`
`Vol 170, No 17 October 26, 2004
`
`Supplement tll Circulation
`
`Children with Normal Atrioventricular Conduction, 1846
`Impact of Conventional Versus Biventricular Pacing on Hemodynamics and
`Tissue Doppler Imaging Indices of Resynchronization in Postoperative
`Children with Right Ventricular Conduction Delay, 3517
`Impact of Genetic Syndromes on Surgical Correction of Tetralogy of Fallot,
`3412
`Impaired Cerebral Oxygenation is Commonin the Perioperative Norwood
`Period, 2887
`Impairment of Primary Hemostasis (Type Ila von Willebrand Syndrome) in
`Obstructive Cardiomyopathy: Close Correlation with the Severity of
`Obstruction, 3626
`;
`Incidence and Risk Distribution of Heart Failure in Grown ups with
`Congenital Heart Disease in the Long-Term Follow-up After Cardiac
`Surgery, 3633
`Interactive Real-Time Magnetic Resonance—Guided Atrial Septal Puncture
`and Atrial Balloon Septostomy are Feasible in Swine, 3199
`Intermediate Follow-Up of Native and Recurrent Coarctation Stent Repair:
`Is Integrated Imaging of the Aortic Arch Necessary? A Multi-Institutional
`Study, 2634
`Intracardiac Thrombus in Adults with Fontan Operation: Treatment and
`Clinical Outcome, 3630
`Intracoronary Ultrasound Assessment Late after the Arterial Switch
`Operation for Transposition of the Great Arteries, 3195
`Late Atrial Tachyarrhythmia and Survival in 740 Patients after Fontan
`Operation: A Japanese Multicenter Study, 3021
`Levosimendan Reduces Increased Pulmonary Vascular Resistancein
`Children after Cardiac Surgery, 2479
`Living Heart Valve Tissue Engineered from Human Umbilical Cord Blood
`Progenitor Cells, 2481
`Long-term Right Ventricular Apex Pacing in Patients with Congenital AV
`Block Does Not Have a Detrimental Effect on Ventricular Function, 1651
`Magnetic Resonance Myocardial Delayed Enhancementin Infants with
`Anomalous Origin of Left Main Coronary Artery from Pulmonary Artery,
`3488
`Mesenteric Blood Flow Velocities in the Newborn with Single Ventricle
`Physiology: Modified Blalock-Taussig Shunt vs. Right
`Ventricle-Pulmonary Artery Conduit, 2083
`Modification of Stage 1 Palliation Following Fetal Aortic Valvuloplasty,
`2888
`MR-Guided Cardiac Catheterization in Children and Adults, 2840
`Multidetector CT with Three-dimensional Reconstruction: Evaluation of
`Systemic and Pulmonary Vasculature and Tracheobronchial Tree in
`Newborns and Infants, 1845
`Multislice Computed Tomography Accurately Quantifies Right Ventricular
`Size and Function in Adults with Congenital Heart Disease, 3018
`Mutation in the KCNQ1 Gene Leading to the Short-OT-Interval Syndrome,
`1105
`Neointimal and Medial Thickening of Aortopulmonary Collateral Arteries in
`Organ Culture, 3406
`Neurohormone and Cytokine Activation Relate to Symptoms and Cardiac
`Function as Quantified by Cardiovascular Magnetic Resonance late
`After Repair of Tetralogy of Fallot, 3016
`Novel Downstream Targets of the Homeodomain Transcription Factor
`Nkx2.5 Identified Through Transcriptional Profiling, 1379
`Outcome Predictors in Pediatric Hypertrophic Cardiomyopathy, 2080
`Parental Factors Impacting the Enrollment of Children in Cardiac Critical
`Care Clinical Trials, 2079
`:
`Patent Foramen Ovale In Obstructive Sleep Apnoea, 2224
`Pediatric Heart Transplantation at Stanford: Analysis of Three Decades of
`Experience, 2715
`Percutaneous Pulmonary Valve Implantation Improves Haemodynamics
`And Early Exercise Capacity, 2066
`Postoperative Outcomes of Bidirectional Cavopulmonary Connection
`Performed After a Stage | Palliation with a Right Ventricular to
`Pulmonary Artery Conduit Versus a Modified Blalock-Taussig Shunt,
`2876
`Pulmonary Arterial Thrombosis in Eisenmenger Syndromeis Associated
`with Ventricular Dysfunction, Neurohormonal Activation, and Poorer
`Exercise Capacity, 3631
`Quality of Life and Family Impact in Survivors of Single Ventricle
`Congenital Heart Disease, 2881
`Quality of Life in Children with Heart Disease: The Parents’ Perspective,
`3035
`Remote Ischemic Preconditioning Reduces MyocardialInjury in Children
`Undergoing Open Heart Surgery, 2644
`Right Atrial and Ventricular Adaptation to Chronic Right Ventricular
`Pressure Overload, 1887
`Right Ventricular Myocardial Fibrosis Late after Repair of Tetralogy of
`Fallot Demonstrated by Late Gadolinium Cardiovascular Magnetic
`Resonance: Correlation with Right Ventricular Dysfunction,
`Neurohormonal Activation, and Exercise Intolerance, 3017
`Roles of CHF1/Hey2 in Endocardial Cushion Remodeling, Myocardial
`Maturation and Vascular Development, 277
`Salvage Cardiac ECMO: We Can Do It, But Should We?, 2889
`
`Serum Angiogenic Activity |s Increased In Patients with Cyanotic
`Congenital Heart Disease, 1836
`Significance of Enhanced P-Selectin Expression on Platelets and
`Decreased Thrombomodulin in Patients with Cyanotic Congenital Heart
`Disease, 2882
`Single-Ventricle Palliation with Right Ventricle to Pulmonary Artery Condult:
`Early Outcomes and ICU Course Compared with the Traditional
`Norwood Operation, 2890
`Spiral Computed Tomography with Three-Dimensional Reconstruction for
`Evaluating Tracheal Compression in Children with Vascular Ring and
`Pulmonary Artery Sling, 1849
`Tetralogy of Fallot for Morphologically Equivalent Infants: Repair with
`Annulus Preservation Compared to a Transannular Patch Yields
`Improved Mid-Term Right Ventricular Dimensions, 3411
`The Efficacy of a Novel Biodegradable Material with in Situ
`Recellularization for Reconstruction of the Arterial Wall in Cardiovascular
`Surgery, 2645
`The Influence of Transplant versus Reconstructive Approach on
`Neurodevelopmental Outcome in Hypoplastic Left Heart Syndrome,
`2475
`The Relationship of Medical and Patient Characteristics to Health-Related
`Quality of Life in Adolescents after the Fontan Procedure, 2077
`The Role of Neonatal Electrocardiographyin the Early Identification of
`Genetic Arrhythmogenic Disorders and Congenital Cardiovascular
`Diseases: Prospective Data from 21,000 Infants, 1930
`The Ross Procedure in Infancy Followed into Late Childhood, 2483
`Transcatheter Closure of Interatrial Defects in Patients With Pulmonary
`Hypertension, 3024
`Transcatheter Closure of Perimembranous Ventricular Septal Defects using
`the Amplatzer Membranous VSD Occluder: Immediate and mid-term
`results, 2631
`Transcatheter Closure of Perimembranous Ventricular Septal Defects using
`the New Amplatzer Membranous VSD Occluder: Result of the U.S.
`Phase | Trial, 2632
`Truncus Arteriosus Associated with Interrupted Aortic Arch in 50
`Neonates: A Congenital Heart Surgeon Society Study, 2482
`Upregulation of Hypoxia Inducible Factor Reduces Neuronal Loss in
`Neonatal Piglets Undergoing Deep Hypothermic Circulatory Arrest, 1885
`Use of an Allograft Patch in Repair of Hypoplastic Left Heart Syndrome
`May Complicate Future Transplantation, 3413
`Use of Mathematical Modelling to Compare and Predict Hemodynamics of
`the Norwood and the Sano operations for hypoplastic left heart
`syndrome, 2476
`Zebrafish (Danio rerio) model of Barth Syndrome, 215
`
`Contractile proteins
`Alphas Integrin Downregulation by siRNA Increases Vascular Smooth
`Muscle Cell Migration: Implication in Restenosis After Angioplasty, 1482
`Ca**-Sensitizing Effect of Familial Hypertrophic Cardiomyopathy-Linked
`Troponin T Mutation Reduces Contractile Reserve of Mouse Heart, 509
`Carboxyl-terminal Fragment of Myosin Light Chain Kinase Increases Actin
`Translocation Velocity of Cardiac Muscles, 968
`Cardiomyocyte Stiffening in Diastolic Heart Failure, 2956
`Contractile Dysfunction in Human Chronic Atrial Fibrillation Is Associated
`with Hyperphosphorylation of Phospholamban and Phosphatase
`Inhibitor-1, 64
`Directed Differentiation of Adult Human Bone Marrow Stem Cells into
`Lineage-Defined Cardiac Muscle-Like Cells , 445
`Faster Decay of Crossbridge Dynamics during Diastole in Endomyocardial
`Region Compared with Epimyocardial Region, 521
`Functional Comparison of Two Missense Mutations in Troponin C
`Identified in a Patient with Idiopathic Dilated Cardiomyopathy, 2954
`Hyperinsulinemia Activates Vascular AngiotensinIl in Humans, 2043
`Increasing Myofilament Ga** Sensitivity Causes Action Potential
`Remodeling, Afterdepolarizations, and Ventricular Arrhythmias, 781
`Mechanical Strain Affects Vascular Smooth Muscle Phenotype on
`Micropatterned Surfaces, 1513
`Modifications to Troponin C with Brief Ischemia/ReperfusionInjury, 1540
`Muscle-specific Ring Finger 1 is a Bona Fide Ubiquitin Ligase that
`Degrades Cardiac Troponin |, 762
`Protein Kinase A Corrects High Resting Tension Of Cardiomyocytes From
`Patients With Diastolic Heart Failure, 2094
`Short Interfering RNA-mediated Silencing of Cardiac Obscurin Gene: Block
`of Hypertrophic Response and Effect on Myofibrillogenesis, 1537
`Structure-Function Relationships of Eight Mutations in Troponin and
`Tropomyosin that Cause Dilated Cardiomyopathy, 57
`The Cardiac Myosin Activator, CK1122534, Increases Contractility in Adult
`Cardiac Myocytes but Does Not Affect the Calcium Transient or Depend
`on Second MessengerSignaling, 2256
`The Functional and Opposing Effects of PKA and PKC Phosphorylation on
`Cardiac Troponin |, 1282
`The Internal Troponin-T Binding Domain of Striated 8-Tropomyosin Alters
`Heart Physiology and Blunts Adrenergic Response without Altering
`Myofilament Calcium Sensitivity, 455
`
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`Supplied by the British Library 24 Apr 2018, 20:23 (BST)
`UNITED THERAPEUTICS, EX. 2096
`WATSON LABORATORIES v. UNITED THERAPEUTICS, IPR2017-01621
`Page 108 of 262
`
`
`
`Subject Index
`
`W943
`
`Pantoprazole Induces A Dose-Dependent And Reversible Depression Of
`The Prominent a-Adrenergic Inotropic Effect in Human. Atria Depends on
`Contractile Function In Human Myocardium, 141
`Myosin Light Chain Phosphorylation, 1286
`and Depolymerization of the Intermediate Filament Protein
`Vimentin is Regulated by p21-protein Kinase During Stimulation of
`Contractility
`Smooth Muscle, 1026
`&-Opioid Receptor Agonist Reduces the Severity of Postresuscitation
`2493
`Protein Kinase A Corrects High Resting Tension Of Cardiomyocytes From
`Myocardial
`1"
`Patients With Diastolic Heart Failure, 2094
`3-lodothyronamine is a Novel Endogenous Modulator of Cardiac Inotropic
`State, 1234
`Quantitative Assessment of Regional Myocardial Function in Mice by
`Teed Doppler Wane: COM ennneete eee
`A Novel Chimeric Molecule that Exhibits Simultaneous §-Adrenoreceptor
`Blockade and Cardiac Inotropy in the Heart, 965
`Reversal of Cardiac
`by the Conditional Expression of
`A Tissue Engineered Myocardial Patch Derived from Extracellular Matrix
`Glycogen Synthase Kinase (GSK) 3-8in the Pressure-Overloaded Heart,
`Performs Regional Mechanical Work, 1884
`5I
`Ablation of Junctin by Gene Targeting Results in Enhanced Cardiac
`Short Interfering RNA-mediated Silencing of Cardiac Obscurin Gene: Block
`Contractility and Ca®* Kinetics, 622
`of Hypertrophic Response and Effect on Myofibrillogenesis, 1537
`Adenyly! Cyclase Type V Deletion is Associated with Increased Basal Left
`Signs Of Systolic And Diastolic Heart Failure In Caveolin-1 Knockout Mice
`Ventricular Function, but Decreased Response to B-Adrenergic
`Establish A Crucial Role Of Caveolin-1 In Cardiac Perfomance, 23
`Receptor Stimulation, 1220
`Sildenafil Attenuates the Inotropic Response to 6-1 Stimulation in Humans,
`Angiogenesis but not Arteriogenesis Supports Regional Contractility in
`2806
`Chronic Myocardial Ischemia, 1292
`Structure-Function Relationships of Eight Mutations in Troponin and
`Arterial Input Impedance,Arterial Function, and Ventricular-Vascular
`Tropomyosin that Cause Dilated Cardiomyopathy, 57
`Interaction in the Mouse Assessed with the Conductance Catheter, 522
`Survival after Levosimendan Compared to Dobutamine, 2486
`Ca?*-Sensitizing Effect of Familial Hypertrophic Cardiomyopathy-Linked
`The Cardiac Myosin Activator, CK1122534, Increases Contractility in Adult
`Troponin T Mutation Reduces Contractile Reserve of Mouse Heart, 509
`Cardiac Myocytes but Does Not Affect the Calcium Transient or Depend
`Carboxyl-terminal Fragment of Myosin Light Chain Kinase Increases Actin
`on Second Messenger Signaling, 2256
`Translocation Velocity of Cardiac Muscles, 968
`The Internal Troponin-T Binding Domain of Striated B-Tropomyosin Alters
`Cardiac Adenoviral S100A1 Gene Delivery Rescues Contractile Function of
`Heart Physiology and Blunts Adrenergic Response without Altering
`Failing Myocardium, 4
`Myofilament Calcium Sensitivity, 455
`Cardiac Repair with Mesenchymal Stem Cells following Myocardial
`The Optima! Adrenergic Agent for Cardiopulmonary Resuscitation, 2492
`Infarction in Pigs, 815
`The Volume-Sensitive Chloride Channel Antagonist |AA-94 Prevents both
`Cardiomyocyte Stiffening in Diastolic Heart Failure, 2956
`Contractile Dysfunction and Apoptosis Induced By Doxorubicin in Adult
`Overexpression of Endothelial Nitric Oxide
`Isolated Cardiomyocytes, 136
`Synthase (NOS3) Potentiates Postsynaptic Vagal Inhibition of Cardiac
`Ultrasound Tissue Characterization may be used to Detect Subclinical Left
`Contraction In Vivo and In Vitro, 523
`Ventricular Dysfunction and Fibrosis in Asymptomatic Severe Mitral
`Chronic Xanthine Oxidase Inhibition Attenuates the Development of
`Regurgitation, 2736
`B-adrenergic Hyporesponsiveness and Altered Calcium Cycling Proteins
`Use-Dependent f2-Adrenergic Receptor-Gi Coupling Requires RGS and
`in Chronic Pacing-induced Heart Failure, 2952
`B-ARK/PKA-Mediated Receptor Phosphorylation, 433
`Complete Restoration of Atrial Contractility by the Atrial K*-channel
`Blocker AVE0118 after Cardioversion of Atrial Fibrillation in the Goat,
`Contrast echo
`459
`Can Myocardial Contrast Echocardiography Replace Radionuclide
`Differences in Development of Cardiac Contractile Dysfunction in Mice
`Perfusion Imaging for the Detection of Residual Infarct-Related Artery
`Models of Type Il Diabetes and the Metabolic Syndrome, 493
`Stenosis and Multivesse! Disease Following Acute Myocardial
`Direct Regulation of SERCA Activity by S-Glutathiolation at Cys674 by
`Infarction?, 3457
`Peroxynitrite, 427
`Coronary Flow Reserve by Contrast-Enhanced Transthoracic
`Doppler-derived Ejection Intraventricular Pressure Gradients Provide a
`Echocardiography: a New Noninvasive Predictor of Cardiac Allograft
`Reliable Assessment of Left Ventricular Contracility, 1997
`Vasculopathy, 2720
`Effects of Urocortin II in Isolated Cardiac Myocytes from the Muscle LIM
`Development of a Novel Microbubble Agent for Ultrasound-Mediated
`Protein Knockout Mouse, a Model for Dilated Cardiomyopathy: Bypass
`Targeted Drug Delivery, 2395
`of Blunted B-Adrenergic Response in Heart Failure, 2810
`Differentiation of Arteriogenesis from Capillary Perfusion with Contrast
`Esmolol Administered During CPR Improves Resuscitation, 1858
`Ultrasound During Therapeutic Angiogenesis, 2388
`Functionally Opposing Roles of Extracellular Signal-Regulated Kinase and
`Drag-Reducing Polymers Increase Capillary Volume and Improve Coronary
`p38 Mitogen-Activated Protein Kinase in the Regulation of Cardiac
`Flow Reserve During Coronary Stenosis, 3462
`Contractility, 508
`Effect of Transthoracic Ultrasound and Intravenous Microbubbles on
`Heme oxygenase-1 Induction Improves the Viability of Adult
`Sympathetic Nerve Activity in Rabbits, 2393
`Cardiomyocyte Cellular Grafts in Vivo, 1446
`Enhancement ofin vivo Clot Visualization and Ultrasound Thrombolysis
`Human (N27K) Phospholamban Exacerbates Stress-induced Cardiac
`Using Microbubbles Targeted to Activated Platelets, 3460
`Hypertrophy and Ischemic Injury, 56
`Functional Border Zone in Acute Myocardial Ischemia: Assessment by
`Human Atrial Fibrillation is Associated with an Alteration in Calcium
`Tissue Strain and Myocardial Contrast Echocardiography, 3321
`Cycling Protein Expression without Change in Contractile Protein
`Identification of Risk Area and Infarct Zone Myocardium from the Contrast
`Hyperenhancement Visualized After Occlusion/Reperfusion using
`Delayed Imaging and Exposure to High-Energy Ultrasound, 3317
`impact of Infarct Transmurality on Transmural Blood Flow in Patients with
`Chronic Left Ventricular Ischemic Dysfunction, 3319
`Impact of Microbbuble Shell and Mode of Contrast Administration on
`Microvascular Integrity and Myocardial Function During Contrast
`Echocardiography, 3463
`In Vivo Validation of Quantitative Evaluation of Myocardial Perfusion from
`Image Sequences of Transient Contrast Inflow , 3322
`Incremental Prognostic Value of Contrast-Enhanced Dobutamine Stress
`Echocardiography in the Prediction of Cardiovascular Outcome in Heart
`Transplant Recipients, 2400
`Incremental Value of Myocardial Microvascular Abnormalities and Left
`Ventricular Systolic Strain Rate in Predicting Cardiac Events in Patients
`With Dilated Cardiomyopathy , 2565
`Influence of Collateral Flow on Phasic Changes in Myocardial Acoustic
`Intensity Leads to Underestimation of Stenasis Severity on Myocardial
`Contrast Echocardiography, 3459
`Intracoronary Hyperbaric Oxygen Administered During Primary
`Percutaneous Coronary Intervention Prevents One Month Left
`Ventricular Remodeling , 3229
`Intravenous Adenosine Improves Microvascular Reflow Assessed by
`Contrast Echocardiography in Patients with Acute Myocardial Infarction,
`3323
`Intravenous Delivery of Autologous and Allogenic Mesenchymal Stromal
`Cells Limits infarcts Size and Improves Left Ventricular Function in the
`
`Isovolumic Contraction Velocity is a Potential Measurement of Left
`Ventricular State of Contractility: A Simultaneous Pulsed Doppler Tissue
`Imaging and Cardiac Catheterization Study, 1732
`Left Ventricular
`y is Associated with Normal Segmental Wall
`Motion at the Site of Myocardial Infarction, 1995
`Left Ventricular Pressure-Volume Relationship in Conscious Mice, 3373
`Levosimendan for Management of CPR, 2484
`Levosimendan Improves Postresuscitation Myocardial Function in a
`Porcine Model of Cardiac Arrest and Resuscitation, 1856
`Long-term Inhibition of RhoA Enhances Endothelial NO Production and
`Reduces Vascular Tone in an Intact Artery, 731
`Mechanism of RhoA/Rho Kinase in Stretch-induced Myogenic tone, 1175
`Mitochondrial K-ATP Channel Activation by Levosimendan Protects
`Cardiac
`from Oxidant Stress-induced Apoptosis and
`Contractile Dysfunction, 2255
`Modulation of the 6-adrenergic receptor kinase improves cardiac function
`in a neonatal model ofright ventricular hypertrophy, 1281
`Myocardial Dysfunction by MRI Tagging !s Directly Related To Reduced
`Coronary Flow Reserve by MRI Perfusion in Asymptomatic Participants
`of the Multi-Ethnic Study of Atherosclerosis, 3491
`p38 MAP Kinase Mediates Progressive Right Ventricular Force Decline
`after Acute Stretch, 1285
`
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`UNITED THERAPEUTICS, EX. 2096
`WATSON LABORATORIESv. UNITED THERAPEUTICS, IPR2017-01621
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`Supplement Ill Circulation Vol.110, No 17 October 26, 2004
`I-944
`Infarcted Porcine Heart, 1199
`'s Myocardial Contrast Echo Accurate for the Diagnosis of Coronary Artery
`Disease in Diabetic Patients?, 3320
`Mast Cells as a Backstay for ReducingPostinfarction Ventricular
`Remodeling through Promotion of Angiogenesis in Peri-Infarct Zones,
`121
`Myocardial Contrast Echocardiography is a Powerful Long-term (up to 6
`Years) Predictor for Cardiac Events in Patients With Known or
`
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`
`;
`
`c
`
`Myocardial Contrast Echocardiography Provides Superior Information
`Compared With the TIMI Score in Patients Presenting to the Emergency
`Department with Suspected Cardiac Chest Pain and a Nondiagnostic
`Electrocardiogram, 1606
`Myocardial Delivery of Nanoparticles by Ultrasound-Targeted Microbubble
`Destruction, Is Transient Dysfunction the Price to Pay 7, 2387
`Myocardial Perfusion as Measured with Real-Time Myocardial Contrast
`Echocardiography in Healthy Volunteers Correlates with Positron
`Emission Tomography, 3324
`Myocardial Perfusion Imaging and Quantification Using Interrupted
`Contrast Infusion, 3318
`Novel Echogenic Tissue Plasminogen Activator-Loaded Liposomes for
`Site-Specific Thrombolysis, 2390
`Quantitative Myocardial Contrast Echocardiography Can Illustrate
`tsiasibadgs orpiebal pelagecireyh colton ALESrsgag
`Infarction: Validation Using Tissue Doppler Imaging, 2392
`Real-Time Myocardial Contrast Echocardiography, Perfusion Quantitative
`Analysis, and Heterogeneity in Hypertrophic Obstructive
`Cardiomyopathy, 3139
`Reduced Coronary and Myocardial Flow In Severe Aortic Stenosis Is
`Associated With Increased Myocardial Apoptosis, 3445
`Regional Heterogeneity of Myocardial Blood Flow Velocity Reserve in
`Non-ischemic Cardiomyopathy is Associated with Increased OT
`Dispersion, 3315
`Role of Coronary Flow Reserve with Contrast-Enhanced Dobutamine
`Stress Echocardiography in Predicting Outcome in Patients with Known
`or Suspected Coronary Artery Disease, 2728
`Targeted Ultrasound Imaging of Apoptosis in Acute Myocardial Injury with
`Annexin-A5 Microspheres, 2386
`The Role of Complement in Microbubble Adherence to Dysfunctional
`Arterial Endothelium, 3461
`Tissue-Level Perfusion Predicts Remote Clinical Outcomes More
`Accurately than Relaxation Abnormality in Patients with Myocardial
`Infarction, 3316
`What Is the Relationship between Flow and Function in Diabetic
`Cardiomyopathy? A Quantitative Study Using Contrast Echo and Strain
`Rate Imaging, 2394
`Contrast media
`N-Acetyicysteine Prophylaxis Significantly Reduces the Risk of
`Radiocontrast-Induced Nephropathy: Comprehensive Meta-Analysis,
`1797
`A Prospective, Randomised Trial to Determine Early and Late Reactions
`After the Use of lopamidol 340 and lobitridol 350 in Cardiac
`Catheterisation, 1798
`
`Undergoing Coronary Angiography
`But Not In Patients Submitted To Iso-Osmolar Contrast Media - A
`Meta-Analysis, 1794
`Atherosclerotic Plaque Detection by Contrast-Enhanced MRI: Gadofluorine
`vs Gd-DTPA, 3175
`Contrast Nephropathy and Visipaque Use in Routine Clinical Practice of
`Percutaneous Coronary Intervention: Insights from Toronto General
`Hospital PC! Registry, 2319
`Detection of VCAM-1 Expression on Activated Endothelial Cells by
`Magnetic Resonance immunohistochemistry (MRlhc) Using Targeted
`Iron Oxide Nanoparticles, 3174
`Differences of Gd-DTPA Kinetic in Normal, Stunned and Necrotic
`Myocardium in Patients with Acute Myocardial Infarction, 2838
`Early versus Advanced Atherosclerotic Plaque in vivo Detection by
`Gadofluorine-Enhanced Magnetic Resonance Imaging, 177
`Fibrin-Targeted Contrast Enhancing Agent for Acute and Chronic
`Thrombus Detection with Magnetic Resonance Imaging in vivo, 1189
`Imaging Atherosclerotic Plaques with an Endogenous Contrast Agent:
`HDL, 3435
`Lower Hematocrit Predicts Contrast Induced Nephropathy after
`Percutaneous Coronary Interventions , 2865
`MR Perfusion Imaging for Detection of Coronary Artery Disease: A
`Multicenter Dose Finding Study in Comparison with X-Ray Coronary
`Angiography and Single Photon Emission Computed Tomography, 2987
`N-Acetyicysteine in the Prevention of Radiocontrast-induced Nephropathy
`
`No Reflow Detected by Delayed Contrast Enhancement Predicts
`Ventricular Remodeling Following an ST-Segment Elevation Myocardial
`Infarction, 2091
`
`Paramagnetic a,b,-Integrin-Targeted Fumagillin Nanoparticles for
`Combined Molecular Imaging and Antiangiogenic Therapy in
`Atherosclerosis, 1463
`Quantification of Myocardial Perfusion Using Real-Time Three-Dimensional
`Echocardiographic Imaging . 2391
`Selection of Contrast Media in Patients with Chronic Renal Insufficiency:
`Pooled Analysis of Recent Randomized Trials, 2318
`The Effect of Contrast-induced Nephropathy on Long-Term Mortality After
`Percutaneous Coronary Interventions: A Prospective Epidemiological
`Study, 2316
`The Prevention of Radiocontrast-Induced Nephropathy Trial (PRINT): A
`Prospective, Double-Blind, Randomized, Controlled Trial of Iso-Osmolar
`Versus Low-Osmolar Radiocontrast in Combination with
`N-Acatylcysteine Versus Placebo, 1795
`
`Coronary artery disease
`Effects of Antibiotic Treatment on Outcomes of Patients with Coronary
`Artery Disease: A Meta-Analysis, 2118
`Preoperative Prediction of Long-Term Survival Following Coronary Artery
`Bypass Grafting in Patients with Low Left Ventricular Ejection Fraction:
`The HAVOC Score, 1986
`150-Microgram Intracoronary Adenosine Bolus Is Mandatory For Accurate
`Fractional Flow Reserve Measurement In Intermediate Lesions: A
`Dose-Ranging Study, 1919
`16-row CT Coronary Angiography in Heart Transplant Patients, 2102
`3-Year Follow-Up of TAXUS |: A Randomized, Controlled Study with
`Polymer-Based Paclitaxel-Eluting Stents for Coronary Artery Lesions,
`2464
`A Common Polymorphism in the ABCA1 Gene (G1051A) is Associated
`with a Lower Prevalence of Coronary Calcification in the Multiethnic
`Study of Atherosclerosis (MESA), 3801
`A Randomized Comparison of Off-Pump and On-Pump Multiple Arterial
`Coronary Revascularization, 2922
`A Randomized Double Blind Comparison Of Two Strategies For Managing
`Patients On Aspirin And Clopidogrel Therapy Requiring Urgent Coronary
`Revascularization, 1699
`Abnormal Glucose Regulation in Patients with Coronary Artery Disease:
`Experience from the Euro Heart Survey, 3677
`Aborted Off-Pump Coronary Artery Bypass Patients Have Worse
`Outcomes Compared With On-Pump and Successful Off-Pump Bypass
`Patients, 2549
`Accuracy of Noninvasive Monitoring of Coronary Flow Velocity Reserve
`with Transthoracic Echo-Doppler in Detecting Coronary Restenosis After
`Successful Coronary Angioplasty: a Multicenter Study, 2404
`Adaptive Arterial Remodeling In Patients Treated With A Stent-Based
`Ventricle-To-Coronary Artery Bypass (VSTENTTM): 1-Year Follow-Up
`Data Of The Munich Subset Of The ADVANTAGE Trial, 3271
`Addition of Nanomolar Concentrations of D-4F to Human Plasma In Vitro
`Causes the Movement of ApoA-l to Smaller Particles, Reduces Lipid
`Hydroperoxides, Increases Paraoxonase Activity, and Converts
`Proinflammatory HDL to Anti-inflammatory, 1165
`Adverse Impact Of Multivessel Disease On ST-segment Recovery And
`Clinical Outcome In Patients Undergoing Primary Percutaneous
`Coronary intervention For Acute Myocardial Infarction, 3075
`Adverse Psychological and Coronary Risk Profiles in Young Patients and
`Benefits of Formal Cardiac Rehabilitation, 3664
`Anaerobic Periodontal Infection, Coronary Heart Disease, and the Acute
`Coronary Syndrome, 1686
`Angiographic Evaluation of the Quality of Anastomosis in Exclusive Internal
`Thoracic Artery Myocardial Revascularization for Patients with Triple
`Vessel Disease, 2209
`Are Patients with Human Immunodeficiency Virus at Higher Risk for
`Complications Following Cardiac Surgery?, 1688
`Aspirin Resistance Is Associated With Markers of Platelet Activation and Is
`Not Accounted For By Noncompliance Or Aspirin Underdosing, 1032
`Assessment of Compensatory Remodeling and Plaque Distribution of
`
`-
`
`the Latest Multislice Detector Computed Tomography with 370 msec
`Gantry Rotation Time, 2105
`Association Between Enhanced Soluble CD40L And Prothrombotic State
`In Major Depression, 1479
`Association Between Lipoprotein-Associated Phospholipase A2 and
`Coronary Artery Disease: Focus on its Relationship With Lipoproteins
`and Markers of Inflammation and Hemostasis, 3577
`Association of Metabolic Risk Factor Burden with Coronary, Aortic, and
`Aortic Valve Calcium, 3683
`Bare Metal Stent Restenosis is Not a Benign Clinical Entity , 1815
`Beneficial Effect of Pre-Operative Aspirin Therapy on Post-Operative
`Outcomes in Patients Undergoing Coronary Artery Bypass Grafting,
`2210
`Both Albuminuria and Framingham Risk Score Predict Cardiovascular
`Events in Albuminuric Subjects with Intermediate Cardiovascular Risk,
`3650
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`UNITED THERAPEUTICS, EX. 2096
`WATSON LABORATORIES v. UNITED THERAPEUTICS, IPR2017-01621
`Page 110 of 262
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`Both World Health Organization and National Cholesterol Education
`Program Definitions of the Metabolic Syndrome Independently Predict
`Subclinical Atherosclerosis, 3841
`Carvedilol Restores Attenuation of Cardioprotection by Ischemic
`Preconditioning in the Chronic Ischemic Heart, 505
`Cerebral Injury Following On-Pump and Of-Pump Cardiac Surgery Defined
`by Functional Magnetic Resonance Imaging, 2550in British Columbia,
`
`Changing Trends in CABG surgery: Comparison of Three Time Intervals
`over a 9-year Period, 2548
`Chlamydia pneumoniae in Peripheral Blood Cells is Associated With
`
`The Impact of Physical Exercise, 3574
`Cilostazol Reduces Restenosis in Diabetic Patients after Coronary Stent
`implantation, 2306
`Circulating B-type Natriuretic Peptide and N-Terminal pro-B-type
`Natriuretic Peptide as Markers of Long-term Survival in Patients with
`Stable Coronary Artery Disease , 3263
`Circulating OxLDL-E06 Levels Reflect the Presence and Extent of
`Angiographic Coronary Artery Disease: Strong Association Between
`Circulating Oxidized Phospholipids and Lp{a) May Potentially Mediate
`Atherogenicity, 870
`Clinical and Angiographic Outcomes following Crush Bifurcation Stenting
`with Drug-Eluting Stents: Low Target Lesion Revascularization Rates but
`High Rate of Side-Branch Restenosis in the Absence of Kissing Balloon
`after Dilatation, 3498
`Clopidogre! Administration Prior To CABG:The Cardiologist's Panacea Or
`The Surgeon's Headache 7, 2930
`Combination Therapy With Gemfibrozil, Niacin, and Cholestyramine
`Reduces the Prevalence of Metabolic Syndrome Above and Beyond
`Aggressive Lifestyle Modification and Dietary Restriction, 3785
`Combined Use of 16-Slice Computed Tomography and Adenosine Stress
`MRI for Detecting Hemodynamically Significant Coronary Artery
`Disease, 2099
`between Optical Coherent Tomography (OCT) and Integrated
`Backscatter Intravascular Ultrasound (IB-IVUS) Images for Tissue
`Characterization of Human Coronary
`2463
`
`Tachycardia in Postinfarction Patients, 2711
`Comparison of Retrospectively ECG-Gated, Multislice Spiral Computed
`Tomography and Coronary Angiography in the Detectability of In-Stent
`Restenosis after Left Main or Ostial Coronary Stenting, 2615
`Complete Revascularization Significantly Improves Survival Following
`Percutaneous Coronary Intervention in Patients with Multivessel
`Disease, 2857
`Constant Fractional Flow Reserve Despite Changes in Coronary Stenosis
`and Microvascular Resistance After Hemodynamic Provocation, 1921
`Contrast Nephropathy and Visipaque Use in Routine Clinical Practice of
`Percutaneous Coronary Intervention:Insights from Toronto General
`Hospital PC! Registry, 2319
`Convergence of Genome-Wide Expression Analysis and Genome-Wide
`Linkage Analysis Identifies Candidate Genes for Atherosclerosis, 3799
`Coronary Artery Bypass Grafting in patients with Low Ejection Fraction ,
`2926
`Coronary Artery Calcification and Myocardial Perfusion in Asymptomatic
`Adults: the Multi-Ethnic Study of Atherosclerosis (MESA), 3687
`Coronary Artery Vasodilation by Magnetic Resonance Angiography !s
`Impaired in Asymptomatic Older Subjects with High Coronary Artery
`Calcium, 2836
`Coronary Calcifications in Patients with Elevated Levels of Lipoprotein (a),
`2285
`Coronary Calcium in Pima Indians with Childhood- and Young Adult-Onset
`Type 2 Diabetes, 3845
`Coronary Collateral Support Remains Recruitable Following Percutaneous
`Coronary Intervention, 1918
`Coronary Endothelial Dysfunction Provides Multiple Adverse Prognostic
`Impacts on Patients With Coronary Artery Disease During Long-Term
`Follow-up Over 100 Months, 2189
`Correlates of Progression of Coronary Artery Disease in Postmenopausal
`Women, 3658
`Declining Long-Term Efficacy of Vascular Brachytherapy for In-Stent
`Riestenosis: 5-Year Follow-Up from the Gamma 1 Randomized Trial,
`1923
`Depressionis a Predictor of Cardiovascular Events after Coronary Artery
`Bypass Graft, 2202
`Detection of Angiographically Silent Stenoses by Multislice Computed
`Tomography, 2104
`Detection of Coronary Artery Stenoses using Multidetector CT with
`370-ms Rotation and Submillimeter Collimation: a Segment-based
`Analysis, 2452
`Detection of Coronary Artery Stenoses with Whole Heart Coronary
`Magnetic Resonance Angiography, 2989
`
`Wl-945
`Subject Index
`Detection of Transplant Coronary Disease by Computed Tomography,
`2108
`Determinants of 1-Year Mortality in Patients with Stable Angina and First
`‘Angiographic
`of CAD: Results of the STAR Registry, 2916
`Dietary Calcium in Young Adulthood and Subclinical Coronary
`Atherosclerosis in Middle Age: The CARDIA Study, 3685
`Differential Effects of Serine Protease Inhibitors on MMP Release in
`Patients Following Cardiopulmonary Bypass, 1712
`Discovery and Replication of a Novel Polymorphism Associated with
`Coronary Disease Independent of Conventional Risk Factors in Two
`
`Revascularization? Results from PROVE-IT TIMI 22, 3220
`Does Right-Shifting Hemoglobin-Oxygen Dissociation Attenuate
`Exercise-induced Ischemia in Patients with Coronary Artery Disease?,
`2835
`Does the American Heart Association's Get with the Guidelines Program
`Improve the Quality of Cardiovascular Care in Hospitalized Patients with
`Diabetes?, 3699
`Drag-Reducing Polymers Increase Capillary Volume and Improve Coronary
`Flow Reserve During Coronary Stenosis, 3