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Issue published January 1, 2000
`Volume 105, Issue 1, Pages 3-125
`
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` 1
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`OSI EXHIBIT 2007
`APOTEX V. OSI
`IPR2016-01284
`
`

`
`Previous Issue (/104/12) | Next Issue (/105/2)
`
`Go to section:
`Perspectives - 2 in issue
`Commentaries - 2 in issue
`Research Articles - 10 in issue
`Erratum
`
`15 total articles
`
`Perspectives
`
`Lessons learned from the development of an Abl tyrosine kinase inhibitor for chronic
`myelogenous leukemia (/articles/view/9083)
`Brian J. Druker, Nicholas B. Lydon (/articles/view/9083)
`Brian J. Druker, Nicholas B. Lydon
` Published January 1, 2000
`Citation Information: J Clin Invest. 2000;105(1) (http://www.jci.org/105/1):3-7. doi:10.1172/JCI9083
`(http://dx.doi.org/10.1172/JCI9083).
`View: Text (/articles/view/9083) | PDF (/articles/view/9083/pdf)
` (http://www.jci.org/articles/view/9083/figure/1)
`
`Anticancer drug targets: growth factors and growth factor signaling (/articles/view/9084)
`Jackson B. Gibbs (/articles/view/9084)
`Jackson B. Gibbs
` Published January 1, 2000
`Citation Information: J Clin Invest. 2000;105(1) (https://www.jci.org/105/1):9-13. doi:10.1172/JCI9084
`(http://dx.doi.org/10.1172/JCI9084).
`View: Text (/articles/view/9084) | PDF (/articles/view/9084/pdf)
`
`Commentaries
`
`Aquaporins and the respiratory system: advice for a lung investigator (/articles/view/9023)
`Landon S. King, Søren Nielsen, Peter Agre (/articles/view/9023)
`Landon S. King, Søren Nielsen, Peter Agre
` Published January 1, 2000
`Citation Information: J Clin Invest. 2000;105(1) (http://www.jci.org/105/1):15-16. doi:10.1172/JCI9023
`(http://dx.doi.org/10.1172/JCI9023).
`View: Text (/articles/view/9023) | PDF (/articles/view/9023/pdf)
`
`
` 2
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`

`
` (http://www.jci.org/articles/view/9023/figure/1)
`
`Circulating endothelial precursors: mystery, reality, and promise (/articles/view/8774)
`Shahin Rafii (/articles/view/8774)
`Shahin Rafii
` Published January 1, 2000
`Citation Information: J Clin Invest. 2000;105(1) (http://www.jci.org/105/1):17-19. doi:10.1172/JCI8774
`(http://dx.doi.org/10.1172/JCI8774).
`View: Text (/articles/view/8774) | PDF (/articles/view/8774/pdf)
`
` (http://www.jci.org/articles/view/8774/figure/1)
`
`Research Articles
`
`Elastase and matrix metalloproteinase inhibitors induce regression, and tenascin-C antisense
`prevents progression, of vascular disease (/articles/view/6539)
`Kyle Northcote Cowan, Peter Lloyd Jones, Marlene Rabinovitch (/articles/view/6539)
`Kyle Northcote Cowan, Peter Lloyd Jones, Marlene Rabinovitch
` Published January 1, 2000
`Citation Information: J Clin Invest. 2000;105(1) (https://www.jci.org/105/1):21-34. doi:10.1172/JCI6539
`(http://dx.doi.org/10.1172/JCI6539).
`View: Text (/articles/view/6539) | PDF (/articles/view/6539/pdf)
` (https://www.jci.org/articles/view/6539/figure/1)
`
`Targeting of the chemokine receptor CCR1 suppresses development of acute and chronic
`cardiac allograft rejection (/articles/view/8126)
`Wei Gao ... Craig J. Gerard, Wayne W. Hancock (/articles/view/8126)
`Wei Gao ... Craig J. Gerard, Wayne W. Hancock
` Published January 1, 2000
`Citation Information: J Clin Invest. 2000;105(1) (https://www.jci.org/105/1):35-44. doi:10.1172/JCI8126
`(http://dx.doi.org/10.1172/JCI8126).
`View: Text (/articles/view/8126) | PDF (/articles/view/8126/pdf)
` (https://www.jci.org/articles/view/8126/figure/1)
`
`+
`Liddle’s syndrome mutations disrupt cAMP-mediated translocation of the epithelial Na
`channel to the cell surface (/articles/view/7869)
`
`
` 3
`
`

`
`Peter M. Snyder (/articles/view/7869)
`Peter M. Snyder
` Published January 1, 2000
`Citation Information: J Clin Invest. 2000;105(1) (https://www.jci.org/105/1):45-53. doi:10.1172/JCI7869
`(http://dx.doi.org/10.1172/JCI7869).
`View: Text (/articles/view/7869) | PDF (/articles/view/7869/pdf)
`
` (https://www.jci.org/articles/view/7869/figure/1)
`
`In vivo expression of a new hepatitis B virus protein encoded by a spliced RNA
`(/articles/view/8098)
`Patrick Soussan ... Christian Brechot, Dina Kremsdorf (/articles/view/8098)
`Patrick Soussan ... Christian Brechot, Dina Kremsdorf
` Published January 1, 2000
`Citation Information: J Clin Invest. 2000;105(1) (https://www.jci.org/105/1):55-60. doi:10.1172/JCI8098
`(http://dx.doi.org/10.1172/JCI8098).
`View: Text (/articles/view/8098) | PDF (/articles/view/8098/pdf)
`
` (https://www.jci.org/articles/view/8098/figure/1)
`
`CD4 T helper cells engineered to produce latent TGF-β1 reverse allergen-induced airway
`+
`hyperreactivity and inflammation (/articles/view/7589)
`Gesine Hansen ... Rosemarie H. DeKruyff, Dale T. Umetsu (/articles/view/7589)
`Gesine Hansen ... Rosemarie H. DeKruyff, Dale T. Umetsu
` Published January 1, 2000
`Citation Information: J Clin Invest. 2000;105(1) (https://www.jci.org/105/1):61-70. doi:10.1172/JCI7589
`(http://dx.doi.org/10.1172/JCI7589).
`View: Text (/articles/view/7589) | PDF (/articles/view/7589/pdf)
` (https://www.jci.org/articles/view/7589/figure/1)
`
`Origins of circulating endothelial cells and endothelial outgrowth from blood
`(/articles/view/8071)
`Yi Lin, Daniel J. Weisdorf, Anna Solovey, Robert P. Hebbel (/articles/view/8071)
`Yi Lin, Daniel J. Weisdorf, Anna Solovey, Robert P. Hebbel
` Published January 1, 2000
`Citation Information: J Clin Invest. 2000;105(1) (https://www.jci.org/105/1):71-77. doi:10.1172/JCI8071
`(http://dx.doi.org/10.1172/JCI8071).
`
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` 4
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`

`
`View: Text (/articles/view/8071) | PDF (/articles/view/8071/pdf)
`
` (https://www.jci.org/articles/view/8071/figure/1)
`
`2+
`Salmonella typhimurium induces epithelial IL-8 expression via Ca -mediated activation of the
`NF-κB pathway (/articles/view/8066)
`Andrew T. Gewirtz ... James L. Madara, Andrew S. Neish (/articles/view/8066)
`Andrew T. Gewirtz ... James L. Madara, Andrew S. Neish
` Published January 1, 2000
`Citation Information: J Clin Invest. 2000;105(1) (https://www.jci.org/105/1):79-92. doi:10.1172/JCI8066
`(http://dx.doi.org/10.1172/JCI8066).
`View: Text (/articles/view/8066) | PDF (/articles/view/8066/pdf)
`
` (https://www.jci.org/articles/view/8066/figure/1)
`
`Lung fluid transport in aquaporin-5 knockout mice (/articles/view/8258)
`Tonghui Ma, Norimasa Fukuda, Yuanlin Song, Michael A. Matthay, A.S. Verkman (/articles/view/8258)
`Tonghui Ma, Norimasa Fukuda, Yuanlin Song, Michael A. Matthay, A.S. Verkman
` Published January 1, 2000
`Citation Information: J Clin Invest. 2000;105(1) (https://www.jci.org/105/1):93-100. doi:10.1172/JCI8258
`(http://dx.doi.org/10.1172/JCI8258).
`View: Text (/articles/view/8258) | PDF (/articles/view/8258/pdf)
`
` (https://www.jci.org/articles/view/8258/figure/1)
`
`Chemotaxis of primitive hematopoietic cells in response to stromal cell–derived factor-1
`(/articles/view/7954)
`Deog-Yeon Jo, Shahin Rafii, Tsuneyoshi Hamada, Malcolm A.S. Moore (/articles/view/7954)
`Deog-Yeon Jo, Shahin Rafii, Tsuneyoshi Hamada, Malcolm A.S. Moore
` Published January 1, 2000
`Citation Information: J Clin Invest. 2000;105(1) (https://www.jci.org/105/1):101-111. doi:10.1172/JCI7954
`(http://dx.doi.org/10.1172/JCI7954).
`View: Text (/articles/view/7954) | PDF (/articles/view/7954/pdf)
`
`
` 5
`
`

`
` (https://www.jci.org/articles/view/7954/figure/1)
`
`A critical role for neutrophil elastase in experimental bullous pemphigoid
`(/articles/view/3693)
`Zhi Liu ... Janet A. Fairley, Luis A. Diaz (/articles/view/3693)
`Zhi Liu ... Janet A. Fairley, Luis A. Diaz
` Published January 1, 2000
`Citation Information: J Clin Invest. 2000;105(1) (https://www.jci.org/105/1):113-123. doi:10.1172/JCI3693
`(http://dx.doi.org/10.1172/JCI3693).
`View: Text (/articles/view/3693) | PDF (/articles/view/3693/pdf)
`
` (https://www.jci.org/articles/view/3693/figure/1)
`
`Erratum
`
`Nephritogenic mAb 5-1-6 is directed at the extracellular domain of rat nephrin
`(/articles/view/7728E1)
`Peter S. Topham ... Fujio Shimizu, David J. Salant (/articles/view/7728E1)
`Peter S. Topham ... Fujio Shimizu, David J. Salant
` Published January 1, 2000
`Citation Information: J Clin Invest. 2000;105(1) (http://www.jci.org/105/1):125-125. doi:10.1172/JCI7728E1
`(http://dx.doi.org/10.1172/JCI7728E1).
`View: Text (/articles/view/7728E1) | PDF (/articles/view/7728E1/pdf) | Amended Article (/articles/view/7728)
`
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` 6

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