`
`If BAV Balloon Ruptures or Leaks
`During Deployment
`
`If Delivery System Balloon Ruptures
`or Leaks During Deployment
`
`
`
`Without THV Embolization
`Click Above to Play Video ‘
`
`Previous generation device used for illustration
`
`
`
`Page 137 of 172
`
`Edwards Lifesciences v. Boston Scientific Scimed
` IPR2017-00060 U.S. Patent 8,992,608
` Exhibit 2034 - Part 12
` PROTECTIVE ORDER MATERIAL
`
`
`
`l’/
`
`a: watfijerl
`
` %ill
`
`\l‘ C) UTCH lElCJDlJ".
`
`Differential Diagnosis
`Wide pulse pressure (with lower diastolic pressure than baseline) may
`indicate severe AR
`
`
`
`Management
`Depends on etiology
`
`Stabilization of hemodynamics priority
`
`Management can include post-dilatation or surgery
`
`
`
`Page 139 of 172
`
`Edwards Lifesciences v. Boston Scientific Scimed
` IPR2017-00060 U.S. Patent 8,992,608
` Exhibit 2034 - Part 12
` PROTECTIVE ORDER MATERIAL
`
`
`
`Page 140 of 172
`
`Edwards Lifesciences v. Boston Scientific Scimed
` IPR2017-00060 U.S. Patent 8,992,608
` Exhibit 2034 - Part 12
` PROTECTIVE ORDER MATERIAL
`
`
`
` t Click Above to Play Video ‘
`
`If regurgitation is central rather than paravalvular,
`post-dilate
`
`NOTE:
`
`
`
`Assessing Aortic Regurgitation:
`
`Central
`
`Management of Significant Central Aortic Regurgitation
`
`THV TOO
`
`VENTRICULAR
`
`(NON—FUNCTIONAL)
`
`
`
`Page 143 of 172
`
`Edwards Lifesciences v. Boston Scientific Scimed
` IPR2017-00060 U.S. Patent 8,992,608
` Exhibit 2034 - Part 12
` PROTECTIVE ORDER MATERIAL
`
`
`
`Page 144 of 172
`
`Edwards Lifesciences v. Boston Scientific Scimed
` IPR2017-00060 U.S. Patent 8,992,608
` Exhibit 2034 - Part 12
` PROTECTIVE ORDER MATERIAL
`
`
`
`Page 145 of 172
`
`Edwards Lifesciences v. Boston Scientific Scimed
` IPR2017-00060 U.S. Patent 8,992,608
` Exhibit 2034 - Part 12
` PROTECTIVE ORDER MATERIAL
`
`
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