`US008168620B2
`
`c12) United States Patent
`Lulla et al.
`
`(10) Patent No.:
`(45) Date of Patent:
`
`US 8,168,620 B2
`May 1, 2012
`
`(54) COMBINATION OF AZELASTINE AND
`STEROIDS
`
`(75)
`
`Inventors: Amar Lu11a, Mumbai (IN); Geena
`Malhotra, Mumbai (IN)
`
`(73) Assignee: CIPLA Limited, Mumbai (IN)
`
`( *) Notice:
`
`Subject to any disclaimer, the term ofthis
`patent is extended or adjusted under 35
`U.S.C. 154(b) by 987 days.
`
`(21) Appl. No.:
`
`10/518,016
`
`(22) PCT Filed:
`
`Jun. 13, 2003
`
`(86) PCT No.:
`
`PCT /GB03/02557
`
`§ 371 (c)(l),
`(2), ( 4) Date:
`
`Jul. 6, 2005
`
`(87) PCT Pub. No.: W003/105856
`
`PCT Pub. Date: Dec. 24, 2003
`
`(65)
`
`Prior Publication Data
`
`US 2006/0025391 Al
`
`Feb.2,2006
`
`(30)
`
`Foreign Application Priority Data
`
`Jun. 14, 2002
`
`(GB) ................................... 0213739.6
`
`(51)
`
`Int. Cl.
`AOlN 45100
`(2006.01)
`A61K 31156
`(2006.01)
`A61K 31155
`(2006.01)
`A61K 31157
`(2006.01)
`A61K 31158
`(2006.01)
`A61K 9100
`(2006.01)
`A61P 37108
`(2006.01)
`A61P 27114
`(2006.01)
`A61P 11106
`(2006.01)
`(52) U.S. Cl. ....................................................... 514/171
`( 58) Field of Classification Search . ... ... ... ... .. ... . 514/171
`See application file for complete search history.
`
`(56)
`
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`
`Johann Richter
`Primary Examiner -
`Assistant Examiner - Thor Nielsen
`(74) Attorney, Agent, or Firm - Conley Rose, P.C.; Rodney
`B. Carroll
`
`ABSTRACT
`(57)
`A pharmaceutical product or formulation, which comprises
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`a pharmaceutically acceptable salt, solvate or physiologically
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`mulation being in a form suitable for nasal or ocular admin(cid:173)
`istration.
`Exhibit 1001
`IPR2017-00807
`ARGENTUM
`
`48 Claims, No Drawings
`
`000001
`
`
`
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