IN THE UNITED STATES DISTRICT COURT
`FOR THE DISTRICT OF DELAWARE
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`Civil Action No. 12-cv-434-LPS
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`ENZO LIFE SCIENCES, INC.,
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`Plaintiff,
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`v.
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`AGILENT TECHNOLOGIES, INC.,
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`Defendant.
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`PLAINTIFF’S SUPPLEMENTAL INFRINGEMENT CHARTS
`FOR AGILENT TECHNOLOGIES
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`Pursuant to the Court’s Scheduling Order, Plaintiff Enzo Life Sciences, Inc. ("Plaintiff")
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`hereby provides its Supplemental Infringement Charts to Defendant Agilent Technologies, Inc.
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`("Agilent").
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`Plaintiff contends that Agilent, either alone or in conjunction with others, has directly
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`infringed and continues to directly infringe, literally and/or under the doctrine of equivalents, one
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`or more claims of U.S. Patent No. 7,064,197 (“the ’197 patent”) (the “Patent-in-Suit”) by
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`making, using, offering to sell, selling, and/or importing in or into the United States certain
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`nucleic acid array products, including without limitation:
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`a) ChIP-on-chip Microarrays, including without limitation Human ENCODE ChIP-on-chip
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`Microarray; Human Promoter Microarrays, including SurePrint G3 Human Promoter
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`Microarray Kit, 1x1M, SurePrint G3 Human Promoter Microarray 1x1M, SurePrint G3
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`Human Promoter Microarray Kit, 2x400K, SurePrint G3 Human Promoter Microarray
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`2x400K, Human Promoter Microarray Kit, 2-Design Set, 1x244K, Human Promoter
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`Microarray Set, 2-Design, 1x244; Model Organism ChIP-on-chip Microarrays, including
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`
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`1
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`Exhibit 2033 Page 1
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`Enzo Exhibit 2033
`Hologic, Inc. v. Enzo Life Sciences, Inc.
`Case IPR2016-00820
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`

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`Arabidopsis Genome Microarray, 2-Design Set, 1x244K, C. elegans Genome Microarray
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`Kit, 2-Design Set, 1x244K, Drosophila Genome Microarray Kit, 2-Design Set, 1x244K,
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`S. pombe Genome Microarray 4x44K, Yeast Genome Microarray Kit 1x244K, Yeast
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`Genome Microarray 1x244K, Yeast Genome Microarray Kit 4x44k, Yeast Genome
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`Microarray 4x44K, Zebrafish Promoter Microarray, 2-Design Set, 1x244K; Mouse
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`Promoter Microarrays, including SurePrint G3 Mouse Promoter Microarray Kit, 1x1M,
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`SurePrint G3 Mouse Promoter Microarray, 1x1M, SurePrint G3 Mouse Promoter
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`Microarray Kit, 2x400K, SurePrint G3 Mouse Promoter Microarray, 2x400K, Mouse
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`Promoter Microarray Kit, 2-Design Set, 1x244K, Mouse Promoter Microarray Set, 2-
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`Design, 1x244K, Oligo aCGH/ChIP-on-chip Hybridization Kit, Oligo aCGH/ChIP-on-
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`chip Hybridization Kit Large Volumes, and all other ChIP-on-chip Microarrays
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`(collectively, “ChIP-on-chip Products”),
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`b) CGH Microarrays, including without limitation, Human Genome CGH Microarrays,
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`including SurePrint G3 Human CGH Microarray Kit, 1x1M, SurePrint G3 Human CGH
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`Microarray, 1x1M, SurePrint G3 Human CGH Bundle, 1x1M, SurePrint G3 Human
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`CGH Microarray Kit, 2x400K, SurePrint G3 Human CGH Microarray, 2x400K,
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`SurePrint G3 Human CGH Bundle, 2x400K, SurePrint G3 Human CGH Microarray Kit,
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`4x180K, SurePrint G3 Human CGH Microarray, 4x180K, SurePrint G3 Human CGH
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`Bundle, 4x180K, SurePrint G3 Human CGH Microarray Kit, 8x60K, SurePrint G3
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`Human CGH Microarray, 8x60K, SurePrint G3 Human CGH Bundle 8x60K, Human
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`Genome CGH Microarray Kit 244A, Human Genome CGH Microarray 244A, Human
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`Genome CGH Microarray 244A Supplemental, Human Genome CGH Microarray Kit
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`105A, Human Genome CGH Microarray 105A, Human Genome CGH Microarray Kit,
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`2
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`Exhibit 2033 Page 2
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`

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`4x44K, Human Genome CGH Microarray, 4x44K, SurePrint G3 Unrestricted CGH ISCA
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`v2, 4x180K, Unrestricted HD-CGH Microarray ISCA v2, 2x105K, SurePrint G3
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`Unrestricted CGH ISCA v2, 8x60K, Unrestricted HD-CGH Microarray ISCA v2, 4x44k,
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`SurePrint G3 CGH ISCA v2 Microarray Kit, 8x60K; Model Organism CGH Microarrays,
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`including SurePrint G3 Bovine CGH Microarray, 4x180K, SurePrint G3 Canine CGH
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`Microarray, 4x180K, Chicken Genome CGH Microarray, 1x244K, SurePrint G3
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`Chimpanzee CGH Microarray, 4x180K; SurePrint G3 Rice CGH Microarray, 4x180K,
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`SurePrint G3 Rhesus Macaque Genome CGH Microarray, 4x180K; Mouse Genome
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`CGH Microarrays, including NOSdetect Assay Kit, SurePrint G3 Mouse CGH
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`Microarray Kit, 1x1M, SurePrint G3 Mouse CGH Microarray, 1x1M, SurePrint G3
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`Mouse CGH Microarray Kit, 4x180K, SurePrint G3 Mouse CGH Microarray, 4x180K,
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`Mouse Genome CGH Microarray Kit 244A, Mouse Genome CGH Microarray 244A,
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`Mouse Genome CGH Microarray Kit 105A, Mouse Genome CGH Microarray 105A; Rat
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`Genome CGH Microarrays, including SurePrint G3 Rat CGH Microarray Kit, 1x1M,
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`SurePrint G3 Rat CGH Microarray, 1x1M, SurePrint G3 Rat CGH Microarray Kit,
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`4x180K, SurePrint G3 Rat CGH Microarray, 4x180K, Rat Genome CGH Microarray Kit
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`244A, Rat Genome CGH Microarray 244A, Rat Genome CGH Microarray Kit 105A, Rat
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`Genome CGH Microarray 105A; Custom CGH Microarrays, including Custom HD-CGH
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`Microarray, 1x244K, Custom HD-CGH Microarray, 2x105K, Custom HD-CGH
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`Microarray, 4x44K, Custom HD-CGH Microarray, 8x15K, SurePrint G3 Custom CGH
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`Microarray, 1x1M, SurePrint G3 Custom CGH Microarray, 2x400K, SurePrint G3
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`Custom CGH Microarray, 4x180K, SurePrint G3 Custom CGH Microarray, 8x60K,
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`Sureprint G3 Custom CGH OGT Microarray 4x180K, Sureprint G3 Custom CGH OGT
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`3
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`Exhibit 2033 Page 3
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`

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`Microarray - 8x60K, SurePrint G3 CGH Postnatal Research Microarray Kit 4x180K,
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`SurePrint G3 CGH Postnatal Research Microarray Kit, 8x60K, and all other CGH
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`Microarrays (collectively, “CGH Products”),
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`c) CGH+SNP Microarrays, including without limitation, Human Genome CGH+SNP
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`Microrrays, including SurePrint G3 Human Genome CGH+SNP Microarray Kit,
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`2x400K, SurePrint G3 Human Genome CGH+SNP Bundle, 2x400K, SurePrint G3
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`Human Genome CGH+SNP Microarray Kit, 4x180K, SurePrint G3 Cancer CGH+SNP
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`Bundle, 4x180K, SurePrint G3 Cancer CGH+SNP Microarray Kit, 4x180K, SurePrint G3
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`ISCA CGH+SNP Microarray Kit, 4x180K, SurePrint G3 ISCA CGH+SNP Bundle,
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`4x180K; Custom CGH+SNP Arrays, including SurePrint G3 Custom CGH+SNP 1x1M,
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`SurePrint G3 Custom CGH+SNP 2x400K, SurePrint G3 Custom CGH+SNP 4x180K,
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`SurePrint G3 Custom CGH+SNP 8x60K, SurePrint G3 CGH+SNP Postnatal Research
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`Microarray Kit, and all other CGH+SNP Microarrays (collectively, “CGH+SNP
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`Products”),
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`d) CNV Microarrays, including without limitation, Human CNV Microarrays, including
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`SurePrint G3 Human High Resolution Microarray Kit, 1x1M, SurePrint G3 Human High
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`Resolution Microarray, 1x1M, SurePrint G3 Human CNV Microarray Kit, 2x400K,
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`SurePrint G3 Human CNV Microarray, 2x400K, Human Genome CNV Microarray Set,
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`Slide 1, 1x244K, Human Genome CNV Microarray Set, Slide 2, 1x244K, Human CNV
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`Association Microarray Kit, 2x105K, SurePrint G3 Human CNV Microarray, 2x105K,
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`and all other CNV Microarrays (collectively, “CNV Products”),
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`e) DNA Methylation Microarrays, including without limitation, Human CpG Island
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`Microarrays, including Human CpG Island Microarray Kit, 1x244K; Human DNA
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`4
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`Exhibit 2033 Page 4
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`Methylation Microarray, including Human DNA Methylation Microarray; Mouse CpG
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`Island Microarrays, including Mouse CpG Island Microarray, 2x105K; Custom DNA
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`Methylation Microarrays, including SurePrint G3 ChIP-on-chip/DNA Methylation,
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`1x1M, Custom SurePrint G3 ChIP-on-chip/DNA Methylation, 2x400K, Custom
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`SurePrint G3 ChIP-on-chip/DNA Methylation, 4x180K, Custom SurePrint G3 ChIP-on-
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`chip/DNA Methylation, 8x60K, Custom ChIP-on-chip/DNA Methylation, 1x244K,
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`Custom ChIP-on-chip/DNA Methylation, 2x105K, Custom ChIP-on-chip/DNA
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`Methylation, 4x44K, Custom ChIP-on-chip/DNA Methylation, 8x15K, and all other
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`DNA Methylation Microarrays (collectively, “DNA Methylation Products”)
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`f) Gene Expression Microarrays, including without limitation, Human Exon Microarrays,
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`including SurePrint G3 Human Exon 2x400K Microarray Kit, SurePrint G3 Human Exon
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`2x400K Microarray, SurePrint G3 Human Exon 4x180K Microarray Kit, SurePrint G3
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`Human Exon 4x180K Microarray; Human Gene Expression Microarrays, including
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`SurePrint G3 Human Gene Expression 8x60K v2 Microarray Kit, SurePrint G3 Human
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`Gene Expression 8x60K v2 Microarray, SurePrint G3 Human GE 8x60K Microarray Kit,
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`SurePrint G3 Human GE 8x60K Microarray, Human GE 4x44K v2 Microarray Kit,
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`Human GE 4x44K v2 Microarray, Whole Human Genome Microarray Kit, 4x44K,
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`Whole Human Genome Microarray Kit 4x44K; Model Organism Gene Expression
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`Microarrays, including Arabidopsis (V4) Gene Expression Microarray 4x44K, Barley
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`Gene Expression Microarray, 4x44K, Bovine (V2) Gene Expression Microarray, 4x44K,
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`Brassica Gene Expression Microarray, 4x44K, C. elegans (V2) Gene Expression
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`Microarray, 4x44K, Canine (V2) Gene Expression Microarray, 4x44K, Chicken (V2)
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`Gene Expression Microarray, 4x44K, Cotton Gene Expression Microarray, 4x44K,
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`5
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`Exhibit 2033 Page 5
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`

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`Drosophila Gene Expression Microarray, 4x44K, E. coli Gene Expression Microarray,
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`8x15K, Horse Gene Expression Microarray, 4x44K, Magnaporthe (V2) Gene Expression
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`Microarray, 4x44K, Medicago Gene Expression Microarray, 4x44K, Mosquito Gene
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`Expression Microarray, 4x44K, Porcine (V2) Gene Expression Microarray, 4x44K,
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`Rabbit Gene Expression Microarray, 4x44K, Rhesus Macaque (V2) Gene Expression
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`Microarray, 4x44K, Rice Gene Expression Microarray, 4x44K, Salmon Gene Expression
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`Microarray, 4x44K, Sheep Gene Expression Microarray, 8x15K, Tobacco Gene
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`Expression Microarray, 4x44K, Tomato Gene Expression Microarray, 4x44K, Wheat
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`Gene Expression Microarray, 4x44K, Xenopus (V2) Gene Expression Microarray,
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`4x44K, Yeast (V2) Gene Expression Microarray, 8x15K, Zebrafish (V3) Gene
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`Expression Microarray, 4x44K; Mouse Exon Microarrays, including SurePrint G3 Mouse
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`Exon 2x400K Microarray Kit, SurePrint G3 Mouse Exon 2x400K Microarray, SurePrint
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`G3 Mouse Exon 4x180K Microarray Kit, SurePrint G3 Mouse Exon 4x180K Microarray;
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`Mouse Gene Expression Microarrays, including SurePrint G3 Mouse GE 8x60K
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`Microarray Kit, SurePrint G3 Mouse GE 8x60K Microarray, Mouse GE 4x44K v2
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`Microarray Kit, Mouse GE 4x44K v2 Microarray, Whole Mouse Genome Microarray
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`Kit, 4x44K, Whole Mouse Genome Microarray, 4x44K, Mouse Development Microarray
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`Kit, 4x44K; Rat Exon Microarrays, including SurePrint G3 Rat Exon 2x400K Microarray
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`Kit, SurePrint G3 Rat Exon 2x400K Microarray, SurePrint G3 Rat Exon 4x180K
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`Microarray Kit, SurePrint G3 Rat Exon 4x180K Microarray; Rat Gene Expression
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`Microarrays, including SurePrint G3 Rat GE 8x60K Microarray Kit, SurePrint G3 Rat
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`GE 8x60K Microarray, Rat GE 4x4K v3 Microarray, Whole Rat Genome Microarray Kit,
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`4x44K, Rat Gene Expression Microarray; Custom Gene Expression Microarrays,
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`
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`6
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`Exhibit 2033 Page 6
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`

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`including Custom Gene Expression Microarray, 1x1M, Custom Gene Expression
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`Microarray, 2x400K, Custom Gene Expression Microarray, 4x180K, Custom Gene
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`Expression Microarray, 8x60K, Custom Gene Expression Microarray, 1x244K, Custom
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`Gene Expression Microarray, 2x105K, Custom Gene Expression Microarray, 4x44K,
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`Custom Gene Expression Microarray, 8x15K, and all other Gene Expression Microarrays
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`(collectively, “Gene Expression Products”), and
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`g) microRNA Microarrays, including without limitation, Human microRNA Microarrays,
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`including Human miRNA Microarray, Release 19.0, 8x60K, Human miRNA Microarray,
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`Release 18.0, 8x60K, Human miRNA Microarray Kit Release 16.0, 8x60K, Human
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`miRNA Microarray Release 16.0, 8x60K, Human miRNA Microarray Release 14.0,
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`8x15K, Human miRNA Microarray Kit (V3), 8x15K, Human miRNA Microarray (V3),
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`8x15K, Human miRNA Microarray (V2), Kit 8x15K, Human miRNA Microarray (V2),
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`8x15K, Human miRNA Microarray (V1) Kit, 8x15K, Human miRNA Microarray (V1),
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`8x15K; Mouse microRNA Microarrays, including Mouse miRNA Microarray Release
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`18.0, 8x60K, Mouse miRNA Microarray Kit Release 17.0, 8x60K, Mouse miRNA
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`Microarray Release 17.0, 8x60K, Mouse miRNA Microarray Kit Release 16.0 8x60K,
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`Mouse miRNA Microarray Release 16.0 8x60K, Mouse miRNA Microarray Release 15.0
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`8x15K, Mouse miRNA Microarray Release 12.0 8x15K, Mouse miRNA Microarray Kit
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`(V2) 8x15K, Mouse miRNA Microarray Kit 8x15K, Mouse miRNA Microarray 8x15K;
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`Rat microRNA Microarrays, including Rat miRNA Microarray Kit Release 16.0, 8x15K,
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`Rat miRNA Microarray Release 16.0, 8x15K, Rat miRNA Microarray Kit V1, 8x15K,
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`Rat miRNA Microarray Release 15.0, 8x15K, Rat miRNA Microarray Slide V1, 8x15K,
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`miRNA Complete Labeling and Hyb Kit; Custom miRNA Microarrays, including
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`
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`7
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`Exhibit 2033 Page 7
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`

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`Custom miRNA Microarray, 8x60K, Custom miRNA Microarray, 8x15K, and all other
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`microRNA Microarrays (collectively, “microRNA Products”)
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`(collectively, the “Accused Products”). Plaintiff further contends that Agilent has actively
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`induced, and continues to induce, the infringement of one or more claims of the ’197 patent
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`under 35 U.S.C. § 271(b). At all relevant times, Agilent actively, knowingly, and intentionally
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`induced others, including without limitation Agilent’s customers to use, make, sell, offer for sale,
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`and/or import the Accused Products, in a way that Agilent knew or should have known infringes
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`one or more claims of the ’197 patent. Plaintiff further contends that Agilent’s infringement of
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`the’197 patent has been, and continues to be, willful.
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`Plaintiff’s infringement contentions are provided herein without the benefit of full
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`discovery. The claim charts attached herein as Exhibits A and B identify where each limitation
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`of the asserted claims of the ’197 patent is found within the Accused Products. Plaintiff
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`contends that each element of each asserted claim is literally present in the Accused Products
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`unless otherwise indicated. But to the extent that any claim element is found not to be literally
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`embodied in the accused instrumentalities, Plaintiff contends that the Accused Products embody
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`such claim elements under the doctrine of equivalents because there are no substantial
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`differences for each claim element, and the Accused Products perform substantially the same
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`function, in substantially the same way, to achieve substantially the same result. To date,
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`Agilent has not provided non-infringement contentions in this case. Plaintiff reserves the right to
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`supplement its infringement contentions, including doctrine of equivalents contentions, in
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`response to Agilent’s non-infringement contentions.
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`Where a claim element is implemented in the same or substantially the same way for
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`each product of an Accused Product family (e.g., SurePrint Labeled DNA Products), Plaintiff
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`8
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`Exhibit 2033 Page 8
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`

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`provides an exemplary illustration or description setting forth specifically where the limitation is
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`found in the Accused Products, without repeating the same illustration or description for each
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`version of each Accused Product in the family.
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`Plaintiff provides these infringement contentions before fulsome discovery and before the
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`Court’s claim construction ruling. Moreover, depositions are ongoing, and Plaintiff reserves the
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`right to supplement its contentions based on additional relevant information disclosed during
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`depositions and through other means of discovery. And to the extent that Plaintiff receives
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`relevant discovery from third parties, Plaintiff reserves the right to supplement its contentions
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`accordingly. Plaintiff’s infringement contentions are not an admission, adoption, or waiver of
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`any particular claim construction; Plaintiff reserves all rights with respect to claim construction.
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`These infringement charts are based upon information reasonably and presently available
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`to Plaintiff through publicly-available information and Agilent’s production of documents to
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`date. Plaintiff reserves the right, consistent with its obligations under the Federal Rules of Civil
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`Procedure, the Local Rules, the Court’s Scheduling Order, and the Default Standard for
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`Discovery, including Discovery of Electronically Stored Information, to modify, amend, retract,
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`and/or supplement the infringement charts made herein as additional evidence and information
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`becomes available or as otherwise appropriate, including the issuance of the Court’s claim
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`construction ruling.
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`Plaintiff identifies the following asserted claims of the Patent-in-Suit and accused
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`products, as further explained in Exhibits A and B.
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`
`Asserted Claims of the ’197 Patent
`1-22, 27-34, 38-40, 43, 44, 46, 47, 49, 51, 57-59, 61-
`63, 65, 68-70, 72-74, 78, 80-82, 84-88, 90, 96-98,
`100, 102, 105, 106, 108, 113, 115, 116, 118, 120,
`122-124, 127-129, 131, 132, 136, 140, 146-148,
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`
`
`Agilent – Accused Products
`SurePrint Labeled DNA Products
`(ChIP-on-chip Products, CGH
`Products, CGH+SNP Products, CNV
`Products, and DNA Methylation
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`
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`9
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`Exhibit 2033 Page 9
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`

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`Asserted Claims of the ’197 Patent
`191-194, 196, 197, 199, 204, 206, 212, 213, 218,
`220-222, 224, 226, 227, 230, 232, 234
`1-22, 27-34, 38-40, 43, 46, 47, 49, 51, 57-59, 61-65,
`68-70, 72-74, 78, 80, 81, 84-88, 90, 96-98, 100, 102,
`105, 106, 108, 113, 115, 116, 118, 120, 122, 124,
`127-129, 131, 132, 136, 140, 146-148, 192-194,
`197, 199, 204, 206, 212, 213, 218, 220-222, 224,
`226, 227, 230, 232, 234
`
`
`
`Agilent – Accused Products
`Products). See Ex. A.
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`SurePrint Labeled RNA Products
`(Gene Expression Products and
`microRNA Products). See Ex. B.
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`
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`
`
`
`
`/s/ Brian E. Farnan
`
`
`Brian E. Farnan (Bar No. 4089)
`Farnan LLP
`919 North Market Street
`12th Floor
`Wilmington, DE 19801
`(302) 777-0300
`(302) 777-0301
`bfarnan@farnanlaw.com
`
`John M. Desmarais (admitted pro hac vice)
`Michael P. Stadnick (admitted pro hac vice)
`Jordan N. Malz (admitted pro hac vice)
`Justin P.D. Wilcox (admitted pro hac vice)
`Peter C. Magic (admitted pro hac vice)
`Joseph C. Akalski (admitted pro hac vice)
`Jessica A. Martinez (admitted pro hac vice)
`Danielle A. Shultz (admitted pro hac vice)
`DESMARAIS LLP
`230 Park Avenue
`New York, NY 10169
`(212) 351-3400
`(212) 351-3401
`jdesmarais@desmaraisllp.com
`mstadnick@desmaraisllp.com
`jmalz@desmaraisllp.com
`jwilcox@desmaraisllp.com
`pmagic@desmaraisllp.com
`jakalski@desmaraisllp.com
`jmartinez@desmaraisllp.com
`
`
`
`
`
`DATED: September 30, 2014
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`
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`10
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`Exhibit 2033 Page 10
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`

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`
`
`dshultz@desmaraisllp.com
`Counsel for Plaintiff
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`11
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`Exhibit 2033 Page 11