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`The Francis A.
`Countway Library of Medicine
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`HARVARD LIBRARY / RESEARCH GUIDES / HARVARD MEDICAL SCHOOL - COUNTWAY LIBRARY OF MEDICINE
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`[HMS] EBM - EVIDENCE-BASED MEDICINE / THE EVIDENCE PYRAMID - FINDING RESOURCES
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`[HMS] EBM - Evidence-based Medicine
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`Tutorials on the EBM process, EBM based information resources
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`Table of Contents
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`Levels of Evidence
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`You can use the TRIP Database to search for EBM sources that extend from
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`individual studies (cohort studies, RCTs) to systematic reviews and guidelines.
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`Filtered Information Sources
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`Filtered resources summarize and appraise evidence from several studies and
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`included systematic reviews, critically appraised topics, evidence-based
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`guidelines and point of care references.
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`DynaMed
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`Point-of-care reference resource designed to provide doctors and medical
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`researchers with the best available evidence to support clinical decision-
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`making. All evidence is critically appraised.
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`http://guides.library.harvard.edu/hms/ebm
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`6/2/2016
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`Ex. 2044-0001
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`The Evidence Pyramid - Finding Resources - [HMS] EBM - Evidence-based Medicine - ...
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`The Cochrane Database of Systematic Reviews
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`Detailed, structured topic reviews of hundreds of articles. Teams of experts
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`complete comprehensive literature reviews, evaluate the literature, and present
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`summaries of the findings of the best studies. Published by the International
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`Cochrane Collaboration.
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`ACP Smart Medicine and AHFS DI
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`Evidence-based point-of-care reference. Gives evidence in bibliographic form
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`and makes it easy to identify supporting studies. AHFS DI is a point-of-care
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`drug reference. Includes comparative price infromation.
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`The ACP Journal Club
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`Summarizes best new evidence from 130+ clinical journals and identify studies
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`that are methodologically sound and clinically relevant. An enhanced abstract,
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`with conclusions clearly stated, and a commentary are provided for each
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`selected article. Published by the American College of Physicians-American
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`Society of Internal Medicine and part of the Annals of Internal Medicine.
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`EvidenceUpdates from the BMJ
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`Articles from over 120 clinical journals are rated for quality, clinical relevance
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`and interest by an international group of physicians. Includes a searchable
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`database of the best evidence from the medical literature and an email alerting
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`system. REGISTRATION IS REQUIRED in order to search, but the database is
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`free and users are not harrassed.
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`Wiki Journal Club
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`Founded by medical students at UVM, the Wiki Journal Club is a collaborative
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`effort to review major trials. Includes critical appraisals of major trials. Good
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`coverage of major health questions. If the trial you're interested in has a catchy
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`acronym for a name, it might be here.
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`PDQ (Physician Data Query)
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`From the NCI - summaries for patients and healthcare professionals on
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`diagnosis, staging and treatment of cancers. All summaries linke directly to
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`evidence through PubMed and they are updated frequently.
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`Systematic reviews in PubMed (MEDLINE)
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`Quickly find systematic reviews in PubMed using Systematic Review
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`publication limit or just append AND systematic[sb] to your search.
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`Unfiltered Information Sources
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`Use these tools to search for primary studies. Utilize filters to find study types
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`that provide best evidence; to narrow your results by patient age or gender,
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`date or language.
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`PubMed
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`To limit your PubMed search to the best evidence-producing studies: Click on
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`"clinical queries" (in the center column of the main screen). This specialized
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`search is intended for clinicians and has built-in search "filters." After
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`http://guides.library.harvard.edu/hms/ebm
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`6/2/2016
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`Ex. 2044-0002
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`The Evidence Pyramid - Finding Resources - [HMS] EBM - Evidence-based Medicine - ...
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`completing a topic search you can also use the LIMITS tab and choose "Types
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`of Articles" such as Meta-analysis, Randomized Controlled Trial, Practice
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`Guideline, etc.
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`EMBASE
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`Major European biomedical and pharmaceutical database. Search your drug or
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`disease topic in EMBASE. Then click on Edit and then LIMIT, then MORE
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`LIMITS. An Evidence Based Medicine Box will appear where you can choose
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`from Cochrane Review, Systematic Reivew, Controlled Clinical Trial, etc.
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`PsycINFO
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`Psychological publications (not psychiatry). To limit your search to the best
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`evidence-producing studies: scroll down the search page to the Methodology
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`box. There you will find selections such as Systematic Review, Meta-analysis,
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`and Treatment Outcome/Clinical Trial.
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`CINAHL
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`Patient care, including nursing and allied health. To limit your search to
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`evidence-based literature, scroll down the search page and either select
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`appropriate EBM type studies (systematic review, controlled trial, etc.) from the
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`Publication Type box OR in the Special Interest box select Evidence Based
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`Practice OR click Evidence-based Practice box on the left.
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`Materials for EBM Assignment
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`• EBM Video
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`• (cid:2) Class slides
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`• (cid:3) PubMed Tips
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`• (cid:3) Assignment worksheet
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`Last Updated: Nov 15, 2015 2:54 PM
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`URL: http://guides.library.harvard.edu/hms/ebm (cid:1) Print Page
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`Login to LibApps
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`Subjects: Medical Sciences Tags: clerkship, clinical practice, critical appraisal, evidence-based, guidelines, hms, how_to, primary
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`clinical experience, pyramid
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`http://guides.library.harvard.edu/hms/ebm
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`6/2/2016
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`Ex. 2044-0003