Cancer of the Breast - SEER Stat Fact Sheets
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`Surveillance,Epidem iology,and End Results Program
`Turning Cancer Data Into Discovery
`
`Hom e
`Statistical Sum m aries
`Cancer Stat Fact Sheets
`SEER Stat Fact Sheets:Breast Cancer
`
`Cancer of the Breast
`
`Statistics at a Glance
`At a Glance
`Estim ated New
`Cases in 2015
`% of All New Cancer
`Cases
`
`231,840
`
`14.0%
`
`Estim ated Deaths
`in 2015
`% of All
`Cancer Deaths
`
`40,290
`
`6.8%
`
`Percent Surviving
`5 Years
`
`89.4%
`
`2005-2011
`
`Num ber of New Cases and Deaths per 100,000:The num ber of new cases of breast cancer was 124.8 per 100,000 wom en per year.The num ber of deaths was 21.9 per 100,000 wom en per year.These rates
`are age-adjusted and based on 2008-2012 cases and deaths.
`
`Lifetim e Risk of Developing Cancer:Approxim ately 12.3 percent of wom en will be diagnosed with breast cancer at som e point during their lifetim e,based on 2010-2012 data.
`
`Prevalence of This Cancer:In 2012,there were an estim ated 2,975,314 wom en living with breast cancer in the United States.
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`http://seer.cancer.gov/statfacts/html/breast.html
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`9/8/2015
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`PETITIONER'S EXHIBITS
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`Exhibit 1039 Page 1 of 8
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`Cancer of the Breast - SEER Stat Fact Sheets
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`Page 2 of 8
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`Survival Statistics
`How Many People Survive 5 Years Or More after Being Diagnosed with Breast Cancer?
`Relative survival (http://surveillance.cancer.gov/survival/m easures.htm l) statistics com pare the survival of patients diagnosed with cancer with the survival of people in the general population who are the sam e age,
`race,and sex and who have not been diagnosed with cancer.Because survival statistics are based on large groups of people,they cannot be used to predict exactly what will happen to an individual patient.
`No two patients are entirely alike,and treatm ent and responses to treatm ent can vary greatly.
`
`Percent Surviving
`5 Years
`
`89.4%
`
`Based on data from SEER 18 2005-2011.Gray figures represent those who have died from breast cancer.Green figures represent those who have survived 5 years or m ore.
`
`Additional Inform ation
`
`More about 5-year survival rates (http://seer.cancer.gov/statistics/types/survival.htm l)
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`http://seer.cancer.gov/statfacts/html/breast.html
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`9/8/2015
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`PETITIONER'S EXHIBITS
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`Exhibit 1039 Page 2 of 8
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`Cancer of the Breast - SEER Stat Fact Sheets
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`Survival by Stage
`Cancer stage at diagnosis,which refers to extent of a cancer in the body,determ ines treatm ent options and has a strong influence on the length of survival.In general,if the cancer is found only in the part of
`the body where it started it is localized(som etim es referred to as stage 1).If it has spread to a different part of the body,the stage is regionalor distant.The earlier breast cancer is caught,the better chance
`a person has of surviving five years after being diagnosed.For breast cancer,61.1% are diagnosed at the local stage.The 5-year survival for localized breast cancer is 98.6%.
`
`Percent of Cases & 5-Year Relative Survival by Stage at Diagnosis:Breast Cancer
`Percent of Cases by Stage
`5-Year Relative Survival
`
`Localized (61%)
`Confined to
`Prim ary Site
`Regional (32%)
`Spread to Regional
`Lym ph Nodes
`Distant (6%)
`Cancer Has
`Metastasized
`Unknown (2%)
`Unstaged
`
`SEER 18 2005-2011,All Races,Fem ales by SEER Sum m ary Stage 2000
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`Additional Inform ation
`
`More about breast cancer staging (http://www.cancer.gov/cancertopics/pdq/treatm ent/breast/Patient/page2)
`
`http://seer.cancer.gov/statfacts/html/breast.html
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`9/8/2015
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`PETITIONER'S EXHIBITS
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`Exhibit 1039 Page 3 of 8
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`Cancer of the Breast - SEER Stat Fact Sheets
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`Num ber of New Cases and Deaths
`How Com m on Is This Cancer?
`Com pared to other cancers,breast cancer is fairly com m on.
`
`Com m on Types of Cancer
`1. Breast Cancer (Fem ale)
`2. Lung and Bronchus Cancer
`3. Prostate Cancer
`4. Colon and Rectum Cancer
`5. Bladder Cancer
`6. Melanom a of the Skin
`7. Non-Hodgkin Lym phom a
`8. Thyroid Cancer
`9. Kidney and Renal Pelvis Cancer
`10. Endom etrial Cancer
`
`Estim ated New
`Cases 2015
`231,840
`221,200
`220,800
`132,700
`74,000
`73,870
`71,850
`62,450
`61,560
`54,870
`
`Estim ated
`Deaths 2015
`40,290
`158,040
`27,540
`49,700
`16,000
`9,940
`19,790
`1,950
`14,080
`10,170
`
`Breast cancer represents 14.0% of all new cancer
`cases in the U.S.
`
`14.0%
`
`In 2015,it is estim ated that there will be 231,840 new cases of breast cancer and an estim ated 40,290 people will die of this disease.
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`http://seer.cancer.gov/statfacts/html/breast.html
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`9/8/2015
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`PETITIONER'S EXHIBITS
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`Exhibit 1039 Page 4 of 8
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`

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`Cancer of the Breast - SEER Stat Fact Sheets
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`Page 5 of 8
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`Who Gets This Cancer?
`Fem ale breast cancer is m ost com m on in m iddle-aged and older wom en.Although rare,m en can develop breast cancer as well.The num ber of new cases of breast cancer was 124.8 per 100,000 wom en per
`year based on 2008-2012 cases.
`
`Percent of New Cases by Age Group:Breast Cancer
`
`Breast cancer is m ost
`frequently diagnosed
`am ong wom en aged 55-
`64.
`
`Median Age
`At Diagnosis
`
`61
`
`SEER 18 2008-2012,All Races,Fem ales
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`Num ber of New Cases per 100,000 Persons by Race/Ethnicity:Breast Cancer
`
`Sex-SpecificCancer
`
`All Races
`
`White
`
`Black
`
`Asian /
`Pacific Islander
`Am erican Indian /
`Alaska Native
`
`Hispanic
`
`Non-Hispanic
`
`SEER 18 2008-2012,Age-Adjusted
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`http://seer.cancer.gov/statfacts/html/breast.html
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`9/8/2015
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`PETITIONER'S EXHIBITS
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`Exhibit 1039 Page 5 of 8
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`Cancer of the Breast -SEER Stat Fact Sheets
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`Who Dies From This Cancer?
`Overall,female breast cancer survival is good. However,women who are diagnosed at an advanced age may be more likely than younger women to die of the disease. Breast cancer is the fourth leading cause
`of cancer death in the United States. The number of deaths was 21.9 per 100,000 women per year based on 2008-2012.
`
`Percent of Deaths by Age Group: Breast Cancer
`
`The percent of breast
`cancer deaths is highest
`among women aged 55-
`64.
`
`Median Age
`At Death
`
`68
`
`U.S. 2008-2012,All Races,Females
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`Number of Deaths per 100,000 Persons by Race/Ethnicity: Breast Cancer
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`Sex-SpecificCancer
`
`All Races
`
`White
`
`Black
`
`Asian /
`Pacific Islander
`American Indian /
`Alaska Native
`
`Hispanic
`
`Non-Hispanic
`
`U.S. 2008-2012,Age-Adjusted
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`http://seer.cancer.gov/statfacts/html/breast.html
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`9/8/2015
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`PETITIONER'S EXHIBITS
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`Exhibit 1039 Page 6 of 8
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`

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`Cancer of the Breast -SEER Stat Fact Sheets
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`Trends in Rates
`Changes Over Time
`Keeping trackof the number of new cases,deaths,and survival over time (trends)can help scientists understand whether progress is being made and where additional research is needed to address
`challenges,such as improving screening or finding better treatments.
`
`Using statistical models for analysis,rates for new breast cancer cases have been stable over the last 10 years. Death rates have not changed significantly over 2002-2012. 5-year survival trends are shown
`below the figure.
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`New Cases,Deaths and 5-Year Relative Survival
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`View Data Table (http://seer.cancer.govld/breast.html)
`
`1985
`1980
`1975
`Year
`78.4%
`74.8%
`75.2%
`5-Year Relative Survival
`SEER 9 Incidence & U.S. Mortality 1975-2012,All Races,Females. Rates are Age-Adjusted.
`
`1990
`84.6%
`
`1995
`86.8%
`
`1999
`89.6%
`
`2003
`89.7%
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`2007
`91.0%
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`http://seer.cancer.gov/statfacts/html/breast.html
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`9/8/2015
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`PETITIONER'S EXHIBITS
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`Exhibit 1039 Page 7 of 8
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`

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`Cancer of the Breast -SEER Stat Fact Sheets
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`More About This Cancer
`Cancer and the Female Breast
`
`(http://seer.cancer.gov/i/factsheets/breast-lg.jpg)
`Figure: Breast and Adjacent Lymph Nodes
`Inside a woman's breast are 15 to 20 sections,or lobes. Each lobe is made of many smaller sections called lobules. Fibrous tissue and fat fill the spaces between the lobules and ducts (thin tubes that connect
`the lobes and nipples). Breast cancer occurs when cells in the breast grow out of control and form a growth or tumor. Tumors may be cancerous (malignant)or not cancerous (benign).
`
`Additional Information
`
`Learn more about female breast cancer (http://www.cancer.gov/cancertopics/types/breast)
`More Information
`Here are some resources for learning more about female breast cancer.
`
`About risk factors for breast cancer (http://www.cancer.gov/cancertopics/pdq/treatment/breast/Patient#Keypoint2)
`About breast cancer screening (http://cancer.gov/cancertopics/pdq/screening/breast/Patient/page1)
`About symptoms and diagnosis of breast cancer (http://www.cancer.gov/cancertopics/pdq/treatment/breast/Patient#Keypoint4)
`About treatment options for breast cancer (http://cancer.gov/cancertopics/pdq/treatment/breast/Patient/page5)
`About clinical trials (http://www.cancer.gov/clinicaltrials)
`About breast cancer prevention (http://cancer.gov/cancertopics/pdq/prevention/breast/Patient/page3)
`About cancer prevention (http://www.cancer.gov/cancertopics/pdq/prevention/overview/patient)
`References
`All statistics in this report are based on statistics from SEER and the Centers for Disease Control and Prevention's National Center for Health Statistics. Most can be found within:
`
`Howlader N,Noone AM,Krapcho M,Garshell J,Miller D,Altekruse SF,Kosary CL,Yu M,Ruhl J,Tatalovich Z,Mariotto A,Lewis DR,Chen HS,Feuer EJ,Cronin KA (eds). SEER Cancer Statistics Review,1975-
`2012,National Cancer Institute. Bethesda,MD,http://seer.cancer.gov/csr/1975_2012/ (http://seer.cancer.gov/csr/),based on November 2014 SEER data submission,posted to the SEER web site,April 2015.
`Suggested Citation
`All material in this report is in the public domain and may be reproduced or copied without permission;citation as to source,however,is appreciated.
`
`SEER Cancer Statistics Factsheets: Breast Cancer. National Cancer Institute. Bethesda,MD,http://seer.cancer.gov/statfacts/html/breast.html (http://seer.cancer.gov/statfacts/html/breast.html)
`
`ThisfactsheetfocusesonpopulationstatisticsthatarebasedontheUSpopulation.Becausethesestatisticsarebasedonlargegroupsofpeople,theycannotbeusedtopredictexactlywhatwillhappentoan
`individualpatient.Toseetailoredstatistics,browsetheSEERCancerStatisticsReview(http://seer.cancer.gov/csr/).Toseestatisticsforaspecificstate,gototheStateCancerProfiles(http://statecancerprofiles.cancer.gov/).
`
`Thestatisticspresentedinthisfactsheetarebasedonthemostrecentdataavailable,mostofwhichcanbefoundintheSEERCancerStatisticsReview(http://seer.cancer.gov/csr/).Insomecases,differentyearspans
`maybeused.Estimatesforthecurrentyeararebasedonpastdata.
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`Cancerisacomplextopic.Thereisawiderangeofinformationavailable.Thisfactsheetdoesnotaddresscauses,symptoms,diagnosis,treatment,follow-upcare,ordecisionmaking,althoughitprovideslinksto
`informationinmanyoftheseareas.
`
`The SEER Website is a service of the Surveillance Research Program,in NCI's Division of Cancer Control and Population Sciences
`
`NIH... Turning Discovery Into Health
`®
`
`http://seer.cancer.gov/statfacts/html/breast.html
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`9/8/2015
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`PETITIONER'S EXHIBITS
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`Exhibit 1039 Page 8 of 8