PROf 961
`GLY <
`GLY
`SER s
`SER(.96)
`lEUt.981
`ARG( 96)
`r
`SER StR
`ALA ALA >
`·
`1' LA
`CYS
`CYS CYS ' S VS S
`ALA ALA <
`ALAj 951
`SER( 971
`GlY( 951
`PHE( 97)
`s G -��HR
`llWI
`�� �i�
`-fR or
`� ASN VAL
`VAL VAL VAL '/A. . '· VA. .: • \;AL
`'· • TP• l 1,I
`TR0P TRF' lRF'
`TAP
`ARG(.951
`
`ARG ARG PRO ARG ARG ARG ARC A.AG
`GLN(95)
`ALA VAL ALA ALA ALA ALA ALA A.LA
`GLN GlN GL V GlN GlN GLN GLN QLN
`PRO( 95)
`
`PRO THR PRO PRO PRO PRO PRO PRO
`GlY
`
`GLY GlY GLY GLY GLY GLY GlY GiLY
`L YS( 951
`LYS lYS ARG
`LEU( 951
`GLV GlY GlY
`LEU LEU LEU
`GlU GLU
`TRP TAP
`TRP
`95)
`VAL(
`
`-:'�- -
`-_. -�
`-
`-
`...
`3 1822 01003 0666 ·:.u
`- 'f ....
`.. .. _.,.,... -·.
`-
`HP VA(.
`7 �
`VM.
`GLU VM.
`GLU
`... VAJ..
`GLU. GLu
`GLU VM.
`lL V,t.j.
`GLU VAJ..
`GLU Vllil GLN
`
`GLU VAL GLU VAL
`GLU VAL
`GlU
`
`GLU GLU GLU VAL
`VAL VAi.
`: · l 11� 11·niiilt�1l11rn111�1rn
`VAt VAt.
`GLN GLN
`GLN LEU
`Gll" LEU
`GLN LEU
`
`GLN LEU GLN LEU
`GLN
`GLN LEU
`GLN LEU
`GLN LEU
`
`GLN GLN GLN LEU
`tu r��
`LEU LEU
`LEU
`LEU
`LEU LEU
`G s. Ot Gl ..
`I
`
`AL leu leu leu VAL VAL f.tu VAL VAL VAL VAL VAL 1eu \/Al VAL
`GLU th•
`VAl
`VAL
`6
`IP GlU GLU GlU GlU GLU GlU GLU GlU GLU GLU GlU GLU GlX
`GLX SER
`GlU SER GLY GLY
`�G�t�Y�vG�t�v� Gv'�tv�·�c�t�v�·�a.e�� �t� �t� ��� �t� �t� �t� �t� �t� �t� �t� �t� �t� �t�
`8 GLYt 991
`GLY
`GLY
`9 GLYl.991
`
`
`GLY GLY Gl' (;LY GLY GLY GLY GLY GLY GLY GLY GLY GLY GLY GlY GlY GLY GlY
`GLY
`GLY
`10 11 12 13 ,.
`GLV lY \,
`GlY
`GlY
`GLY
`'· l LY OLY
`.... ·� SH'i � H �tH ::>t:H St:.•<1 �· H �ll1 ,') ... :>f:k
`:>tR :,f;f, :>bi srn �EH SER
`fil$1 "'QU1''1 N": ·tci" 's.·. o;: �
`lEU
`LEU
`LEU ,,.
`� GU Pfl( Gl.'
`1)'$
`VAL
`VAL
`�'" o: ·::Euu llfll1·� s o"" '"I!! �� �:
`GLN PRO
`GLX
`�=� ��;; pl L�""
`PRO
`PRO
`GLY
`GLY
`GLY
`R Ell R S •·
`:t 17 ,. 19
`GLY
`GlY
`GLV
`LY GLY
`:a
`AL ,,
`SER
`SER lEU
`SER
`A lA LA A ALA A , •
`ARO
`LEU
`LEU
`LEU
`ARG
`ARG
`ARG
`SEii
`LEU
`LEU
`LEU
`lEU SER
`SER SER
`SER CYS ALA ALA
`J-7s At.A ALA
`CYS ALA ALA
`CYS CVS
`•I A ALA ALA
`CY$ At.A ALA
`LA ALA ALA
`SER GlY PHE
`SER GLY PHE
`SER
`GLY PHE
`--�M-::--U�'Oi: b&ICAl �
`asn
`�t� r�� ,�. N"i '"E"' Fri �srii�
`THR .. ,
`PHf
`""
`SER
`PHl l YS SER ASX
`A .. �
`��� ��
`TYR ���
`GLU lYR ASN
`ASX HlS
`SER
`MET
`MET
`HIS
`SER
`TRP
`TRP VAL
`L(U
`AAG GLN GLY PRO GlY
`ARC
`GLN ALA
`PRO CLY
`lYS GlY PRO GLU lRP
`LYS ALA
`lEU
`GLX TAP
`__ SER
`VAL
`VAL
`SER
`THA llE
`ALA ILE.
`THR
`TVR
`TAP
`ASN
`ARG
`GlV
`GLV
`CLY
`GLV
`SER VAL
`THR
`THR
`LEU TVR
`TYR
`TYR
`AV A� SER VAi
`LYS
`GLY
`AAG PHE
`ALA ILE
`SER
`ARr;
`AS» ASH AL4
`GI" L' Tl lE.
`TYR
`LEU
`LEU Gl.N MET ASX
`THR PRO GLU ASP
`Gt.H LEU
`ASH
`MET ASN
`MET
`ASN
`ARG PAO GLU ASP
`ILE
`GlY
`SER
`ASN
`lEU
`ARG
`LEU
`LEU
`
`VAL LEU
`LEU OLN ALA GLU VAL
`ARG ALA
`��· GLX ASX
`At.A GLU ASP
`GLX
`ASX
`THR At.A PHE
`GLV
`THR ALA
`THR ALA
`At.A ALA
`THR THR SER ALA ILE
`GLY
`-:.\sx VAL
`VAL
`VAL
`VAL
`VAL VAL 'TVR
`ARG A5X ARG
`TYR
`TYR TYR
`TYR TYR
`TYR
`TYR TYR
`TYR
`TYR
`TYR TYR
`TYR
`CYS VAL SER
`CVS ALA LY6
`CYS ALA
`CVS ALA
`CVS C'CS CVS ALA
`•
`ALA ALA
`ARG
`ARG
`ARG ARG
`TYR PHE
`GLY TYR
`ASF'
`ASP ALA THRVAL
`
`LEU
`ARG VAL
`SER PAO THR
`ILE
`ALA
`LEU GLY PRO THR
`VAL GLY
`PRO
`At.A ALA
`TRP
`ASH
`SER PRO
`GLY
`THR TYR
`GLY
`CLY
`ALA
`ARG
`SER VAl
`ASH
`LEU
`TAP PHE
`SER·
`CYS
`SER ASP VAL 1RP
`PHE
`VAL
`MET PHE
`ASP ALA
`GLN Gt.V THR LEU
`TRP0 -TAP •
`VAL HIS
`GLY GLV
`GLV
`GlV GLV
`GlN GLN
`Tl<IR THA
`'""G UEU
`SER T'HR THA
`VAL VAL VAL
`
`•
`
`H x
`
`1
`
`... ..
`
`TAP TRP
`VAl VAL VAL
`ARG ARG
`GLN
`
`•
`
`T_
`
`20 21 22 23 2• 2S 211 27 28 29 30 3i 32 33 34 35 36A
`,;168 3e 37 38 ,. "° •1 •2 03 .. 45 06 •7
`
`08
`i
`
`AAG
`PHE
`•LE
`SER
`4RG
`
`I 64 � SI 67 ae .. 70 71 72
`76 77 11: 81 8? ' \: ·..:
`
`t � 16
`
`lYR
`lEU
`GlU At.A GLU
`GlN
`MEI( 95)
`MET
`LEU
`SER
`GLU • ARG
`lEU lEU
`LEU
`PRO ALA
`ALA
`r• '' Gl.U
`·19U
`GLU
`ASP
`ASP
`At.A
`THR
`ALA THR THR THR
`THR
`THR ALA VAL
`ALA At.A ALA
`LEU lEU VAL
`VAL VAL
`VAL
`TYR
`
`TYR TYR TYR TYR
`TYR
`TVR
`TYR TYR
`TVR TYR TVR
`TYR
`TVR
`CYS CYS
`CYS CVS CYS
`ALA ALA
`CYS ALA
`CVS
`At.A ALA ALA
`At.A ARQ
`_,AA,-::::
`ARG ARG LVS
`ARG
`.PHE
`LEU--ASP-GLY
`SER ALA LYS
`ARG
`GlY
`VAL THR ALA PRO TYR ALA
`
`GLH
`SER
`PRO PHE \IAL
`
`ALA
`TYR
`VAL
`VAt
`TYR -
`GUI
`PHE
`
`LVS ASN THR LEU lYR
`
`G :----·--�
`SER !'flO VAi. SIR LfU VAi. ......
`GlY TIW' LfU T'WI TYlll
`w-GL Y GLH
`
`•
`GLY IER VAL
`
`\ \
`
`---
`
`Ql.Y THll
`LEU
`
`SER PRO THR PHE VAl
`
`PHE
`...slJ.�Ep�RT:TMENT °' HEALTH
`r�� -•'7i;tfU'JMAN SEJWICES
`8t� 8t�P�lc l Health *Ice
`�� tfille>Ul lnnstltute� Health
`L YS l.Elll LEU
`LEU
`VAt VAL. VAL
`SER THR THll
`VAL lHR
`
`ASP SE:l
`PHE
`TRP
`GLY GLN
`GLY lYS
`,.._
`GLY
`Gt.Y T'HR THR
`LEU
`VAL
`VAL THR VAL
`THR VAi
`SU
`S£R
`S!=r
`SER
`
`1 of 2
`
`BI Exhibit 1079
`
`

`

`�m11liiiiei'iiili�fi111
`
`3 1822 01003 0666
`SEQUENCES OF
`PROTEINS OF
`IMMUNOLOGICAL
`INTEREST
`
`�
`If:,
`;;/ ,2.93s
`/�??.
`
`- 1/1 _ ,, I
`
`Tabulation and Analysis of
`
`Amino Acid and Nucleic Acid Sequences of
`
`
`Precursors, V-Regions, C-Regions, J-Chain,
`
`
`.62.Microglobulins, Major Histocompatibility Antigens,
`
`
`
`Thy-1, Complement, C-Reactive Protein, Thymopoietin,
`and az-Macroglobulin
`
`1 Post-gamma Globulin,
`
`1983
`
`and Harold Perry"t- JUN q.
`Elvin A Kabat*, Tai Te Wu t, Howard Bilofslfy +, )
`Margaret Reid-Miller+,
`
`1987
`
`• Oepts. of Microbiology,
`
`Human Genetics and Development, and Neurology, Cancer Center/
`
`
`
`
`Institute of Cancer Research, College of Physicians and Surgeons, Columbia University, New
`
`
`
`
`York, NY 10032 and the National Institute of Allergy and Infectious Diseases, Bethesda, MD
`20205
`t Depts. of Biochemistry,
`Molecular Biology, and Cell Biology, and Engineering Sciences and
`
`
`
`
`Applied Mathematics, Northwestern University, Evanston, IL 60201 and the Cancer Center,
`
`
`Northwestern University Medical School, Chicago, IL 60611
`+ Bolt Beranek and
`
`Newman Inc., Cambridge, MA 02238
`
`The collection and maintenance of this data base is sponsored through Contract N01 ·RR-8-2118
`
`
`
`
`
`by the following components of the National Institutes of Health, Bethesda, MO 20205:
`
`Division of Research Resources
`
`National Cancer Institute
`National Institute of Allergy and Infectious Diseases
`
`
`
`
`
`
`National Institute of Arthritis, Diabetes, Digestive and Kidney Diseases
`
`National Institute of General Medical Sciences
`
`U.S. DEPARTMENT OF HEAL TH
`AND HUMAN SERVICES
`
`Public Health Service
`
`National Institutes of Health
`
`(1983)
`
`2 of 2
`
`BI Exhibit 1079
`
`