Measure
`Start
`End
`Period
`Sort
`
`MOLECULE_TICKER
`RX_00161 Comdty
`RX_00161 Comdty
`RX_00161 Comdty
`RX_02533 Comdty
`RX_02533 Comdty
`RX_02735 Comdty
`RX_02735 Comdty
`RX_02735 Comdty
`RX_02735 Comdty
`RX_02735 Comdty
`RX_02735 Comdty
`RX_02735 Comdty
`RX_02735 Comdty
`RX_03467 Comdty
`RX_03467 Comdty
`RX_03467 Comdty
`RX_03467 Comdty
`RX_03467 Comdty
`RX_03469 Comdty
`RX_03469 Comdty
`RX_03469 Comdty
`RX_03469 Comdty
`RX_03469 Comdty
`RX_03469 Comdty
`RX_03469 Comdty
`RX_03469 Comdty
`RX_03469 Comdty
`RX_03471 Comdty
`RX_03471 Comdty
`RX_03471 Comdty
`RX_03471 Comdty
`RX_03471 Comdty
`RX_03471 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`
`TOTAL_INTEGRATED_UNITS
`1/1/2009
`12/31/2018
`Per=Q
`Sort=A
`
`DRUG_NAME
`CAMPATH
`CAMPATH
`LEMTRADA
`GILENYA
`GILENYA
`COPAXONE
`COPAXONE
`COPAXONE
`COPAXONE
`GLATIRAMER ACETATE
`GLATIRAMER ACETATE
`GLATOPA
`GLATOPA
`AVONEX
`AVONEX
`AVONEX PEN
`AVONEX PEN
`AVONEX PEN
`AVONEX
`AVONEX ADMINISTRATION PACK
`AVONEX ADMINISTRATION PACK
`REBIF
`REBIF
`REBIF
`REBIF REBIDOSE
`REBIF REBIDOSE
`REBIF REBIDOSE
`BETASERON
`BETASERON
`BETASERON
`BETASERON
`EXTAVIA
`EXTAVIA
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`
`MOLECULE_NAME
`ALEMTUZUMAB
`ALEMTUZUMAB
`ALEMTUZUMAB
`FINGOLIMOD HCL
`FINGOLIMOD HCL
`GLATIRAMER ACETATE
`GLATIRAMER ACETATE
`GLATIRAMER ACETATE
`GLATIRAMER ACETATE
`GLATIRAMER ACETATE
`GLATIRAMER ACETATE
`GLATIRAMER ACETATE
`GLATIRAMER ACETATE
`INTERFERON BETA‐1A
`INTERFERON BETA‐1A
`INTERFERON BETA‐1A
`INTERFERON BETA‐1A
`INTERFERON BETA‐1A
`INTERFERON BETA‐1A/ALBUMIN
`INTERFERON BETA‐1A/ALBUMIN
`INTERFERON BETA‐1A/ALBUMIN
`INTERFERON BETA‐1A/ALBUMIN
`INTERFERON BETA‐1A/ALBUMIN
`INTERFERON BETA‐1A/ALBUMIN
`INTERFERON BETA‐1A/ALBUMIN
`INTERFERON BETA‐1A/ALBUMIN
`INTERFERON BETA‐1A/ALBUMIN
`INTERFERON BETA‐1B
`INTERFERON BETA‐1B
`INTERFERON BETA‐1B
`INTERFERON BETA‐1B
`INTERFERON BETA‐1B
`INTERFERON BETA‐1B
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`
`PRODUCT_INDICATOR
`B
`B
`B
`B
`B
`B
`B
`B
`B
`G
`G
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`G
`G
`G
`G
`G
`
`1
`
`DRUG_STRENGTH
`10MG/ML
`30MG/ML
`12MG/1.2ML
`0.5MG
`0.5MG
`20MG
`20MG
`20MG/ML
`40MG/ML
`20MG/ML
`40MG/ML
`20MG/ML
`40MG/ML
`30MCG/.5ML
`30MCG/.5ML
`30MCG/.5ML
`30MCG/.5ML
`30MCG/.5ML
`30MCG
`30MCG
`30MCG
`22MCG/.5ML
`44MCG/.5ML
`8.8‐22(6)
`22MCG/.5ML
`44MCG/.5ML
`8.8‐22(6)
`0.3MG
`0.3MG
`0.3MG
`0.3MG
`0.3MG
`0.3MG
`2MG/ML
`2MG/ML
`2MG/ML
`2MG/ML
`2MG/ML
`
`DRUG_PACKAGE_SIZE
`3.000
`1.000
`1.200
`28.000
`30.000
`1.000
`1.000
`1.000
`1.000
`1.000
`1.000
`1.000
`1.000
`0.500
`1.000
`0.500
`1.000
`1.000
`4.000
`1.000
`4.000
`0.500
`0.500
`4.200
`0.500
`0.500
`4.200
`1.000
`1.000
`15.000
`5.000
`1.000
`1.000
`10.000
`10.000
`10.000
`10.000
`10.000
`
`DRUG_FORM
`AMPULES INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`CAPSULE
`CAPSULE
`KITS INJECTABLE
`KITS INJECTABLE
`SYRINGES DISPOSABLE
`SYRINGES DISPOSABLE
`SYRINGES DISPOSABLE
`SYRINGES DISPOSABLE
`SYRINGES DISPOSABLE
`SYRINGES DISPOSABLE
`SYRINGES DISPOSABLE
`KITS INJECTABLE
`AUTO OR PEN INJECTOR
`PEN INJECTOR KIT
`PEN INJECTOR KIT
`KITS INJECTABLE
`KITS INJECTABLE
`KITS INJECTABLE
`SYRINGES DISPOSABLE
`SYRINGES DISPOSABLE
`SYRINGES DISPOSABLE
`AUTO OR PEN INJECTOR
`AUTO OR PEN INJECTOR
`AUTO OR PEN INJECTOR
`KITS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`KITS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`
`Biogen Exhibit 2108
`Mylan v. Biogen
`IPR 2018-01403
`
`Page 1 of 6
`
`
`Start
`End
`Period
`Sort
`
`MOLECULE_TICKER
`RX_00161 Comdty
`RX_00161 Comdty
`RX_00161 Comdty
`RX_02533 Comdty
`RX_02533 Comdty
`RX_02735 Comdty
`RX_02735 Comdty
`RX_02735 Comdty
`RX_02735 Comdty
`RX_02735 Comdty
`RX_02735 Comdty
`RX_02735 Comdty
`RX_02735 Comdty
`RX_03467 Comdty
`RX_03467 Comdty
`RX_03467 Comdty
`RX_03467 Comdty
`RX_03467 Comdty
`RX_03469 Comdty
`RX_03469 Comdty
`RX_03469 Comdty
`RX_03469 Comdty
`RX_03469 Comdty
`RX_03469 Comdty
`RX_03469 Comdty
`RX_03469 Comdty
`RX_03469 Comdty
`RX_03471 Comdty
`RX_03471 Comdty
`RX_03471 Comdty
`RX_03471 Comdty
`RX_03471 Comdty
`RX_03471 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`
`TOTAL_INTEGRATED_UNITS
`1/1/2009
`12/31/2018
`Per=Q
`Sort=A
`
`DRUG_NAME
`CAMPATH
`CAMPATH
`LEMTRADA
`GILENYA
`GILENYA
`COPAXONE
`COPAXONE
`COPAXONE
`COPAXONE
`GLATIRAMER ACETATE
`GLATIRAMER ACETATE
`GLATOPA
`GLATOPA
`AVONEX
`AVONEX
`AVONEX PEN
`AVONEX PEN
`AVONEX PEN
`AVONEX
`AVONEX ADMINISTRATION PACK
`AVONEX ADMINISTRATION PACK
`REBIF
`REBIF
`REBIF
`REBIF REBIDOSE
`REBIF REBIDOSE
`REBIF REBIDOSE
`BETASERON
`BETASERON
`BETASERON
`BETASERON
`EXTAVIA
`EXTAVIA
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`
`MOLECULE_NAME
`ALEMTUZUMAB
`ALEMTUZUMAB
`ALEMTUZUMAB
`FINGOLIMOD HCL
`FINGOLIMOD HCL
`GLATIRAMER ACETATE
`GLATIRAMER ACETATE
`GLATIRAMER ACETATE
`GLATIRAMER ACETATE
`GLATIRAMER ACETATE
`GLATIRAMER ACETATE
`GLATIRAMER ACETATE
`GLATIRAMER ACETATE
`INTERFERON BETA‐1A
`INTERFERON BETA‐1A
`INTERFERON BETA‐1A
`INTERFERON BETA‐1A
`INTERFERON BETA‐1A
`INTERFERON BETA‐1A/ALBUMIN
`INTERFERON BETA‐1A/ALBUMIN
`INTERFERON BETA‐1A/ALBUMIN
`INTERFERON BETA‐1A/ALBUMIN
`INTERFERON BETA‐1A/ALBUMIN
`INTERFERON BETA‐1A/ALBUMIN
`INTERFERON BETA‐1A/ALBUMIN
`INTERFERON BETA‐1A/ALBUMIN
`INTERFERON BETA‐1A/ALBUMIN
`INTERFERON BETA‐1B
`INTERFERON BETA‐1B
`INTERFERON BETA‐1B
`INTERFERON BETA‐1B
`INTERFERON BETA‐1B
`INTERFERON BETA‐1B
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`
`PRODUCT_INDICATOR
`B
`B
`B
`B
`B
`B
`B
`B
`B
`G
`G
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`G
`G
`G
`G
`G
`
`1
`
`DRUG_STRENGTH
`10MG/ML
`30MG/ML
`12MG/1.2ML
`0.5MG
`0.5MG
`20MG
`20MG
`20MG/ML
`40MG/ML
`20MG/ML
`40MG/ML
`20MG/ML
`40MG/ML
`30MCG/.5ML
`30MCG/.5ML
`30MCG/.5ML
`30MCG/.5ML
`30MCG/.5ML
`30MCG
`30MCG
`30MCG
`22MCG/.5ML
`44MCG/.5ML
`8.8‐22(6)
`22MCG/.5ML
`44MCG/.5ML
`8.8‐22(6)
`0.3MG
`0.3MG
`0.3MG
`0.3MG
`0.3MG
`0.3MG
`2MG/ML
`2MG/ML
`2MG/ML
`2MG/ML
`2MG/ML
`
`DRUG_PACKAGE_SIZE
`3.000
`1.000
`1.200
`28.000
`30.000
`1.000
`1.000
`1.000
`1.000
`1.000
`1.000
`1.000
`1.000
`0.500
`1.000
`0.500
`1.000
`1.000
`4.000
`1.000
`4.000
`0.500
`0.500
`4.200
`0.500
`0.500
`4.200
`1.000
`1.000
`15.000
`5.000
`1.000
`1.000
`10.000
`10.000
`10.000
`10.000
`10.000
`
`DRUG_FORM
`AMPULES INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`CAPSULE
`CAPSULE
`KITS INJECTABLE
`KITS INJECTABLE
`SYRINGES DISPOSABLE
`SYRINGES DISPOSABLE
`SYRINGES DISPOSABLE
`SYRINGES DISPOSABLE
`SYRINGES DISPOSABLE
`SYRINGES DISPOSABLE
`SYRINGES DISPOSABLE
`KITS INJECTABLE
`AUTO OR PEN INJECTOR
`PEN INJECTOR KIT
`PEN INJECTOR KIT
`KITS INJECTABLE
`KITS INJECTABLE
`KITS INJECTABLE
`SYRINGES DISPOSABLE
`SYRINGES DISPOSABLE
`SYRINGES DISPOSABLE
`AUTO OR PEN INJECTOR
`AUTO OR PEN INJECTOR
`AUTO OR PEN INJECTOR
`KITS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`KITS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`
`Biogen Exhibit 2108
`Mylan v. Biogen
`IPR 2018-01403
`
`Page 1 of 6
`
`
`
`Q1
`
`Q2
`
`Q3
`
`Q4
`
`Q1
`
`Q2
`
`Q3
`
`Q4
`
`Q1
`
`2011
`2010
`2010
`2010
`2010
`2009
`2009
`2009
`2009
`Q1_2009 Q2_2009 Q3_2009 Q4_2009 Q1_2010 Q2_2010 Q3_2010 Q4_2010 Q1_2011
`
`Q2
`
`Q3
`
`Q4
`
`Q1
`
`Q2
`
`Q3
`
`Q4
`
`Q1
`
`Q2
`
`Q3
`
`2013
`2013
`2013
`2012
`2012
`2012
`2012
`2011
`2011
`2011
`Q2_2011 Q3_2011 Q4_2011 Q1_2012 Q2_2012 Q3_2012 Q4_2012 Q1_2013 Q2_2013 Q3_2013
`
`8390
`
`8058
`
`7613
`
`7261
`
`7030
`
`8208
`
`7410
`
`6913
`
`7166
`
`7221
`
`8113
`
`8127
`
`7999
`
`8239
`
`7624
`
`36
`
`90
`
`69
`
`‐3
`
`111687
`690
`4622262
`
`102332
`360
`5688849
`
`64173
`90
`5912624
`
`3752
`
`1593
`60
`5773916 5122710
`
`930
`30
`5492481
`
`112
`
`480
`
`63408
`
`367004
`
`781731 1413428 1928411 1487686
`
`1473747
`
`1522314
`
`1438083 1439096
`
`1564676
`
`1618689
`
`240
`
`90
`
`30
`
`182
`240
`31
`60
`4989059 5338964 6070899 6613594 6864650
`
`90
`
`30
`
`60
`
`120
`
`60
`
`60
`
`7222722
`
`7227474
`
`6442266 6041368
`
`5917649
`
`5528413
`
`4911619
`
`4936672
`
`354
`820695
`
`420
`960959
`
`710
`977119
`
`584
`963158
`
`567
`828889
`
`499
`853983
`
`502
`748926
`
`378
`758865
`
`273
`736224
`
`8972
`8294
`246
`777794 1133454 1298767
`
`8091
`639415
`
`3234
`650171
`
`3864
`558779
`
`150534
`
`MANUFACTURER_NAME
`BERLEX
`GENZYME
`GENZYME
`NOVARTIS
`NOVARTIS
`AVENTIS PHARMA
`REPACKER
`TEVA NEUROSCIEN
`TEVA NEUROSCIEN
`MYLAN
`MYLAN
`SANDOZ INC
`SANDOZ INC
`BIOGEN‐IDEC
`BIOGEN‐IDEC
`BIOGEN‐IDEC
`BIOGEN PHARMA
`BIOGEN‐IDEC
`REPACKER
`BIOGEN‐IDEC
`BIOGEN‐IDEC
`EMD SERONO INC
`EMD SERONO INC
`EMD SERONO INC
`EMD SERONO INC
`EMD SERONO INC
`EMD SERONO INC
`BAYER PHARM DIV
`BERLEX
`BERLEX
`BERLEX
`NOVARTIS
`NOVARTIS
`APP PHARMA
`BEDFORD LABS
`NOVAPLUS/SICOR
`OTN (JV LP)
`PFIZER/HOSPIRA
`
`3145
`427791
`2278
`194484
`
`2939
`349391
`2746
`218204
`
`1864
`316033
`2693
`247926
`
`1844
`281026
`2492
`241186
`
`39819
`
`62
`71034
`49272
`932008
`35073.8
`
`56
`80128
`59235
`1111903
`41089.2
`
`49
`80270
`61329
`1144206
`38644.2
`
`52
`76040
`61441
`1114701
`34543
`
`120
`67299
`53351
`968051
`32765.6
`
`118
`67706
`61077
`1016787
`35349.6
`
`132
`61009
`57423
`921476
`27866.6
`
`76
`60741
`59613
`935600
`25124
`
`88
`58191
`59634
`912988
`26278.4
`
`512
`606
`809
`76
`47966
`96294
`85143
`61107
`74975
`78438
`72903
`64424
`951780 1025379 1081680 1053144
`28198.4
`26630.4
`26940.6
`28098.4
`
`178
`48029
`78458
`1066404
`28496.4
`
`212
`43601
`79156
`1059235
`24091.8
`
`244
`40163
`73263
`963073
`20028.8
`
`1269419
`212
`
`1393427
`367
`
`1410074
`205
`
`1380358 1181023
`159
`16
`
`1204480
`30
`
`1065471
`14
`
`1048822
`5
`
`1150612 1175758 1163894 1061515
`
`916796
`73
`
`924700
`28
`
`891937
`43
`
`744012
`14
`
`217
`34850
`66184
`881121
`19585.2
`264
`1594
`721.4
`653504
`
`66
`32903
`57754
`801589
`8235.6
`4666
`40615
`10185.4
`607938
`14
`
`136
`29894
`51347
`714102
`6254.6
`8218
`81251
`11327.2
`517589
`
`4988
`
`10677
`
`15263
`
`20506
`
`22508
`
`23296
`
`24942
`
`32603
`
`33259
`
`33500
`
`36334
`
`35853
`
`34344
`
`30508
`
`19410
`180
`80
`8480
`12810
`
`10890
`50
`
`4680
`18850
`
`12382
`90
`
`‐250
`21770
`
`16748
`260
`
`50
`20710
`
`16462
`250
`
`40
`15500
`
`19260
`110
`
`80
`22370
`
`24570
`70
`
`70
`33730
`
`18290
`70
`
`20
`23630
`
`22752
`130
`
`50
`36539
`
`2
`
`20760
`100
`
`19810
`30
`
`17430
`30
`
`17480
`20
`
`12890
`
`14900
`
`11430
`
`12170
`
`27477
`45
`10410
`
`26241
`60
`12150
`
`22840
`
`22551
`
`22830
`
`20480
`
`16185
`
`18330
`
`16940
`
`17610
`
`16890
`
`16970
`
`Page 2 of 6
`
`
`
`Q4
`
`Q1
`
`Q2
`
`Q3
`
`Q4
`
`Q1
`
`Q2
`
`Q3
`
`Q4
`
`Q1
`
`Q2
`
`Q3
`
`Q4
`
`2018
`2017
`2017
`2017
`2017
`2016
`2016
`2016
`2016
`2015
`2015
`2015
`2015
`2014
`2014
`2014
`2014
`2013
`Q4_2013 Q1_2014 Q2_2014 Q3_2014 Q4_2014 Q1_2015 Q2_2015 Q3_2015 Q4_2015 Q1_2016 Q2_2016 Q3_2016 Q4_2016 Q1_2017 Q2_2017 Q3_2017 Q4_2017 Q1_2018
`
`Q1
`
`Q2
`
`Q3
`
`Q4
`
`Q1
`
`Q2
`
`2018
`Q2_2018
`
`Q3
`
`2018
`Q3_2018
`
`Q4
`
`2018
`Q4_2018
`
`‐21
`
`‐4
`
`1652667 1536687
`
`1680324
`
`1765812
`
`60
`
`120
`
`326
`1840411 1905822
`8924
`
`30
`
`1198
`1008687
`1030008
`
`1304
`26135
`2107523
`
`946
`1028
`5672
`8654
`2095975 2138017
`
`1011
`4833
`2269377
`60
`
`1371.8
`3371
`2266244
`120
`
`692
`901.6
`1038
`1788
`2264076 2215265
`
`898.6
`564
`2258735
`
`935
`123
`2210200
`30
`
`961.4
`112
`2175137
`
`808.2
`146
`2186892
`30
`
`904
`58
`2198125
`
`902.8
`30
`2179831
`
`751.6
`21
`2143533
`
`5029007 4231245
`199928
`
`3097929
`894952
`
`2458686
`1236235
`
`2194662 1861217
`1401446 1497438
`
`1793352
`1659320
`
`1369526
`1776045
`
`1218051 1012489
`1815735 1850567
`
`928786
`2005014
`
`893798
`2045459
`
`741824
`847448
`2042286 1924755
`
`722780
`1967999
`
`703422
`2007056
`
`7874
`
`292666
`
`311387
`
`346103
`
`368228
`
`383226
`
`364715
`
`330970
`
`323915
`
`323515
`
`1522
`247740
`2364
`235204
`
`3085
`206754
`4013
`220717
`
`1791
`198998
`2851
`244544
`
`1315
`184501
`2088
`242416
`
`1248
`173558
`1945
`232420
`
`146583
`
`193155
`
`4
`148064
`
`141028
`
`12
`146748
`
`232
`192558
`
`12
`142523
`
`297
`189179
`
`6
`142254
`
`237
`189754
`
`554044
`1556583
`41323
`321784.58
`272373
`4564
`239
`97699
`706
`
`129977
`
`472763
`1293721
`107368
`355499.96
`222754
`41497
`171
`90441
`603
`
`121389
`
`147646
`2
`91113
`95829
`
`2
`16745
`32608
`460871
`3357.8
`13289
`173752
`6133
`403043
`
`4037
`185704
`
`1280
`182945
`
`16214
`32556
`436837
`3325.8
`13802
`181038
`7733
`406259
`
`15448
`30354
`418906
`2747.4
`15079
`181959
`6216.4
`392167
`
`5
`144613
`6
`511
`179805
`
`15811
`30094
`401456
`4383.4
`14634
`180921
`8736.4
`372915
`
`15948
`28985
`407785
`3782.6
`15125
`186342
`7667
`383731
`
`52498
`
`51679
`
`50419
`
`51749
`
`48800
`
`10470
`
`11810
`
`16020
`
`12663
`
`15735
`
`8
`17548
`34719
`474285
`3201.6
`14213
`172467
`6918.6
`406024
`
`51856
`30
`12180
`
`1
`14849
`27946
`391222
`3398
`15282
`192607
`7332.6
`365750
`21
`
`46095
`4
`20341
`
`123
`25428
`42061
`597530
`4340.4
`11021
`108325
`9391.2
`496206
`
`220
`22285
`42140
`596246
`5683.6
`11876
`137711
`8781.6
`398154
`
`213
`22653
`41542
`580021
`3966.6
`13066
`157333
`8501.6
`446339
`
`129
`21301
`39268
`548448
`3632
`14057
`174137
`8475
`429714
`
`50
`20623
`37935
`518999
`3888.8
`15012
`176003
`6775.8
`399837
`
`27706
`
`48719
`
`58256
`
`58875
`
`53142
`
`10580
`
`10450
`
`8900
`
`8410
`
`11080
`
`563147
`635492
`1580199
`1745665
`35818
`17640
`161165 280027.67
`300411
`282511
`72
`368
`98990
`918
`29
`132597
`
`212
`103222
`714
`56
`137723
`
`518845
`1403516
`79703
`334693.62
`241861
`35632
`198
`93140
`688
`28
`124686
`
`11592
`26719
`345514
`2387.6
`17161
`193988
`5362.8
`325546
`
`10935
`25507
`331670
`2496.6
`17037
`187797
`6210.2
`311271
`
`11056
`24417
`320197
`2344.8
`16551
`189222
`5842.2
`301094
`
`9834
`23956
`319749
`2276.8
`16942
`190493
`5226.8
`275947
`
`6235
`22818
`302359
`1500.6
`15798
`181584
`4368.4
`244261
`
`150
`113955
`287
`148
`151717
`
`12157
`25418
`368162
`3224
`16174
`200940
`7436.4
`330438
`
`520
`111966
`1383
`68
`149496
`
`11701
`27711
`363340
`2836.8
`17699
`199514
`6563.2
`338117
`
`296
`108742
`1121
`4
`144688
`
`11445
`26432
`359775
`2626.6
`17317
`194708
`6228.8
`321642
`
`14692
`28656
`404223
`3129.6
`16821
`209224
`7103
`352903
`
`44878
`
`39056
`
`37183
`
`33300
`
`24710
`
`13130
`
`21110
`
`21700
`
`33041
`15
`12911
`
`29778
`60
`4610
`
`27518
`60
`14842
`
`25461
`45
`19146
`
`23758
`75
`19698
`
`12440
`
`12850
`
`12250
`
`12470
`
`13280
`
`9640
`
`10360
`
`6364
`
`‐190
`
`‐350
`
`‐70
`
`‐10
`
`10
`
`20
`
`240
`
`9030
`
`12700
`
`1510
`
`576
`
`90
`
`3
`
`Page 3 of 6
`
`
`
`Measure
`Start
`End
`Period
`Sort
`
`MOLECULE_TICKER
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04325 Comdty
`RX_04585 Comdty
`RX_04585 Comdty
`RX_23190 Comdty
`RX_23190 Comdty
`RX_24384 Comdty
`RX_24384 Comdty
`RX_24384 Comdty
`RX_24384 Comdty
`RX_28506 Comdty
`RX_28506 Comdty
`RX_28506 Comdty
`RX_28506 Comdty
`RX_33868 Comdty
`
`TOTAL_INTEGRATED_UNITS
`1/1/2009
`12/31/2018
`Per=Q
`Sort=A
`
`DRUG_NAME
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`NOVANTRONE
`NOVANTRONE
`NOVANTRONE
`NOVANTRONE
`NOVANTRONE
`NOVANTRONE
`NOVANTRONE
`NOVANTRONE
`NOVANTRONE
`TYSABRI
`TYSABRI
`AUBAGIO
`AUBAGIO
`DIMETHYL FUMARATE
`TECFIDERA
`TECFIDERA
`TECFIDERA
`PLEGRIDY
`PLEGRIDY
`PLEGRIDY PEN
`PLEGRIDY PEN
`OCREVUS
`
`MOLECULE_NAME
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`MITOXANTRONE HCL
`NATALIZUMAB
`NATALIZUMAB
`TERIFLUNOMIDE
`TERIFLUNOMIDE
`DIMETHYL FUMARATE
`DIMETHYL FUMARATE
`DIMETHYL FUMARATE
`DIMETHYL FUMARATE
`PEGINTERFERON BETA‐1A
`PEGINTERFERON BETA‐1A
`PEGINTERFERON BETA‐1A
`PEGINTERFERON BETA‐1A
`OCRELIZUMAB
`
`DRUG_STRENGTH
`2MG/ML
`2MG/ML
`2MG/ML
`2MG/ML
`2MG/ML
`2MG/ML
`2MG/ML
`2MG/ML
`2MG/ML
`2MG/ML
`2MG/ML
`2MG/ML
`2MG/ML
`2MG
`2MG
`2MG
`2MG
`2MG
`2MG
`2MG/ML
`2MG/ML
`2MG/ML
`300MG/15ML
`300MG/15ML
`14MG
`7MG
`
`120‐240MG
`120MG
`240MG
`125MCG/0.5
`63‐94MCG
`125MCG/0.5
`63‐94MCG
`300MG/10ML
`
`DRUG_PACKAGE_SIZE
`10.000
`12.500
`12.500
`12.500
`12.500
`12.500
`12.500
`15.000
`15.000
`15.000
`15.000
`15.000
`15.000
`10.000
`10.000
`12.500
`12.500
`15.000
`15.000
`10.000
`12.500
`15.000
`15.000
`15.000
`28.000
`28.000
`1.000
`60.000
`14.000
`60.000
`0.500
`1.000
`0.500
`1.000
`10.000
`
`DRUG_FORM
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`VIALS INJECTABLE
`TABLET
`TABLET
`BULK MISCELLANEOUS
`DELAYED RELEASE CAPSULE (ENTER
`DELAYED RELEASE CAPSULE (ENTER
`DELAYED RELEASE CAPSULE (ENTER
`SYRINGES DISPOSABLE
`SYRINGES DISPOSABLE
`AUTO OR PEN INJECTOR
`AUTO OR PEN INJECTOR
`VIALS INJECTABLE
`
`PRODUCT_INDICATOR
`G
`G
`G
`G
`G
`G
`G
`G
`G
`G
`G
`G
`G
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`B
`N
`B
`B
`B
`B
`B
`B
`B
`B
`
`4
`
`Page 4 of 6
`
`
`
`MANUFACTURER_NAME
`TEVA PARENTERAL
`APP PHARMA
`BEDFORD LABS
`NOVAPLUS/SICOR
`OTN (JV LP)
`PFIZER/HOSPIRA
`TEVA PARENTERAL
`APP PHARMA
`BEDFORD LABS
`NOVAPLUS/SICOR
`OTN (JV LP)
`PFIZER/HOSPIRA
`TEVA PARENTERAL
`IMMUNEX
`SERONO LABS
`IMMUNEX
`SERONO LABS
`IMMUNEX
`SERONO LABS
`EMD SERONO INC
`EMD SERONO INC
`EMD SERONO INC
`BIOGEN‐IDEC
`ELAN PHARMA
`AVENTIS PHARMA
`AVENTIS PHARMA
`PROFESSIONAL CO
`BIOGEN‐IDEC
`BIOGEN‐IDEC
`BIOGEN‐IDEC
`BIOGEN‐IDEC
`BIOGEN‐IDEC
`BIOGEN‐IDEC
`BIOGEN‐IDEC
`GENENTECH INC
`
`Q4
`
`Q1
`
`Q2
`
`Q3
`
`Q4
`
`Q1
`
`Q1
`
`Q2
`
`Q3
`
`2011
`2010
`2010
`2010
`2010
`2009
`2009
`2009
`2009
`Q1_2009 Q2_2009 Q3_2009 Q4_2009 Q1_2010 Q2_2010 Q3_2010 Q4_2010 Q1_2011
`29460
`33512
`37544
`30400
`26880
`23921
`2270
`1620
`7800
`10170
`9843.5
`8618
`8313
`7063.5
`9462.5
`9600
`6888.5
`5026
`4005
`62.5
`‐37.5
`‐25
`‐25
`
`Q2
`
`Q3
`
`Q4
`
`Q1
`
`Q2
`
`Q3
`
`Q4
`
`Q1
`
`Q2
`
`Q3
`
`2013
`2013
`2013
`2012
`2012
`2012
`2012
`2011
`2011
`2011
`Q2_2011 Q3_2011 Q4_2011 Q1_2012 Q2_2012 Q3_2012 Q4_2012 Q1_2013 Q2_2013 Q3_2013
`4771
`1680
`60
`1540
`7970
`2130
`6370
`7410
`8690
`5450
`6901
`6462.5
`5312.5
`5300
`2552.5
`5225
`4112.5
`2925
`3100.5
`2287.5
`26
`13
`
`1950
`2787.5
`14465
`3045
`5180
`
`‐75
`1125
`2640
`
`1100
`5937.5
`14217.5
`3390
`180
`
`‐275
`7513.5
`13157
`3135
`
`8486.5
`11467.5
`3525
`‐60
`
`8065
`11542
`2370
`
`4051
`9821
`3330
`
`11288.5
`1416
`2820
`
`13039.5
`776
`2865
`
`9442
`5213.5
`1740
`
`8255
`2938
`1770
`
`8577
`1138.5
`1260
`
`7402.5
`‐75
`1725
`
`9239
`662.5
`675
`
`12787.5
`2975
`2040
`
`6225
`1775
`1215
`
`8562.5
`2637.5
`690
`
`8038.5
`2312.5
`270
`
`4750
`3000.5
`135
`
`7565
`1425
`990
`
`1665
`4335
`
`1770
`3750
`
`2025
`3315
`
`2115
`2790
`
`375
`2295
`
`525
`300
`
`1275
`240
`
`795
`2100
`
`915
`300
`
`1110
`60
`
`690
`‐255
`
`2580
`270
`
`3810
`660
`
`1455
`570
`
`1020
`765
`
`1320
`1005
`
`840
`1215
`
`825
`375
`
`3618
`
`2970
`
`2820
`
`1890
`
`1681
`
`1020
`
`1092
`
`771
`
`902
`
`350
`
`1
`
`543735
`
`590306
`
`635550
`
`663360
`
`604359
`
`631740
`
`617162
`
`635415
`
`616275
`
`657058 1003140 1160925
`
`825945
`
`876736
`
`886726
`
`899923
`45635
`9956
`
`923566
`175888
`33464
`
`870254
`309164
`48092
`
`910203
`43857
`978921
`
`121830
`676727
`369684
`49758
`
`770537
`95856
`3158208
`
`5
`
`Page 5 of 6
`
`
`
`Q4
`
`Q1
`
`Q2
`
`Q3
`
`Q4
`
`Q1
`
`Q2
`
`Q3
`
`Q4
`
`Q1
`
`Q2
`
`Q3
`
`Q4
`
`Q1
`
`Q2
`
`Q3
`
`Q4
`
`Q1
`
`Q2
`
`2018
`Q2_2018
`
`Q3
`
`2018
`Q3_2018
`
`Q4
`
`2018
`Q4_2018
`
`4712.5
`
`3300
`
`2138.5
`
`2018
`2017
`2017
`2017
`2017
`2016
`2016
`2016
`2016
`2015
`2015
`2015
`2015
`2014
`2014
`2014
`2014
`2013
`Q4_2013 Q1_2014 Q2_2014 Q3_2014 Q4_2014 Q1_2015 Q2_2015 Q3_2015 Q4_2015 Q1_2016 Q2_2016 Q3_2016 Q4_2016 Q1_2017 Q2_2017 Q3_2017 Q4_2017 Q1_2018
`9580
`10540
`10442
`13190
`14680
`13450
`12560
`21736
`20683
`23002
`22610
`13230
`‐760
`‐110
`1287.5
`225
`87.5
`13
`987.5
`762.5
`1025
`1212.5
`1950
`1512.5
`1500
`3601
`4151
`10263.5
`
`4950
`3212.5
`480
`
`5550.5
`3950.5
`615
`
`5845
`2950
`660
`
`5351.5
`4462.5
`540
`
`6201
`3750
`525
`
`4514
`3550
`990
`
`4512.5
`4850
`210
`
`1874.5
`5062.5
`1575
`
`‐287.5
`7263
`1770
`
`‐100
`5000
`1140
`
`4380
`1005
`
`6176.5
`1410
`
`12165
`1907
`
`17789
`2434
`
`9926.5
`810
`
`5938.5
`1260
`
`7151.5
`1516
`
`1813
`8976.5
`1500
`
`925
`6789.5
`1350
`
`2437.5
`6062.5
`1215
`
`1138
`5851
`1185
`
`2010
`
`1530
`
`3750
`
`1890
`
`1635
`
`2835
`
`2925
`
`3750
`
`4850.5
`
`9063
`
`495
`705
`
`360
`840
`
`885
`885
`
`495
`1035
`
`510
`720
`
`1365
`
`60
`975
`
`240
`2010
`
`2970
`
`‐15
`1440
`
`1665
`
`60
`2250
`
`465
`1605
`
`180
`900
`
`225
`615
`
`797115
`25410
`429802
`51050
`
`749775
`2985
`480720
`51876
`
`715110
`1275
`581458
`59909
`
`698805
`570
`626106
`67585
`
`707115
`405
`695892
`71680
`
`692925
`75
`775710
`77438
`
`507665
`586454
`97313
`97801
`4440120 5262279
`
`474472
`103939
`6314552
`
`464997
`107908
`7161302
`
`292082
`350880
`89562
`97067
`7577134 7780541
`130
`1019
`90
`250
`992
`8978
`899
`2065
`
`731925
`102
`879887
`82598
`
`280261
`84217
`8230043
`2241
`199
`17027
`1588
`
`744420
`1
`992461
`91986
`
`744870
`777345
`30
`15
`1092363 1163251
`97555
`101468
`
`235294
`91914
`8326942
`2640
`173
`20331
`1064
`
`230432
`219419
`95706
`94078
`8203455 7907344
`3046
`3061
`121
`122
`21570
`23810
`783
`838
`
`782445
`405
`1278068
`113640
`
`224341
`97658
`8076370
`3401
`108
`25244
`689
`
`794700
`
`1325778
`108061
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`203734
`92823
`8093780
`3367
`84
`25385
`632
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`790155
`
`781680
`45
`1387600 1361348
`108076
`103228
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`173459
`171002
`88997
`91106
`7815788 7447117
`3371
`2496
`63
`66
`24360
`18598
`453
`319
`
`797325
`
`1435846
`111392
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`156630
`90805
`7796597
`2818
`70
`20457
`349
`95290
`
`732810
`135
`1457059
`107802
`
`155220
`103904
`7958778
`3321
`65
`21609
`374
`192240
`
`708645
`
`674985
`
`696270
`
`635205
`
`1462669
`111877
`
`167220
`98183
`7815917
`3439
`42
`21750
`352
`227050
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`1443635
`111120
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`177595
`98372
`7685043
`3242
`73
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`317
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`1496952
`120544
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`159381
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`7912472
`3395
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`140520
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`3190
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`632895
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`122250
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`195
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