(12) U nited States Patent
`Say et al.
`
`US006175752B1
`(io) Patent No.:
`US 6,175,752 B1
`(45) Date of Patent:
`Jan. 16,2001
`
`(54) ANALYTE MONITORING DEVICE AND
`METHODS OF USE
`
`(75)
`
`Inventors: James Say, Alameda; Michael F.
`Tomasco, Cupertino, both of CA (US);
`Adam Heller, Austin, TX (US); Yoram
`Gal, Kibbutz Yagur (IL); Behrad Aria,
`Alameda, CA (US); Ephraim Heller,
`Oakland, CA (US); Phillip John
`Plante, Sunnyvale, CA (US); Mark S.
`Vreeke, Alameda, CA (US); Keith A.
`Friedman, Austin, TX (US); Fredric
`C. Colman, Berkeley, CA (US)
`(73) Assignee: Therasense, Inc., Alameda, CA (US)
`( * ) Notice:
`Under 35 U.S.C. 154(b), the term of this
`patent shall be extended for 0 days.
`
`(21) Appl. No.: 09/070,677
`Apr. 30, 1998
`(22) Filed:
`
`(51)
`
`Int. C l.
`
`.................................................... A61B 5/05
`
`(52) U.S. Cl............................ 600/345; 600/365; 128/903
`
`(58) Field of Search .................................. 600/300-301,
`600/346, 306-309, 345-365, 372, 385-390;
`604/174-180; 128/897-898, 903, 904, 920
`
`(56)
`
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`Primary Examiner—Cary O’Connor
`Assistant Examiner—Michael Astorino
`(74) Attorney, Agent, or Firm—Merchant & Gould PC.
`(57)
`
`ABSTRACT
`
`An analyte monitor includes a sensor, a sensor control unit,
`and a display unit. The sensor has, for example, a substrate,
`a recessed channel formed in the substrate, and conductive
`material disposed in the recessed channel to form a working
`electrode. The sensor control unit typically has a housing
`adapted for placement on skin and is adapted to receive a
`portion of an electrochemical sensor. The sensor control unit
`also includes two or more conductive contacts disposed on
`the housing and configured for coupling to two or more
`contact pads on the sensor. A transmitter is disposed in the
`housing and coupled to the plurality of conductive contacts
`for transmitting data obtained using the sensor. The display
`unit has a receiver for receiving data transmitted by the
`transmitter of the sensor control unit and a display coupled
`to the receiver for displaying an indication of a level of an
`analyte. The analyte monitor may also be part of a drug
`delivery system to alter the level of the analyte based on the
`data obtained using the sensor.
`
`94 Claims, 26 Drawing Sheets
`
`SENSOR
`
`Dexcom Inc. v. WaveForm Technologies, Inc.
`IPR2017-01051
`Exhibit 1022
`
`

`

`US 6,175,752 B1
`Page 2
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`
`Dexcom Inc. v. WaveForm Technologies, Inc.
`IPR2017-01051
`Exhibit 1022
`
`

`

`US 6,175,752 B1
`Page 3
`
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`
`Dexcom Inc. v. WaveForm Technologies, Inc.
`IPR2017-01051
`Exhibit 1022
`
`

`

`US 6,175,752 B1
`Page 4
`
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`Exhibit 1022
`
`

`

`US 6,175,752 B1
`Page 5
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`Dexcom Inc. v. WaveForm Technologies, Inc.
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`Exhibit 1022
`
`

`

`US 6,175,752 B1
`Page 6
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`Dexcom Inc. v. WaveForm Technologies, Inc.
`IPR2017-01051
`Exhibit 1022
`
`

`

`US 6,175,752 B1
`Page 7
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