`
`80%
`
`60%
`
`40%
`
`20%
`
`0%L -~~ -~ -~ = - -~ -_f_-~__=:=~~~
`2010
`2001
`2002
`2003
`2004
`2005
`2006
`2007
`2008
`2009
`
`=====-==
`2011
`
`----
`2012
`
`-----
`2013
`
`....._-
`2014
`
`----------l,-----
`2015
`2016
`2017
`
`-
`
`2018
`
`._._. Lantus OptiClik Dollar Sales
`._._. Lantus SoloST AR Dollar Sales
`._._. Lantus Vial Dollar Sales
`
`tr--tri::i Lantus OptiClik New Prescriptions
`tr--tri::i Lantus SoloSTAR New Prescriptions
`tr--tri::i Lantus Vial New Prescriptions
`
`+-+-+ Lantus OptiClik Total Prescriptions
`+-+-+ Lantus SoloSTAR Total Prescriptions
`+-+-+ Lantus Vial Total Prescriptions
`
`Source: IMS Health
`Note: Lantus OptiClik is defined as records with Product Summary "LANTUS" and Form TLC3 "FCC DISP SYR REGULAR SC.OL Y." Lantus Vial is defined as records with Product
`Summary "LANTUS" and Form TLC3 "FDC VIAL REGULAR S.C. ONLY." Lantus SoloSTAR is defined as records with Product Summary "LANTUS SOLOSTAR."
`
`Sanofi Exhibit 2190.001
`Mylan v. Sanofi
`IPR2018-01675
`
`