`
`100%
`
`80%
`
`60%
`
`40%
`
`20%
`
`0%--\-----..------.---------.--------.--------r-----==-==== -
`2010
`2011
`2005
`2006
`2007
`2008
`2009
`
`... - - ----;--- - -___,.I-____ ~=--- ----.1fi"'-- - -~1,--- - --
`2012
`2013
`2014
`2015
`2016
`2017
`2018
`
`...... Basaglar KwikPen Dollar Sales
`...... Lanius OptiClik Dollar Sales
`...... Lanius SoloSTAR Dollar Sales
`...... Levemir Pens Dollar Sales
`...... Toujeo Max SoloSTAR Dollar Sales
`...... Toujeo SoloSTAR Dollar Sales
`• •
`Tresiba FlexTouch Dollar Sales
`
`f'rtr-t', Basaglar KwikPen New Prescriptions
`f'rtr-t', Lanius OptiClik New Prescriptions
`f'rtr-t', Lanius SoloSTAR New Prescriptions
`f'rtr-t', Levemir Pens New Prescriptions
`f'rtr-t', Toujeo Max SoloSTAR New Prescriptions
`f'rtr-t', Toujeo SoloSTAR New Prescriptions
`Tresiba FlexTouch New Prescriptions
`
`+-+-+ Basaglar KwikPen Total Prescriptions
`+-+-+ Lanius OptiClik Total Prescriptions
`+-+-+ Lanius SoloSTAR Total Prescriptions
`+-+-+ Levemir Pens Total Prescriptions
`+-+-+ Toujeo Max SoloSTAR Total Prescriptions
`+-+-+ Toujeo SoloSTAR Total Prescriptions
`Tresiba FlexTouch Total Prescriptions
`
`Source: IMS Health
`Note: The long-acting category includes drugs listed under the IMS USC5 codes 39123 (Human Insulins Long Acting), 39133 (Analogs of Human Insulin Long Acting), and 39135
`(Analogs of Human Insulin Ultra Long Acting). Lantus OptiClik is defined as records with Product Summary "LANTUS" and Form TLC3 "FCC DISP SYR REGULAR SC.OL Y." Levemir
`Pens include Levemir FlexPen and Levemir FlexTouch. Products are designated as "Levemir FlexPen" if IMS Health data indicates that Product Summary is "LEVEMIR FLEXPEN" or if
`both Product Summary is "LEVEMIR" and TLC3 code is "GCC DISP SYR LG ACT SC ONLY." Toujeo Max SoloSTAR was first introduced in April 2018.
`
`Sanofi Exhibit 2199.001
`Mylan v. Sanofi
`IPR2018-01676
`
`