`
`Edwards Lifesciences v. Boston Scientific Scimed
` IPR2017-00060 U.S. Patent 8,992,608
` Exhibit 2056 - Part 2
` PROTECTIVE ORDER MATERIAL
`
`
`
`CoreValve ReValving
`
`Patients treated through July 4, 2008
`
`
`
`.
`
`with data collected through August 4, 2008
`
`
`
`: European enrollment complete, Canadian Sites to enroll additional patients
`
`C. C.1bil rig (Novvmbe' 2008)
`
`_
`.
`_
`_
`_
`_
`Edwards LIfeSCIences v. Boston Selentific Scimed
`
`Highly Confidential
`
`lPR2017-00060 u.s. Patent 8,992,608
`Exhibit 2056 - Part 2
`
`PROTECTIVE ORDER MATERIAL
`
`Page 22 0f “7
`
`EDWARDS 02079432
`
`
`
`CoreValve ReValving
`
`Patient Demographics
`
`
`
`
`
`C. Cam rug (Novvmbu' 2008)
`
`Highly Confidential
`
`Edwards Lifesciences v. Boston Scientific Scimed
`
`lPR2017-00060 u.s. Patent 8,992,608
`Exhibit 2056 - Part 2
`
`PROTECTIVE ORDER MATERIAL
`
`Page 23 0f “7
`
`EDWARDS 02079433
`
`
`
`Patient co-morbidities / history
`
`
`
`CoreValve ReValving
`
`C. Cabi‘ rig (Novvmbu' 2008)
`
`_
`_
`_
`_
`_
`_
`Edwards Lifesmences v. Boston Selentific Scumed
`
`Highly Confidential
`
`PROTECTIVE ORDER MATERIAL
`
`IPR2017-00060 u.s. Patent 8,992,608
`Exhibit 2056 - Part 2
`
`Page 24 0f “7
`
`EDWARDS 02079434
`
`
`
`CoreValve ReValving
`
`Procedural success
`
`
`
`
`
`C. Cilbii rig (Novvmbc’ 2008)
`
`Highly Confidential
`
`Edwards Lifesciences v. Boston Scientific Scimed
`
`lPR2017-00060 u.s. Patent 8,992,608
`Exhibit 2056 - Part 2
`
`PROTECTIVE ORDER MATERIAL
`
`Page 25 0f “7
`
`EDWARDS 02079435
`
`
`
`CoreValve ReValving
`
`Procedural complications*
`
`
`
`
`
`: Multiple events in same patients, data not cumulative
`
`C. C.1bil rig (Novvmbu' 2008)
`
`_
`.
`_
`_
`_
`_
`Edwards LIfeSCIences v. Boston Selentific Scimed
`
`Highly Confidential
`
`lPR2017-00060 u.s. Patent 8,992,608
`Exhibit 2056 - Part 2
`
`PROTECTIVE ORDER MATERIAL
`
`Page 25 0f “7
`
`EDWARDS 02079436
`
`
`
`CoreValve ReValving
`
`
`
`5 30-Day adverse events*
`
`C. Cabii rug (Novvmbu' 2008)
`
`_
`_
`_
`_
`_
`_
`Edwards Lifesmences v. Boston Scuentific Scumed
`
`Highly Confidential
`
`PROTECTIVE ORDER MATERIAL
`
`IPR2017-00060 u.s. Patent 8,992,608
`Exhibit 2056 - Part 2
`
`Page 27 0f “7
`
`EDWARDS 02079437
`
`
`
`CoreValve ReValving
`
`Paired comparative results at 30-Days
`
`
`
`
`
`C. Cabil rig (Novvmbu' 2008)
`
`Highly Confidential
`
`Edwards Lifesciences v. Boston Scientific Scimed
`
`IPR2017-00060 U.S. Patent 8,992,608
`Exhibit 2056 - Part 2
`
`PROTECTIVE ORDER MATERIAL
`
`Page 28 0f “7
`
`EDWARDS 02079438
`
`
`
`CoreValve ReValving
`
`Study Kaplan-IVIeier
`
`
`
`
`
`C. Cam rug (Novvmbu' 2008)
`
`Highly Confidential
`
`Edwards Lifesciences v. Boston Scientific Scimed
`
`lPR2017-00060 u.s. Patent 8,992,608
`Exhibit 2056 - Part 2
`
`PROTECTIVE ORDER MATERIAL
`
`Page 29 0f “7
`
`EDWARDS 02079439
`
`
`
`CoreValve ReValving
`
`Lessons learned
`
`
`
`
`
`C. Cam rug (Novvmbu' 2008)
`
`Highly Confidential
`
`Edwards Lifesciences v. Boston Scientific Scimed
`
`lPR2017-00060 u.s. Patent 8,992,608
`Exhibit 2056 - Part 2
`
`PROTECTIVE ORDER MATERIAL
`
`Page 3° 0‘ “7
`
`EDWARDS 02079440
`
`
`
`CoreValve ReValving
`
`Conclusions
`
`
`
`
`
`C. Cam rug (Novvmbu' 2008)
`
`Highly Confidential
`
`Edwards Lifesciences v. Boston Scientific Scimed
`
`lPR2017-00060 u.s. Patent 8,992,608
`Exhibit 2056 - Part 2
`
`PROTECTIVE ORDER MATERIAL
`
`Page 31 0f “7
`
`EDWARDS 02079441
`
`
`
`Page 32 of 117
`
`Edwards Lifesciences v. Boston Scientific Scimed
` IPR2017-00060 U.S. Patent 8,992,608
` Exhibit 2056 - Part 2
` PROTECTIVE ORDER MATERIAL
`
`
`
`Page 33 of 117
`
`Edwards Lifesciences v. Boston Scientific Scimed
` IPR2017-00060 U.S. Patent 8,992,608
` Exhibit 2056 - Part 2
` PROTECTIVE ORDER MATERIAL
`
`
`
`Page 34 of 117
`
`Edwards Lifesciences v. Boston Scientific Scimed
` IPR2017-00060 U.S. Patent 8,992,608
` Exhibit 2056 - Part 2
` PROTECTIVE ORDER MATERIAL
`
`
`
`CoreValve ReValvingTM
`
`
`
`Data as of Sept 2008
`
`Page 35 0f “7
`
`EDWARDS 02079445
`
`Clinical trials — underwa and
`
`C. C.ibil rig (Novwnbu' 2008)
`
`_
`_
`_
`_
`_
`_
`Edwards Lifesmences v. Boston Selentific Scumed
`
`Highly Confidential
`
`PROTECTIVE ORDER MATERIAL
`
`IPR2017-00060 u.s. Patent 8,992,608
`Exhibit 2056 - Part 2
`
`
`
`Direct Flow Medical
`
`Aortic Valve Prosthesis
`
`
`
`C. Cabii rug (Novvmbu' 2008)
`
`Highly Confidential
`
`Edwards Lifesciences v. Boston Scientific Scimed
`
`IPR2017-00060 U.S. Patent 8,992,608
`Exhibit 2056 - Part 2
`
`PROTECTIVE ORDER MATERIAL
`
`Page 35 0f “7
`
`EDWARDS 02079446
`
`
`
`Page 37 of 117
`
`Edwards Lifesciences v. Boston Scientific Scimed
` IPR2017-00060 U.S. Patent 8,992,608
` Exhibit 2056 - Part 2
` PROTECTIVE ORDER MATERIAL
`
`
`
`Direct Flow Medical
`
`Aortic Valve Prosthesis
`
`
`
`C. Cilbii rig (Novvmbc’ 2008)
`
`Highly Confidential
`
`Edwards Lifesciences v. Boston Scientific Scimed
`
`lPR2017-00060 u.s. Patent 8,992,608
`Exhibit 2056 - Part 2
`
`PROTECTIVE ORDER MATERIAL
`
`Page 33 0f “7
`
`EDWARDS 02079448
`
`
`
`Direct Flow Medical
`
`Aortic Valve Prosthesis
`
`
`
`C. Cam rig (NOVUIHbC' 2008)
`
`Highly Confidential
`
`Edwards Lifesciences v. Boston Scientific Scimed
`
`lPR2017-00060 u.s. Patent 8,992,608
`Exhibit 2056 - Part 2
`
`PROTECTIVE ORDER MATERIAL
`
`Page 39 0f “7
`
`EDWARDS 02079449
`
`
`
`Direct Flow Medical
`
`Aortic Valve Prosthesis
`
`
`
`C. Cabii rig (Novvmbu' 2008)
`
`Highly Confidential
`
`Edwards Lifesciences v. Boston Scientific Scimed
`
`lPR2017-00060 u.s. Patent 8,992,608
`Exhibit 2056 - Part 2
`
`PROTECTIVE ORDER MATERIAL
`
`Page 4° 0‘ “7
`
`EDWARDS 02079450
`
`