6/29/2017
`
`Tiny patch 'dots' pharmaceutical iandscape | Packaging World
`
`
`
`
`Tiny patch 'dots' pharmaceutical iandscape | Packaging World
`
`
`
`
`×ØÙ-%0(Ù+Ú$'$Û()+Ü3)/0$%/#$%&$'()'Ý1Ø%$/(3)Þ+$1+0-()#$%&$'()'Ü$ß+)1$0ààààà+Ù()$0-
`
`
` !!!
`#$%&$'()')+,-./0+)1-2())34$/(3)-
`
`Subscribe Magazine Contract Packaging Education Leaders in Packaging Calendar Webinars
`Type in your search criteria...
`
`PACK EXPO SHOWS
`
`j DESIGN
`
`i MACHINERY
`
`i VIDEOS
`
`j CASE STUDIES
`
`j PLAYBOOKS
`
`GALLERIES
`
`September 25-27, 2017
`Las Vegas, Nevada USA
`
`COUNTDOWN TO
`PACK EXPO Las Vegas
`
`87 13
`Days Hours
`
`( REGISTER )
`
`RACK
`EXPO
`
`us VEGAS
`
`FUMSflK
`
`B"
`
`'i
`
`GLenroy invites
`you to download
`this playbook.
`
`Playbook jam-packed with strategies for success,
`best practices, and pitfalls to avoid. Learn more »
`
`©
`
`ARTICLE | DECEMBER 31,1999
`
`G+1
`
`0
`
`Noven Pharmaceuticals employs a new cartoner to help introduce an estrogen replacement
`therapy patch sold to pharmacies and merchandised free as physician samples.
`
`ÀÁÂÃÅÆÀÇÈÉÇÊÈ ËÅÈÌÍÎ ÏÁÂÉÌÎÅÐÑ ÒÌËÅÇÈ ÂÁÈÅÈÓÔËÌÅÈ ÀÕÁÑÖÇÇÃÈ ÍÁÕÕÅÐÌÅÈ
`TMUVWXTYDEFG6HEF Z@S
` C[\
`]W^_5`W]
`567869:6;=>?=@A=BC@
`DEFG6HEFAI6JEKEL5M OPQRSP RP
`abcdefbchijkilemlhnopcjqemqrc
`sonktuvwxyzw{|}~ {abcdefbcijkileml
`zywy}
`w}w|wxyzw{|
`Flexible packaging project in the
`}~z{ww
`(tmw m Download this free, 140-page Flexible Packaging
`works?
`bifook{{|x}~}{}w
`}{}{y|}{zz}w{w|cinmonc
` ¡¢£v¢ ¢¤¥¢¦ §§§
`B
`B
`B
`¼
`Tiny patch 'dots' pharmaceutical landscape
`¬wy~{{}{zzw{yx{}wy}w~zy}w|{y}wyz{y}
`}~{{}~wz|}w~{{{y|~{y||{~{y{z
`y}¢{z¾~{
`¤{~y½y}wy½ ~x~
`®¯e®«qtjrbe°aciq«nct±ªeqon
`}²yw}y{z}wwz}{y|{z{}~}w}w
`wyw}wz{yy{³wx}~´}~w~}~yµ
`|wyw}wyyw}{xzzywxyw~zyxwyw
`x}~yw{{z}w}~w~~}wy
`z{y}}~{¶¢·{}~~{y{{z{zy
`}~ §¸¹}~z{}¤{²z{y~wºzzvw}»¬wy
`~{{}{z~w}w~{y}~{}
`¬wy{{´w{}µ~{|wz|y{}wy
`y}|x}~{y}}wy{y|yywzw~}w
`yw}wyz{}~{{w{{zy}wxwy}{zw}wy}~{}w|}{z{}wy{y|{
`y|}{y|{z
`
`âãäåæçèçéêëìíìîçïðñòâãäåæçèçéêëìíìîçïðñò
`
!
!
`
`
`"
""
"
`
`
`By Jim Butschli, Features Editor
`It's not unusual to see people use transdermal patches to stop
`smoking or to relieve angina. However, this "through-the-skin"
`dosing option is not as well-known for helping women cope
`with menopausal symptoms, though such estrogen
`replacement therapy (ERT) patches have been available since
`the 1970s. With last May's launch of Vive lie-Dot™, Noven
`Pharmaceuticals hopes to change that.
`
`FILEDIN: Machinery > Inspection > Checkweighers
`
`Print Email Share
`
`w v*
`
`I to-
`
`H.
`
`Noven uses a makeup "compacf'-shaped folding carton,
`printed with usage instructions and feminine color schemes to
`not only make the package more appealing to women, but also to ensure that product application and usage is
`understandable.
`
`MYLAN - EXHIBIT 102 j
`/12
`https://www.packworld.com/article/machinery/inspection/checkweighers/tiny-patch-dots-pharmaceutical-landscape
`
`
`
`6/29/2017
`Tiny patch 'dots' pharmaceutical landscape | Packaging World
`A cartoner from R.A. Jones (Cincinnati, OH) is equipped with a Videojet 270i ink-jet printer from newly renamed
`Marconi Data Systems (Wood Dale, IL), that prints Lot and expiration date codes onto carton end flaps.
`
`These inner cartons are then manually loaded into one of two different outer folding cartons. One carton is used
`for sales to pharmacies where the product is sold by prescription only. Another carton is used to ship samples to
`physicians who can offer Vivelle-Dot to appropriate patients. Both the outer and inner folding cartons come from
`Vista Color (Miami, FL).
`
`Vivelle-Dot is manufactured and packaged at Noven Pharmaceuticals' Miami, FL, facility, an FDA-approved facility
`that follows cGMP guidelines. Noven and Novartis Pharmaceuticals Corp. of East Hanover, NJ, formed a joint
`venture, Novogyne Pharmaceuticals, to market Vivelle-Dot and other women's health products.
`
`Producing pouches
`
`That material is rewound and slit into 6"- or 8"-W rolls to accommodate downstream packaging equipment. Rolls
`are wrapped in film and foil to prevent debris from contacting the product as pallet loads of it are moved by forklift
`to the warehouse. The rolls are threaded through one of three horizontal die-cutting and pouching machines that
`have been running since the late '80s.
`
`The machines package a postage-stamp-sized patch between an upper and lower film web supplied by RJR
`Packaging (Winston-Salem, NC). The adhesive-lamination for both rolls consists of 26# paper/4# low-density
`polyethylene/0.0055 aluminum foil/11# LDPE. The material is heat-sealed on four sides, with cuts made between
`seal areas to create individual pouches. A lot and expiration date (two years from the blending date) are debossed
`into the seal area of the pouch.
`
`Pouches are then conveyed past a checkweigher. Before they're loaded into corrugated cases, quality assurance
`personnel inspect representative samples to confirm compliance to pouched product integrity. Once approved,
`pallet loads of case-packed pouches are brought to what's called a "cartoning suite," where individual pouches are
`automatically cartoned on the R.A. Jones machine.
`
`Bought in '98
`
`"We acquired the machine in 1998," says Huda Midani, Noven's project manager of operations. "It did not replace
`another machine. Instead, it was purchased to handle another hormone therapy patch. We also use it for the
`Vivelle-Dot product line. We run about 60n cartons a day on it," she notes, "at speeds of 100 to 120 per minute.
`The machine has done very well for us."
`
`Midani says, "When we were looking for a cartoner, we had choices, but we looked for a company with an excellent
`track record and the best available product."
`
`The product is made by Noven's Dot-Matrix™ technology, a process that blends adhesives with estradiol, the
`synthetic form of the estrogen hormone that's used to counter symptoms such as hot flashes and night sweats.
`That solution is blended, then coated onto a film release liner. Solvents from the adhesive are removed during the
`process, leaving behind a plasma-like substance rather than a liquid. The adhesive side of the product is then
`laminated to a coextruded plastic backing.
`
`
`
`
`N{}wyNwNNówyN¶ yyy{}Nô³·NNõ|Nx}~N{Nº|w}Nö¸Ny}Ny}NwNyxzNy{|
`¤{wyNv{}{N¾}N¶¹ww|Nv{zN¡·N}~{}Ny}Nzw}N{y|N÷{}wyN|{}Nw|Nwy}wN{}wyNy|Nø{
`~NyyN{}wyN{N}~yN{y{zzNzw{||Ny}wNwyNwN}xwN|y}Nw}Nwz|yN{}wyNôyN{}wyNN|
`wN{zN}wN~{{Nx~N}~Nw|}NNwz|NN}wyNwyzNyw}~N{}wyNN|N}wN~N{zN}w
`~{yNx~wN{yNwNºzzvw}N}wN{w{}N{}y}N¥w}~N}~Nw}N{y|NyyNwz|yN{}wyNwNw
`º}{N wzwN¶¤{Nù¡·
`ºzzvw}NN{y{}|N{y|N{{|N{}N¬wyN~{{}{z²N¤{Nù¡N{z}N{yNùv{w|N{z}
`}~{}NwzzwxN¤N|zyN¬wyN{y|N¬w{}N~{{}{zN wNwN¢{}N³{ywN¬óNw|N{Nwy}
`y}N¬wwyN~{{}{zN}wN{}Nºzzvw}N{y|Nw}~Nxwy²N~{z}~Nw|}
`noª«jemlgho«jrct
`~Nw|}NN{|NN¬wy²Nvw}¤{}÷»N}~ywzwN{NwN}~{}Nzy|N{|~Nx}~N}{|wzN}~
`y}~}NwNwN}~N}wyN~wwyN}~{}²N|N}wNwy}N}wN~N{N~w}Nø{~N{y|Ny~}Nx{}
`~{}Nwz}wyNNzy||N}~yNw{}|Nwy}wN{NúzNz{NzyN¾wzy}NwN}~N{|~N{Nw|N|yN}~
`wNz{yN~y|N{Nz{{zN}{yN{}~N}~{yN{Nzõ|N~N{|~N|NwN}~Nw|}NN}~y
`z{y{}|N}wN{Nw÷}||Nz{}N{y
`~{}N{}{zNNxwy|N{y|Nz}Ny}wNûµNwNüµ¹NwzzN}wN{ww|{}N|wxy}{N{{yNõy}Nwzz
`{Nx{|NyNúzN{y|NwzN}wNy}N|NwNwy}{}yN}~Nw|}N{N{zz}Nzw{|NwN}N{Nw|NNwz}
`}wN}~Nx{~wN~NwzzN{N}~{||N}~w~NwyNwN}~N~wýwy}{zN|}}yN{y|Nw~yN{~yN}~{}
`~{NyNyyyNyN}~Nz{}N²ü
`~N{~yN{{N{Nw}{}{ý|N{}~N}xyN{yNN{y|NzwxNúzNxNz|NNó
`{{yN¶¹y}wy¾{zN¬ ·N~N{|~z{y{}wyNwNw}~NwzzNwy}NwNöûþN{ þNzwx|y}
`wz}~zy ¦ N{zyNwz þN¡v¢N~N{}{zNN~{}{z|NwyNwN|Nx}~N}N{|N}xy
`{zN{{N}wN{}Ny||{zNw~NNzw}N{y|N÷{}wyN|{}N¶}xwN{NwN}~Nzy|yN|{}·N{N|w|
`y}wN}~N{zN{{NwN}~Nw~
`w~N{N}~yNwy|N{}N{N~x~N¥wN}~²Nzw{||Ny}wNw{}|N{Nõ{z}N{{y
`wyyzNy}Ny}{}N{zN}wNwyúNwz{yN}wNw~|Nw|}Ny}}NôyN{w|
`{zz}Nzw{|NwN{{|Nw~N{Nw~}N}wNx~{}²N{zz|N{N´{}wyyN}µNx~Ny||{zNw~N{
`{}w{}{zzN{}wy|NwyN}~NNówyN{~y
`®o«lrqgemg
`´¹N{õ|N}~N{~yNyN §§üµN{N³|{N¤|{yN¬wy²Nw}N{y{NwNw{}wyN´}N||Nyw}Nz{
`{yw}~N{~yNy}{|N}Nx{N~{|N}wN~{y|zN{yw}~N~wwyN}~{N{}~N¹N{zwNN}NwN}~
`ºzzvw}Nw|}NzyN¹NyN{w}NûN{}wyN{N|{NwyN}µN~Nyw}N´{}N|NwN N}wN öNNy}
`~N{~yN~{N|wyNNxzzNwNµ
`¤|{yN{N´¹~yNxNxNzwwyNwN{N{}wyNxN~{|N~wN}NxNzww|NwN{Nw{yNx}~N{yN÷zzy}
`}{Nw|N{y|N}~N}N{{z{zNw|}µ
`
!
!
`
`
`"
""
"
`
`https://www.packworld.com/article/machinery/inspection/checkweighers/tiny-patch-dots-pharmaceutical-landscape
`
`
`
`2/12
`
`
`
`6/29/2017
`Tiny patch 'dots' pharmaceutical landscape | Packaging World
`The ink-jet coder on the cartoner prints Lot and expiration date onto an end flap of the individual folding carton
`(IFC). From Vista Color, the CIS, 18-pt SBS carton is offset-printed in three colors plus varnish.
`
`Different configurations
`
`For physician samples, the cartoner loads two patches/carton. "That's one week's supply," says Natalie Rajcoomar,
`product manager, marketing and sales. For pharmacies, eight patches (one month's worth) are packed into the IFC.
`
`"We use the same carton for either two patches or eight for different reasons," Midani explains. "When the
`physician or nurse gives the carton with two patches to the patient, we want to familiarize the consumer with the
`package that she would receive from the pharmacy.
`
`"We also want her to know that when she opens the main carton flap she'll see the compliance 'calendar' that's
`printed on the inside flap," she continues. "This calendar has check boxes that list two days of the week, such as
`Sun/Wed, so that the woman checks the date she first applied the patch, say on a Sunday, and can see that she'll
`need to remove that patch and replace it with a new one on Wednesday."
`
`Using the same IFC for both markets has advantages for Noven that go beyond familiarizing users with the package
`and assisting them with compliance issues. "From a packaging perspective, we wanted to keep our changeovers on
`the Jones machine to a minimum," Midani says. "If we maintain a package size that's consistent, it requires fewer
`machine adjustments. That results in greater operating efficiencies and less downtime."
`
`After the machine erects the carton and tucks in the end flaps of one carton side, it loads the pouches into the
`carton. A friction feeder from Longford Equipment (Scarborough, Ontario, Canada) dispenses two printed, folded
`and glued paper inserts into the IFC. Then the R.A. Jones machine closes the end flaps. One insert is a physician's
`insert that carries information such as the product's chemical name; the other provides product information such as
`application instructions for the end user. Both inserts are required by FDA.
`
`
`
`
`~Ny}Nw|NwyN}~N{}wyNy}Nzw}N{y|N÷{}wyN|{}Nwy}wN{yNy|Nø{NwN}~Ny||{zNwz|yN{}wy
`¶ù ·NùwNº}{N wzwN}~N ¾N ü}N¾¥¾N{}wyNNw}y}|NyN}~NwzwNzN{y~
`}N}~N{~yN}N}~N{}wyN{y|N}NyN}~Ny|Nø{NwNwyN{}wyN|N}Nzw{|N}~Nw~Ny}wN}~
`{}wyNN}wyN|NwN¡wyw|N¢õy}N¶¾{ww~Nôy}{wN {y{|{·N|yN}xwNy}|Nwz||
`{y|Nz|N{Ny}Ny}wN}~Nù N~yN}~NNówyN{~yNzwN}~Ny|Nø{NôyNy}NN{N~{y²
`y}N}~{}N{Nyw{}wyN~N{N}~Nw|}²N~{zNy{N}~Nw}~Nw|Nw|}Nyw{}wyN~N{
`{z{}wyNy}}wyNwN}~Ny|NN¥w}~Ny}N{Nõ|NNùv
`ecncmqgjom l«niqeomt
`ùwN~{yN{zN}~N{}wyNzw{|N}xwN{}~ {}wyN´~{}²NwyNx²NzµN{N¬{}{zN{ww{
`w|}N{y{N{}yN{y|N{zNùwN~{{N~}N{}~N¶wyNwy}~²Nxw}~·N{N{|Ny}wN}~Nù
`´¹NN}~N{N{}wyNwN}~N}xwN{}~NwN~}NwN|y}N{wyµN¤|{yN÷z{yN´¹~yN}~
`~{yNwNyNN}~N{}wyNx}~N}xwN{}~N}wN}~N{}y}NxNx{y}N}wN{z{ýN}~NwyNx}~N}~
`{{N}~{}N~Nxwz|NNwN}~N~{{
`´¹N{zwNx{y}N~N}wNywxN}~{}Nx~yN~NwyN}~N{yN{}wyNø{N~²zzNN}~Nwz{yN
`{zy|{²N}~{}²
`y}|NwyN}~Ny|Nø{µN~Nwy}yN´~N{zy|{N~{N~Nw÷N}~{}Nz}N}xwN|{NwN}~NxN~N{
`¾y ¹|NwN}~{}N}~Nxw{yN~N}~N|{}N~Nú}N{z|N}~N{}~N{NwyN{N¾y|{N{y|N{yNN}~{}N~²zz
`y|N}wNwN}~{}N{}~N{y|Nz{N}Nx}~N{NyxNwyNwyN¹|y|{µ
`
` yN}~N{Nù NwNw}~N{}N~{N{|{y}{NwN¬wyN}~{}NwNwy|N{z{ýyNNx}~N}~N{{
`{y|N{}yN}~Nx}~Nwz{yNN´ùwN{N{{yN}NxNx{y}|N}wNNwN~{ywNwy
`}~NówyN{~yN}wN{NyµN¤|{yN{N´NxN{y}{yN{N{{NýN}~{}²Nwy}y}N}NõNx
`{~yN{|}y}N~{}Nz}NyN{}Nw{}yNúyN{y|NzN|wxy}µ
`
`
inqomgjribbcmlct
`ôyyN}~N{}wy²N}wNø{N{zN{Nw{}|N{N}wyN}~{}NN{}NwN}~Nù N~N{yzNyz|N{}y}
`y}}wyN{y|NNzz|NwyN}wNw|N{N}wN}~Nw~|N{}NyN}~N{}wy
`´~N{}NwN}~N{}wyNx{N~{zzyyNwN{N|yN}{y|wy}µN{N¤|{yN´¹Nx{y}|N}~Nw{}wyN}wN
`}wyNyw~N}wN{w|Nwzz{Ny|Ny{zN}N}N}~Nw{}wyNwz|y²}NNwN|N}~{}NzzyN}~
`wyN{Ny}}|Nxwz|NN}~N{}wy²N|N{yzN~Nx{N{Nwy|{zN{wy}NwN}N{y{zN|wy
`y}zNxNw}N}N}N~}N}²N{NyõN{{N}~{}NxNN}wN{N{N}{~}}Nw{}}zN{}wyµ
` «qcngjinqomgªecncmjct
`¹~zN}~Nw~N{y|Nù N{N}~N{NwNw}~Nºzzvw}N}{}N{}N}~NN|y}Nw}Nwz|yN{}wy
`ùwN}~N~{yN{zN}~N´|z{N{µN{N}~NwzwzNzN{~N{y|N~wz|NúNù NNz
`x~}{y|zN{~N~NN|NwN}~N~{{N´}{|N{µNx~~N~wz|N}~Nù
`´~²NwNwN{N{}yN}{}NyN{{zyN}wN}~N~{yN{NxN~{N}wNwyyN}~N}~{}Nw
`w|}NN}~N}µN{N¤|{yN¥|NyNwNwzwzN{~N}~N|z{N{Nyz|N{N´wµNø{
`}~{}Nwz|NN{y|N}Ny}wN}~N{}wyN~y|N}~N}~Nù N¾}NN}~N{}wyN}{NwyN{N}{zzN{{{y
`}~{}N{N}N{yN{{zyN{||}wyN}wN}~N~{y²NwúN~{}NN{{zNNyy{NyN~{{
`
`ôyyN}~N{}wy²N}wNø{N{zN{Nw{}|N{N}wyN}~{}NN{}NwN}~Nù N~N{yzNyz|N{}y}
`y}}wyN{y|NNzz|NwyN}wNw|N{N}wN}~Nw~|N{}NyN}~N{}wy
`´~N{}NwN}~N{}wyNx{N~{zzyyNwN{N|yN}{y|wy}µN{N¤|{yN´¹Nx{y}|N}~Nw{}wyN}wN
`}wyNyw~N}wN{w|Nwzz{Ny|Ny{zN}N}N}~Nw{}wyNwz|y²}NNwN|N}~{}NzzyN}~
`wyN{Ny}}|Nxwz|NN}~N{}wy²N|N{yzN~Nx{N{Nwy|{zN{wy}NwN}N{y{zN|wy
`y}zNxNw}N}N}N~}N}²N{NyõN{{N}~{}NxNN}wN{N{N}{~}}Nw{}}zN{}wyµ
` «qcngjinqomgªecncmjct
`¹~zN}~Nw~N{y|Nù N{N}~N{NwNw}~Nºzzvw}N}{}N{}N}~NN|y}Nw}Nwz|yN{}wy
`ùwN}~N~{yN{zN}~N´|z{N{µN{N}~NwzwzNzN{~N{y|N~wz|NúNù NNz
`x~}{y|zN{~N~NN|NwN}~N~{{N´}{|N{µNx~~N~wz|N}~Nù
`´~²NwNwN{N{}yN}{}NyN{{zyN}wN}~N~{yN{NxN~{N}wNwyyN}~N}~{}Nw
`w|}NN}~N}µN{N¤|{yN¥|NyNwNwzwzN{~N}~N|z{N{Nyz|N{N´wµNø{
`}~{}Nwz|NN{y|N}Ny}wN}~N{}wyN~y|N}~N}~Nù N¾}NN}~N{}wyN}{NwyN{N}{zzN{{{y
`}~{}N{N}N{yN{{zyN{||}wyN}wN}~N~{y²NwúN~{}NN{{zNNyy{NyN~{{
`
!
!
`
`
`"
""
"
`
`
`Carton challenges
`
`Opening the carton's top flap reveals a perforated paper section that is part of the IFC. This panel includes patient
`instructions and is pulled open to provide access to the pouched packets in the carton.
`
`"This part of the carton was challenging from a design standpoint," says Midani. "We wanted the perforations to be
`strong enough to avoid collapse under minimal stress, but the perforations couldn't be so rigid that pulling them
`open as instructed would rip the carton's side panels. There was a considerable amount of stress analysis done
`until we got it just right. It's a unique package that we refer to as a straight-tuck, compact-style carton."
`
`Outer carton differences
`
`While the pouch and IFC are the same for both Vivelle-Dot target markets, they use different outer folding cartons.
`For the physician sampler, the "display packer" carries the colorful purple graphics and holds five IFCs. A simpler
`white-and-blue graphics scheme is used for the pharmacy "trade packer," which holds three IFCs.
`
`"There's more of a marketing strategy in appealing to the physicians because we have to convince them that our
`product is the best," says Midani. Besides using more colorful graphics, the display packer includes a "pop-up" flap
`that folds up and tucks into the carton behind the three IFCs. Set up, the carton takes on a retail-like appearance
`that makes it an appealing addition to the physician's office. That eye appeal is unnecessary in pharmacies.
`
`https://www.packworld.com/article/machinery/inspection/checkweighers/tiny-patch-dots-pharmaceutical-landscape
`
`3/12
`
`
`
`6/29/2017
`Tiny patch 'dots' pharmaceutical landscape | Packaging World
`Both of these outer cartons are again supplied by Vista Color. Like the IPCs, the trade packer consists of CIS, 18-pt
`SBS, offset-printed in three colors plus varnish. (The display packer is 20-pt SBS.) The purple color on the IPC and
`physician display box "looks feminine and differentiates it from our previous Vivelle® patch, which came in a larger
`teal-colored carton," says Rajcoomar. She points out that the new Vivelle-Dot is 66% smaller than the size of the
`Vivelle patch.
`
`
`
`
`¥w}~NwN}~Nw}N{}wyN{N{{yNz|NNº}{N wzwN¡N}~Nù N}~N}{|N{Nwy}NwN ¾N ü}
`¾¥¾Nw}y}|NyN}~NwzwNzN{y~N¶~N|z{N{NNö}N¾¥¾·N~NzNwzwNwyN}~Nù N{y|
`~{yN|z{Nw÷N´zwwNyyN{y|N|y}{}N}NwNwNwNºzzN{}~Nx~~N{NyN{Nz{
`}{zwzw|N{}wyµN{N{ww{N¾~Nwy}Nw}N}~{}N}~NyxNºzzvw}NNûûN{zzN}~{yN}~NýNwN}~
`ºzzN{}~
`tctgbcttgiqcneib
`~N{}~NýN~{N{yNw}Nz{}wyNwN¬wwyN}N}wN{y|Nw|}NNùwN÷{zNwyN}~
`ºzzvw}Nx}~N Nzz{ |{N|w{N¶}~N{NwN}y}~N{}·N}~N{}~N{N NöN{
`w{|N}wN NöNwyN}~NºzzNwyNvzyN}~N{N|w{NyN{N{zzN{}~Nx{NwzN{
`wN}~Nvw}¤{}÷N{y{}yN}~ywzwN~N{zzN{}~NNwNww}{zN}wNx{NzNw}N{y|N
`÷}wy{zzN{|~y}
`N{zzN{}~N{zwN{yN}~Nw~N{yNN{zzNùwN}~N N|wN}~Nºzzvw}Nw~N{Nö
`µ÷öNµN{Nw{|N}wNöN¸ üµ÷öN¸ üµNwN}~NºzzN{}~N¹}~Nz{N|w{N}~N{{NýN|y
`y{N¾z{N{{NýN|}wyNwNwN}~Nù Nw}Nwz|yN{}wyN{y|Nw{}|N~N|
`wNºzzvw}N¤|{yN}{}N{{yN{}{zN{yNwN¦üNx}~Nºzzvw}Nw{|Nx}~N{}{z
`y{N}wN{{Nºzz
`´{y|{zN{N|y|N{}N~{{NyN}~Nwy{zN{{yN}~wNwN{{yNN|y|Nx}~
`w|}Ny}}N{y|Nw}}wyNyNwyN{y|NyN}xwN}wN{{zN}wNwN{zN}{}N{}µN{N¤|{y
`¾~N{N}~{}N´yN}Nz{y~Nºzzvw}N~{N{y|NúNy}NyNyxN{}N~{Nz}~w~N}²N|úz}N}w
`{N~wxN~NwN}~NNN|N}wN{{yN}~N{{yN|yNNyNNxzzNôNúz|NN{
`|z~}|N{}Ny}yN}~N{{N}wN}~N~{yN}wN~NN~{N|N{}N|{N{y|
`~{{N{Nz{|N}wN|z{N}~Nw|}N{N}N}{NNzN~zN{N}~{yN|wNºzzµ
`mgigr«nnugc«ctqgoncgemogeigcffitcªgnciªcngtcnejcgfgjbejkemlgomgjohim
`mic ! "#$ %!&' ()*+ + +*,( -,. /(+, (0 (+1/ 2(/+,34
`® 5±g67g± 5ga 8g± ¯±¨g¨±
9:
;±5g:
`J
`rfir
`\
` á =
`>?@
`
ohimectgemgqretginqejbc<
`¾ ¡¢¾eªcopcqg¨cjrmobolectgmj
`
`
`¾ ¡¢¾eªcopcqg¨cjrmobolectgmj
`
`
!
!
`
`
`"
""
"
`
`K
`0 P
`>? EE F A
`
`
`G H A B CD
`I ?
`E
`
`Videojet 9550 Print & Apply
`Labeler in Action @ Pack Expo
`2015
`
`Wolke nn600 oem Thi
`Inkjet Printer
`
`Uses less material
`
`The patch size has many positive implications for Novogyne, its customers and product users. Por example, on the
`Vivelle-Dot with 0.05 milligram/day dosage (there are four strength varieties), the patch measures 5 cm2 as
`compared to 14.5 cm2 on the Vivelle version. Delivering the same dosage in a smaller patch was possible because
`of the Dot-Matrix manufacturing technology. The smaller patch is more comfortable to wear, less obtrusive and is
`exceptionally adherent.
`
`A smaller patch also means the pouch can be smaller. Por the 0.05-mg dose, the Vivelle-Dot pouch measures 2
`Vi"x2 Vi" as compared to 2 7/8"x2 7/8" for the Vivelle patch. With larger dosages, the package size difference
`increases. Similar package size reductions come from the IPC, outer folding cartons and corrugated shippers used
`for Vivelle-Dot. Midani estimates packaging material savings of 58% with Vivelle-Dot compared with materials
`necessary to package Vivelle.
`
`"Transdermals are dispensed at pharmacies in their original packaging, therefore, our packaging is designed with
`product integrity and protection number one, and number two to appeal to our female target market," says Midani.
`
`She says that "since its launch, Vivelle-Dot has gained five percent in new market share. Although it's difficult to
`assess how much of this success is due to packaging, the packaging design is serving us well. Our field reps are
`delighted at presenting these packages to their physician customers. The reps have received great feedback and
`pharmacies are pleased to display the product because it takes up less shelf space than does Vivelle."
`
`In a hurry? Request more info via Web-based reader service by clicking on company
`name.
`Or you can jump right to their Web site if it's listed.
`
`BROWSE 46 VIDEOS FROM VIDEOJET TECHNOLOGIES INC.
`
`<
`
`Holiday Greetings from
`Videojet!
`
`>? O O A
`B CD
E
`
`Videojet Case Coding in Action
`@ Pack Expo 2015
`
`Companies in this article:
`
`SUPPLIERS: » Videojet Technologies Inc.
`
`https://www.packworld.com/article/machinery/inspection/checkweighers/tiny-patch-dots-pharmaceutical-landscape
`
`
`
`4/12
`
`
`
`Videojet Case Coding in Action
`@ Pack Expo 2015
`
`Companies in this article:
`
`SUPPLIERS: » Videojet Technologies Inc.
`
`https://www.packworld.com/article/machinery/inspection/checkweighers/tiny-patch-dots-pharmaceutical-landscape
`
`
`
`4/12
`
`
`
`
`
`6/29/2017
`
`
`
`
`Tiny patch 'dots' pharmaceutical iandscape | Packaging World
`
`» Oystar Jones
`» Longford International LTD
`» RJR Packaging, a div. of RJ. Reynolds Tobacco Co.
`» Marconi Data Systems
`
` tqin¯omct
`omlonªmqcnmiqeomib¨
`¯ijkileml°iªeo¯cmobªt¨ofijjo
o
`8injomeiqi5tqct
`eªmLq mªsriqo«Lncbookemlonu
`zzx~{}wy|{y|xxzzyw}wxz{y~{w|}w~{yw{}wy}~{}{y~z
`wM
`O±ieb<
`rejrfctqªctjnefctsriqo«Lncbookemlon<
`O {~yzw{w}
`¡wwywy|}}{}}
`¡wwywywwyw}}w
`ô}~
`Obcitccdhbiememªcqiebsriqo«incbookemlon<
`rfctqªctjnefcto«njohim<
`O ¹{{{w|}¶wwxywww}~·
`¹zz{{y¶{~y{}{z·
`ô}~y}}|{}
`5P:9Q8
`y||{zwyyw}{{y}|
`PACMPJ1
`om©qettemqcbbelcmjcjn«jeibqoo«npofimªf«temcttN
`¾z}wy}}{{zwx
`
`8injomeiqi5tqct
`eªmLq mªsriqo«Lncbookemlonu
`zzx~{}wy|{y|xxzzyw}wxz{y~{w|}w~{yw{}wy}~{}{y~z
`wM
`O±ieb<
`rejrfctqªctjnefctsriqo«Lncbookemlon<
`O {~yzw{w}
`¡wwywy|}}{}}
`¡wwywywwyw}}w
`ô}~
`Obcitccdhbiememªcqiebsriqo«incbookemlon<
`rfctqªctjnefcto«njohim<
`O ¹{{{w|}¶wwxywww}~·
`¹zz{{y¶{~y{}{z·
`ô}~y}}|{}
`5P:9Q8
`y||{zwyyw}{{y}|
`PACMPJ1
`om©qettemqcbbelcmjcjn«jeibqoo«npofimªf«temcttN
`¾z}wy}}{{zwx
`
!
!
`
`
`"
""
"
`
`Didn't find what you're Looking for?
`TeLL us what you need and we wiLL notify you if we launch a product or have information that can help
`you!
`
`Email:
`
`Which best describes what you're looking for:
`
`Researching suppliers for a project
`
`Looking for industry statistics
`
`Looking for info on competitors
`
`Other
`
`Please explain in detail what you are looking for:
`
`Which best describes your company:
`
`We package a product (our own or for others)
`
`We sell packaging (machinery, materials)
`
`Other interested party
`
`Submit
`
`Individual responses not guaranteed.
`
`A
`
`Don't miss intelligence crucial to your job and business!
`Select your interest areas below.
`
`https://www.packworld.com/article/machinery/lnspection/checkwelghers/tiny-patch-dots-pharmaceutlcal-landscape
`
`E
`
`5/12
`
`
`
`
`
`6/29/2017
`
`Packaging news and trends
`
`Package design/development
`
`Contract Packaging
`
`Packaging Line engineering
`
`{{yyx{y|}y|
`{{|y |zwy}
` wy}{}{{y
`{{yzyyyy
`RQSROTISC
`
`
`
`
`Tiny patch 'dots' pharmaceutical iandscape | Packaging World
`
`( SUBSCRIBE )
`
`LEADERS
`ookemlonbciªemlt«hhbecntu
`¤ww}w}~w{y
`:5±
¨U5
:U¨±5¨:;U
9±
V±;9
`Wbbaebbmj
`
`Wbbaebbmj
`
!
!
`
`
`"
""
"
`
`KIN PACKAGING
`Looking for Leading suppliers?
`Mouse over to see these companies;
`
`INSPECT/VISION/TESTING/CHECKWEIGH
`
`[f All-Fill Inc.
`
`https://www.packworld.com/article/machinery/inspection/checkweighers/tiny-patch-dots-pharmaceutical-landscape
`
`
`
`6/12
`
`
`
`
`
`6/29/2017
`
`Tiny patch 'dots' pharmaceutical iandscape | Packaging World
`
`d? Anritsu Infivis Inc.
`[f Cognex Corporation
`[f Fortress Technology
`[f Heat and Control, Inc.
`d? Keyence Corp. of Americ...
`[f Leibinger
`[f Matrox Imaging
`[f Mettler Toledo
`c Thermo Fisher Scientifi...
`[P WIPOTEC-OCS, Inc.
`:Z Yamato Corporation
`
`
`
`Wmneqt«m etmj
`
olmcd
onhoniqeom
`aonqnctt¨cjrmobol
`9ciqimª
`aonqnctt¨cjrmobol
`9ciqimª
omqnob°mj
`Vccmjc
`Vccmjc
onhoWcnej
`cefemlcnn
`8iqnodileml
`8cqqbcn¨obcªo
`¨rcnoaetrcn5jecmqe
` ¨±
`cefemlcnn
`8iqnodileml
`8cqqbcn¨obcªo
`¨rcnoaetrcn5jecmqe
` ¨±
5°mj
`[iiqo
`[iiqo
onhoniqeom
`a 8UaU5±W9 X :¨WY
`a 8UaU5±W9 X :¨WY
9±5
®W;5Z
`Wbbijkileml8ijremcn
`®±«ehcmq
`®niªimikcmj
`«niimq
`aonotqa«pe
`Wbbijkileml8ijremcn
`®±«ehcmq
`®niªimikcmj
`«niimq
`aonotqa«pe
onhoniqeo
`;;Wijkileml°eeteom
`9inhik8Wijkileml°
`8W558W:W«qoiqeomcte
`5bccknihhcn
`celrhijk5tqctmj
`
`;;Wijkileml°eeteom
`9inhik8Wijkileml°
`8W558W:W«qoiqeomcte
`5bccknihhcn
`celrhijk5tqctmj
`
W¨
::;
`Wilinª;no«h°
`Wilinª;no«h°
`W
8im«ijq«neml
`®b«cnemqW«qoiqeom
`®otjrijkileml¨cjrmob
`®niªimikcmj
`
`®b«cnemqW«qoiqeom
`®otjrijkileml¨cjrmob
`®niªimikcmj
`
W8W;no«h
`cbkon5tqct°mj
`
`cbkon5tqct°mj
`
!
!
`
`
`"
""
"
`
`FORM/FILiySEAL - HORIZONTAL (POUCHES OR BAGS)
`
`[f All Packaging Machinery
`[f BPI Equipment
`d? Bradman Lake Inc.
`[P Duravant
`:Z Formost Fuji Corporatio...
`[f GGA Packaging, Division...
`[? Harpak-ULMA Packaging,...
`dP MASSMAN Automation Desi...
`dP Sleek Wrapper
`[f Weighpack Systems Inc.
`
`CARTONING
`
`d? Aagard Group, LLC
`ADCO Manufacturing
`dP BluePrint Automation
`[f Bosch Packaging Technol...
`dp Bradman Lake Inc.
`dP CAMA Group
`dP Delkor Systems, Inc.
`
`https://www.packworld.com/article/machinery/inspection/checkweighers/tiny-patch-dots-pharmaceutical-landscape
`
`
`
`7/12
`
`
`
`
`
`6/29/2017
`
`Tiny patch 'dots' pharmaceutical iandscape | Packaging World
`
`d? Douglas Machine Inc.
`[f Econocorp Inc.
`[f EOL Solutions
`[f Exair Corporation
`d? Graco Inc.
`[f Graphic Packaging Intl.
`Kliklok-Woodman
`MG America
`S1 Molins Langen
`dP Nordson Corporation
`d? Nuspark Inc.
`[f Optima Machinery Corp.
`d? PMI Cartoning
`[f Propack Processing and...
`[f Serpa Packaging Solutio...
`dp Somic America, Inc.
`dP Triangle Package Machin...
`dP WestRock
`
`
`
`o«lbit8ijremcmj
`±jomojonhmj
`± 5ob«qeomt
`±dien
onhoniqeom
`;nijomj
`;nihrejijkilemlmqb
`Vbekbokooªim
`8;Wcneji
`8obemtimlcm
`:onªtom
`;nijomj
`;nihrejijkilemlmqb
`Vbekbokooªim
`8;Wcneji
`8obemtimlcm
`:onªtom
onhoniqeom
`:«thinkmj
` hqei8ijremcn
`:«thinkmj
` hqei8ijremcn
onh
`8
`8
inqomeml
`nohijknojcttemlimª
`5cnhiijkileml5ob«qeo
`5oejWcneji°mj
`¨neimlbcijkilc8ijrem
`ctqojkk
`
`nohijknojcttemlimª
`5cnhiijkileml5ob«qeo
`5oejWcneji°mj
`¨neimlbcijkilc8ijrem
`ctqojkk
`
:¨W:±9W::;Ua±±:;U:5
W8®:;
`®ibªon±bcjqnej
`®ibªon±bcjqnej
ohim
`
`
55mqcnmiqeomibb
`
`
¨8ifcbeml5tqct°
`WVWcnejit
`±nec]8ilmcqejt
`;inc
`WVWcnejit
`±nec]8ilmcqejt
`;inc
onhoniqeom
`;nihrejijkilemlmqb
`W:;;¨9Wcnejiqª
`8iqcneib¨nimtcn
`8onnetom
`;nihrejijkilemlmqb
`W:;;¨9Wcnejiqª
`8iqcneib¨nimtcn
`8onnetom
omqiemcn9imª
`:ibfijr±mlemccneml
`:ibfijr±mlemccneml
o
`:iqeomib®«bk±«ehcmq
`
`:iqeomib®«bk±«ehcmq
`
!
!
`
`
`"
""
"
`
`CONTAINER HANDLING/FEEDING/UNSCRAMBLING
`
`dP Baldor Electric Company
`dP CSS International
`dP CTM Labeling Systems, I...
`dP DAK Americas
`dP Eriez Magnetics
`dP Garvey Corporation
`dP Graphic Packaging Intl.
`@ LANGGUTH America Ltd.
`dP Material Transfer...
`dP Morrison Container Hand...
`dP Nalbach Engineering Co.
`dP National Bulk Equipment...
`
`https://www.packworld.com/article/machinery/inspection/checkweighers/tiny-patch-dots-pharmaceutical-landscape
`
`\
`
`8/12
`
`
`
`
`
`6/29/2017
`
`Tiny patch 'dots' pharmaceutical iandscape | Packaging World
`
`$ New England Machinery,...
`[? PFLow Industries Inc.
`& PHD, Inc.
`d? Regal Power Transmissio...
`[f Ryson International, In...
`[? Shibuya Hoppmann Corpor...
`[f Simplimatic
`[f Spee-Dee Packaging Mach...
`
`CARTONS AND BOXES
`
`d? Bennett
`$ Fibre Box Association
`[? Graphic Packaging Intl.
`® HLP Klearfold
`[f Iconotech
`^ Paperworks Industries
`Redimark
`^ Transparent Container C...
`Uline
`Wexxar/BEL
`[f WS Packaging Group, Inc...
`
`FLEXIBLE PACKAGING
`
`® ACPO
`^ Automated Packaging Sys...
`^ Bemis Company, Inc.
`[f1 Charter NEX Films
`Constantia Flexibles Gm...
`[f Coveris
`[f CP Flexible Packaging S...
`[f Fres-co System USA
`[f Glenroy Inc.
`
`
`
`:cs±mlbimª8ijremcn°
`abosmª«tqnectmj
`9°mj
`cliboscn¨nimtetteo
`tommqcnmiqeomib°m
`5ref«i9ohhimm
onhon
`5ehbeiqejj
`5hccccijkileml8ijr
`
`5ehbeiqejj
`5hccccijkileml8ijr
`
W¨
:5W:®
^±5
`®cmmcqqq
`aefnc®odWttojeiqeom
`;nihrejijkilemlmqb
`9Vbcinobª
`jomoqcjr
`ihcnonktmª«tqnect
`cªeink
`¨nimthincmq
`®cmmcqqq
`aefnc®odWttojeiqeom
`;nihrejijkilemlmqb
`9Vbcinobª
`jomoqcjr
`ihcnonktmª«tqnect
`cªeink
`¨nimthincmq
omqiemcn
`bemccddinU®±
`5ijkileml;no«h°mj
`a±^®±W
VW;:;
`W
`W
W«qoiqcªijkileml5t
`®cet
`®cet
ohim°mj
`
`
rinqcn:±^aebt
`
`
omtqimqeiabcdefbct;
`
`
ocnet
abcdefbcijkileml5
`anctjo5tqc5W
`;bcmnomj
`
`anctjo5tqc5W
`;bcmnomj
`
!
!
`
`
`"
""
"
`
`https://www.packworld.com/article/machinery/inspection/checkweighers/tiny-patch-dots-pharmaceutical-landscape
`
`
`
`9/12
`
`
`
`Tiny patch 'dots' pharmaceutical iandscape | Packaging World
`
`d? MASSMAN Automation Desi...
`[f Overnight Labels, Inc.
`[f Phoenix Closures
`[f Printpack Inc.
`0 STA LLC
`
`
`
`8W558W:W«qoiqeomcte
`
` cnmelrqifcbt°mj
`rocmed
bot«nct
`nemqhijkmj
`5¨W
`nemqhijkmj
`5¨W
`W5¨
5U±5:5
`WVWcnejit
`Vemlbitqej
`WVWcnejit
`Vemlbitqej
onhoniqeo
`cefemlcnn
`VIDEO
`
`
`
`6/29/2017
`
`PLASTICS/RESINS
`
`^ DAK Americas
`[f King Plastic Corporatio...
`[f Leibinger
`
`•
`
`
`cefemlcnn
`VIDEO
`
`
`
`6/29/2017
`
`PLASTICS/RESINS
`
`^ DAK Americas
`[f King Plastic Corporatio...
`[f Leibinger
`
`•
`
`
`_cbccqimosem`emefbojktL
`
`» Velveeta now in 'mini blocks'
`
`720p
`
`
`
`1:37
`
`5WWMDDG_aWY5b
`
`SEE ALL VIDEOS »
`
`
!
!
`
`
`"
""
"
`
`https://www.packworld.com/article/machinery/inspection/checkweighers/tiny-patch-dots-pharmaceutical-landscape
`
`
`
`10/12
`
`
`
`
`
`6/29/2017
`
`
`
`
`Tiny patch 'dots' pharmaceutical landscape | Packaging World
`
`MAGAZINES
`
`ÏÁÍÁcÌÎÅÈ
`
`pncKHmnc>+
`PBOCEBBinC
`
`Heafthcare*
`
`p * i r i j i r i A ; s 3
`
`NATURE INSPIRES
`'WOUND CAflE WEB'
`
`K V
`
`.
`
`Country *
`- Select -
`
`
o«mqngdefghihjkfeáC lPQT mTCC RQSROTIIPR
`
`GET YOUR FREE SUBSCRIPTION
`
`
`
`GET YOUR FREE SUBSCRIPTION
`
`
!
!
`
`
`"
""
"
`
`https://www.packworld.com/article/machinery/inspection/checkweighers/tiny-patch-dots-pharmaceutical-landscape
`
`
`
`11/12
`
`
`
`
`
`6/29/2017
`
`
`
`
`Tiny patch 'dots' pharmaceutical landscape | Packaging World
`
`Packaging World @packagingworld
`
`Pat Reynolds @Packcentric
`
`J.
`
`Jim Butschli @PackagingDr
`
`Anne Marie Mohan @packagingtrends
`
`Magazine
`
`Conferences
`
`» Subscribe
`» Advertise
`>} About
`» R
Accessing this document will incur an additional charge of $.
After purchase, you can access this document again without charge.
Accept $ Charge
Still Working On It
This document is taking longer than usual to download. This can happen if we need to contact the court directly to obtain the document and their servers are running slowly.
Give it another minute or two to complete, and then try the refresh button.
A few More Minutes ... Still Working
It can take up to 5 minutes for us to download a document if the court servers are running slowly.
Thank you for your continued patience.
This document could not be displayed.
We could not find this document within its docket. Please go back to the docket page and check the link. If that does not work, go back to the docket and refresh it to pull the newest information.
Your account does not support viewing this document.
You need a Paid Account to view this document. Click here to change your account type.
Your account does not support viewing this document.
Set your membership
status to view this document.
With a Docket Alarm membership, you'll
get a whole lot more, including:
- Up-to-date information for this case.
- Email alerts whenever there is an update.
- Full text search for other cases.
- Get email alerts whenever a new case matches your search.
One Moment Please
The filing “” is large (MB) and is being downloaded.
Please refresh this page in a few minutes to see if the filing has been downloaded. The filing will also be emailed to you when the download completes.
Your document is on its way!
If you do not receive the document in five minutes, contact support at support@docketalarm.com.
Sealed Document
We are unable to display this document, it may be under a court ordered seal.
If you have proper credentials to access the file, you may proceed directly to the court's system using your government issued username and password.
Access Government Site
