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`FE13 2 8 1991
`. ,-.,I ..... $ .h'l, \ . .'!"riCE
`jQARD OF PATENT APPEALS
`AND INTERFERENCES
`
`•
`
`Paper No.
`
`14
`
`U.S. DEPARTMENT DF COMMERCE
`Patent and Trademark DHica
`
`Address: BOX INTERFERENCE
`Commissioner of Patents and Trademarks
`Washington, D.C. 20231
`
`•
`
`Telephone:
`Facsimile:
`
`(703)557-4007
`(703)557-8642
`
`Applicants: Cabilly et al
`Serial No.: 07/205,419
`Filed: June 10, 1988
`For: RECOMBINANT IMMUNOGLOBIN
`PREPARATIONS
`Accorded Benefit of: u.s.
`S.N. 06/483,457, filed
`04/08/83, now Patent No.
`4,816,567, issued 03/28/89
`
`The case referred to above has been forwarded to the
`
`Board of Patent Appeals and Interferences because it is adjudged
`
`to interfere with other cases hereafter specified. Attention is
`
`directed to the fact that this interference is declared pursuant
`
`to 37 CFR 1.601 et seq., effective February 11, 1985 (49 F.R.
`
`48416. 1050 O.G. 385). The interference is designated as No.
`
`102,572.
`
`By direction of the Commissioner of Patents and
`
`Trademarks and as required by 35 USC 135(c), notice is hereby
`
`given the parties of the requirement of the law for filing in the
`
`Patent and Trademark Office a copy of any agreement "in
`
`connection with or in contemplation of the termination of the
`
`interference."
`
`Sanofi/Regeneron Ex. 1 014, pg 438
`
`Merck Ex. 1014, pg 464
`
`
`
`r
`
`\
`
`.;.,_.
`
`•'
`
`./
`
`'
`
`•
`
`Serial No. 205,419
`
`-2-
`
`The cases involved in this interference are:
`
`Junior Party
`
`Patentees: Michael A. Boss, John H. Kenten, John S. Emtage
`and Clive R. Wood
`
`Address: 20 Hunter Court, Huntercombe Lane North, Slough,
`Berkshire, SL1 6DS, U.K.
`24 Avery Avenue, Downley, High Wycombe, Buckinghamshire,
`U.K.
`12 Benjamin House, Arnersham Hill, High Wycombe,
`Buckinghamshire, U.K.
`'Whych Wood', Buddle Hill, North Gorley, Near
`Fordingbridge, Hampshire, U.K.
`
`Serial No.: 06/672,265, filed 11/14/84, now Patent No. 4,816,397,
`issued 03/28/89
`
`For: MULTICHAIN POLYPEPTIDES OR PROTEINS AND PROCESSES FOR THEIR
`PRODUCTION
`
`Assignee: Celltech Limited, Berkshire SL1 4DY, U.K., A British
`Company
`
`Attorneys of Record: Paul N. Kokulis, Allen Kirkpatrick,
`Lloyd J. Street, George T. Mobille, James L. Dooley,
`Alvin Guttag, Raymond F. Lippitt, G. Lloyd Knight,
`Carl G. Love, Lawrence A. Hyrne, Akin T. Davis,
`Edgar H. Martin, William K. West, Jr., Kevin E.
`Joyce, Edward M. Prince, Donald B. Deaver, David w.
`Brinkman, George M. Sirilla, William T. Bullinger,
`Donald J. Bird, Larry s. Nixon, James R. Longacre,
`Arthur R. Crawford, W. Warren Taltavull, Michael L.
`Keller, Charles R. Donohoe, Sherman 0. Parrett,
`Robert A. Vanderhye, Watson T. Scott, Peter W.
`Gowdey, Michael A. Lechter, Dale S. Lazar, James T.
`Hosmer and Glenn J. Perry
`
`Associate Attorney: None
`
`Accorded Benefit of: None
`
`Address: Cushman, Darby & Cushman
`Eleventh Floor
`1615 L Street, N.W.
`Washington, DC 20036
`
`Sanofi/Regeneron Ex. 1 014, pg 439
`
`Merck Ex. 1014, pg 465
`
`
`
`r
`
`Serial No. 205,419
`
`-3-
`
`Senior Party
`
`Applicants: Shmuel Cabilly, Herbert L. Heyneker,
`William E. Holmes, Arthur D. Riggs and
`Ronald B. Wetzel
`Address: 2038 s. Peck, Monrovia, CA 91016
`2621 Easton Drive, Burlingame, CA 94010
`29 Eastlake, Pacifica, CA 94044
`4852 St. Andres Avenue, La Verne, CA 91750
`76 Melrose Avenue, San Francisco, CA 94131
`
`Serial No.: 07/205,419, filed 06/10/88
`
`For: RECOMBINANT IMMUNOGLOBULIN PREPARATIONS
`
`Assignee: Genentech, Inc., South San Franciscq, CA, A California
`Corporation
`
`Attorneys of Record: Walter H. Dreger, Thomas D. Kiley,
`Kate H. Murashige, Max D. Hensley and Janet E. Hasak
`
`Associate Attorneys: None
`Accorded Benefit of: u.s. S.N. 06/483,457, filed 04/08/83, now
`Patent No. 4,816,567, issued 03/28/89
`
`Address: Max D. Hensley
`Genentech, Inc.
`460 Point San Bruno Blvd.
`So. San Francisco, CA 94080
`
`I
`I
`
`Sanofi/Regeneron Ex. 1 014, pg 440
`
`Merck Ex. 1014, pg 466
`
`
`
`.·, ...
`
`•
`
`Serial No. 205,419
`
`count 1
`
`-4-
`
`A process for producing an Ig molecule or an
`immunologically functional Ig fragment comprising at least the
`variable domains of the Ig heavy and light chains, in a single
`host cell, comprising the steps of:
`
`transforming said single host cell with a first
`(i)
`DNA sequence encoding at least the variable domain of the Ig
`heavy chain and a second DNA sequence encoding at least the
`variable domain of the Ig light chain, and
`
`independently expressing said first DNA
`(ii)
`sequence and said second DNA sequence so that said Ig heavy and
`light chains are produced as separate molecules in said
`transformed single host cell.
`
`The claims of the parties which correspond to this
`
`count are:
`
`Boss et al: Claims 1-18.
`
`Cabilly et al: Claims 101-120.
`
`MFD/raj
`
`. Downey
`er-in-Chief
`557-4003
`
`Sanofi/Regeneron Ex. 1 014, pg 441
`
`Merck Ex. 1014, pg 467
`
`
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