TABLE 18 (continued)
`Hoy’s Cohesion Parameters for Liquids (and Solids as Subcooled Liquids) at 25°C
` 3111111619
`
`Liquid
`
`Mfg 11111!"
`
`1111; cm"
`
`8,
`
`S,
`
`34.2
`1442
`101.2
`911.1
`33.2
`1 12.2
`1411.2
`
`11.672
`11.363
`0.743
`0.362
`11.749
`11.775
`11.991
`
`13.9
`14.9
`14.2
`13.9
`15.1
`15.4
`13.9
`
`3.3
`1.1
`7.3
`7.1
`3.2
`2.6
`10.5
`
`5,,
`
`3.0
`3.0
`3.3
`7.7
`0.0
`0.0
`4.7
`
`8,
`
`14.7
`16.3
`16.3
`11.7
`15.4
`15.7
`13.1
`
`2,3.z11mc13y1—1—11u1en6
`3,3-111m11y13u1y1 6661616
`1.3-Dinmlhylbutylmnine
`1111116111311 ce116361v6-I
`1.I-Dinnethylcyclopcntmme
`l,I—DimBtb}'IByI2I0heJ{a£IE
`2,5—r11m613y1-3 .4-11111y11m211.pyran-2.3a:-
`baxynldehydc
`11111111111311 1111161666
`2.6-1:111n6111y1—1.4-111611116
`N,N-Dimelhyiethannlamine
`N,N-Di113efi1yI—2—ethy1hexyIaminc
`2,5—Di1:r1ethyIfI:ra13
`2.2.111111313y1116p1a116
`2,3—DimEIh)I'Ihepta!!c
`2,4-Dimflliylhcptznc
`2,5.131mez11y11mp1me
`2.6-Dinwthylineptane
`3,3-Dimcthylheptann
`3,4-I)ir.11ethylhcp1:arII:
`3.5-1311116111,-1116111111111
`4,4-Dimelhylheptane
`2,6—Dir11elhyl—4-hcptanol
`2,6-Dimellryl-4—heptyI 11661313
`2.2—DimsIhylheJIanc
`2,3-Dimedaylhcxane
`
`2,4n1m631y1116me
`2.5-Dinlcthylhexanc
`3,3-l3'ime‘lhyI21e11ane
`3,4—Dimet21yI'I1ex1m1:
`2.3-Djmethyl-6-isotIutyl-4—111)1Ian{12
`Dinmthylisopmpunolanéne
`1111331311 1113111326
`2,6-Dimcthyllnolpholine
`2.2-Di!11cLI1}|'I£X31&l1c
`2.3-Dimethyiomane
`2.4-Dimcshyltx.-tane
`2.5—Dim:lhy1oc1ar1B
`2,6-Di1n£rhyIoct&nc
`2.7-111m6111y16c1ane
`3.3-nimahyxmm
`3,4-Diflmlilyiflcifinfi
`3,5-111m6111y16c1a11e
`3,6-Dirrucdayioclanc
`4.4016161331661666
`4.5-131mez11;.«16cmm
`2,3-Disnethylpcmaldehyde
`2,2—Dim13!hyI‘pea'1lane
`2,3—Dim=th31lpenta11:
`2,4-Dimethyipcntune
`3,3-Dimclhylpeniane
`2.3-mam-.my1p3mam1
`2.3—Dimefl'|yIpem1:naI
`111316111311 151111161116
`
`‘
`I
`
`'
`
`5 M
`
`I
`
`|_
`I
`
`I
`
`I
`I
`'
`'
`I
`1
`.
`1
`I
`I
`L
`I
`.
`
`I
`
`.
`I
`'
`
`I
`
`'
`.
`
`-
`'
`i
`
`'
`
`'
`I
`.
`
`-
`
`-
`
`.
`
`1
`.
`'
`1
`I II
`-
`I
`
`'
`F
`I
`I
`.
`-
`I
`-
`
`_
`I
`'
`
`'
`
`.
`'
`
`,
`1
`
`-
`
`.
`
`.
`-
`
`I
`.
`-
`
`116.1
`116.2
`39.1
`151.3
`96.1
`123.3
`123.3
`123.3
`123.3
`123.3
`123.3
`123.3
`123.3
`123.3
`144.3
`136.3
`114.2
`114.2
`
`114.2
`114.2
`114.2
`114.2
`223.4
`103.2
`144.1
`115.2
`142.3
`142.3
`142.3
`142.3
`142.3
`142.3
`142.3
`142.3
`142.3
`142.3
`142.3
`142.3
`114.2
`100.2
`103.2
`11111.2
`1011.2
`116.2
`112.2
`194.2
`
`3.976
`0.939
`0.332
`0.764
`11.394
`0.705
`0.121
`0.11 1
`0.110
`0.104
`11.720
`0.726
`0.113
`0.720
`0.3117
`0.347
`0.690
`0.7117
`
`0.695
`0.633
`0.7115
`0.7114
`0.322
`0.345
`1.146
`11.923
`0.719
`0.732
`3.121
`11.731
`0.723
`0.719
`0.734
`11.741
`0.731
`0.131
`0.132
`0.742
`0.323
`0.663
`0.690
`0.667
`0.6311
`0.337
`0.337
`0.119
`
`10.6
`15.1
`13.5
`15.3
`15.11
`14.9
`15.3
`15.0
`15.1
`15.0
`15.1
`15.4
`15.1
`15.11
`14.3
`14.4
`14.5
`15.0
`
`14.7
`14.6
`14.7
`14.9
`13.3
`12.6
`14.5
`16.4
`14.9
`15.3
`14.9
`15.1
`15.1
`15.11
`15.3
`15.4
`15.2
`15.2
`15.2
`15.4
`14.5
`14.1
`14.3
`14.2
`14.5
`14:3
`14.1
`15.9
`
`12.7
`3.3
`3.5
`3.1
`7.11
`0.0
`11.0
`0.11
`0.11
`0.11
`0.11
`0.11
`0.11
`0.11
`6.7
`6.1
`0.11
`0.11
`
`0.11
`0.0
`0.0
`0.0
`5.3
`1.1
`12.1
`111.0
`0.0
`0.0
`0.0
`11.0
`11.0
`0.0
`0.0
`0.0
`0.0
`0.11
`0.11
`0.11
`7.7
`0.11
`0.11
`0.0
`0.0
`3.2
`3.7
`12.6
`
`11.7
`4.3
`14.0
`1.6
`4.3
`11.0
`11.0
`0.0
`11.0
`0.0
`0.11
`0.0
`0.0
`0.11
`9.2
`2.2
`0.0
`0.11
`
`0.11
`0.11
`0.11
`0.11
`6.9
`11.2
`11.3
`2.3
`0.11
`0.0
`0.0
`0.0
`0.0
`0.0
`11.0
`11.0
`11.0
`11.0
`11.0
`0.0
`6.3
`11.11
`0.0
`0.0
`0.0
`12.0
`6.1
`9.7
`
`211.3
`13.2
`21.2
`15.7
`17.9
`14.9
`15.3
`15.0
`15.1
`15.11
`15.1
`15.4
`15.1
`15.0
`13.3
`15.3
`14.5
`15.0
`
`14.7
`14.6
`14.7
`14.9
`16.3
`13.5
`22.3
`19.3
`14.9
`15.3
`14.9
`15.1
`15.1
`15.11
`15.3
`15.4
`15.2
`15.2
`15.2
`15.4
`17.6
`14. 1
`14.3
`14.2
`14.5
`211.3
`17.3
`22.5
`
`YLAN PHARMS. INC. EXHIBIT 1044 PAGE 101
`
`

`
`
`
`TABLE 18 (continued)
`Ho}/’s Cohesion Parameters for Liquids (and Solids as Subcooled Liquids) at 25“C
`
`
`fi!‘1\viPa“'
`
`
`Liquid
`
`mg mo!"
`
`PIE cm‘!
`
`at
`
`3;
`
`an
`
`51
`
`Dimethyl pimelaic
`2.2—Dime£hylpmpauc
`2,5—1'}imethylteu'a1:ydrofuran
`1,4-Dioxane, dicthyiem oxide
`1,3-Dimcolane
`Dipemene
`Diphcnyl ether
`Diphcaylmelhsne
`1,1-Dipropoxyethane
`Dipmpylarnjne
`Dipropylcnc grycul, Oxyhispmpanol
`Dipmpylencrriaminc
`Dipmpyi keiom-.
`2.3~Di{.hiabutzne
`Divinyl Ca.rbi1o19
`Dodeclmc
`
`1-Dodacanol, lauryf alcohol
`2-Dodecanul, 2-dodecyl alcohol
`Epichlomhychin, (chloromr.-1hy1)oxira:le
`3,4-Epoxy—1-bulcnc
`Ethanol
`
`2-Ethoxy-3,4-dihydxu-I ,2-pyran
`1—EIho.xycIhoxy-2—pmpanol
`3-Ethoxy-4-cthyloaaml
`2-Ethaxy-4-methyl-3.4-dihyximpyran
`5-Elhoxy—3-xncdlylpenlaml
`2-1"Lthox)'-4—meLhy1£cE:a.1zydzDpyxan
`i—Ezhoxy-2-propane]
`3—E£hoxypmpa|m1
`3-Ethoxypmpionaldeilyde
`3-Erhoxypmpionic acid
`3-Eihoxypmpyl uuam
`2-Ethoxy-mpmpyj-5-ethyl-3,4—dihydmpyran
`2—Efl1oxy:eu'a!:ydropy:an
`Eflaoxyniglycol
`Ethyl acetate
`Ethyl aceioacezazc
`Ethyl amyialc
`Ethyi amyl ketonn
`N-Eshylauiline
`Ethylhcnzenn:
`Ethyl benzoate
`Ethyl bmmide, sec Bromoethane.
`2-Ethyl-1,3-humdiens
`2-Ethylbutanol
`2-Ethyl-Lhutcne
`2-Etlayibutyl ucclate
`N-Ethyibutylamins
`2—Et11ylb::tyl Ca:bi:ol"°
`2—Ethylbutyl Ceflosolve“
`Ethyl bulyl -tther
`2-Ethylbutyl 2-cshylbutyrazc
`2-Em}-lbmyi 2—n:thyEhexnnoam
`2—§E£hyl1Ju1yl hexanoatc
`
`188.2
`72.2
`100.2
`88.1
`64.!
`136.2
`170.2
`163.2
`146.2
`101.2
`134.2
`131.2
`114.2
`94.2
`158.2
`170.3
`186.3
`186.3
`92.5
`70.1
`46.1
`128.2
`148.2
`202.3
`142.2
`146.2
`144.2
`104.2
`104.2
`102.1
`118.1
`158.2
`198.3
`130.2
`178.2
`88.1
`130.1
`100.1
`128.2
`121.2
`106.2
`150.2
`
`1.034
`0.534
`0.325
`1.023
`1.053
`0.336
`1.06!
`I.{X30
`0.825
`0.732
`1.016
`0.393
`0.311
`1.055
`0.964
`0.744
`0.529
`0.325
`1.163
`0.369
`0.785
`0.963
`0.950
`0.379
`0.927
`0.394
`0.903
`0.392
`0.912
`0.911
`1.041
`0.957
`0.914
`0.933
`1.015
`0.894
`1.019
`0.915
`0.316
`0.957
`0.862
`1.041
`
`14.3
`12.5
`15.6
`15.3
`14.8
`16.3
`17.4
`17.2
`13.9
`14.0
`12.2
`13.2
`14.6
`13.9
`14.3
`16.2
`15.5
`13.7
`15.9
`14.3
`1.2.6
`14.3
`13.4
`14.4
`14.9
`14.4
`15.4
`13.0
`14.0
`13.5
`16.5
`14.5
`14.9
`14.9
`13.1
`13.4
`13.3
`13.3
`14.5
`17.1
`16.5
`15.7
`
`9.4
`0.0
`6.5
`10.1
`11.3
`5.3
`11.2
`9.4
`6.2
`5.2
`10.3
`1 1.5
`7.5
`13.4
`9.0
`0.0
`6.5
`5.3
`12.3
`9.3
`11.2
`3.3
`8.5
`6.4
`3.3
`8.6
`7.4
`3.5
`3.7
`9.7
`11.5
`3.2
`6.3
`7.7
`3.8
`8.6
`11.1
`9.3
`7.2
`10.5
`7.4
`10.6
`
`9.6
`0.0
`0.0
`7.9
`13.9
`0.0
`0.0
`0.0
`5.1
`5.3
`17.4
`10.6
`6.9
`5.4
`9.4
`9.0
`10.3
`9.2
`10.5
`3.6
`20.0
`4.9
`12.3
`9.9
`3.7
`12.5
`2.9
`12.8
`14.3
`10.5
`16.5
`3.2
`4.3
`4.2
`13.5
`3.9
`10.2
`7.9
`5.7
`7.7
`0.0
`6.3
`
`20.0
`12.5
`16.9
`20.7
`2.3.2
`17.3
`20.7
`19.5
`16.0
`16.3
`23.6
`20.5
`17.3
`20.1
`19.3
`16.2
`20.0
`17.4
`22.7
`19.7
`25.1
`17.9
`20.4
`10.5
`17.4
`20.9
`17.3
`20.1
`22.1
`19.7
`26.0
`18.6
`17.0
`17.3
`20.3
`13.2
`20.1
`38.0
`17.2
`21.5
`1.3.1
`19.9
`
`82.2
`102.2
`84.2
`144.2
`101.2
`190.3
`146.2
`102.2
`200.3
`228.4
`200.3
`
`0.713
`0.329
`0.634
`0.374
`0.735
`0.933
`0.390
`0.745
`0.861
`0.353
`0.363
`
`14.3
`14.4
`14.3
`14.6
`13.9
`13.3
`13.7
`14.3
`14.3
`14.7
`14.4
`
`5.6
`3.5
`3.9
`7.0
`6.2
`7.4
`7.3
`4.8
`5.3
`5.4
`5.3
`
`0.0
`13.0
`3.1
`5.3
`5.9
`11.2
`11.5
`4.5
`4.7
`4-9
`5.5
`
`15.4
`21.2
`15.2
`17.0
`16.3
`13.9
`19.4
`15.7
`16.1
`16.5
`16.4
`
`
`
`
`
`MYLAN PHARMS. INC. EXHIBIT 1044 PAGE 102
`
`

`
`5°C
`
`8,
`
`259
`12.5
`15.9
`211.7
`23.2
`17,3
`211,-;
`19,5
`15.0
`15.3
`23.5
`20.5
`17.3
`20.1
`19.3
`I6_2
`20.0
`17.4
`22.7
`19.7
`25.1
`17.9
`20.4
`13.5
`17.4
`20.9
`17.3
`20.1
`22.1
`19.7
`25.0
`13.5
`17.0
`17.3
`20.3
`3.2
`10.1
`3.0
`7.2
`:1.5
`3.1
`9.9
`
`5.4
`1.2
`5.2
`7.0
`5.3
`3.9
`9.4
`1.7
`1.1
`1.5
`1.4
`
`'
`I
`
`1
`
`I
`
`TABLE 18 (continued)
`H0y’3 Cohesion Parameters for Liquids (and Solids as Subcooled Liquids) at 25°C
`
`513119“
`
`129
`
`Liquid
`
`Mfg mo!“
`
`pl;1:1r1'°
`
`B,
`
`13111311 1511191 11515115
`2-Edlyibutyraldchydc
`B11131! butyrah-.
`2-1511131111111,-7115 5515
`2-E11.y1cro155a15e11yde
`2111311-15155515
`‘E.111y}cyclnh1:xa1:1n
`N—EL!1ylcyc1ohe11yIamine
`iithylcyclopemane
`N-Bthyldiethanohunim
`N-Blhyldiisnpmpanolanline
`4-13111311-2,5411111e111,-1.111511111511115
`3-EtI1yl—2.2-dimethyipcntsne
`3—EIhyl—2,3—di11115fl1yIpcn111n1:
`Ethyi 2,S—endon1:1i1yi:r1e-3-cycIei1::xane1:.3r—
`buxylate
`Ethylem: 55151511701111. 24111515501155:
`Ethylene cyanohydrin
`Ethyienediaauine, 1.24.-11555511111155
`13.1111-11:55 glycol, 1.241111511511151
`N-Ethylelhanolamine
`15111111 511151, 315111511 51115:
`13111311 3—e1hoxyl3111y-1-ale
`1311131 3-5111511;-11115111511515
`3-5115113551555
`'
`4-17.111111115111111-11:
`5-Ethyl-3-hcpleu—Z—c:11e
`2-Elhylircxaldehyde
`3-Ezlzylhexane
`2—E.£I1yIha111maic acid
`2—EthyIhaxa110l
`2-Eahyl-I-hexene
`2-Ethylhexyl 55:11::
`2-E111y111exy1 55111115
`2-Ezhylhexylamine
`2—E!hyI!1.axyl 1211111111111-1
`2a111y111e.11y1 05115551159
`2.311141111111111 5111511115
`2-511111111511111 515151111.-.
`2-Ethyihcxyl 2-cthylbutyrate
`2-E£byIhexyl—2—elhylhzxa11oate
`2—E!hyIhexyl 1151555515
`3-(2-EtI1y]hexoxy}p1'opyIamine
`.2—E£hyI|1:x)'l 45551555515
`E1hy1'1dc11ea1:e£o11e
`N-Eznyusopmpuommne
`Ethyl inn-propenyl ether
`511111 isopropyl ether
`N—EthyI-01—rr1ol!'1y|he21zyInmine
`2-5051-2-51501;-1-1.3-5151515115
`3-E111y1.2.me111y111ep1an.-.
`3-Ethyl-3-lncfiiyllicplane
`3-F1hy1—4-15515315551155
`4—E1.I3yI—2—me!i1ylhepIax1e
`
`114.2
`100.2
`115.2
`115.2
`93.2
`114.1
`112.1
`127.2
`93.2
`133.2
`151 .3
`135.2
`123.3
`123.3
`155.2
`
`30.5
`71.1
`50.1
`52.1
`39.1
`74.1
`150.2
`145.2
`123.3
`123.3
`140.2
`123.2
`114.2
`144.2
`130.2
`112.2
`172.3
`134.3
`129.3
`213.3
`174.3
`143.7
`193.3
`223.4
`255.4
`223.4
`187.3
`212.3
`34.1
`103.2
`35.13
`100.2
`149.2
`1 15.2
`142.3
`142.3
`142.3
`142.3
`
`0.313
`0.310
`0.374
`0.919
`0.352
`0.913
`0.733
`0.342
`0.751
`1.010
`0.940
`0.375
`0.730
`0.749
`1.021
`
`1.197
`1.041
`0.903
`1.110
`0.913
`0.703
`0.924
`0.943
`0.722
`0.725
`0.341
`0.315
`0.703
`0.902
`0.329
`0.722
`0.357
`0.331
`0.734
`0.913
`0.330
`0.377
`0.331
`0.353
`0.355
`0.1159
`0.843
`0.374
`0.1150
`0.332
`0.754
`0.305
`0.905
`0.932
`0.741
`0.745
`0.743
`0.731
`
`14.2
`14.0
`13.3
`17.4
`14.4
`14.0
`15.1
`15.3
`15.9
`13.2
`12.5
`15.3
`14.9
`15.3
`14.7
`
`12.0
`11.1
`12.5
`10.1
`14.3
`13.4
`14.1
`14.3
`15.4
`15.5
`15.0
`14.3
`15.2
`17.4
`15.1
`15.0
`14.3
`13.9
`14.3
`13.9
`13.7
`15.5
`15.4
`14.1
`14.7
`14.5
`14.2
`14.5
`14.3
`13.5
`14.1
`15.3
`15.4
`15.4
`15.4
`15.4
`15.5
`15.2
`
`5,,
`
`7.4
`7.9
`7.5
`9.3
`9.5
`3.3
`2.5
`7.0
`3.3
`9.5
`3.4
`5.5
`0.0
`0.0
`7.7
`
`13.3
`15.2
`14.0
`15.1
`10.5
`5.3
`3.0
`3.5
`0.0
`0.0
`7.3
`7.1
`0.0
`3.3
`7.7
`3.5
`5.3
`5.3
`5.5
`7.1
`5.7
`5.4
`5.7
`5.3
`5.1
`5.4
`6.7
`5.3
`9.9
`9.5
`5.9
`5.1
`3.3
`3.5
`0.0
`0.0
`0.0
`0.0
`
`5,,
`
`5.9
`7.2
`5.4
`12.9
`7.5
`7.5
`0.0
`3.0
`0.0
`13.2
`14.1
`2.1
`0.0
`0.0
`10.9
`
`19.5
`24.7
`15.9
`29.3
`17.3
`5.5
`5.7
`3.0
`0.0
`0.0
`5.5
`5.5
`0.0
`11.5
`12.0
`0.0
`5.4
`4.5
`5.9
`10.5
`10.5
`2.4
`5.2
`4.5
`4.7
`5.5
`6.8
`5.3
`9.7
`14.5
`2.7
`5.2
`4.3
`0.0
`0.0
`0.0
`0.0
`0.0
`
`5,
`
`17.4
`17.5
`17.0
`23.5
`13.9
`13.2
`15.3
`17.5
`15.2
`24.4
`20.5
`17.2
`14.9
`15.3
`19.3
`
`25.5
`31.0
`25 .3
`34.9
`25.1
`15.4
`17.5
`13.4
`15.4
`15.5
`13.1
`17.2
`15.2
`22.5
`20.3
`15.5
`17.0
`15.1
`17.3
`13.9
`13.5
`15.5
`17.9
`15.7
`15.2
`15.4
`17.1
`17.0
`19.9
`22.1
`15.9
`17.3
`13.2
`17.5
`15.4
`15.4
`15.5
`15.2
`
`_
`
`I
`!
`I
`i
`1
`1
`f‘
`I
`',
`
`-
`!
`-
`
`'
`-
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`
`.
`I
`
`I
`
`.
`
`!
`|
`|
`
`I
`
`
`
`MYLAN PHARMS. INC. EXHIBIT 1044 PAGE 103
`
`

`
`
`
`-
`.'
`
`130
`
`CRC Handbook ofSoiubflily Parameters and Other Cahesion Parameters
`
`H£1y’s Cohesion Parameters for Liquids (and Solids 5111 Subcnnled Liquids) at 25°C
`
`Liquid
`4—ErhyI—3—m1:£hylhepfl1nc
`4-Etllyl-4—mcd1yZ]1eptane
`5-E£hyI—2—mcthy1hcpI1mc
`5-Ethyl-3~mcthylI1q}Ia£1e
`3—££hyl-2—1II0£!1y1bcxaue
`3-E1hy1-3-memyzzmane
`4-Eth)-I-2-met11yJ.h1:xa11e
`4-Elhyl-3~me£hylhexa.11c
`3-ELhy!—2—mc!hyipe11tanc
`3-Ethyl-3—mc¢hyIpen1a11c
`2—Efl'1y1-3—1nezl1)r}-l,5—pe:1I1mcdio}
`5-Ethyl-2—mefl1ylp1'peridi12e
`7—E111y1-2-m61hy1-4-u6d6cano1
`N—E£byimm'ph0I.i:1c
`5-Efl1y}—2-nonaszonc
`5-13111y1-2.6666661
`3-13111y16cza.-16
`4-Ethyincranc
`4—Ethy!0clan-3}
`3~E¢hy}p1:11I3ne
`2—5x11y1-1.566111116611161
`Ethyi pmpionare
`2-Ed1yi—3-propylacroicin
`2-Ethy!-3—propylacry}ic 61:16
`2-Ethyl—2-propylhcxanoi
`Ethyl pm-pyf 11616116
`3-Ezhyz-4-pxnpyzseuahyctxopyran
`m—Efl.1}'Zsz)'1'er1e
`m-130911610666
`6-13.111311115111661:
`p-Ethyltolucne
`Fl1.IOrOhfllJ.2BI2B
`2—F0rmyl—3.4—dihydm—2H—pyza.a
`Glycerol, l,2,3~propane0'ioI
`°G1yoe161 613661.-111:
`11131661 013661136
`0131661 616166166616
`Hcptane
`2,4—Hep1ane1iinI
`I-Heptanol
`211ep6u1o1
`3-116pumo1
`1-116151611:
`cs:-2-Hcpcenc
`trans-2-Hcptcnc
`(‘Li-3-Hcpflfllle
`!ran.f—3-Heptcfle
`3-Heplfln-2-one
`2-Hfipty} 8.08131:
`3-Heplyl 6661411:
`Hcptyfbcrxmnc
`3—Heptyl carbimzv
`3-I-Ieptyl c'6116s61ve°
`2,4—f-Eexzzdienai
`Hexaldehyde
`
`Mfg mo!"
`142.3
`142.3
`142.3
`142.3
`123.3
`123.3
`123.3
`123.3
`114.2
`114.2
`146.2
`127.2
`214.4
`115.2
`170.3
`172.3
`142.3
`142.3
`153.3
`100.2
`132.2
`102. 1
`126.2
`142.2
`172.3
`100.2
`156.3
`132.2
`120.2
`120.2
`120.2
`96.1
`112.1
`92.]
`213.2
`146.1
`174.2
`100.2
`132.2
`116.2
`116.2
`116.2
`93.2
`93.2
`93.2
`93.2
`93.2
`112.2
`153.2
`153.2
`176.3
`204.3
`160.3
`96.1
`100.2
`
`pig cm"
`0.743
`0.747
`0.731
`0.733
`0.726
`0.736
`0.713
`0.737
`0.714
`0.722
`0.962
`0.1134
`0.331
`0.903
`0.333
`0.1131
`0.735
`0.735
`0.334
`0.693
`0.964
`0.334
`0.346
`0.943
`0.350
`0.311
`0.1174
`0.339
`0.359
`0.375
`0.359
`1.015
`1.070
`1.2.58
`1.153
`1.099
`1.042
`0.679
`0.926
`0.319
`0.313
`0.317
`0.692
`0.703
`0.696
`0.697
`0.693
`0.342
`0.357
`0.360
`0.351
`0.924
`0.330
`0.333
`0.1109
`
`6,,
`15.6
`15.6
`15.1
`15.3
`15.2
`15.2
`15.0
`15.4
`15.0
`14.9
`14.2
`15.7
`14.3
`16.6
`15.1
`14.3
`15.3
`15.3
`14.9
`15.0
`13.3
`14.0
`14.9
`13.9
`13.9
`13.9
`16.9
`16.3
`16.4
`16.3
`16.4
`15.4
`13.3
`9.3
`14.9
`14.4
`14.1
`15.3
`13.4
`15.1
`14.6
`14.6
`14.6
`15.0
`14.9
`14.3
`14.3
`15.5
`14.6
`14.5
`16.5
`13.4
`13.3
`15.1
`14.2
`
`6111491113
`8,
`0.0
`0.0
`0.0
`0.0
`0.0
`0.0
`0.0
`0.0
`0.0
`0.0
`10.7
`6.9
`5.6
`7.6
`6.3
`6.1
`0.0
`0.0
`7.0
`0.0
`10.11
`3. 1
`3.4
`10.1
`6.6
`7.9
`5.2
`7.7
`6.7
`6.9
`6.6
`9.0
`12.0
`15.4
`11.6
`11.2
`9.7
`0.0
`9.9
`3.0
`7.4
`7.5
`3.6
`3.4
`3.1
`3.3
`3.1
`9.0
`6.6
`6.6
`5.6
`7.2
`6.9
`10.4
`7.9
`
`8,,
`0.0
`0.0
`0.0
`0.0
`0.0
`0.0
`0.0
`0.0
`0.0
`0.0
`16.9
`1.6
`3.2
`0.7
`6.3
`9.6
`0.0
`0.0
`1 1.0
`0.0
`13.9
`7.3
`6.6
`12.9
`9.7
`7.3
`0.0
`0.0
`1.5
`0.0
`2.1
`5.2
`9.6
`31.4
`11.2
`10.6
`9.2
`0.0
`16.11
`13.0
`11.7
`11.3
`2.7
`2.3
`2.9
`2.5
`2.3
`6.4
`4.9
`5.0
`0.0
`10.7
`10.7
`11.2
`3.2
`
`6,
`15.6
`15.6
`15.1
`15.3
`15.2
`15.2
`15.0
`15.4
`15.0
`14.9
`24.5
`17.2
`17.4
`13.3
`17.5
`13.3
`15.3
`15.3
`19.3
`15.0
`25.3
`17.9
`13.3
`25.1
`13.2
`17.6
`17.6
`13.5
`17.3
`111.1
`17.3
`13.6
`20.6
`36.2
`22.0
`21.1
`19.4
`15.3
`23.7
`21.5
`20.1
`20.2
`15.3
`15.6
`15.5
`15.4
`15.3
`19.0
`16.3
`16.7
`17.4
`13.6
`13.4
`21.5
`13.2
`
`
`
`MYLAN PHARMS. INC. EXHIBIT 1044 PAGE
`
`104
`
`

`
`
`
`——
`
`5‘
`15.6
`
`15-5
`15-1
`15.3
`15-2
`15-2
`15-11
`15-4
`15-0
`1‘-9
`24-5
`17-3
`17-4
`18-3
`17-5
`111-3
`15-11
`15-3
`19-11
`151°
`25-3
`17-9
`13-3
`25-1
`13-2
`17-5
`17-5
`13-5
`17-3
`11‘-1
`17-3
`13-'5
`29-5
`35-3
`22-‘1
`21-1
`19-4
`153
`23-7
`21-5
`311‘-1
`21’-3
`15.3
`'5-5
`15-5
`15-4
`15-3
`
`I6’?
`-7-‘1
`3-5
`11-“
`-1-5
`3-2
`
`;
`.-"
`3
`1;
`J
`
`I
`
`1
`
`I
`
`.1
`5-
`
`-
`
`_
`.
`:'
`;
`1
`
`'.
`
`TABLE 18 (continued)
`Hoy’s Cohesion Parameters for Liquids (and Solids as Subcooled Liquids) at 25‘’C
`
`1.166111
`
`M1; !‘|1I'lI—1
`
`pig 6614
`
`8.1
`
`6,
`
`3.
`
`3.
`
`31141169
`
`116.1666
`2,.=6116x66116161
`g,5.;16m6¢16n6
`116666616 6616
`1-11666661
`2-H€X8.l1DI
`3-Hc,..,,,,_~.1
`14166666
`Li!‘-2—H€Xcl‘Ifl
`mm-2-1166666
`._-1-6.3.116;6n6
`1ms.3.H6x666
`11611y166616n6
`1166,11 Kfylfle
`116-.1y1am1n6, 1-16-6166661166
`1«166y1666 g1y661
`1166371666 glycol 616661616
`116xy1 Ca:bi1ol‘11
`Hexyl cc116661v69
`Hcxy] 611166116, 14131616361666
`1-16xy1 2-6111;-11m1yz616
`Hexyl 6111371 C61611619
`116113.11 2611ay166x666616
`11611371 166666616
`N-(2-11ydmxy6111y1)morp11o1166
`N-(2-Hyd1'oxycd1yl)piperidim'.
`1v-(2-1-1ydmy6111y1)p16py1666316msn6
`16666671 61661161. 3-Jlneihyl-I—bI.l‘[El10I
`.1'ec—I3oa1nyla.Ic0l10l, 3-lnclhyl-2-bufflnfll
`1661161311 6661616
`Ifiob!.l1'yIfic!')|'I&I.e
`1666616661, 2-mc111y1-1-p1op6661
`16611611;-1 11666666
`1666u1y1 c6116661v6¢
`16636131666 661616
`Ififlhutyl Ilfiiltyl 1166666
`1s61m1y1 ifi0bIl£)|'l'flIe
`Isobmyraldehydc
`ISOb‘1it)'I'iC 661:1
`Isotmtyronitrile
`1963666661
`16666161161
`16661161666
`16666666, 2-166111311-1,3-11616136116
`Isopropyi 6661616
`lsnptflpyl 666166661616
`Isopropyl alcohol, see 2-propnnol
`Isopropylamme, sec 2-propanammc
`166pr6py1666z666
`lsopmpyl 116666616
`1s6p.r6py1cy616116x666
`1s6pr6py16y616p661666
`N—!snpfOpyIdi1.S0‘prOpfln0Ia111§nc
`166pmpy1611161. 2,2’-6666166166666
`
`36.2
`113 .2
`114.1
`116.2
`102.2
`102.2
`1112.2
`34.2
`34.2
`34.2
`114.2
`34.2
`144.2
`156.2
`101.2
`113.2
`202.3
`190.3
`146.2
`120.6
`200.3
`213.3
`223.4
`200.3
`131.2
`130.2
`1 13.2
`33.2
`33.2
`116.2
`123.2
`74.1
`134.2
`113.2
`72.1
`134.3
`144.2
`72.1
`33.1
`69.1
`153.3
`130.2
`133.2
`68.1
`102.1
`144.2
`
`59.3
`120.2
`164.2
`126.2
`112.2
`175.3
`102.2
`
`11.654
`0.957
`11.967
`0.923
`0.316
`0.310
`0.314
`0.663
`0.631
`0.673
`0.674
`0.671
`0.369
`6.333
`0.762
`0.913
`0.994
`0.929
`0.333
`0.373
`0.356
`6.331
`0.353
`0.353
`1.063
`1.056
`0.933
`0.306
`0.313
`0.366
`0.334
`0.793
`0.343
`0.337
`0.301
`0.313
`0.349
`0.734
`0.943
`0.765
`0.335
`0.327
`0.917
`0.675
`0.366
`0.934
`
`0.68]
`0.357
`1.005
`0.797
`0.771
`0.935
`0.713
`
`14.9
`14.2
`13.6
`17.2
`15.0
`14.4
`13. 5
`14.4
`14.6
`14.6
`14.4
`14.5
`14.9
`14.7
`14.2
`12.5
`13.4
`13.9
`13.3
`15.6
`14.3
`14.3
`13.3
`14.7
`15.3
`15.0
`15.0
`15.2
`14.0
`14.5
`14.1
`14.4
`15.7
`13.9
`15.7
`14.7
`14.2
`13.1
`15.4
`13.3
`14.4
`14.4
`16.4
`13.7
`14.3
`13.4
`
`12.6
`16.2
`15.6
`16.0
`15 .6
`12.7
`13.6
`
`0.0
`10.7
`11.6
`9.2
`3.5
`7.9
`7.7
`3.9
`3.5
`3.3
`3.5
`3.3
`7.0
`7.5
`7.1
`11.4
`3.7
`7.5
`7.2
`6.0
`5.7
`6.1
`5.2
`5.3
`3.7
`11.0
`12.3
`9.3
`3.4
`7.3
`3.4
`9.3
`6.3
`7.6
`3.4
`6.0
`7.0
`9.0
`9.9
`10.6
`6.9
`7.3
`9.4
`5.3
`3.4
`10.4
`
`3.6
`6.9
`10.0
`2.5
`3.1
`3.2
`4.7
`
`11.0
`19.3
`11.6
`13.3
`13.7
`12.3
`11.6
`0.0
`3.1
`2.9
`3.4
`3.2
`6.4
`6.6
`6.9
`16.3
`7.0
`12.0
`12.1
`4.0
`5.2
`7.2
`5.2
`6.1
`13.3
`15.3
`19.2
`14.1
`12.4
`5.1
`5.7
`15.0
`0.0
`12.6
`1.3
`3.6
`0.0
`3.4
`16.2
`10.6
`10.7
`12.9
`3.2
`4.0
`5.7
`3.5
`
`7.0
`0.0
`3.9
`0.0
`0.0
`13.2
`1.5
`
`14.9
`26.2
`21.1
`23.9
`22.0
`20.5
`19.4
`15.0
`15.3
`15.2
`15.2
`15.2
`17.7
`17.3
`17.3
`23.1
`17.4
`19.11
`19.7
`17.2
`16.2
`17.1
`15.6
`17.0
`22.4
`24.1
`27.3
`22.7
`20.5
`17.2
`17.4
`23.0
`16.9
`20.2
`17.3
`16.3
`15.3
`17.9
`24.5
`20.1
`19.3
`20.7
`19.2
`15.3
`17.6
`19.0
`
`15.8
`17.6
`13.9
`16.2
`15.9
`20.1
`14.4
`
`-_
`
`.
`3
`I-
`
`_
`1f
`I
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`
`:
`.
`I
`1
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`
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`
`I
`. "
`-
`;
`
`=
`
`!
`E
`'
`;
`
`1
`
`
`
`MYLAN PHARMS. INC. EXHIBIT 1044 PAGE 105
`
`

`
`I32
`
`CRC Handbook of.S'o!ub1'Ii{y Parameters and Other Cohesion Parwnerers
`
`TABLE 18 (continued)
`Hoy’s Cohesion Parameters for Liquids (and Solids as Snbcooled Liquids) at 25°C
`
`
`
`Llqaid
`N—1sa;u1)pyIis0propano1anI1ne
`4—1sapropy1heptzne
`Isupmp)-1 6-me1hy1—3-cyclohexemcarboxybmc
`.N—Isepmpy1morpbo1ir1e
`Lam)-1 31031101, see 1-Dodecanoi
`Mcsityi oxide
`Methax:-qrledchyde
`Methacrylic acid
`Meflaaliyi cyanide
`Methanol
`1-Mcflwxy-1.3-buzadiene
`3-Mexhoxylmtanol
`3—Me£hoxybu1y1 acetate
`3-Methoxybutymldehyde
`4—Mcl11oxy—2,6-dipmpyl-1,3~c1io;xane
`4—Me£boxy4~me1hy1-2-pentanone
`3—Methoxypmpion1tn'1e
`Mednxytdglyeol
`Mexhyi acetate
`Memyi aeelueoetaie
`Methyl acrylalc
`Mezhylnmyl alcohol
`Methyl amyi kemne
`Mefayl benzene
`a-Methylbenzylamine
`u-Methyfbemyl Celiosolvea’
`a-Methyibenzyidiraethylaxninc
`2-MeI.11y1—1,3—butad1ene, see Isoprene
`2—Methy11nI1ane
`2-Methyl-1-butane
`2—Met1zy1—2-butane
`3-MeI1:y1—1—butene
`N-Meflzyibulyianiine
`Methyl bury] kelone
`Methyl sec-hutyl kewne
`Methyl ten-b1ny1 kelone
`3-Metfiylbutyraldehyde
`Methyl Cu:-bito1“’
`'
`Methyl Carbimi aoetaaae
`Methyl Ce13oso1vc‘3
`Me1i1y1Ce1106o1ve acetate
`Methyi chlumfonn. see 1,1,1-
`Trichlomcmane
`4-Me1hy1cye1ohexy1mefl1y1a.m1ne
`Meihylcyclopeutane
`N-Methyldibutylamine
`N-Methyldiezlzmmlernine
`4—Melhy1-3,4-dihydropyran
`2,5—cm2'oMc1hy1enecyI:lohexylmelhy1nminc
`2,5-endoMe11:y1eaeeyc1ohcxane-1-methanol
`2,5-endaMe11:y1ene-3-cyclohexenyl acetate
`2.5-endoklethylenecyclohexyl acetate
`Methylene dichioride, see Dichloramethane
`N-Mefluylethanoiamine
`Methy1e11:y1Ca11a1to1‘9
`
`Mfg moi"
`117.2
`142.3
`132.3
`129.2
`93.2
`70.1
`86.]
`81.1
`32.0
`84.1
`104.2
`146.2
`102.1
`2112.3
`130.2
`85.1
`164.2
`74.1
`116.1
`86.1
`102.2
`114.2
`136.2
`121.2
`166.2
`149.2
`72.2
`70.1
`70. 1
`70.1
`37.2
`100.2
`100.2
`100.2
`86.1
`120.2
`162.2
`76.1
`118.1
`
`pig car’
`0.868
`1.056
`0.939
`0.909
`0.854
`0.841
`1.009
`0.829
`0.736
`0.826
`0.917
`0.949
`0.921
`0.929
`0.903
`0.934
`1.043
`0.927
`1 .071
`0.950
`0.1103
`0.811
`1.081
`0.948
`1.034
`0.899
`0.614
`0.645
`0.657
`0.621
`11.723
`0.806
`0.008
`0.801
`0.795
`1.015
`1.034
`0.960
`0.999
`
`8,,
`13.5
`15.2
`15.4
`16.4
`14.7
`12.5
`17.0
`13.9
`11.6
`14.4
`14.1
`14.3
`13.7
`14.9
`13.4
`13.7
`13.4
`13.3
`13.6
`13.2
`13.1
`15.1
`15.9
`16.1
`13.7
`15.9
`13.8
`13.6
`14.2
`12.7
`14.2
`14.1
`14.1
`14.1
`13.6
`13.4
`14.6
`13.0
`14.7
`
`fifMPa"‘
`8,
`9.0
`0.0
`7.9
`7. 1
`9.6
`10.7
`13.0
`11.5
`13.0
`8-0
`3.3
`8.6
`9.9
`7.3
`3.8
`12.0
`9.4
`9.5
`12.2
`10.2
`7.6
`7.6
`11.5
`I I .1
`9.5
`7.3
`0.0
`4.1
`4. 1
`3.8
`6.7
`7.9
`8.0
`8.2
`8.5
`9.6
`9.6
`10.0
`9.11
`
`0.,
`12.8
`0.0
`0.0
`0.0
`6.6
`8.8
`16.2
`10.5
`24.0
`3.2
`14.3
`7.5
`9.9
`5.3
`6.3
`14.5
`14.8
`10.4
`12.0
`9.4
`10.5
`7.2
`7.2
`5.0
`1 1.9
`0.0
`0.0
`3.7
`3.8
`3.7
`6.6
`7.1
`6.2
`4.1
`7.5
`15.8
`10.3
`17.4
`9.9
`
`5,
`20.7
`15.2
`17.3
`17.9
`18.3
`13.7
`26.8
`20.9
`29.7
`13.4
`22.0
`18.3
`19.6
`17.4
`17.2
`23.3
`22.0
`19.4
`21.8
`19.2
`18.4
`18.4
`20.8
`20.4
`20.5
`17.5
`13.11
`14.7
`15.2
`13.7
`17.0
`17.7
`17.4
`16.8
`17.7
`22.13
`20.3
`23.9
`20.3
`
`127.2
`. 84.2
`143.3
`1 19.2
`98.2
`125.2
`14-0.3
`152.2
`154.2
`75. 1
`148.2
`
`0.888
`0.743
`0.755
`1.036
`0.890
`0.936
`0.986
`1.045
`1.022
`0.936
`0.913
`
`16.2
`15.7
`15.2
`12.8
`15.5
`16.5
`16.4
`16.0
`16.7
`14.1
`14.5
`
`8.0
`3.5
`3.2
`1 1.0
`7.9
`8.2
`9.0
`9.2
`8.2
`1 1 .4
`7.6
`
`5.1
`0.0
`2.9
`211.1
`2.5
`6.1
`11.1
`5-4
`5.1
`20.0
`3.6
`
`18.8
`16.0
`15.8
`26.2
`17.5
`19.4
`21.8
`19.3
`19.3
`27.0
`18.5
`
`i
`
`I
`.
`|
`
`I
`1
`1
`
`MYLAN PHARMS. INC. EXHIBIT 1044 PAGE 106
`
`

`
`TABLE 18 (continued)
`Hoy’s Cohesion Parameters for Liquids (and Soiids as Subcouled Liquids) at 25°C
`
`31111351-1
`
`133
`
`Liquid
`
`M1‘; 1130!"
`
`pig cm"
`
`6,
`
`1115111111 11111111 511151
`1v1e111;.«1e111y1 1151555
`2—Me£i1yI—543thylpyridine
`2-Methyiheptanc
`3.1115011113551555
`4.1111:-.411;-111515111151:
`2-115111111-1-115155511.-1
`2-111551511-24151115115
`3-Mcthy3—2—I'1e;1tez10
`3.1451113-1-2-115515115
`4413501,-1-14-151115115
`S-Mclizyl-I-hepiene
`511.5-Meuayz-2415515113
`6-Methyl-I-hcpteI1e
`c:'s‘-6-M:lhyl—2—heptene
`Mcthyl 111-.p1y1 11515.15
`2—Mefl1y1hc11a.1'1c
`3-1.1501511151111115
`5—Med1yl-2-hexane!
`Methyi hexyl 1451555
`N-Methylhornopipaazine
`111511151 3-hydmxybutymte
`111511.311 1s54my1 11515115
`1115111311 11151151311 11515115
`Methyi 155537111115
`1145111311 1359:5111-.5311 115155.:
`1.451151 115510534 115151111
`1145114311 meshacryiaac
`l-Me1i1yl-2,5-end:m1etI1yIeuecyciul1exan.e-1-
`5051111111111
`1-Methy}napl1t!mi1:1'1e
`2.111511014155155
`3-1.1501;-111111111115
`4.3151115115511555
`5-Mediyinonsnc
`2-Methyiuctme
`3.114501311551555
`4.1115313115511111:
`2—Me!hyipenta.113!
`2.115131715551555
`3-Me£hy1penta111:
`2-1115111y1—1,3.pen1am-.0151
`2-M1:1h31‘£—l.5-pemancditul
`2—Methylpcm.a13oic 55111
`2—Mc:hyipe1:1tat113l
`2-Methyl-2-pensazlol
`221115111311-3-115111111151
`3-Mcz11y1pm1m51
`3-Met|'.1yl—2—pen2a.IIol
`3—Me1hyl—3—pe11ta11ol
`4—Methylpe1'1ta11ol
`2.1051110255515531
`2-Methyl-1-pcntcne
`2-01513y1-2—p551eue
`3—Me!l:yl-1-pe11l1-,0:
`
`50.1
`72.1
`121.2
`114.2
`1 14.2
`114.2
`112.2
`112.2
`1 12.2
`112.2
`112.2
`112.2
`112.2
`112.2
`112.2
`142.2
`100.2
`100.2
`115.2
`123.2
`114.2
`113.1
`114.2
`100.2
`57.1
`34.1
`35.1
`100.1
`125.2
`
`142.2
`142.3
`142.3
`142.3
`142.3
`123.3
`123.3
`123.3
`100.2
`35.2
`35.2
`113.2
`113.2
`115.2
`102.2
`102.2
`102.2
`102.2
`102.2
`102.2
`102.2
`93.2
`34.2
`34.2
`34.2
`
`0.592
`0.300
`0.915
`0.593
`0.700
`0.599
`0.715
`0.719
`0.705
`0.724
`0.712
`0.711
`0.713
`0.707
`0.713
`0.321
`0.573
`0.532
`0.303
`0.314
`0.922
`1.053
`0.307
`0.795
`0.951
`0.347
`0.793
`0.930
`0.993
`
`1.014
`0.723
`0.723
`0.727
`0.723
`0.703
`0.715
`0.715
`0.305
`0.543
`0.559
`0.959
`0.970
`0.913
`0.320
`0.311
`0.320
`0.319
`0.325
`0.324
`0.309
`0.351
`0.574
`0.530
`0.552
`
`13.0
`14.1
`17.7
`15.11
`15.1
`15.1
`14.9
`15.3
`14.4
`15.3
`14.5
`14.5
`15.2
`14.5
`15.1
`14.5
`14.3
`14.9
`14.9
`15.1
`15.3
`11.9
`14.9
`14.4
`11.2
`14.11
`14.5
`13.7
`14.5
`
`17.9
`15.5
`15.7
`15.7
`15.5
`15.4
`15.4
`15.4
`14.1
`14.4
`14.5
`13.0
`14.2
`15.5
`14.2
`13.3
`14.7
`14.3
`15.2
`11.4
`15.5
`14.3
`14.1
`14.4
`13.7
`
`B,
`
`5.7
`9.3
`7.7
`0.0
`0.0
`0.0
`3.5
`3.5
`3.4
`3.5
`3.5
`3.4
`3.2
`3.4
`3.2
`5.9
`0.0
`0.0
`7.5
`7.2
`3.9
`10.9
`7.7
`3.1
`12.2
`10.3
`3.3
`9.3
`7.5
`
`9.5
`0.0
`0.0
`0.0
`0.0
`0.0
`0.0
`0.0
`3.0
`0.0
`0.0
`10.9
`11.5
`3.9
`3.5
`9.2
`3.0
`3.5
`3.2
`3.7
`3.7
`9.5
`3.9
`3.3
`3.7
`
`B.
`
`5.2
`9.5
`2.5
`0.0
`0.0
`0.0
`0.0
`0.0
`1 .3
`0.0
`0.0
`2.0
`0.0
`2.2
`0.0
`4.5
`0.0
`0.0
`11.3
`5.3
`5.5
`14.5
`5.3
`5.9
`13.5
`7.1
`5.5
`5.1
`21.5
`
`0.0
`0.0
`0.0
`0.0
`0.0
`0.0
`0.0
`0.0
`7.1
`0.3
`0.0
`13.5
`20.5
`11.3
`12.5
`11.1
`12.1
`13.0
`12.5
`10.1
`13.4
`7.7
`3.2
`3.4
`2.9
`
`8,
`
`15.5
`19.3
`19.5
`15.0
`15.1
`15.1
`15.3
`15.7
`14.9
`15.7
`15.0
`15.0
`15.5
`15.2
`15.4
`15.3
`14.3
`14.9
`20.2
`13.0
`19.4
`21.3
`17.7
`17.5
`21.7
`13.3
`13.3
`17.9
`27.2
`
`20.3
`15.5
`15.7
`15.7
`15.5
`15.4
`15.4
`15.4
`17.7
`14.4
`14.5
`25.2
`27.5
`21.5
`20.3
`19.5
`20.5
`21.5
`21.4
`17.5
`22.3
`19.2
`14.9
`15.3
`14.5
`
`I
`
`'
`I
`
`'
`
`.
`.
`
`I
`;
`
`-
`'
`
`'
`
`'
`
`25°C
`
`3_
`
`20.7
`15.2
`17.3
`17.9
`
`131;
`13.7
`25.3
`20.9
`29.7
`13.4
`22.0
`13.3
`19.5
`17.4
`17.2
`23.3
`22.0
`19.4
`21.3
`19.2
`13.4
`13.4
`20.3
`20.4
`20.5
`17.5
`
`13.3
`14.?
`15.2
`13.7
`17.0
`17.7
`17.4
`15.3
`.7.7
`12.3
`10.3
`3.9
`0.3
`
`3.3
`5.0
`1.3
`1.2
`1.5
`1.4
`-3
`-.3
`=.3
`
`.0
`.5
`
`
`
`MYLAN PHARMS. INC. EXHIBIT 1044 PAGE 107
`
`

`
`134
`
`CRC Handbook ofS0Zub1'Ziry Parameters and Otker Cohesion Parameter: TABLE 18 (continued)
`
`Hoy’s Cohesion Parameters for Liquids (and Solids as Snbmoled Liquids} at 25°C
`
`liquid
`
`M/g E10!"
`
`pig 01.11"
`
`5,
`
`3:'MPa"‘
`B,
`
`8,
`
`8,
`
`'
`
`.0
`
`'
`
`I
`
`,
`
`4-Me1.|!1y!—]—pe110:nc
`c111-4-McflIyi—2-pcnmne
`trans-4-Ma111yl—2-pcntcne
`4-Methyl-2-pentyl aoemc
`4—MetbyI-2-peniyl butymtc
`2-Mcflzylpcntyl 6161166611411
`4-Me‘lhyl—2—pcmy1‘ Cellosoiw:
`N-M1:1hyIpipc.1'a7.i11e
`2-Mediylprapaxm, isohntane
`2—Mct11)'l.pmpen0, isobutylene
`M0113-1 I-pr0pe.nyIe1i'1cr
`M1-.Lhyl propionate
`Meazyl propy! 161666
`2—MeLhyI-2-propylpenimwl
`N-1\6e:11y1-2-pyn-6116666
`a-Mcthylslyrcne
`2-Memyi-1,2,3,6-rc1n1uydmbcnza10ehyde
`4-Mcthylmtmhydmpyran
`2-Melhylthioefllyi scrylaie
`2—Mct|1y!LhiapI1e11e
`3—Mell1ylt!1iophcne
`Menoethanolaxnine, 2—u.min0ethan01'
`Mo hmim. iscapropanolarraine
`Morpholine
`Niuobmzune
`11104361114116
`I—Nit10pr0p1me
`2—Nim3p1'opane
`Nonane
`1-Nmanol
`sec-Nananol
`I-Noaene
`Nonyrbemne
`' Nonyl c6116so1ve0
`I-Nonylynaphthalena
`Nonylphezwl
`Oclane
`I-Ocumoi
`2—OCtal}0I
`I-oczene
`213-2-£16163:
`mm—2—0c1cne
`£1’.-1-3-0010111:
`Irarzs-3-0010110
`60-4-oc:cne
`1rw1sL4-Octane
`Octylbenzcae
`1.4-omhmnc
`Pmtadecane
`trans-1.3-Pen1adic1'1c
`Fenlmc
`1,5-Pflltmledifll
`1-PGIIIHROL 1111131 4166661
`2-1=em.4n61, m-amyl alcohol
`
`34.2
`114.2
`114.2
`144.2
`172.3
`146.2
`146.2
`100.2
`53.1
`56.1
`72.1
`88.1
`36.1
`144.3
`99.1
`113.2
`124.2
`100.2
`146.2
`5111.2
`93.2
`61.1
`75.1
`37.1
`123.1
`75.1
`39.1
`119.1
`123.3
`144.3
`144.3
`126.2
`204.3
`133.3
`254.4
`220.4
`114.2
`130.2
`130.2
`112.2
`112.2
`112.2
`112.2
`112.2
`112.2
`112.2
`190.3
`104.2
`212.4
`63.1
`72.2
`104.2
`113.2
`33.2
`
`0.653
`0.664
`0.663
`0.1153
`0.349
`0.332
`0.374
`0.393
`0.550
`0.537
`0.771
`0.909
`0.301
`0.333
`1.020
`0.905
`0.942
`0.953
`1.060
`1.012
`1.015
`1.012
`0.956
`0.995
`1.190
`1.045
`0.996
`0.985
`0.713
`0.323
`0.319
`0.724
`0.351
`0.365
`0.932
`0.941
`0.693
`0.322
`0.317
`0.710
`0.719
`0.714
`0.716
`0.710
`0.716
`0.709
`0.351
`1.112
`0.764
`0.671
`0.621
`0.937
`0.311
`0.305
`
`13.6
`14.2
`14.4
`14.4
`14.1
`13.6
`13.4
`16.7
`12.5
`12.6
`14.7
`13.9
`14.6
`14.3
`16.5
`16.6
`15.4
`15.3
`14.4
`15.1
`15.2
`13.9
`13.9
`16.0
`17.6
`19.0
`13.1
`16.5
`15.6
`15.3
`13.9
`15.4
`16.0
`13.7
`17.4
`15.6
`15.4
`15.2
`14.1
`15.0
`15.1
`15.1
`15.1
`15.1
`15.1
`15.1
`16.7
`16.3
`16.3
`14.1
`14.4
`13.9
`14.3
`15.0
`
`3.7
`3.5
`3.3
`7.0
`6.2
`7.2
`7.3
`9.0
`0.0
`4.2
`7.3
`8.8
`3.11
`7.3
`10.4
`11.5
`9.5
`6.3
`11.5
`12.1
`12.1
`13.8
`12.3
`11.4
`14.0
`13.0
`1 1.2
`10.4
`0.0
`7.3
`6.6
`3.4
`6.3
`6.4
`6.6
`6.7
`0.0
`7.7
`6.9
`3.5
`3.2
`3.0
`3.2
`3.0
`3. 2
`3.0
`5.4
`12.3
`0.0
`5.3
`0.0
`12.2
`9.1
`11.5
`
`3.0
`0.0
`0.0
`3.0
`3.6
`1 1 .4
`10.6
`5.2
`0.0
`3.0
`7.3
`8.9
`7.0
`10.2
`13.5
`0.0
`6.5
`0.0
`7.9
`2.6
`1.3
`25.9
`20.1
`10.1
`0.0
`0.0
`0.0
`6.6
`0.0
`12.0
`10.3
`0.0
`0.0
`9.2
`0.0
`9.1
`0.0
`12.4
`10.9
`2.3
`0.0
`0.0
`0.0
`0.0
`0.0
`0.0
`0.0
`5.2
`0.0
`4.3
`0.0
`22 .3
`14.7
`13.7
`
`14.4
`14.6
`14.7
`16.3
`15.11
`19.2
`13.6
`19.6
`12.5
`13.6
`13.2
`13.7
`13.4
`19.0
`23.7
`13.6
`19.2
`17.0
`20.1
`19.5
`19.5
`31.8
`27.3
`22.1
`22.5
`23.0
`21.3
`20.6
`15.6
`20.7
`13.5
`15.3
`17.4
`17.7
`111.6
`19.3
`15.4
`21.1
`19.1
`15.5
`15.5
`15.4
`15.5
`15.4
`15.4
`15.4
`17.5
`21.5
`16.3
`15.3
`14.4
`29.4
`22.7
`22.0
`
`
`
`MYLAN PHARMS. INC. EXHIBIT 1044 PAGE 108
`
`

`
`
`
`135
`
`TABLE 18 (continued)
`Hoy’s Cohesion Parameters for Liquids (and Solids as Subcooled Liquids) at 25°C
` Sflhrll-‘am
`
`Liquid
`
`Mfg mo!“
`
`9:’: cm"
`
`at
`
`8|
`
`51:
`
`8:
`
`3—Pm1tanol
`1—Penten-c
`cit-2-Pcntene
`trans-2-Pentene
`Pentyl acetate
`Pcnlylcyciohexsmc
`Pcrchlomethyiene. tctracluiumahylene
`Phenoxypropylenl: oxide
`Phcnyl Camila!‘
`Pheny! Ccllosoh-e‘
`Phenyl Cellosc-1ve"' aceiate
`N-Phcliyleiilanolamine
`Plmcnylhydmzine
`N-Phenylpipetazine
`Picoline
`Pinamlyi alcohol
`4:r—P111£nB
`Pipcridine
`Pivaldaelayclc
`Poiyglyoolamine H221M
`Propunah pmpionaldehydc
`
`2—Px-opanol, isoplupmml
`Propasofl‘ Solvent B. humxypropauol
`Pmpasolw Solvent DM
`Pmpssolfi Solvent M
`Propas01° Solvenl P, propmcypropanol
`Pmpionic acid
`Propionic rmllydridc
`Pzopinnitrile
`Pmpyl acetate
`Propyiamim-.
`Pmpylbcrlzene
`Prapyl Caxbitolfl
`Prupyl chloride. sec chlumpmpane
`Pmpylcyclohexalie
`Prepylcydopcmane
`Pmpylenc chlorohylirin
`Propylene diamine
`1’mpy1¢:m-. dichloride. soc 1,3—dic11loropro-
`Pam
`Pmpylane giycol, I,2—propanedio1
`Propylene oxide, methylnxirane
`4-Propylhcpume
`2-Propflhcplanoi
`m-Propyllolrucne
`o—Propy1to111en¢
`
`88.2
`70.1
`70.1
`70.]
`130.2
`154.3
`165.9
`150.2
`1821.2
`138.2
`180.2
`137.2
`108.1
`162.2
`93.1
`102.2
`136.2
`85.2
`86.1
`221.3
`58.1
`4-4.]
`76.1
`60.1
`60.1
`132.2
`148.2
`90.1
`118.2
`74.1
`130.1
`55.1
`102.1
`59.1
`120.2
`148.2
`
`126.2
`112.2
`94.5
`74.1
`
`76. I
`58.1
`142.3
`158.3
`134.2
`134.2
`134.2
`79.1
`104.2
`120.2
`154.2
`
`0.816
`0.635
`0.649
`0.642
`0.869
`0.799
`1 .611
`1.104
`1. 109
`1. 103
`1 .101
`1.091
`1.095
`1.064
`0.950
`0.815
`0.853
`0. 357
`(1.786
`1 JJ114
`0.791
`0.492
`1.050
`0.799
`0.781
`0.378
`0.955
`0.917
`0.880
`0.988
`1.005
`0.777
`0.881
`0.712
`0.856
`0.963
`
`0.788
`0.771
`1.106
`0.858
`
`1 .033
`0.823
`0.731
`0.1128
`0.855
`0. 869
`0.853
`0.973
`0.901
`1 .048
`0.927
`
`13.9
`1.3.9
`14.5
`14.1
`14.3
`16.0
`11.4
`17.6
`14.4
`13.7
`16.2
`15.2
`15.6
`18.1
`18.2
`14.2
`15.6
`16.2
`13.4
`13.9
`12.6
`11.8
`12.4
`14.1
`14.0
`13.2
`13.1
`12.9
`13.2
`15.3
`12.6
`12.6
`14.1
`13.9
`16.2
`13.1
`
`16.0
`16.0
`12.9
`13.5
`
`11.8
`13.6
`15.3
`14.5
`16.5
`16.7
`16.5
`17.6
`16.8
`17.5
`13.9
`
`8.3
`4.1
`3.8
`3.4
`'13
`2.3
`15.2
`11.8
`10.4
`10.4
`11.}
`11.9
`14.9
`11.4
`7.8
`8.0
`4.3
`8.7
`21.5
`9.2
`9.7
`0.0
`14.1
`10.5
`9.8
`7.5
`8.6
`9.2
`8.0
`11.2
`11 .4
`1.1.5
`3.1
`9.3
`6.9
`8.4
`
`2.5
`3.1.
`11.6
`12.8
`
`13.3
`8.2
`0.0
`6.9
`6.3
`6.5
`6.2
`10.1
`9.]
`11.4
`7.9
`
`13.0
`0.0
`0.0
`3.6
`5.7
`0.0
`0.0
`7.6
`14.3
`16.0
`8.8
`17.0
`13.7
`3.2
`6.8
`10.6
`0.0
`5.8
`5.5
`10-8
`11.0
`0.0
`27.1
`17.7
`16.0
`11.5
`12.2
`14.2
`12.1
`17.1
`10.4
`13-8
`7.8
`7.2
`0.11
`13.2
`
`0.0
`0.0
`16.0
`12.8
`
`25.0
`10.4
`0.0
`10.6
`0.0
`0.0
`0.0
`7.7
`0.0
`5.1
`10.2
`
`20.8
`14.5
`15.0
`14.9
`17.1
`16.1
`19.0
`22.5
`22.9
`23.5
`21.5
`25.7
`25.5
`21.6
`20.9
`19.5
`16.2
`19.3
`16.8
`19.8
`19.3
`11.8
`33.0
`24.9
`23.4
`19.0
`19.8
`21.3
`19.5
`25.5
`19.9
`22.0
`18.0
`18.2
`17.6
`20.4
`
`16.2
`16.3
`23.6
`22.6
`
`30.7
`111.9
`15.3
`19.2
`17.7
`17.9
`17.6
`21.7
`19.1
`21.5
`19.0
`
`——._.v--—-..-..._T
`
`4---5--.-pu.—.._-_.,.-=,.=._-
`
`
`
`MYLAN PHARMS. INC. EXHIBIT 1044 PAGE 109
`
`

`
`136
`
`CRC Handbook of Soiubiiiajr Parameters and Other Cohesion Parameters
`
`TABLE 13 (continued)
`Hoy’s Cohesion Parameters for Liquids {and Solids as Subcooied Liquids) at 25°C
`
`l
`
`.
`
`-
`
`.j
`--
`
`Liquid
`
`Wg moi“
`
`pig can‘!
`
`5,
`
`5,
`
`8,
`
`8,
`
` 8/MPH‘
`
`
`
`‘
`
`v
`
`-
`
`,
`_
`-
`
`,
`
`,
`
`,
`
`_
`
`'
`
`Te-tradecane.
`1.1,3.3-Tekaethaxypznpane
`1,2,3,6-Tetrahydmbenzsldehyde
`1.2,3,6-’1'e:.1'ahydmbenz0ic acid
`1,2.3,6—Tetrn11ydrobenzm3iui1e.-
`Tctrailydrofuran
`1,2,3.4—Ten'nl1)rdmna.ph1ha.lene
`'1‘en'abydropyran—2—m:z1;a.nnI
`1,1,3,5-Teuanxethoxyhexanc
`2,2,3,3-Tetrsmcrhylbutane
`N.N,N,N-Ten'amethy1—1,3—butanediam?nc
`N,N.N.N-Tetrmnelhyl-1,2—e1.hy1enedimninc
`2,2.3.3—Tct.rame1hy1penIanc
`N,N,N.N—'1‘au'aJ11c£11y1-1,3-propanediamiae
`2'I‘11iabutane
`Tlmtcyclopcntzne, Ieuahydmthiophcne
`2-Thiapropane
`'1‘hiop.benc
`Toluene. mcthylhemnime
`To1ylenc diisocyamue
`N—{o-Tolyfleliaanoiainirhe
`'1‘zia.11y1aminc
`Tribmyianaine
`1.1.1-Tlichlomexhane, mclhyl chlomfonn
`1,1,2-Trichlomcdiane
`1,1 ,2-1'nk:11loraed'ay1erne
`Trichlurom-ethane
`1,2.3—T:1'clI1or9propanB
`2.2,3—Trich.1eraprapio:1a1dc11ydz
`Tridacama
`1 .1,3-Txiethoxy-4-elhyluctanc
`'1'I'ir:th}'1a.1:|1in:
`Triethylene glycol
`Trialhy-1c:wtetr&|n1'JIe
`Trigiycoil dichioride
`1,1,3—Triz:1elhoxybu£3nc
`1,2,3-Trimeihylbcnzcm:
`1.2,4—Tx'1met11y1beI22x*.ne
`1,3,5—T|im:Ihy1herxzen.e. mcsilyknc
`2,2,3-Tfimethylbximnn
`I, 1.2—Tri:nct1:|y1cyc1open1a:ne
`1,1 ,3-Trimothylcyclopemanc
`2.2,3—T:imel11y111::ptnne
`2.2.4-Txilnethyllaeptane
`2,2,5-Trimedayihepume
`2,2,6-'I‘rime0:y1heptane
`2,3,3-Trimcthylheptanc
`2,3,4—Trimet‘hylhI:p¥a:ze
`2.3.5-Tr1mel11ylhqJhl.nc
`2.3.6-Triinedxyiheptane
`2,4,4-TI'imHhy1hep1a[1e
`2,4,5-'1‘ri1net11y111ep£s.ne
`2,4,6-Tl'i.lII.I:Ih}'1be])1aEl.8
`2,5,5—Tri:ncI:11y11'u:p:an1:
`
`198.4
`220.3
`1 10.2
`126.2
`107.2
`72.1
`132.2
`116.2
`206.3
`114.2
`144.3
`116.2
`128.3
`130.2
`76.2
`88.2
`62.1
`84.1
`92.1
`174.2
`151.2
`137.2
`185.4
`133.4
`133.4
`131.4
`119.4
`147.4
`161.4
`184.4
`275.5
`101.2
`150.2
`146.2
`187.0
`148.2
`120.2
`120.2
`120.2
`100.2
`112.2
`112.2
`142. 3
`142.3
`142.3
`142.3
`142.3
`142.3
`142.3
`142.3
`142.3
`142.3
`142.3
`142.3
`
`0.758
`0.913
`0.966
`1.077
`0.951
`0.382
`0.964
`1.021
`0.952
`0.320
`0.797
`0.772
`0.746
`0.777
`0. 835
`0.992
`0.841
`1,057
`0.862
`1,212
`1.067
`0.795
`0.775
`1.218
`1.432
`1.455
`1.477
`[.384
`1.467
`0.751
`0.866
`0.723
`1.249
`0.976
`1.190
`0.916
`0.889
`0.870
`0.860
`0.685
`0.767
`0.742
`0.737
`0.722
`0.721
`0.714
`9.743
`0.746
`0.736
`0.729
`0.728
`0.736
`0.717
`0.73]
`
`16.6
`13.5
`15.6
`18.6
`15.4
`13.3
`17.8
`14.4
`13.7
`17.1
`15.2
`15.0
`15.2
`15.1
`14.6
`17.4
`14.2
`14.0
`16.4
`15.3
`14.3
`13.8
`15.1
`10.8
`13.9
`11.7
`11.0
`14.8
`I 1.0
`16.4
`14.0
`14.6
`15.0
`12.7
`15.3
`13.6
`17.3
`16.9
`16.7
`14.2
`15.1
`14.6
`15.2
`14.6
`14.7
`14.6
`15.3
`15.4
`1.5.0
`14.9
`14.8
`15.0
`14.5
`14.8
`
`0.0
`1.4
`10.3
`11.3
`11.5
`11.0
`7.8
`9.6
`7.7
`0.0
`4.7
`5.1
`0.0
`4.8
`3.7
`10.9
`9.6
`12.4
`8.0
`16.4
`10.9
`6.6
`2.8
`11.5
`12.9
`14.0
`13.7
`12.7
`14.6
`0.0
`5.6
`3.7
`12.2
`12.4
`10.5
`7.8
`7.3
`7.1
`7.0
`0.0
`3.0
`2.9
`0.0
`0.0
`0.0
`0.0
`0.0
`0.0
`0.0
`0.0
`0.0
`0.0
`0.0
`0.0
`
`0.0
`6.7
`7.6
`13.7
`10.0
`6.7
`0.0
`13.5
`7. 1
`0.0
`2 .0
`2.7
`0.0
`2.6
`5.7
`0.6
`6.7
`7.5
`3.6
`7.8
`15.0
`4.1
`4.0
`0.0
`7.0
`4.4
`6.3
`6.7
`8.0
`0.0
`4.8
`1.9
`21.8
`14.1
`9.6
`6.6
`0.0
`0.0
`0.0
`0.0
`0.0
`0.0
`0.0
`0.0
`0.0
`0.0
`0.0
`0.0
`0.0
`0.0
`0.0
`0.0
`0.0
`0.0
`
`16.6
`16.8
`20.1
`25.7
`21.7
`18.5
`19.4
`22.0
`17.3
`17.1
`16.0
`16.0
`15.2
`16.1
`17.9
`20.5
`18.4
`20.0
`18.3
`23.7
`23.4
`15.8
`15.9
`15.8
`20.2
`18.7
`13.7
`20.6
`20.0
`16.4
`15.9
`15.2
`29.1
`22.8
`20.9
`17.0
`18.7
`18.3
`18.1
`1.4.2
`15 .4
`14.9
`15.2
`14.6
`14.1
`14.6
`15.3
`15.4
`15.0
`14.9
`14.11
`15.0
`14.5
`14.8
`
`
`
`MYLAN PHARMS. INC. EXHIBIT 1044 PAGE 110
`
`

`
`
`
`TABLE 18 (continued)
`1-1oy’s Cohen Parameters for Liquids {and Solids as Subcooled Liquids) at 25°C
` 5!MPa”’
`
`137
`
`Liquid
`
`Mfg mu!“
`
`93563"
`
`5.
`
`3.3.4-Tfimelhylhepianc
`3,3,5—Tri[ne‘t11y1heptane
`3,4,4-Trimelhylllcptarie
`3,4,S—'1'1‘itne:hy]hcptane
`2,2,3-Trimdhylhexanc
`2,2,4-Trimctilylhexxne
`2,2,5-Tliniclhylhexauc
`2,3,3-'!‘rirneLhylhexane
`2,3,4-Trimeflaylhexanc
`2.3,5—Trimeth}*1hexanc
`2,4,4-Trimethylhsxmw
`3,3,4—Tr1:ne1hy1.11cxarIe
`2,6,3-'I‘rimethy1r4-ncrnanol
`2.2.3-'I‘rin1ethy1pemane
`2,2,4-Trimcthylpemaue, isooclane
`2,3,3—Tzin1efl1yIpenta.m-.
`2,3,4~'1'YiIne£