`
`Cancer of the Prostate SEER Stat Fact Sheets
`
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` Statistical Summaries
` Cancer Stat Fact Sheets
`SEER Stat Fact Sheets: Prostate Cancer
`
` Cancer of the Prostate
`
`Statistics at a Glance
`At a Glance
`
`Estimated New
`Cases in 2016
`% of All New Cancer
`Cases
`
`180,890
`
`10.7%
`
`Estimated Deaths
`in 2016
`% of All
`Cancer Deaths
`
`26,120
`
`4.4%
`
`Percent Surviving
`5 Years
`
`98.9%
`
`2006-2012
`
`Number of New Cases and Deaths per 100,000: The number of new cases of prostate cancer was 129.4 per 100,000 men per year. The number of deaths was
`20.7 per 100,000 men per year. These rates are age-adjusted and based on 2009-2013 cases and deaths.
`
`Lifetime Risk of Developing Cancer: Approximately 12.9 percent of men will be diagnosed with prostate cancer at some point during their lifetime, based on
`2011-2013 data.
`
`Prevalence of This Cancer: In 2013, there were an estimated 2,850,139 men living with prostate cancer in the United States.
`
`Survival Statistics
`
`JANSSEN EXHIBIT 2089
`Wockhardt v. Janssen IPR2016-01582
`
`
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`10/3/2016
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`Survival Statistics
`How Many People Survive 5 Years Or More after Being Diagnosed with Prostate Cancer?
`Relative survival (http://surveillance.cancer.gov/survival/measures.html) statistics compare the survival of patients diagnosed with cancer with the survival of people in
`the general population who are the same age, race, and sex and who have not been diagnosed with cancer. Because survival statistics are based on large groups of
`people, they cannot be used to predict exactly what will happen to an individual patient. No two patients are entirely alike, and treatment and responses to
`treatment can vary greatly.
`
`Cancer of the Prostate SEER Stat Fact Sheets
`
`Percent Surviving
`5 Years
`
`98.9%
`
`Based on data from SEER 18 2006-2012. Gray figures represent those who have died from prostate cancer. Green figures represent those who have survived 5 years
`or more.
`
`Additional Information
`
`More about 5-year survival rates (http://seer.cancer.gov/statistics/types/survival.html)
`
`Survival by Stage
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`10/3/2016
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`Survival by Stage
`Cancer stage at diagnosis, which refers to extent of a cancer in the body, determines treatment options and has a strong influence on the length of survival. In
`general, if the cancer is found only in the part of the body where it started it is localized (sometimes referred to as stage 1). If it has spread to a different part of
`the body, the stage is regional or distant. The earlier prostate cancer is caught, the better chance a person has of surviving five years after being diagnosed. For
`prostate cancer, 80.0% are diagnosed at the local stage. The 5-year survival for localized prostate cancer is 100.0%.
`
`Cancer of the Prostate SEER Stat Fact Sheets
`
`Percent of Cases & 5-Year Relative Survival by Stage at Diagnosis: Prostate Cancer
`Percent of Cases by Stage
`5-Year Relative Survival
`
`Localized (80%)
`Confined to
`Primary Site
`Regional (12%)
`Spread to Regional
`Lymph Nodes
`Distant (4%)
`Cancer Has
`Metastasized
`Unknown (4%)
`Unstaged
`
`SEER 18 2006-2012, All Races, Males by SEER Summary Stage 2000
`
`Additional Information
`
`More about prostate cancer staging (http://www.cancer.gov/types/prostate/patient/prostate-treatment-pdq#section/all)
`
`Number of New Cases and Deaths
`
`
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`10/3/2016
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`Number of New Cases and Deaths
`How Common Is This Cancer?
`Compared to other cancers, prostate cancer is fairly common.
`
`Cancer of the Prostate SEER Stat Fact Sheets
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`Common Types of Cancer
`1. Breast Cancer (Female)
`2. Lung and Bronchus Cancer
`3. Prostate Cancer
`4. Colon and Rectum Cancer
`5. Bladder Cancer
`6. Melanoma of the Skin
`7. Non-Hodgkin Lymphoma
`8. Thyroid Cancer
`9. Kidney and Renal Pelvis Cancer
`10. Leukemia
`
`Estimated New
`Cases 2016
`246,660
`224,390
`180,890
`134,490
`76,960
`76,380
`72,580
`64,300
`62,700
`60,140
`
`Estimated
`Deaths 2016
`40,450
`158,080
`26,120
`49,190
`16,390
`10,130
`20,150
`1,980
`14,240
`24,400
`
`Prostate cancer represents 10.7% of all
`new cancer cases in the U.S.
`
`10.7%
`
`In 2016, it is estimated that there will be 180,890 new cases of prostate cancer and an estimated 26,120 people will die of this disease.
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`Who Gets This Cancer?
`
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`10/3/2016
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`Who Gets This Cancer?
`Prostate cancer occurs only in men, and it is more common in older men than younger men. It is more likely to occur in men with a family history of prostate
`cancer and men of African American descent. The number of new cases of prostate cancer was 129.4 per 100,000 men per year based on 2009-2013 cases.
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`Cancer of the Prostate SEER Stat Fact Sheets
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`Percent of New Cases by Age Group: Prostate Cancer
`
`Prostate cancer is most
`frequently diagnosed
`among men aged 65-74.
`
`Median Age
`At Diagnosis
`
`66
`
`SEER 18 2009-2013, All Races, Males
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`
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`10/3/2016
`Cancer of the Prostate SEER Stat Fact Sheets
`Number of New Cases per 100,000 Persons by Race/Ethnicity: Prostate Cancer
`
`Sex-Specific Cancer
`
`All Races
`
`White
`
`Black
`
`Asian /
`Pacific Islander
`American Indian /
`Alaska Native
`
`Hispanic
`
`Non-Hispanic
`
`SEER 18 2009-2013, Age-Adjusted
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`Who Dies From This Cancer?
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`10/3/2016
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`Who Dies From This Cancer?
`Because we have screening for prostate cancer, most of the time it is caught before it spreads to other parts of the body. Men who have prostate cancer that is
`characterized as localized or regional are not as likely to die as men whose cancer is distant. In general prostate cancer has excellent survival rates, but death rates
`are higher in African American men, men who have advanced stage cancer, and men who are between the ages of 75 and 84. Prostate cancer is the sixth leading
`cause of cancer death in the United States. The number of deaths was 20.7 per 100,000 men per year based on 2009-2013.
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`Cancer of the Prostate SEER Stat Fact Sheets
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`Percent of Deaths by Age Group: Prostate Cancer
`
`The percent of prostate
`cancer deaths is highest
`among men aged 75-84.
`
`Median Age
`At Death
`
`80
`
`U.S. 2009-2013, All Races, Males
`
`
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`10/3/2016
`Cancer of the Prostate SEER Stat Fact Sheets
`Number of Deaths per 100,000 Persons by Race/Ethnicity: Prostate Cancer
`
`Sex-Specific Cancer
`
`All Races
`
`White
`
`Black
`
`Asian /
`Pacific Islander
`American Indian /
`Alaska Native
`
`Hispanic
`
`Non-Hispanic
`
`U.S. 2009-2013, Age-Adjusted
`
`Trends in Rates
`
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`10/3/2016
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`Trends in Rates
`Changes Over Time
`Keeping track of the number of new cases, deaths, and survival over time (trends) can help scientists understand whether progress is being made and where
`additional research is needed to address challenges, such as improving screening or finding better treatments.
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`Cancer of the Prostate SEER Stat Fact Sheets
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`Using statistical models for analysis, rates for new prostate cancer cases have been falling on average 5.1% each year over the last 10 years. Death rates have been
`falling on average 3.5% each year over 2004-2013. 5-year survival trends are shown below the figure.
`
`New Cases, Deaths and 5-Year Relative Survival
`
`View Data Table (http://seer.cancer.govld/prost.html)
`
`1990
`1985
`1980
`1975
`Year
`88.5%
`75.0%
`70.2%
`66.0%
`5-Year Relative Survival
`SEER 9 Incidence & U.S. Mortality 1975-2013, All Races, Males. Rates are Age-Adjusted.
`
`1995
`95.7%
`
`2000
`98.8%
`
`2004
`99.7%
`
`2008
`99.1%
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`More About This Cancer
`
`
`
`10/3/2016
`
`More About This Cancer
`Cancer and the Prostate
`
`Cancer of the Prostate SEER Stat Fact Sheets
`
` (http://seer.cancer.gov/i/factsheets/prost-lg.jpg)
`Figure: Prostate and Nearby Organs
`This cancer forms in tissues of the prostate (a gland in the male reproductive system found below the bladder and in front of the rectum). The prostate surrounds
`the urethra, the tube through which urine flows. A healthy prostate is about the size of a walnut. If the prostate grows too large, it squeezes the urethra. This may
`slow or stop the normal flow of urine. Prostate cancer usually occurs in older men.
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`Additional Information
`
`Learn more about prostate cancer (http://www.cancer.gov/cancertopics/types/prostate)
`More Information
`Here are some resources for learning more about prostate cancer.
`
`About risk factors for prostate cancer (http://www.cancer.gov/types/prostate/patient/prostate-prevention-pdq#section/all)
`About symptoms and diagnosis of prostate cancer (http://www.cancer.gov/types/prostate/patient/prostate-treatment-pdq#section/all)
`About treatment options for prostate cancer (http://www.cancer.gov/types/prostate/patient/prostate-treatment-pdq#section/all)
`About clinical trials (http://www.cancer.gov/clinicaltrials)
`About preventing prostate cancer (http://www.cancer.gov/types/prostate/patient/prostate-prevention-pdq#section/all)
`About the health risks of smoking and ways to quit (http://www.cancer.gov/about-cancer/causes-prevention/risk/tobacco/quit-smoking-pdq#section/all)
`References
`All statistics in this report are based on statistics from SEER and the Centers for Disease Control and Prevention's National Center for Health Statistics. Most can be
`
`
`
`Cancer of the Prostate SEER Stat Fact Sheets
`10/3/2016
`All statistics in this report are based on statistics from SEER and the Centers for Disease Control and Prevention's National Center for Health Statistics. Most can be
`found within:
`
`Howlader N, Noone AM, Krapcho M, Miller D, Bishop K, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z, Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA
`(eds). SEER Cancer Statistics Review, 1975-2013, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2013/ (http://seer.cancer.gov/csr/),
`based on November 2015 SEER data submission, posted to the SEER web site, April 2016.
`Suggested Citation
`All material in this report is in the public domain and may be reproduced or copied without permission; citation as to source, however, is appreciated.
`
`SEER Cancer Statistics Factsheets: Prostate Cancer. National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/statfacts/html/prost.html
`(http://seer.cancer.gov/statfacts/html/prost.html)
`
`This factsheet focuses on population statistics that are based on the US population. Because these statistics are based on large groups of people, they cannot be used
`to predict exactly what will happen to an individual patient. To see tailored statistics, browse the SEER Cancer Statistics Review (http://seer.cancer.gov/csr/). To see
`statistics for a specific state, go to the State Cancer Profiles (http://statecancerprofiles.cancer.gov/).
`
`The statistics presented in this factsheet are based on the most recent data available, most of which can be found in the SEER Cancer Statistics Review
`(http://seer.cancer.gov/csr/). In some cases, different year spans may be used. Estimates for the current year are based on past data.
`
`Cancer is a complex topic. There is a wide range of information available. This factsheet does not address causes, symptoms, diagnosis, treatment, follow-up care, or
`decision making, although it provides links to information in many of these areas.
`
`The SEER Website is a service of the Surveillance Research Program, in NCI's Division of Cancer Control and Population Sciences
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