Fresenius-Kabi USA LLCv. AstraZeneca AB IPR2017-01912
`
`AstraZeneca Exhibit 2044 p.|
`InnoPharmaLicensing LLC v. AstraZeneca AB IPR2017-00905
`
`WWWSININOMLSLGSCOT
`
`

`

`E a
`
`INNOVATIVE RESEARCH OF AMERICA
`PeoeaeeeGSeres
`
`Mostscientists agree that the three essential parameters in the success of a biomedical
`experimentare:
`
`A. The scientific problem formulated in a defined question.
`
`B. The laboratory animal, healthy and untraumatized.
`
`C. The processofactive product delivery; the most problematic variable ofall three!
`
`For a third of a century, Innovative Research of America has assumed the leadership role
`in improved time release technology. The main mission is to standardize the technology of
`drug delivery. Our proven Time Release Hormone and DrugPellets help investigators take
`charge of product delivery and expandtheir abilities to do meaningful and reproducible
`research.
`
`ADVANTAGES OF THE PELLET DELIVERY SYSTEM
`
`
`i
`* a ready-to-administer pelletfor asimple subcutaneous implantation.
`* a convenient long-term controlledproductreleasein laboratoryanimals. _
`« a better method toavoid the“peakand valley” effectsproducedbyconventionaldelivery
`
`
`
`* anew system to extend the productlife againstspontaneous andhost-relatedbreakdown. i
`+ adependable way to minimize theexperimental variables, i Peea
`* a morereliable approach for productive and reproducible research. a
`
`Ushering In The Age OfInnovative Research
`
`AstraZeneca Exhibit 2044 p. 2
`
`

`

`HORMONE AND DRUG PELLETS FOR BIOMEDICAL RESEARCH
`—S_S_——————_—_—_—SSSSSSSSSSSS
`
`Since it is not easy to administer drugs and hormonesorally to research animals,
`several delivery methods have been devised as alternatives. However, most scientists
`continue to labor with unreliable injectables to conduct their research.
`
`Becauseof this inadequacy, biomedical researchis as confusing as it is challenging
`andas frustratingas itis creative. The optionsofscientists to address scientific questions
`are not only dependent, but are also limited by the process of active product delivery.
`Traditionally, product delivery into the experimental animal has been the procedure most
`subject to variables and the most difficult to standardize effectively. The very process
`of having to accurately administer drugs to experimental animals can becomea logistic
`nightmare for scientists.
`
`CHANGING THE TIME COURSE OF DRUG DELIVERY
`
`‘ 183 Wek: a ye
`I minat
`lenk ae
`
`WeTell Time-Release Pellets What Time It Is
`
`Driven.
`ighnotlim
`aie i
`MEA
`eiehgs
`a Laer el }
`
`AstraZeneca Exhibit 2044 p. 3
`
`

`

`|AG TAsce or Contents
`
`Find a Productin this Catalog.......ccccssressccssssceceesssssccseerssseeeennnesseens 5
`Ordering Information / General Policy & Terms............... 6, 7, 44, 84
`Sales of Anabolic Steroids...........cccscccssssesssoscssssescccesccccessesesessscsenenee 8
`
`Placebo Pellets Information/ Price Schedules....................000
`
`Alphabetical Product LISting............:.scccesseeeeeeeeecseeeseeseeesseaceees 21-42
`Stock Pellet Price SCHEGUICS...........:00sssssscccesccscccssessessonsessssssseee 45-71
`
`Pellets for Immuno-Deficient Mice
`
`17B8-Estradiol / Tamoxifen & Sample References.................. 73-77
`Androgens/ Anti-Androgens & Sample References............... 78-80
`Trochar & Recommended Implantation Procedure............... 81,123
`Doxycycline & Tetracycline Pellets in Mice............::c:scseeeeeeeeees 85-86
`Hormone + Hormone Pellets .........ccccccssssssscecsccccccceeeeseeesseeeeeeeees 89-92
`
`CUO PGE sca seiicasbicsonanvecscdcsans sssttsesaaesereacesstaaaeseatecanetiiaensés 93-108
`
`Selected References................::cccesccsssseeeseeceeeeeeeccceeeeeeseesneeeees 109-122
`
`Ort POIIIG oss ssssccnisnsveresscnsceteisscssaasssessersssssiastsnsnerae Backof Catalog
`
`POROTNG os sssssssiscsesecesssisvanaccossesaccscecaesseeesnsicasassnindeecaze Inside Back Cover
`
`CARSONY WNIGKcaissisessscesechecaveccecsciicesredaabasarazensntassasnisesgnataensneete 10-15
`Alkaloids
`Estrogens
`Amino Acids
`Fatty Acids
`Androgens
`Nucleotide Related Products
`Antibiotics
`Progestins
`Anti-Inflammatory Agents
`Prostaglandins
`Anti-Neoplastics
`Thyroids
`Catecholamines
`Vitamins
`Corticoids and Diuretics
`
`We Add Time To Your Day
`
`*Forfurther assistance, view our website at:
`www.innovrsrch.com
`
`AstraZeneca Exhibit 2044 p. 4
`
`

`

`PRODUCT DESIGN AND FEATURES
`
`aes oy
`
`ae
`eA
`
`The Pellet Implantation Methodology provides solutions to:
`
`.. consistency in timing repeated product administrations.
`
`... controlling the amount of product administered.
`
`.. Stability of the productpreparation.
`
`.. Safety of the experimenter,
`
`.. heurophysiological traumato the animal from excessive handling.
`
`.. freeing valuable research time.
`
`... ¢liminating unnecessary and unstimulating laboratory practices.
`
`Scientists from several research disciplines have documented in scientific literature that
`our Pellet Delivery System is effective, consistent, reproducible, economical, reliable, and
`safe for the animal. See Selected References on pages 109-122.
`
`Only TimeRelease Pellets Really Know What Time It Is
`
`AstraZeneca Exhibit 2044 p. 5
`
`

`

`PRODUCT SPECIFICATIONS
`
`AVAILABLE SHAPES AND SIZES
`
`Stock pellets are round and range in diameter from 1/8” (3 mm) to 1/2” (1.25 cm) depending on the
`dose and the release rate. Our Custom Pellets Department will also design various pellet shapes and
`smaller sizes (Page 94) to meet your research needs. Please refer to the Custom Pellets section on pages
`93-108.
`
`AVAILABLE DOSAGES
`
`Mostof the stock productsin this catalog are available in 20 different dosages ranging from | microgram
`(0.001 mg) per pellet up to 200 milligrams (200 mg) per pellet within the specified release rate. Doses of
`pellets listed in this catalog reflect the total amount of net active product released over the indicated
`period oftime.
`
`AVAILABLE RELEASE RATES
`
`Stock products are designed to release continuously for 21 days, 60 days, or 90 days. Please refer to our
`Custom Pellets section on pages 93-108 for other release rates tailored for the duration of the experiment.
`
`AVAILABLE PRODUCTS
`
`In our continuing quest to make available new stock items that are particularly in demand, we have added
`several products to the original categories. In addition to the listed pelletized products, Innovative
`Research of America has an efficient Custom Pellets Departmentto prepare products that are not available
`as stock items.
`
`SELECTED REFERENCES
`
`A sample of publications that employed our delivery system in a broad spectrum of products can be found
`on pages 109-122.
`
`Consistent Dose-DependentRelease
`
`AstraZeneca Exhibit 2044 p. 6
`
`

`

`FINDING A PRODUCTIN THIS CATALOG
`————neeS
`
`The PRODUCTSin this catalog are arranged in ALPHABETICAL ORDERandareidentified by
`a CATALOG NUMBERand a PRICE SCHEDULEwith a PAGE NUMBER.
`The catalog numberandprice schedule reflect a release rate of 21 days, 60 days, or 90 days.
`To illustrate with 178-Estradiol as an example:
`
`EXAMPLE
`
`90-Day Release
`60-Day Release
`21-Day Release
`Product
`
`Catalog——Price Schedule/ Catalog Price Schedule/ Catalog Price Schedule/
`
`
`
`Number
`Page Number
`Number
`Page Number
`Number
`Page Number
`
`
`
`178 - Estradiol
`
`E- 12)
`
`B-21/48
`
`SE- 12]
`
`B-60/49
`
`NE - 121
`
`B-90/50
`
`The above example indicates that 176-Estradiol is available in three release forms each having a
`different catalog numberandprice code, i.e.
`
`E - 121 is a 21-day release form with a price code of B-21, found on page 48.
`SE - 121 is a 60-day release form with a price code of B-60, found on page 49.
`NE - 121 is a 90-day release form with a price code of B-90, found on page 50.
`
`|
`
`The PAGE NUMBERnextto the PRICE SCHEDULEindicates the page where the actual price
`for the product appears.
`
`When ordering please use the PRODUCT NAME, CATALOG NUMBER, RELEASE
`RATE and DOSE.Most productsare available in 20 different dosages. Products are sold in
`Lots of 25, 50, 100, and 200 pellets. Please indicate the quantity of pellets being ordered.
`
`Beginning on Page 10 we have grouped someofour catalog items in related categories
`alphabetically. We hopethelisting will help in noting items ofpotential interest.
`
`Time-Release Pellets...Always On Time
`
`AstraZeneca Exhibit 2044 p. 7
`
`

`

`
`
`
`
`¢ Mail
`Innovative Research of America, Inc.
`2 North Tamiami Trail
`Suite 404
`Sarasota, Florida 34236 USA
`
`¢ Internet / E-Mail
`http://www.innovrsrch.com (website)
`pellets@innoyrsrch.com (e-mail)
`
`IRA’s website features our companyprofile,
`the latest product technology and on-line ordering.
`
`* Phone
`(941) 365-1406
`(941) 365-1506
`(800) 421-8171 (USA/Canada)
`
`
`
`SS catalog.
`
`f) AMERICAN EXPRESS,
`VISAAND MASTERCARD ACCEPTED.
`* Fax
`’visa’_| Purchase Order Formsare in the backof the
`(941) 365-1703
`(941) 365-1803
`(800) 643-4345 (USA/Canada)
`(800) 648-6030 (USA/Canada)
`
`Custom Pellets Information Form on page 95.
`
`Bank Wire Payment Information
`Payment via bank wire should be directed as follows:
`
`THE DIFFERENCE IS
`
`CONSISTENCY AND UNIFORMITY,
`
`BB&T Bank
`
`1800 Second SL, Suite 100
`Sarasota, Florida 34236
`Routing # (ABA) 263191387
`Electronic Transfers # 263191387
`
`In favor of:
`Innovative Research of America
`
`2 North Tamiami Trail
`Suite 404
`
`Sarasota, FL 34236
`
`Checking Account: #0000147816154
`Swift Code: BRBTUS33
`
`Ushering In The AgeOfInnovative Research
`
`AstraZeneca Exhibit 2044 p. 8
`
`

`

`GENERAL POLICY AND TERMS
`eREEEeeeeSE
`
`POLICY
`
`navia
`
`
`
`
`
`
`
`AstraZeneca Exhibit 2044 p. 9
`
`

`

`SALE OF CONTROLLED ANABOLIC STEROIDS
`within the United States
`
`(Telephone orders will not be accepted - orders & copy of DEA license may be mailed or faxed)
`
`Before we can prepare any orders of Anabolic Steroid Pellets, the Drug
`Enforcement Administration (DEA) requires us to obtain:
`1. A valid photocopy ofthe investigator’s DEA Registration
`containing Schedule 3N.
`2. A written Purchase Order showing the investigator’s DEA
`Registration Number and proper shipping address.
`
`CONTACT INNOVATIVE RESEARCH OF AMERICA
`
`BY PHONE, MAIL, FAX OR E-MAIL
`
`FOR MORE ORDERING INFORMATION - SEE PAGE 6
`
`SALE OF CONTROLLED ANABOLIC STEROIDS
`outside the United States (International)
`aa
`
`WE NO LONGERSHIP ANABOLIC STEROIDS
`
`outside the United States (International)
`
`DEA Controlled Anabolic Steroids
`
`Androstenediol
`
`19-Nortestosterone 17-Decanoate
`
`Androstenedione
`5a-Dihydrotestosterone
`Fluoxymesterone
`
`Mesterolone
`
`Mesterone
`
`Methandriol
`Methandriol Dipropionate
`19-Nortestosterone
`
`19-Nortestosterone 17-Dipropionate
`Stanozolol
`Testosterone
`
`Testosterone Acetate
`
`Testosterone Benzoate
`
`Testosterone Cypionate
`Testosterone Enanthate
`Testosterone 17&-Hemisuccinate
`
`7
`
`Time Release Pellets ...Always On Time
`
`Testosterone Propionate
`
`AstraZeneca Exhibit 2044 p. 10
`
`

`

`Ad
`
`—_a
`
`See pages 73-80 regarding
`Hormone/Anti-Hormone products
`for Immuno-Deficient Mice
`and specific references.
`
`Your Research Time Is UnderYour Control
`
`AstraZeneca Exhibit 2044p. 11
`
`

`

`CATEGORY INDEX
`
`|
`
`Onthe following 6 pages, we have grouped some of our Catalog itemsin related categories.
`Hopefully this listing will help in noting items of potential interest.
`
`ALKAL I
`
`10
`
`AstraZeneca Exhibit 2044 p. 12
`
`

`

`We AddALittle Time To Your Day AstraZeneca Exhibit 2044 p. 13
`
`ANTI-INFLAMMATORYAGENTS
`
`

`

` CATECHOLAMINES AND RELATED PRODUCTS
`
`12 AstraZeneca Exhibit 2044 p. 14
`
`
`
`[t’s Time For Clear, Consistent Results
`
`

`

`CORTICOIDS AN
`
`CATEGORY INDEX (continued)
`
`WhenReliability Counts AstraZeneca Exhibit 2044 p. 15
`
`

`

`CATEGORY INDEX (continued)
`
`Use Time To Your Advantage
`
`“Pregnenolone.
`a“Progesterone
`
`AstraZeneca Exhibit 2044 p. 16
`
`

`

`CATEGORY INDEX continues)
`
`Consistent Results With Consistent Release
`
`jrocholesterol (ProvitaminD,)
`sterol (Provitamin D) ~
`
`eee
`eS
`amin
`
`VitaminK;(Menadione)=alee)
`
`AstraZeneca Exhibit 2044 p. 17
`
`

`

`|
`ADVANTAGES OF OUR MDD PELLET SYSTEM |
`
`+ Saves time
`
`« Ready-to-implant
`
`«
`
`Insures controlled product release over time
`
`« Avoids “peak and valley” effects
`
`« Guarantees consistent product preparation
`
`« Extends productlife against spontaneous breakdown
`
`« Extends productlife against host-related breakdown
`
`¢ Minimizes experimental variables
`
`«
`
`Insures safety of the researcher
`
`« Reduces neurophysiological trauma to the animal/
`
`no.~ ‘cessive handling
`
`« Generates more meaningful and reproducible results
`
`¢ Superior to conventional delivery methods
`
`« Enhances experimental efficiency
`
`« Frees valuable time for creative research
`
`« Saves money
`
`
`
`AstraZeneca Exhibit 2044 p. 18
`
`

`

`zz
`
`
`
`PLACEBO / CONTROL
`PELLETS
`
`
`Matching Placebopellets contain all the components of the hormone or drug pellet except the active
`productitself. The carrier-binder excepients of the matrix include Cholesterol, Lactose, Celluloses,
`Phosphates and Stearates.
`
`Stock Placebo pellets are available in 20 different doses corresponding to those of active product
`pellets. Each dose is offered in either 21 Day, 60 Day, or 90 Day Release form.
`
`Although the matrixes in Placebo pellets have a different composition for different active products,
`they are all assigned the same catalog numberand are offered at the same price schedule.
`
`Wheninquiring or placing an order, please specify the active product you wish to correspond the
`Placebo pellets for. Please see the following examples:
`
`Ore rea tie
`
`TTT sl eco
`
`Dose in mg/pellet
`
`Release in Days
`
`Placebo for “Active Product”*
`
`mg/pellet
`
`21 Day
`
`C-111
`
`SC-111
`
`60 Day NC-111
`
`Placebo for “Active Product’’*
`
`Placebo for “Active Product”*
`
`mg/pellet
`
`mg/pellet
`
`90 Day
`
`
`
`
`*In place of “Active Product” specify the hormoneor drug youareutilizing in your study.
`
`The following three pages are universal dose /price schedules in all three release rates (21 Day, 60
`Day, and 90 Day) and are applicable as a matching Placebo for all productsin the catalog except
`special physical size and preparations (page 94) which can be found under the Custom Pellet section
`on pages 93-108.
`
`*Please inquire directlywith usiffurther assistance is required regarding a productofinterest.
`
`
`
`DEE RT Sct dork
`; |TaveboPelletsPorProper|a
`
`eaeee
`
`ae
`
`AstraZeneca Exhibit 2044 p. 19
`
`

`

`AstraZeneca Exhibit 2044 p. 20
`
`
`

`

`___PLACEBO PELLETS.
`
`
`
`PRICE SCHEDULE
`
`Cat. No, C-111
`
`
`
`
`
`
`
`
`
`
`
`Bone oe vellet
`pe
` 1ee
`vpel
`0.004
`$697
`$1362
`$2649
`$4816
`0.010
`$697
`$1362
`2649
`94816
`0,025
`u697
`1362
`$2649
`04816
`0.05
`S697
`$1362
`$2649
`34816
`0.1
`$697
`$1362
`$2649
`$4916
`0.25
`£697
`$1362
`22646
`$4816
`0.5
`$697
`$1362
`$2649
`$481
`15
`£697
`$1362
`$2649
`34816
`25
`S697
`P1362
`52649
`24816
`5.0
`$697
`$1362
`32649
`4016
`fee
`$702
`$1379
`2674
`$4855
`10.0
`#702
`$1379
`$2674
`$4658
`
`15.0
`E702
`01379
`52674
`04858
`25.0
`$707
`51386
`92674
`$4875
`35.0
`3107
`$1386
`$2674
`$4075
`50.0
`SfOF
`$1386
`$2674
`$4875
`15.0
`9/07
`$1386
`$2674
`$4875
`
`100.0
`$718
`$1406
`$2734
`$4945
`150.0
`$718
`$1406
`$2734
`$4946
`
`o2/744
`$4964
`A combination of multiple dosagesin onelot, for any specified product,is also
`available. PLEASE INQUIRE.
`
`|
`
`
`
`
`
`Sixty and Ninety day price schedules are on the following two pages.
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`17
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
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`
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`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`AstraZeneca Exhibit 2044 p. 21
`
`
`
`

`

`
`
`PRICE SCHEDULE
`
`
`Cat. No. SC-11]
`
`0.010
`
`0.025
`
`0.05
`
`0.4
`
`
`
`0.25
`
`0.8
`
`Ls
`
`2.9
`
`9.0
`
`TS
`
`100.0
`
`
`
`
`
`
`
`
`
`
`$2751
`$2751
`$731
`$731
`$2751
`$2751
`$731
`$2761
`$731
`$2751
`$731
`$2751
`$731
`$731
`$2751
`S4074
`$4974
`$734
`$2751
`4974
`$2751
`$731
`$5038
`$738
`$2789
`$5038
`$738
`$2789
`$5038
`$2789
`$1444
`$738
`
`$5063
`$1454
`$744
`$2804
`$744
`$2804
`$1454
`$0063
`$2804
`$744
`$5063
`$1454
`$744
`$5063
`$2804
`$1454
`$5168
`$762
`$2879
`$1484.
`$2879
`$5168
`$1484
`$762
`150.0
`
`$1498
`$2894
`S5197
`A combination of multiple dosages in onelot, for any specified product, is also
`available. PLEASE INQUIRE.
`
`04974
`4974
`54974
`$4974
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`10.0
`
`15.0
`
`25.0
`
`35.0
`
`90.0
`
`75.0
`
`
`AstraZeneca Exhibit 2044 p. 22
`
`

`

`
`
`
`
`
`ta | 3 Viera ewanCFraheeeee Ue ge SMe ace |
`
`
`
`
`available. PLEASE INQUIRE.
`
`PRICE SCHEDULE
`
`NC-111
`Cat. No.
`fi ETY. AY. 5 RE , HA. Ren
`
`Tiss
`
`Aae a Ly Eyape pA hee BUT
`
`f
`
`A combination of multiple dosages in one lot, for any specified product, is also
`
`AstraZeneca Exhibit 2044 p. 23
`
`

`

`BIOMEDICAL RESEARCH IN
`
`
`One-Step Continuous ReleasePellets Are the Best Alternative
`
`Time Release Pellets
`for Biomedical Research from IRA
`DOSE
`
`OM
`yyw»
`
`
`
`
` TIME RELEASE PELLETS FoR
`
`LABORATORY ANIMALS
`Multi-StepInjectionsAreaContinuous Pain in DRUG DELIVERY
`
`RELEASE Day1
`
`
`Day 2
`
`
`
`Our Team at IRA is working
`FOR
`to meet the responsibility that
`"
`
`Innovative Science demands
`T ie ie ¢ esa i vd 3
`and Innovative Scientists
`4 3 S 7 # ed ‘eS
`
`se
`
`a ee
`
` deserve.
`
`
`
`AstraZeneca Exhibit 2044 p. 24
`
`

`

`RA INTRODUCTION TO
`
`ALPHABETICAL PropuctT LISTING
`
`The PRODUCT NAMES in this catalog are arranged in ALPHABETICAL
`ORDER and are identified by their individual CATALOG NUMBERSincluding a
`PRICE SCHEDULEand corresponding PAGE NUMBER.The catalog number and
`eSKee RoaOCA ee ON
`
`Toillustrate with Acetazolamide as an example, please viewthe following table:
`
`Product Name
`
`21 DayRelease
`
`UB Esco (ots
`
`90 Day Release
`
`Acetazolamide
`
`Catalog
`Number
`D-111
`
`Price Schedule/
`Page Number
`C21/51
`
`Catalog
`Number
`SD-111
`
`Price Schedule/
`Page Number
`C60 / 52
`
`Catalog
`Number
`ND-111
`
`Price Schedule/
`Page Number
`C90 /53
`
`IEDativeWaeletay
`
`When placing an order, please include the PRODUCT NAME, CATALOG NUMBER, DOSEIN
`MG/PELLET and RELEASE RATE.Mostof our products are available in 20 different doses.
`Products are normallysoldin lots of 25, 50, 100, and 200 pellets. Please indicate the quantity
`ofpellets to be ordered.
`Beginning on page 10, we have grouped some of our catalog items by related categories
`alphabetically. We hopethe listing will help in noting items of potential interest.
`
`The above exampleindicates the stock product Acetazolamideis available in three release
`forms each having a different catalog numberand price code,i.e.
`
`SOR Me eed PENA teMeme)OPA Mm CITGO)Meretoced
`SD-111 is a 60 Day Release form with a price code of C-60, found on page 52.
`ND-111 is a 90 Day Release form with a price code of C-90, found on page 53.
`
`The PAGE NUMBER nextto the PRICE SCHEDULE indicates the page where the actual
`pricefor the product appears.
`
`*Please inquire directly with usiffurtherassistance is required regarding a productofinterest.
`
`AstraZeneca Exhibit 2044 p. 25
`
`

`

`
`
`AstraZeneca Exhibit 2044 p. 26
`
`

`

`ALPHABETICAL PRODUCT LISTING
`Ss
`Dose/Price Schedules For Matching Placebo Pellets Appear On Pages 17-19.
`
`21-Day Release|60-Day Release|90-Day Release
`
`
`i Catalog Price Schedole/|Catalog Price Schedule/ Catalog Price Schedule/
`iigutelicul
`Number Page Number
`Number Page Number
`Number Page Number
`
`
`
`
`
`
`
`Acebutolol B-21/48|SC-101 B-60/49|NC-101: B-90/50
`
`
`
`Ae i : ie 02, ; -A21/45. SA102- 60/46 A ! e 0 } é 90/47
`he 3-Acetamidofluorene(2:AAr)
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`
`
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`
`
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`| o ei ‘ eara 3$0.a1 =C60[52 No S
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`me 2 pe B-21/48- “SV272 iB-60/49|NV272.
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`
`
`
`_N-Acety/--Cysteine B-21/48|$Q-212- B-60/49
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`i HM B21148 l$a:272 : : B-60/49 t 027 2°B-90/50
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`
`
`ie N-Acetylimidazole B-21/48|SQ-273- B-60/49
`N Acetylprocainamide |
`Get
`: A21/45|SC-106- (N-60/46- | ct 6AA-90/4fi
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`
`
`
`
`cis-Aconitic Acid B-21/48|SK-111; B-60/49 B-90/50
`
`
`
`
`
`FPtrans:Aconitic Acid
`
`i112
`
`C-2ti51 | SK-t12
`
` C-60/52 | NK-12 C-90/53
`
`
`
`
`
`
`
`Aconitine E-21/57|}SK-113 E-60/58|NK-- E-90/59
`
`
`
`AGinomycin D (Dactinomycin)
`
`-
`
`H-24/60 ~$Z-110
`
`_H-60/61 : NZ. 1
`
`‘ -H-90/62
`
`D-90/56
`
`
`
`
`
`
`
`
`
`Adenosine C-21/51|SN-111- C-60/52 - C-90/53
`
`
`
`se-t16 B-60/49 | NG-116 _B.90/50
`|-G1e B-21/48|
`BAarenalCortex Acetone Powder
`
`
`
`
`Adrenosterone B-21/48|SG-117 B-60/49|NG-117: B-90/50
`
`) H-21/60|$Z-180 H-60/61. NZ-180.H-90/62
`
`
`
`
`
`B-21/48|SC-135 B-60/49|NC-135 B-90/50
`
`
`
`
`
`B-21/48|SQ-111 B-60/49|NQ-111 —B-90/50
`
`C-21/51 | SQ-121
`
`C-60/52'| NQ-121 C-90/53
`
`c-21/51| sa-131 C-60/62| NQ-131 C9053
`
`
`
`
`
`B-21148|SB-166 B-60/49|NB-166 B-90/50
`
`H-21/60|
`
`SM-161
`
`H-60/61 |NM-151 H90/62
`
`
`
`
`
`B-21/48|SI-111 B-60/49|NI-111 —B-90/50
`
`60/46 | NA-103° A-90/47.
`SA+103
`A-21/45|
`[oxen
`
`
`Alprenolo! D-21/54|SC-431 D-60/55|NC-431“
`
`
`
`21
`
`AstraZeneca Exhibit 2044 p. 27
`
`

`

`|
`ALPHABETICAL PRODUCT LISTING __
`
`21-Day Release|60-Day Release|90-Day Release
`
`Catalog Price Schedule/|Catalog Price Schedule/ Catalog Price Schedule/
`Product
`Number Page Number
`Number Page Number
`Number Page Number
`
`
`
`
`Althiazide B-21/48|SA-104 B-60/49|NA-104 B-90/50
`
`
`
`
`_ Amantadine B-21/48|SB-167 B-60/49|NB-167| B-90/50
`
`
`
`Ameinonide A-21/45|SG-118 A-60/46|NG-118 A-90/47
`
`Amiloride B-60/49|ND-181| B-21/48| SD-181 B-90/50
`
`
`
`
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`
`
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`Aminicacetonitille B-21/48|SA-105 B-60/49|NA-105| B-90/50
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`
`
`
`o-Aminoacetophenone “A-21/45|SA-106 A-60/46.|NA-106iN A-90/47
`
`
`
`m-Aminoacetophenone B-21/48|SA-107 6B-60/49|NA-107 8B-90/50
`
`
`
`p-Aminoacetophenone B+21/48|SA-108 B-60/49|NA-108 B-90/50
`
`
`
`
`
`Aminoglutethimide D-60/55|NG-281D-21/54| SG-281 D-90/56
`
`
`
`A-90/47
`
`
`
`
`_ 6-AminopenicillanicAcid B-21/48|SB-111 B-60/49|NB-111| B-90/50
`
`
`
`
`
`
`
`
`Aminophylline | -60/52|NC-125C-21/51| SC-125 C-90/53
`
`
`
`ae Aminopyrine i B-21/48|SA-109 B-60/49|NA-109 B-90/50
`
`
`
`Amiodarane B-21/48|SA-112 B-60/49|NA-112 8B-90/50
`
`
`
`
`
`Amitriptyline = €-60/52|NC-451| €-21/51| SC-451 C-90/53
`
`
`
`Amoxicilin B-21/48|SB-112 B-60/49|NB-112 B-90/50
`
`
`
`
`; _Amphotericin Bee D-60/55|NB-113D-21/54| SB-113 D-90/56
`
`
`
`Amptcilin B-21/48|SB-114 B-60/49|NB-114 —_B-90/50
`
`
`
`
`“Amine 60/46|NC-107eal -A-24/45 | SC-107 A-90/47
`
`
`
`
`Androstenediol B-21/48|SA-131 B-60/49|NA-131(Seeconoted Subsences Page 8 B-90/50
`
`_ Androstenedione(seeconroedsissancosrones)| A121 B-21/48|SA-121 B-60/49 | NA-121 B-90/50
`
`
`
`
`
`Sa-Androsterone if C-60/52|NA-141c-21/51| SA-141 C-90/53
`
`
`—SRAndrosterone =si(si(‘“(t;*‘;~*é* A:T] SA-101 D-60IS5|NA-101 D-90/56
`
`
`
`
`
`~ Anisodamine B-60/49|NK-114) ~B-21/48| SK-114 —B-90/50
`
`ErAnisodine! eon ee | NK-115—B-90/50- B-21/48| SK-115 B-60/49 |
`
`
`
`
`
`
`
`‘Antazoline C-6052|NC-461| c-21/51| Sc-461 C-90/53
`
`
`
`
`| ArachidicAcid = ? A-21/45|SF-111 A-60/46|NF-111| A-90/47
`
`
`
`
`
`ArachidonicAcid A-21/45|SF-161 A-60/46|NF-161
`
`22
`
`AstraZeneca Exhibit 2044p. 28
`
`

`

`ALPHABETICAL PRODUCT LISTING
`Ce
`Dose/Price Schedules For Matching Placebo Pellets Appear On Pages 17-19.
`
`21-Day Release|60-Day Release|90-Day Release
`
`> Catalog Price Sechedule/|Catalog Price Schedule/ Catalog Price Schedule/
`
`
`igitita!
`Number Page Number Sr emmy Nray TemTTog
`
`
`
`
`
`
`
`
`
`C-60/52|NK-119 C-90/53
`
`
`
`Arecoline C-60/52|NK-116. C-21/51| SK-116 C-90/53
`
`| 441 B2148 | sa141 B-6049 |NO-141B-90/50
` D-Arginne
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`c-2151|
`sa1s1
`c-60/52 | NO151
`C-90/53
`"L-Arginine
`ee 2 i H-21/60 -$Z-120 H-60/61 | NZ-120. H-90/62
`* Asparaginase
`" DeAsparagine c-60/52|NQ-161 C-90/53461 c-21/51] sa-161
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`
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`"LeAsparagine
`atm casi| sat7i
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`"DeAspartic Acid ¢-60/52|NO-181 C-90/53c-21/51|} sa-181
`
`
`
`©Laspartic Acid
`21/51] Sa-191 C-6052 | NO-191 C-90/53
`491
`
`
`
`
`“Aspirin C-21/51|SX-121 C-60/52|NX-1213 C-90/53
`
`Atenolol B-60/49|Ne-221 B-90/50B.21/48 | Sc-221
`
`"Atropine
`c-21/51|
`sK-117
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`C-60/52 | NK-117
`C-90/53
`
`
`
`(>Atropine Methyl Bromide C-60/52|NK-118C-21/51| SK-118 C-90/53
`
`
`
`" BeAzaadenine B-21/48|SN-121 B-60/49|NN-121 B-90/50
`
`
`
`|5-Azacytidine A-21/45|SN-131 A-60/46|NN-131: A-90/47
`" -BeAzaoyiosing
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`c-21/51|
`SN-141
`c-60/52 | NN-141
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`>B-Azaguanine
`C-21/51|
`SN-151
`C-60/52] NN-151
` C-90/53
`
`
`
`_ &-Azahypoxanthine C-21/51|SN-161 C-60/52|NN-161 C-90/53
`
`
`
`Be: B-21/48|SN-171 B-60/49|NN-171 B-90/50
`
`
`
`
`
`B-21/48|SN-181 B-60/49|NN-181 B-90/50
`
`B-21/48 | SN-191 B-60/49|NN-191 B-90/50
`
`
`
`
`
`c-2151] ¢-60/52|NN-201SN-201 C-90/53
`B-21/48 |
`SN-211
`B-60/49 | NN-211 B-90/50
`
`
`Bacitracin B-21/48|SB-115 6B-60/49|NB-115- B-90/50
`
`
`
`
`
`‘Baclofen A-21/45|SB-110 A-60/46|NB-110 —A-90/47B
`
`D-21/54| SB-116 D-6055|NB-116 D-90/56
`pe Benzyip D-60/55|NB-117_D-90/56D-21/54| SB-117
`
`
`
`Berberine
`c-21/51|
`sk-119
`
`23
`
`AstraZeneca Exhibit 2044 p. 29
`
`

`

`ALPHABETICAL PRODUCT LISTING
`
`,
`
`21-Day Release|60-Day Release|90-Day Release
`
`/ Catalog Price Schedule/|Catalog Price Schedule/|Catalog Price Schedule/5
`
`
`Product
`Number Page Number
`Number Page Number
`Number Page Number
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`
`
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`
`
`
`Betamethasone L-21/63|SG-191 L-60/64|NG-191G-191 L-90/65
`
`
`
`
`
`
`
`Boldine C-21/51|SK-120 C-60/52|NK-120—§C-90/53K-120
`
`
`
`
`
`8-Bromoadenosine 3':5' Cyclic Monophosphate|N-221 M-21/66|SN-221 M-60-67|NN-221 M-90/68
`
`
`
`
`Bromocriptine Mesylate E-21/57|SC-231 £-60/58|NC-231C-231 ~E-90/59
`
`
`
`
`
`
`
`5-Bromo-2'-Deoxyuridine (BrDU) B-21/48|SN-231 B-60/49|NN-231N-231 B-90/50
`
`
`
`Brucine C-60/52|NK-122K-122 C-21/51} SK-122 C-90/53
`
`
`
`
`
`
`
`
`
`Busulfan (Myleran) B-21/48|SZ-130 B-60/49|NZ-1302-130 B-90/50
`
`
`
`Caffeine C-60/52|NC-191C-191 C-21/51.| SC-191 C-90/53
`
`C-90/53 Cephalexin
`
`
`
`
`
`
`
`
`
`
`
`
`
`Calycanthine B-21/48|SK-123 B-60/49|NK-123K-123 B-90/50
`
`
`
`
`Camptothecin E-21/57|SC-116 &-60/58|NC-116C-116 E-90/59. !
`
`
`
`
`
`Captopril B-21/48|SC-117 B-60/49|NC-117C-117 B-90/50
`
`
`
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`
`‘Carbamazepine C-21/51}SC-113 C-60/52|NC-113C-113 C-90/53
`
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`
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`
`
`Carbinoxamine C-21/51|SC-471. C-60/52|NC-471C-471 C-90/53
`
`
`
`
`DL-Carnitine C-21/51|SV-271 C-60/52|NV-271V-271 C-90/53
`
`
`
`
`&-Carotene C-21/51|SV-215 C-60/52|NV-215V-215 C-90/53
`
`Casodex(bicalutamide) a
`
`:
`
`We can custom make any dose and any release time. (PLEASE /NQUIRE)
`
`
`
`
`
`Cefadroxil A-21/45|SB-170 A-60/46|NB-170B-170 A-90/47
`
`
`
`
`
`| Cefamandole. — A-60/46|NB-171B-171 A-21/45.| SB-171 A-90/47
`
`Cefazolin A-21/45|SB-172 A-60/46|NB-172B-172 A-90/47
`
`
`
`
`
`
`
`
`
`- Cefmetazole 2 A-60/46|NB-173. A-90/47.B73 A-21/45.| SB-173
`
`
`
`
`
`
`
`
`Cefoperazone A-21/45|SB-174 A-60/46|NB-174B-174 A-90/47
`
`
`
`
`
`= Cefotaxime A-21/45|SB-175 A-60/46|NB-175os B-175 A-90/47
`
`
`
`
`
`Cefoxitin A-21/45|SB-176 A-60/46|NB-176B-176 A-90/47
`
`
`
`
`Cefsulodin A-21/45|SB-177 A-60/46|NB-177.. A-90/47| B+4177
`
`
`
`
`
`
`
`Ceftriaxone A-21/45|SB-178 A-60/46|NB-178B-178 A-90/47
`
`
`
`
`
`
`
`Centrophenoxine (Meclofenoxate) C-21/51|SC-115 C-60/52|NC-115C-115
`
`
`
`
`
`
`
`
`
`B-118 B-21/48|SB-118 B-60/49|NB-118 B-90/50
`
`24
`
`AstraZeneca Exhibit 2044 p. 30
`
`

`

`i ALPHABETICAL PRODUCT LISTINGaaAIiRE
`
`Dose/Price Schedules For Matching Placebo Pellets Appear On Pages 17-19.
`
`21-Day Release|60-Day Release|90-Day Release
`Catalog Price Schedule/|Catalog Price Schedule/|Catalog Price Schedule/
`Product
`entag Page Number
`Number Page Number
`Number Page Number
`
`Cephalogiycin D-60/55|NB-119B-119 D-21/54| SB-119 D-90/56
`
`
`
`
`
`|Cephalothin
`oboe21/48 $B-120B-60/49“NB-120©B-90/50.
`ei
`
`
`
`
`Cephapirin 8.21/48|sB-121 B-60/49|NB-121B21 B-90/50
`
`“Chloramphenicol C-21/51|SX-131 C-60/52|NX-131X-131 C-90/53
`
`
`
`
`ie=Chloramphenicol Base
`. Bog" =) C-21/51. “$B-123. C-60/52 /NB-123 C-90/53
`
`
`
`
`
`Chlorcyclizine B-21/48|SC-145 B-60/49|NC-145C-145 B-90/50
`=Chlormadinone Acetate
`221 A-21/45 |$P-221
`60/46 |NP-221. A-90/47.
`
`
`
`
`
`Chloroquine C-60/52|NI-12L112 C-21/51] S112 —C-90/53
`FPChlorothiazide
`C155
`C-21/51| Sc-155
`C-60/52| NC-155 C-90/53
`
`
`
`
`
`
`
`
`
`B-90/50
`
`
`
`Chiorotrianisene C-60/52|NE-201E-201 C-21/51| SE-201 C-90/53
`
`
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`
`
`BPChiorpheniramine C-21/51|SB-124| B124 C-60/52 | NB-124 C-90/53
`
`
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`
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`Chlorpromazine C-21/51|SC-241 C-60/52|NC-241C-241 C-90/53
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`
`
`ffChlorthalidone _B-21/48|SC-175 B-60/49|NC-175 B:90/50C175
`
`
`
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`
`
`Chlorzoxazone C-21/51|SC-185 C-60/52|NC-185C-185 C-90/53
`
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`Cimetidine B.21/48|SC-372 B-60/49|NC-372C-372. B-90/50
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`
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`
`
`
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`
`
`Cinchonidine C-21/51|SB-154 C-60/52|NB-154B-154 C-90/53
`
`
`bcinnarizine C-21/51|SB-125B-125 C-60/52 | NB+125 C-90/53,
`
`
`
`
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`
`
`Clemastine B-21/48|SC-120 B-60/49|NC-120C-120 B-90/50
`
`
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`
`:iClemizole c-60/52|NC-119C-119 C-21/51| Sc-119 C-90/53
`
`
`
`
`‘Clenbuterol -H-21/60|SC-118 H-60/61|NC-118C-118 H-90/62
`
`
`EClofoctol -C-21/51|SC-104 C-60/52|NC-104 -C-90/53C-104-
`
`
`
`
`
`ClomipheneCitrate B-21/48|SP-211 B-60/49|NP-211P-211 B-90/50
`
`
`
`
`Eeiomipramine ¢-21/51|}'sc-103 ¢-60/52|NC-103C103 C-90/53
`
`
`
`
`
`
`
`Clonidine B-21/48|SC-251 B-60/49|NC-251C-251 B-90/50
`
`
`
`
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`
`
`Glopamide _B-21/48|SC-105C-105 —B-60/49 NC-105, B-90/50.
`
`
`
`
`
`
`
`
`
`Clotrimazole B-21/48|SB-126 B-60/49|NB-126B-126
`
`
`
`25
`
`AstraZeneca Exhibit 2044 p. 31
`
`

`

`ALPHABETICAL PRODUCT LISTING
`
`Dose/Price Schedules For Matching Placebo Pellets Appear On Pages 17-19.
`
`21-Day Release|60-Day Release|90-Day Release
`
`Catalog Price Schedule/|Catalog Price Schedule/ Catalog Price Schedule/
`Product
`Number Page Number
`Number Page Number
`Number Page Number
`
`
`
`
`
`
`
`Cloxacillin B-21/48|SB-127 B-60/49|NB-127 B-90/50
`
`“Coline=ss ttts*=i«s=‘i BHAA|SBS AC0IKG | NBI155 A087
`
`
`
`
`Cortexolone B-21/48|SG-301 B-60/49|NG-301| B-90/50
`
`
`
`
`=CottexoloneAcetate B-21/48|SG-311 B-60/49|NG-311cea B-90/50_
`
` Corticosterone 21-Acetate A-21/45|SG-171 A-60/46|NG-171 A-90/47Uy
`
`
`
`
`
`
`Cortisone B-21/48|SG-121 B-60/49|NG-121 B-90/50
`
`
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`
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`Cortisone Acetate B-60/49|NG-181: B-21/48 | $G-181 B-90/50
`
`
`
`
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`
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`(-)Cotinine A-21/45|SK-124 A-60/46|NK-124 A-90/47
`
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`Corticosterone A-21/45|SG-111 A-60/46|NG-111 A-90/47
`
`
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`
`
`Coumarin (1, 2 Benzopyrone) ¢-60/52|NC-112c-21/51.| Sc-112 C-90/53
`
`H-90/62
`
`
`
`
`
`
`
`Cromolyn B-21/48|SC-195 B-60/49|NC-195 B-90/50
`
`
`
`
`
`
`
`
`
`
`
`~ Crotaline D-21/54|SK-125 D-60/55|NK-125 D-90/56
`
`
`
`Cyclizine A-21/45|SC-108 A-60/46|NC-108 A-90/47
`
`
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`
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`Cyclophosphamide (cytoxan) A-21/45|$Z-150 A-60/46|NZ-150 A-90/47
`
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`
`
`D-Cycloserine B-21/48|SB-128 B-60/49|NB-128 B-90/50
`
`Cymarin p-21/54|Sc-382 D-60/55|NC-382 D-90/56
`
`
`
`
`
`
`Cyproheptadine A-21/45|SC-481 A-60/46|NC-481 A-90/47
`
`
`
`
`
`
`
`-Cyproterone Acetate E.21/57.|SC-114 60/58|NC-114 E-90/59
`
`D-Cysteine C-21/51|SQ-201 C-60/52|NQ-201 C-90/53
`
`
`
`
`
`
`
`_‘LCysteine ¢-21/51|$@-211 C-60/52|N@-211| C-90/53
`
`
`
`
`
`
`
`D-Cystine p-21/54|$Q-221 D-60/55|NQ-221 D-90/56
`
`L-cystine 6-21/51|$@-231 €-60/52|NQ-231: C-90/53
`
`
`
`
`
`
`
`Cytarabine(Cytosine Arabinoside) D-21/54|SZ-160 D-60/55|NZ-160 D-90/56
`
`- Gytisine E-21/57|SK-126 E-60/58|NK-126| | £-90/59
`
`
`
`
`
`
`
`
`Cytosine c-21/51|SN-241 C-60/52|NN-241 C-90/53
`
`
`
`
`
`
`
`Danazol p-21/54|SP-251 D-60/55|NP-251 D-90/56
`
`
`
`
`
`Daunorubucine H-21/60|SZ-170 H-60/61|NZ-170
`
`26
`
`a
`
`AstraZeneca Exhibit 2044 p. 32
`
`

`

`C-60/52
`
`Dexamethasone
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`Dexamethasone 21-Phosphate
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`
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`
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`
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`
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`
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`
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`
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`
`B-156
`
`B-21/48
`
`SB-156
`
`B-60/49
`
`NB-156
`
`E-181
`
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`
`SE-184
`
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`
`NE-181
`
`B-90/50
`
`6.90/53
`
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`
`E-191
`
`C-21/51
`
`SE- 191
`
`NE-191
`
`C-90/53
`
`AstraZeneca Exhibit 2044 p. 33
`
`Desipramine
`
`- Desoximetasone
`
`C-491
`
`B-21/48
`
`SC-491
`
`B-60/49
`
`NC-491
`
`D-107
`
`D-21/54
`
`SD-107
`
`D-60/55.
`
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`
`NMA121
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`G-131
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`SG-131
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`D-108
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`SD-108
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`
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`
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`
`153
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`156
`
`62
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`ALPHABETICAL PRODUCT LISTING
`
`a D
`
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`
`Product
`
`3-Deazauracil
`
`\3-Deazauridine
`
`21-Day Release
`Catalog Price Schedule/
`Number Page Number
`
`60-Day Release
`Catalog Price Schedule/
`Nomber Page Number
`
`90-Day Release
`
`Catalog Price Schedule/
`Number Page Number
`
`N-251
`‘N-261°
`
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`
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`
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`
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`
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`
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`
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`
`V-281
`
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`
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`
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`
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`
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`
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`
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`
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`
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