®
`
`Voice of the Pharmacist
`
`Source: SDI’s Vector One®: National
`2010 Top 200 generic drugs by total prescriptions
`
`Drug
`
`Rank
`
`Drug
`
`1
`2
`3
`4
`5
`6
`7
`8
`9
`10
`11
`12
`13
`14
`15
`16
`17
`18
`19
`20
`21
`22
`23
`24
`25
`26
`27
`28
`29
`30
`31
`32
`33
`34
`35
`
`Hydrocodone/APAP
`Lisinopril
`Simvastatin
`Levothyroxine
`Amoxicillin
`Amlodipine besylate
`Azithromycin
`Alprazolam
`Hydrochlorothiazide
`Omeprazole
`Metformin
`Furosemide oral
`Metoprolol tartrate
`Atenolol
`Sertraline
`Metoprolol succinate
`Zolpidem tartrate
`Oxycodone/APAP
`Citalopram HBR
`Gabapentin
`Ibuprofen
`Prednisone oral
`Tramadol
`Lisinopril/HCTZ
`Fluoxetine
`Lorazepam
`Warfarin
`Clonazepam
`Fluticasone nasal
`Cyclobenzaprine
`Cephalexin
`Trimethoprim/sulfa
`Fexofenadine
`Amoxicillin/pot clav
`Ciprofloxacin HCl
`
`Total
`Rxs
`122,806,850
`76,901,813
`76,771,821
`68,222,152
`51,083,822
`50,186,652
`48,756,188
`46,201,182
`45,838,017
`44,795,175
`41,932,689
`36,583,895
`34,707,807
`33,839,806
`33,409,838
`32,224,000
`29,719,569
`28,705,243
`27,993,635
`26,865,557
`26,256,548
`25,529,463
`25,527,796
`24,538,247
`24,473,994
`23,428,627
`23,388,338
`23,085,065
`22,447,832
`22,240,071
`21,943,482
`21,345,723
`20,430,430
`20,234,873
`20,063,382
`
`% Change from
`previous year
`2.1%
`4.3%
`4.9%
`8.2%
`-0.6%
`11.7%
`-2.1%
`3.9%
`-0.8%
`15.4%
`4.7%
`-0.1%
`-0.5%
`-11.0%
`8.9%
`12.0%
`-2.8%
`6.8%
`9.4%
`14.0%
`3.2%
`-2.7%
`10.3%
`8.0%
`6.8%
`3.7%
`1.5%
`4.0%
`19.7%
`7.3%
`2.7%
`4.5%
`27.5%
`1.2%
`1.8%
`
`Rank
`
`36
`37
`38
`39
`40
`41
`42
`43
`44
`45
`46
`47
`48
`49
`50
`51
`52
`53
`54
`55
`56
`57
`58
`59
`60
`61
`62
`63
`64
`65
`66
`67
`68
`69
`70
`
`1 Drug topicS
`
` June 2011
`
`Total
`Rxs
`Pravastatin
`20,026,786
`Trazodone HCl
`18,786,495
`Lovastatin
`17,509,951
`Triamterene/HCTZ
`17,201,037
`Carvedilol
`16,681,336
`Alendronate
`16,177,014
`Ranitidine HCl
`14,699,414
`Meloxicam
`14,645,167
`Diazepam
`14,584,147
`Naproxen
`14,297,759
`Propoxyphene-N/APAP
`14,274,354
`Fluconazole
`13,938,887
`Methylprednisolone tabs
`13,659,852
`Doxycycline
`13,199,430
`Paroxetine
`12,979,366
`Oxycodone
`12,652,375
`Clonidine
`12,616,634
`Amitriptyline
`12,611,254
`Allopurinol
`12,550,481
`Enalapril
`12,437,886
`Carisoprodol
`12,392,709
`Acetaminophen/cod
`12,071,346
`Klor-Con
`11,295,270
`Pantoprazole
`11,226,359
`Potassium chloride
`10,807,528
`Temazepam
`10,517,270
`Promethazine tabs
`10,221,172
`Glimepiride
`9,652,940
`Albuterol nebulizer soln
`9,598,825
`Tamsulosin HCl
`9,447,070
`Folic acid
`9,376,016
`Spironolactone
`9,201,879
`Amlodipine besy benz
`9,125,151
`Amphetamine salt cmb
`8,760,281
`Metformin HCl ER
`8,461,949
`Exhibit 1080
`IPR2017-00807
`ARGENTUM
`
`% Change from
`previous year
`17.9%
`6.5%
`13.5%
`-7.0%
`8.3%
`-6.9%
`6.6%
`2.9%
`7.1%
`10.3%
`-18.7%
`4.6%
`11.3%
`1.9%
`-14.4%
`40.9%
`6.2%
`-1.7%
`1.2%
`3.4%
`2.9%
`-2.5%
`-12.0%
`-13.2%
`7.5%
`21.0%
`-0.4%
`9.5%
`5.0%
`NA
`4.2%
`4.1%
`-13.8%
`23.6%
`11.5%
`
`DrugTopics.com
`
`000001
`
`

`

`®
`
`Voice of the Pharmacist
`
`Source: SDI’s Vector One®: National
`2010 Top 200 generic drugs by total prescriptions
`
`Rank
`
`Drug
`
`71
`72
`73
`74
`75
`76
`77
`78
`79
`80
`81
`82
`83
`84
`85
`86
`87
`88
`89
`90
`91
`92
`93
`94
`95
`96
`97
`98
`99
`100
`101
`102
`103
`104
`105
`
`Triamcinolone acet top
`Digoxin
`Lamotrigine
`Cefdinir
`Diltiazem CD
`Benazepril
`Topiramate
`Isosorbide mononitrate
`Ramipril
`Risperidone
`Glyburide
`Penicillin VK
`Lansoprazole
`Clindamycin systemic
`Bupropion XL
`Metronidazole tabs
`Glipizide
`Divalproex sodium
`Tri-Sprintec
`Losartan potassium
`Potassium chloride ER
`Phentermine
`Mirtazapine
`Hydroxyzine
`Estradiol oral
`Valacyclovir HCl
`Diclofenac sodium SR
`Nitrofrntoin mono mcr
`Verapamil SR
`Venlafaxine ER
`Mupirocin
`Buspirone HCl
`Gemfibrozil
`Amphetamine salt cmb SR
`Ondansetron
`
`Total
`Rxs
`8,369,032
`8,313,642
`8,305,108
`8,155,254
`8,126,525
`8,089,219
`8,068,070
`7,992,732
`7,853,422
`7,731,095
`7,642,056
`7,502,009
`7,363,625
`7,362,874
`7,317,814
`7,281,884
`7,154,850
`7,083,542
`6,724,925
`6,688,158
`6,492,534
`6,403,366
`6,308,288
`6,284,114
`6,261,135
`6,248,479
`6,051,578
`5,755,420
`5,726,646
`5,526,132
`5,511,196
`5,468,280
`5,390,002
`5,378,625
`5,257,769
`
`% Change from
`previous year
`3.6%
`-1.4%
`12.1%
`-0.2%
`41.1%
`6.1%
`54.2%
`-4.4%
`-5.1%
`6.1%
`-0.8%
`0.8%
`867.2%
`4.1%
`33.9%
`6.7%
`-1.6%
`17.6%
`10.5%
`NA
`-3.1%
`7.0%
`8.1%
`4.5%
`4.7%
`>999
`2.4%
`1.9%
`-21.2%
`552.8%
`12.6%
`7.1%
`-6.9%
`60.8%
`42.8%
`
`Rank
`
`Drug
`
`106
`107
`108
`109
`110
`111
`112
`113
`114
`115
`116
`117
`118
`119
`120
`121
`122
`123
`124
`125
`126
`127
`128
`129
`130
`131
`132
`133
`134
`135
`136
`137
`138
`139
`140
`
`Famotidine
`Sumatriptan oral
`Promethazine/codeine
`Propranolol HCl
`Terazosin
`Polyethylene glycol
`Meclizine HCl
`Acyclovir
`Fentanyl transdermal
`Methotrexate
`Finasteride
`Ocella
`Ferrous sulfate
`Benzonatate
`Bupropion SR
`Methadone HCl non-inj
`Cheratussin AC
`Tizanidine HCl
`Quinapril
`Butalbital/APAP/caf
`Metoclopramide
`Clotrimazl/betamthsn
`Doxazosin
`Methocarbamol
`Budeprion XL
`Clobetasol
`Sprintec
`Nifedipine ER
`Aspirin, enteric-coated
`Fenofibrate
`Levetiracetam
`Nitroglycerin
`Chlorhexidine gluconate
`Baclofen
`Glipizide ER
`
`Total
`Rxs
`5,229,006
`5,223,235
`5,222,029
`5,220,771
`5,119,077
`5,058,545
`5,015,857
`4,965,632
`4,914,785
`4,824,399
`4,776,053
`4,745,699
`4,613,334
`4,613,236
`4,588,996
`4,558,532
`4,517,327
`4,456,271
`4,444,363
`4,421,620
`4,418,452
`4,395,864
`4,384,707
`4,312,914
`4,279,291
`4,135,641
`4,093,447
`4,072,226
`4,058,438
`4,024,628
`3,985,703
`3,954,867
`3,942,231
`3,926,533
`3,894,211
`
`% Change from
`previous year
`21.1%
`21.9%
`-8.2%
`-3.1%
`24.2%
`6.5%
`0.4%
`-11.1%
`4.1%
`2.2%
`14.7%
`-30.3%
`9.8%
`-2.7%
`33.4%
`4.2%
`-15.6%
`8.6%
`-12.5%
`1.8%
`-24.7%
`1.1%
`-19.8%
`10.3%
`-19.5%
`5.2%
`32.9%
`-6.9%
`10.0%
`66.6%
`34.5%
`4.5%
`5.7%
`10.5%
`-20.1%
`
`2 Drug topicS June 2011
`
`DrugTopics.com
`
`000002
`
`

`

`®
`
`Voice of the Pharmacist
`
`Source: SDI’s Vector One®: National
`2010 Top 200 generic drugs by total prescriptions
`
`Rank
`
`Drug
`
`141
`142
`143
`144
`145
`146
`147
`148
`149
`150
`151
`152
`153
`154
`155
`156
`157
`158
`159
`160
`161
`162
`163
`164
`165
`166
`167
`168
`169
`170
`
`Losartan pot/HCTZ
`Endocet
`Dicyclomine HCl
`Clarithromycin
`Bisoprolol/HCTZ
`Glyburide/metfrmn HCl
`Nabumetone
`Hydroxychloroquine
`Benztropine
`Ropinirole HCl
`Minocycline
`Trinessa
`Phenazopyridine HCl
`Phenytoin sodium ext
`Ketoconazole topical
`Hydroxyzine pamoate
`Prednisln sd phs oral
`Hydralazine
`Aviane
`Colchicine
`Nortriptyline
`Nystatin topical
`Bupropion ER
`Venlafaxine
`Oxybutynin chloride
`Atenolol chlorthalidone
`Labetalol
`Cefuroxime axetil
`Hydrocortisone top
`Morphine sulfate ER
`
`Total
`Rxs
`3,868,652
`3,839,086
`3,824,580
`3,699,625
`3,670,236
`3,642,002
`3,600,953
`3,499,968
`3,488,810
`3,482,989
`3,473,461
`3,439,792
`3,437,722
`3,397,018
`3,343,677
`3,339,856
`3,324,077
`3,310,180
`3,277,344
`3,258,225
`3,210,476
`3,182,575
`3,132,327
`2,980,525
`2,972,741
`2,958,298
`2,873,393
`2,848,451
`2,818,440
`2,740,358
`
`% Change from
`previous year
`NA
`-7.0%
`4.9%
`4.4%
`-5.6%
`-11.3%
`-3.5%
`1.7%
`12.5%
`-6.6%
`-8.0%
`-20.2%
`3.0%
`-2.3%
`-0.9%
`10.1%
`3.9%
`13.3%
`13.1%
`-3.2%
`3.5%
`10.7%
`29.3%
`15.8%
`3.7%
`-5.6%
`10.1%
`-6.8%
`2.4%
`15.6%
`
`Rank
`
`Drug
`
`171
`Fluocinonide
`172
`Clindamycin topical
`173
`Nystatin systemic
`174
`Prenatal 1+1
`175
`Tramadol HCl/APAP
`176
`Etodolac
`177
`Indomethacin
`178
`Diphenoxylate/atron
`179
`Phenobarbital
`180
`Oxcarbazepine
`181
`Diltiazem
`182
`Carbidopa/levodopa
`183
`Gianvi
`184
`Amiodarone
`185
`Felodipine ER
`186
`Cyanocobalamin
`187
`Oxybutynin chloride ER
`188
`Promethazine DM
`189
`Terbinafine HCl
`190
`Fexofenadine/pseudo
`191
`Ondansetron ODT
`192
`Hydromorphone HCl
`193
`Diltiazem SR
`194
`Ergocalciferol
`195
`Pramipexole dihydroc
`196
`Medroxyprogestrn tab
`197
`Carbamazepine
`198
`Benazepril/HCTZ
`199
`Prednisolone acet oph
`200
`Lithium carbonate
`Abbreviation: NA, not applicable.
`
`Total
`Rxs
`2,712,591
`2,712,155
`2,706,171
`2,640,573
`2,634,821
`2,626,654
`2,626,477
`2,605,506
`2,586,102
`2,558,268
`2,546,231
`2,504,723
`2,481,876
`2,481,428
`2,397,833
`2,355,482
`2,324,511
`2,310,171
`2,302,568
`2,299,824
`2,278,880
`2,272,481
`2,235,966
`2,229,337
`2,210,818
`2,204,729
`2,198,977
`2,190,722
`2,179,174
`2,136,800
`
`% Change from
`previous year
`-0.5%
`4.2%
`-2.1%
`-8.1%
`-4.4%
`0.4%
`7.1%
`11.3%
`-1.4%
`9.7%
`44.4%
`1.2%
`NA
`-3.1%
`-16.1%
`5.3%
`13.6%
`-8.7%
`0.0%
`857.3%
`19.7%
`14.3%
`16.7%
`>999
`NA
`-1.3%
`2.5%
`1.7%
`28.1%
`-6.0%
`
`3 Drug topicS June 2011
`
`DrugTopics.com
`
`000003
`
`