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`being affected by the remaining antimicrobial agent. Remedies for nail mycosis which can be obtained by the drug effect evaluation
`-- method as described above.
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`ARGENTUM EX1010
`
`Page 1
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`

`

`INTERNATIONAL SEARCH REPORT
`
`International application No.
`
`PCT/JP00/04617
`
`m.
`
`CLASSIFICATION OF SUBJECT MATTER
`Int. Clv C12QI/18, A61K31/454, A61P31/10,
`
`G01N33/15, G01N33/50
`
`According to International Patent Classification (IPC) or to both national classification and IPC
`
`B. FIELDS SEARCHED
`Minimum documentation searched (classification system followed by classification symbols)
`Int. Cl7 C12QI/18, A61K31/454, A61P31/10, G01N33/15, G01N33/50
`
`Documentation searched other than minimum documentation to the extent that such documents are included in the fields searched
`
`Electronic data base consulted during the international search (name of data base and, where practicable, search terms used)
`JICST FILE(JOIS)
`
`C.
`
`DOCUMENTSCONSIDEREDTO BE RELEVANT
`
`Category*
`
`x/Y
`
`Citationofdocument, withindication, whereappropfi~e, oftherelevantpassages
`JP, 8-i03291, A (Pola Chemical Industries Inc.),
`23 April, 1996 (23.04.96) (Family: none)
`
`JP, 10-28597, A (Gunze Limited),
`03 February, 1998 (03.02.98) (Family: none)
`
`Relevanttoclaim No.
`II,16/I-9,15
`
`1-9,15
`
`Y
`
`x
`
`WO, 94/26734, A1 (KAKEN PHARMACEUTICAL CO.,
`24 November, 1994 (24.11.94)
`& US, 5620994, A
`& EP, 698606, A1
`& US, 5962476, A
`& US, 5716969, A
`
`LTD.),
`
`i0,12-14,17
`
`[]
`
`Further documents are listed in the continuation of Box C. [] See patent family annex.
`
`*
`"A"
`
`"E"
`
`"L"
`
`"O"
`
`"P"
`
`Special categories of cited documents:
`document defining the general state of the art which is not
`considered to be of particular relevance
`earlier document but published on or after the international filing
`date
`document which may throw doubts on priority claim(s) or which is
`cited to establish the publication date of another citation or other
`special reason (as specified)
`document referring to an oral disclosure, use, exhibition or other
`means
`document published prior to the international filing date but later
`than the priority date claimed
`
`"T’
`
`"X"
`
`later document published after the international filing date or
`priority date and not in conflict with the application but cited to
`understand the principle or theory underlying the invention
`document of particular relevance; the claimed invention cannot be
`considered novel or cannot be considered to involve an inventive
`step when the document is taken alone
`document of particular relevance; the claimed invention cannot be
`considered to involve an inventive step when the document is
`combined with one or more other such documents, such
`combination being obvious to a person skilled in the art
`"&" document member of the same patent family
`
`"Y"
`
`Date of the actual completion of the international search
`14 September, 2000 (14.09.00)
`
`Date of mailing of the international search report
`
`03 October, 2000 (03.10.00)
`
`Name and mailing address of the ISA/
`Japanese Patent Office
`
`Facsimile No.
`
`Form PCT/ISA/210 (second sheet) (July 1992)
`
`Authorized officer
`
`Telephone No.
`
`Page 39
`
`

`

`INTERNATIONAL SEARCH REPORT
`
`I International application No.
`PCT/JP00/04617
`
`I
`
`Box 1 Observations where certain claims were found unsearchable (Continuation of item 1 of first sheet)
`
`This international search report has not been established in respect of certain claims under Article 17(2)(a) for the following reasons:
`
`1. [] Claims Nos.:
`because they relate to subject matter not required to be searched by this Authority, namely:
`
`2. [] Claims Nos.:
`because they relate to parts of the international application that do not comply with the prescribed requirements to such an
`extent that no meaningful international search can be carded out, specifically:
`
`3. [] Claims Nos.:
`because they are dependent claims and are not drafted in accordance with the second and third sentences of Rule 6.4(a).
`
`Boxll Obse~ationswhereuni~ofinventionislac~ng(Continuationofitem 2offirstsheet)
`
`ThisIntemationalSearchingAuthofity ~undmultipleinventionsinthisinternationalapplication, as~llows:
`Inventions as set forth in claims 1 to i0 and 15 to 17 pertain to a method for
`detecting a pathogenic microorganism; a method for evaluating the drug effect
`of an antimicrobial agent which comprises detecting a pathogenic microorganism
`by the method for detecting a pathogenic microorganism; and antimicrobial agents
`obtained by the drug effect evaluation method.
`Inventions as set forth in claims 12 to 14 pertain to remedies for nail mycosis
`having a specific structure.
`
`These two groups of inventions have no idea in common based on a technical
`matter. Such being the case, these two groups of inventions, which are different
`from each other, do not have any technical relevancy to each other in the meaning
`as specified in Rule 13.2 of the Regulations under the PCT.
`
`[] As all required additional search feeswere timely paid by the applicant, this international search report covers all searchable
`claims.
`
`2.
`
`[] As all searchable claims could be searched without effort justifying an additional fee, this Authority did not invite payment
`of any additional fee.
`
`[] As only some of the required additi°nal search fees were timely paid by the applicant’ this internati°nal search rep°rt c°vers
`only those claims for which fees were paid, specifically claims Nos.:
`
`4. [] No required additional search fees were timely paid by the applicant. Consequently, this international
`search report is restricted to the invention first mentioned in the claims; it is covered by claims Nos.:
`
`Remark on Protest [] The additional search fees were accompanied by the applicant’s protest.
`
`] No protes