I.
`
`Personal
`
`Name:
`
`Home Phone:
`
`Office Phone:
`
`Home Address:
`
`Krishna V. Komanduri, M.D.
`Curriculum Vitae
`
`Krishna V. Komanduri
`
`305-255-4780
`
`305-243-6355
`
`7600 SW 160th Terrace, Palmetto Bay, FL 33157
`
`Current Academic Rank:
`
`Professor of Medicine
`
`
`
`Current Track of Appointment: Tenure
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`Primary Department:
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`Medicine
`
`
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`Secondary or Joint Departmental Appointments: Microbiology and Immunology
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`Citizenship:
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`Visa Type (if non-citizen):
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`II. Higher Education
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`Institutional
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`USA
`
`N/A
`
`Degree-Granting Education
`Massachusetts Institute of Technology, Cambridge, Massachusetts, SB, 1987, Biology
`with humanities concentration in English Literature
`
`University of Minnesota Medical School, Minneapolis, Minnesota, MD, 1991, Medicine
`
`Postgraduate Training
`Internship and Residency in Internal Medicine, University of California, Los Angeles,
`California, 6/1991−6/1994
`
`Clinical Fellowship, University of California, San Francisco, California, 7/1994−6/1997
`
`Postdoctoral Fellowship, Gladstone Institute of Virology & Immunology, UCSF, San
`Francisco, California, Joseph (Mike) McCune, M.D., Ph.D., 6/1996−8/1999
`
`Board Certification
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`American Board of Internal Medicine, 8/1994
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`ABIM Certification in Medical Oncology, 11/1997
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`ABIM Certification in Hematology, 11/1998
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`ABIM Hematology Recertification, 2009 (exp. 12/31/2019)
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`Licensures
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`Active:
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`Florida Medical License, ME103316, 01/20/2017−1/31/2019
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`Inactive:
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`Texas Medical License, L7780, 12/2010−11/2012
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`California, G77378, 1/1993−1/2000
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`III.
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`Experience
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`Academic
`
`Laboratory Teaching Assistant, Introduction to Experimental Biology, Massachusetts
`Institute of Technology, Cambridge, Massachusetts, 9/1985−5/1987
`
`Course Faculty, Hematology Section, Introduction to Clinical Medicine, University of
`California-San Francisco School of Medicine, San Francisco, California, 1/1996−1/1999
`
`Assistant Professor, UCSF School of Medicine, San Francisco, California,
`1/1997−8/1999
`
`Assistant Professor, Department of Stem Cell Transplantation, Division of Cancer
`Medicine, UT M.D. Anderson Cancer Center, Houston, Texas, 7/1999−9/2006
`
`Associate Director of Cell Processing Laboratory, Department of Stem Cell
`Transplantation - Research, Division of Cancer Medicine, UT M.D. Anderson Cancer
`Center, Houston, Texas, 9/1999−8/2000
`
`Director of Clinical Fellowship Program, Department of Stem Cell Transplantation,
`Division of Cancer Medicine, UT M.D. Anderson Cancer Center, Houston, Texas,
`1/2000−2008
`
`Associate Director of Hematology/Oncology Fellowship Program, Department of Stem
`Cell Transplantation, Division of Cancer Medicine, UT M.D. Anderson Cancer Center,
`Houston, Texas, 1/2005−2008
`
`Associate Professor, Department of Stem Cell Transplantation, Division of Cancer
`Medicine, University of Texas, Houston, Texas, 9/2006−2008
`
`Director, Adult Stem Cell Transplant Program – Department of Medicine,
`Hematology/Oncology, University of Miami Sylvester Cancer Center Miami, FL 7/2008–
`Present
`
`Co-leader, Sylvester Cancer Center Tumor Immunology Program, 2010–2012
`
`Sylvester Cancer Center Administrative Committees: Past Member, Sylvester Executive
`Committee, Scientific Steering Committee and Recruitment Oversight Committee.
`
`Medical Director, Experimental and Clinical Therapies Lab (cGMP and cGTP
`laboratories supporting research and clinical cell therapies), University of Miami
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`Interdisciplinary Stem Cell Institute and Sylvester Cancer Center, Miami, FL, 2/2010–
`Present
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`Hospital Appointments:
`
`Associate Director for Clinical Innovation, Sylvester Comprehensive Cancer Center,
`University of Miami, Miami, Florida 2015–Present
`
`Medical Director Stem Cell Transplant Program, Sylvester Comprehensive Cancer
`Center, University of Miami, Miami, Florida 2008–Present
`
`IV.
`
`Publications
`
`Books and monographs published
`
`1. Kleiner G, Kritzer-Cheren M, Phillip Ruiz P, Komanduri KV, Lekakis L.
`2. Textbook: Transplantation Pathology: Pathology of Hematopoietic Stem Cell
`Transplantation, 2013.
`3. Lekakis L, Komanduri KV. Immunologic outcomes of allogeneic stem cell
`transplantation: graft-versus-host and graft-versus-leukemia responses and
`implications for future therapy, in Advances in tumor immunology and
`immunotherapy, 2013.
`4. Komanduri KV Gajewski J. Immune Reconstitution after Stem Cell Transplantation.
`In: Cellular Therapy: A Physician's Handbook. American Association of Blood Banks,
`2004.
`5. Komanduri KV McCune JM. Development and Reconstitution of T Lymphoid
`Immunity. In: Retroviral Immunology. Humana Press, 2001.
`6. Solomon S Komanduri KV. The Immune System. In: Biotherapy: A Comprehensive
`Overview. Jones and Bartlett, 38-63, 2000.
`
`Juried or refereed journal articles or exhibitions
`
`1. Neelapu SS, Locke FL, Bartlett NL, Lekakis LJ, Miklos DB, Jacobson
`CA, Braunschweig I, Oluwole OO, Siddiqi T, Lin Y, Timmerman JM, Stiff
`PJ, Friedberg JW, Flinn IW, Goy A, Hill BT, Smith MR, Deol A, Farooq
`U, McSweeney P, Munoz J, Avivi I, Castro JE, Westin JR, Chavez JC, Ghobadi
`A, Komanduri KV, Levy R, Jacobsen ED, Witzig TE, Reagan P, Bot A, Rossi
`J, Navale L, Jiang Y, Aycock J, Elias M, Chang D, Wiezorek J, Go WY.
`Axicabtagene Ciloleucel CAR T-Cell Therapy in Refractory Large B-Cell Lymphoma.
`N Engl J Med. 2017 Dec 28;377(26):2531-2544. doi: 10.1056/NEJMoa1707447.
`Epub 2017 Dec 10.
`2. Malpica L, Pimentel A, Reis IM, Gotuzzo E, Lekakis L, Komanduri K, Harrington
`T, Barber GN, Ramos JC. Epidemiology, clinical features, and outcome of HTLV-1-
`related ATLL in an area of prevalence in the United States. Blood Adv. 2018 Mar
`27;2(6):607-620. doi: 10.1182/bloodadvances.2017011106.
`3. Jones RB, Martinez C, Majhail NS, Prestegaard M, Maiers M, Horwitz M, Komanduri
`K. Stem Cell Transplantation and Informatics: Current Considerations. Biol Blood
`Marrow Transplant. 2017 Dec 27. pii: S1083-8791(17)31822-0. doi:
`10.1016/j.bbmt.2017.12.792.
`4. Camargo JF, Kimble E, Rosa R, Shimose LA, Bueno MX, Jeyakumar N, Morris
`MI, Abbo LM, Simkins J, Alencar MC, Benjamin C, Wieder E, Jimenez A, Beitinjaneh
`A, Goodman M, Byrnes JJ, Lekakis LJ, Pereira D, Komanduri KV. Impact of
`Cytomegalovirus Viral Load on Probability of Spontaneous Clearance and Response
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`to Preemptive Therapy in Allogeneic Stem Cell Transplantation Recipients. Biol
`Blood Marrow Transplant. 2017 Dec 5. pii: S1083-8791(17)30885-6. doi:
`10.1016/j.bbmt.2017.11.038
`5. Gajewski JL, McClellan MB, Majhail NS, Hari PN, Bredeson CN, Maziarz
`RT, LeMaistre CF, Lill MC, Farnia SH, Komanduri KV, Boo MJ. Payment and Care
`for Hematopoietic Cell Transplantation Patients: Toward a Specialized Medical
`Home for Complex Care Patients. Biol Blood Marrow Transplant. 2018 Jan;24(1):4-
`12. doi: 10.1016/j.bbmt.2017.09.012. Epub 2017 Sep 28.
`6. Neelapu SS, Tummala S, Kebriaei P, Wierda W, Gutierrez C, Locke FL, Komanduri
`KV, Lin Y, Jain N, Daver N, Westin J, Gulbis AM, Loghin ME, de Groot JF, Adkins
`S, Davis SE, Rezvani K, Hwu P, Shpall EJ. Chimeric antigen receptor T-cell therapy
`- assessment and management of toxicities. Nat Rev Clin Oncol. 2018 Jan;15(1):47-
`62. doi: 10.1038/nrclinonc.2017.148. Epub 2017 Sep 19.
`7. Camargo JF, Komanduri KV. Emerging concepts in cytomegalovirus infection
`following hematopoietic stem cell transplantation. Hematol Oncol Stem Cell
`Ther. 2017 Dec;10(4):233-238. doi: 10.1016/j.hemonc.2017.05.001. Epub 2017 Jun
`14.
`8. Wolf D, Barreras H, Bader CS, Copsel S, Lightbourn CO, Pfeiffer BJ, Altman
`NH, Podack ER, Komanduri KV, Levy RB. Marked in Vivo Donor Regulatory T Cell
`Expansion via Interleukin-2 and TL1A-Ig Stimulation Ameliorates Graft-versus-Host
`Disease but Preserves Graft-versus-Leukemia in Recipients after Hematopoietic
`Stem Cell Transplantation. Biol Blood Marrow Transplant. 2017 May;23(5):757-766.
`doi: 10.1016/j.bbmt.2017.02.013. Epub 2017 Feb 20.
`9. Khushman M, Morris MI, Diaz L, Goodman M, Pereira D, Fuller K, Garcia-Buitrago
`M, Moshiree B, Zelaya S, Nayer 7, Benjamin CL, Komanduri KV. Syndrome of
`Inappropriate Anti-Diuretic Hormone Secretion Secondary to Strongyloides
`stercoralis Infection in an Allogeneic Stem Cell Transplant Patient: A Case Report
`and Literature Review. Transplant Proc. 2017 Mar;49(2):373-377. doi:
`10.1016/j.transproceed.2016.12.012.
`10. Qazilbash MH, Wieder E, Thall PF, Wang X, Rios R, Lu S, Kanodia S, Ruisaard KE,
`Giralt SA, Estey EH, Cortes J, Komanduri KV, Clise-Dwyer K, Alatrash G, Ma Q,
`Champlin RE, Molldrem JJ. PR1 peptide vaccine induces specific immunity with
`clinical responses in myeloid malignancies. Leukemia. 2017. 31:3, 697-704.
`11. Camargo JF, Morris MI, Abbo LM, Simkins J, Saneeymehri S, Alencar MC, Lekakis
`LJ, Komanduri KV. The use of brincidofovir for the treatment of mixed dsDNA viral
`infection. Journal of Clinical Virology. 2016. 83: 1-4.
`12. Perez VL, Barsam A, Duffort S, Urbieta M, Barreras H, Lightbourn C, Komanduri KV,
`Levy RB. Novel Scoring Criteria for the Evaluation of Ocular Graft-versus-Host
`Disease in a Preclinical Allogeneic Hematopoietic Stem Cell Transplantation Animal
`Model.Biology of Blood and Marrow Transplantation. 2016. 22(10): 1765-1772.
`13. Benjamin CL, Stowe RP, St. John L, Sams CF, Mehta SK, Crucian BE, Pierson DL,
`Komanduri KV. Decreases in thymopoiesis of astronauts returning from space flight.
`JCI Insight. 2016;1(12):e88787. doi:10.1172/jci.insight.88787
`14. Itamura H, Shindo T, Tawara I, Kubota Y, Kariya R, Okada S, Komanduri KV, Kimura
`S. The MEK inhibitor trametinib separates murine graft-versus-host disease from
`graft-versus-tumor effects JCI Insight. 2016;1(10):e86331.
`doi:10.1172/jci.insight.86331.
`15. Ballen K, Woo Ahn K, Chen M, Abdel-Azim H, Ahmed I, Aljurf M, Antin J, Bhatt AS,
`Boeckh M, Chen G, Dandoy C, George B, Laughlin MJ, Lazarus HM, MacMillan ML,
`Margolis DA, Marks DI, Norkin M, Rosenthal J, Saad A, Savani B, Schouten HC,
`Storek J, Szabolcs P, Ustun C, Verneris MR, Waller EK, Weisdorf DJ, Williams KM,
`Wingard JR, Wirk B, Wolfs T, Young JH, Auletta J, Komanduri KV, Lindemans C,
`Riches ML. Infection Rates among Acute Leukemia Patients Receiving Alternative
`Donor Hematopoietic Cell Transplantation. Biol Blood Marrow Transplant. 2016 Jun
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`22. pii: S1083-8791(16)30147-1. doi: 10.1016/j.bbmt.2016.06.012. [Epub ahead
`ofprint] PubMed PMID: 27343716.
`16. Barba P, Burns LJ, Litzow MR, Juckett MB, Komanduri KV, Lee SJ, Devlin SM,
`Costa LJ, Khan S, King A, Klein A, Krishnan A, Malone A, Mir MA, Moravec C, Selby
`G, Roy V, Cochran M, Stricherz MK, Westmoreland MD, Perales MA, Wood WA;
`American Society for Blood and Marrow Transplantation Committee on Education.
`Success of an International Learning Health Care System in Hematopoietic Cell
`Transplantation: The American Society of Blood and Marrow Transplantation Clinical
`Case Forum. Biol Blood Marrow Transplant. 2016 Mar;22(3):564-70. doi:
`10.1016/j.bbmt.2015.12.008. Epub 2015 Dec 21. PubMed PMID: 26718665;
`PubMed Central PMCID: PMC4965270.
`17. Komanduri KV, Levine RL. Diagnosis and Therapy of Acute Myeloid Leukemia in the
`Era of Molecular Risk Stratification. Annu Rev Med. 2016;67:59-72. doi:
`10.1146/annurev-med-051914-021329. Epub 2015 Oct 16. PubMed PMID:
`26473413.
`18. Komanduri KV. A maturing understanding of naive T cells. Blood. 125(18):2742-3,
`19. 4/2015. PMID: 25931580
`20. Herretes S, Ross DB, Duffort S, Barreras H, Yaohong T, Saeed AM, Murillo JC,
`Komanduri KV, Levy RB, Perez VL. Recruitment of Donor T Cells to the Eyes during
`Ocular GVHD in Recipients of MHC-Matched Allogeneic Hematopoietic Stem Cell
`Transplants. Invest Ophthalmol Vis Sci. 56(4):2348-57, 4/2015. PMID: 25655798
`PMCID: PMC4406104.
`21. Komanduri KV, Veys P. Selected Reviews from the 2015 BMT Tandem Meetings.
`Biol Blood Marrow Transplant. 21(2 Suppl):S1-2, 2/2015. PMID: 25534537.
`22. Maziarz RT, Farnia S, Martin P, Komanduri KV. Optimal benefits for
`23. hematopoietic stem cell transplantation: a consensus opinion. Biol Blood Marrow
`Transplant. 20(11):1671-6,11/2014. PMID: 25020102.
`24. Parikh SH, Mendizabal A, Benjamin CL, Komanduri KV, Antony J, Petrovic A, Hale
`G, Driscoll TA, Martin PL, Page K, Flickinger K, Moffet J, Niedzwiecki D, Kurtzberg J,
`Szabolcs P. A novel reduced intensity conditioning regimen for unrelated umbilical
`cord blood transplantation in children with non-malignant diseases. Biol Blood
`Marrow Transplant. 2013 Nov 29. doi:pii: S1083-8791(13)00558-2.
`10.1016/j.bbmt.2013.11.021.
`25. Newman RG, Ross DB, Barreras H, Herretes S, Podack ER, Komanduri KV, Perez
`VL, Levy RB. The allure and peril of hematopoietic stem cell transplantation:
`overcoming immune challenges to improve success. Immunol Res. 57(1-3):125-39,
`12/2013. PMID: 24272856.
`26. Komanduri KV, Wieder ED, Benjamin CL, Levy RB. The evolving art of
`hematopoietic stem cell transplantation: translational research in post-transplant
`immune reconstitution and immunosuppression. Immunol Res. 57(1-3):140-50,
`12/2013. PMID: 24242818.
`27. Díaz-Montero CM, Zidan AA, Pallin MF, Anagnostopoulos V, Salem ML, Wieder E,
`Komanduri K, Montero AJ, Lichtenheld MG. Understanding the biology of ex vivo-
`expanded CD8 T cells for adoptive cell therapy: role of CD62L. Immunol Res. 57(1-
`3):23-33, 12/2013. PMID: 24218360.
`28. Ross D, Jones M, Komanduri K, Levy RB. Antigen and lymphopenia-driven donor T
`cells are differentially diminished by post-transplantation administration of
`cyclophosphamide after hematopoietic cell transplantation. Biol Blood Marrow
`Transplant. 19(10):1430-8, 10/2013. PMID: 23819914.
`29. Shindo T, Kim TK, Benjamin CL, Wieder ED, Levy RB, Komanduri KV. MEK
`inhibitors selectively suppress alloreactivity and graft-versus-host disease in a
`memory stage-dependent manner. Blood.121(23):4617-26, 6/2013. PMID:
`23575444 PMCID: PMC3674663.
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`30. Komanduri KV. Targeting neovascularization in GVHD. Blood. 121(17):3303-4,
`4/2013. PMID: 23620570.
`31. Vence LM, Wang C, Pappu H, Anson RE, Patel TA, Miller P, Bassett R, Lizee G,
`Overwijk WW, Komanduri K, Benjamin C, Alvarado G, Patel SP, Kim K,
`Papadopoulos NE, Bedikian AY, Homsi J, Hwu WJ, Boyd R, Radvanyi L, Hwu P.
`Chemical Castration of Melanoma Patients Does Not Increase the Frequency of
`Tumor-specific CD4 and CD8 T Cells After Peptide Vaccination. J Immunother.
`36(4):276-86, 5/2013. PMID: 23603862 PMCID: PMC3799876.
`32. Komanduri KV. Pharmacists and physicians in hematopoietic stem cell
`transplantation: advances and opportunities to utilize collaborative practice
`agreements to improve care. Biol Blood Marrow Transplant. Biol Blood Marrow
`Transplant. 19(4):505-6, 4/2013. PMID: 23416093.
`33. Khan S, Juckett MB, Komanduri KV, Krishnan A, Burns LJ. American Society of
`Blood and Marrow Transplantation: Guidelines for Training in Hematopoietic
`Progenitor Cell Transplantation. Biol Blood Marrow Transplant. 18(9):1322-8,
`9/2012. PMID: 22522027.
`34. Joseph RW, Bayraktar UD, Kim TK, John LS, Popat U, Khalili J, Molldrem JJ, Wieder
`ED, Komanduri KV. Vitamin D receptor upregulation in alloreactive human T cells.
`Hum Immunol. 73(7):693-8, 7/2012. PMID: 22548720.
`35. Komanduri KV. GVHD Protection? ThiNK iNKT cells. Blood. 120(10):1972-3,
`9/2012. PMID: 22956529.
`36. Komanduri KV, Champlin RE. Can Treg therapy prevent GVHD? Blood. 2011 Jan
`20;117(3):751-2, 1/2011. PMID: 21252098.
`37. Díaz-Montero CM, Naga O, Zidan AA, Salem ML, Pallin M, Parmigiani A, Walker G,
`Wieder E, Komanduri K, Cole DJ, Montero AJ, Lichtenheld MG. Synergy of brief
`activation of CD8 T-cells in the presence of IL-12 and adoptive transfer into
`lymphopenic hosts promotes tumor clearance and anti-tumor memory. Am J Cancer
`Res. 30;1(7): 882-896, 8/2011. PMID: 21915391 PMCID: PMC3170749.
`38. Bayraktar UD, Kim TK, Drews-Elger K, Benjamin C, El-Ashry D, Wieder E,
`Komanduri KV. Simultaneous Measurement of ERα, HER2, and PhosphoERK1/2 in
`Breast Cancer Cell Lines by Flow Cytometry. Breast Cancer Res Treat. 129(2):623-
`8, 9/2011. PMID: 21607585.
`39. Joseph RW, Alousi A, Konda B, Komanduri K, Neumann J, Trevino C, Stolar K,
`Qazibash M, Hosing C, Kebriaei P, Couriel DR, Champlin RE, Saliba R, Popat U.
`High incidence of vitamin D deficiency in patients undergoing allogeneic stem cell
`transplantation. Am J Hematol. 86(11):954-6, 11/2011. PMID: 21948087.
`40. Li D, Li Y, Hernandez JA, Patenia R, Kim TK, Khalili J, Dougherty MC, Hanley PJ,
`Bollard CM, Komanduri KV, Hwu P, Champlin RE, Radvanyi LG, Molldrem JJ, Ma Q.
`Lovastatin Inhibits T-cell Proliferation While Preserving the Cytolytic Function of
`EBV, CMV, and MART-1-specific CTLs. J Immunother. 33(9):975-82, 11-12/2010.
`PMID: 20948439.
`41. Carreño R, Brown WS, Li D, Hernandez JA, Wang Y, Kim TK, Craft JW Jr,
`Komanduri KV, Radvanyi LG, Hwu P, Molldrem JJ, Legge GB, McIntyre BW, Ma Q.
`2E8 binds to the high affinity I-domain in a metal ion-dependent manner: a second
`generation monoclonal antibody selective targeting activated LFA-1. J Biol Chem.
`285(43):32860-8, 10/2010. PMID: 20724473 PMCID: PMC2963386.
`42. de Lima M, Giralt S, Thall PF, de Padua Silva L, Jones RB, Komanduri KV, Braun
`TM, Nguyen HQ, Champlin R, Garcia-Manero G. Maintenance therapy with low-dose
`azacitidine after allogeneic hematopoietic stem cell transplantation for recurrent
`acute myelogenous leukemia or myelodysplastic syndrome: a dose and schedule
`finding study. Cancer. 116(23):5420-31, 12/2010. PMID: 20672358.
`43. Escalon ME, Komanduri KV. Cord blood transplantation: evolving strategies to
`improve engraftment and immune reconstitution. Curr Opin Oncol. 22(2):122-9,
`3/2010. PMID: 20180284.
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`44. Kim TK, Billard MJ, Wieder ED, McIntyre WB, Komanduri KV. Co-engagement of
`alpha(4)beta(1) integrin (VLA-4) and CD4 or CD8 is necessary to induce maximal
`Erk1/2 phosphorylation and cytokine production in human T cells. Hum Immunol.
`2010 Jan;71(1):23-8. PMID: 19815047 PMCID: PMC2795106.
`45. Wang Y, Li D, Jones D, Bassett R, Sale GE, Khalili J, Komanduri KV, Couriel DR,
`Champlin RE, Molldrem JJ, Ma Q. Blocking LFA-1 activation with lovastatin prevents
`graft-versus-host disease in mouse bone marrow transplantation. Biol Blood Marrow
`Transplant. 15(12):1513-22,12/2009. PMID: 19896074.
`46. Kim TK, St John LS, Wieder ED, Khalili J, Ma Q, Komanduri KV. Human late
`memory CD8+ T cells have a distinct cytokine signature characterized by CC
`chemokine production without IL-2 production. J Immunol. 183(10):6167-74,
`11/2009. PMID: 19841187.
`47. Decker WK, Xing D, Li S, Robinson SN, Yang H, Steiner D, Komanduri KV, Shpall
`EJ. Th-1 polarization is regulated by dendritic cell comparison of MHC class I and
`class II antigens. Blood. 113(18):4213-23, 4/2009. PMID: 19171878 PMCID:
`PMC2676083
`48. Joseph RW, Couriel DR, Komanduri KV. Chronic graft-versus-host disease after
`allogeneic stem cell transplantation: challenges in prevention, science and
`supportive care. J Support Oncol. 6(8):361-72, 11-12/2008. PMID: 19149321
`49. Saliba RM, Komanduri KV, Giralt S, de Souza J, Patah P, Oran B, Couriel D,
`Rondon G, Champlin RE, de Lima M. Leukemia burden delays lymphocyte and
`platelet recovery after allo-SCT for AML. Bone Marrow Transplant. 43(9):685-92,
`5/2009. PMID: 19011667 PMCID: PMC4038152.
`50. Komanduri KV, GVHD therapy: let there be light! Blood 112(4):932-3, 8/2008. PMID:
`18684879.
`51. Decker WK, Li S, Xing D. Robinson SN, Yan H, Steiner D, Komanduri KV, Bollard
`CM, Shpall Ej. Deficient T(H)-1 responses from TNF-alpha-matured and alpha-
`CD40-matured dendritic cells. J Immunother. 31(2):157-65, 2-3/2008. PMID:
`18481385.
`52. de Lima M, McMannis J, Gee A, Komanduri K, Couriel D, Andersson BS, Hosing C,
`Khouri I, Jones R, Champlin R, Karandish S, Sadeghi T, Peled T, Grynspan F,
`Daniely Y, Nagler A, Shpall EJ. Transplantation of ex vivo expanded cord blood cells
`using the copper chelator tetraethylenepentamine: a phase I/II clinical trial. Bone
`Marrow Transplant. 41(9):771-8, 5/2008. PMID: 18209724 PMCID: PMC4086223
`53. Bashoura L, Gupta S, Jain A, Couriel DR, Komanduri KV, Eapen GA, Safdar A,
`Broglio KR, Adachi R, Dickey BF. Inhaled corticosteroids stabilize constrictive
`bronchiolitis after hematopoietic stem cell transplantation. Bone Marrow Transplant
`41(1):63-7, 1/2008. PMID: 17934530.
`54. Gress RE, Komanduri KV, Einsele H, Cooper LJ. Lymphoid reconstruction and
`vaccines. Biol Blood Marrow Transplant.13(1 Suppl 1):17-22, 1/2007. PMID:
`17222765 PMCID: PMC1858644.
`55. Komanduri KV, St John LS, de Lima M, McMannis J, Rosinski S, McNiece I, Bryan
`SG, Kaur I, Martin S, Wieder ED, Worth L, Cooper LJ, Petropoulos D, Molldrem JJ,
`Champlin RE, Shpall EJ. Delayed immune reconstitution after cord blood
`transplantation is characterized by impaired thymopoiesis and late memory T cell
`skewing. Blood. 110(13):4543-51,12/2007. PMID: 17671230 PMCID: PMC2234787
`56. Ozdemir E, Saliba RM, Champlin RE, Couriel DR, Giralt SA, de Lima M, Khouri IF,
`Hosing C, Kornblau SM, Anderlini P, Shpall EJ, Qazilbash MH, Molldrem JJ,
`Chemaly RF, Komanduri KV. Risk factors associated with late cytomegalovirus
`reactivation after allogeneic stem cell transplantation for hematological malignancies.
`Bone Marrow Transplantation 40(2):125-136, 7/2007. PMID: 17530009.
`57. Orciuolo E, Stanzani M, Canestraro M, Galimberti S, Carulli G, Lewis R, Petrini M,
`Komanduri KV. Effects of Aspergillus fumigatus gliotoxin and methylprednisolone on
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`human neutrophils: implications for the pathogenesis of invasive aspergillosis. J
`Leukoc Biol. 82(4):839-48, 10/2007. PMID: 17626149.
`58. Komanduri KV, Couriel D, Champlin RE. Graft-versus-host disease after allogeneic
`stem cell transplantation: evolving concepts and novel therapies including
`photopheresis. Biol Blood Marrow Transplant 12(1 Suppl 2):1-6, 1/2006. PMID:
`16399595.
`59. Parmar S, Robinson SN, Komanduri K, St John L, Decker W, Xing D, Yang H,
`McMannis J, Champlin R, de Lima M, Molldrem J, Rieber A, Bonyhadi M, Berenson
`R, Shpall EJ. Ex vivo expanded umbilical cord blood T cells maintain naive
`phenotype and TCR diversity. Cytotherapy 8(2):149-57, 2006. PMID: 16698688.
`60. Xing D, Decker WK, Li S, Robinson SN, Yang H, Segal H, O'Connor S, Yao X,
`Komanduri KV, McMannis JD, Jones RB, de Lima M, Champlin RE, Shpall EJ. AML-
`loaded DC generate Th1-type cellular immune responses in vitro. Cytotherapy
`8(2):95-104, 2006. PMID: 16698683
`61. Decker WK, Xing D, Li S, Robinson SN, Yang H, Yao X, Segall H, McMannis JD,
`Komanduri KV, Champlin RE, Shpall EJ. Double loading of dendritic cell MHC class I
`and MHC class II with an AML antigen repertoire enhances correlates of T-cell
`immunity in vitro via amplification of T-cell help. Vaccine 24(16):3203-16, 4/2006.
`PMID: 16480795.
`62. Wong R, Shahjahan M, Wang X, Thall PF, de Lima M, Khouri I, Gajewski J, Alamo J,
`Couriel D, Andersson BS, Donato M, Hosing C, Komanduri K, Anderlini P, Molldrem
`JJ, Ueno NT, Estey E, Ippoliti C, Champlin RE, Giralt S. Prognostic Factors for
`Outcomes of Patients with Refractory or Relapsed Acute Myelogenous Leukemia or
`Myelodysplastic Syndromes Undergoing Allogeneic Progenitor Cell Transplantation.
`Biol Blood Marrow Transplant 11(2):108-14, 2/2005. PMID: 15682071.
`63. Lewis RE, Wiederhold NP, Chi J, Han XY, Komanduri KV, Kontoyiannis DP, Prince
`RA. Detection of gliotoxin in experimental and human aspergillosis. Infect Immun
`73(1):635-7, 1/2005. PMID: 15618207 PMCID: PMC538950.
`64. Stanzani M, Orciuolo E, Lewis R, Kontoyiannis DP, Martins SL, St John LS,
`Komanduri KV. Aspergillus fumigatus suppresses the human cellular immune
`response via gliotoxin-mediated apoptosis of monocytes. Blood 105(6):2258-65,
`3/2005. PMID: 15546954.
`65. Martins SL, St John LS, Champlin RE, Wieder ED, McMannis J, Molldrem JJ,
`Komanduri KV. Functional assessment and specific depletion of alloreactive human
`T cells using flow cytometry. Blood 104(12):3429-36, 12/2004. PMID: 15284108.
`66. Madoff DC, Wallace MJ, Lichtiger B, Komanduri KV, Ross WA, Narvios AB, Parmley
`CL. Intraarterial platelet infusion for patients with intractable gastrointestinal
`hemorrhage and severe refractory thrombocytopenia. J Vasc Interv Radiol
`15(4):393-7, 4/2004. PMID: 15064344.
`67. Stanzani M, Martins SL, Saliba RM, St John LS, Bryan S, Couriel D, McMannis J,
`Champlin RE, Molldrem JJ, Komanduri KV. CD25 expression on donor CD4+ or
`CD8+ T cells is associated with an increased risk for graft-versus-host disease after
`HLA-identical stem cell transplantation in humans. Blood 103(3):1140-6, 2/2004.
`PMID: 12907445
`68. Lu S, Wieder E, Komanduri KV, Ma Q, Molldrem JJ. Vaccines in Leukemia. Adv
`Pharmacol. 51:255-70, 2004. PMID: 15464913.
`69. Couriel D, Caldera Humberto, Champlin RE, Komanduri KV. Acute Graft-versus-Host
`Disease: Pathophysiology, Clinical Manifestations and Management. Cancer
`101(9):1936-46, 11/2004. PMID: 15372473
`70. Ozdemir E, St John LS, Gillespie G, Rowland-Jones S, Champlin RE, Molldrem JJ,
`Komanduri KV. Cytomegalovirus reactivation following allogeneic stem cell
`transplantation is associated with the presence of dysfunctional antigen-specific
`CD8+ T cells. Blood 100(10):3690-7, 11/2002. PMID: 12393402
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`71. de Lima M, St John LS, Wieder ED, Lee MS, McMannis J, Karandish S, Giralt S,
`Beran M, Couriel D, Korbling M, Bibawi S, Champlin R, Komanduri KV. Double-
`chimaerism after transplantation of two human leucocyte antigen mismatched,
`unrelated cord blood units. Br J Haematol 119(3):773-6, 12/2002. PMID: 12437658
`72. Molldrem JJ, Komanduri K, Wieder E. Overexpressed differentiation antigens as
`targets of graft-versus-leukemia reactions. Curr Opin Hematol. 2002 Nov;9(6):503-8
`11/2002. PMID: 12394172.
`73. Komanduri KV. Thymic function and allogeneic T-cell responses in stem-cell
`transplantation. Cytotherapy 4(4):333-42, 2002. PMID: 12396833.
`74. Komanduri KV, Feinberg J, Hutchins RK, Frame RD, Schmidt DK, Viswanathan MN,
`Lalezari JP, McCune JM. Loss of cytomegalovirus-specific CD4+ T cell responses in
`human immunodeficiency virus type 1-infected patients with high CD4+ T cell counts
`and recurrent retinitis. J Infect Dis 183(8):1285-9, 4/2001. PMID: 11262214.
`75. Komanduri KV, McCune JM. The diversity of T cells. N Engl J Med 344(3):231-2,
`1/2001. PMID: 11188843.
`76. Komanduri KV, Donahoe SM, Moretto WJ, Schmidt DK, Gillespie G, Ogg GS,
`Roederer M, Nixon DF, McCune JM. Direct measurement of CD4+ and CD8+ T-cell
`responses to CMV in HIV-1-infected subjects. Virology 279(2):459-70, 1/2001. PMID:
`11162802.
`77. Poulin JF, Viswanathan MN, Harris JM, Komanduri KV, Wieder E, Ringuette N,
`Jenkins M, McCune JM, Sekaly RP. Direct evidence for thymic function in adult
`humans. J Exp Med 190(4):479-86, 8/1999. PMID: 10449519 PMCID: PMC2195604.
`78. Komanduri KV, Viswanathan MN, Wieder ED, Schmidt DK, Bredt BM, Jacobson MA,
`McCune JM. Restoration of cytomegalovirus-specific CD4+ T-lymphocyte responses
`after ganciclovir and highly active antiretroviral therapy in individuals infected with
`HIV-1. Nat Med 4(8):953-6, 8/1998. PMID: 9701250
`79. Komanduri KV, Salha MD, Sekaly RP, McCune JM. Superantigen-mediated deletion
`of specific T cell receptor V beta subsets in the SCID-hu Thy/Liv mouse is induced
`by staphylococcal enterotoxin B, but not HIV-1. J Immunol 158(2):544-9, 1/1997.
`PMID: 8992966.
`80. Wang J, Huang M, Lee P, Komanduri KV, Sharma S, Chen G, Dubinett SM.
`Interleukin-8 inhibits non-small cell lung cancer proliferation: a possible role for
`regulation of tumor growth by autocrine and paracrine pathways. Journal of
`Interferon and Cytokine Research 16(1):53-60, 1996. PMID: 8640452.
`81. Komanduri KV, Luce JA, McGrath MS, Herndier BG, Ng VL. The natural history and
`molecular heterogeneity of HIV-associated primary malignant lymphomatous
`effusions. J Acquir Immune Defic Syndr Hum Retrovirol 13(3):215-26, 11/1996.
`PMID: 8898666.
`82. Mooradian DL, McCarthy JB, Komanduri KV, Furcht LT. Effects of transforming
`growth factor-beta 1 on human pulmonary adenocarcinoma cell adhesion, motility,
`and invasion in vitro. J Natl Cancer Inst 84(7):523-7, 4/1992. PMID: 1545442.
`
`Other works, publications and abstracts
`
`1. Edwards CG, Walters L, Lekakis LJ, Luis N, Benjamin CL, Chinquee D, Gomez P,
`Komanduri KV. Implementing Programmatic Changes Required for New Cellular
`Therapy Quality Standards and Data Registry Reporting. Biology of Blood and
`Marrow Transplantation , 2018 March. Volume 24 , Issue 3 , S127 - S128.
`2. Malone AK, Litzow MR, Perales MA, Costa LJ, Wood WA, Komanduri KV, Selby GB,
`Khan SP, Roy V, Domm J, Burns LJ. Should BMT Become a Certified Subspecialty?
`Results of the 2017 Board Certification Survey. Biology of Blood and Marrow
`Transplantation, 2018 March. Volume 24 , Issue 3 , S305 - S306
`3. Camargo JF, Wieder E, Kimble E, Benjamin CL, Kolonias D, Bravo G, Komanduri
`KV. Functional Signatures Revealed by Deep Phenotyping of CMV-Specific CD8+ T
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`Cells Predict Risk of Early CMV Reactivation after Allogeneic Hematopoietic Cell
`Transplantation. Biology of Blood and Marrow Transplantation, 2018 March. Volume
`24, Issue 3, S99
`4. Naik S, Kamble RT, Hari P, Kim S, Chen M, Komanduri KV, Lindemans CA, Auletta
`JJ, Riches ML. Outcomes of Allogeneic Hematopoietic Cell Transplants with EBV
`Positive or EBV Negative Post-Transplant Lymphoproliferative Disorder (PTLD).
`Biology of Blood and Marrow Transplantation, 2018 March. Volume 24, Issue 3,
`S370
`5. Abidi MZ, Chen M, Kim S, Auletta JJ, Lindemans CA, Komanduri KV, Riches ML.
`Viral Isolates in the Cerebrospinal Fluid of Hematopoietic Stem Cell Transplant
`Recipients, 2007-2015. Biology of Blood and Marrow Transplantation, 2018 March.
`Volume 24, Issue 3, S378
`6. Wang TP, Jimenez AM, Lekakis LJ, Pereira D, Goodman M, Ramos JC, Komanduri
`KV, Beitinjaneh A. Allogeneic Transplant for HTLV-1 Adult T-Cell Lymphoma-
`Leukemia. Biology of Blood and Marrow Transplantation, 2018 March. Volume 24,
`Issue 3, S342 - S343
`7. Gea-Banacloche, J; Komanduri, KV; Carpenter, P; Paczesny, S; Sarantopoulos, S;
`Young, JA; El Kassar, N; Le, RQ; Schultz, KR; Griffith, LM; Savani, BN; Wingard, JR.
`National Institutes of Health Hematopoietic Cell Transplantation Late Effects
`Initiative: The Immune Dysregulation and Pathobiology Working Group Report. Biol.
`Blood Marrow Transplant., 2017 vol. 23(6) pp. 870-881
`8. Rueda-Lara M, Barrera I, Amiel C, Lehardy E, Goldstein H, Fisher H, Antoni M,
`Komanduri KV.Neuropsychological and psychiatric functioning in Hispanic and non-
`Hispanic patients with cancer-seeking hematopoietic stem cell transplantation.
`Psycho-Oncology. 2017. 26: 86-86
`9. Wolf D, Barreras H, Bader C, Copsel S, Lightbourn C, Pfeiffer B, Podack ER,
`Komanduri KV, Levy RB. Marked in vivo Donor Treg expansion via targeting of the
`IL-2/CD25 and TL1A/TNFRSF25 pathways ameliorates GVHD and preserves
`GVL. Cytotherapy. 2017 May.19:5, S11–S12.
`10. Copsel S, Manov J, Lightbourn CO, Barreras H, Bader CS, Pfeiffer B, Shah D, Wolf
`D, Komanduri KV, Wahlestedt C, Levy RB. Epigenetic Regulation Together with Treg
`Expansion: A New Combinatorial Strategy for Application in Experimental Allogeneic
`HSCT. ASBMT Tandem Meetings. 2017;432.
`11. Camargo J, Kimble EL, Shimose L, Bueno M, Rosa R, Jeyakumar N, Morris M, Abbo
`LM, Simkins J, Alencar M, Benjamin CL, Wieder E, Jimenez A, Beitinjaneh A,
`Goodman M, Byrnes JJ, Lekakis LJ, Pereira D, Komanduri KV. Impact of
`Cytomegalovirus (CMV) Viral Load on Probability of Spontaneous Clearance and
`Efficacy of Pre-Emptive Therapy Among CMV Seropositive Allogeneic Stem Cell
`Transplant Recipients. ASBMT Tandem Meetings. 2017;221
`12. Papanicolaou GA, Ustun C, Young JH, Chen M, Kim S, Ahn KW, Auletta JJ,
`Lindemans CA, Komanduri KV, Riches ML. Impact of Early Bloodstream Infection
`(BSI) By Vancomycin-Resistant Enterococci (VRE) on Long-Term Transplant
`Outcomes. ASBMT Tandem Meetings. 2017;233
`13. Locke FL, Neelapu SS, Bartlett NL, Lekakis LJ, Miklos D, Jacobson CJ,
`Braunschweig I, Oluwole O, Siddiqi T, Lin Y, Timmerman