THE
`
`AMERICAN
`
`JOURNAL OF PSYCHIATRY
`
`UNDER “rut AW or
`
`THE AMERICAN PSYCHIATRIC ASSOCIATION
`
`EDITOR mums
`
`G. Alder alum. M. D.
`
`karma
`
`GLABEHCfi B. FAIRAR. M. D.
`
`2 Sway Place. Toronto. Chat
`
`555%”?! EMT”
`
`Charles Mt! Gamphefl. 14!. D.
`William Rush Danton.Jr..M. D.
`qui M. Kowma. ALI).
`Franklin (3. Ebaugh. M. 0.
`Thaophiie Raphael. M. D.
`Stanley Gohb. I“).
`
`Clarence 0. (Hum. u. 0.
`lizmy Suck Sullivan. H.9-
`Alvin T. ninth-ls, H. D.
`Anton J. RM. II. D.
`italic! I... Trudy”. I. Do
`Sililfll If. Hamilton. ll. D.
`
`FORMER ”"035
`
`link-I93!
`
`I).
`-
`John P. a...
`T. Danna lick. II. D.
`. H. D.
`_
`Mum fir!
`G. Milt flaunt. M D. Elem Iii-fl. II. D. May fl. “and. A. D.
`mmnmmm.
`
`VOLUME 94
`
`“The u" of the human mind it Ila than both lunch a! mainf—Gunsw
`
`mums
`
`19874”
`
`Page 1 of 20
`
`KVK-TECH EXHIBIT 1012
`
`Page 1 of 20
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`KVK-TECH EXHIBIT 1012
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`

`

`
`
`19: Both Gammon (puss
`QALTIH‘MHY. HD-
`I'. I. I.
`
`Page 2 of 20
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`Page 2 of 20
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`

`

`CONTENTS OF VQLUME 94
`
`
`
`1mm. my.
`
`In»
`
`.9
`
`9'
`
`I. Wml. Am; Mm ll Putnam. C. Huh
`Can-M ....................................................
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`A Hm m: m qunv PWA'II at him Um“ I: Hm».
`mm Walm HHMIMMa-dlflulmln
`Tm: Enter or Bums: 5mm w Clint)! m
`Mum. Sum. Pun-cw 6‘. Sch». 1!. C. Helium-I3 C. 8.
`Tu» and .4. 113mm .......................................
`mum at Cam In: hare-um Lam“ M;
`Bradley ..................................................... n
`51!. Yum 21mm Imu NW Tm In W.
`HeroldflPQEI-Incnll’mtm................... y
`7. Hrmm mun Pmm. Warm-T. Mud“
`
`I
`
`'5
`
`I9
`
`17
`
`5mm on 1W 1W Firm
`Tn: Psmmmc HAM-mums an ”mm m 1
`KW and.mm P. mun........................... I;
`Tum ..
`Uzi: or 11mm III III:Wu
`
`Bum Jim W................................. m
`Rmcmflmml'mmnm Rm Yum 3mm
`3mm him .11. Run ................................... m
`E!” mm m Emma: 1mm in m
`puma. 8m KW. um Hmmmnd
`
`mm Imam Tmm w mm 1%
`Wm.xm mmmbmmlml.
`3W ............................................... I”
`mm um um Bumvm 3mm MW or
`I’m. W H. Yaw and
`L. Numb ............................ . .................... Ifi
`Tummumfirmmewmm
`m M Chub ................................... Ir:
`Tmm at human Sm Hm 1. Iain............... In
`Tmfimuumukummmm
`Tum Hm Hum D. Em CW and
`Huh: 4. Rubin................................... . ....... 1.8.3
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`Page 3 of 20
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`

`iv
`
`cox‘mms
`
`so. COMMEXT:
`War Prophylaxis.—Psychiatry at the First Internalimal Com
`fat-once on Fever Therapy ..................................... #38
`:1. News AND Notes:
`Meeting of the American Psychiatric Association—Calendar of
`Psychiatric Meetings.”The Amerim College of Physician 1953
`Meeting.”Residmocs in Neuronsychiau'y.mfiufllu of Hm
`Heredity. Londun"American Associatisa on Mental Deficiency.--
`Meeting" of the Academy of Physical Medicine .................. 222
`:3. Boos szmws:
`Administrative Psychiatry. W illionu J. Bryan ................... 339
`Twins: A Shady of Heredity and Enviralment. H. H. New,
`Frame N. Freeman and Kori J. Hoisting" ..................... 230
`Practical Examination of Personality and Behavior Disorders.
`Kenneth E. rifle! cold Eduard A. Stacker ................... 2.3:
`Psychological Studies of Hum Variability. Walter R. Kiln,
`Editor ................................................... 231
`Prostitution: An Investigation of Its Cameo, Ele with Ron
`gal-d to Heredizuy Factors.1‘ooe Km} .................... 23.:
`Hints to Probatiooers in Hamil Hospitals. Rid-en! Eager”
`.134
`Prisons and Beymd. Sanford Bole: ............................ 335
`Esau star la Schizoohuie. Jacques Detour-d .................... 215
`The Mwnlly III"III mike. A History of Theix Cue end Trut-
`meoi from Colonial Times. Albert Drum); ................... 339
`
`13.11! Mum:
`S. A. Kinnie'r Wilma. G. M. C................................ m
`
`Semen. logo.
`
`1. Tue Common Aoume Rumor. Will-”on 6. Leona: ........... as:
`
`a. Fmsosxs in Room Diocese. To: Use or Orphan Moms.
`Earl D. am and From-i; J. 31mm: ......................... .163
`a... 3. To: Sm“. To: lxnmnuu. no H15 Home; mm. W.
`Lloyd Warner ............................................... 275
`4. Exmws Rem-non Turns to Boom ism. (Damion
`Fm) B. H. Snow”... .......... . ..................... is
`s. Tue Cm or Exm‘umm. Funnies mm Mum Coniwms.
`Dom C. With“ ............................................. 29g
`6. A Review or On; Huum no anFwe Cues or Am
`
`Elm-Arm Seven YEAH. Leslie 8. Hum............ go;
`1AM [nuance or Deuenm Pmcmca. NW C. Paternal... .goo
`8 Emma Rumsmuoss In (Room 1W3. In» C
`
`WW ................................................. an
`9. 5m Psvonmmc Am or Bum Comm in P. Km” :17
`lo. Lumen? mu: rue Moos. Cori E. Tron .....................
`339
`ll. Nunmo Eoucxnon. Hey Kennedy ............................. 345
`
`
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`Page 4 of 20
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`(“OHTEHTS
`
`V
`
`12. Tu; Inflamft Tmrmt or Senizorumu In“ a an
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`14. Pm" Cam In San». Rmmcnm Sm“ W. Hut-Ill m
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`Wynn-m Tm. Nmu C. Kerb-n w H. flu
`Hacks: ................................................... m
`16. Tu mmmw Fawn—Pm ”A Bar. Silva Tin-thou an
`17. Putnam or 5mm:
`PM” a! Himety-Third Am! m d 11!”: Autism
`Psychiatric AW ...................................... 43;
`18. W Senmm: m or we Num‘l'nm ”WM.
`Km“ w Tn: Autumn Psvcuum Amun- cu Com
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`um Rm ............................................. a;
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`”Nunavut...” .......................................... m
`
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`

`vi
`
`('ON TE N TS
`
`PUML Psvcuosnn mo Tum Snoru..r.. Louis 1. Romania and
`
`Justin M. Hope .............................................. 537
`Unmann- or FAHILY Cut In New You Sure. Rings 6.
`Hubbtfl ..................................................... 55:
`
`Mani-u. Rue-mus nun Tam MANAGIIIIIIT iii Psi-luvs wmi
`CAIDIAC DISEASE. P. H. Drm. In. and Joint: H. Wei! ........ 96:
`Ton Heisman or claims Recemuo Bantam". Charla
`
`Bradley ..................................................... 377
`Tm: Em or Emu-mm: Svunm on 18!. [amnion-sits. Sculls
`or Cnmu. Hauling Molitdi and AW K. Eula ........... 97
`A Psvcmnfluc STUDY or RICIDWIS'I’I. Charles B. flea-um ...... 591
`MENTAL Cannons Fawwmo flu Remove; or use RIGHT le- ...\
`uni. Hkfllfl'flm Ion Bum “fusion. Stuart N. Rm .......... 605
`Harem on lnmmwcc mu Foul. LESIONS iii-inns use
`
`(2cm Pen or 1"!!! Lim- (Immune Hfilflsfllm Leland B.( ”Ni
`
`Alford ......................................................
`Somme AllY‘l'Al. AS A Summon iron Tune Feminism. William H.
`Foley and Vincent P. Ramona ................. . ..... . ....... 639
`Panes“ Arm Huston. David M. Levy ....................... 643
`Conn Assn-sis as n Tmnutqvc iii to: lumonnous or
`Memes. uneasiness. Maroon: W. Gmrd ................... 65;
`(2mm Psvcumnv. 1m: 5'. Pine: ............................. 665
`Soul: Tunes-now: Putnam Amman no PSYCflIn‘fllC Woes:
`
`mm Coma. Frederick H. Allen ........................... 67:
`Ali Euwnflox or can Tsunam- or PM Cums: as
`
`Dmmnco IV A me-UP Scum. Ham W. Pam-- and
`[infinite R. Klein ........................................... 631
`
`PM Can-blur Gunman Ur. Ln Kai-m ...................
`
`69ml
`
`933
`
`II).
`
`II.
`
`13.
`
`i3.
`:4.
`
`IS.
`
`. MENTAL Cannons
`
`luaunmo Mfiuln ”I n Psmr urn-Ii E\
`
`Siam Out. Ancient. Bum Ham and S. H. Kraut: .....
`Cousin”:
`The Problem of the Sea: cam ............................
`News sun Nam:
`
`”J
`
`Graduate Course in Psychietric Nursing.--Soudinrn mm
`[lamination-m Psydiiettic Associetimw—Dr. 1w Gives
`Terry Lectures at Yeltmniphmhs of Iii: AM Bill!!! of
`Psychiatry uni Neurology. Inna—Dr. Joseph E. Build! ID DWI
`Michigan Sm: Hospital Commission.---Second Insunetionni Con-
`em on Mme! HygienemAmman Public Ham: Ail-mission
`Matting. immD'r. Watching Appointed SW of Pil-
`grim Shite Hospital—Dr. Travis Apooinied We; oi
`Willard Sm Rupiah—Dr. Ziegler Emma Associelc Radial
`Dim oI Nilmukoe SenitedMW-Sociel Hmiene Dem-«Md:-
`visory Board for undies] Specialties end Gm Medical
`Edmtim.—-Sociometry. A Journal oi Inter—Pam Relational."-
`First International Comm: on Guild Psychiury.isychietfl:
`Journal of the Biology and Pathology of buns-personal Rchtions.. 72in
`
`
`
`Page 6 of 20
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`Page 6 of 20
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`

`

`manure.
`
`vii
`
`no. Bushmws:
`WWHMTM RHMMIK.
`Walther
`.................................................. 737
`Therutd‘I‘heWuthn; cmvmmm
`vatvwm: WiflkuPetrurI ........................... m
`FmchdHuflhWAlluu-dfimdfm
`CueinhmfiWflMflPe-fleehm...... 7:3
`WWMWMWLH
`
`FMMMdMWMflMMI
`The Mutant Fm at
`the Pram! m m H.
`WWWWM Mfimmu I":
`Bridfler ..................................................
`TheflmfiimMfimme G W
`Scan ................................................... 3‘
`mwmmwmhm 3mm!
`Terr-garnet .............................................. 74.
`LIMMPWRIIWWHM
`Mm ......... . ......................................... 753
`
`V. mm and Alan: Cm:.........
`
`........... m
`
`JRNL’AIV. 1938.
`
`I. LuumSeumar [1:ch 11!. Lemming-unfit. K.
`HMH . .............................................. 759
`2 CmmWAmn-mtmumm
`mam Men-me-............................. In
`3. Wnrmtummhmwmhrmv
`Drum MW.................................... 3m
`4. Inwemqmmhmnnummrwa
`3mm ................................................. has
`5. WMHWFHWHWVHIM
`MHMHJWMIHC‘NM............... I.”
`6. .amHmfimm NmLM........ m
`7. Mum Dem m hum 1m; Page........................ m
`I. Haitian“... fixatimuuuu ...................... any
`9. anmm err m hm er WA.
`Mummmmmwm Hum........ in
`to. Vmumt (2 51mm m We. Hm mm. S. W
`Wmhedpmrl.flm................................. I”
`
`Page 7 of 20
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`Page 7 of 20
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`

`

`viii
`
`CONTENTS
`
`ll. Amuxsls or SI'DKEN LASGL’AGE or PA"? x15 wrm Am“ Dua-
`
`m Stanley NW and Vera G. Mather ................... 9'»!
`12. A Renew or rm: Wan: ox Exm-Szxsnn Pam-nos. 0an L.
`Wolfl:
`...................................................... ya )
`13. COHKEETS on 1):. Wme’s Renew. I. B. Rbiur ................. _ 7
`:4. Nsvwsns AND Neuwrsvcnoszs. Abraham ”germ .............. fit
`15. Count“:
`the
`in Massachmelts.—-Anmnl Meeting of
`Continued ”meet
`American Public Huith Association ........................... 905
`:6. News um Nuns:
`
`American Orthopsychiatric Association Annual Meeting—Rer-
`pnn of Nomimting Committee—Jim American Physkilns' Art
`Association.«—Dipla.mates of the American Bond 0! Psychiatry
`and Neurology. Inn-"Jasmin (Salim—Harlem Valley Sun:
`Hospital.me Course at the Menuhin:- Oink—California’s
`Fire—Year Study Program for Graduate: in Medicine ........... 991
`:7. Boon: Rev-mars:
`Methods of Treatment. Logan Cicada-rug ...................... 997
`The Hm Mind. Karl A. Mann-yer ........................ yyli
`Die Psychische Impotenz {In Manna. Edmund Brrglrr .......... lam
`Sixtwaini Annual Report of Statistics of CW and Other 0(-
`{ennes for the Year Ending September an. 3935 ................ rm;
`A Text-Book 01 Mental Defieimey. A. V. Tulsa“ ............. rm
`Biological Time. P. Lemmy: drl Naiy ........................ [M
`Our Children in a Gunning World: An Outline 0! Practical Gui-
`dance. Erwin Wrxbrrg and Henry E. Friurb ................. {m
`Annualio deila Pmtificia Academia Dells 5cm ............... 1M
`:8. hr Managua:
`Alfred Adler. 1870-1937. Otya Knopf .......................... nnny
`
`1
`
`“RICH. '9”.
`
`1. Km: Camus Muses or mem Pmnus mm Tnm
`Commences. Leo Knmr ................................. mu
`2. Tu; Exmmexuu. qumm um um Plan-ml or Mum. ms.
`_ mm H. S. LEM“.................. . ..... . ................ 1035
`3. Ismfixmtmmn: “rue Cancun um Tum Canaan. Use.
`R. H. Collier and Minna Each ............................... 1m
`4. Tue Armmu. or lama; an» Farm Fae-mes Am
`Cm Dannie 13 Cum. Bram Cram: and 51mm
`Lard ................................................. . . . . . . 1m
`5. Tn: Oran Sun; or Hmummmus. 1mm Lung ........... rain
`6. A knew or “me Rustin-I mu me Eumum or M
`Tamer It: ran Tmruexr or Nemrmms Ill rite PM
`Sun Bowen. um F. Boyd, W. K. Simian-Thom, S. F.
`mum and W. H. Kappa ................................... um
`
`Page 8 of 20
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`Page 8 of 20
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`

`

`mans”
`
`ix
`
`7. Hummus! Fun at Puum Pmcflmnms Am: or tn
`Cm Cm: Wm was Mm. Wm.
`am I. Am ......................................... Ins
`8. A Confined“: Cass-mm or Cums Hum». muss.
`Karl H. Rm ............................................ n4!
`9. 51-511mm Cantu-amass man "in mam; Hm: Sww
`wumtumsflnml msnmummnm WM.
`Coki- did M 5. Farm ................................. I153
`no. Tm Damn-mm me or nu Manta Tm. 1m 0.
`Min-flu and Emilia G. amt; ............................ no:
`1:. Sam. Curacao. an Hum m or m Bum
`Baum-1m lmp‘ Hugh's. W A. Samba and KM
`5. Jpn! ................................................... "ZEL- 3
`:2. Wm harem Hindu H. AMI".................. nip
`1;. Munnmls‘t‘nu Emmwmrqufl-rm
`um 1mm at Emmv m CW. Hm F. HM
`and Hour 6% ........................................... was
`14. Sam Dan or "II Pflcmc I‘m at In: A» m m
`Pnunm. 1,. Hum ...................................... m5
`:5. chnum Hum" an Mm u: Cm Har-
`wfl H. Sum ............................................. 1m
`
`
`
`AWmWWm Dam—“FM...... tm
`l9. Emmi:
`mumummsmnm WM
`msmmrw ............................... m
`memflam'sWMN
`
`
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`MRWMMMWWMTM ......... nm
`WhchflnltWCHm ........................... 1354
`[at ”mm:
`Hmflmlmcmwwfiulnm........ um
`
`m.
`
`
`
`Page 9 of 20
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`Page 9 of 20
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`

`

`CONTENTS
`
`MAY. 1938.
`
`I.
`
`.-l. Mat-
`Pants-.15. AN ANALYSIS or 51! Tatum Casts. Reba-rt
`thews, Robrfi .S'. Boakhmrlmr and William H. 1:10? ............. 1259
`
`Amvsnram nun 11's Linn-s. Eagra Kali: ...................... 1277
`Custom-unaware (Susanna-nous Iva: mustn't-1M. DIAGIIOSIS
`
`Bus-wax Jeanna: Paums an Oran Fouls or EHCEPKAU‘flI.
`A. Fma, S. E. Barrera and H. 5'. Guam .................... 1291
`Ans-mac: a: "On: Human» Yuma arr Nox-Rummt.” E. Mao
`
`ringer and Mryrr A. AMI]? .................................. 137’
`Tu: Puaauncozancm. "SHOCK" Tmmwr a: Cams“: Scum)-
`PHREKIA. I. Murray Ram and William 8. Clint ............. am
`()nsuvamms u: rm: vauczmc Tmmnrr or 55 Can: or
`Scnlzm'unmn. Dan}! Rm" ............................. um
`. Tmmwr or Parmesan wmn Pmuummxflmtm. H. M.
`
`'J!
`
`‘I
`
`NmPnydIiau-ic 11»!th of the Hatfield WWW
`
`Gamma, E. F. Dombrmnfl. J. V. Edith. A. P. Bay. C. I.
`MrCo'fiy and J. H’tiubrrg ..................................... I”
`81.0!» (25:11:an Canaan; Occvmnm Ia ma Tun-natal? or Pvt-
`
`tummy: Hutu. [Manama II 11mm Comumm. S.
`
`Mower, H. 0. Wilt-1. C. M. Marbtry, B. Stardéln and M. L.
`Fc'rlm-
`...................................................... 1355
`Rum; Van-m: m m: Tsunami: or Eran“. [More Fish!-
`
`man, Alex. J. Aririf and Malaria A. Srbilhr .................... 1363
`THE Us: or Ismnuovs Hartman: Bum “I Sums Coleman!»
`“35. Ludo Kajdl' and Chan-la V. Tudor........................ :fi
`Sunmcan. Comaurmxs mu m: Kantian. Harman: Swan: at
`
`m: Emma Hanna Dram a: Mum II. Put-nous
`m rug Eastman Hum-n Dunner 8mm 1!. CM and Ruth
`B. Firm ............................................... 13;"
`TH: Mme Huntsman or Our-natal: an Cinnamon. Paul
`Schiller
`.................................................... law
`Tm: Parmnuaamc Cumming: or Pmmw Tun. Em
`u! E. Hadley ................................................ “l7
`Psrcnmaaamc Cuumauflmrs to ma Calm w Hum
`Tum. N. Lame! Blimm .................................... ml
`Tn: Pau‘uanmr or 11!: Susan Wain-v RM: and 3m
`Km .................................................... I“!
`Pm Gun» Simulations m Mauro-Datum": Pamufi. Edw
`de. SWMLIIME. Hm ......................... [459
`(Scum:
`Tribune to Dr. Jelli.flc.-—'fhe Syndrm o! I“ in the Aim m4.”
`Haws am Non-n:
`Tmty-Fiith Mniwrnary of the Henry Phipps Farm
`Clinic.—Teuth Imtimnl um (2mm hr PM
`—Cooperativ: AW human-.11 Weflcyan UniImity Md the
`
`_
`
`10.
`
`13.
`
`13.
`
`Mr
`
`15.
`
`:7.
`
`:8»
`
`Page 10 of 20
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`Page 10 of 20
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`

`

`COHWHTS
`
`Xi
`
`
`.
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`..
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`
`a]. Annulum ................................................ W
`
`
`
`Page 1 1 of 20
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`Page 11 of 20
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`

`

`THE
`
`BEHAVIOR
`
`CHILDREN
`OF
`BENZEDRINE.*
`
`RECEIVING
`
`BY
`
`CHARLES
`
`BRADLEY,
`
`M. D.,
`
`EAST
`
`PROVIDENcE,
`
`R.
`
`I.
`
`A
`
`in
`
`of
`
`and
`of
`are
`in
`certain
`undertaken
`
`institution
`
`are
`
`of
`
`the
`
`child
`under
`are
`
`to
`conditions
`controlled
`laboratory
`situ-
`of
`a
`patients
`of
`normal
`years
`of
`age
`12
`Since
`chil-
`such
`setting
`de-
`been
`has
`of
`com-
`outside
`sports,
`etc.
`Although
`sort
`daily
`activity,
`his
`patients
`
`of
`records
`general,
`
`be-
`
`of
`the
`
`benzyl
`has
`
`methyl
`recently
`stimulant
`are
`now
`of
`reports
`psychologi-
`and
`other
`appears
`to have
`studied
`Since
`psychological
`the
`have
`any
`sort
`appears
`to
`since
`some
`of
`the
`changes
`a
`type
`which
`might
`theo-
`behavior
`problem
`chil-
`at
`the
`Emma
`Pendleton
`
`admirably
`
`adapted
`
`the
`
`an
`
`(beta-aminopropylbenzene;
`of benzedrine
`use
`The
`nervous
`system
`as
`a
`central
`carbinamine)
`considerable
`comment.
`number
`aroused
`describing
`effect
`the mood
`upon
`its
`available
`of
`but
`no
`one
`so far
`adults,’T
`cal
`reactions
`of
`children.
`the
`behavior
`upon
`its
`effect
`therapy
`of
`children
`to
`drug
`response
`a generally
`neglected
`subject,8
`been
`produced
`by
`benzedrine
`adults
`retically
`prove
`of
`clinical
`value
`dren,
`present
`studies
`were
`Bradley
`Home.
`this
`of
`The
`facilities
`children’s
`of
`observation
`under
`behavior
`distractions
`artificial
`the
`introducing
`without
`with
`resident
`only
`deals
`The
`hospital
`ation.
`children
`under
`being
`majority
`the
`intelligence,
`and
`neurological
`presenting
`behavior
`disorders.
`treatment
`the
`hospital
`prolonged
`dren
`require
`of
`the
`desirable
`features
`signed
`to provide
`most
`scouting
`activities,
`munity,
`including
`school,
`with
`a very
`natural
`each
`busies
`himself
`observation,
`and
`careful
`is
`he
`constant
`a matter
`routine.
`In
`havior
`kept
`as
`are
`this
`close
`scrutiny.
`of
`unaware
`quite
`effect
`of
`benzedrine
`To
`observe
`dren,
`already
`resident
`patients,
`30
`a
`variety
`of
`behavior
`disorders,
`child
`in
`this
`group
`already
`
`the
`
`had
`
`the
`upon
`the
`hospital,
`for
`selected
`under
`observation
`
`behavior
`suffering
`study.
`for
`
`in
`were
`been
`
`of
`
`at
`
`chil-
`from
`Every
`least
`
`Pendleton
`
`the Emma
`*
`of
`this
`Portions
`study
`in Dementia
`for Research
`Northern
`Masonic
`Jurisdiction,
`
`were
`
`Home.
`Bradley
`possible
`made
`founded
`Pnecox
`U. S. A.
`
`by a grant
`from
`by
`the
`Supreme
`
`Committee
`the
`Council,
`330,
`
`Page 12 of 20
`
`(cid:1)
`

`

`578
`
`EFFECTS
`
`OF
`
`BENZEDRINE
`
`ON
`
`BEHAVIOR
`
`[Nov.
`
`Twenty-one
`a month.
`studied,
`were
`girls
`nine
`and
`to the
`admissions
`all
`for
`noted
`approximating
`of
`sexes
`one
`girl
`boys
`and
`two
`years,
`from
`ranged
`The
`ages
`their
`13th
`disorders
`behavior
`children’s
`birthday.
`passed
`but
`varied
`hospitalization,
`have
`severe
`enough
`to
`disabilities,
`specific
`educational
`ranged
`siderably.
`They
`schizoid
`behavior,
`to the
`retiring
`secondarily
`disturbed
`aggressive,
`egocentric
`epileptic
`child
`on
`the
`one
`hand
`and
`intelligence
`was
`in
`general
`within
`the
`other.
`The
`patients’
`range.
`the
`so-called
`“normal”
`and
`observation
`addition
`to
`routine
`In
`child
`by ward
`nurses
`and
`teachers,
`each
`for
`a period
`of
`three
`weeks
`a special
`by
`this
`nurse’s
`customary
`duties
`had
`already
`ciation
`with
`all
`of
`children,
`she was
`his
`her
`each
`patient
`without
`recognition
`of
`second
`time.
`During
`the
`week
`of
`observation
`of
`benzedrine
`10 was
`administered
`to
`each
`Later
`the
`of
`his
`behavior
`during
`this
`with
`those
`week
`prior
`the
`week
`taken
`as
`periods
`for
`particular
`
`ratio
`this
`hospital.
`having
`were
`con-
`with
`child
`on
`
`quite
`
`of
`
`recording
`was
`personally
`psychiatric
`nurse.
`involved
`daily
`able
`to
`observe
`special
`function
`a daily
`morning
`patient
`upon
`week
`were
`following,
`child.
`
`behavior
`observed
`Because
`close
`asso-
`carefully
`at
`this
`dose
`arising.
`compared
`which
`were
`
`boys
`that
`5 to
`
`14
`The
`warranted
`from
`school
`the
`
`the
`
`records
`of
`the
`control
`
`and
`this
`
`SCHOOL
`
`PERFORMANCE.
`
`in
`the
`
`the
`
`most
`therapy
`
`all
`
`change
`striking
`Possibly
`in
`occurred
`benzedrine
`of
`children
`Fourteen
`these
`patients.
`of
`reporting
`teachers,
`fashion.
`Different
`accomplishment,
`in
`age
`school
`and
`material
`was
`interest
`in school
`to
`accomplish
`a
`definite
`“drive”
`often
`to
`spend
`school
`period,
`and
`work.
`Speed
`of
`comprehension
`cases.
`increased
`in most
`Insight
`erally
`present,
`though
`few of
`cation
`they
`received
`earlier
`had
`noted
`in
`school
`subjects.
`given
`and
`benzedrine
`was
`discontinued.
`
`noted
`
`the
`
`behavior
`school
`responded
`on
`these
`agreed
`that
`immediately.
`as much
`as
`extra
`time
`and
`accuracy
`into
`school
`children
`day.
`in the
`It
`appeared
`disappeared
`
`on
`
`during
`activities
`in
`patients,
`a great
`There
`possible
`completing
`of
`performance
`improvement
`attributed
`The
`promptly
`the
`
`of
`
`the
`
`week
`the
`of many
`spectacular
`who
`varied
`increase
`appeared
`during
`additional
`were
`gen-
`was
`to the medi-
`it
`improvement
`was
`the
`day
`first
`day
`it was
`
`a
`
`first
`
`Page 13 of 20
`
`

`

`1937]
`
`CHARLES
`
`BRADLEY
`
`579
`
`children
`were
`There
`15
`was
`who
`child
`one
`some
`improvement,
`personal
`characteristics.
`performance,
`although
`altered.
`Two
`children
`elsewhere.
`
`and
`show
`in
`their
`school
`distinctly
`school
`
`or
`
`show
`not
`did
`who
`age.
`school
`not
`of
`other
`accompanying
`others
`Five
`behavior
`their
`showed
`no
`
`so
`Of
`
`striking
`the
`15,
`temporary
`showed
`in
`other
`response
`
`a change,
`did
`eight
`changes
`change
`no
`respects
`the
`
`in
`was
`in
`
`drug
`
`to
`
`EMOTIONAL
`
`RESPONSE.
`
`be
`
`that
`an
`
`30
`
`responses
`emotional
`discussing
`In
`in mind
`kept
`it must
`essentially
`was
`disorder
`the
`conduct
`children
`in many
`of
`these
`the
`Fifteen
`of
`of
`emotional
`maladjustment.
`external
`symptom
`subdued
`distinctly
`benzedrine
`by
`becoming
`to
`children
`responded
`an
`was
`this
`cases
`all
`responses.
`Clinically
`in
`in
`their
`emotional
`accom-
`it was
`the
`social
`viewpoint.
`In many
`improvement
`from
`the
`of well-being;
`but
`superficially
`panied
`sense
`by
`appearance
`become
`diminished.
`whose
`mood
`swings
`had
`was
`a
`child
`some
`children
`who
`expressed
`their
`In
`were
`irrita-
`noisy,
`aggressive,
`domineering
`behavior.
`by
`bility
`activities
`influence
`of
`the
`more
`the
`Such
`under
`drug
`became
`placid
`and
`Coincidentally,
`they
`seemed
`to
`become
`more
`in-
`terested
`surroundings.
`Such
`changes,
`however,
`no means
`paralleled
`improved
`performance
`noted
`as
`only
`seven
`were
`both
`groups.
`
`that
`this
`
`a
`of
`group
`in group
`children
`easy-going.
`in their
`the
`children
`
`had
`
`school
`common
`
`to
`
`by
`above
`
`remaining
`the
`noted
`were
`responses
`emotional
`of
`them
`Seven
`of
`of well-
`sense
`of
`only
`evidence
`gave
`questioning
`Although
`euphoria.
`of mild
`to
`the
`point
`studiously
`was
`feelings
`subjective
`their
`to
`in
`regard
`joy
`have
`“I
`as,
`such
`remarks
`spontaneous
`instances,
`enough
`seem to do things
`can’t
`fine
`and
`feel
`I
`fast
`I
`before
`and
`“I
`start
`to make
`my
`peppy,”
`feel
`bed
`of
`All
`“I
`feel
`fine,”
`seemed
`significant.
`is done,”
`and
`them,
`showed
`a widening
`of
`interest
`in things
`around
`at
`least,
`a diminished
`tendency
`to
`preoccupied
`
`“
`
`in
`
`a
`
`be
`
`ing
`tions
`
`patients
`that
`they
`more
`easily
`
`to cry much
`observed
`were
`received
`benzedrine,
`as
`aroused.
`Two
`others
`
`more
`though
`were
`noted
`
`dur-
`easily
`their
`emo-
`to wear
`
`A variety
`children.
`15
`being,
`even
`the
`children
`all
`avoided
`in
`in my
`stomach,”
`today,”
`“I
`know
`it
`it,
`patients
`these
`and
`superficially
`with
`themselves.
`Three
`other
`the week
`were
`
`Page 14 of 20
`
`

`

`580
`
`EFFECTS
`
`OF BENZEDRINE
`
`ON
`
`BEHAVIOR
`
`[Nov.
`
`to
`
`worried
`one
`child
`ing more
`As was
`changes
`appeared
`
`expressions
`of
`the
`hyperactive,
`the
`case
`appeared
`as
`soon
`
`quite
`
`entire
`
`foreign
`responded
`30
`aggressive
`alterations
`with
`the
`promptly
`on
`as
`the
`drug
`was
`
`appearance.
`usual
`their
`the medication
`to
`irritable.
`and
`school
`in
`first
`day
`stopped.
`
`Only
`becom-
`
`by
`
`all
`and
`
`these
`dis-
`
`performance,
`of
`treatment
`
`OTHER
`
`PSYCHOLOGICAL
`
`CHANGES.
`
`is
`action
`changes
`difficult
`general
`In
`
`of
`
`may
`
`be-
`about
`in motor
`became
`talked
`with
`One
`
`boys
`walked,
`interfere
`the ward.
`
`to
`
`ex-
`be
`naturally
`a stimulant
`of
`that
`whose
`A drug
`how-
`children,
`In
`in motor
`activity.
`produce
`pected
`to
`apart
`activity
`to measure
`motor
`ever,
`is extremely
`it
`se
`(cid:1)er
`and
`his mood
`by
`behavior
`as
`shown
`from
`individual’s
`the
`decrease
`of motor
`our
`patients
`some
`his
`intellectual
`activity.
`became
`emotionally
`the
`children
`who
`in
`activity
`was
`usually
`noted
`elation
`possibly
`responded
`with
`who
`subdued.
`A few
`those
`daily
`routine
`in
`particularly
`their
`came
`little
`more
`active,
`a
`increase
`an
`showed
`patients
`the
`hospital.
`Only
`three
`three
`These
`changes.
`other
`activity
`not
`explained
`by
`to the
`point
`agitation,
`of
`than
`rather
`ran
`about
`active
`as
`were
`so stimulated
`more
`rapidly,
`and
`in general
`on
`and
`work
`in
`school
`the
`efficiency
`of
`their
`daily
`was
`the
`defiant.
`and
`became
`noisy
`of
`these
`child
`who
`expres-
`a worried
`mentioned
`as having
`Another
`boy,
`previously
`motor
`activity
`in-
`among
`the
`three
`whose
`and
`also
`included
`sion,
`was
`of
`agitation
`and
`worry,
`afraid
`to
`creased,
`expressed
`feeling
`times
`run
`away,
`was
`at
`fearful
`of
`go
`out
`for
`fear
`he might
`and
`such
`before.
`death.
`He
`had
`not manifested
`symptoms
`It will
`be noted
`that
`comparatively
`little mention
`under
`the patients’
`subjective
`feelings
`the
`influence
`of
`Personal
`questioning
`any
`child
`deliberately
`of
`was
`not
`to
`influence
`his
`behavior
`artificially
`through
`indicating
`that
`he was
`the
`object
`of
`particular
`of
`subjective
`responses
`are
`therefore
`limited
`taneous
`remarks
`which
`the
`children
`made,
`been mentioned.
`
`been made
`has
`of benzedrine.
`avoided
`so
`suggestion
`or
`attention.
`Records
`to the
`occasional
`spon-
`and
`which
`have
`already
`
`as
`by
`
`PHYSIOLOGICAL
`
`OBSERVATIONS.
`
`In
`changes
`
`view
`
`of
`
`1,
`
`6,
`
`11,
`
`observations
`the
`12 may
`follow
`
`others
`of
`benzedrine
`
`that
`therapy,
`
`certain
`such
`
`physiological
`routine
`
`cx-
`
`Page 15 of 20
`
`

`

`1937]
`
`CHARLES
`
`BRADLEY
`
`581
`
`not
`as would
`aminations
`these
`out
`during
`studies.
`given
`blood
`pressure
`was
`day
`on
`about
`during
`each
`in the
`erythrocyte
`cant
`change
`treatment.
`of
`the week’s
`of
`the
`enced.
`In
`six
`turbed,
`as
`evidenced
`the
`first
`night
`or
`for
`four
`nights.
`were
`morning
`meal
`of
`the
`experiment.
`present
`was
`uniformly
`distress,
`persisting
`Agitation
`and
`in adults,
`were
`
`30
`by
`
`for
`irritability,
`observed
`
`Body
`children
`a
`delay
`One
`patient
`two.
`of
`appetite
`Loss
`observed
`in
`Intolerance
`expressed
`an
`hour
`said
`in but
`
`carried
`were
`behavior
`influence
`artificially
`were
`which
`benzedrine
`doses
`of
`On
`the
`inconstantly
`but
`rise
`moderately
`noted
`to
`no
`was
`children.
`There
`the
`signifi-
`half
`as
`a result
`level
`or
`hemoglobin
`count
`appreciably
`influ-
`weight
`was
`not
`was
`dis-
`mildly
`nocturnal
`sleep
`falling
`asleep
`for
`time
`the
`of
`remained
`awake
`to
`late
`hour
`a
`the
`and
`nausea
`at
`the
`time
`few
`of
`the
`children
`start
`the
`at
`the
`of
`conventional
`when
`dose
`by malaise,
`nausea
`epigastric
`two,
`and
`usually
`by
`rest.
`be
`characteristic
`overdosage
`child.
`
`in
`
`a
`
`or
`to
`one
`
`of
`
`and
`relieved
`of
`
`DURATION
`
`OF
`
`EFFECT.
`
`were
`
`noted
`after
`
`to
`oral
`height
`
`to
`
`30
`changes
`with
`
`Psychological
`children
`havior
`hours,
`Occasional
`dose
`suggested
`more
`persistent.
`first
`day
`of
`and
`disappeared
`
`effects
`45 minutes
`their
`were
`at
`gradual
`disappearance
`sleep
`disturbances
`that
`in
`a
`In
`all
`administration,
`permanently
`
`over
`or more
`i6
`individuals
`few
`the
`instances
`continued
`as
`soon
`
`in
`
`of
`
`on
`
`the
`the majority
`appear
`Be-
`of
`the
`drug.
`ingestion
`third
`second
`and
`the
`during
`hours.
`of
`6 to
`a period
`12
`after
`the morning
`hours
`the
`stimulating
`effect
`was
`effects
`appeared
`the
`throughout
`week
`the
`drug
`was
`discontinued.
`
`full
`daily
`the
`
`as
`
`DOSAGE.
`
`received
`study
`this
`of
`objects
`the
`were
`who
`children
`The
`30
`It was
`arising.
`upon
`sulfate
`benzedrine
`of
`morning
`doses
`single
`on
`the
`basis
`to
`doses
`trial
`increasing
`giving
`gradually
`of
`found,
`amount
`generally
`a satisfactory
`20 mg. was
`that
`the
`children,
`few of
`physiological
`behavior
`without
`undesirable
`in
`to
`produce
`changes
`children
`studied
`were
`then
`the
`a trial
`given
`consequences.
`All
`but
`20 mg.,
`in
`gastrointestinal
`instances
`this
`resulted
`eight
`of
`in,
`to
`color
`child’s
`reactions.
`These
`distress
`sufficient
`all
`as
`children
`were
`therefore
`given
`daily
`during
`
`the
`10 mg.
`
`their
`
`dose
`
`a
`
`dose
`
`eight
`the
`
`Page 16 of 20
`
`

`

`582
`
`EFFECTS
`
`OF
`
`BENZEDRINE
`
`ON
`
`BEHAVIOR
`
`[Nov.
`
`of
`Two
`week.
`that
`suggesting
`cally
`ineffectual.
`20 mg.,
`except
`of
`ceived
`that
`amount.
`the
`children’s
`ages
`
`amount,
`on this
`sort
`of any
`no response
`them showed
`was
`therapeuti-
`could
`tolerate
`dose
`they
`the
`largest
`The
`remaining
`patients
`all
`received
`daily
`doses
`one
`boy who
`tolerated
`30 mg.
`very
`well
`and
`re-
`There
`was
`no
`apparent
`relationship
`between
`or weights
`and
`their
`reaction
`to benzedrine.
`
`COMMENT.
`
`spectacular
`was
`
`in
`
`about
`brought
`behavior
`change
`the most
`Possibly
`the
`per-
`school
`improved
`remarkably
`of
`benzedrine
`the
`use
`by
`more
`the
`is
`This
`the
`children.
`half
`of
`approximately
`formance
`intelligence
`good
`patients
`were
`these
`that
`when
`we
`note
`striking
`personality
`any
`adequate
`attention
`they
`were
`receiving
`that
`and
`Moreover
`their
`school
`progress.
`which
`might
`affect
`disorders
`sympathetic
`where
`specially
`trained,
`in
`already
`a
`school
`were
`an
`in
`basis
`or
`pupils
`either
`on
`individual
`with
`dealt
`their
`teachers
`dose
`see
`a
`single
`daily
`of
`benzedrine
`pro-
`groups.
`To
`small
`very
`school
`performance
`than
`com-
`the
`a greater
`improvement
`duce
`in
`working
`in
`a most
`favorable
`setting,
`staff
`efforts
`a capable
`bined
`demoralizing
`to
`the
`teachers,
`had
`not
`the
`have
`all
`but
`would
`improvement
`so
`gratifying
`a practical
`viewpoint.
`
`of
`for
`
`they
`
`of
`been
`been
`
`from
`
`for
`
`plausible
`entirely
`No
`evident
`is
`formance
`was
`However,
`used.
`show
`this
`did
`not
`of
`them
`that most
`the
`group
`half
`of
`degree
`in the
`notable
`As
`far
`as
`improvement
`the
`teachers
`were
`cerned
`performance,
`since
`speed
`of
`quantity
`output
`were
`It
`appears
`paradoxical
`in
`produce
`subdued
`behavior
`that
`borne
`in mind,
`however,
`have
`central
`nervous
`system
`portions
`stimulation
`of
`these
`ture
`of
`reduced
`activity
`through
`
`acceleration
`fact
`that
`the
`whole
`school,
`in
`ways
`to
`mood
`
`school
`of
`stimulating
`group
`of
`spite
`of
`in
`the medication.
`changes
`shared
`
`a
`
`per-
`drug
`children
`the
`fact
`Only
`to
`
`a
`
`school
`by
`
`subjects
`changes
`degree
`
`of
`
`con-
`was
`arithmetic
`in
`accuracy
`
`and
`
`affected.
`should
`a stimulant
`known
`to be
`should
`It
`of
`the
`children.
`levels
`of
`of
`the
`higher
`as
`their
`function,
`and
`produce
`the
`clinical
`voluntary
`control.
`
`be
`the
`that
`pic-
`Pre-
`
`this
`
`the
`of
`
`reason
`aside
`from
`at
`half
`least
`striking
`response
`responded
`in
`other
`showing
`favorable
`school
`improvement.
`individual
`in
`most
`impressed
`of
`comprehension,
`all
`favorably
`that
`a drug
`half
`portions
`inhibition
`might
`indeed
`increased
`
`Page 17 of 20
`
`

`

`1937]
`
`.
`
`CHARLES
`
`BRADLEY
`
`583
`
`20
`
`it
`
`by electro-
`is suggested
`be the
`this may
`that
`evidence
`sumptive
`case
`clinical
`ex-
`part
`of
`the
`formed
`studies,U
`which
`encephalographic
`the
`of
`abnormalities
`Definite
`patients.
`amination
`in
`30
`of
`our
`of whose
`children,
`eight
`were
`noted
`in
`brain
`rhythms
`these
`of
`II
`wave”
`form
`characteristic
`of
`slow
`the
`“spike
`and
`records
`showed
`epilepsy.14
`with
`petit
`and
`waves”
`seen
`in
`patients
`mal
`the
`“seizure
`children
`whose
`erratic,
`irritable
`and
`aggressive
`behavior
`in
`some
`that
`epileptic
`patients.15’
`It may
`be
`significant
`that
`of
`resembles
`16
`of
`these
`children
`with
`“seizure
`waves”
`dis-
`one
`all
`but
`became
`subdued
`under
`the
`influence
`of
`benzedrine.
`Since
`has
`tinctly
`been
`noted
`that
`“slow
`waves”
`in
`the
`electroencephalogram
`also
`likewise
`present
`in a number
`of
`conditions
`where
`consciousness
`are
`impaired,
`it
`has
`been
`suggested
`that
`their
`appearance
`indicates
`is
`impaired
`cortical
`functions.17
`One
`might
`postulate
`that
`a stimulat-
`ing
`drug
`like
`benzedrine
`tend
`to
`arouse
`this
`impaired
`cortical
`may
`activity
`and
`alleviate
`any
`behavior
`disorder
`resulting
`therefrom.
`necessary
`Further
`studies
`are
`to
`confirm
`this.
`There
`are,
`course,
`a great
`many
`other
`of
`and
`into
`the
`genesis
`clinical
`manifestation
`problem.
`Complete
`understanding
`their
`response
`to
`benzedrine
`with
`these
`many
`factors.
`children
`this
`series
`child’s
`a
`characteristics
`type,
`intelligence
`
`possible
`of
`fact
`the
`of
`correlation
`awaits
`preliminary
`very
`to
`be
`benzedrine
`to
`sex,
`past
`special
`
`From
`seems
`there
`response
`of
`
`age,
`and
`
`factors
`any
`child’s
`children
`that
`this
`vari-
`of
`observations
`of
`little
`apparent
`and
`the
`con-
`history,
`physical
`mental
`abilities
`
`enter-
`be-
`
`or
`
`in
`
`in
`between
`clinical
`reaction
`
`ing
`havior
`vary
`ability
`the
`30
`relationship
`ventional
`condition,
`disabilities.
`of
`In
`spite
`and
`patients,
`its
`prolonged
`to
`await
`
`the
`the
`use
`
`attractive
`apparent
`in
`the
`complete
`
`results
`low toxicity
`hands
`of
`other
`knowledge
`
`in this
`obtained
`drug
`the
`of
`observers,6’
`t