Dr. Reddy’s Laboratories, Inc. v. Celgene Corp.
`IPR2018-01509
`Exhibit 2031, Page 1
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`

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`Dr. Reddy’s Laboratories, Inc. v. Celgene Corp.
`IPR2018-01509
`Exhibit 2031, Page 2
`
`

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`Dr. Reddy’s Laboratories, Inc. v. Celgene Corp.
`IPR2018-01509
`Exhibit 2031, Page 3
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`

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`Dr. Reddy’s Laboratories, Inc. v. Celgene Corp.
`IPR2018-01509
`Exhibit 2031, Page 4
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`

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`Dr. Reddy’s Laboratories, Inc. v. Celgene Corp.
`IPR2018-01509
`Exhibit 2031, Page 5
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`Dr. Reddy’s Laboratories, Inc. v. Celgene Corp.
`IPR2018-01509
`Exhibit 2031, Page 6
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`cytopathici
`cytotechn:
`
`diagnosis of cytomegalovirus (CMV)
`
`liver, kidney, lung, salivary glands, and other organs
`
`urine; inclusion bodies in epithelial cells,especially in
`children up to 3 mos.; saliva
`
`sé
`
`gentle negative pressure for the collection of vaginal
`for cytological examination.
`cy to-plasm(si‘t6-plazm). The substance of a cell. exc
`the nucleus. which contains various organelles and ir
`within a colloidal protoplasm. sth at so protoplasm. hya
`cytosol
`[eyto- + G. plasma. thing formed]
`ground-glass c.. uniform tinely granular eosinophilic ce.
`specific intranuclear and intracytoplasmic inclusions in
`
`fluorescence__tissue sections hepatocytes in carriers of hepatitis B virus. and alsoin e:
`cells in keratoacanthoma.
`cy-to-plas-mic (si-t6-plaz’mik). Relating to the cytoplass
`virus culture—_tissue cultures from urine, throat cultures,lymphocytes,
`cervical secretion, biopsy and necropsy materials
`cy to-plas-mon (si-té-plaz’mon), The total extranucleat
`(sperm, breast milk)
`information of a eukaryotic ceil excluding that of mito:
`and plastids.
`cy-to-plast (si’té-plast). The living intact cytoplasm that
`following cell enucleation. [cyto- + G. plastos. formed}
`cy to-poi-e-sis (si-t6-poy-esis). Formation ofcells. [cy
`poresis, a making}
`cy to-prep-a-ra‘tion (si’t0-prep-d-ra’shiin), Laboratory
`tion ofa cellular specimen for cytologic examination.
`cy to-py-ge (si-t6-pi'jé). The anal orifice (cell “anus”) |
`certain structurally complex protozoa, such as the rumen-1
`ciliates of herbivores,
`through which waste matter is
`[cyto- + G. pygé, buttocks}
`cy-to-ryc-tes, cy-tor-rhyc-tes (si-té-rik’téz). Obsolete
`inclusion bodies, under body. {cyto- + G. orykrés, a digge
`cytoscreener(si’t6-skrén’er). SYN os Cofectinibistiss
`cy-to-sides (si’t6-sidz). Ceramide disaccharides. sre gly:
`golipid.
`cy to-sine (Cyt) (si’td-sén). a pyrimidine found in nuclei
`c. arabinoside (CA, AraC), (1) a synthetic nucleoside us
`antimetabolite in the treatment of neoplasms: (2) incort:
`for arabinosyleytosine.
`c. ribonucleoside, syN os udine
`cy-to-sis (si-td’sis). 1. A condition in which there is more
`usual numberofcells, as in the c. of spinal fluid in acut
`meningitis. 2, Frequently used with a prefixed combining
`a means ofdescribing certain features pertaining to cel
`isocytosis, equality in size: polycytosis, abnormal
`ine
`number. [cyto- + G. -osis, condition]
`The tonofilaments,
`cy-to-skel-e-ton (si-t6-skel’é-ton).
`desmin, neurofilaments, or other intermediate filaments se
`act as supportive cytoplasmic elements to stiffen cells or
`nize intracellular organelles.
`cy to-smear (si’td-smér). SYN Cytolowie sees
`cy to-sol {si't6-sol). Cytoplasm exclusive of the mitocl
`endoplasmic reticulum, and other membranous comp
`[cyto- + “sol.” abbrev. of soluble]
`cy to-sol-ic (si-t6-sol’ik). Relating to or contained in the ¢
`cy to-some(si’té-sdm).
`1. The cell body exclusive of the 1
`2. Distinctive granule found in great alveolar (type ID) cell
`lung that releases pulmonary surfactant on the alveolar s
`SYN multilamellar body.
`[cyto- + G, sdma, body]
`cy tos-ta-sis (si-tos’ti-sis), The slowing of movement and
`ulation of blood cells, especially polymorphonuclear leul
`in the capillaries, as in a region of inflammation: obstruct
`capillary as the result of accumulated leukocytes.
`[cyte
`stasis. standing}
`cy to:stat-ic (si-t6-stavik). Characterized bycytostasis.
`cy to-stome (si’td-stom). The cell “mouth” of certain ¢
`protozoa, usually with a short guilet or cvtopharynx leadi
`into the organism, where it
`is collected into food vacuok
`circulated inside the body, eventually to be excreted thro
`cytopyge. [cyto- + G. stoma, mouth)
`cy-to-tac-tic (si-té-tak’tik). Relating to cytotaxis.
`cy to-tax-is, cy to: tax-ia (si-t6-tak’sis, -tak’s®-a), The at
`(positive c.) or repulsion (negative c.) of cells for one <
`{eyto- + G, taxis, arrangement]
`A person with
`cytotechnologist (sité-tek-nol’6-jis.
`training in cytopathology who is responsible for screeni
`smears and determining which are negative and which
`
`cy-top-a-thy (si-top’a-thé). Any disorder of a cell or anomaly of
`any ofits constituents. [cyto- + G. pathos, disease]
`SYN UTUISCS fOSES
`cy to-pemp:sis (si-té-pemp’sis).
`pempis, sending through}
`i.e., hypocytosis. or a
`cy to-pe-nia (si-t0-pé’né-a). A reduction,
`lack of cellular elements in the circulating blood.
`[eyto- + G.
`penia, poverty]
`cy toph-a-gy (si-tot’a-jé). Devouring of other cells by phago-
`evtes. [cyto- + G. phayéd, to devour]
`cy to-phan-ere(si‘t6-fa-nér). A radial spine Seen in certain cysts
`of Sarcocystis, as in rabbit and sheep tissue cysts. [cyto- + G.
`Phaneros, visible, evident, open|
`cy -to-phar-ynx (si’t6-far’inks). An organelle in certain flagellates
`and ciliates that serves as a gullet through which food material
`passes from the cytostome to the cell
`interior: food passed is
`vollected in food vacuoles.
`into which digestive enzymes are
`
`hybridization
`
`separation of cellular from viral DNA
`
`compiementbinding reaction (CBR), passive
`hemoagglutination, immunofiuorescence,neutralization
`test in tissue cultures,determination of igM antibodiesif
`active infection is suspected
`
`cy to-path-ie (si-t6-path’ik). Pertaining to or exhibiting cytopa-
`
`cy to path-o-gen-ie (si’té-path--jen‘ik). Pertaining to an agent
`or substance that causes a diseased condition in cells, in contrast
`to histologic changes; used especially with reference to effects
`observed in cells in tissue cultures.
`(si’t5-pa-th6-loj’ik,
`cy-to-path.o-log.ic, cy-to-path-o-log:i-cal
`-loy'i-kal), 1. Denoting cellular changes in disease. 2, Relating to
`eytopathology.
`A physician, usually
`cy-to-pa-thol.o-gist (si’t6-pa-thol’6-jist).
`skilled in anatomical pathology, who is specially trained and
`experienced in cytopathology.
`cy-to-pa-thol-o-gy (si‘td-pa-thol’6-j@).
`changes within individual cells or cell
`
`1. The study of disease
`types. 2. syn extolionve
`
`[eyto- + G.
`
`cy-to-phil-ic (si-to-fil’ik).
`
`SYN ostotrapie.
`
` [eyto- + G. philos.
`
`cy to: pho-tom-e-try (sité-f6-tom’é-tré). A method of measuring
`the absorption of monochromatic light by stained microscopic
`structures (é.g.. chromosomes, nuclei. whole cells) with the aid of
`4 photoelectric cell: also used to measure emitted light from such
`objects by fluorescence in combination with selected fluoro-
`chrome dyes. [eyto- + G. phds, light + merron, measure|
`flowc., SYN Tew ctor
`cy to-phy-lac-tic (sit0-fi-lak’k), Relating to evtophylaxis.
`cy to: phy -lax-is (si't6-tT-lak’sis). Protection of cells against Ivtic
`agents. [eyto- + G. phylaxis, a guarding }
`cy to-phy-let-ie (sité-ti-ler’ik).
`Relating to the genealogy of a
`cell. [cyto- + G. piylé, a tribe}
`cy to-pi-pette (sit6-pi-pet’).. A slightly curved. blunt end pipette
`usually made of glass and fitted with a rubber bulb to provide
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`Dr. Reddy’s Laboratories, Inc. v. Celgene Corp.
`IPR2018-01509
`Exhibit 2031, Page 8
`
`

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`Dr. Reddy’s Laboratories, Inc. v. Celgene Corp.
`IPR2018-01509
`Exhibit 2031, Page 9
`
`