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`Thomson Innovation Record View
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`Page 1of6
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`Patent Record Full View
`
`Thursday, July 25 2013
`
`Bibliography
`
`DWPI Title
`
`Method for correcting measuring parameters of radioisotope discontinuous threshold detector and device for
`
`realization of said method
`
`English Title
`
`METHOD FOR CORRECTING MEASURING PARAMETERS OF RADIOISOTOPE DISCONTINUOUS THRESHOLD
`
`DETECTOR AND DEVICE FOR REALIZATION OF SAID METHOD
`
`Assignee/ Applicant
`
`Standardized: OAO SOJUZTSVETMETAVTOMATIKA
`
`DWPI Assignee/ Applicant
`SOYUZTSVETMETAVTOMATIKA STOCK CO (SOYU-R)
`
`Inventor
`ULITENKO KONSTANTIN JAKOVLEVIC, KARJAKIN JURIJ LEONIDOVICH, DEMIN ALEKSANDR
`VIKTOROVICH,
`
`DWPI Inventor
`
`DEMIN AV; KARYAKIN YU L; ULITENKO K YA
`
`Publication Date (Kind Code)
`
`2007-09-27 (Cl)
`
`DWPI Accession/ Update
`2007-697597 I 200765
`
`Application Number / Date
`RU2006113988A I 2006-04-26
`
`Priority Number/ Date / Country
`RU2006113988A I 2006-04-26 I RU
`
`Abstract
`
`DWPI Abstract
`
`(RU2307378Cl)
`
`Novelty
`
`Suggested radioisotope discontinuous threshold detector contains a source of ionizing radiation, detector of
`
`ionizing radiation, threshold frequency generator, comparison device, to addition input of which detector is
`
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`connected, and to subtraction input - threshold frequency generator, and also interpolator, threshold
`
`cascade and executing mechanism, all serially connected to output of comparison device. Also, device
`
`additionally includes transformation time-setting device, launch input of which is connected to output of
`
`threshold cascade, and also electronic key, connected by input to detector of ionizing radiations, and by
`
`output - to control input of threshold frequency generator, control input of the key is connected to
`
`transformation time setting device. Described device realizes corresponding method for correcting
`
`measuring parameters of radioisotope discontinuous threshold detector.
`
`Use
`
`Nuclear physics, namely methods and devices for correcting and stabilizing measuring routes of
`
`radioisotope devices.
`
`Advantage
`
`Increased precision and increased stability of radioisotope discontinuous threshold detector.2 cl, 3 dwg
`
`Abstract
`
`FIELD: nuclear physics, namely methods and devices for correcting and stabilizing measuring routes of
`
`radioisotope devices. /\.SUBSTANCE: suggested radioisotope discontinuous threshold detector contains a
`
`source of ionizing radiation, detector of ionizing radiation, threshold frequency generator, comparison
`
`device, to addition input of which detector is connected, and to subtraction input - threshold frequency
`
`generator, and also interpolator, threshold cascade and executing mechanism, all serially connected to
`
`output of comparison device. Also, device additionally includes transformation time-setting device, launch
`
`input of which is connected to output of threshold cascade, and also electronic key, connected by input to
`
`detector of ionizing radiations, and by output - to control input of threshold frequency generator, control
`
`input of the key is connected to transformation time setting device. Described device realizes corresponding
`
`method for correcting measuring parameters of radioisotope discontinuous threshold detector. /\. EFFECT:
`
`increased precision and increased stability of radioisotope discontinuous threshold detector. /\. 2 cl, 3 dwg
`
`Classes/Indexing
`
`IPC
`
`DWPI Class
`
`S03
`
`DWPI Manual Codes
`
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`·""" Collapse DWPI Manual Codes
`
`EPI Manual Codes: S03-G02
`
`DWPI Chemistry Resource Numbers
`
`Collapse DWPI Chemistry Resource Numbers
`
`DWPI Registry Numbers
`
`Collapse DWPI Registry Numbers
`
`Plasdoc Punch Codes
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`Collapse Plasdoc Punch Codes
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`Plasdoc Key Serial Codes
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`Collapse Plasdoc Key Serial Codes
`
`Enhanced Polymer Indexing
`
`Collapse Enhanced Polymer Indexing
`
`Chemical Fragment Codes
`
`Collapse Chemical Fragment Codes
`
`Legal Status
`
`INPADOC Legal Status
`
`Get Family Legal Status
`
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`METHOD FOR
`CORRECTING
`MEASURING
`PARAMETERS OF
`RADIOISOTOPE
`OAO
`SOJUZTSVETMETAVTOMATIKA DISCONTINUOUS
`THRESHOLD DETECTOR
`AND DEVICE FOR
`REALIZATION OF SAID
`METHOD
`
`Family
`
`Family
`
`Collapse INPADOC Family (1)
`
`Collapse DWPI Family (1); Countries (1)
`
`Claims
`
`No Claims exist for this Record
`
`Description
`
`Background/ Summary
`
`Collapse Background/Summary
`
`Drawing Description
`
`Collapse Drawing Description
`
`Description
`
`Collapse Description
`
`Citations
`
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`Citation Record level
`
`Other
`
`DWPI Title Terms
`
`METHOD CORRECT MEASURE PARAMETER RADIOISOTOPE DISCONTINUE THRESHOLD DETECT DEVICE
`
`REALISE
`
`DWPI Related Accession Numbers
`
`Custom Fields
`
`1±1*17t~
`
`Internal Combustion Engine
`
`Renewable Energy
`
`Review Type
`
`Flag Status
`
`Tech Support
`
`First Tech Class
`
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`White Field
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`Unified APP name
`
`supplier CACC
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`Review Comments
`
`patent relevance v2
`
`NFC
`
`User Interface
`
`Mando
`
`IMPORTANCE
`
`automobile safe
`
`Copy1·i~Jht 200?-2(Jl3 THOMSON P.lUT~R.S
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`Electronic Acknowledgement Receipt
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`Title of Invention:
`
`INFUSION SYSTEMS INCLUDING COMPUTER-FACILITATED MAINTENANCE
`AND/OR OPERATION AND METHODS OF USE
`
`First Named Inventor/Applicant Name:
`
`Stephen E. Hidem
`
`Customer Number:
`
`22859
`
`Filer:
`
`Paul J. Lavanway Jr.
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`22859
`
`Customer Number
`
`PATENT
`Attorney Docket No.: 56782.1.7
`
`IN THE UNITED STATES PATENT AND TRADEMARK OFFICE
`
`First Named Inventor:
`
`Stephen E. Hidem
`
`Application No.:
`
`Filed:
`
`Title:
`
`12/137,364
`June 11, 2008
`
`Group Art Unit: 3763
`Examiner:
`ZHANG, Jenna
`
`INFUSION SYSTEMS INCLUDING COMPUTER-FACILITATED
`MAINTENANCE AND/OR OPERATION AND METHODS OF USE
`
`Mail Stop FINAL
`Commissioner for Patents
`P.O. Box 1450
`Alexandria, VA 22313-1450
`
`Dear Sir:
`
`AMENDMENT
`
`In response to the Final Office Action mailed May 28, 2013, the period of response for
`
`which runs through August 28, 2013, please amend the application as follows. This Amendment
`
`is accompanied by a Request for Continued Examination under 3 7 C.F.R. § 1.114 and constitutes
`
`a sufficient submission.
`
`Amendments to the Claims are reflected in the listing of claims which begins on page
`
`2 of this paper.
`
`Remarks begin on page 9 of this paper.
`
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`Application No. 12/137,364
`Response to Final Office Action date May 28, 2013
`
`AMENDMENTS TO THE CLAIMS
`
`This listing of claims will replace all prior versions and listings of claims in the application.
`
`Listing of Claims:
`
`1. (Currently Amended) A method for operating an infusion system, the system comprising an
`
`eluant reservoir, a pump coupled to the reservoir, an infusion tubing circuit, a radioisotope
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`generator, an activity detector, a waste bottle and a computer including a computer interface, the
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`infusion tubing circuit including an eluant line coupled to the pump and to the generator, a waste
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`line coupled to the generator and to the waste bottle, and a patient line coupled to the generator,
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`the method comprising:
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`entering, into the computer, via the computer interface, a command to activate the pump in
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`order to generate an eluate from a portion of a volume of eluant pumped through the
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`generator, via an elution within the generator;
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`receiving an indication that the elution is completed, from the computer, via the computer
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`interface, that the elution is completed, when the pump has completed pumping the
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`portion of the volume of eluant; and
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`receiving from the computer, via the computer interface, a display of time lapsed since the
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`elution was completed.
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`2. (Original) The method of claim 1, further comprising:
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`entering, into the computer, via a computer interface, the volume of eluant contained in the
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`reservoir, prior to the elution; and
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`receiving, from the computer interface, an indication of a volume of eluant in the reservoir,
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`based upon tracking the portion of the volume of eluant that is pumped from the
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`reservoir.
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`664 of 2568
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`

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`Application No. 12/137,364
`Response to Final Office Action date May 28, 2013
`
`3. (Previously Presented) The method of claim 1, further comprising:
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`coupling the patient line of the infusion tubing circuit to a first shielded test vial, in order to
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`collect a first sample of the eluate from the patient line during the elution;
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`measuring an activity of the first sample; and
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`entering into the computer, via the computer interface, the measured activity of the first
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`sample and a time between completion of the elution and the measuring of the activity,
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`the computer calculating a breakthrough of the generator.
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`4. (Original) The method of claim 3, further comprising:
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`selecting a breakthrough test procedure of the computer, via the computer interface, prior to
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`entering the command to activate the pump; and
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`wherein coupling the patient line to the first shielded test vial is instructed by the computer
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`interface, after selecting the breakthrough test.
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`5. (Previously Presented) The method of claim 3, further comprising:
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`exchanging the patient line of the infusion tubing circuit for a first new patient line, after
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`collecting the first sample;
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`coupling the first new patient line to a second shielded test vial;
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`repeating the steps of claim 1, after exchanging the patient line, wherein the pump is
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`activated a second time and a second elution takes place, in order to fill the second vial
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`with a second sample of the eluate from the first new patient line;
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`measuring an activity of the second sample; and
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`entering into the computer, via the computer interface, the measured activity of the second
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`sample and a time between completion of the second elution and the measuring of the
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`activity of the second sample, the computer calculating a calibration coefficient for the
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`infusion system based on the measured activity of the second sample and an activity of
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`the eluate detected, during the second elution, by the activity detector of the system.
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`665 of 2568
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`

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`Application No. 12/137,364
`Response to Final Office Action date May 28, 2013
`
`6. (Original) The method of claim 5, further comprising:
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`selecting a calibration procedure of the computer, via the computer interface, prior to
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`entering the command to activate the pump for the second time; and
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`wherein coupling the first new patient line to the second shielded test vial is instructed by the
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`computer interface, after selecting the calibration procedure.
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`7. (Original) The method of claim 5, further comprising:
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`exchanging the first new patient line of the infusion tubing circuit for a second new patient
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`line, after the computer calculates the calibration coefficient;
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`purging air from the second patient line;
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`coupling the second new patient line to a patient, after purging; and
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`repeating the steps of claim 1, after exchanging the first new patient line for the second new
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`patient line, wherein the pump is activated a third time and a third elution takes place, in
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`order to inject a dose of the eluate to the patient from the second patient line.
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`8. (Original) The method of claim 7, further comprising receiving a report from the computer,
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`upon completion of the third elution, the report including a patient identification number and at
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`least one quantification of the dose of the eluate.
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`9. (Previously Presented) The method of claim 1, further comprising:
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`coupling the patient line to a shielded test vial in order to collect a sample of the eluate from
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`the patient line during the elution;
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`measuring an activity of the sample; and
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`entering into the computer, via the computer interface, the measured activity of the sample
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`and a time between completion of the elution and measuring of the activity, the computer
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`calculating a calibration coefficient for the infusion system based on the measured
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`activity and an activity of the eluate detected, during elution, by the activity detector of
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`the system.
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`666 of 2568
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`

`

`Application No. 12/137,364
`Response to Final Office Action date May 28, 2013
`
`10. (Original) The method of claim 9, further comprising:
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`selecting a calibration procedure of the computer, via the computer interface, prior to
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`entering the command to activate the pump; and
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`wherein coupling the patient line to the shielded test vial is instructed by the computer
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`interface, after selecting the calibration procedure.
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`11. (Original) The method of claim 1, further comprising:
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`purging air from the patient line;
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`coupling the patient line to a patient, after purging, in order to inject a dose of the eluate to
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`the patient from the patient line; and
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`receiving a report from the computer, upon completion of the elution, the report including a
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`patient identification number and at least one quantification of the dose of the eluate.
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`12. (Original) The method of claim 1, wherein the computer interface comprises a touch(cid:173)
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`activated display screen.
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`13. (Original) The method of claim 1, further comprising:
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`receiving an indication, from the system, that the eluate is being diverted, from the generator,
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`through the waste line of the infusion tubing circuit, when the pump is activated;
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`receiving an indication, from the system, that the eluate is being diverted from the generator,
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`through the patient line of the infusion tubing circuit, when the pump is activated;
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`14. (Original) The method of claim 13, wherein:
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`the system further comprises a light projector;
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`the indication that the eluate is being diverted through the waste line comprises a flashing
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`light projection from the light projector; and
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`the indication that the eluate is being diverted through the patient line comprises a solid light
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`projection from the light projector.
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`15. (Original) The method of claim 13, further comprising receiving an indication from the
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`system that a peak bolus of radioactivity has been detected, in the eluate, by the activity detector.
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`667 of 2568
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`Application No. 12/137,364
`Response to Final Office Action date May 28, 2013
`
`16. (Original) The method of claim 15, wherein:
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`the system further comprises a light projector; and
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`the indication that the peak bolus of radioactivity has been detected comprises a flashing light
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`from the light projector.
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`17. (Original) The method of claim 1, further comprising:
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`entering, into the computer, via the computer interface, a command to set a waste bottle level
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`indicator to zero, when the waste bottle is empty and prior to entering the command to
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`activate the pump; and
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`receiving, from the computer, via the computer interface, an indication that the waste bottle
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`needs to be emptied, based upon the computer tracking a volume of the eluate that is
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`diverted, from the generator, through the waste line of the infusion tubing circuit.
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`18. (Withdrawn) A computer readable medium having computer executable instructions for
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`executing a method for maintaining an infusion system, the method comprising:
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`receiving, via a graphical user interface, a volume of eluant contained in a reservoir of the
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`infusion system prior to activating a pump of the infusion system to pump a portion of the
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`volume of eluant through a radioisotope generator of the system in order to generate, via
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`elution, an eluate;
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`tracking the portion of the volume of eluant that is pumped from the reservoir;
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`providing an indication of a volume of eluant within the reservoir; and
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`tracking a volume of the eluate that is diverted from the generator to the waste bottle;
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`providing an indication that the waste bottle needs to be emptied.
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`19. (Canceled)
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`20. (Withdrawn) A computer readable medium having computer executable instructions for
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`executing a method of calibrating an activity detector of an infusion system, the method
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`compnsmg:
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`receiving a calibration command;
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`668 of 2568
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`Application No. 12/137,364
`Response to Final Office Action date May 28, 2013
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`receiving calibration parameters relating to an elution process;
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`activating a pump of the infusion system to initiate the elution process, the elution process
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`producing a sample of an eluate;
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`tracking a time from the end of the elution process;
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`receiving from the activity detector of the infusion system an activity level detected during
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`the elution process;
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`receiving a measured activity level of the eluate sample obtained from a dose calibrator;
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`receiving a time measured from the completion of the elution process to the measurement of
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`the activity level by the dose calibrator;
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`calculating a calibration coefficient for the infusion system based on the measured activity
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`level of the eluate sample and activity level detected during the elution process; and
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`providing the calibration coefficient as an output.
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`21. (Withdrawn) A computer readable medium having computer executable instructions for
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`executing a method of conducting a breakthrough test of a radioisotope generator of an infusion
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`system, the method comprising:
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`receiving a breakthrough test command;
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`activating a pump of the infusion system to initiate an elution process, the elution process
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`using the generator to produce a sample of an eluate from a patient line;
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`tracking a time lapsed from the end of the elution process;
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`receiving a measured activity level of the eluate sample obtained from a dose calibrator;
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`receiving a time measured from the completion of the elution process to the measurement of
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`the activity level by the dose calibrator;
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`calculating a breakthrough of the radioisotope generator based on the measured activity level
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`and the time between completion of the elution process and the measuring of the activity
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`level; and
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`providing the breakthrough of the generator as an output.
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`669 of 2568
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`

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`Application No. 12/137,364
`Response to Final Office Action date May 28, 2013
`
`22. (Withdrawn) The computer readable medium of claim 21, further comprising:
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`receiving a second measured activity level of the eluate sample obtained from a dose
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`calibrator, the second measured activity level being a measurement taken at
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`predetermined time period after the completion of the elution process.
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`23. (Withdrawn) The computer readable medium of claim 21, wherein the predetermined time
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`period is 60 minutes after completion of the elution process.
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`24. (Withdrawn) A method for purging a tubing circuit of an infusion system with air, the
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`system comprising a pump coupled to the tubing circuit, a radioisotope generator, a waste bottle
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`and a computer including a computer interface, the method comprising:
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`receiving instructions from the computer, via the computer interface, to disconnect the pump
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`from an eluant reservoir of the system, and to by-pass the generator by disconnecting an
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`eluant line and an eluate line, of the tubing circuit, from the generator, and connecting the
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`eluant line to the eluate line; and
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`entering, into the computer, via the computer interface, a command to perform an air purge
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`of the tubing circuit, the air purge being automated, via the computer, to perform purges
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`of individual portions of the tubing circuit, in sequence, via control of the pump and of
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`two divergence valves of the tubing circuit;
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`wherein a first valve, of the two divergence valves, is located between a first portion of the
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`eluate line and two downstream portions of the eluate line, a fir