Medical
`Dictionary
`
`27th Edition
`
`Illustrated in Color
`
`Wiw WILKINS
`
`npry
`111unur NJi York
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`Syd iey
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`rig
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`ondon
`oky
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`Woter kiuwer
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`IiiIb
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`Ui
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`FAMY CARE - EXHIBIT 1022-0001
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`

`
`Senior vianaging Editor Maureen Barlow Pugh
`Managing Editor Barbara Werner
`Filardo MD
`iYew Terms Editor Thomas
`Francis Raymond Lukens Bonnie Montgomery
`Binns Linda
`Copy Editors Peter
`Chief On-Line Editor Barbara
`Ferretti
`On-Line Editors Kathryn Cadle Dana Workman
`Bollet MD Ted Burk Regina Layette
`Bloom MD Alfred
`Binns David
`Proofreaders Peter
`Dirckx MD Thomas
`Day Jr MD FCCP Richard Diamanti John
`Davis John
`Last MD FRACP FRCPC Raymond
`Filardo MD Linda
`Francis John
`Lukens Kate Mason CMT Joan Sarchese
`Database Programmers Dave Marcus Lexi-Comp Inc hudson OH
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`Hardy
`Illustrations Neil
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`
`2000 Lippincott Williams Wilkins
`Copyright
`351 West Camden Street
`Baltimore Maryland 212012436 USA
`
`by William Wood and Company 1911 1st ed 1912 2nd ed 1914 3rd ed 1916 4th ed
`Copyright
`1918 5th ed 1920 6th ed 1922 7th ed 1924 8th ed 1926 9th ed 1928 10th ed 1930 11th ed
`
`by Williams Wilkins 1933 12th ed 1935 13th ed 1939 14th ed 1942 15th ed 1946
`Copyright
`l6thed 1949 l7thed 1953 l8thed 1957 l9thed l96l2othed 19662lsted 197222nded
`1976 23rd ed 1982 24th ed 1990 25th ed 1995 26th ed
`
`All rights reserved This book is protected by copyright No part of this book may be reproduced in any
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`liability negligence or otherwise for any injury
`The publisher is not responsible as matter of product
`resulting from any material contained herein This publication contains information relating to general
`principles of medical care which should not be construed as specific instructions for individual patients
`inserts should be reviewed for current infonnation in-
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`Manufacturers product
`eluding contraindications dosages and precautions
`
`Database design by Lexi-Comp Inc Iludson OH
`Printed in the United States of America by World Color Inc
`
`Library of Congress Cataloging-in-Publication
`
`Data
`
`Stedman Thomas Lathrop 1853-1938
`Stedmans medical dictionamy 27th ed
`cm
`ISBN 0-683-40007-X regular
`Medicine Dictionaries
`
`iSBN 0-683-40008-8 deluxe
`Title Medical dictionary
`II Title
`13 S812m 1999
`Medicine Dictionary- English
`
`R12l
`.S8 1999
`610.3-dc2l
`
`99-056094
`
`000102030405
`12345
`
`FAMY CARE - EXHIBIT 1022-0002
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`

`
`keratitis
`
`actinic k., a reaction of the cornea to ultraviolet light.
`deep punctate k., sharply defined opacities in an otherwise clear
`cornea, occurring in syphilitic iritis.
`dendriform k., dendritic k., a form of herpetic k.
`diffuse deep k., SYN lr. profunda;
`Dimmer k., SYN lc. nurnrnularis.
`
`disciform k., large disk-shaped infiltration of the central or para-
`central corneal strorna. This lesion is deep and nonsuppurativc
`and is seen in virus infections, particularly herpetic. SYN k. disci-
`formis.
`
`k. discifor’mis, SYN disciforrn k.
`exposure k., inflammation of the cornea resulting from irritation
`caused by inability to close the eyelids. SYN lagophthalmic k.
`fascicular k., a phlyctenular k. followed by the formation of a
`band or fascicle of blood vessels extending from the margin
`toward the center.
`
`filamentary k., a condition characterized by the formation of
`epithelial filaments of varying size and length on the corneal
`surface. SYN k. filamentosa.
`
`k. filamento'sa, SYN filamentary K.
`geographic k., k. with coalescence of superficial lesions in herpes
`keratitis.
`
`herpetic k., inflammation of the cornea (or cornea and conjuncti-
`va) due to herpes simplex virus. SYN herpes corneae, herpetic
`keratoconjunctivitis.
`interstitial k., an inflammation of the corneal stroma, often with
`neovascularization.
`
`lagophthalmic k., SYN exposure k.
`k. linea’r-is mi’grans, a deep, linear corneal opacity stretching
`from limbus to limbus; associated with congenital syphilis.
`marginal k., a corneal inflammation at the limbus.
`
`metaherpetic k., a postinfcctious comeal inflammation in herpet-
`ic k. leading to epithelial erosion; not due to virus replication.
`mycotic k., an infection of the cornea of the eye caused by a
`fungus.
`necrotizing k., severe inflammation and destmction of corneal
`tissue that may be seen in response to herpes infection.
`neuroparalytic k., SYN neurotrophric l<;.
`neurotrophic k., inflammation of the cornea after corneal anes-
`thesia. SYN neuroparalytic k.
`k. nummula’ris, coin-shaped or round, discrete, grayish areas 0.5
`to 1.5 mm in diameter scattered throughout the various layers of
`the cornea. SYN Dimmer k.
`
`phlyctenular k., an inflammation of the corneal conjunctiva with
`the formation of small red nodules of lymphoid tissue (phlyctenu-
`lae) near the corneoscleral limbus. SYN scrofulous lc.
`pneumococcal/suppurative k., SYN serpiginous l<..
`polymorphic superficial k., epithelial degeneration occurring in
`starvation.
`
`k. profun’da, an inflammation of the posterior corneal stroma.
`SYN diffuse deep k.
`punctate k., k. puncta’ta, SYN keratic ;32*r*C':}f)ifzz!e.s‘, under p;+'ec‘ig;>i~
`rare.
`
`Sclerosing k., inflammation of the cornea complicating scleritis;
`characterized by opacitication of the corneal stroma.
`scrofulous k., SYN phlyctenular l<.
`serpiginous k., a severe, creeping, central, suppurative ulcer often
`due to pneurnococci. SYN pneumococcal/suppurative k., serpent
`ulcer of cornea.
`
`k. sic'ca, SYN lwrczrccozg2::2c‘tiriti.s\ sicca.
`Superficial linear kt, spontaneous, painful k. with epithelial ere»
`sion and folds in Bowman inernbrane.
`
`superficial punctate k., epithelial punctate k. associated with
`viral conjunctivitis. SYN Thygeson disease.
`tracliomatous k., SEE pannus, corneal pannus.
`vascular k., superficial cellular infiltration of the cornea and
`neovascularization between Bowman membrane and the epitheli-
`um.
`r
`
`vesicular k., k. with coalescence of areas of epithelial corneal
`edema.
`
`keratocys
`..,_....._.
`
`xerotic k., SYN l<;eratoznalaci2t.
`éfskerato-, kerat-. 1. The cornea. 2. Horny tissue or cells. SEE ALSO
`cerat-, cerato-.
`[G. keras, horn]
`filter-a-to-acran-tho~ma (ker’a-to—ak’an-tho’ma). A rapidly grow
`ing tumor that may be umbilicated, and usually occurs on exposed
`areas of the skin in elderly white men, which invades the dermis"
`but remains localized and usually resolves spontaneously if um‘
`treated; microscopically, the nodule is composed of well-differen
`tiated squamous epithelium with a central keratin mass that opens
`on the skin surface. [kerato- + G. akanrha, thorn, +-oma, tumor}
`ker-a-to~an-gi-orma (l<er'z”1-ti’)-an—jé-6'mz'1). SYN zuigiokeratoma
`ker-a-totcele (kcr’a-to-sel).
`Hernia of Descemet rnembran -
`through a defect in the outer layers of the cornea. [l<erato- + (3
`kélé, hernia]
`I
`ker-a-to-conjunc-ti-vi-tis (ker’a—t6-kon-jfingk'ti—vi’tiS).
`Intlam
`mation of the conjunctiva and of the cornea.
`"
`atopic k., a chronic papillary inflammation, of the conjunctit;
`showing Trantas dots in a patient with a history of atopy.
`epidemic k., follicular conjunctivitis followed by subepith
`corneal infiltrates; often caused by adenovirus type 8, less on
`monly by other types. SYN virus k.
`flash k., SYN ultraviolet la.
`herpetic k., SYN herpetic Z:ems.fz:‘.s-.
`microsporidian k., a form of k. often associated with irnrnu
`nosuppressed persons, such as those suffering from AIDS.
`k. sic’ca, k. associated with decreased tears. SEE ALSO Sjcrgre
`syndrome. SYN dry eye syndrome, keratitis sicca.
`superior limbic k., inflammatory edema of the superior Corrie
`scleral limbus.
`'
`
`olet irradiation. SYN actinic conjunctivitis, arc-flash conjunctivi
`flash k., ophthalmia nivalis, snow conjunctivitis, welder’S ct:
`junctivitis.
`- "'
`vernal k., SYN vernal «:*<>z;~;'2rr2c‘2‘z‘w‘z2‘.r.
`'
`virus k., SYN cpitlemic k.
`fiker-a«to-co-nus (ker’a—t6-k6’11us). A conical protrusion of
`cornea caused by thinning of the stroma; usually bilateral. SEE
`ALSO Fleischer ring, Munson sign. SYN conical cornea.
`[keratoe
`G. kcirzos, cone]
`keratoconus
`
`keratoconus
`
`circumscribed posterior k., congenital corneal defect characte
`ized by a craterlike defect on the posterior corneal surface.
`kerva-to-cri-coid (1{er"a-t<”)—l<ri’koyd). SYN ceratocriccid.
`ker-a-to-cyst (l<e,r’a—to
`t). Odontogenic cyst derived from F3?‘
`nants of the dental lamina and appearing as a unilocular or null
`locular radiolucency which may produce jaw expansion; epith I
`lining is characterized microscopically by a uniform tl1lClsillf3§5*_r_ i
`corrugated superficial layer of parakeratin, and a prominent E35
`layer composed of palisaded columnar cells; associated With.
`__§
`hifid rib basal cell nevus syndrome.
`odontogcnic k. (l<:e—ra't6-sist), a cyst of dental lamina origin 3*”
`a high recuirence rate and well-defined histologic criteria i?
`-_
`corrugated parakeratin surface, uniformly thin epithelium, 33‘;
`palisaded basal layer. One manifestation of the basal Cell tie‘-W5
`syndrome.
`
`FAMY CARE - EXHIBIT 1022-0003
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`

`
`palikinesia
`
`Palpatitl"
`
`ln~
`pal-i-ki-ne-sia, pal~i-ci-ne-sia (pa1—i-ki.-né’ze»a, —si—né’ze-:1).
`voluntary repetition of movements.
`[(3. palin, again, + kinésis,
`movement]
`
`pal-i-nal (pal’i-niil). Moving backward. [(3. palin, backward]
`palin-drome (pal’in-drom). In molecular biology, a self—comple—
`mentaiy nucleic acid sequence; a sequence identical to its comple—
`inentary strand, if both are “read” in the same 5’ to 3' direction, or
`inverted repeating sequences running in opposite directions (e.g.,
`S’—AGT—TGA—3') on either side of an axis of symmetry; p.’s
`occur at sites of important reactions (e.g., binding sites, sites
`cleaved by restriction enzymes); imperfect p.’s exist, as do inter»
`rupted p.’s that allow the formation of loops. [(3. palindramos, a
`running back]
`pal-in-dro-mia (pal-in—dro’mé—a). A relapse or recurrence of a
`disease. [G. paliltdromos, a running back, + -ia, condition]
`paI~in-drom-ic (pal-.in—d1,'om'i.k). Recurring.
`pali-sade (pal’i~sad).
`In pathology, a row of elongated nuclei
`parallel to each other. [Fr. palissade, fr. L. palus, a pale, stake]
`pal-la-di-uni (Pd) (pa-la’dé—1';1in). A metallic element resembling
`platinum, atomic no. 46, atomic wt. 106.42.
`[fr.
`the asteroid,
`Pallas; G. Pallas, goddess of wisdom]
`pall-an-es-the-sia ('pal’an—es-tliE'zE-ii). Absence of pallesthesia.
`SYN apallesthesia.
`[G. pallfi, to quiver, + nrzaisthésicz, iJ1sensibil—
`ity]
`pall~es~the~sia (pal’es-thé’zé—2‘i). The appreciation of vibration, a
`form of pressure sense; most acute when a vibrating tuning fork is
`applied over a bony prominence. SYN bone sensibility, pallesthetic
`sensibility, vibratory sensibility.
`[G. pallzi, to quiver, + aisthe’si.s',
`sensation]
`
`pall-es-tllet-ic (pal—es-thet’ik). Pertaining to pallesthesia.
`pal-li-al (pal’é—al). Relating to the pallium.
`palvliate (pa1’e-at). To reduce the severity of; to relieve slightly.
`SYN mitigate.
`[L. palliatns (adj), dressed in a pzzllium, cloaked]
`palli-a-tive (pal’e—a—tiv). Reducing the severity of; denoting the
`alleviation of symptoms without curing the underlying disease.
`palili-dal (pal'i—diil). Relating to the pallidum.
`pal-Ii-dec«t0~my (pal’i-dek’to-me). Excision. or destruction of the
`globus pallidus, usually by stereotaxy; a prefix may indicate the
`method used, e.g., chemopallidectoiny (destruction by a chemical
`agent), cryopallidectomy (destruction by cold). [pallidum + G.
`ektamé, excision]
`
`[L. pallidus,
`
`pal-li~do-a-mygdavlot-0-my (pal'i~d6—a—mig'df1—l0t'6—1né). Pro-
`duction of lesions in the globus pallidus and amygdaloid nuclei.
`[pallidum + ainygdala (1) + G. romé, a cutting]
`pal-li~d0-an-sot-0-my (pal'i-dd-an-sot’i')-me). Production of le~
`sions in the globus pallidus and ansa lenticularis.
`pal-li-dot-(rmy (pal—i—dot’()~m5). A destructive operation on the
`globus pallidus, done to relieve involuntary movements or muscu-
`lar rigidity. [pallidum + G. tomé, incision]
`pal~li~dum (pal’i.—d1”nin) [TA].
`SYN globux pallidus.
`pale]
`dorsal‘ p. [TA], those parts of the globus pallidus located gener-
`ally dorsal to the plane of the anterior cominissure; along with the
`dorsal striatum, functions in motor activities with cognitive ori-
`gins; also form part of the dorsal basal ganglia. SYN p. dorsale
`[TA].
`dorsal p.
`p. dorsale [TA],
`ventral p. [TA], those parts of the globus pallidus located ventral
`to the anterior commissure; includes portions of the substantia
`iunominata; along with the ventral stiiatum believed to function in
`motor activities with strong motivational or emotional contnicts_
`SYN p. ventralc [TA].
`p. ventrale [TA], SYN ventral p.
`pal~Ii-um (pal.’é~ilm) [TA]. SYN cerebral cortex.
`pal-lor (pa1’or). Paleness, as of the skin. [L.]
`cachectic p., SYN achromasia (1).
`palm (pahrn, pawlm) [TA]. The flat of the hand; the flexor or
`anterior surface of the hand, exclusive of the thumb and fingers;
`the opposite of the dorsum of the hand. SYN palma [TA].
`[L.
`palma]
`
`[L. cloak]
`
`liver 1)., exaggerated eiiythema of the thenar and hypothenar .e_-
`nences.
`
`[TA]. SYN palm,
`
`pal-ma, pl. palvmae (pawl’m2”1, pawl'rn€:)
`[Ll
`palm.
`p. ma’nus, palm of the hand.
`palmar (pawl’m2”ir) [TA]. Referring to the palm of the
`volar. SYN palmaris [TA].
`[L. palmaris, fr. palnza]
`[L.]
`pal-mar~is (pawl~1nz'tr’is) [TA]. SYN palinar, palniar.
`pal-mellin (pal’mel-in). A red coloring matter formed by an
`Palmella cmenta.
`
`‘
`
`$33
`
`Palmer, Walter L., US. physician, ’-"1896.
`peptic ulcer.
`
`P. acid In
`
`palm-ic (pal’mik). Beating; throbbing; relating to a palinu
`pal~n1i-tal-de-hyde (pal—mi-tal’dé-hid). Hexadecanal; the I
`bon aldehyde analog of palmitic acid; a constituent of plas
`gens.
`
`pal-mi-tate (pal’mi«t2"1t). A salt of palmitic acid.
`palmitic acid (pal—mit’ik). A common saturated fatty
`occurring in palm oil and olive oil as well as many other fa"
`waxes; the end product of mammalian fatty acid SyI‘ltll3...,_
`hexadecanoic acid.
`
`pal-mi-tin (pal'mi—tin). The triglyceride of palmitic acid
`'»
`ring in palm oil. SYN tripalmitin.
`9—Hexadecenoii: ea
`pal-mit-0vle~ic ac-id (pal’1ni—to—le’ik).
`monounsaturated l6—carbon acid; one of the common consti
`of the triacylglycerols of humanadipose tissue. SYN
`acid.
`
`'
`
`pal~mi~tyl al-co-hol (pa1’nii—ti1). syn Cetyl alcohol.
`pal~n10d-ic (pal—mod’il<). Relating to palmus (1).
`
`pal-11108-C0-py (pal-mos’k6—pe). Examination of the earth _,
`sation. [G. palmos, pulsation, + skopefi, to examine]
`pal-mus, pl. pal-mi (pal’m1"is, —mi). 1. SYN facial tic. 2. Rhy:
`fibrillary contractions in a muscle. sea ALSO jumping disc
`The heart beat. [G. palmas, pulsation, quivering]
`pal-pa-ble (pal’pa—b1).
`1. Perceptible to touch; capable in
`palpated. 2. Evident; plain. [see palpation]
`palpate (pal’p2'it). To examine by feeling and pressing WE
`palms of the hands and the fingers.
`
`fipalpa-tion (pal~p2'1’shfin). 1. Examination with the hands
`for organs, masses, or infiltration of a part of the body, fee I__.
`heart or pulse beat, vibrations in the chest, etc. 2. T0111}
`feeling, or perceiving by the sense of touch.
`[L. palpflff
`palpa, pp. —rztus, to touch, stroke]
`
`_‘
`
`palpation of liver
`
`bimanual 1)., use of both hands to feel organs or inasse
`cially in the abdomen or pelvis.
`light~toucl1 p., a method of determining the outlines of (trig,
`masses by lightly palpating the S111’filC€ with the tip of 3
`
`_
`
`FAMY CARE - EXHIBIT 1022-0004
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`

`
`relaxant
`
`1548
`
`reniform-
`
`()1: E,‘
`to resurface the tissue side.
`In dentistry,
`re-line (ré’lin’).
`SEE
`denture with new base material to make it fit more accurately,
`ALSO rebase.
`
`REM 1. Acronym for rapid eye movememir, under rmrvenzenr,->2,
`Acronym for reticular erythematous nz.ucin0sis. see REM 53.-,1-_
`drama.
`
`rem Abbreviation for mentgen-equivalent-man.
`Remak, Robert, Po1ish»German anatomist and histologist, l8l5~
`1865. SEE R. nuclear division, fibers, under fiber, ganglia, undar
`ganglion, plexus.
`’
`
`neurornuscular r., an agent, e.g., curare or succinylcholine, that
`produces relaxation of striated muscle by interruption of transmis-
`sion of nervous impulses at the myoneural junction.
`nondepolarizing r., an agent, e.g., tubocurarine,
`that paralyzes
`skeletal muscle without depolarization of the motor endplate, as
`in phase II block.
`
`smooth muscle r., an agent, such as an antispasmodic, bronchodi~
`lator, or vasodilator, that reduces the tension or tone of smooth
`(involuntary) muscle.
`lengthening, or
`1. Loosening,
`re-lax-a-lion (re-lak-sa’sln”1n).
`lessening of tension in a muscle. 2. In nuclear magnetic reso~
`nance, r. is the decay in magnetization of protons after the direc-
`tion of the surrounding magnetic field is changed; the different
`rates of r. for individual nuclei and tissues are used to provide
`contrast in imaging. [L. relaxatio (see relax)]
`cardioesophageal r., r. of the lower esophageal sphincter, which
`can allow reflux of acidic gastric contents into the lower esopha-
`gus, producing esophagitis.
`isometric r., decrease in tension of a muscle while the length
`remains constant because of fixation of the ends.
`isovolumetric r., SYNl,St)V’()ll1l11lC r‘.
`isovolumic r., that part of the cardiac cycle between the time of
`aortic valve closure and mitral opening, during which the ventric-
`ular muscle decreases its tension without lengthening so that
`ventricular volume remains unaltered; the heart is never precisely
`isovolumetric (vs. isovolumic) except during long diastoles with a
`midiastolic period of diastasis. SYN isovolumetric r.
`longitudinal r., in nuclear magnetic resonance, the return of the
`magnetic dipoles of the hydrogen nuclei (magnetization vector) to
`equilibrium parallel to the magnetic field, after they have been
`flipped 90°; varies in rate in different tissues, taking up to 15 s for
`water. SEE TI. SYN spin-lattice r., spin—spin r.
`spin-lattice r., SYN longitudinal 1;,
`spin-spin r., SYN longitudinal r.
`transverse r., in nuclear magnetic resonance, the decay of the
`nuclear magnetization vector at right angles to the magnetic field
`after the 90° pulse is turned off; the signal is called free induction
`decay. SEE T2; Cf. longitudinal r.
`re-lax-in (re-lak’sin). A polypeptide hormone secreted by the
`corpora lutea of mammalian species during pregnancy. Facilitates
`the birth process by causing a softening and lengthening of the
`pubic symphysis and cervix; it also inhibits contraction of the
`uterus and may play a role in timing of parturition. SYN cervilaxin,
`ovarian hormone, releasin.
`[relax + -in]
`re-learn-ing (ré—1err1’ing). The process of regaining a skill or
`ability that has been partially or entirely lost; savings involved in
`r., as compared with original learning, give an index of the degree
`of retention.
`
`re-leas-in.
`
`svw relaxin.
`
`re~li-a-bil~i~ty (ré—li-5-bil’i—tE). The degree of stability exhibited
`when a measurement is repeated under identical conditions. SEE
`correlation coeflicient, reliability coefficient.
`[M.E. relien,
`fr.
`O.Fr. relier, fr. L. religo, to bind]
`equivalent form r., in psychology, the consistency of measure-
`ment based on the correlation between scores on two similar
`forms of the same test taken by the same individual. SEE ALSO
`reliability coeficiezit.
`the consistency of measurement
`interjudge r., in psychology,
`obtained when different judges or examiners independently ad-
`minister the same test to the same individual. SYN interrater r.
`interrater r., SYN interjudge r.
`the consistency of measurement
`test-retest r.,
`in psychology,
`based on the correlation between test and retest scores for the
`same individual.
`ALSO coefficient, reliability.
`relief (re-lei’). 1. Removal of pain or distress, physical or mental.
`2. In dentistry, reduction or elimination of pressure from a specif-
`ic area under a denture base. sue ALSO relief arm, relief Chamber.
`[see relieve]
`
`re-lieve (re—lév’). To free wholly or partly from pain or discom~
`fort, either physical or mental. [through 0. Fr, fr. L. relevo, to lift
`up, lighten]
`
`[L.
`
`remediabilrfs,
`
`fr,-
`
`re-me-di-a-ble (rE—mé’dé~a—bl). Curable.
`remedio, to cure]
`re-me~di-al (ré—rné’clé—2”1l). Curative or acting as a remedy.
`rem-e-dy (rern’é—dé). An agent that cures disease or alleviatesi
`symptoms. (L. remedium, fr. re-, again, + medear, cure]
`.
`re-min-er~al~i~za~tion (ré’min’er-al-i—za’shfin).
`1. The return_
`the body or a local area of necessary mineral constituents 10
`through disease or dietary deficiencies; commonly used in re I
`ring to the content of calcium salts in bone. 2. In dentistry,
`process enhanced by the presence of fluoride whereby partial
`decalcified enamel, dentin, and cementum become recalcified h
`mineral replacement.
`In the psychology of learnin
`rem-i~nis-cence (rem-i—nis’sens).
`an improvement in recall, over that shown on the last trial,
`incompletely learned material after an interval without pract
`[L. remirziscentiae, from reminiscar, to remember]
`remission (ré—m,ish'fin). 1. Abatement or lessening in severity"
`the symptoms of a disease. 2. The period during which
`abatement occurs. [L. ren'zz'ssi(), fr. re-mitto, pp. -missus,
`to sea
`back, slacken, relax]
`'
`spontaneous r., disappearance of symptoms without formal tre
`ment.
`
`_
`
`re-mil: (ré—rnit’). To become less severe for a time without abso
`lutely ceasing. [see remission]
`"
`rermit-tence (re-rnit’ens). A temporary amelioration, without,
`tual cessation, of symptoms.
`re~mit<tent (ré—mit’ent). Characterized by temporary periods‘ t
`abatement of the symptoms of a disease.
`_
`rem-nant (rem’nant). Something remaining, a residue or vestig
`[O. Fr., fr. remaindre, to remain, fr. L. remaneo]
`’_
`re»mod-el-ing(re-mod’e1-ing). 1. A cyclic process by which boil
`maintains a dynamic steady state through sequential resorpli_0
`and formation of a small amount of bone at the same site; unlili
`the process of modeling, the size and shape of remodeled bop
`remain unchanged. 2. Any process of reshaping or reorganizrn
`
`(usually one or both ventricles) due to a pathologic or norm
`(neonatal) stimulus.
`
`ren, gen. reinis, pl. re-nes (ren, r'é’nis, re’néz). SYN kidney.
`re-nal (renal). SYN1‘1f3pl1I'lC
`
`[L3
`
`,
`tive configuration.
`ren-cu-1115 (l'C“’—k00‘1‘3S). 1. SYN cortical [obtains of kidney, ufliili.
`20121116. 2. SYN reniculus (2).
`Rendu, Henri J.L.M., French physician, 18444902.
`Osler-Weber syndroliie.
`zffireni-.
`reno-.
`
`SYN tsardiorenal.
`
`lftifli“
`
`renxi-cap-snle (ren’i—kap’sool). The capsule of the kidney. [f=?’“‘_
`+ L. capsular, capsule]
`renei-car-di-ac (ren’i-kar’dé—ak).
`kardia, heart]
`1. sm corti€3;l
`-11).
`(t~e~ni1<’u—1ns,
`renic-11-lus, pl. re-nic-u-li
`[clutter of kidney, under Ioiizaie.
`2. A lobe of the human mm.‘
`kidney and that of some lower animals in which fibrous 53?“;
`subdivide the organ. SYN renculus (2), renunculus (2).
`[L. din" of
`ren, kidney]
`ren«i-form (r‘en_’i_—f6m1). SYN nepliroitl.
`
`,
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`sickness
`
`Indian 5., sYN epidemic gangrenous proctitz'.r.
`Jamaican vomiting s., SYN ackee poisonin.g.
`milk s., a disease of humans caused by ingesting contaminated
`milk from cows suffering from trembles; clinical manifestations
`include severe vomiting, labored breathing, delirium, convulsions,
`coma, and death; recovery from nonlethal illness is slow. SYN
`lactimorbus.
`
`morning 5., the nausea and vomiting of early pregnancy. SYN
`morning vomiting, nausea gravidanun.
`motion s., the syndrome of pallor, nausea, weakness, and malaise,
`which may progress to vomiting and incapacitation, caused by
`stimulation of the semicircular canals during travel or motion as
`on a boat, plane, train, car, swing, or rotating amusement ride. SYN
`kinesia.
`
`mountain s., syn altitude s.
`radiation s., a systemic condition caused by substantial whole-
`body irradiation, seen after nuclear explosions or accidents, rarely
`after radiotherapy. Manifestations depend on dose, ranging from
`anorexia, nausea, vomiting, and mild leukopenia, to thrombocyto-
`penia with hemorrhage, severe leukopenia with infection, anemia,
`central nervous system damage, and death. SYN radiation poison-
`ing.
`sea s., motion s. occurring in boat travelers.
`serum s., an immune complex disease appearing some days (usu-
`ally 1—2 weeks) after injection of a foreign serum or serum pro-
`tein, with local and systemic reactions such as urticaria, fever,
`general lymphadenopathy, edema, arthritis, and occasionally albu-
`minuria or severe nephritis; originally described in patients re-
`ceiving serotherapy. The term is sometimes used for clinically
`similar allergic reactions to drugs. SYN serum disease, serum reac-
`tion.
`
`sleeping s., SEE Gambian trypaizosomiasis, Rhodesian tl’y])tlIl().S‘()-
`miasis.
`
`space s., dizziness as result of changes in inner ear resulting from
`absence of gravity. SYN physiologic vertigo.
`West African Sleeping 5., SYN Gambian itrypazlosomiasis.
`side (sid). One of the two lateral margins or surfaces of a body,
`midway between the front and back. [A.S. side]
`balancing s., in dentistry, the nonfunctioning s. from which the
`mandible moves during the working bite.
`working s., in dentistry, the lateral segment of a dentition toward
`which the mandible is moved during occlusal function.
`side effect. A result of drug or other therapy in addition to or in
`extension of the desired therapeutic effect; usually but not neces-
`sarily, connoting an undesirable effect. Although technically the
`therapeutic effect carried beyond the desired limit (e.g., a hemor-
`rhage from an anticoagulant) is a s. e., the term more often refers
`to pharmacologic results of therapy unrelated to the usual objec-
`tive (e.g., a development of signs of Cushing syndrome with
`steroid therapy).
`sid~er~a~tion (sid-er-a'sh1“in). Any sudden attack, as of apoplexy.
`[L. sideror, pp. sideratus, to be blasted or palsied by a constella-
`tion, fr. sidus (sider-), a constellation, the heavens]
`zffissidero-.
`Iron. [G. sidéros]
`Sid-e1‘~0*blaSt (sid’er—o—blast). An erytliroblast containing gran-
`ules of ferritin stained by the Prussian blue reaction. [sidero~ + G.
`blasms, germ]
`sid-er~o-cyte (sid'er-6-sit). An erythrocyte containing granules of
`free iron, as detected by the Prussian blue reaction, in the blood of
`normal fetuses, where they constitute from 0.l0~4.5% of the
`erythrocytes. [sidero— + G. kytos, cell]
`sid-er-o~fi~bro-sis (sid’er-6-fi—bro'sis). Fibrosis associated with
`small foci in which iron is deposited.
`sid~er-og-en-ous (sid—er~oj’e-nfis).
`Iron forming. [sidero- + (3.
`-gen, producing]
`sid-er-o-pe-nia (sid’er~o-pé’né»z"t). An abnormally low level of
`serum iron. [sidero- + G. perzia, poverty]
`sid-er-0-pe-nit: (sid'er-6-pé'nik). Cliaracterized by sideropenia.
`sid-er-aphage (sid’er-6—féj).
`sm sitlerophore.
`[sidero- + G.
`pllagé, to eat]
`sid-er-0-phil, sid~er-o-phile (sid’er~o~fi1, -til).
`
`1. Absorbing
`
`2. A cell or tissue that contains iron.
`
`iron. SYN siderophilous.
`[sidero» + G. philos, fond]
`Sid-er~oph-i-lins (sid»er—6~f1l’in, -of’i-lin). Nonheme, iron-b‘
`ing proteins; there are three central classes of _S.: transferrin (lj 0,‘,
`vertebrate blood), lactoferrin (in mammalian milk and other so
`tions), and conalbumin or ovotransferrin (avian blood and am
`egg white).
`
`afi-
`:-
`
`_
`sid-er-opli-i-lous (sid-er-of’i-lfis). SYN sid,erophil (1).
`sid-er-0-phore (sid'er-6-for). A large extravasated mononuclear
`phagocyte containing granules of hemosiderin, found in the sp'u-_‘
`turn or in the lungs of individuals with longstanding puluionary
`congestion from left ventricular failure. SEE ALSO heart failure eel
`SYN sideropliage.
`[sidero— + G. pharos, bearing]
`sidver-0-sil-i-co-sis (sid'er-5—sil'i-ké/sis). Silicosis due to inhal-
`tion of dust containing iron and silica. SYN silicosiderosi
`[side1'o- + silicosis]
`.
`>
`-
`Sid-er-0-sis (sid-er-o’sis). 1. A form of pneumoconiosis due to th
`presence of iron dust. 2. Discoloration of any part by disposjtizi
`of a pigment containing iron; usually called hemosiderosis. 3;"A'
`excess of iron in the circulating blood. 4. Degeneration of th
`retina, lens, and uvea as a result of the deposition of intraocul:
`iron. [sidero- + G. -osis, condition]
`-
`pulmonary s., SYN pnazm2oe0nio.ris siderotica.
`Sid-er-ot-ic (sid-er-ot’ik). Related to siderosis; pigmented by ‘lift:
`or containing an excess of iron.
`SIDS Acronym for sudden infant death syndrome.
`Siegert, Ferdinand, German pediatrician, 1865-1946. sen S. at
`Siegle, Emil, German otologist, 1833-1900. see S. otoscops-.5
`sie-mens (S) (se’1nenz). The SI unit of electrical conductance; tlt
`conductance of a body with an electrical resistance of l 5;:
`allowing 1 ampere of current to flow per volt applied; equal t
`mho. SYN rnho.
`[Sir William Siemens, Ger. born British engin
`1823-1883]
`
`3
`Siemerling, Ernst, German physician, 1857-1931.
`sieve (siv). A meshed or perforated device for separating :
`particles from coarser ones. [O.B. sive]
`»
`molecular s., a gel—1ike material with pore sizes of such ranges
`to exclude molecules above certain sizes; used in fractionating
`purifying macromolecules.
`'
`sievert (SV) (sé’vert). The S1 unit of ionizing radiation effct:
`dose, equal to the absorbed dose in gray, weighted for both:
`quality of radiation in question and the tissue response to ’:t
`radiation. The unit is the joule per kilogram and l Sv = 100.
`_.
`SEE effective dose, equivalent dose.
`SIF Abbreviation for somatotropin rclcase—inhibitit1gfactor.
`Sig. Abbreviation for L. signa, label, write, or signs
`__
`labeled.
`Siggaard—Andersen, Ole, Danish clinical biochemist. *‘19
`SEE Siggaard-Andersen nomogram.
`Sigh (si).
`1. An audible inspiration and expiration under».__th
`influence of some emotion. 2. To perform such an act.
`sfcarz]
`sight (sit). The ability or faculty of seeing.
`gesihth]
`day s., SYN nyctalopia.
`far 5., SYN hyperopia.
`long s., sYN hyperopia.
`near s., sYN myopia.
`night s., SYN hemeralopia.
`second 5., improved near vision in the aged as a result flf
`creased refra<:tiVi.ty of the nucleus of the lens causing III:/‘0i‘*3‘i
`senile lenticular myopia.
`short s., SYN myopia.
`sigrna (sig'ma). The 18th letter of the Greek alphabet, 6.
`sigrria-tism (sig'm2"l-tizm). SYN lisping,
`[G. sigma, £116 13:13
`sig-moid (sig'moyd). Resembling in outline the letter S or”?
`the forms of the Greek sigma.
`[(3. sigma,
`the letter S. 4*?‘
`resemblance]
`cffisigmoid-. SEE sigmoido-.
`
`ALSO vision.
`
`'
`[ii--3
`"
`
`,....
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`‘‘ theory
`
`therapy
`
`the impulses transmitted over the auditory nerve fibers corre-
`sponds to the frequency of the sound vibrations, and is the sole
`basis for pitch discrimination; a t. no longer tenable. SEE ALSO
`traveling wave 1:.
`thermodynamic t. of narcosis, that the interposition of narcotic
`molecules in nonaqueous cellular phase causes changes that inter-
`fere with facilitation of ionic exchange.
`traveling wave t., generally held» . that a wave travels from the
`base to the apex of the basilar membrane. of the cochlea in re-
`sponse to acoustic stimulation, and that the site of maximal dis-
`placement of the basilar membrane depends on the frequency of
`the stimulating tone with higher frequencies causing maximal
`displacement near the base and lower frequencies causing maxi-
`mal displacement near the apex.
`van’t Hoff t., that substances in dilute solution obey the gas laws.
`Cf. van’t Hoff law.
`
`Warburg t., that the development of cancer is due to irreversible
`damage to the respiratory mechanism of cells,
`leading to the
`selective multiplication of cells with increased glycolytic metabo-
`lism, both aerobic and anaerobic.
`Wollaston t., a t. that the semidecussation of the optic nerves at
`the chiasm is proved by the homonymous hemianopia seen in
`brain lesions.
`
`that there are three
`Young-Helmholtz t. offcolor vision, a t.
`color-perceiving elements in the retina: red, green, and blue. Per-
`ception of other colors arises from the combined stimulation of
`these elements; deficiency or absence of any one of these ele-
`ments results in inability to perceive that color and a mispercep-
`tion of any other color of which it forms a part. SYN Helmholtz t.
`of color vision.
`
`the-0~therra-py (the-6-th2‘1r’a-pé). Treatment of disease by prayer
`or religious exercises. [G. theos, god, + therapeia, therapy]
`théque (tek). A nest or aggregation of nevocytes in the epidermis.
`[Fr. 21 small box]
`
`ther-a-peu-sis (that-a-pf.i’sis). 1. SYN therapeutics. 2. SYN thera-
`PY-
`
`ther-a-peu-tic (that-5-pfi'tik). Relating to therapeutics or to the
`I treatment, remediating, or curing of a disorder or disease. {(3.
`thempeutikos]
`’
`ther-a-peu-tics (ther-E1-pfi'tiks_). The practical branch of medicine
`concerned with the treatment of disease or disorder. SYN therapeu-
`sis (1), therapia (2).
`[G. therapeutiké, medical practi