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`iViAILED
`FEB 2 R 1991
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`· , .... "' 1.1o·o. v•·riL:E
`JOARD OF PATENT APPEALS
`AND INTERFERENCES
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`Paper No.
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`14
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`U.S. DEPARTMENT OF COMMERCE
`Patent end Trademark Office
`
`Address: BOX INTERFERENCE
`Comn:issioner of Patents and Trademarks
`Washington. D.C. 20231
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`•
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`Telephone:
`Facsimile:
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`(703)557-4007
`(703)557-8642
`
`Applicants: Cabilly et al
`Serial No.: 07/205,419
`Filed: June 10, 1988
`For: RECOMBINANT IMMUNOGLOBIN
`PREPARATIONS
`Accorded Benefit of: u.s.
`S.N. 06/483,457, filed
`04/08/83, now Patent No.
`4,816,567, issued 03/28/89
`
`The case referred· to above has been forwarded to the
`
`Board of Patent Appeals and Interferences because it is adjudged
`
`to interfere with other cases hereafter specified. Attention is
`
`directed to the fact that this interference is declared pursuant
`
`to 37 CFR 1.601 et seq., effective February 11, 1985 (49 F.R.
`
`48416. 1050 O.G. 385). The interference is designated as No.
`
`102,572.
`
`By direction of the Commissioner of Patents and
`
`Trademarks and as required by 35 USC 135(c), notice is hereby
`
`given the parties of the requirement of the law for filing in the
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`Patent and Trademark Office a copy of any agreement "in
`
`connection with or in contemplation of the termination of the
`
`interference."
`
`Merck Ex. 1014, pg 612
`
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`r
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`Serial No. 205,419
`
`-2-
`
`The cases involved in this interference are:
`
`Junior Party
`Patentees: Michael A. Boss, John H. Kenten, John s. Emtage
`and Clive R. Wood
`
`Address: 20 Hunter Court, Huntercombe Lane North, Slough,
`Berkshire, SL1 60S, U.K.
`24 Avery Avenue, Downley, High Wycombe, Buckinghamshire,
`U.K.
`12 Benjamin House, Amersham Hill, High Wycombe,
`Buckinghamshire, U.K.
`'Whych Wood', Buddle Hill, North Gorley, Near
`Fordingbridge, Hampshire, U.K.
`
`Serial No.: 06/672,265, filed 11/14/84, now Patent No. 4,816,397,
`issued 03/28/89
`
`For: MULTICHAIN POLYPEPTIDES OR PROTEINS AND PROCESSES FOR THEIR
`PRODUCTION
`
`Assignee: Celltech Limited, Berkshire SL1 4DY, U.K., A British
`Company
`
`Attorneys of Record: Paul N. Kokulis, Allen Kirkpatrick,
`Lloyd J. Street, George T. Mobille, James L. Dooley,
`Alvin Guttag, Raymond F. Lippitt, G. Lloyd Knight,
`Carl G. Love, Lawrence A. Hymo, Akin T. Davis,
`Edgar H. Martin, William K. West, Jr., Kevin E.
`Joyce, Edward M. Prince, Donald B. Deaver, David W.
`Brinkman, George M. Sirilla, William T. Bullinger,
`·Dofiald J. Bird, Larry s. Nixon, James R. Longacre,
`Arthur R. Crawford, w. Warren Taltavull, Michael L.
`Keller, Charles R. Donohoe, Sherman o. Parrett,
`Robert A. vanderhye, Watson T. Scott, Peter w.
`Gowdey, Michael A. Lechter, Dale S. Lazar, James T.
`Hosmer and Glenn J. Perry
`
`Associate Attorney: None
`
`Accorded Benefit of: None
`
`Address: Cushman, Darby & Cushman
`Eleventh Floor
`1615 L Street, N.W.
`Washington, DC 20036
`
`Merck Ex. 1014, pg 613
`
`
`
`r ' . .
`
`Serial No. 205,419
`
`Senior Party
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`-3-
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`Applicants: Shmuel Cabilly, Herbert L. Heyneker,
`William E. Holmes, Arthur D. Riggs and
`Ronald B. Wetzel
`
`Address: 2038 s. Peck, Monrovia, CA 91016
`2621 Easton Drive, Burlingame, CA 94010
`29 Eastlake, Pacifica, CA 94044
`4852 St. Andres Avenue, La Verne, CA 91750
`76 Melrose Avenue, san Francisco, CA 94131
`
`Serial No.: 07/205,419, filed 06/10/88
`
`For: RECOMBINANT IMMUNOGLOBULIN PREPARATIONS
`
`Assignee: Genentech, Inc., South San FranciscQ, CA, A California
`Corporation
`
`Attorneys of Record: Walter H. Dreger, Thomas D. Kiley,
`Kate H. Murashige, Max D. Hensley and Janet E. Hasak
`
`Associate Attorneys: None
`
`Accorded Benefit of: u.s. S.N. 06/483,457, filed 04/08/83, now
`Patent No. 4,816,567, issued 03/28/89
`
`Address: Max D. Hensley
`Genentech, Inc.
`460 Point San Bruno Blvd.
`So. San Francisco, CA 94080
`
`I
`I
`
`Merck Ex. 1014, pg 614
`
`
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`Serial No. 205,419
`
`Count 1
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`-4-
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`A process for producing an Ig molecule or an
`immunologically functional Ig fragment comprising at least the
`variable domains of the Ig heavy arid light chains, in a single
`host cell, comprising the steps of:
`
`transforming said single host cell with a first
`{i)
`DNA sequence encoding at least the variable domain of the Ig
`heavy chain and a second DNA sequence encoding at least the
`variable domain of the Ig light chain, and
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`independently expressing said first DNA
`{ii)
`sequence and said second DNA sequence so that said Ig heavy and
`light chains are produced as separate molecules in said
`transformed single host cell.
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`The claims of the parties which correspond to this
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`count are:
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`Boss et al: Claims 1-18.
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`Cabilly et al: Claims 101-120.
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`MFD/raj
`
`. Downey
`er-in-Chief
`557-4003
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`Merck Ex. 1014, pg 615