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`US008138229 B2
`
`(12) United States Patent
`Desai et al.
`
`(1U) Patent No.:
`(45) Date of Patent:
`
`US 8,138,229 B2
`*Mar. 20, 2012
`
`(54) cO.\tI'OSITIO."S ANI) M.ET IIOVS OF
`DEI.lVERY OF I'IlAlli\l,\ COI,oGICA I.
`M-;.~ NTS
`
`(75)
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`[n" ... 'llors: Neil r. Dt."!ilti. Los.<\,.Ilgc k s. CA (US):
`Patrick Sooll-Shil)lI\1.. Lus Angeles, CA
`(US); Vuong Trieu, Calabasas, CA (US)
`
`(73) Assignee: Abra:ds Blosclo<nct, LLC. Los Angeles.
`CA (US)
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`( . ) NOIi<:c"
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`Suhjcctlo any cli ~ln imer> Ihe tern, ofthi.
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`
`This patenl is subjt'Cl 10 a Icmlinal dis-
`claimer.
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`(21 ) Appl. No.: 121910,693
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`(22) Filed:
`
`Oct. 22, 2(1 10
`
`(65)
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`Prior p"blicolion n"tu
`us 20 1110301248AI
`Dce. 8,2011
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`ndalcd U.S. App lic a tion n .. ta
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`(63) Contiou:alio n of npplic:lIioo No. 111553.339. lilL>d on
`Oct 26. 2006. now Pal. No. 7.820.788. which b a
`continuation of application No. 101731,224, filed on
`fk'C_ 9, 2003, nowah.arxloncd
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`(60) Provisional applicalion No. 6Of432.317. fill'd on IX"C.
`9. 2002. provisional appl icalion No. 601526.544. filt.'t!
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`6W526,773, filed on Dec . 4, 2003, provi sio nal
`ap plication No. 601527.177. filed on Dec. 5. 2003.
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`(51)
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`(Continued)
`
`FOREIGN PATENT !X>CUMENTS
`0227593 Al
`711987
`(Continued)
`
`OTHER PUBLICATIONS
`
`Kon Fill,,1 Office Ac{ion m,tiled on Nov. 21. 20 11, f",U.s . ,\ppl. l\o
`12/422.191. filed Apr. 10.2009.20 1"'It«.
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`Primary Exominl.'r Marsh;) Tsay
`(74) AI/orne)'. Agent, or Firm - Morrison & Foers ter LLI'
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`The prt"SCnl invenlion rdales to a pharmaC(:ulical composi·
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`U.S. PATENT OCX:UMENTS
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`101 1996 Soon·Shiong <>1 aL
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`Apotex v. Abraxis - IPR201 8-00151 , Ex. 1001 , p.OI of25
`
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`Apotex v. Abraxis - IPR20 18-00 15 1, Ex. 100 I, p.04 of 25
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`us 8,138,229 82
`Page 5
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`U.S. Appl.l\o 121479.710, inlcr1l.1lionally filed on Jun. 5, 2009. for
`Desai cr 31
`U ,S. Appl. No I3IIJJH.287. internationally filc<l on MM. 1, 20 11 ro r
`Dosa L ~' al
`U.S. APrI. :->0. 13/073,824. intcrnatiOllallyfilcdonM", 28. lOl l fOJ
`D<:s.o.i <!'\ a1.
`U.S. Appl. "In 13f07J,AAI. inr~m",j",,"lIyti lc<lnn Mar. 28. 2011 for
`Do,a; c l al .
`U.s. Appl. :-'-0. 13/ 133,367. inrcrnllliOllRllyfikdonDcc. 11. 200'). fOJ
`T ri"u cI ~l
`U.S. Appl. No 131228.323. internationally filed On Scp. 8. 201 1. fOJ
`lksai C1 al.
`U.S. App! No 131263.723. internationally fiI~~1 on Apr. 9, 2010. for
`Desai <!'\ 31.
`U.S. ArrJ. No_ 13/255,893, inh:maliOllallyf,blon Mar. 12.1010. fOl
`l)cuiC131.
`Fiflll I::.>;amination RqxlI1 issued on Jan . 7. 2008. hy Tn,]i.," Parcnt
`om~" ('"Conlfolk.,- or P<IIcnts") f", Indian PaI",nl Applic31ion No.
`2899!D£LNPI2005. owned by Applicant American Bios<icncc. loc.
`(n<lW ··Ahr .. ~is BioSc ;"n~ ... LLC·). 12 pases
`Response 10 Fil S! E.~a.ll1ination Rcpon filo:don 1:111. 6. 2009. wilh Ihe
`Indian Palent ( mice. by Applicanl fo, In,li,," 1""",,1 Arrlicillion No .
`2899: D£LNPI2005. 151'''g~'S
`PIc-grant opJX.>silion on Scp. 4. 2008. submil1ed by Opponcnl
`("N. I"o PIla,,,,,, LId .") against Indian Patenl Applicatioll No_ 28991
`DELNPI2005. 149 page;
`Reply filed by AW1icant on Jan. 9. 200'1. 10 tile prc·granl oppos ilion
`fik-d by 01'1'0""01 again:;! Indian Pal~nt AI'I>l iullioo 1\0. 28991
`DELNPI2005. 30 p<1j;<.'S (0I.~1
`A~<li tiQ nal Sufl",i .. ion from Opponcm d.tc<l Mal. 10. 2000. IQ 'he
`Indian Patenl om"" in ''''SPOnoe 10 Ih" reply filed by Applicanl. 179
`p.ag~ s.
`
`Submission from Appl ic!lIIt <i.o.lcd Apr. 8, 2009 to Indian I'alent
`om"c. p<:rlaining to the pro" • .',,,,liun oflndian Palenl ApplicaI'Qn No.
`11!991lJELNI'I200.s. I J4 pages
`Submission filed by Applicrutt o n May 4. 2009. pcnaining to argu(cid:173)
`menl" m.de rluring Ihe oml heruing of Ihe p'C'$'ant oppo-si lion of
`Indian Patent ApplicaliQn 1\0. 2899/DELNP/2005. held on Apr. 9.
`2009.l.>ocfun: thc Controllerofl'alents. 22 p"-!!"S.
`Ocrision oflhe Indian ConlrollcrofPatentsdatcd Jul. 24. 20{)'), with
`{c'pcClto the pre-grnnt oppos ition filed 3woinltlntlian Palelt1 Appli(cid:173)
`~ation No. 2~99IVl :I.NI'12005. 3] Me ..
`Ci~il Writ Petition flied ,\pplicantlP<'IitiQfl'" ("Ab.a-'<is BioScience.
`LLC")witb the Iligh COIm ofl)d hi At N~w Lklhi. India. o n No". 26.
`2009. challenging the decision o f Ihe Indian Controller of Palent!
`daTal Jill. 24. 2009.!o refll$/; !he ,gmn! of I"dian p..!~n! A"plical i""
`No. 2899IDELNP/200SI300. 29 pages 101aJ.
`Appeal filed by Applicant/Appellant CAb.axi. BioScience . J I.C''')
`,,·ith lhe Intdkdllall'ropcny Appeal Board on N",",. 2i .2009. aWlins!
`the dec ision of the Indian CQntroi!er of Pa!ents drued JuL 24. Ww.
`refll~ing!" gran! Indian Patent AI' plicalion NQ 2899/1)8\"1.1'.'2005 .
`71 p<lses.
`NQlicc from Intellect".,l Property A p[>dl.lIc Ilo.mlto {~enIlRc,
`"",",knl :-10. 4 (MNaK" Phanna L td . ")dal<-d Jan. 11.2010. o