-)ÿ%8-%ÿ%,-)$4-%&'ÿ&0,*ÿ-:*0)%$ÿ,&4-%#).ÿ%*
`%8&ÿ,&$1&6%#C&ÿ+#)-)6#-4ÿ$%-%&:&)%$ÿ*+ÿ9C&)%#$ÿ-)'ÿ…*&68$%ÿ+*,ÿ1&,#*'$ÿ1,#*,ÿ%*ÿG-)0-,5ÿI2ÿIJJJÿ-,&ÿ'#,&6%45ÿ6*:1-,-34&@
`ÿÿÿÿÿÿÿÿ‰)4&$$ÿ*%8&,7#$&ÿ$%-%&'2ÿ%8&ÿ%,-)$4-%#*)$ÿ#)%*ÿ'*44-,$ÿ8-C&ÿ3&&)ÿ:-'&ÿ-%ÿ%8&ÿ,-%&ÿ*+ÿÿI@nnÿ‚ÿ‹ÿI@lKJq2ÿ%8&ÿD**)ÿŒ05#).ÿˆ-%&ÿ#)ÿD&7
`E*,Fÿ?#%5ÿ+*,ÿ6-34&ÿ%,-)$+&,$ÿ-$ÿ6&,%#+#&'ÿ+*,ÿ60$%*:$ÿ10,1*$&$ÿ35ÿ%8&ÿ€&'&,-4ÿˆ&$&,C&ÿŒ-)Fÿ*+ÿD&7ÿE*,Fÿ%8&ÿD**)ÿŒ05#).ÿˆ-%&!ÿ*)
`;&6&:3&,ÿHI2ÿlnnH@ÿ<&&ÿ=>68-).&ÿˆ-%&ÿL)+*,:-%#*)ÿ+*,ÿ#)+*,:-%#*)ÿ,&.-,'#).ÿ%8&ÿ€,&)68ÿ+,-)6Ž‰@<@ÿ'*44-,ÿ&>68-).&ÿ,-%&ÿ+,*:
`G-)0-,5ÿI2ÿIJJr2ÿ%*ÿ;&6&:3&,ÿHI2ÿIJJr2ÿ-)'ÿ%8&ÿ&0,*Ž‰@<@ÿ'*44-,ÿ&>68-).&ÿ,-%&ÿ$#)6&ÿG-)0-,5ÿI2ÿIJJJ@
`ÿÿÿÿÿÿÿÿ‰)4&$$ÿ*%8&,7#$&ÿ#)'#6-%&'2ÿ%8&ÿ+#)-)6#-4ÿ#)+*,:-%#*)ÿ,&4-%#).ÿ%*ÿ9C&)%#$ÿ6*)%-#)&'ÿ#)ÿ%8#$ÿ9))0-4ÿˆ&1*,%ÿ8-$ÿ3&&)ÿ1,&1-,&'ÿ#)
`-66*,'-)6&ÿ7#%8ÿ-66*0)%#).ÿ1,#)6#14&$ÿ.&)&,-445ÿ-66&1%&'ÿ#)ÿ€,-)6&ÿ6*::*)45ÿF)*7)ÿ-$ÿ€,&)68ÿ†99B!2ÿ78#68ÿ'#++&,$ÿ#)ÿ6&,%-#)
`$#.)#+#6-)%ÿ,&$1&6%$ÿ+,*:ÿ-66*0)%#).ÿ1,#)6#14&$ÿ.&)&,-445ÿ-66&1%&'ÿ#)ÿ%8&ÿ‰)#%&'ÿ<%-%&$ÿ6*::*)45ÿF)*7)ÿ-$ÿ‰@<@ÿ†99B!@ÿ<&&ÿD*%&ÿHkÿ%*
`%8&ÿ9C&)%#$ÿ?*)$*4#'-%&'ÿ€#)-)6#-4ÿ<%-%&:&)%$ÿ#)ÿ%8#$ÿ9))0-4ÿˆ&1*,%ÿ+*,ÿ%8&ÿ5&-,$ÿ&)'&'ÿ;&6&:3&,ÿHI2ÿlnnH2ÿlnnlÿ-)'ÿlnnIÿ#)640'&'ÿ-$
`1-,%ÿ*+ÿL%&:ÿIrÿ*+ÿ%8#$ÿ9))0-4ÿˆ&1*,%ÿ+*,ÿ-ÿ'&$6,#1%#*)ÿ*+ÿ%8&ÿ1,#)6#1-4ÿ'#++&,&)6&$ÿ3&%7&&)ÿ€,&)68ÿ†99Bÿ-)'ÿ‰@<@ÿ†99Bÿ-$ÿ%8&5ÿ,&4-%&ÿ%*
`9C&)%#$ÿ-)'ÿ#%$ÿ6*)$*4#'-%&'ÿ$03$#'#-,#&$ÿ-$ÿ7&44ÿ-$ÿ-ÿ,&6*)6#4#-%#*)ÿ%*ÿ‰@<@ÿ†99Bÿ*+ÿ)&%ÿ#)6*:&ÿ-)'ÿ$%*6F8*4'&,$Mÿ&/0#%5@
`ÿÿÿÿÿÿÿÿ‰)4&$$ÿ%8&ÿ6*)%&>%ÿ,&/0#,&$ÿ*%8&,7#$&ÿ#!ÿ9C&)%#$ÿ*,ÿŠ&ÿ,&+&,$2ÿ+*,ÿ1&,#*'ÿ1,#*,ÿ%*ÿ;&6&:3&,ÿIK2ÿIJJJ2ÿ%*ÿˆ8)&B*04&)6ÿ-)'ÿ%*
`9C&)%#$ÿ-)'ÿ#%$ÿ6*)$*4#'-%&'ÿ$03$#'#-,#&$ÿ+*,ÿ-44ÿ1&,#*'$ÿ3&.#))#).ÿ*,ÿ$03$&/0&)%ÿ%*ÿ;&6&:3&,ÿIK2ÿIJJJ2ÿ##!ÿ-44ÿ,&+&,&)6&$ÿ%*ÿ…*&68$%
`#)640'&ÿ…*&68$%ÿ9†ÿ-)'ÿ#%$ÿ6*)$*4#'-%&'ÿ$03$#'#-,#&$ÿ-$ÿ*+ÿ%8&ÿ,&4&C-)%ÿ'-%&2ÿ###!ÿ-44ÿ,&+&,&)6&$ÿ%*ÿ‰)#%&'ÿ<%-%&$ÿ*,ÿ‰@<@ÿ-,&ÿ%*ÿ%8&
`‰)#%&'ÿ<%-%&$ÿ*+ÿ9:&,#6-2ÿ,&+&,&)6&$ÿ%*ÿ'*44-,$ÿ*,ÿ‹ÿ-,&ÿ%*ÿ%8&ÿ60,,&)65ÿ*+ÿ%8&ÿ‰)#%&'ÿ<%-%&$@ÿˆ&+&,&)6&$ÿ%*ÿ€,-)6&ÿ-,&ÿ%*ÿ%8&ÿˆ&1034#6
`*+ÿ€,-)6&ÿ-)'ÿ,&+&,&)6&$ÿ%*ÿ€,&)68ÿ+,-)6$2ÿ+,-)6$ÿ*,ÿ€€ÿ-,&ÿ%*ÿ%8&ÿ60,,&)65ÿ*+ÿ€,-)6&ÿ1,#*,ÿ%*ÿG-)0-,5ÿI2ÿIJJJ@ÿˆ&+&,&)6&$ÿ%*ÿ&0,*$
`-)'ÿÿ-,&ÿ%*ÿ%8&ÿ60,,&)65ÿ*+ÿ%8&ÿIIÿ=0,*1&-)ÿ‰)#*)ÿ:&:3&,ÿ$%-%&$ÿ#)640'#).ÿ€,-)6&ÿ-)'ÿ†&,:-)5!ÿ1-,%#6#1-%#).ÿ#)ÿ=0,*1&-)ÿ‡*)&%-,5
`‰)#*)@ÿÿÿÿÿÿÿÿ<*6#-4ÿ-)'ÿ&)C#,*):&)%-4ÿ#)+*,:-%#*)ÿ#)640'&'ÿ#)ÿ%8&ÿ‡-)-.&:&)%ÿŒ*-,'ÿ,&1*,%ÿ%*ÿ3&ÿ1,&$&)%&'ÿ%*ÿ%8&ÿlnnkÿ9))0-4ÿ†&)&,-4ÿ‡&&%#).2
`#)ÿ-66*,'-)6&ÿ7#%8ÿ€,&)68ÿ?*::&,6#-4ÿ"-72ÿ-,&ÿ1,&$&)%&'ÿ#)ÿ%8&ÿ9C&)%#$ÿ<0$%-#)-3#4#%5ÿˆ&1*,%ÿ+*,ÿlnnH2ÿ78#68ÿ7&ÿ8-C&ÿ#)640'&'ÿ-$
`=>8#3#%ÿJJ@Iÿ%*ÿ%8&ÿ1,&$&)%ÿlnnHÿ9C&)%#$ÿ9))0-4ÿˆ&1*,%ÿ*)ÿ€*,:ÿln€@
`
` 



           


`  
`
`Mylan Ex.1069
`Mylan v. Sanofi - IPR2018-00176
`
`

`

`ÿ
`
` 



           


`   
`!"#$%&'"()ÿ+$"$,-,'$ÿ(,."(/%'.ÿ0&(1"(/23&&4%'.ÿ+$"$,-,'$+ÿ
`ÿÿÿÿÿÿÿÿ5676898:6;ÿ<:ÿ6=<;ÿ>::?7@ÿA8BCD6ÿD8E7DF<:Eÿ97:7E898:6G;ÿ8HB8I676<C:;Jÿ67DE86;ÿCDÿ<:68:6<C:;ÿCDÿ6Cÿ6=8ÿK?6?D8ÿB8DKCD97:I8ÿCD
`I<DI?9;67:I8;ÿCKÿ>L8:6<;Jÿ<:I@?F<:Eÿ79C:EÿC6=8Dÿ6=<:E;Jÿ;676898:6;ÿIC:67<:<:EÿBDCM8I6<C:;ÿCDÿ8;6<9768;ÿCKÿD8L8:?8;Jÿ<:IC98Jÿ87D:<:E;ÿB8D
`;=7D8JÿI7B<67@ÿ8HB8:F<6?D8;JÿI7B<67@ÿ;6D?I6?D8JÿCDÿC6=8DÿK<:7:I<7@ÿ<689;NÿB@7:;ÿ7:FÿCOM8I6<L8;ÿD8@76<:Eÿ6CÿK?6?D8ÿCB8D76<C:;JÿBDCF?I6;JÿCD
`;8DL<I8;NÿK?6?D8ÿ8IC:C9<IÿB8DKCD97:I8NÿCDÿ7;;?9B6<C:;ÿ?:F8D@P<:EÿCDÿD8@76<:Eÿ6Cÿ7:Pÿ;?I=ÿ;676898:6;Jÿ7D8ÿKCDQ7DFR@CCS<:Eÿ;676898:6;ÿ6=76
`7D8ÿO7;8FÿC:ÿ6=8ÿI?DD8:6ÿ8HB8I676<C:;ÿ7:Fÿ8;6<9768;ÿCKÿ>L8:6<;ÿ97:7E898:6Jÿ7:Fÿ7D8ÿ;?OM8I6ÿ6CÿD<;S;ÿ7:Fÿ?:I8D67<:6<8;Tÿ>I6?7@ÿD8;?@6;ÿ97P
`F<KK8Dÿ9768D<7@@PÿF8B8:F<:EÿC:ÿK7I6CD;ÿ6=76ÿ97Pÿ<:I@?F8JÿO?6ÿ7D8ÿ:C6ÿ@<9<68Fÿ6CJÿ7:PÿCKÿ6=8ÿKC@@CQ<:EU
`V
`K7<@?D8ÿ6Cÿ7I=<8L8ÿ;7@8;ÿEC7@;ÿF?8ÿ6CÿIC9B86<6<C:ÿCDÿ97DS86ÿ7II8B67:I8ÿCKÿC?DÿBDCF?I6;Nÿÿ
`ÿ
`V
`;?II8;;K?@ÿ<:6DCF?I6<C:ÿCKÿE8:8D<IÿIC9B86<6CD;ÿ6Cÿ7:PÿCKÿC?Dÿ;6D768E<IÿOD7:F;Nÿÿ
`ÿ
`V
`?:8HB8I68Fÿ:8E76<L8ÿD8;?@6;ÿKDC9ÿD8;87DI=ÿ7:FÿF8L8@CB98:6ÿCDÿI@<:<I7@ÿ6D<7@;ÿCKÿI?DD8:6ÿBDCF?I6ÿI7:F<F768;Nÿÿ
`ÿ
`V
`K7<@?D8ÿ6CÿCO67<:JÿCDÿ?:8HB8I68FÿF8@7P;ÿ<:ÿCO67<:<:EJÿ:8QÿBDCF?I6ÿ7:Fÿ6=8D7B8?6<Iÿ<:F<I76<C:ÿD8E?@76CDPÿ7BBDCL7@;N
`<
`V
`?:K7LCD7O@8ÿ8HI=7:E8ÿD768ÿ9CL898:6;JÿB7D6<I?@7D@PÿO86Q88:ÿ6=8ÿWT5TÿFC@@7Dÿ7:Fÿ6=8ÿ8?DCNÿÿ
`ÿ
`V
`F8@7Pÿ<:JÿCDÿK7<@?D8ÿ6Cÿ7I=<8L8ÿ8HB8I68Fÿ@8L8@;ÿCKÿ:86ÿBDCI88F;ÿKDC9Jÿ;7@8;ÿCKÿ7;;86;Nÿÿ
`ÿ
`V
`<:6DCF?I6<C:ÿCKÿ:8QÿCDÿD8L<;8FÿD8E?@76<C:;ÿCDÿD8X?<D898:6;ÿB8D67<:<:Eÿ6CÿBDCF?I6ÿ7BBDCL7@JÿBDCF?I6ÿ;7K86PJ
`8:L<DC:98:67@ÿBDC68I6<C:ÿCDÿ97:?K7I6?D<:EÿBDCI8;;8;Nÿÿ
`ÿ
`V
`D8E?@76CDPÿ7I6<C:;ÿ6=76ÿ7D8ÿ8<6=8Dÿ?:8HB8I68FÿCDÿ<:CBBCD6?:8@Pÿ6<98FNÿÿ
`ÿ
`V
`76689B6;ÿOPÿ6=<DFÿB7D6<8;ÿ6CÿCO67<:ÿCQ:8D;=<BÿCDÿIC:6DC@ÿCKÿ>L8:6<;ÿQ<6=C?6ÿ6=8ÿ;?BBCD6ÿCKÿ>L8:6<;ÿ97:7E898:6Nÿÿ
`ÿ
`V
`B768:6ÿBDC68I6<C:ÿ6=76ÿBDCL8;ÿ<:8KK8I6<L8Nÿÿ
`ÿ
`V
`?:8HB8I68Fÿ@<6<E76<C:ÿIC;6;ÿCDÿ@<7O<@<6<8;Nÿ7:Fÿÿ
`ÿ
`V
`C6=8DÿD<;S;ÿ7:Fÿ?:I8D67<:6<8;ÿ6=76ÿ7D8ÿF<KK<I?@6ÿ6CÿBD8F<I6T
`ÿÿÿÿÿÿÿÿ588ÿYZ689ÿ[Tÿ\8PÿZ:KCD976<C:ÿ]ÿA<;Sÿ^7I6CD;YÿKCDÿK?D6=8Dÿ<:KCD976<C:ÿD8E7DF<:EÿD<;S;ÿ7:Fÿ?:I8D67<:6<8;ÿ6=76ÿIC?@FÿI7?;8ÿ7I6?7@ÿD8;?@6;
`6CÿF<KK8Dÿ9768D<7@@PÿKDC9ÿ6=8;8ÿKCDQ7DFR@CCS<:Eÿ;676898:6;T
`ÿ
`#+,ÿ&0ÿ_("'/ÿ'"-,+ÿ%'ÿ$`%+ÿ(,a&($ÿ
`ÿÿÿÿÿÿÿÿbD7:Fÿ:798;ÿ7BB87D<:Eÿ<:ÿ<67@<I;ÿ6=DC?E=C?6ÿ6=<;ÿ>::?7@ÿA8BCD6ÿ7D8ÿ6D7F897DS;ÿCKÿ>L8:6<;ÿ7:FcCDÿ<6;ÿ7KK<@<768;JÿQ<6=ÿ6=8ÿ8HI8B6<C:ÿCKU
`]
`6D7F897DS;ÿ?;8FÿCDÿ6=76ÿ97PÿO8ÿ?;8Fÿ?:F8Dÿ@<I8:;8ÿOPÿ>L8:6<;ÿ7:FÿcCDÿ<6;ÿ7KK<@<768;Jÿ;?I=ÿ7;ÿdefghijJÿ7ÿ6D7F897DSÿCK
`6=8ÿkDC?BÿlDCI68Dÿmÿk79O@8ÿl=7D97I8?6<I7@;JÿdjnioegJÿ7ÿ6D7F897DSÿCKÿ6=8ÿkDC?Bÿ>@67:7ÿl=7D97ÿ>kJÿpqrsfgtÿ7
`6D7F897DSÿCKÿ6=8ÿkDC?Bÿ\7O?;=<S<ÿ\7<;=7ÿu7S?@6ÿvC:;=7Jÿpgsqwghitÿ7ÿ6D7F897DSÿCKÿ6=8ÿkDC?Bÿx8L7
`l=7D97I8?6<I7@ÿZ:F?;6D<8;Jÿyzq{is|}}Jÿ7ÿ6D7F897DSÿCKÿl8B6CDÿ~6FJÿw€i‚qtÿ7ÿ6D7F897DSÿCKÿ6=8ÿkDC?BÿlK<ƒ8D
`lDCF?I6;ÿZ:ITJÿ„ihqoihoiJÿ7ÿ6D7F897DSÿCKÿk8:67ÿZ:Iÿ<:ÿ6=8ÿW5>Jÿ…qnqhzeJÿ7ÿ6D7F897DSÿCKÿ6=8ÿkDC?Bÿ†7<<I=<
`l=7D97I8?6<I7@ÿ‡CTÿ~6FTJÿˆ€fq‰‚zsJÿ7ÿ6D7F897DSÿCKÿZ:;6<6?6ÿl7;68?DJÿŠqofihtÿ7ÿ6D7F897DSÿCKÿ6=8ÿkDC?Bÿ‹TATÿ5X?<OOÿm
`5C:;JÿZ:ITÿÿ
`ÿ
`]
`6D7F897DS;ÿ;C@FÿOPÿ>L8:6<;ÿ7:FcCDÿ<6;ÿ7KK<@<768;Jÿ;?I=ÿ7;ÿdhozgjzhJÿ7ÿ6D7F897DSÿCKÿ6=8ÿkDC?Bÿ>@9<D7@@ÿlDCF8;K7D97
`5TBT>TJÿpq‚Œzirtÿ7ÿ6D7F897DSÿCKÿ6=8ÿkDC?Bÿb<CL7<@ÿC:@Pÿ<:ÿ6=8ÿW5>Jÿpq‚qŽqfitÿ€je‚qfitÿ‘ihf’jtÿ‘ihf’jgjÿ7:F
`{‚gefgoiŒ’jÿ“C:@Pÿ<:ÿ6=8ÿWT5Tÿ7:Fÿ‡7:7F7”Jÿ7:Fÿyij€‚oqhJÿ6D7F897DS;ÿCKÿ6=8ÿkDC?Bÿ>HI7:ÿl=7D97ÿZ:ITJÿpgje•zrqwJ
`7ÿ6D7F897DSÿCKÿ~7OCD76C<D8ÿF8ÿ@G–BCI7@I<?9ÿ<:ÿ^D7:I8Jÿ—ghqrzhJÿ7ÿ6D7F897DSÿCKÿ6=8ÿkDC?Bÿ˜8F8L7ÿl=7D97I8?6<I7@
`˜7:?K7I6?D8D;ÿZ:ITÿ8HI8B6ÿ<:ÿ‡7:7F7ÿ7:Fÿ5B7<:Jÿfq‚™zhšJÿ7ÿ6D7F897DSÿCKÿ6=8ÿkDC?Bÿb7P8Dÿ>kJÿ€nih’@Jÿ7
`
` 



           


`
`  
`
`Mylan Ex.1069
`Mylan v. Sanofi - IPR2018-00176
`
`

`

` !"#$! %ÿ'(ÿ)#ÿ* '+,ÿ-)+.!/ÿ0)! $!1#+/1!2ÿ-'34"5ÿ6789:;<=5ÿ!ÿ !"#$! %ÿ'(ÿ>/?.ÿ0)! $!1#+/1!2@3ÿÿ
`   
`
` 



           


`ÿ
`A
`B:<CD:E5ÿ!ÿ !"#$! %ÿ'(ÿ)#ÿ* '+,ÿF!?'(/GFH?)I2!J'5ÿK<L:Mÿ/?ÿ)#ÿN3F3OÿEÿ !"#$! %ÿ'(ÿQ!H# ÿR*5ÿKSE:<D<85ÿ!
` !"#$! %ÿ'(ÿ)#ÿ* '+,ÿF1)# /?.ÿ-' ,' !/'?5ÿTUMV9;OÿWL:<89COÿX:M8DS<895ÿ !"#$! %@ÿ'(ÿY# /!2ÿ!?"ÿZ9CEUE;Oÿ!
` !"#$! %ÿ'(ÿR[#?/@ÿ0!@#+ ÿYF\3
`//ÿ
`]^_`aÿcdÿecf]af]gÿ
`hijklmnoÿ
`ÿÿÿ
`p#$ÿÿÿq
`ÿ>#Hÿp?(' $!/'?
`ÿ
`ÿÿÿÿÿÿÿÿÿF#2#1#"ÿr/?!?1/!2ÿ\!!
`ÿ
`ÿÿÿÿÿÿÿÿÿst1)!?.#ÿu!#ÿp?(' $!/'?
`ÿ
`ÿÿÿÿÿÿÿÿÿu/@%ÿr!1' @
`p#$ÿÿÿv
`ÿp?(' $!/'?ÿ'?ÿ)#ÿ-'$,!?H
`ÿ
`ÿÿÿÿÿÿÿÿÿ0 '(/2#ÿ!?"ÿF !#.H
`ÿ
`ÿÿÿÿÿÿÿÿÿ0 '"+1@
`ÿ
`ÿÿÿÿÿÿÿÿÿu#@#! 1)ÿ!?"ÿ\#[#2',$#?
`ÿ
`ÿÿÿÿÿÿÿÿÿ0 ',# H5ÿ02!?ÿ!?"ÿsw+/,$#?
`ÿ
`ÿÿÿÿÿÿÿÿÿY! %#@
`ÿ
`ÿÿÿÿÿÿÿÿÿx'?G-' #ÿQ+@/?#@@
`p#$ÿÿÿy
`ÿz,# !/?.ÿ!?"ÿr/?!?1/!2ÿu#[/#{ÿ!?"ÿ0 '@,#1@
`ÿ
`ÿÿÿÿÿÿÿÿÿu#@+2@ÿ'(ÿz,# !/'?@|ÿ}~~qÿ1'$,! #"ÿ'ÿ}~~}
`ÿ
`ÿÿÿÿÿÿÿÿÿu#@+2@ÿ'(ÿz,# !/'?@|ÿ}~~}ÿ1'$,! #"ÿ'ÿ}~~
`p#$ÿÿÿ€
`ÿ\/ #1' @5ÿF#?/' ÿY!?!.#$#?ÿ!?"ÿs$,2'H##@
`p#$ÿÿÿ
`ÿY!‚' ÿF)! #)'2"# @ÿ!?"ÿu#2!#"G0! Hÿƒ !?@!1/'?@
`p#$ÿÿÿ„
`ÿr/?!?1/!2ÿp?(' $!/'?
`p#$ÿÿÿ…
`ÿƒ)#ÿz((# ÿ!?"ÿ4/@/?.
`ÿ
`ÿÿÿÿÿÿÿÿÿY! %#@
`ÿ
`ÿÿÿÿÿÿÿÿÿƒ !"/?.ÿ0 !1/1#@ÿ!?"ÿ0 '1#"+ #@
`p#$ÿ~
`ÿR""//'?!2ÿp?(' $!/'?
`ÿ
`ÿÿÿÿÿÿÿÿÿF)! #ÿ-!,/!2ÿ!?"ÿQHG4!{@
`ÿ
`ÿÿÿÿÿÿÿÿÿƒ!t!/'?
`p#$ÿ
`ÿ†+!?/!/[#ÿ!?"ÿ†+!2/!/[#ÿ\/@12'@+ #ÿ!J'+ÿY! %#ÿu/@%
`p#$ÿy
`ÿ-'? '2@ÿ!?"ÿ0 '1#"+ #@
`p#$ÿ€R
`ÿR+"/ÿ-'$$/##ÿr/?!?1/!2ÿst,# 
`p#$ÿ€Q
`ÿ-'"#ÿ'(ÿs)/1@
`p#$ÿ€-
`ÿR11'+?!?@‡ÿr##@ÿ!?"ÿF# [/1#@
`p#$ÿ„
`ÿ-'?@'2/"!#"ÿr/?!?1/!2ÿF!#$#?@
`p#$ÿ…
`ÿst)/J/@
`////[ÿ‹^Œ]ÿhÿ
`p#$@ÿ5ÿ}5ÿ}ÿ!?"ÿÿ! #ÿ?'ÿ #w+/ #"ÿ(' ÿ)/@ÿ!??+!2ÿ #,' ÿ'?ÿr' $ÿ}~Gr3ÿp#$@ÿqÿ!?"ÿvÿ! #ÿ?'ÿ!,,2/1!J2#ÿ'ÿR[#?/@ÿ(' ÿ)#ÿ,# /'"ÿ1'[# #"ÿJHÿ)/@ÿ #,' 3
`ˆ‰Š
`hijkÿŽÿÿÿÿhji‘i’ÿ“”ÿ•‘–j—i“–l˜ÿgj‘“–ÿ™šš›jkjiÿšÿ^œ‘lj–lÿ
`ÿÿÿÿÿÿÿÿx'ÿR,,2/1!J2#3
`
` 



           


`
`  
`
`Mylan Ex.1069
`Mylan v. Sanofi - IPR2018-00176
`
`

`

`ÿ !"#ÿ%&ÿÿÿÿ'((")ÿ*!+!,-!,.-ÿ+/0ÿ123".!"0ÿ4,#"!+56"ÿ
`
` 



           


`   
`ÿÿÿÿÿÿÿÿ789ÿ:;;<=>?@<AB
`CD
`ÿ !"#ÿE&ÿÿÿÿF"Gÿ /(H)#+!,H/ÿ
`*"6".!"0ÿI,/+/.,+6ÿJ+!+ÿ
`ÿÿÿÿÿÿÿÿKLAÿ9?@<AMÿ@A<8NÿMA9ÿO8P9LÿMA<A>9AQÿ>8RM8<=Q?9AQÿO=R?R>=?<ÿQ?9?ÿO8Pÿ:SAR9=MÿO8PÿA?>Lÿ8Oÿ9LAÿO=SAÿTA?PMÿQUP=RVÿ9LAÿ;AP=8QÿARQAQ
`WA>AX@APÿYCZÿD[[YZÿ;PA;?PAQÿ=Rÿ?>>8PQ?R>AÿN=9LÿVARAP?<<Tÿ?>>A;9AQÿ?>>8UR9=RVÿ;P=R>=;<AMÿ=Rÿ\P?R>ABÿKLAMAÿO=R?R>=?<ÿQ?9?ÿ?PAÿQAP=SAQÿOP8X
`9LAÿ:SAR9=Mÿ]8RM8<=Q?9AQÿ\=R?R>=?<ÿ^9?9AXAR9MZÿNL=>LÿL?SAÿ@AARÿ?UQ=9AQÿ@Tÿ_P=>AN?9APL8UMA]88;APMZÿ=RQA;ARQAR9ÿ?UQ=98PMBÿKLAÿMA<A>9AQ
`>8RM8<=Q?9AQÿO=R?R>=?<ÿQ?9?ÿO8PÿD[[CZÿD[[Dÿ?RQÿD[[YÿML8U<Qÿ@AÿPA?Qÿ=Rÿ>8R`UR>9=8RÿN=9Lÿ9LAÿ:SAR9=Mÿ]8RM8<=Q?9AQÿ\=R?R>=?<ÿ^9?9AXAR9Mÿ?RQ
`9LAÿPA<?9AQÿR89AMÿ=R><UQAQÿA<MANLAPAÿ=Rÿ9L=Mÿ:RRU?<ÿaA;8P9Bÿ^AAÿbc9AXÿCdBÿ]8RM8<=Q?9AQÿ\=R?R>=?<ÿ^9?9AXAR9MbÿO8PÿOUP9LAPÿ=RO8PX?9=8RB
`ÿÿÿÿÿÿÿÿKLAÿVARAP?<<Tÿ?>>A;9AQÿ?>>8UR9=RVÿ;P=R>=;<AMÿ=Rÿ\P?R>AÿefR8NRÿ?Mÿ\PAR>Lÿg::_hÿ?Mÿ?;;<=AQÿ@Tÿ:SAR9=MÿQ=OOAPÿ=RÿM=VR=O=>?R9ÿPAM;A>9M
`OP8XÿVARAP?<<Tÿ?>>A;9AQÿ?>>8UR9=RVÿ;P=R>=;<AMÿ=Rÿ9LAÿiR=9AQÿ^9?9AMÿeiB^Bÿg::_hBÿ\8Pÿ?ÿQ=M>UMM=8Rÿ8Oÿ9LAÿ;P=R>=;?<ÿQ=OOAPAR>AMÿ?Mÿ9LAT
`PA<?9Aÿ98ÿ:SAR9=MZÿ?RQÿ?ÿPA>8R>=<=?9=8Rÿ8OÿRA9ÿ=R>8XAÿ?RQÿ989?<ÿM98>fL8<QAPMjÿAkU=9TÿO8Pÿ9LAÿ9LPAAÿTA?PMÿARQAQÿWA>AX@APÿYCZÿD[[YZÿD[[Dÿ?RQ
`D[[Cÿ98ÿiB^Bÿg::_ZÿMAAÿ789AÿYlÿ98ÿ9LAÿ:SAR9=Mÿ]8RM8<=Q?9AQÿ\=R?R>=?<ÿ^9?9AXAR9Mÿ=R><UQAQÿ=Rÿ9L=Mÿ:RRU?<ÿaA;8P9ÿ?9ÿc9AXÿCdB
`ÿ
`mn"/!,-ÿ*"6".!"0ÿoH/-H6,0+!"0ÿI,/+/.,+6ÿJ+!+ÿ
`IH)ÿ!p"ÿG"+)ÿ"/0"0ÿ+/0ÿ+-ÿH(ÿJ"."#5")ÿEqr
`ÿÿ
`ÿ
`ÿ
`ÿ%ssEtquÿ%ssEÿ%ss%ÿ%ssqÿ%sssÿqvvvt%uÿ
`ÿÿ
`ÿ wÿÿÿ xÿÿÿ xÿÿÿ xÿÿÿ xÿÿÿ xÿÿÿ
`ÿÿ
`t,/ÿ#,66,H/-rÿ"2."3!ÿ(H)ÿ!p"ÿ/y#5")ÿH(ÿH)0,/+)Gÿ-p+)"-rÿ
`ÿ
`zp,.pÿ,-ÿ,/ÿ!pHy-+/0-rÿ+/0ÿ!p"ÿ3")ÿ-p+)"ÿ0+!+uÿ
`ÿÿ
`ÿ
`ÿ
` /.H#"ÿ-!+!"#"/!ÿ0+!+{
`ÿ
`ÿÿ
`ÿÿ
`ÿÿ
`ÿÿ
`ÿÿ
`ÿÿ
`7A9ÿM?<AM
`CDZ}dÿ
`ÿ
`DDZllDÿ
`C|ZdC}ÿ
`D[Z~DDÿ
`DDZlCÿ
`DDZY[lÿ
`€;AP?9=RVÿ=R>8XAÿe<8MMh
`e}llh
`ÿ
`lZ~DYÿ
`YZ~|[ÿ
`DZdY[ÿ
`YZ~Yÿ
`~C|ÿ
`cR>8XAÿe<8MMhÿ@AO8PAÿ9?AMÿ?RQÿX=R8P=9T
`edDYh
`=R9APAM9M
`ÿ
`YZ~~|ÿ
`DZCCÿ
`YZ~Dÿ
`DZdd~ÿ
`eD}h
`_P8S=M=8RÿO8Pÿ=R>8XAÿ9?AM
`lDÿ
`ÿ
`eCZC|[h
`eDh
`eCZlY[h
`eCZCCCh
`e~[h
`‚=R8P=9Tÿ=R9APAM9M
`e|[h
`ÿ
`eY|h
`eDh
`ed~h
`eClDh
`ed}h
`7A9ÿ=R>8XAÿe<8MMhÿ@AO8PAÿ;PAOAPPAQ
`ed}Ch
`PAXURAP?9=8R
`ÿ
`eDZl~[h
`CZ}Yÿ
`DZC|~ÿ
`CZ~YYÿ
`eDh
`_PAOAPPAQÿPAXURAP?9=8ReYh
`eCCh
`ÿ
`e~~h
`e}Dh
`ed}h
`eCDdh
`eCCdh
`7A9ÿ=R>8XAÿ?S?=<?@<AÿO8PÿQ=M9P=@U9=8Rÿ98
`e|[h
`>8XX8RÿML?PAL8<QAPMÿ8Pÿe<8MMhelh
`ÿ
`eDZY}h
`CZ[Cÿ
`DZ[Cÿ
`CZ}[}ÿ
`eCl|h
`ƒ?M=>ÿA?PR=RVMÿe<8MMhÿ;APÿ8PQ=R?PTÿML?PA
`eDBlh
`ÿ
`YB[}ÿ
`DBlDÿ
`DB~lÿ
`CBCÿ
`e[BCh
`W=<U9AQÿA?PR=RVMÿe<8MMhÿ;APÿ8PQ=R?PTÿML?PAÿ
`eDBlh
`YB[lÿ
`DBlCÿ
`DB~Cÿ
`CBdÿ
`e[BCh
`W=S=QARQÿ;APÿ8PQ=R?PTÿML?PAe}h
`[Bl}ÿ
`ÿ
`ÿÿ
`ÿÿ
`[B|[ÿ
`[B}dÿ
`[B}[ÿ
`:SAP?VAÿRUX@APÿ8Oÿ8PQ=R?PTÿML?PAM
`8U9M9?RQ=RV
`ÿ|d}Z[~ÿ|d}Z[~ÿ|YZlCDÿ|d|Z}}lÿ|d[Z}l~ÿY[ZCldÿ
`Y
`
` 



           


`  
`
`Mylan Ex.1069
`Mylan v. Sanofi - IPR2018-00176
`
`

`

`
` !"ÿ#$%ÿ&%'"ÿ%()%)ÿ'()ÿ'*ÿ!+ÿ,%-%./%"ÿ012
`
` 



           


`   
`ÿÿ
`ÿ
`ÿ
`ÿ3440516ÿ3440ÿ3443ÿ3441ÿ3444ÿ1777536ÿ
`ÿÿ
`ÿ8ÿÿÿ9ÿÿÿ9ÿÿÿ9ÿÿÿ9ÿÿÿ9ÿÿÿ
`ÿÿ
`5:(ÿ.:;;:!(*2ÿ%<-%=#ÿ+!"ÿ#$%ÿ(>./%"ÿ!+ÿ!"):('"&ÿ*$'"%*2ÿ
`ÿ
`?$:-$ÿ:*ÿ:(ÿ#$!>*'()*2ÿ'()ÿ#$%ÿ=%"ÿ*$'"%ÿ)'#'6ÿ
`ÿÿ
`ÿA';'(-%ÿ*$%%#ÿ)'#'B
`ÿ
`ÿ
`ÿÿ
`ÿÿÿÿ
`ÿÿÿÿ
`ÿÿÿÿ
`ÿÿÿÿ
`ÿÿÿÿ
`ÿÿÿÿ
`CDEFGHIÿJKLGMKNOPQ
`ÿ
`RSTÿ
`PUVÿ
`OSWXQ
`OUYUZ[Q
`OUYTVVQ
`OXYVUWQ
`\EDL]EM^YÿLNKHMÿKH_ÿ]`aGLb]HMYÿH]M
`ÿ
`ZYXTWÿ
`[YUWTÿ
`[Y[ZZÿ
`ZYR[Tÿ
`RY[VSÿ
`RY[VPÿ
`cDMKNÿKdd]Md
`ÿWZYPXUÿXSYXRRÿWUYTRWÿWVYXW[ÿ[XYUSWÿ
`[UYZRSÿ
`eDHIfM]Ebÿ_]gMORQ
`ÿ
`WYVRSÿ
`WYUZSÿ
`UYRSRÿ
`[YPZXÿ
`SYXUPÿ
`PY[WRÿ
`hMi]EÿNDHIfM]EbÿNGKgGNGMG]d
`ÿ
`PYRZWÿ
`ZYWPUÿ
`PYVSRÿ
`RYXXZÿ
`PYVV[ÿ
`ZYV[[ÿ
`j]Mÿ_]gMOSQ
`ÿ
`[YVSSÿ
`WYVPTÿ
`WY[ZXÿ
`VYUVZÿUWYUWWÿ
`UXYXRTÿ
`kGHDEGM^ÿGHM]E]dMdÿGHÿH]MÿKdd]MdÿDlÿJDHdDNG_KM]_
`dagdG_GKEG]d
`ÿ
`XUTÿ
`UPRÿ
`UZVÿ
`VUWÿ
`UYTXVÿ
`UY[PTÿ
`mbDEMGnKgN]ÿLE]l]EE]_ÿd]JaEGMG]d
`ÿ
`oÿ
`SVÿ
`XTTÿ
`XRXÿ
`WXZÿ
`oÿ
`pMDJFiDN_]Edqÿ]`aGM^
`ÿUWYU[[ÿUTY[W[ÿ UUYWWZÿUXYTXUÿUTYZPUÿ
`UTYWRUÿ
`ÿs#$%"ÿ!=%"'#:(tÿ)'#'B
`rKLGMKNÿdMDJFOVQ
`ÿ
`WYR[Pÿ
`WYSVVÿ
`WYVURÿ
`WYSSTÿ
`WYSPVÿ
`[YRUVÿ
`ÿÿ
`ÿÿÿÿ
`ÿÿÿÿ
`ÿÿÿÿ
`ÿÿÿÿ
`ÿÿÿÿ
`ÿÿÿÿ
`rKLGMKNÿ]uL]H_GMaE]d
`ÿ
`UYTZWÿ
`SWPÿ
`UYTTTÿ
`UYX[Zÿ
`UYZRTÿ
`R[Pÿ
`v]d]KEJiÿKH_ÿ_]w]NDLb]HMÿ]uL]Hd]d
`ÿ
`WYPSWÿ
`XYVX[ÿ
`WY[XTÿ
`WY[SUÿ
`WY[RVÿ
`UY[RZÿ
`xDNNKEÿKbDaHMdÿLEDwG_]_ÿlDEÿJDHw]HG]HJ]ÿDHN^ÿKH_ÿKE]ÿMEKHdNKM]_ÿKMÿMi]ÿjDDHÿya^GHIÿvKM]ÿGHÿ]ll]JMÿDHÿx]J]bg]EÿWUYÿXTTWÿOzÿU{TTÿ|ÿ}ÿU{XZVRQ{
`OUQ
`ci]ÿmw]HMGdÿrDHdDNG_KM]_ÿ~GHKHJGKNÿpMKM]b]HMdÿJDHdDNG_KM]ÿD]JidMÿlEDbÿx]J]bg]EÿUZYÿUVVV{
`OXQ
`\E]l]EE]_ÿE]baH]EKMGDHÿJDHdGdMdÿDlÿLK^b]HMdÿ€GMiÿE]dL]JMÿMDÿOKQÿ\E]l]EE]_ÿpiKE]dÿp]EG]dÿmYÿOgQÿmbDEMGnKgN]ÿ\E]l]EE]_ÿp]JaEGMG]dYÿOJQÿ\KEMGJGLKMGHIÿpiKE]dÿp]EG]dÿmÿKH_
`OWQ
`O_QÿrKLGMKNÿ`aGM^ÿjDM]d{
`rDbbDHÿdiKE]dÿJDHdGdMÿDlÿhE_GHKE^ÿpiKE]dÿ‚m{‚
`O[Q
`ci]ÿ_GwG_]H_ÿlDEÿXTTWÿ€GNNÿg]ÿLEDLDd]_ÿKMÿMi]ÿmHHaKNÿƒ]H]EKNÿk]]MGHIÿGHÿmLEGNÿXTT[ÿKH_ÿGdÿdag„]JMÿMDÿKLLEDwKNÿg^ÿdiKE]iDN_]Ed{
`OZQ
`CDEFGHIÿJKLGMKNÿGdÿ_]lGH]_ÿKdÿMDMKNÿJaEE]HMÿKdd]MdÿbGHadÿMDMKNÿJaEE]HMÿNGKgGNGMG]d{
`OPQ
`ÿÿÿ
`eDHIfM]Ebÿ_]gMÿGHJNa_]dÿMi]ÿ_]gMÿE]NKMGHIÿMDÿJKLGMKNGn]_ÿN]Kd]dÿgaMÿ_D]dÿHDMÿGHJNa_]ÿMi]ÿJaEE]HMÿLDEMGDHÿDlÿNDHIfM]Ebÿ_]gM{
`ORQ
`j]Mÿ_]gMÿGdÿ_]lGH]_ÿKdÿgKHFÿDw]E_EKlMdYÿJaEE]HMÿLDEMGDHÿDlÿNDHIfM]Ebÿ_]gMYÿdiDEMfM]EbÿKH_ÿNDHIfM]EbÿgDEED€GHIdÿbGHadÿJKdiYÿdiDEMfM]Ebÿ_]LDdGMdÿKH_ÿbKEF]MKgN]ÿd]JaEGMG]d{
`OSQ
`rDHdGdMGHIÿDlÿDE_GHKE^ÿdiKE]dYÿJKLGMKNÿ]`aGM^ÿHDM]dYÿLE]l]E]HJ]ÿdiKE]dÿKH_ÿLKEMGJGLKMGHIÿdiKE]d{ÿp]]ÿjDM]ÿUTÿMDÿMi]ÿmw]HMGdÿrDHdDNG_KM]_ÿ~GHKHJGKNÿpMKM]b]HMdÿGHJNa_]_ÿGH
`OVQ
`MiGdÿmHHaKNÿv]LDEM{
`
` !"ÿ#$%ÿ&%'"ÿ%()%)ÿ'()ÿ'*ÿ!+ÿ,%-%./%"ÿ012
`ÿ
`ÿ
`ÿ3440516ÿ3440ÿ3443ÿ3441ÿ3444ÿ1777536ÿ
`ÿÿ
`ÿ8ÿÿÿ9ÿÿÿ9ÿÿÿ9ÿÿÿ9ÿÿÿ9ÿÿÿ
`ÿÿ
`5:(ÿ.:;;:!(*2ÿ%<-%=#ÿ+!"ÿ#$%ÿ(>./%"ÿ!+ÿ!"):('"&ÿ*$'"%*2ÿ
`ÿ
`?$:-$ÿ:*ÿ:(ÿ#$!>*'()*2ÿ'()ÿ#$%ÿ=%"ÿ*$'"%ÿ)'#'6ÿ
`ÿÿ
`ÿ
`ÿ
`
`…†‡†ÿˆ‰‰Šÿ)'#'5146
`ÿÿ
`ÿÿ
`ÿÿ
`ÿ
`ÿÿ
`ÿÿ
`ÿÿ
`‹(-!.%ÿ*#'#%.%(#ÿ)'#'B
`ÿÿ
`ÿÿ
`ÿÿ
`ÿ
`ÿÿ
`ÿÿ
`ÿÿ
`j]MÿdKN]d
`ÿXUYXU[ÿUPYS[UÿURYP[VÿUPYPTVÿUPYUXUÿ
`UXY[UZÿ
`rDfLEDbDMGDHÿGHJDb]
`ÿ
`WURÿ
`XZXÿ
`ÿ
`UPUÿ
`UZUÿÿ
`ÿÿ
`hL]EKMGHIÿGHJDb]ÿONDddQ
`ÿ
`ZYTPWÿ
`[YTXTÿ
`OXYVVTQ
`WYRVRÿ
`XYR[Xÿ
`URXÿ
`ŒHJDb]ÿMKu]d
`ÿ
`OUYUURQ
`OSSRQ
`ORXSQ
`OUYXWVQ
`ORRXQ
`UUSÿ
`kGHDEGM^ÿGHM]E]dMd
`ÿ
`OWPQ
`OXVQ
`OUVQ
`O[WQ
`O[VQ
`OUSQ
`j]MÿGHJDb]ÿlEDbÿJDHMGHaGHIÿDL]EKMGDHd
`ÿ
`WYTUPÿ
`XYWV[ÿ
`OWYZTVQ
`UYRSSÿ
`VSWÿ
`RSÿ
`j]MÿGHJDb]ÿONDddQÿg]lDE]ÿE]baH]EKMGDHÿDlÿLE]l]EE]_
`d]JaEGMG]dÿJNKddGlG]_ÿGHÿdMDJFiDN_]Edqÿ]`aGM^
`ÿ
`XYPUTÿ
`XYTRXÿ
`OWYTXPQ
`UYVZTÿ
`SUPÿ
`OPXWQ
`v]baH]EKMGDHÿDlÿLE]l]EE]_ÿd]JaEGMG]dÿJNKddGlG]_ÿGH
`dMDJFiDN_]Edqÿ]`aGM^O[Q
`ÿ
`OZZQ
`O[[Q
`O[Q
`OZRQ
`ORSQ
`OSZQ
`j]MÿGHJDb]ÿONDddQÿoÿJDbbDHÿdiKE]iDN_]Ed
`ÿ
`XYZZZÿ
`XYTXSÿ
`OWYTWTQ
`UYSVWÿ
`RWSÿ
`ORTSQ
`yKdGJÿ]KEHGHIdÿONDddQÿoÿJDHMGHaGHIÿDL]EKMGDHdÿo ÿ
`W{RRÿ
`X{VVÿ
`OR{SPQ
`X{USÿ
`U{UZÿ
`OT{TUQ
`
` 



           


`  
`
`Mylan Ex.1069
`Mylan v. Sanofi - IPR2018-00176
`
`

`

` !! "ÿ$%&'(% )*('
`
` 



           


`   
`+,)-.(*ÿ(&'","/$ÿ0) $$1ÿ2ÿ ".,"-,"/ÿ 3('&., "$ÿ2
` !! "ÿ$%&'(% )*('
`ÿ
`4567ÿ
`859:ÿ
`85;<ÿ
`;5;4ÿ
`0=5=;1
`065:<1
`0<56:1
`>&$,ÿ(&'","/$ÿ0) $$1ÿ3('ÿ$%&'(ÿ2ÿ !! "ÿ$. ?ÿ
`4587ÿ
`857:ÿ
`8549ÿ
`=59@ÿ
`0=59;1
`+,)-.(*ÿ(&'","/$ÿ0) $$1ÿ3('ÿ$%&'(ÿ2ÿ !! "ÿ$. ?ÿ
`0<56:1
`458@ÿ
`8576ÿ
`8546ÿ
`=594ÿ
`0=59;1
`@
`BCDÿEFGÿHGIDÿGJKGKÿIJKÿILÿCMÿNGOGPQGDÿRST
`ÿÿ
`ÿ
`ÿUVVRWSXÿUVVRÿUVVUÿUVVSÿUVVVÿSYYYWUX
`ÿÿ
`ÿ Zÿÿÿ [ÿÿÿ [ÿÿÿ [ÿÿÿ [ÿÿÿ[ÿÿ
`ÿÿ
`W\JÿP\]]\CJLTÿG^OG_EÿMCDÿEFGÿJ`PQGDÿCMÿCDK\JIDHÿLFIDGLTÿ
`ÿ
`aF\OFÿ\Lÿ\JÿEFC`LIJKLTÿIJKÿEFGÿ_GDÿLFIDGÿKIEIXÿ
`ÿÿ
`ÿbI]IJOGÿLFGGEÿKIEIc
`ÿ
`ÿÿÿÿ
`ÿÿÿÿ
`ÿÿÿÿ
`ÿÿÿÿ
`ÿÿÿÿ
`ÿÿÿÿ
`d '?,"/ÿ&3,.&)0<1
`ÿ
`;e=;9ÿ
`:=9ÿ
`;@;ÿ
`06:@1
`4e:;:ÿ
`4e=9@
`f' 3('.geÿ3)&".ÿ&"*ÿ(h-,3!(".eÿ"(.
`ÿ
`7e@8=ÿ
`@e4=4ÿ
`@e46:ÿ
`@e@89ÿ
`@e<;6ÿ
`:e864
`i .&)ÿ&$$(.$
`ÿ
`@8e664ÿ
`44e977ÿ
`46e=:4ÿ
`@:e7=9ÿ
`78e796ÿ78e889
`j "/k.('!ÿ*(l.061
`ÿ
`4e96:ÿ
`4e;7:ÿ
`;e6:6ÿ
`@e769ÿ
`<e<74ÿ
`<e@46
`m.%('ÿ) "/k.('!ÿ),&l,),.,($
`ÿ
`:e77=ÿ
`<e6:6ÿ
`:e@:4ÿ
`:e<@8ÿ
`:e;76ÿ
`9e446
`n," ',.gÿ,".('($.$ÿ,"ÿ"(.ÿ&$$(.$ÿ oÿ "$ ),*&.(*
`$-l$,*,&',($
`ÿ
`884ÿ
`;66ÿ
`;77ÿ
`8:6ÿ
`9<:ÿ
`;e@:7
`p! '.,q&l)(ÿ3'(o(''(*ÿ$(-',.,($
`ÿ
`ÿÿ
`rÿ
`:9ÿ
`8==ÿ
`868ÿ
`487
`s. ?% )*('$tÿ(h-,.g
`ÿ
`;@e<:@ÿ
`;7e6:@ÿ
`;6e7:8ÿ
`;6e87:ÿ;6e<=4
`;:e@96ÿ
`u&3,.&)ÿ$. ?091
`ÿ
`4e6@<ÿ
`4e:99ÿ
`4e9;6ÿ
`4e::=ÿ
`@e6;9ÿ
`4e:<9
`ÿwxyxÿz{{|ÿ}EFGDÿC_GDIE\J~ÿKIEIc
`v-!l('ÿ oÿ '*,"&'gÿ$%&'($ÿ -.$.&"*,"/
`ÿ :=8e894ÿ :=8e894ÿ699e@6@ÿ697e<88ÿ6:7e:69ÿ669e:;<
`ÿÿÿÿ
`ÿÿÿÿ
`ÿÿÿÿ
`ÿÿÿÿ
`ÿÿÿÿ
`ÿÿÿÿ
`u&3,.&)ÿ(3("*,.-'($
`ÿ
`;e=74ÿ
`:4<ÿ
`;e===ÿ
`;e8@7ÿ
`;e76=ÿ
`:66
`€($(&'%ÿ&"*ÿ*(() 3!(".ÿ(3("$($
`ÿ
`4e<=6ÿ
`8e:<4ÿ
`4e;@4ÿ
`8e:9<ÿ
`8e94<ÿ
`@e9@@
`+,,*("*ÿ3('ÿ '*,"&'gÿ$%&'(071
`ÿ
`rÿ
`rÿ
`=56=ÿ
`=57:ÿ
`=57=ÿ
`=5@7
`v(.ÿ*(l.0:1
`ÿ
`@e9;@ÿ
`4e9=;ÿ
`4e@<:ÿ
`6e4;6ÿ
`:e;6@ÿ;;e@:@
`+ ))&'ÿ&! -".$ÿ3' ,*(*ÿo 'ÿ "(",("(ÿ ")gÿ&"*ÿ&'(ÿ.'&"$)&.(*ÿ&.ÿ.%(ÿv "ÿ>-g,"/ÿ€&.(ÿ,"ÿ(oo(.ÿ "ÿ+((!l('ÿ4;eÿ8==8ÿ0‚ÿ;5==ÿƒÿ„ÿ;5879615
`0;1
`… 'ÿ…'("%ÿ†ppfÿ3-'3 $($eÿ.%(ÿp(".,$ÿ "$ ),*&.(*ÿ…,"&",&)ÿs.&.(!(".$ÿ "$ ),*&.(ÿ‡ (%$.ÿo' !ÿ+((!l('ÿ;7eÿ;9995ÿ… 'ÿ…'("%ÿ†ppfÿ3-'3 $($eÿ.%(ÿp(".,$
`
`081
`u "$ ),*&.(*ÿ…,"&",&)ÿs.&.(!(".$ÿo 'ÿ;99:ÿ* ÿ" .ÿ "$ ),*&.(ÿ&"gÿ ".',l-., "$ÿo' !ÿ‡ (%$.5ÿ… 'ÿˆ5s5ÿ†ppfÿ3-'3 $($eÿ.%(ÿo '!&., "ÿ oÿp(".,$ÿ‰&$ÿ& -".(*ÿo 'ÿ&$ÿ&
`'(('$(ÿ&h-,$,., "ÿ&$ÿ oÿ+((!l('ÿ;7eÿ;9995
`€(!-"('&., "ÿ oÿ3'(o(''(*ÿ$(-',.,($ÿ)&$$,o,(*ÿ,"ÿs. ?% )*('$tÿ(h-,.gÿ "$,$.ÿ oÿ3&g!(".$ÿ‰,.%ÿ'($3(.ÿ. ÿ0&1ÿf'(o(''(*ÿs%&'($ÿs(',($ÿpeÿ0l1ÿf&'.,,3&.,"/ÿs%&'($ÿs(',($ÿp
`041
`&"*ÿ01ÿu&3,.&)ÿŠh-,.gÿv .($5
`u !! "ÿ$%&'($ÿ "$,$.ÿ oÿm'*,"&'gÿs%&'($ÿ‹p‹5
`0@1
`i%(ÿ*,,*("*ÿo 'ÿ8==4ÿ‰,))ÿl(ÿ3' 3 $(*ÿ&.ÿ.%(ÿp""-&)ÿ†("('&)ÿn((.,"/ÿ,"ÿp3',)ÿ8==@ÿ&"*ÿ,$ÿ$-lŒ(.ÿ. ÿ&33' &)ÿlgÿ$%&'(% )*('$5
`071
`d '?,"/ÿ&3,.&)ÿ,$ÿ*(o,"(*ÿ&$ÿ. .&)ÿ-''(".ÿ&$$(.$ÿ!,"-$ÿ. .&)ÿ-''(".ÿ),&l,),.,($5
`0<1
`j "/k.('!ÿ*(l.ÿ,")-*($ÿ.%(ÿ*(l.ÿ'()&.,"/ÿ. ÿ&3,.&),q(*ÿ)(&$($ÿl-.ÿ* ($ÿ" .ÿ,")-*(ÿ.%(ÿ-''(".ÿ3 '., "ÿ oÿ) "/k.('!ÿ*(l.5
`061
`v(.ÿ*(l.ÿ,$ÿ*(o,"(*ÿ&$ÿl&"?ÿ ('*'&o.$eÿ-''(".ÿ3 '., "ÿ oÿ) "/k.('!ÿ*(l.eÿ$% '.k.('!ÿ&"*ÿ) "/k.('!ÿl '' ‰,"/$ÿ!,"-$ÿ&$%eÿ$% '.k.('!ÿ*(3 $,.$ÿ&"*ÿ!&'?(.&l)(ÿ$(-',.,($5
`0:1
`u "$,$.,"/ÿ oÿ '*,"&'gÿ$%&'($eÿ&3,.&)ÿ(h-,.gÿ" .($eÿ3'(o('("(ÿ$%&'($ÿ&"*ÿ3&'.,,3&.,"/ÿ$%&'($5ÿs((ÿv .(ÿ;=ÿ. ÿ.%(ÿp(".,$ÿu "$ ),*&.(*ÿ…,"&",&)ÿs.&.(!(".$ÿ,")-*(*ÿ,"
`091
`.%,$ÿp""-&)ÿ€(3 '.5
`0;=1+,$ ".,"-(*ÿ 3('&., "$ÿ oÿ8==4ÿ%&(ÿl(("ÿ'($.&.(*ÿ,"ÿ8==8ÿ&"*ÿ8==;ÿ*,$ ".,"-(*ÿ 3('&., "$ÿ oÿ8==8ÿ&"*ÿ8==;ÿ%&(ÿl(("ÿ'($.&.(*ÿ,"ÿ8==;ÿ&"*ÿ8===ÿ$-%ÿ,"o '!&., "ÿ,$
`7
`" .ÿ'(&$ "&l)gÿ&&,)&l)(ÿo 'ÿ3', 'ÿg(&'$5ÿ+,$ ".,"-(*ÿ 3('&., "$ÿ -'',"/ÿ,"ÿ;999ÿ‰('(ÿ*,$) $(*ÿ,"ÿ;9995
`ÿŽ^OFIJ~GÿIEGÿJMCDPIE\CJÿ
`ÿÿÿÿÿÿÿÿ… 'ÿg -'ÿ "(",("(eÿ.%,$ÿp""-&)ÿ€(3 '.ÿ ".&,"$ÿ.'&"$)&., "$ÿ oÿ('.&,"ÿ(-' ÿ&! -".$ÿ,". ÿˆ5s5ÿ* ))&'$5ÿˆ")($$ÿ .%('‰,$(ÿ,"*,&.(*e
`* ))&'ÿ&! -".$ÿ%&(ÿl(("ÿ.'&"$)&.(*ÿo' !ÿ(-' $ÿ&.ÿ.%(ÿ'&.(ÿ oÿ‚ÿ;5==ÿƒÿ„ÿ;58796eÿ.%(ÿv "ÿ>-g,"/ÿ€&.(ÿo 'ÿ.%(ÿ(-' ÿ "ÿ+((!l('ÿ4;eÿ8==45
`i%(ÿ‹v "ÿ>-g,"/ÿ€&.(‹ÿ,$ÿ.%(ÿ" "ÿl-g,"/ÿ'&.(ÿ,"ÿv(‰ÿ‘ '?ÿu,.gÿo 'ÿ&l)(ÿ.'&"$o('$ÿ,"ÿo '(,/"ÿ-''(",($ÿ&$ÿ('.,o,(*ÿo 'ÿ-$. !$
`3-'3 $($ÿlgÿ.%(ÿ…(*('&)ÿ€($('(ÿ>&"?ÿ oÿv(‰ÿ‘ '?5ÿi%,$ÿ* ($ÿ" .ÿ!(&"ÿ.%&.ÿ‰(ÿ&.-&))gÿ "('.(*ÿ.%($(ÿ&! -".$ÿ,". ÿˆ5s5ÿ* ))&'$ÿ&.ÿ.%&.
`'&.(eÿ&"*ÿg -ÿ$% -)*ÿ" .ÿ&$$-!(ÿ.%&.ÿ.%(gÿ -)*ÿ%&(ÿl(("ÿ "('.(*ÿ&.ÿ.%&.ÿ 'ÿ&"gÿ .%('ÿ'&.(5
`
` 



           


`  
`
`Mylan Ex.1069
`Mylan v. Sanofi - IPR2018-00176
`
`

`

`ÿÿÿÿÿÿÿÿ !"#$"%$&'()ÿ&(ÿ$*+ÿ+,#*%(-+ÿ.%$+ÿ/+$0++(ÿ$*+ÿ+".'ÿ%(1ÿ$*+ÿ2343ÿ1'!!%.ÿ0&!!ÿ%55+#$ÿ$*+ÿ2343ÿ1'!!%.ÿ6.&#+ÿ'5ÿ'".ÿ78+.&#%(ÿ9+6')&$%.:
`
` 



           


`   
`4*%.+)ÿ;794)<ÿ'(ÿ$*+ÿ=+0ÿ>'.?ÿ4$'#?ÿ@,#*%(-+ÿ%(1ÿ$*+ÿ2343ÿ1'!!%.ÿA%!"+ÿ'5ÿ%(:ÿ1&A&1+(1)ÿ0+ÿ8%:ÿ1+#!%.+3
`ÿÿÿÿÿÿÿÿB*+ÿ5'!!'0&(-ÿ$%/!+ÿ)*'0)ÿ$*+ÿ+".'C2343ÿ1'!!%.ÿ+,#*%(-+ÿ.%$+ÿ5'.ÿDEEEÿ$*.'"-*ÿ +/."%.:ÿFGGHÿ/%)+1ÿ'(ÿ$*+ÿ=''(ÿI":&(-ÿJ%$+
`+,6.+))+1ÿ&(ÿ+".')ÿ6+.ÿ2343ÿ1'!!%.3
`ÿ
`KLMLNOLPÿRSNTUVWLÿXUOLÿYVZ[\]UO^[Vÿ
`ÿabL\UWLÿ
`ÿ_L\^[P`LVPÿ
`\UOL
`\UOLcdeÿf^WTÿg[h
`ÿÿ
`i[VOT
`ÿÿ
`ÿÿ
`ÿÿ
`ÿÿ
`ÿÿ
`ÿÿ
`ÿÿ
`ÿÿ
`@".'C2343ÿ1'!!%.;F<
`
` +/."%.:ÿFGGH
`ÿ
`jG3kGÿ
`jG3lEÿjG3kGÿ jG3lk
`m%("%.:ÿFGGH
`ÿ
`G3kGÿ
`G3lEÿ
`G3kDÿ
`G3lk
`9+#+8/+.ÿFGGn
`ÿ
`G3lEÿ
`G3kDÿ
`G3knÿ
`G3lE
`='A+8/+.ÿFGGn
`ÿ
`G3knÿ
`G3koÿ
`G3kkÿ
`G3kn
`p#$'/+.ÿFGGn
`ÿ
`G3kqÿ
`G3koÿ
`G3kqÿ
`G3ko
`ÿrLU\
`4+6$+8/+.ÿFGGn
`ÿ
`G3kqÿ
`G3kEÿ
`G3EFÿ
`G3kq
`ÿÿÿÿ
`ÿÿÿÿ
`ÿÿÿÿ
`ÿÿÿÿ
`ÿÿ
`ÿÿ
`ÿÿ
`ÿÿ
`@".'C2343ÿ1'!!%.;F<
`FGGn
`ÿ
`jG3lEÿ
`jG3kkÿjG3Elÿ jG3lE
`FGGF
`ÿ
`G3Eoÿ
`D3Goÿ
`D3Dqÿ
`G3Eo
`FGGD
`ÿ
`D3DFÿ
`D3DFÿ
`D3DEÿ
`D3Go
`FGGG
`ÿ
`D3Glÿ
`D3GEÿ
`D3FDÿ
`G3El
`DEEE
`ÿ
`G3EEÿ
`G3EHÿ
`D3GGÿ
`G3ko
`B*+ÿ%A+.%-+ÿ.%$+ÿ'5ÿ$*+ÿ=''(ÿI":&(-ÿ.%$+ÿ5'.ÿ+".')ÿ'(ÿ$*+ÿ!%)$ÿ/")&(+))ÿ1%:ÿ'5ÿ+%#*ÿ8'($*ÿ1".&(-ÿ$*+ÿ.+!+A%($ÿ6+.&'13
`;D<
`q
`p.&-&(%!!:ÿ6"/!&)*+1ÿ%)ÿ2343ÿ1'!!%.C+".'3
`;F<
`ÿX^stÿuUNO[\sÿ
`ÿÿÿÿÿÿÿÿv86'.$%($ÿ5%#$'.)ÿ$*%$ÿ#'"!1ÿ#%")+ÿ%#$"%!ÿ.+)"!$)ÿ$'ÿ1&55+.ÿ8%$+.&%!!:ÿ5.'8ÿ'".ÿ+,6+#$%$&'()ÿ%.+ÿ1&)#!')+1ÿ&(ÿ$*&)ÿ7(("%!ÿJ+6'.$w
`&(#!"1&(-ÿ0&$*'"$ÿ!&8&$%$&'(ÿ$*')+ÿ1+)#.&/+1ÿ"(1+.ÿxy%"$&'(%.:ÿ4$%$+8+($ÿJ+-%.1&(-ÿ '.0%.1z{''?&(-ÿ4$%$+8+($)xÿ%(1ÿ$*+ÿ5'!!'0&(-ÿ.&)?
`5%#$'.)3ÿv(ÿ%11&$&'(ÿ$'ÿ$*+ÿ.&)?)ÿ!&)$+1ÿ/+!'0wÿ0+ÿ8%:ÿ/+ÿ)"/|+#$ÿ$'ÿ'$*+.ÿ8%$+.&%!ÿ.&)?)ÿ$*%$ÿ%.+ÿ('$ÿ#"..+($!:ÿ?('0(ÿ$'ÿ")ÿ'.ÿ$*%$ÿ0+ÿ1++8
`&88%$+.&%!ÿ%$ÿ$*&)ÿ$&8+3
`}~€ÿ}‚ƒ„…‚†ÿ…‡ÿ‡ˆ‰ÿŠˆ~‹‚
`YZÿ\LsLU\NTÿUVPÿPLbLM[Œ]LVOÿP[LsÿV[Oÿ^LMPÿVLhÿŒ\[PŽNOsÿOTUOÿUNT^LbLÿN[]]L\N^UMÿsŽNNLssÿhLÿh^MMÿV[Oÿ\LUM^Lÿ[Ž\ÿ‘Žs^VLssÿW\[hOT
`LSŒLNOUO^[Vs’
`ÿÿÿÿÿÿÿÿ{&?+ÿ'$*+.ÿ8%|'.ÿ6*%.8%#+"$&#%!ÿ#'86%(&+)wÿ0+ÿ1+A'$+ÿ)"/)$%($&%!ÿ.+)'".#+)ÿ$'ÿ.+)+%.#*ÿ%(1ÿ1+A+!'68+($ÿ0&$*ÿ$*+ÿ-'%!ÿ'5
`8%&($%&(&(-ÿ%ÿ#'($&("'")ÿ5!'0ÿ'5ÿ&(('A%$&A+ÿ6.'1"#$)ÿ$*.'"-*ÿ'".ÿ.+)+%.#*ÿ%(1ÿ1+A+!'68+($ÿ6&6+!&(+ÿ$'ÿ8%.?+$&(-ÿ%66.'A%!3ÿ '.ÿ%ÿ("8/+.
`'5ÿ.+%)'()wÿ&(#!"1&(-ÿ$*+ÿ!+(-$*:ÿ6.'1"#$ÿ1+A+!'68+($ÿ6.'#+))wÿ$+#*('!'-&#%!ÿ#*%!!+(-+)wÿ%(1ÿ&($+()+ÿ#'86+$&$&'(wÿ0+ÿ#%(('$ÿ%))".+ÿ:'"
`$*%$ÿ%(:ÿ'5ÿ'".ÿ6.'1"#$)ÿ#"..+($!:ÿ"(1+.ÿ1+A+!'68+($wÿ'.ÿ5'.ÿ0*&#*ÿ0+ÿ8%:ÿ/+-&(ÿ$*+ÿ1+A+!'68+($ÿ6.'#+))wÿ0&!!ÿ/+ÿ8%.?+$+1ÿ%(1ÿ%#*&+A+
`)"/)$%($&%!ÿ#'88+.#&%!ÿ)"##+))3ÿv5ÿ0+ÿ%.+ÿ('$ÿ%/!+ÿ$'ÿ8%&($%&(ÿ%ÿ#'($&("'")ÿ5!'0ÿ'5ÿ)"##+))5"!ÿ(+0ÿ6.'1"#$)ÿ$'ÿ#'A+.ÿ'".ÿ)"/)$%($&%!
`.+)+%.#*ÿ#')$)ÿ%(1ÿ.+6!%#+ÿ)%!+)ÿ$*%$ÿ%.+ÿ!')$ÿ%)ÿ'!1+.ÿ6.'1"#$)ÿ%66.'%#*ÿ$*+ÿ+(1ÿ'5ÿ$*+&.ÿ#'88+.#&%!ÿ!&5+ÿ#:#!+)ÿ'.ÿ%.+ÿ1&)6!%#+1ÿ/:
`#'86+$&(-ÿ6.'1"#$)ÿ'.ÿ$*+.%6&+)wÿ0+ÿ0&!!ÿ('$ÿ/+ÿ%/!+ÿ$'ÿ8%&($%&(ÿ'".ÿ#"..+($ÿ!+A+!)ÿ'5ÿ)%!+)ÿ'.ÿ'6+.%$&(-ÿ.+)"!$)3
`_UOLVOÿŒ\[OLNO^[Vÿ]UÿŒ\[bLÿ^VLZZLNO^bL’ÿg[ssÿ[ZÿLZZLNO^bLÿŒUOLVOÿŒ\[OLNO^[Vÿ[Vÿ[VLÿ[\ÿ][\LÿŒ\[PŽNOsÿN[ŽMPÿ\LsŽMOÿ^VÿM[sOÿsUMLsÿO[
`N[]ŒLO^VWÿŒ\[PŽNOsÿUVPÿVLWUO^bLMÿUZZLNOÿ[Ž\ÿsUMLsÿUVPÿ[ŒL\UO^VWÿ\LsŽMOs’
`
` 



           


`  
`
`Mylan Ex.1069
`Mylan v. Sanofi - IPR2018-00176
`
`

`

`ÿÿÿÿÿÿÿÿ !ÿ"#$%ÿ&'(!ÿ'))*+!,ÿ-".%ÿ".ÿ'.!ÿ*+/!$0!,ÿ1$,!.%ÿ$12!."10ÿ)'3!$30ÿ.!*'3+$4ÿ3"ÿ"1.ÿ).",1/305ÿ61.+$4ÿ3&!ÿ)!.+",ÿ+$ÿ#&+/&ÿ'ÿ7.'$,8$'2!
`
` 



           


`   
`)&'.2'/!13+/'*ÿ).",1/390ÿ'/3+(!ÿ+$4.!,+!$3ÿ+0ÿ017:!/3ÿ3"ÿ)'3!$3ÿ)."3!/3+"$ÿ'$,ÿ'$;ÿ'))*+/'7*!ÿ)!.+",ÿ"-ÿ.!41*'3".;ÿ!</*10+(+3;%ÿ3&!ÿ).",1/3
`2';ÿ7!ÿ017:!/3ÿ3"ÿ/"2)!3+3+"$ÿ"$*;ÿ-."2ÿ'*3!.$'3+(!ÿ3&!.')+!0ÿ'$,ÿ'*3!.$'3+(!ÿ).",1/30ÿ10+$4ÿ,+--!.!$3ÿ'/3+(!ÿ+$4.!,+!$305ÿ="**"#+$4
`!<)+.'3+"$ÿ"-ÿ)'3!$3ÿ)."3!/3+"$ÿ-".ÿ3&!ÿ'/3+(!ÿ+$4.!,+!$3%ÿ&"#!(!.%ÿ'ÿ7.'$,8$'2!ÿ).",1/3ÿ+0ÿ*+>!*;ÿ3"ÿ-'/!ÿ',,+3+"$'*ÿ/"2)!3+3+"$ÿ3&."14&ÿ3&!
`!$3.;ÿ+$3"ÿ3&!ÿ2'.>!3ÿ"-ÿ?4!$!.+/?ÿ).",1/30ÿ/"$3'+$+$4ÿ3&!ÿ0'2!ÿ'/3+(!ÿ+$4.!,+!$35ÿ@$ÿ3&!ÿA$+3!,ÿB3'3!0%ÿ+-ÿ01/&ÿ'ÿ).",1/3ÿ,!2"$03.'3!0
`?7+"!C1+('*!$/!%?ÿ".ÿ3&!ÿ'7+*+3;ÿ3"ÿ2'+$3'+$ÿ7*"",ÿ*!(!*0ÿ"-ÿ'/3+(!ÿ+$4.!,+!$3ÿ!C1+('*!$3ÿ3"ÿ3&!ÿ7.'$,8$'2!ÿ).",1/3%ÿ+3ÿ2';ÿ7!ÿ'))."(!,ÿ-".
`2'.>!3+$4ÿ#+3&"13ÿ3&!ÿ/"03*;ÿ'$,ÿ3+2!8/"$012+$4ÿ,!(!*")2!$3ÿ!--".30ÿ'$,ÿ3!03+$4ÿ.!C1+.!,ÿ-".ÿ3&!ÿ".+4+$'*ÿ7.'$,8$'2!ÿ).",1/35ÿD&!ÿ!$3.;
`"-ÿ'ÿ4!$!.+/ÿ).",1/3ÿ+$3"ÿ3&!ÿ2'.>!3ÿ3;)+/'**;ÿ+0ÿ-"**"#!,ÿ7;ÿ'ÿ01703'$3+'*ÿ,!/*+$!ÿ+$ÿ3&!ÿ7.'$,8$'2!ÿ).",1/390ÿ2'.>!3ÿ0&'.!ÿ'$,ÿ0'*!0
`.!(!$1!05ÿD&!ÿ!<3!$3ÿ3"ÿ#&+/&ÿ4!$!.+/ÿ/"2)!3+3+"$ÿ/'$ÿ7!ÿ!<)!/3!,ÿ3"ÿ'--!/3ÿ0'*!0ÿ'$,ÿ2'.4+$0ÿ"-ÿ3&!ÿ".+4+$'*ÿ7.'$,8$'2!ÿ).",1/3ÿ+$ÿ'
`4+(!$ÿ2'.>!3ÿ,!)!$,0ÿ"$ÿ01/&ÿ-'/3".0ÿ'0ÿ#&!3&!.ÿ,!2'$,ÿ-".ÿ3&!ÿ3&!.');ÿ#+**ÿ01))".3ÿ21*3+)*!ÿ).",1/!.0%ÿ3&!ÿ3+2!ÿ'$,ÿ!<)!$0!ÿ+$("*(!,
`+$ÿ"73'+$+$4ÿ2'.>!3+$4ÿ'))."('*ÿ-".ÿ3&!ÿ4!$!.+/%ÿ3&!ÿ.!*'3+(!ÿ!'0!ÿ".ÿ,+--+/1*3;ÿ"-ÿ2'$1-'/31.+$4ÿ3&!ÿ).",1/3%ÿ'$,ÿ3&!ÿ'7+*+3;ÿ"-ÿ3&!ÿ7.'$,8
`$'2!ÿ).",1/390ÿ2'$1-'/31.!.ÿ3"ÿ,!(!*")ÿ$!#ÿ".ÿ,+--!.!$3ÿ)'3!$3!,ÿ-".21*'3+"$0ÿ#+3&ÿ01703'$3+'**;ÿ+2)."(!,ÿ/&'.'/3!.+03+/0%ÿ01/&ÿ'0ÿ!'0!ÿ"-
`',2+$+03.'3+"$5
`ÿÿÿÿÿÿÿÿ@$ÿ3&!ÿ)&'.2'/!13+/'*ÿ+$,103.;%ÿ)'3!$3ÿ!<)+.'3+"$0ÿ2';ÿ'--!/3ÿ!(!$ÿ.!*'3+(!*;ÿ.!/!$3*;ÿ'))."(!,ÿ,.140%ÿ3&!ÿ'/3+(!ÿ+$4.!,+!$30ÿ"-ÿ#&+/&
`2';ÿ&'(!ÿ7!!$ÿ,+0/"(!.!,ÿ'$,ÿ)'3!$3!,ÿ*"$4ÿ7!-".!ÿ3&!ÿ,+0/"(!.;ÿ'$,ÿ'))."('*ÿ"-ÿ3&!+.ÿ10!ÿ-".ÿ0)!/+-+/ÿ3&!.')!13+/ÿ+$,+/'3+"$05ÿE"#!(!.%
`+$ÿ',,+3+"$ÿ3"ÿ)'3!$30ÿ/"(!.+$4ÿ3&!ÿ'/3+(!ÿ+$4.!,+!$3%ÿ"1.ÿ)&'.2'/!13+/'*ÿ).",1/30ÿ2';ÿ7!ÿ)."3!/3!,ÿ7;ÿ"3&!.ÿ)'3!$30%ÿ+$/*1,+$4ÿ3&"0!
`/"(!.+$4ÿ,+--!.!$3ÿ-".21*'3+"$0ÿ10!,ÿ+$ÿ3.!'32!$3%ÿ0)!/+-+/ÿ2!3&",0ÿ"-ÿ2'$1-'/31.!%ÿ2!3&",0ÿ"-ÿ',2+$+03.'3+"$%ÿ'$,ÿ0)!/+-+/ÿ+$,+/'3+"$0ÿ"-
`10!5ÿA$3+*ÿ3&!+.ÿ!<)+.'3+"$%ÿ01/&ÿ)'3!$30ÿ2';ÿ)."(+,!ÿ('.;+$4ÿ,!4.!!0ÿ"-ÿ)."3!/3+"$ÿ-".ÿ'ÿ,.14ÿ7!;"$,ÿ3&!ÿ!<)+.'3+"$ÿ"-ÿ)'3!$30ÿ/"(!.+$4
`"$*;ÿ+30ÿ'/3+(!ÿ+$4.!,+!$30%ÿ-".ÿ!<'2)*!ÿ+-ÿ'$ÿ'/3+(!ÿ+$4.!,+!$3ÿ".ÿ-+$+0&!,ÿ).",1/3ÿ+0ÿ)'.3+/1*'.*;ÿ,+--+/1*3ÿ3"ÿ2'$1-'/31.!ÿ".ÿ+-ÿ2".!
`'))!'*+$4ÿ-".21*'3+"$0ÿ".ÿ2!3&",0ÿ"-ÿ',2+$+03.'3+"$ÿ)."(+,!ÿ',('$3'4!0ÿ"(!.ÿ4!$!.+/ÿ/"2)!3+3".05ÿE"#!(!.%ÿ3&!.!ÿ/'$ÿ7!ÿ$"ÿ'001.'$/!
`3&'3ÿ/"2)!3+3".0ÿ#+**ÿ$"3ÿ7!ÿ'7*!ÿ3"ÿ?,!0+4$ÿ'."1$,?ÿ01/&ÿ)'3!$30%ÿ,!(!*")ÿ'*3!.$'3+(!ÿ2!3&",0ÿ"-ÿ2'$1-'/31.!%ÿ".ÿ/.!'3!ÿ$"$8+$-.+$4+$4
`-".21*'3+"$0ÿ3&'3ÿ'.!ÿ'3ÿ*!'03ÿ'0ÿ'))!'*+$45
`ÿÿÿÿÿÿÿÿB'*!0ÿ'$,ÿ)."-+3'7+*+3;ÿ"-ÿ"1.ÿ)'3!$3!,ÿ).",1/30ÿ'*0"ÿ2';ÿ7!ÿ',(!.0!*;ÿ'--!/3!,ÿ+-ÿ'$;ÿ/*'+20ÿ"-ÿ'ÿ.!*!('$3ÿ)'3!$3ÿ'.!ÿ,!3!.2+$!,ÿ3"ÿ7!
`+$('*+,%ÿ1$'00!.3'7*!%ÿ".ÿ1$!$-"./!'7*!%ÿ".ÿ+-ÿ/"2)!3+$4ÿ).",1/30ÿ'.!ÿ+$3.",1/!,ÿ3&'3ÿ'.!ÿ3&!.')!13+/'**;ÿ0+2+*'.ÿ713ÿ3&'3ÿ,"ÿ$"3ÿ+$-.+$4!ÿ"1.
`).",1/309ÿ)'3!$305ÿ@-ÿ'$;ÿ01/&ÿ0+31'3+"$ÿ'--!/3!,ÿ"$!ÿ"-ÿ"1.ÿ7!0380!**+$4ÿ).",1/30%ÿ+3ÿ/"1*,ÿ&'(!ÿ'ÿ01703'$3+'*ÿ$!4'3+(!ÿ!--!/3ÿ"$ÿ"1.ÿ")!.'3+$4
`.!01*30%ÿ-+$'$/+'*ÿ)"0+3+"$ÿ'$,ÿ/'0&ÿ-*"#05ÿF'3!$3ÿ*+3+4'3+"$ÿ+0ÿ017:!/3ÿ3"ÿ01703'$3+'*ÿ1$/!.3'+$3;%ÿ'$,ÿ3&!.!ÿ+0ÿ$"ÿ'001.'$/!ÿ3&'3ÿ'$;ÿ"-ÿ3&!
`)'3!$30ÿ.!*'3+$4ÿ3"ÿ"1.ÿ).",1/30%ÿ+-ÿ/&'**!$4!,%ÿ#+**ÿ7!ÿ-"1$,ÿ('*+,ÿ'$,ÿ!$-"./!'7*!ÿ+$ÿ'$;ÿ".ÿ'**ÿ.!0)!/305ÿ@$ÿ',,+3+"$%ÿ#&!$ÿ#!ÿ01!ÿ3"
`!$-"./!ÿ"1.ÿ)'3!$30%ÿ3&!ÿ,!-!$,'$30ÿ2';ÿ'00!.3ÿ/"1$3!./*'+20ÿ1$,!.ÿ'$3+3.103ÿ".ÿ"3&!.ÿ*'#0%ÿ#&+/&ÿ/"1*,ÿ.!01*3ÿ+$ÿ:1,42!$30ÿ'4'+$03ÿ10ÿ-".
`,'2'4!0%
`G
`ÿ+$/*1,+$4ÿ3.!7*!ÿ,'2'4!0%ÿ3&'3ÿ/"1*,ÿ&'(!ÿ'ÿ2'3!.+'*ÿ',(!.0!ÿ!--!/3ÿ"$ÿ"1.ÿ")!.'3+$4ÿ.!01*30%ÿ-+$'$/+'*ÿ)"0+3+"$%ÿ'$,ÿ/'0&ÿ-*"#05
`ÿÿÿÿÿÿÿÿD&!ÿ!<3!$3ÿ"-ÿ)'3!$3ÿ)."3!/3+"$ÿ'*0"ÿ('.+!0ÿ-."2ÿ/"1$3.;ÿ3"ÿ/"1$3.;5ÿ@$ÿ0"2!ÿ/"1$3.+!0%ÿ)'3!$3ÿ)."3!/3+"$ÿ+0ÿ0+4$+-+/'$3*;ÿ#!'>!.ÿ3&'$
`+$ÿ3&!ÿA$+3!,ÿB3'3!0ÿ".ÿ3&!ÿH1.")!'$ÿA$+"$5ÿ@$ÿ)'.3+/1*'.%ÿ0"2!ÿ/"1$3.+!0ÿ2';ÿ-'/+*+3'3!ÿ/"2)!3+3+"$ÿ#+3&+$ÿ3&!+.ÿ2'.>!30ÿ7;ÿ.!C1+.+$4ÿ10ÿ3"
`4.'$3ÿ/"2)1*0".;ÿ*+/!$0!0ÿ3"ÿ"3&!.0ÿ3"ÿ2'$1-'/31.!ÿ".ÿ,+03.+713!ÿ4!$!.+/ÿ(!.0+"$0ÿ"-ÿ"1.ÿ)'3!$3!,ÿ).",1/30ÿ+$ÿ3&!+.ÿ/"1$3.+!0%ÿ7;ÿ)!.2+33+$4
`"3&!.0ÿ3"ÿ2'$1-'/31.!ÿ".ÿ,+03.+713!ÿ4!$!.+/ÿ(!.0+"$0ÿ"-ÿ"1.ÿ).",1/30ÿ+$ÿ(+"*'3+"$ÿ"-ÿ"1.ÿ)'3!$3ÿ.+4&30%ÿ".ÿ7;ÿ&'(+$4ÿ+$!--!/3+(!ÿ)'3!$3
`!$-"./!2!$3ÿ2!/&'$+0205
`ÿÿÿÿÿÿÿÿ@$ÿ3&!ÿA$+3!,ÿB3'3!0%ÿ3&!ÿ!--!/3+(!$!00ÿ"-ÿ)'3!$3ÿ)."3!/3+"$ÿ-".ÿ).!0/.+)3+"$ÿ,.140ÿI"3&!.ÿ3&'$ÿ7+"*"4+/'*0Jÿ+0ÿ0+4$+-+/'$3*;ÿ+$-*1!$/!,ÿ7;
`3&!ÿE'3/&8 '<2'$ÿK/3ÿ"-ÿLMNO%ÿ#&+/&ÿ)."(+,!0ÿ3&'3ÿ'ÿ$!#*;ÿ'))."(!,ÿ,.14ÿ".ÿ+$,+/'3+"$ÿ#+**ÿ.!/!+(!ÿ'ÿ03'313".;ÿ)!.+",ÿ"-ÿ2'.>!3+$4
`!</*10+(+3;ÿI-+(!ÿ;!'.0ÿ-".ÿ'ÿ$!#ÿ,.14ÿ'$,ÿ3&.!!ÿ;!'.0ÿ-".ÿ'ÿ$!#ÿ+$,+/'3+"$ÿ-".ÿ'$ÿ!<+03+$4ÿ,.14Jÿ,1.+$4ÿ#&+/&ÿ3&!ÿA5B5ÿ="",ÿ'$,ÿ6.14
`K,2+$+03.'3+"$ÿI=6KJÿ#+**ÿ$"3ÿ4.'$3ÿ2'.>!3+$4ÿ'))."('*ÿ3"ÿ4!$!.+/ÿ/"2)!3+3".0%ÿ!(!$ÿ+$ÿ3&!ÿ'70!$/!ÿ"-ÿ)'3!$3ÿ)."3!/3+"$ÿ"$ÿ3&!ÿ".+4+$'*
`).",1/35ÿD&!ÿ0'2!ÿK/3%ÿ&"#!(!.%ÿ&'0ÿ4.!'3*;ÿ'//!*!.'3!,ÿ3&!ÿ'))."('*ÿ)."/!00ÿ-".ÿ4!$!.+/ÿ/"2)!3+3".0ÿ10+$4ÿ3&!ÿ0'2!ÿ'/3+(!ÿ+$4.!,+!$30
`"$/!ÿ3&!ÿ03'313".;ÿ!</*10+(+3;ÿI'*0"ÿ.!-!..!,ÿ3"ÿ'0ÿ?,'3'ÿ!</*10+(+3;?Jÿ&'0ÿ!<)+.!,ÿ'$,ÿ2';ÿ'/31'**;ÿ!$/"1.'4!ÿ2".!ÿ'44.!00+(!ÿ*!4'*
`/&'**!$4!0ÿ3"ÿ3&!ÿ)'3!$3ÿ)."3!/3+"$ÿ"-ÿ7.'$,8$'2!ÿ).",1/305ÿ@$ÿ.!/!$3ÿ;!'.0%ÿ*!4+0*'3".0ÿ'$,ÿ+$3!.!03ÿ4."1)0ÿ&'(!ÿ2',!ÿ('.+"10ÿ).")"0'*0ÿ3"
`'2!$,ÿ3&!ÿE'3/&8 '<2'$ÿK/3ÿ3"ÿ'//!*!.'3!ÿ-1.3&!.ÿ3&!ÿ2'.>!3+$4ÿ"-ÿ4!$!.+/ÿ(!.0+"$0ÿ"-ÿ7.'$,8$'2!ÿ)&'.2'/!13+/'*ÿ).",1/30%ÿ+$/*1,+$4
`'$ÿ'2!$,2!$3ÿ',")3!,ÿ'0ÿ)'.3ÿ"-ÿ3&!ÿP!,+/'.!ÿF.!0/.+)3+"$ÿ6.14ÿ'$,ÿP",!.$+Q'3+"$ÿK/3ÿ"-ÿRSST5ÿK$;ÿ01/&ÿ