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`CURRICULUM VITAE
`TIMOTHY PATRICK HARRIGAN, ScD, MBA, PE
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`CONTACT INFORMATION
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`OFFICE :
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`Johns Hopkins University Applied Physics Laboratory
`Mail Stop MP2-143
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`11000 Johns Hopkins Road
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`Laurel, MD 20723
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`443-778-5943
`508-740-8614 (cell)
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`HOME:
`14 High St.
`Franklin, MA 02038
`508-541-3949
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`E-MAIL ADDRESS: Timothy.Harrigan@jhuapl.com
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`QUALIFICATIONS:
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` Extensive consulting experience in mechanics of bicycles and bicycle accessories
` A deep technical background in mechanics, materials and physiology as they relate to
`medical applications
` Extensive experimental experience in computer-controlled data acquisition using video
`buffers, strain gauges, ultrasound, and similar sensors.
` Strong communication skills: over 30 published papers, extensive meeting presentations,
`and university teaching experience
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`CERTIFICATIONS:
`Registered Professional Engineer, State of Texas #86769
`Registered Patent Agent, US Patent and Trademark Office, Registration #51,784
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`POSITIONS HELD:
`SENIOR RESEARCH ENGINEER, Johns Hopkins University Applied Physics Laboratory, August 2009
`to present
` Analysis of injuries to human anatomical structures due to IED and projectile threats
` Model validation against explosive and shock-tube tests on phantoms
` Development of anatomically accurate computational models for injury analysis
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`SENIOR ENGINEER, Foster-Miller, January 2005 to August 2009
` Consulting Firm, in the Structures and Transportation Group
` Biomechanics of Injuries, Crashworthiness, and injury protection
` Medical device Research and Development
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`SENIOR ENGINEER, Exponent Failure Analysis Associates, January 2000 to January 2005
` Consulting Firm, Full-time employee in the Biomechanics Practice
` Medical Device Analysis: Materials selection, Stress analysis, Patent infringement. Includes total
`joint replacements, stents, intravenous tubing, dialysis machines, catheters, vascular occlusion
`devices.
`Injury Analysis: Biomechanics, force and stress analysis of biological structures. Includes
`industrial injuries (oil rigs, construction sites) and accident analysis (automobile, bus, industrial
`equipment)
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`DIRECTOR OF BUSINESS DEVELOPMENT, Resmed Inc. July 1999 to October 1999
` Manufacturer of Continuous positive Airway Pressure Devices. Tasked with developing
`applications in cardiology and stroke rehabilitation.
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`DIRECTOR OF RESEARCH, Department of Orthopedic Surgery, University of Texas at Houston,
`Medical School, Sept. 1993 to December 1999
` Supervised orthopedic resident research projects
` Developed experimental and computational models for orthopedic implants
` Developed experimental and computational models for bone circulation
` Did research on cement pressurization around total hip implants
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`ASSOCIATE PROFESSOR (25% salary), Department of Mechanical Engineering, Rice University,
`Houston, TX, Sept. 1993 to June 1999
` Taught courses in biomechanics, mechanical design, and stress analysis
` Supervised Graduate Students
` Was part of a team that got $5M funding from the Whitakerfoundation for the start-up of an
`Undergraduate Bioengineering Curriculum
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`ADJUNCT ASSOCIATE PROFESSOR, Department of Mechanical Engineering, Cullen College of
`Engineering, The University of Houston, 1994 to June 1999.
` Supervised Graduate Students
` Collaborated in research on elastography
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`DIRECTOR OF RESEARCH, Department of Orthopedics, University of Missouri- Kansas City Medical
`School Kansas City, MO, August 1990 to September, 1993.
` Supervised orthopedic resident research projects
` Developed experimental models for bone machining processes for orthopedic implants
` Developed computational bone remodeling simulations
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`ASSISTANT IN ORTHOPEDICS (BIOMECHANICS); Massachusetts General Hospital; April 1985 to
`July 1990.
` Conducted research on cemented and un-cemented total hip replacements
` Did research on bone cement porosity, and methods to minimize it.
` Developed experimental capabilities to characterize cancellous bone around implants
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`RESEARCH ASSOCIATE; Dept. of Mechanical Engineering, Massachusetts Institute of Technology;
`April 1985 to July 1990.
` Supervised students, collaborated on research with MIT professors
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`RESEARCH ASSISTANT, Department of Mechanical Engineering, Massachusetts Institute of
`Technology, under R. W. Mann, June 1982 to March 1985.
` Thesis research on the MIT hip project, sponsored by a Whitaker Health Sciences Fund
`fellowship
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`TEACHING ASSISTANT, Department of Mechanical Engineering, Massachusetts institute of
`Technology, in courses 2.31 and 2.32; Mechanical Behavior of Materials I and II, Taught by
`F. A. McClintock and A. S. Argon, Sept. 1981 to May 1982.
` Supervised labs, instructed students on the use of testing machines
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`RESEARCH ENGINEER, Orthopedic Biomechanics Lab, Mayo Clinic, Rochester, MN. July 1980 to
`August 1981.
` Did experimental and computational research on the mechanics of the elbow, cinluding
`determination of moment arms for muscles and constrained optimization for force analysis
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`UNDERGRADUATE RESEARCH, Full time Summer 1978 and 1979 and part time during the academic
`year, MIT Newman Laboratory for Biomechanics and Human Rehabilitation, MIT, and Orthopedic
`Research Lab, Mass. General Hospital.
` Did research on cancellous bone, resulted in a 1980 paper presented at the ORS.
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`EDUCATION:
`UNIVERSITY OF HOUSTON, HOUSTON, TX
`MASTER OF BUSINESS ADMINISTRATION, December 1998 GPA 4.0/4.0
`Course concentration in Marketing and Entrepreneurship
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`MASSACHUSETTS INSTITUTE OF TECHNOLOGY, CAMBRIDGE, MA.
`Sc. D. MECHANICAL ENGINEERING, APRIL 1985. GPA 4.6/5.0
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`Doctoral Thesis: Bone Compliance and Its Influence in Human Hip Joint
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`Lubrication. Thesis Supervisor, Prof. R. W. Mann.
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`Honors: Won a Whitaker Health Sciences Fund Fellowship for 1983-1984; renewed
`1984-1985. Included full tuition and stipend.
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`MASSACHUSETTS INSTITUTE OF TECHNOLOGY, CAMBRIDGE, MA.
`B. S. MECHANICAL ENGINEERING, JUNE 1980, GPA 4.5/5.0
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`Honors: Pi Tau Sigma, Treasurer; Tau Beta Pi.
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`MOUNT SAINT CHARLES ACADEMY, WOONSOCKET, RI
`HIGH SCHOOL DIPLOMA, JUNE 1976, GPA 4.0/4.0
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`Honors: Science award, Graduated after Third Year.
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`COURSES TAUGHT:
` ME 311 Mechanics of Deformable Bodies, Department of mechanical Engineering, Rice
`University, Spring 1998
` ME 401 Mechanical Design Applications, Department of Mechanical Engineering, Rice
`University, Fall 1997 and 1998
` ME 380 Introduction to Mechanical Effects in Tissues, Department of Mechanical Engineering,
`Rice University. Undergraduate level. Developed and Taught, Spring 1994 to 2001.
` ME 580 Mechanical Models for Tissues and Physiologic Systems, Department of Mechanical
`Engineering, Rice University. Graduate level. Developed and Taught, Spring 1994 to 2001.
` Biomechanics Summary courses for Orthopedic Residents: University of Missouri - Kansas City;
`University of Kansas Medical School, Kansas City, KS; U of Texas Medical School at Houston.
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`PUBLICATIONS (Partial):
`REFEREED SCIENTIFIC PAPERS:
`1) Harrigan, T. P., Mann, R. W.: Characterization of Microstructural Anisotropy in Orthotropic
`Materials Using a Second Rank Tensor, J. Materials Science 19:761-767, 1984.
`2) An, K. Takahashi, K., Harrigan, T. P., Chao, E. Y.: Determination of Muscle Orientations and
`Moment Arms, J. Biomechanical Engineering 106:280-282, 1984.
`3) Rey, R. M., Paiement, G. D., McGann, W. M., Jasty, M., Harrigan, T. P., Burke, D. W., Harris, W.
`H.: A Study of Intrusion Characteristics of Low viscosity cement, Simplex P, and Palacos Cements in
`Bovine Cancellous Bone Model, Clin. Orth. 215:272-278, 1987.
`4) Harrigan, T. P., Mann, R. W.: State Variables for Modelling Physical Aspects of Articular Cartilage,
`International Journal of Solids and Structures 23(9), 1205-1218, 1987.
`5) Harrigan, T. P., Jasty, M., Mann, R. W., Harris, W. H.: Limitations of the Continuum Assumption in
`Cancellous Bone, J. Biomechanics 21(4), 269-275, 1988.
`6) Davies, J. P., Jasty, M., O'Connor, D. O., Burke, D. W., Harrigan, T. P., Harris, W. H.: The effect Of
`Centrifuging Bone Cement, Br. J. Bone and Joint Surg. 71B:39-42, 1989.
`7) Harrigan, T. P., Kareh, J. A., Harris, W. H.: Failure Mechanisms in the Push-out test: A Finite
`Element Study, J. Orthopedic Research, 8(5):678-684, 1990.
`8) Jasty, M., Davies, J. P., O'Connor, D. O., Burke, D. W., Harrigan, T. P., Harris, W. H.: Porosity of
`Various Preparations of Acrylic Bone Cements, Clin. Orthop. and Rel. Res., 259:122-129, 1990.
`9) Schutzer, S.F., Jasty, M., Bragdon, C.F., Harris, W. H.:A Double-Blind Study on the Effects of a
`Capacitively Coupled Electric Field on Bone Ingrowth into Porous-Surfaced Canine Total hip
`Prostheses, Clin. Orthop. 260:297-304, 1990.
`10) Harrigan, T. P., Harris, W. H.: A Finite Element Study of The Effect of Radial Interface Gaps On
`The Contact Areas and Pressures in Uncemented Cylindrical Femoral Total Hip Components, J.
`Biomechanics, 24(1):87-91, 1991.
`11) Harrigan, T. P., Harris, W. H.: A 3D Nonlinear Finite Element Study of the Effect of Cement-
`Prosthesis Debonding in Cemented Femoral Total Hip Components, J. Biomechanics, 24(11):1047-
`1058, 1991.
`12) Harrigan. T. P., Kareh, J. A., O'Connor, D. O., Burke, D. W., Harris, W. H.: A Finite Element Study
`of the Initiation of Failure of Fixation in Cemented Femoral Total Hip Components, J. Orthopedic
`Research 10(1):134-144, 1992.
`13) Harrigan, T.P., Hamilton, J.J.:An Analytical and Numerical Study of the Stability of Bone
`Remodelling Theories: Dependance on Microstructural Stimulus, J. Biomechanics, 25(5):477-488,
`1992.
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`14) Harrigan, T.P., Hamilton, J.J.: Optimality Conditions for Finite Element Simulation of Adaptive
`Bone Remodelling, Int. J. Solids Structures 29(23)2897-2906, 1992
`15) Harrigan, T.P., Hamilton, J.J.:Bone Strain Sensation Via Transmembrane Potential Changes in
`Surface Osteoblasts: Loading Rate and Microstructural Implications, J.Biomechanics, 26(2):183-
`200, 1993.
`16) Harrigan, T.P., Hamilton, J.J.:Finite Element simulation of Adaptive Bone Remodelling: A Stability
`Criterion and A Time Stepping Method, International Journal for Numerical Methods in Engineering,
`36:837-854, 1993.
`17) Harrigan, T. P., Hamilton, J. J.: Bone Remodeling Adjacent to Total hip Replacements: A Naturally
`Occurring Material Design Problem, Journal of Computer-Aided Materials Design 1:27-40, 1993.
`18) Page, A. E., Allan, C., Jasty, M., Harrigan, T. P., Bragdon, C. R., Harris, W. H.:Determination of
`Loading Parameters in the Canine Hip Joint, J. Biomechanics 26:571-579, 1993
`19) Harrigan, T. P., Hamilton, J. J.: Bone Remodeling and Structural Optimization, Journal of
`Biomechanics, 27(3):323-328, 1994.
`20) Harrigan, T. P., Hamilton, J. J.: Necessary and Sufficient Conditions for Global Stability and
`Uniqueness in Finite Element Simulations of Adaptive Bone Remodeling, International Journal of
`Solids and Structures, 31(1):97-107, 1994.
`21) Jasty, M., O'Connor, D. O., Henshaw, R. M., Harrigan, T. P., Harris, W. H.:Fit of Uncemented
`Femoral Component and the Use of Cement Influence the Strain Transfer to the Femoral Cortex", J.
`Orthopedic Research 12(5):648-656, 1994.
`22) Cowin, S. C., Luo, G. M., Sadegh, A. M., Harrigan, T. P.: On the Sufficiency Conditions for the
`Stability of Bone Remodeling Equilibrium, J. Biomechanics 27(2):183-186, 1994.
`23) Harrigan, T. P., A Nonlinear Model for Myogenic Regulation of Blood Flow to Bone: Equilibrium
`States and Stability Characteristics, Annals of Biomedical Engineering, 24:211-221, 1996.
`24) Harrigan, T. P., Hamilton, J. J., Reuben, J. D., Toni, A., Viceconte, A.: Bone Remodeling Adjacent
`to Total Hip Replacements: An Optimal Structures Approach, Biomaterials, 17:223-232, 1996
`25) Harrigan, T. P., Reuben, J. D.: “Mechanical Model for Critical Strain in Mineralizing Biological
`Tissues: Application to Bone Formation in Biomaterials”, Biomaterials 18:877-883, 1997.
`26) Harrigan, T. P.,:”Regulatory Interaction between Myogenic and Shear-Sensitive Arterial Segments:
`Conditions for Stable Steady States,” Annals of Biomedical Engineering 25:635-643, 1997.
`27) Harrigan, T. P.:”Limiting Models for Calcification in Fibrous Tissues Adjacent to Orthopedic
`Implants: Variational Indicator Functions and Influences of Implant Stiffness,” Bulletin of
`Mathematical Biology, 1998
`28) Harrigan, T. P., Biegler, F. B., Reuben, J. R.:"Stability and Optimality in Finite Element Simulation
`of Adaptive Bone Remodeling", Comments on Theoretical Biology, 5(1):1-47, 1998.
`29) Dozier JK, Harrigan T, Kurtz WH, Hawkins C, Hill R.:” Does increased cement pressure produce
`superior femoral component fixation?”, J Arthroplasty Jun;15(4):488-95, 2000.
`30) Konofagou EE, Harrigan T, Ophir J., Shear strain estimation and lesion mobility assessment in
`elastography,” Ultrasonics Mar;38(1-8):400-4, 2000.
`31) Konofagou EE, Harrigan TP, Ophir J, Krouskop TA:”Poroelastography: imaging the poroelastic
`properties of tissues,” Ultrasound Med Biol Oct;27(10):1387-97, 2001.
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`LETTERS TO THE EDITOR
`1) Harrigan, T. P.: letter to the editor, Journal of Bone and Joint Surgery, September, 1986.
`2) Harrigan, T. P.: Cartilage is Poroelastic But Not Biphasic, J. Biomechanics 20(8):827, 1987.
`3) Davies, J. P., Harrigan, T. P.:Fatigue Properties of Acrylic Bone Cement: S-N, P-N, and P-S-N data,
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`J. Biomedical Materials Research 23(A2 Suppl.): 261-4, 1989.
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`MEETING PRESENTATIONS (partial)
`1) Harrigan, T. P., Oh, I., Harris, W. H., Mann, R. W.: The Anisotropic Properties of Cancellous Bone,
`Trans. Orthopedic Research Society 5:60, 1980.
`2) Harrigan, T. P., Oh, I., Harris, W. H., Mann, R. W., Carter, D. R.: The Anisotropic Properties of
`Trabecular Bone, Trans. Northeast Bioengineering Conference, 1980.
`3) Harrigan, T. P., Carter, D. R., Mann, R. W., Harris, W. H.: The Influence of Apparent Density and
`Trabecular Orientation on the Elastic Modulus of Cancellous Bone, Tran. Orthopedic Research
`Society 6:277, 1981.
`4) An, K., Harrigan, T. P., Cahill, B. P., Chao, E. Y.: Determination of the Coefficients in Equilibrium
`Equations for Muscles., Biomechanics Symposium, Am. Soc. of Mechanical Engineers 43:101 1981.
`5) Morrey, B. F., An, K., Harrigan, T. P., Kasman, R.: Elbow Joint Stability: a Biomechanical Study,
`Annual conference, American Society for Sports Medicine, 1982.
`6) Harrigan, T. P., Mann, R. W.: The Mean Intercept Length Tensor in Cancellous Bone Mechanics,
`Biomechanics Symposium, American Society of Mechanical Engineers 1983.
`7) Jasty, M., Harrigan, T. P., Rogers, S. P., Weinberg, E. H., Harris, W. H.: Factors Affecting Bone
`Ingrowth into Canine Acetabular Replacements, Trans. Orthopedic Research Society 9:177, 1984.
`8) Harrigan, T. P., Jasty, M., Harris, W. H., Mann, R. W.: Limitations of the Continuum Assumption in
`Cancellous Bone Mechanics, Biomechanics Symposium, American Society of Mechanical
`Engineers, 1984.
`9) Harrigan, T. P., Jasty, M., Mann, R. W., Harris, W. H.: Characterization of Microstructural
`Anisotopy In Cancellous Bone Using A Second Rank Tensor, Trans. Orthopedic Research Society
`10:375, 1985.
`10) Jasty, M., Harrigan, T. P., Greer, J. A., Chen, J. Harris, W. H.: Prediction of directional Variations in
`Material Properties of Human Cancellous Bone Using 3-D Stereologic Technique, Trans.
`Orthopedic Research Society 10:352, 1985.
`11) Harrigan, T. P., Jasty, M., Mann, R. W., Harris, W. H.: Limitations of The Continuum Assumption
`in Cancellous Bone Mechanics, Trans. Orthopedic Research Society 10:353, 1985.
`12) Jasty, M., Jensen, J. F., Burke, D. W., Harrigan, T. P., Harris, W. H.: Porosity Measurement in
`Commercial Bone Cement Preparation and the Effect of Centrifugation on Porosity Reduction,
`Trans. Orthopedic Research Society 10:239, 1985.
`13) Harrigan, T. P., Mann, R. W.: State Variables Used in Physical Modelling of Articular Cartilage,
`Advances in Bioengineering, American Society of Mechanical Engineers, 1985.
`14) Harrigan, T. P., Mann, R. W.: An Anatomic Basis for Stress Induced Bone Remodelling, Advances
`in Bioengineering, American Society of Mechanical Engineers, 1985.
`15) Henshaw, R. M., Harrigan, T. P., Jasty, M., Mann, R. W., Harris, W. H.: "Three Dimensional Map of
`the Proximal and Distal Human Femur and Proximal Human Tibia", Trans. Orthopedic Research
`Society 11:41, 1986.
`16) Harrigan, T. P., Jasty, M., Henshaw, R. M., Harris, W. H., Mann, R. W.: Statistical Measurements in
`Cancellous Bone, Trans. Orthopedic Research Society 11:333 1986.
`17) Jasty, M., Rubash, H., Paiement, G., Bragdon, C., Harrigan, T. P., Harris, W. H., "Distribution of
`Bone Ingrowth Into Proximally Coated Femoral Porous Canine Total Hip Replacements, Trans.
`Orthopedic Research Society 11:344, 1986.
`18) Jasty, M., Harrigan, T. P., Henshaw, R. M., O'Connor, D. O., Harris, W. H.: Residual Strains
`Produced in the Proximal Femur During Rasping and During the Insertion of Uncemented Metal
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`Femoral Components, Trans. Orthopedic Research Society 12:399, 1987.
`19) Harrigan. T. P., Jasty, M., Harris, W. H.: The Effect of Surgical Precision on the Mechanics of Press-
`fit Femoral Components: A Finite Element Study, Trans. Orthopedic Research Society 13:307, 1988.
`20) Jasty, M., Henshaw, R. M., O'Connor, D. O., Harrigan, T. P., Harris, W. H.: Strain Alterations in the
`Proximal Femur With an Uncemented Femoral Prosthesis, Emphasizing The Effect of Component
`Fit. An Experimental In Vitro Strain Study, Trans. Orthopedic Research Society 13:335, 1988.
`21) Kareh, J., Harrigan, T. P., Burke, D. W., O`Connor, D. O., Harris, W. H.: Strains in the Cement
`Mantle Surrounding The Total Hip Replacement Femoral Component. Comparison to Experimental
`Data. Trans. Orthopedic Research Society 13:344, 1988.
`22) Harrigan, T. P., Jasty, M., Davies, J. P., Harris, W. H.: Interface Failure Assessed Using Push-out
`Tests: Example: The Cement-Prosthesis Interface, Trans. Orthopedic Research Society 13:501, 1988.
`23) Kareh, J., Jasty, M., Harrigan, T. P., Harris, W. H.: The Effect of Markedly Varying Head Offset,
`Cement Modulus, and Stem Modulus on Stress Transfer Around Total Hip Replacement Prostheses,
`Trans. Orthopedic Research Society 13:528, 1988.
`24) Page, A., Harrigan, T. P., Allen, C., Jasty, M., Mann, R. W., Harris, W. H.: Analysis of the Canine
`Gait Using Bone Pins, Bilateral Force Plates, and Rigid Segment Motion Analysis System, Trans.
`Orthopedic Research Society 13:544, 1988.
`25) Jasty, M., O'Connor, D. O., Harrigan, T. P., Harris, W. H., Page, A.: Stress Alterations in the
`Proximal Femur with Uncemented Femoral Prostheses, Presented at the American Academy of
`Orthopedic Surgeons, Feb., 1988.
`26) Allan, C. D., Jasty, M., Burke, D. W., Harrigan, T. P., Page, A., Bragdon, C., Cargill, E., Harris, W.
`H.: Magnitude, Directions and Patterns of Hip Joint Reaction Forces in Canines Using an
`Instrumented Femoral Prosthesis, Trans. Orthopedic Research Society 14:95, 1989.
`27) Harrigan, T. P., Jasty, M., Harris, W. H., Mann, R. W.: Two-dimensional Connectivity Measurement
`in Cancellous Bone, Trans. Orthopedic research Society 14:101, 1989.
`28) Allan, C., Jasty, M., Harrigan, T. P., Bragdon, C., Cargill, E., Mann, R. W., Murphy, M., Harris, W.
`H.: A Comparison of the Joint Reaction Forces Measured with an Instrumented Endoprosthesis and
`Calculated from Gait Analysis, Trans. Orthopedic Research Society 14:226, 1989.
`29) Bragdon, C., Jasty, M., Russoti, G., Cargill, E., Harrigan, T. P., Harris, W. H.: Patterns of Bone
`ingrowth, Cortical Porosity, and Bone Mass in a Proximally Porous Coated Canine Femoral Implant
`After Six Month Implantation, Trans. Orthopedic Research Society 14:378, 1989.
`30) Harrigan, T. P., Jasty, M., Harris, W. H.: The Effect of Component Elastic Modulus on Stress in
`Uncemented Femoral Components: A Finite Element Study, Trans. Orthopedic Research Society
`14:405, 1989.
`31) Page, A., Jasty, M., O'Connor, D. O., Krushell, R., Russotti, G., Harrigan, T. P., Bragdon, C. A.,
`Harris, W. H.: Stress Shielding Around Proximally Porous Surfaced Femoral Components Six
`Months After Bone Ingrowth and Remodelling in the Canine, Trans. Orthopedic Research Society
`14:576, 1989.
`32) Page, A., Jasty, M., Harrigan, T.P., Bragdon, C., Harris, W.H.: Comparison of Femoral Component
`Stiffness and Extent of Porous Coating on Cortical Strain Alterations After Bone Ingrowth, Trans
`ORS 15:453, 1990.
`33) Harrigan, T.P., Kareh, J.A., Harris,W.H.: A Failure Criterion for Crack Initiation At Pores Applied to
`Bone Cement, Trans, Soc. Biomaterials 13:189, 1990.
`34) Harrigan, T.P., Kareh, J.A., Harris,W.H.:Initial Loosening Mechanisms in Cemented Femoral Stems:
`Debonding at the Cement-metal Interface, Trans. Soc. Biomaterials 13:189,1990.
`35) Harrigan, T.P.: Microstructural Measurements in Cancellous Bone, Trans. First World Congress of
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`Biomechanics P.47, 1990.
`36) Harrigan, T.P.: Transduction of Stress to Cellular Signals, Trans. First World Congress of
`Biomechanics P.51, 1990.
`37) Harrigan. T.P., Harris, W.H.:Mechanical Consequences of Cement-Metal Interface Disruption
`(Debonding) at the Distal Tip Of Femoral Total Hip Prostheses, Trans. ORS 16:503, 1991.
`38) Harrigan, T.P., Harris, W.H.:Collar-Calcar Stress Transfer Decreases Cement Stresses in Femoral
`Total Hip Components Under Rotatory Loads, Trans. ORS 16:501, 1991.
`39) Estok, D.M., Harrigan, T.P., Harris, W.H.: Finite Element Analysis of Cement Strains at the Tip of
`an Idealized Cemented Femoral Component, Trans. ORS 16:504, 1991.
`40) Harrigan, T.P., Kareh, J.A., Harris, W.H.: Initial Loosening Mechanisms in Cemented Femoral
`Stems: Debonding at the Cement-Metal Interface, Trans. ORS 16:520, 1991.
`41) Harrigan, T.P., Hamilton, J.J.:A Mathematical Model for a Bone Remodelling Stimulus: Effects of
`Loading Rate, Microstructure, and Cellular Interconnection, Combined Meeting of the Orthopedic
`Research Societies of USA, Japan, and Canada, 1991.
`42) Harrigan, T.P., Hamilton, J.J.:Stability of Bone Remodelling Simulations: Effects of Density
`Dependent Material Properties and Tissue Stimulus, Combined Meeting of the Orthopedic Research
`Societies of USA, Japan, and Canada, 1991.
`43) Harrigan, T.P., Hamilton, J.J.:Necessary and Sufficient Conditions for the Stability of Finite Element
`Simulations of Bone Remodeling, Proceedings of the Second North American Congress on
`Biomechanics, August, 1992.
`44) Harrigan, T.P., Hamilton. J.J.: Cancellous Bone Density Variations Adjacent to Total Hip Femoral
`Components Can be Simulated Without A Lazy Zone, Trans. ORS 18:534, 1993.
`45) Harrigan, T.P., Hamilton, J. J. "Finite Element Simulation of Bone Remodeling: Time Stepping
`Methods", Presented at the Meeting of the Biomedical Engineering Society, Salt Lake City, Utah,
`October 1992.
`46) Harrigan, T.P., Hamilton, J.J. "Transmembrane Potential Changes in Bone Cells due to Stress-
`induced Extracellular Potentials: A Possible Bone Strain Sensing Mechanism", Presented at the
`Meeting of the Biomedical Engineering Society, Memphis, Tennessee, October 1993.
`47) Harrigan, T.P., Hamilton, J.J., Reuben J.D. "Continuum-level Bone Remodeling as an Optimization
`Process", 12th Annual Meeting of the Houston Society for Engineering in Medicine and Biology,
`February 1994.
`48) Harrigan, T.P., Reuben, J.D. "Continuum Level Bone Remodeling as an Optimization Process",
`Second World Congress on Biomechanics, Amsterdam, July 1994.
`49) Harrigan, T.P., Reuben, J.D. "Bone Remodeling around Intramedullary Stems: A Mechanical Model
`for Axial and Transverse Loads", Presented at the 1994 Fall Meeting of the Biomedical Engineering
`Society, October 1994.
`50) Harrigan, T.P., Reuben , J.D.:"Bone Remodeling Near Implants as an Optimization Process.",
`Presented at the 31st Annual Technical Meeting of the Society of Engineering Science, College
`Station, TX, October 1994.
`51) Harrigan, T.P., Reuben, J.D." Bone Remodeling Around Intramedullary Stems as an Optimization
`Process", Presented at the Inter-meeting of SIROT, Boston, October 1994.
`52) Thomson, R. C., Yazemski, M.J., Powers, J.M., Harrigan, T.P., Mikos, A.G., "Poly (α- hydroxy
`ester)/Short Fiber Hydroxyapatite Foams for Orthopedic Application, Materials Research Society,
`San Francisco, CA October, 1994.
`53) Harrigan, T.P., Reuben, J.D."Bone Remodeling Around Intramedullary Stems as a Stable Structural
`Optimization Process", ASME Winter Annual Meeting, Chicago, November 1994.
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`Timothy P. Harrigan ScD MBA PE
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`54) Harrigan, T.P., Reuben, J.D."Bone Remodeling Around Intramedullary Stems as an Optimization
`Process: Results for Side Loads and Bending Moments", 13th Annual Houston Conference on
`Biomedical Engineering, February, 1995.
`55) Harrigan, T. P., Biegler, F.B., Reuben, J.D. "Bone Remodeling around Femoral Total Hip
`Components Using A Stable Optimization Approach, Third US National Congress of Computational
`Mechanics, Dallas, TX, June 1995.
`56) Harrigan, T. P., Reuben, J. D. "Physical Implications of a Rate-Sensitive Bone Remodeling Stimulus:
`Stability can be Achieved, but Wolff's Law is Violated in a Subspace", ASME Summer
`Bioengineering Conference, Beaver Creek, Colorado, 1995.
`57) Harrigan, T. P., "Shear-Controlled Dilation in Single and Branched Arterioles Leads to Unstable
`Behavior Which Can be Stabilized by Series Fluid Resistances", ASME Summer Bioengineering
`Conference, Beaver Creek, Colorado, 1995.
`58) Harrigan, T. P., Odgaard, A., Reuben, J. D., "Comparison Between a Two-State Markov Model and
`Intercept Measurements Shows Small-Scale Structural Order, ASME Summer Bioengineering
`Conference, Beaver Creek, Colorado, 1995.
`59) Harrigan, T. P.,"Shear-Controlled Dilation in Single and Branched Arterioles Leads to Unstable
`Behavior Which Can be Stabilized by Series Fluid Resistances", Annual Meeting of the Biomedical
`Engineering Society, Boston, MA, October, 1995.
`60) Harrigan, T. P., Biegler, F. B., Reuben, J. D.,"Bone Remodeling Around Femoral Total Hip
`Replacements: Results Using a Stable Finite Element Method", Annual Meeting of the Biomedical
`Engineering Society, Boston, MA, October 1995.
`61) Harrigan, T. P., Odgaard, A., Reuben, J. D., "Intercept Measurements in Cancellous Bone Show a
`Non-Random Structure", Annual Meeting of the Biomedical Engineering Society, Boston, MA,
`October 1995.
`62) Harrigan, T. P., "A Nonlinear Model for Myogenic Regulation of Blood Flow to Bone: Equilibrium
`States and Stability Characteristics", Annual Meeting of the Biomedical Engineering Society,
`Boston, MA, October 1995.
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`Timothy P. Harrigan ScD MBA PE
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