Overdose Death Rates | National Institute on Drug Abuse (NIDA)
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`Page 1 of 9
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`Home » Related Topics » Trends & Statistics » Overdose Death Rates
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`Overdose Death Rates
`
`Revised September 2017
`
`The U.S. government does not track death rates for every drug. However, the National
`Center for Health Statistics at the Centers for Disease Control and Prevention does collect
`information on many of the more commonly used drugs. The CDC also has a searchable
`database, called CDC Wonder.
`
`Drugs Involved in U.S. Overdose Deaths * - Among the more
`than 64,000 drug overdose deaths estimated in 2016, the
`sharpest increase occurred among deaths related to fentanyl and
`fentanyl analogs (synthetic opioids) with over 20,000 overdose
`deaths. Source: CDC WONDER
`
`https://www.drugabuse.gov/related-topics/trends-statistics/overdose-death-rates
`
`7/11/2018
`
`ALKERMES EXHIBIT 2005
`Amneal Pharmaceuticals LLC v. Alkermes Pharma Ireland Limited
`IPR2018-00943
`
`Page 1 of 9
`
`
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`Page 1 of 9
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`Home » Related Topics » Trends & Statistics » Overdose Death Rates
`
`Overdose Death Rates
`
`Revised September 2017
`
`The U.S. government does not track death rates for every drug. However, the National
`Center for Health Statistics at the Centers for Disease Control and Prevention does collect
`information on many of the more commonly used drugs. The CDC also has a searchable
`database, called CDC Wonder.
`
`Drugs Involved in U.S. Overdose Deaths * - Among the more
`than 64,000 drug overdose deaths estimated in 2016, the
`sharpest increase occurred among deaths related to fentanyl and
`fentanyl analogs (synthetic opioids) with over 20,000 overdose
`deaths. Source: CDC WONDER
`
`https://www.drugabuse.gov/related-topics/trends-statistics/overdose-death-rates
`
`7/11/2018
`
`ALKERMES EXHIBIT 2005
`Amneal Pharmaceuticals LLC v. Alkermes Pharma Ireland Limited
`IPR2018-00943
`
`Page 1 of 9
`
`
`
`Overdose Death Rates | National Institute on Drug Abuse (NIDA)
`
`Page 2 of 9
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`Total U.S. Drug Deaths * - More than 64,000 Americans died
`from drug overdoses in 2016, including illicit drugs and
`prescription opioids--nearly double in a decade. Source: CDC
`WONDER
`
`* Provisional counts for 2016 are based on data available for analysis as of 8/2017. Counts
`through 2015 are based on final annual data.
`
`National Overdose Deaths—Number of Deaths Involving Cocaine,
`with and without opioids. The figure above is a bar chart showing
`the total number of U.S. overdose deaths involving cocaine from
`
`https://www.drugabuse.gov/related-topics/trends-statistics/overdose-death-rates
`
`7/11/2018
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`Page 2 of 9
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`Overdose Death Rates | National Institute on Drug Abuse (NIDA)
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`2002 to 2015, with the red line representing the number of
`cocaine deaths that also involved opioids, and the purple line
`representing cocaine deaths that did not involve opioids. These
`categories were equal in 2010. Since then, deaths involving both
`cocaine and opioids have more than doubled, while cocaine deaths
`not involving opioids have increased by only nine percent.
`
`National Overdose Deaths—Number of Deaths Involving Opioid
`Drugs. The figure above is a bar chart showing the total number of
`U.S. overdose deaths involving opioid drugs from 2002 to 2015.
`Included in this number are opioid analgesics, along with heroin
`and illicit synthetic opioids. The chart is overlayed by a line graph
`showing the number of deaths of females and males. From 2002
`to 2015 there was a 2.8-fold increase in the total number of
`deaths.
`
`https://www.drugabuse.gov/related-topics/trends-statistics/overdose-death-rates
`
`7/11/2018
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`Page 3 of 9
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`Overdose Death Rates | National Institute on Drug Abuse (NIDA)
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`National Overdose Deaths—Number of Deaths Involving
`Prescription Opioid Pain Relievers (excluding non-methadone
`synthetics). The figure above is a bar chart showing the total
`number of U.S. overdose deaths involving opioid pain relievers
`(excluding non-methadone synthetics) from 2002 to 2015. Non-
`methadone synthetics is a category dominated by illicit fentanyl,
`and has been excluded to more accurately reflect deaths from
`prescription opioids. The chart is overlayed by a line graph
`showing the number of deaths of females and males. From 2002
`to 2011 there was a 1.9-fold increase in the total number of
`deaths, but it has remained relatively stable since then.
`
`https://www.drugabuse.gov/related-topics/trends-statistics/overdose-death-rates
`
`7/11/2018
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`Page 4 of 9
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`Overdose Death Rates | National Institute on Drug Abuse (NIDA)
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`National Overdose Deaths—Number of Deaths Involving Heroin.
`The figure above is a bar chart showing the total number of U.S.
`overdose deaths involving heroin from 2002 to 2015. The chart is
`overlayed by a line graph showing the number of deaths of
`females and males. From 2002 to 2015 there was a 6.2-fold
`increase in the total number of deaths.
`
`National Overdose Deaths—Number of Deaths Involving Heroin
`and Non-Methadone Synthetics. The figure above is a bar chart
`showing the total number of U.S. overdose deaths involving heroin
`and non-methadone synthetics from 2002 to 2015. The latter
`category is dominated by illicit fentanyl overdose; when combined
`with heroin, these numbers capture illicit opioid deaths. The chart
`is overlayed by a line graph showing the number of deaths of
`females and males. From 2002 to 2015 there was a 5.9-fold
`increase in the total number of deaths.
`
`https://www.drugabuse.gov/related-topics/trends-statistics/overdose-death-rates
`
`7/11/2018
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`Page 5 of 9
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`Overdose Death Rates | National Institute on Drug Abuse (NIDA)
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`Page 6 of 9
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`National Overdose Deaths—Number of Deaths Involving
`Benzodiazepines. The figure above is a bar chart showing the total
`number of U.S. overdose deaths involving benzodiazepines from
`2002 to 2015. The chart is overlayed by a line graph showing the
`number of deaths of females and males. From 2002 to 2015 there
`was a 4.3-fold increase in the total number of deaths.
`
`National Overdose Deaths—Number of Deaths Involving Cocaine.
`The figure above is a bar chart showing the total number of U.S.
`overdose deaths involving cocaine from 2002 to 2015. The chart is
`overlayed by a line graph showing the number of deaths of
`
`https://www.drugabuse.gov/related-topics/trends-statistics/overdose-death-rates
`
`7/11/2018
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`Page 6 of 9
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`Overdose Death Rates | National Institute on Drug Abuse (NIDA)
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`females and males. From the lowest number in 2010 to 2015,
`there’s been a 1.6-fold increase in the total number of deaths.
`
`National Overdose Deaths—Number of Deaths Involving Cocaine,
`with and without opioids. The figure above is a bar chart showing
`the total number of U.S. overdose deaths involving cocaine from
`2002 to 2015, with the red line representing the number of
`cocaine deaths that also involved opioids, and the purple line
`representing cocaine deaths that did not involve opioids. These
`categories were equal in 2010. Since then, deaths involving both
`cocaine and opioids have more than doubled, while cocaine deaths
`not involving opioids have increased by only nine percent.
`
`https://www.drugabuse.gov/related-topics/trends-statistics/overdose-death-rates
`
`7/11/2018
`
`Page 7 of 9
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`
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`Overdose Death Rates | National Institute on Drug Abuse (NIDA)
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`Page 8 of 9
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`National Overdose Deaths—Number of Deaths Involving
`Benzodiazepines, with and without opioids. The benzodiazepines
`from 2002 to 2015, with the red line representing the number of
`benzodiazepine deaths that also involved opioids, and the purple
`line representing benzodiazepine deaths that did not involve
`opioids. From 2002-2015, benzodiazepine deaths involving opioids
`increased two fold more than those not involving opioids.
`
`The figures above are bar charts showing the number of U.S. overdose deaths involving all
`drugs, opioid drugs, opioid analgesics (excluding non-methadone synthetic, the category
`dominated by illicit fentanyl), heroin, heroin and non-methadone synthetics (to capture illicit
`opioids), benzodiazepines, or cocaine from 2002 to 2015. The charts are overlayed by line
`graphs showing the number of deaths by males and females. The highest rise was seen for
`deaths involving heroin, with a 6.2-fold increase from 2002 to 2015. The final two charts
`show the numbers of cocaine and benzodiazepine deaths that also involved an opioid;
`overdoses on these drug combinations have increased by nearly 2- and 5- fold respectively.
`These categories are not mutually exclusive and therefore cannot be summed.
`
`(cid:439) View/download supporting data document (XLS, 333KB)
`
`(cid:440) View/download (PPT, 1.13MB)
`
`This page was last updated September 2017
`
`https://www.drugabuse.gov/related-topics/trends-statistics/overdose-death-rates
`
`7/11/2018
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`Page 8 of 9
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`
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`Overdose Death Rates | National Institute on Drug Abuse (NIDA)
`
`Page 9 of 9
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`NIH...Turning Discovery Into Health®
`
`https://www.drugabuse.gov/related-topics/trends-statistics/overdose-death-rates
`
`7/11/2018
`
`Page 9 of 9
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