`SCIENTIFIC DIRECTOR & FELLOW at Janssen, Pharmaceutical Companies of Johnson and Johnson
`
`Summary
`A well-rounded Pharmacologist /Preclinical Development Scientist with a proven track record of advancing
` ligands targeting GPCRs, Ion Channels, Nuclear Hormone Receptors and Enzymes from concept to clinic in
` Metabolic Diseases, Inflammation/ Pain, Neuroscience, Autoimmune Diseases, and Oncology. Expertise in
` Pharmacology/Physiology, ADME/PK; clinical pharmacology, Safety Pharm, IND-enabling GLP studies &
` Managing CRO’s and outsourcing US/China).
`
`Successful track record of drug-hunting reflected in multiple INDs. Team work, collaboration and productivity
` reflected in more than 90 Peer-reviewed original research publications.
`
`Specialties: Pharmacology & Preclinical Development
`Therapeutic Areas: Inflammation, Autoimmune Diseases, Metabolic Diseases, Neuroscience and Oncology,
` Pharmacokinetics (non-clinical and clinical)
`
`Experience
`SCIENTIFIC DIRECTOR & FELLOW at Janssen, Pharmaceutical Companies of Johnson and Johnson
`2012 - Present
`
`Research Fellow, Pharmacology at Johnson and Johnson
`2009 - June 2012 (3 years 5 months)
`Leading a team of researchers focusing on Pharmacology of Autoimmune and Respiratory Diseases
`
`Director, Pharmacology & Preclin Dev at Kalypsys Inc
`2003 - September 2009 (6 years 8 months)
`Built Pharmacology & Preclinical Development Functions
`in support of advancement of leads in Met Dis, Inflammation and Oncology programs to Development. Key
` member of therapeutic area strategy & portfolio management.
`www.kalypsys.com
`
`Senior Research Fellow at Merck
`1998 - 2003 (5 years)
`Co-directed Multiple Sclerosis Project and successfully built multi-site collaborations in support of
` Neuroinflammation Therapeutic Area
`Key Member of the Neurodegeneration Team at MRL
`
`Associate Director
`
`Page 1
`
`Apotex v. Novartis
`IPR2017-00854
`NOVARTIS 2013
`
`
`
`1993 - 1998 (5 years)
`Built Pharmacology /DMPK functions in support of multiple programs; initiated Pain & Neurodegeneration
` efforts. Two nAChR agonists advanced to clinic: SIB-1508Y[Altinicline] for Parkinson's disease (AD) and
` SIB-1553A for Alzheimer's disease (AD).
`
`Research Scientist
`1988 - 1993 (5 years)
`Built a pharmacology lab to support Inflammation research focused on several eicsonoid and leukotriene
` targets &. CNS research focused on excitatory amino acid receptors. Applications of Mass Spectrometry for
` early ADME-PK and pharmacology.
`
`Visiting Scientist at Ciba-Geigy
`1987 - 1988 (1 year)
`Post-doctoral Visiting Scientist
`Excitatory Amino Acid Receptor Pharmacology
`Applications of Mass Spectrometry & microdialysis for studying change in neurotransmitter dynamics
`
`Formulation Development Scientist
`1982 - 1983 (1 year)
`Formulation Research (Parenteral and oral dose formulations) and Post-market stability
`
`Education
`University of Alberta
`PhD, Neuroscience, 1983 - 1986
`Andhra University
`M. Pharm, Pharmaceutics, 1980 - 1982
`Andhra University
`B. Pharm., Phamacy, 1975 - 1979
`
`Page 2
`
`
`
`Tadimeti S Rao
`SCIENTIFIC DIRECTOR & FELLOW at Janssen, Pharmaceutical Companies of Johnson and Johnson
`
`Contact Tadimeti S on LinkedIn
`
`Page 3
`
`
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