`
`Arthritis and Diabetes
`
`Arthritis
`Foundation
`
`ADVERTISEMENT
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`Available by prescrip!ion only
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`SCROLL FOR IMPORTANT SAFITT INFORMATION AND INDICATION
`
`IMPORTANT SAFETY INFORMATION
`
`XELJANZ/XELJANZ XR may cause serious side effects,
`including:
`
`Serious infections. XELJANZ/XELJANZ XR can lower the
`ability of your immune system to fight infections. Some people
`can have serious infections while taking XELJANZ/
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`FULL PRESCRIBING INFORMATION INCLUDING
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`-
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`Treatments
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`Health Care
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`Arthritis Diet
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`Exercise
`
`Coping with Change
`
`Comorbidities
`
`Depression
`
`Diabetes
`
`RA vs. OA & Diabetes
`
`Disease-Modifying Drugs May
`Lower Diabetes Risk
`
`Rheumatoid Arthritis Appears to
`Increase Diabetes Risk
`
`Heart Disease
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`Arthritis & Diabetes ~
`What do diabetes and arthritis
`have in common? Plenty.
`People with diagnosed diabetes are nearly twice as likely to have
`
`arthritis, indicating a diabetes-arthritis connection.
`
`Diabetes occurs when the body does not produce or use the
`
`hormone insulin sufficiently. Insulin shuttles glucose from foods
`
`into cells so it can be converted into energy. Without insulin,
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`glucose remains in your blood (raising blood glucose levels),
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`your cells create less energy and you feel fatigued.
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`What starts off as a hormonal problem can evolve into joint
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`problems, in addition to the widely known cardiovascular
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`Mouth Conditions
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`problems.
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`Kidney Disease
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`Diabetes causes musculoskeletal changes that lead to symptoms
`
`such as joint pain and stiffness; swelling; nodules under the skin,
`
`particularly in the fingers; tight, thickened skin; trigger finger;
`
`carpal tunnel syndrome; painful shoulders; and severely affected
`
`feet. After having had diabetes for several years, joint damage -
`
`called diabetic arthropathy - can occur.
`
`Related Resources:
`• RA vs. OA and Diabetes
`
`• Rheumatoid Arthritis Appears to Increase Diabetes
`Risk
`
`• Disease-Modifying Drugs May Lower Diabetes Risk
`
`• Metabolic Comorbidities of Psoriatic Arthritis
`
`Order Yours Free Today!
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`JUST DIAGNOSED?
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`manage your health in the FREE Better Living
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`https://www.arthritis.org/living-with-arthritis/comorbidities/diabetes-and-arthritis/
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`1/2
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`Sanofi Exhibit 2115.001
`Mylan v. Sanofi
`IPR2018-01675
`
`
`
`6/6/2019
`
`Arthritis and Diabetes
`
`XELJANZ'XR 1/J
`
`(tofacitinib]
`i:xti:nd!:d<d!:-,si: -11 mgtotJli: ts
`Available by prescription only
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`ASI< IF XELJANZ XR
`IS RIGHT FOR YOU.'
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`GETTO KNOW
`XELJANZ XR
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`tForpatientsinwhichmethotrexate
`orothersimilarmedicinesdidnot
`workwellenough.
`
`SCROLL FOR IMPORTANT SAFETY
`INFORMATION AND INDICATION
`
`IMPORTANT SAFETY
`INFORMATION AND
`INDICATION
`
`XELJANZ/XELJANZ XR may
`cause serious side effects,
`including:
`
`Serious infections .
`XELJANZ/XELJANZ XR can
`lower the ability of your
`immune system to fight
`infections. Some people can
`have serious infections while
`taking XELJANZ/
`XELJANZ XR, including
`1a
`I
`:
`....
`FULL PRESCRIBING INFORMATION
`INCLUDING BOXED WARNING
`AND MEDICATION GUIDE
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`About Arthritis
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`1355 Peachtree St NE
`Suite 600
`Atlanta,GA 30309
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`https://www.arthritis.org/living-with-arthritis/comorbidities/diabetes-and-arthritis/
`
`2/2
`
`Sanofi Exhibit 2115.002
`Mylan v. Sanofi
`IPR2018-01675
`
`