C
`
`F
`
`t
`
`a'1£%ig3fe§ 2009
`
`CT 20,650
`NJ 47,920
`DE 4,690
`MD 26,650
`DC 2,600
`
`I
`
`.
`
`I
`
`'
`
`1,479,350
`
`0
`
`B
`
`'5'!)
`I
`HI
`6,400 D
`
`Estimated number of new cancer cases for 2009, excluding basal and squamous cell skin cancers and in situ carcinomas except urinary bladder.
`Note: State estimates are offered as a rough guide and should be interpreted with caution. State estimates may not add to US total due to rounding,
`
`Arrl-:=.rir_an
`
`Special Section:
`Multiple Primary Cancers
`see page 24
`
`AVENTIS EXHIBIT 2047
`Mylan v. Aventis, IPR2016-00712
`
`

`
`
`
`Contents
`
`Cancer: Basic Facts ................................................................................................................................ ..
`
`1
`
`Age—adjusted Cancer Death Rates, Males by Site, US, 1930—2005* ______________________________________________________________________ .. 2
`Age-adjusted Cancer Death Rates, Females by Site, US, 1930-2005* _________________________________________________________________ __ 3
`Estimated New Cancer Cases and Deaths by Sex, US, 2009* ___________________________________________________________________________ ., 4
`Estimated New Cancer Cases for Selected Cancer Sites by State, US, 2009* __________________________________________________________ __ 5
`Estimated Cancer Deaths for Selected Cancer Sites by State, US, 2009* _____________________________________________________________ ._ 6
`Cancer Incidence Rates by Site and State, US, 2001—2005* _____________________________________________________________________________ __ 7
`Cancer Death Rates by Site and State, US, 200l—2005* ..................................................................................... .. 8
`
`Selected Cancers ................................................................................................................................... .. 9
`
`Leading Sites of New Cancer Cases and Deaths — 2009 Estimates* ____________________________________________________________________ __ 10
`Probability of Developing Invasive Cancers (%) Over Selected Age Intervals by Sex, US, 2003-2005* ________________________ __ 14
`Five—year Relative Survival Rates (%) by Stage at Diagnosis, l996—2004* ___________________________________________________________ __ 17
`Trends in 5-year Relative Survival Rates (%) by Race and Year of Diagnosis, US, 1975-2004* ___________________________________ ._ 18
`
`Special Section: Multiple Primary Cancers ______________________________________________________________________________________ __ 24
`
`Cancer Disparities __________________________________________________________________________________________________________________________ ,_ 42
`Cancer Incidence and Mortality Rates by Site, Race, and Ethnicity, US, 2001—2005* _______________________________________________ _, 43
`Cancer Death Rates by Educational Attainment, Race, and Sex, US, 2001* ___________ __
`Geographic Patterns in Colorectal Cancer Death Rates by State, US, 2001—2005* _______________________________________________ __ 45
`
`Tobacco Use ___________________________________________________________________________________________________________________________________ ,_ 47
`
`Annual Number of Cancer Deaths Attributable to Smoking, by Sex and Site, US, 2000-2004* ________________________________ ._ 48
`
`Nutrition and Physical Activity ______________________________________________________________________________________________________ .. 54
`
`Environmental Cancer Risks ............................................................................................................... .. 56
`
`The International Fight against Cancer __________________________________________________________________________________________ ,_ 58
`
`The American Cancer Society _________________________________________________________________________________________________________ ._ 59
`
`Sources of Statistics ___________________________________________________________________________________________________________________________ _. 65
`
`Factors That Influence Cancer Rates ___________________________________________________________________________________________________ __ 67
`
`Screening Guidelines for the Early Detection of Cancer in Average—risk Asymptomatic People* ________________________________ ., 68
`
`*Indicates a figure or table
`
`Cancer Facts & Figures 2009 is dedicated to Drs. Jeanne Calle
`and Carmen Rodriguez, outstanding leaders and scientists in
`the Epidemiology department at the American Cancer Society,
`both recently deceased. Carmen, a breast cancer survivor, died
`of a second primary cancer in November 2008. Jeanne died
`
`miss them as friends, mentors, and colleagues.
`
`.
`.
`.
`.
`.
`.
`,
`unexpectedly in February 2009, a short time after retiring from
`her position as vice president of’Epidemiology. Jeanne s and.
`Carmen's research and leadership made important contributions
`to understanding the causes and prevention of cancer. We dearly
`
`National Home Office: American Cancer Society Inc.
`250 Wl“lamS Street NW. Atlanta. GA 30303-1002
`(404) 3203333
`@2009. Ametifian Cancer 50Cl€iY,
`INC All rights reserved,
`including the right to reproduce this publication
`,
`_
`or portions thereof in any form.
`For written permission, a
`resst e Lega
`epartmerito
`dd
`h
`Id
`f
`the American Cancersodety 250 Williams Street, NW
`Aflantal GA 303034002‘
`
`Thispublication attempts to summarize current scientific information about cancer.
`Except when Specified, it does not represent the oflicialpolicy ofthe American Cancer Society.
`
`Suggested citation: American Cancer Society. Cancer Facts &FigureS 2009. Atlanta: American Cancer Society; 2009.
`
`

`
`Cancer: Basic Facts
`
`What Is Cancer?
`
`Cancer is a group of diseases characterized by uncon-
`trolled growth and spread of abnormal cells. Ifthe spread
`is not controlled, it can result in death. Cancer is caused
`
`by both external factors (tobacco, infectious organisms,
`chemicals, and radiation) and internal factors (inherited
`mutations, hormones, immune conditions, and mutations
`
`that occur from metabolism). These causal factors may
`act together or in sequence to initiate or promote carcino-
`genesis. Ten or more years often pass between exposure to
`external factors and detectable cancer. Cancer is treated
`
`with surgery, radiation, chemotherapy, hormone therapy,
`biological therapy, and targeted therapy.
`
`Can Cancer Be Prevented?
`
`All cancers caused by cigarette smoking and heavy use
`of alcohol could be prevented completely. The Ameri-
`can Cancer Society estimates that in 2009 about 169,000
`cancer deaths are expected to be caused by tobacco use.
`Scientific evidence suggests that about one-third of the
`562,340 cancer deaths expected to occur in 2009 will be
`related to overweight or obesity, physical inactivity, and
`poor nutrition and thus could also be prevented. Certain
`cancers are related to infectious agents, such as hepati-
`tis B virus (HBV), human papillomavirus (HPV), human
`immunodeficiency virus (HIV), Helicobacter pylori (H.
`pylori), and others, and could be prevented throughbehav-
`ioral changes, vaccines, or antibiotics. In addition, many
`of the more than 1 million skin cancers that are expected
`to be diagnosed in 2009 could be prevented by protection
`from the sun’s rays and avoiding indoor tanning.
`
`Regular screening examinations by a health care pro-
`fessional can result in the detection and removal of
`
`precancerous growths, as well as the diagnosis of cancers
`at an early stage, when they are most treatable. Cancers
`that can be prevented by removal of precancerous tissue
`include cancers of the cervix, colon, and rectum. Cancers
`that can be diagnosed early through screening include
`cancers of the breast, colon, rectum, cervix, prostate, oral
`cavity, and skin. For cancers of the breast, colon, rectum,
`and cervix, early detection has been proven to reduce
`mortality. A heightened awareness of breast changes
`or skin changes may also result in detection of these
`tumors at earlier stages. Cancers that can be prevented
`or detected earlier by screening account for at least half
`of all new cancer cases.
`
`Who Is at Risk of Developing Cancer?
`Anyone can develop cancer. Since the risk of being diag-
`nosed with cancer increases as individuals age, most
`cases occur in adults who are middle-aged or older. About
`77% of all cancers are diagnosed in persons 55 years and
`older. Cancer researchers use the word “risk” in different
`
`ways, most commonly expressing risk as lifetime risk or
`relative risk.
`
`Lifetime risk refers to the probability that an individual,
`over the course of a lifetime, will develop or die from can-
`cer. In the US, men have slightly less than a 1 in 2 lifetime
`risk of developing cancer; for women, the risk is a little
`more than 1 in 3.
`
`Relative risk is a measure of the strength of the relation-
`ship between risk factors and a particular cancer. It
`compares the risk of developing cancer in persons with a
`certain exposure or trait to the risk in persons who do not
`have this characteristic. For example, male smokers are
`about 23 times more likely to develop lung cancer than
`nonsmokers, so their relative risk is 23. Most relative risks
`are not this large. For example, women who have a first-
`degree relative (mother, sister, or daughter) with a history
`of breast cancer have about twice the risk of developing
`breast cancer compared to women who do not have this
`family history.
`
`All cancers involve the malfunction of genes that con-
`trol cell growth and division. About 5% of all cancers are
`strongly hereditary, in that an inherited genetic altera-
`tion confers a very high risk of developing one or more
`specific types of cancer. However, most cancers do not
`result from inherited genes but from damage to genes
`occurring during one’s lifetime. Genetic damage may
`result from internal factors, such as hormones or the
`metabolism of nutrients within cells, or external factors,
`
`such as tobacco, chemicals, and sunlight.
`
`How Many People Alive Today Have
`Ever Had Cancer?
`
`The National Cancer Institute estimates that approxi-
`mately 11.1 million Americans with a history of cancer
`were alive in January 2005. Some of these individuals
`were cancer-free, while others still had evidence ofcancer
`and may have been undergoing treatment.
`
`How Many New Cases Are Expected to
`Occur This Year?
`
`About 1,479,350 new cancer cases are expected to be diag-
`nosed in 2009. This estimate does not include carcinoma
`
`in situ (noninvasive cancer) of any site except urinary
`bladder, and does not include basal and squamous cell
`skin cancers. More than 1 million unreported cases of
`
`Cancer Facts & Figures 2009
`
`1
`
`

`
`basal and squamous cell skin cancers are expected to be
`diagnosed this year.
`
`How Many People Are Expected to Die
`of Cancer This Year?
`
`This year, about 562,340 Americans are expected to die of
`cancer, more than 1,500 people a day. Cancer is the second
`most common cause of death in the US, exceeded only by
`heart disease. In the US, cancer accounts for nearly 1 of
`every 4 deaths.
`
`What Percentage of People
`Survive Cancer?
`
`The 5-year relative survival rate for all cancers diagnosed
`between 1996-2004 is 66%, up from 50% in 1975-1977.
`(See page 18.) The improvement in survival reflects prog-
`ress in diagnosing certain cancers at an earlier stage
`and improvements in treatment. Survival statistics vary
`greatly by cancer type and stage at diagnosis. Relative
`survival compares survival among cancer patients to
`that of people not diagnosed with cancer who are of the
`same age, race, and sex. It represents the percentage of
`cancer patients who are alive after some designated time
`period (usually 5 years) relative to persons without can-
`
`cer. It does not distinguish between patients who have
`been cured and those who have relapsed or are still in
`treatment. While 5-year relative survival is useful in
`monitoring progress in the early detection and treatment
`of cancer, it does not represent the proportion of people
`who are cured permanently, since cancer deaths can
`occur beyond 5 years after diagnosis.
`
`Although relative survival for specific cancer types
`provides some indication about the average survival
`experience of cancer patients in a given population, it
`may or may not predict individual prognosis and should
`be interpreted with caution. First, 5-year relative survival
`rates are based on patients who were diagnosed from
`1996-2004 and do not reflect recent advances in detection
`and treatment. Second, factors that influence survival,
`such as treatment protocols, additional illnesses, and
`biological or behavioral differences of each individual,
`cannot be taken into account in the estimation of relative
`survival rates. For more information about survival rates,
`see Sources of Statistics on page 65.
`
`How Is Cancer Staged?
`Staging describes the extent or spread of the disease at
`the time of diagnosis. Proper staging is essential in deter-
`
`Age-adjusted Cancer Death Rates,* Males by Site, US, 1930-2005
`100
`
`Lung El |:m:InI:hus
`
`
`
`
`
`AmericanCancerSociety,SurveillanceandHealthPolicyResearch,2009
`
`
`
`
`
`
`
`C71C2
`
`-isO
`
`2|}
`
`Colon E rectum
`
`Pl'Ii.'r.'-‘I31:
`
`r:
`.90-‘
`.5!3
`8‘o.
`.9W
`
`E 3I
`
`n 3
`
`.
`3reA:
`
`1930
`
`1935
`
`1940
`
`1945
`
`1950
`
`1955
`
`1960
`
`1965
`
`1970
`
`1975
`
`1980
`
`‘I985
`
`1990
`
`1995
`
`2000
`
`2005
`
`*Per 100,000, age adjusted to the 2000 US standard population.
`Note: Due to changes in ICD coding, numerator information has changed over time. Rates for cancer of the liver, lung and bronchus, and colon and
`rectum are affected by these coding changes.
`Source: US Mortality Data, 1960 to 2005, US Mortality Volumes, 1930 to 1959, National Center for Health Statistics, Centers for Disease Control
`and Prevention, 2008,
`
`2 Cancer Facts & Figures 2009
`
`

`
`mining the choice of therapy and in assessing prognosis.
`A cancer’s stage is based on the primary tumors size
`and whether it has spread to other areas of the body. A
`number of different staging systems are used to classify
`tumors. The TNM staging system assesses tumors in
`three ways: extent of the primary tumor (T), absence or
`presence of regional lymph node involvement (N), and
`absence or presence of distant metastases (M). Once
`the T, N, and M are determined, a stage of I, II, III, or IV
`is assigned, with stage I being early and stage IV being
`advanced disease. A different system of summary staging
`(in situ, local, regional, and distant) is used for descriptive
`and statistical analysis of tumor registry data. If cancer
`cells are present only in the layer of cells where they devel-
`oped and have not spread, the stage is in situ. If cancer
`cells have penetrated the original layer of tissue, the can-
`cer is invasive. (For a description of the other summary
`stage categories, see Five-year Relative Survival Rates by
`Stage at Diagnosis, 1996-2004, page 17.) As the molecu-
`lar properties of cancer have become better understood,
`prognostic models have been developed for some cancer
`sites that incorporate biological markers and genetic fea-
`tures in addition to anatomical characteristics.
`
`What Are the Costs of Cancer?
`The National Institutes of Health estimates overall costs
`of cancer in 2008 at $228.1 billion: $93.2 billion for direct
`
`medical costs (total of all health expenditures); $18.8 bil-
`lion for indirect morbidity costs (cost of lost productivity
`due to illness); and $116.1 billion for indirect mortality
`costs (cost of lost productivity due to premature death).
`
`Lack ofhealth insurance and other barriers prevent many
`Americans from receiving optimal health care. According
`to early release estimates from the 2008 National Health
`Interview Survey, about 24% of Americans aged 18 to 64
`years and 13% of children had no health insurance cov-
`erage for at least part of the past year. More than 36% of
`adults who lack a high school diploma were uninsured in
`the past year, compared to 23% of high school graduates
`and 14% of those with more than a high school educa-
`tion. Lack of health insurance is not only a concern of the
`unemployed; almost one-quarter of employed individuals
`(aged 18 to 64 years) were uninsured sometime during
`the past year. For more information on the relationship
`between health insurance and cancer, please see Cancer
`Facts &Figures 2008 (5008.08), Special Section, available
`online at cancer.org.
`
`Age—adjusted Cancer Death Rates,* Females by Site, US, 1930-2005
`
`100
`
`am
`
`8”
`
`.§8K
`
`lL:
`E2
`%¥
`
`0'10
`
`4>o
`
`..i.,”g‘i;....;ihi..;
`
`
`
`Rateper100,000femalepopulation
`
`
`
`
`
`E E3
`
`.3
`
`E €
`
`E3:
`-Eu
`5
`
`1930
`
`1935
`
`1940
`
`1945
`
`1950
`
`1955
`
`1960
`
`1965
`
`1970
`
`1975
`
`1980
`
`1985
`
`1990
`
`1995
`
`2000
`
`2005
`
`*Per 100,000, age adjusted to the 2000 US standard population. ‘Uterus cancer death rates are for uterine cervix and uterine corpus combined.
`Note: Due to changes in ICD coding, numerator information has changed over time. Rates for cancer of the lung and bronchus, colon and rectum,
`and ovary are affected by these coding changes.
`Source: US Mortality Data, 1960 to 2005, US Mortality Volumes, 1930 to 1959, National Center for Health Statistics, Centers for Disease Control
`and Prevention, 2008.
`
`Cancer Facts & Figures 2009
`
`3
`
`

`
`Estimated New Cancer Cases and Deaths by Sex, US, 2009*
`Estimated New Cases
`
`Estimated Deaths
`
`All sites
`Oral cavity & pharynx
`Tongue
`Mouth
`Pharynx
`Other oral cavity
`Digestive system
`Esophagus
`Stomach
`Small intestine
`Colon’
`Rectum
`Anus, anal canal, & anorectum
`Liver & intrahepatic bile duct
`Gallbladder & other biliary
`Pancreas
`Other digestive organs
`Respiratory system
`Larynx
`Lung & bronchus
`Other respiratory organs
`Bones & joints
`Soft tissue (including heart)
`skin (excluding baseil &squamous)
`Melanoma
`Other non-epithelial skin
`Breast
`Genital system
`Uterine cervix
`Uterine corpus
`Ovary
`Vulva
`Vagina & other genital, female
`Prostate
`Testis
`Penis 81 other genital, male
`Urinary system
`Urinary bladder
`Kidney & renal pelvis
`Ureter 81 other urinary organs
`Eye & orbit
`Brain & other nervous system
`Endocrine system
`Thyroid
`Other endocrine
`
`Male
`_B_oth Sexes
`766,130
`1,479,350
`25,240
`35,720
`7,470
`10,530
`6,450
`10,750
`10,020
`12,610
`1,300
`1,830
`150,020
`275,720
`12,940
`16,470
`12,820
`21,130
`3,240
`6,230
`52,010
`106,100
`23,580
`40,870
`2,100
`5,290
`16,410
`22,620
`4,320
`9,760
`21,050
`42,470
`1,550
`4,780
`129,710
`236,990
`9,920
`12,290
`116,090
`219,440
`3,700
`5,260
`1,430
`' 2370
`5,780
`10,660
`74,610— _ ' 42,920
`68,720
`39,080
`5,890
`3,840
`194,280 ‘ --
`1,910 '
`282,690
`201,970
`11,270
`42,160
`21,550
`3,580
`2,160
`192,280
`8,400
`1,290
`131,010
`70,980
`57,760
`2,270
`2,3507
`—__ --
`22,070
`39,330
`37,200
`2,130
`
`192,280
`8,400
`1,290
`89,640
`52,810
`35,430
`1,400
`3,200
`12,010‘
`11,070 _ '
`10,000
`1,070
`
`Female
`713,220
`10,480
`3,060
`4,300
`2,590
`530
`125,700
`3,530
`8,310
`2,990
`54,090
`17,290
`3,190
`6,210
`5,440
`21,420
`3,230
`107,280
`2,370
`103,350
`1,560
`1,140
`4,880
`31,690
`29,640
`2,050
`492,370" '
`80,720
`11,270
`42,160
`21,550
`3,580
`2,160
`
`41,370
`18,170
`22,330
`870
`1,150
`' 10,060
`28,260
`27,200
`1,060
`
`Both Sexes
`562,340
`7,600
`1,910
`1,810
`2,230
`1,650
`135,830
`14,530
`10,620
`1,110
`49,920
`
`710
`18,160
`3,370
`35,240
`2,170
`163,790
`3,660
`159,390
`740
`1,470
`3,—820 H
`7,590
`8,650
`2,940
`40,610
`56,160
`4,070
`7,780
`14,600
`900
`770
`27,360
`380
`300
`28,100
`14,330
`12,980
`790
`
`Male _
`292,540
`5,240
`1,240
`1,110
`1,640
`1,250
`76,020
`11,490
`6,320
`580
`25,240
`
`260
`12,090
`1,250
`18,030
`760
`92,240
`2,900
`88,900
`440
`
`"
`28,040
`
`- Femalefl W
`269,800
`2,360
`670
`700
`590
`400
`59,810
`3,040
`4,300
`530
`24,680
`
`450
`6,070
`2,120
`17,210
`1,410
`71,550
`760
`70,490
`
`40,170
`28,120
`4,070
`7,780
`14,600
`900
`770
`
`’
`
`'5
`
`33,860
`40,630”
`74,490
`En71Bh~oTna'
`3,870
`4,640
`8,510
`Hodgkin lymphoma
`29,990
`35,990
`65,980
`Non-Hodgkin lymphoma
`8,900
`11,680
`20,580 "
`Myeloma
`19,160
`25,630
`44,790
`Leukemia
`2,410
`3,350
`5,760
`Acute lymphocytic leukemia
`6,290
`9,200
`15,490
`Chronic lymphocytic leukemia
`5,890
`6,920
`12,810
`Acute myeloid leukemia
`2,120
`2,930
`5,050
`Chronic myeloid leukemia
`2,450
`3,230
`5,680
`Other leukemia‘
`16,200
`15,290
`31,490 5'
`Other & unspecified primary sites’
`* Rounded to the nearest 10; estimated new cases exclude basal and squamous cell skin cancers and in situ carcinomas except urinary bladder. About 62,280 female
`carcinoma in situ of the breast and 53,120 melanoma in situ will be newly diagnosed in 2009. tEstimated deaths for colon and rectum cancers are combined.
`15 More deaths than cases suggests lack of specificity in recording underlying causes of death on death certificates.
`Source: Estimated new cases are based on 1995-2005 incidence rates from 41 states and the District of Columbia as reported by the North American Association
`of Central Cancer Registries (NAACCR), representing about 85% of the US population. Estimated deaths are based on data from US Mortality Data, 1969-2006,
`National Center for Health Statistics, Centers for Disease Control and Prevention, 2009.
`©2009, American Cancer Society, Inc., Surveillance and Health Policy Research
`
`4 Cancer Facts & Figures 2009
`
`

`
`Estimated New Cancer Cases for Selected Cancer Sites by State, US, 2009*
`Melanoma Non-
`Urinary
`of the Hodgkin
`Skin Lymphoma Prostate Bladder
`930
`950
`2,800
`960
`80
`110
`360
`120
`1,460
`1,250
`3,530
`1,460
`500
`680
`2,140
`610
`9,080
`7,140
`20,790
`6,870
`1,260
`920
`3,070
`940
`1,260
`920
`2,400
`1,120
`220
`190
`550
`220
`70
`90
`380
`90
`4,920
`4,640
`12,380
`5,490
`
`Lung &
`Female Uterine Colon & Uterine
`Breast
`Cervix
`Rectum Corpus Leukemia Bronchus
`2,970
`190
`2,480
`510
`590
`4,040
`370
`T
`250
`70
`70
`350
`3,470
`210
`2,680
`660
`810
`3,960
`1,820
`130
`1,540
`310
`420
`2,580
`21,740
`1,350
`14,680
`4,230
`4,570
`17,910
`2,840
`150
`1,860
`530
`720
`2,240
`2,790
`110
`1,950
`660
`540
`2,720
`600
`T
`440
`140
`120
`800
`340
`T
`260
`80
`50
`370
`12,650
`800
`10,420
`2,590
`3,180
`17,790
`
`State
`Alabama
`Alaska
`Arizona
`Arkansas
`California
`Colorado
`Connecticut
`Delaware
`Dist. of Columbia
`Florida
`
`All Sites
`24,090
`2,530
`27,600
`14,800
`152,170
`20,340
`20,650
`4,690
`2,600
`102,210
`
`Georgia
`Hawaii
`Idaho
`Illinois
`Indiana
`Iowa
`Kansas
`Kentucky
`Louisiana
`Maine
`
`39,080
`6,400
`6,800
`60,960
`31,320
`16,740
`13,080
`24,060
`22,170
`9,000
`
`5,370
`870
`810
`7,610
`3,710
`2,080
`1,790
`2,840
`2,700
`1,080
`
`340
`50
`T
`480
`220
`90
`90
`180
`190
`50
`
`3,750
`710
`630
`6,430
`3,260
`1,800
`1,290
`2,620
`2,330
`870
`
`930
`200
`170
`1,960
`970
`500
`400
`590
`430
`270
`
`1,080
`160
`250
`1,940
`930
`590
`380
`690
`660
`270
`
`6,150
`740
`820
`9,180
`5,360
`2,620
`2,110
`4,650
`3,650
`1,390
`
`2,040
`320
`380
`2,010
`1,170
`910
`610
`1,260
`630
`480
`
`1,560
`260
`330
`2,900
`1,420
`750
`600
`980
`960
`360
`
`5,210
`860
`1,170
`7,590
`3,250
`2,330
`1,970
`2,910
`3,160
`1,130
`
`1,400
`220
`340
`3,100
`1,550
`870
`620
`1,070
`910
`500
`
`3,580
`1,110
`1,120
`1,31 0
`4,060
`640
`840
`2,620
`190
`3,660
`26,650
`Maryland
`4,200
`2,010
`1,610
`2,030
`5,120
`1,000
`1,140
`3,380
`200
`4,800
`36,080
`Massachusetts
`7,010
`2,810
`2,470
`2,240
`8,190
`1,690
`1,700
`5,020
`320
`6,480
`53,550
`Michigan
`4,910
`1,200
`1,130
`890
`3,310
`890
`810
`2,520
`140
`3,280
`23,670
`Minnesota
`1,990
`540
`540
`380
`2,340
`360
`270
`1,480
`130
`1,820
`14,150
`Mississippi
`3,620
`1,450
`1,250
`1,260
`5,600
`880
`870
`3,100
`220
`3,880
`30,090
`Missouri
`810
`270
`240
`220
`730
`170
`140
`520
`T
`640
`5,340
`Montana
`1,410
`450
`400
`420
`1,230
`290
`270
`950
`60
`1,200
`8,810
`Nebraska
`1,660
`630
`480
`480
`1,910
`380
`270
`1,240
`110
`1,350
`12,020
`Nevada
`910
`420
`310
`460
`1,100
`210
`240
`730
`T
`1,010
`7,630
`New Hampshire
`6,060
`2,640
`2,160
`2,530
`6,250
`1,380
`1,620
`4,590
`410
`6,440
`47,920
`New Jersey
`1,400
`350
`360
`460
`970
`310
`210
`810
`80
`1,090
`8,830
`New Mexico
`12,520
`5,360
`4,540
`3,710
`13,550
`3,140
`3,510
`9,970
`870
`13,530
`101,550
`New York
`6,130
`1,790
`1,730
`2,190
`6,670
`1,150
`1,030
`4,230
`340
`5,470
`42,270
`North Carolina
`560
`180
`140
`110
`420
`110
`90
`350
`T
`410
`3,200
`North Dakota
`6,510
`2,990
`2,800
`2,080
`10,690
`1,950
`1,930
`6,060
`390
`7,340
`62,420
`Ohio
`2,190
`770
`820
`690
`3,220
`580
`400
`1,860
`140
`2,340
`18,110
`Oklahoma
`2,510
`1,020
`910
`1,220
`2,610
`490
`570
`1,780
`110
`2,680
`19,210
`Oregon
`8,130
`4,160
`3,330
`3,440
`10,480
`2,200
`2,550
`7,590
`500
`9,380
`74,170
`Pennsylvania
`650
`370
`260
`340
`900
`180
`190
`590
`T
`810
`6,250
`Rhode Island
`2,910
`880
`870
`1,090
`3,680
`590
`520
`2,150
`170
`2,820
`22,100
`South Carolina
`740
`230
`180
`180
`590
`140
`120
`440
`T
`530
`4,120
`South Dakota
`4,790
`1,380
`1,370
`1,410
`5,370
`1,000
`720
`3,490
`240
`3,970
`32,570
`Tennessee
`13,130
`3,720
`4,530
`3,820
`14,150
`3,470
`2,220
`9,800
`980
`13,090
`98,200
`Texas
`1,570
`360
`440
`600
`620
`330
`250
`770
`60
`1,080
`8,880
`Utah
`540
`190
`140
`200
`500
`100
`120
`330
`T
`480
`3,550
`Vermont
`4,830
`1,430
`1,450
`1,790
`5,330
`840
`1,020
`3,380
`240
`4,850
`34,150
`Virginia
`4,680
`1,660
`1,540
`1,970
`4,130
`990
`960
`2,890
`190
`4,520
`32,290
`Washington
`1,210
`510
`420
`450
`2,030
`290
`330
`1,070
`70
`1,180
`10,230
`West Virginia
`2,770
`1,530
`1,310
`1,040
`3,960
`980
`1,000
`2,770
`160
`3,480
`27,560
`Wisconsin
`390
`130
`110
`130
`320
`70
`70
`240
`T
`300
`2,500
`Wyoming
`192,290" 70,980“
`65,980
`68,720
`219,440
`44,790
`42,160
`146,970
`11,270
`192,370
`71,479,350
`United States
`* Rounded to nearest 10. Excludes basal and squamous cell skin cancers and in situ carcinomas except urinary bladder. t Estimate is fewer than 50 cases.
`Note: These estimates are offered as a rough guide and should be interpreted with caution. State estimates may not sum to US total due to rounding and exclusion
`of state estimates fewer than 50 cases.
`
`@2009, American Cancer Society, lnc., Surveillance and Health Policy Research
`
`Cancer Facts 8: Figures 2009
`
`5
`
`

`
`Estimated Cancer Deaths for Selected Cancer Sites by State, US, 2009*
`Brain/
`Nervous
`System
`200
`T
`280
`130
`1,460
`200
`150
`50
`T
`810
`
`Female Colon &
`Breast
`Rectum Leukemia
`700
`940
`340
`60
`70
`T
`740
`970
`410
`410
`580
`250
`4,030
`4,830
`2,200
`520
`670
`300
`480
`550
`270
`110
`150
`70
`70
`100
`50
`2,730
`3,460
`1,650
`
`Non-
`Hodgkin
`Lung &
`Liver Bronchus Lymphoma Ovary Pancreas Prostate
`280
`3,140
`290
`270
`550
`510
`T
`220
`T
`T
`50
`T
`360
`2,820
`350
`290
`630
`580
`190
`2,160
`200
`130
`400
`340
`2,450
`12,750
`1,900
`1,580
`3,740
`2,780
`210
`1,670
`230
`210
`430
`350
`210
`1,810
`220
`180
`540
`390
`50
`590
`50
`T
`110
`90
`T
`240
`T
`T
`60
`60
`1,300
`12,210
`1,560
`970
`2,470
`2,280
`
`State
`Alabama
`Alaska
`Arizona
`Arkansas
`California
`Colorado
`Connecticut
`Delaware
`Dist. of Columbia
`Florida
`
`All Sites
`9,900
`830
`10,260
`6,230
`54,600
`6,740
`6,990
`1,860
`970
`41,270
`
`Georgia
`Hawaii
`Idaho
`Illinois
`Indiana
`Iowa
`Kansas
`Kentucky
`Louisiana
`Maine
`
`14,970
`2,270
`2,450
`23,220
`12,820
`6,360
`5,290
`9,410
`8,810
`3,190
`
`320
`T
`90
`470
`290
`160
`150
`150
`210
`80
`
`1,130
`140
`160
`1,770
`860
`400
`370
`590
`690
`180
`
`1,370
`210
`200
`2,260
`1,130
`600
`510
`840
`910
`260
`
`550
`80
`120
`950
`520
`300
`200
`320
`310
`110
`
`400
`120
`80
`700
`350
`150
`140
`240
`330
`80
`
`4,660
`570
`630
`6,460
`4,000
`1,760
`1,620
`3,430
`2,700
`980
`
`460
`80
`80
`770
`420
`280
`180
`300
`310
`90
`
`400
`50
`50
`600
`340
`170
`150
`210
`210
`70
`
`870
`170
`200
`1,560
`770
`380
`330
`500
`530
`200
`
`800
`100
`160
`1,150
`520
`330
`210
`390
`450
`160
`
`810
`200
`10,320
`Maryland
`870
`270
`13,140
`Massachusetts
`1,350
`490
`20,450
`Michigan
`600
`230
`9,020
`Minnesota
`430
`160
`6,090
`Mississippi
`890
`270
`12,620
`Missouri
`120
`50
`1,980
`Montana
`210
`80
`3,360
`Nebraska
`330
`120
`4,600
`Nevada
`170
`70
`2,620
`New Hampshire
`1,470
`320
`16,480
`New Jersey
`240
`80
`3,300
`New Mexico
`2,550
`790
`34,190
`New York
`1,310
`330
`18,550
`North Carolina
`80
`T
`1,300
`North Dakota
`1,790
`550
`24,350
`Ohio
`520
`170
`7,420
`Oklahoma
`500
`210
`7,380
`Oregon
`2,070
`550
`28,690
`Pennsylvania
`130
`50
`2,220
`Rhode Island
`640
`190
`9,100
`South Carolina
`100
`T
`1,640
`South Dakota
`910
`350
`13,340
`Tennessee
`2,570
`850
`36,030
`Texas
`260
`100
`2,760
`Utah
`80
`T
`1,150
`Vermont
`1,140
`290
`13,920
`Virginia
`790
`380
`11,210
`Washington
`280
`90
`4,530
`West Virginia
`750
`260
`11,170
`Wisconsin
`60
`T
`990
`Wyoming
`40,170
`"12,920
`_-562,340
`United States
`* Rounded to nearest 10. TEstimate is fewer than 50 deaths.
`Note: State estimates may not sum to US total due to rounding and exclusion of state estimates fewer than 50 deaths.
`Source: US Mortality Data, 1969-2006, National Center for Health Statistics, Centers for Disease Control and Prevention, 2009.
`©2009, American Cancer Society, Inc., Surveillance and Health Policy Research
`
`
`
`6 Cancer l-acts & Figures 2009
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`940
`1,070
`1,720
`760
`600
`1,100
`170
`350
`500
`220
`1,580
`320
`3,110
`1,410
`120
`2,210
`600
`610
`2,550
`160
`780
`150
`1,140
`3,140
`240
`120
`1,270
`940
`430
`900
`100
`49,920
`
`2,880
`320
`390
`3,610
`420
`490
`5,840
`610
`820
`2,380
`260
`370
`2,030
`190
`220
`4,100
`360
`530
`550
`50
`90
`890
`80
`150
`1,340
`160
`140
`750
`70
`100
`4,190
`540
`610
`710
`150
`120
`8,780
`1,210
`1,380
`5,630
`470
`640
`370
`T
`50
`7,300
`640
`890
`2,390
`200
`290
`2,140
`210
`290
`8,090
`790
`1,080
`560
`70
`90
`2,880
`250
`330
`450
`T
`60
`4,520
`350
`480
`9,780
`1,650
`1,430
`480
`70
`130
`350
`T
`60
`4,250
`390
`500
`3,090
`410
`450
`1,500
`110
`140
`2,910
`320
`500
`260
`T
`T
`21,870 3 718,160i159,390
`
`300
`430
`710
`320
`180
`430
`70
`130
`130
`60
`610
`110
`1,430
`530
`T
`740
`_ 240
`330
`1,090
`70
`310
`70
`440
`1,300
`130
`T
`410
`410
`180
`400
`T
`19,500
`
`260
`350
`520
`240
`140
`290
`50
`90
`120
`60
`450
`90
`970
`430
`T
`580
`170
`220
`760
`60
`210
`50
`310
`890
`90
`T
`380
`340
`120
`300
`T
`14,600”
`
`690
`880
`1,250
`580
`350
`750
`120
`190
`280
`170
`1,080
`220
`2,360
`1,090
`90
`1,430
`380
`470
`1,920
`120
`530
`100
`730
`2,120
`190
`70
`880
`710
`210
`710
`60
`35,240
`
`550
`540
`820
`410
`300
`660
`120
`200
`230
`130
`660
`210
`1,470
`860
`100
`1,200
`280
`390
`1,440
`100
`420
`100
`570
`1,700
`170
`60
`620
`680
`140
`500
`T
`27,360
`
`

`
`
`
`Cancer Incidence Rates* by Site and State, US, 2001-2005
`
`All Sites
`
`Breast
`
`Colon &
`Rectum
`
`Lung &
`Bronchus
`
`Non-Hodgkin
`Lymphoma
`
`Prostate
`
`Urinary
`Bladder
`
`.
`
`1
`
`.
`,
`Male Female I Female Male Female Male Female Male Female
`7 555.6
`377.6
`I
`114.2
`62.2
`41.9
`109.5
`52.5
`20.5
`14.0
`533.2
`410.6
`127.9
`61.3
`46.0
`82.4
`62.8
`23.5
`16.1
`461.7
`363.0
`109.8
`49.4
`36.3
`69.8
`48.8
`18.6
`13.2
`5582
`381.5
`114.0
`59.2
`43.6
`113.4
`59.0
`21.9
`15.1
`
`_..s.
`State
`Alabama’
`Alaska‘
`Arizona
`Arkansas’
`
`California‘
`Colorado‘
`Connecticut‘
`Delaware“
`Dist. of Columbia‘
`Florida‘
`Georgia*
`Hawaii’
`Idaho’
`l||inois'
`
`Indiana’
`Iowa’
`Kansas‘
`Kentucky’
`Louisiana’
`
`Maine’
`Maryland‘
`Massachusetts‘
`Michigan‘
`Minnesota’
`Mississippi (2002-2005)
`Missouri’
`Montana‘
`Nebraska*
`Nevada’
`New Hampshire’
`New Jersey*
`New Mexico’
`New York’
`North Carolina*
`North Dakota’
`Ohio
`Oklahoma‘
`Oregon’
`Pennsylvania’
`
`Rhode Island‘
`South Carolina’
`South Dakota‘
`Tennessee§
`Texas‘
`Utah’
`Vermont‘
`Virginia
`Washington’
`West Virginia’
`Wisconsin‘
`Wyoming’
`United States
`
`J
`
`4
`
`124.7
`125.9
`137.4
`126.4
`—
`116.7
`120.6
`126.0
`118.2
`124.1
`
`117.7
`125.4
`—
`120.5
`120.9
`
`130.6
`——
`133.8
`127.0
`129.3
`105.8
`123.0
`122.6
`127.8
`116.0
`132.3
`129.8
`111.7
`124.6
`—
`122.5
`121.9
`126.4
`134.7
`125.7
`
`127.5
`119.2
`125.5
`115.3
`116.3
`112.9
`—
`119.5
`138.9
`115.3
`
`117.9
`123.6
`
`53.8
`51.5
`65.2
`62.6
`——
`67.7
`60.1
`62.4
`52.0
`68.0
`
`64.6
`67.2
`—
`70.3
`70.1
`
`67.7
`—
`67.6
`61.0
`57.9
`62.9
`64.7
`55.4
`68.5
`56.9
`61.7
`68.3
`50.8
`63.4
`—
`68.3
`62.7
`61.2
`54.4
`68.4
`
`67.8
`63.5
`63.8
`57.7
`59.5
`46.3
`—
`56.7
`54.6
`70.6
`
`49.4
`61.2
`
`39.8
`41.0
`47.9
`46.4
`—
`43.4
`42.6
`42.5
`38.5
`48.5
`
`47.3
`50.5
`——
`51.4
`48.3
`
`49.1
`—
`48.4
`45.7
`43.1
`45.2
`46.1
`41.5
`48.0
`43.1
`46.9
`50.0
`35.4
`47.2
`——
`44.1
`45.8
`43.9
`41.7
`49.6
`
`46.8
`44.9
`46.7
`42.2
`40.5
`34.1
`—
`42.3
`41.4
`51.7
`
`43.6
`44.8
`
`67.0
`63.0
`82.5
`97.8
`~—
`91.4
`104.1
`67.8
`69.6
`93.1
`
`_ 105.3
`I
`89.3
`—
`136.2
`111.3
`
`99.8
`—-
`86.0
`94.3
`71.4
`110.1
`105.4
`78.2
`84.5
`84.3
`82.3
`80.9
`59.1
`80.5
`—
`74.9
`97.2
`107.4
`79.9
`91.6
`
`94.5
`103.8
`80.3
`105.0
`90.4
`39.6
`—
`86.1
`80.5
`117.0
`
`62.6
`87.3
`
`47.5
`46.0
`58.8
`66.2
`~—
`60.8
`53.4
`38.9
`46.7
`57.8
`
`62.2
`52.4
`-—
`76.2
`58.2
`
`65.7
`—
`63.0
`61.3
`49.2
`50.9
`61.8
`57.9
`48.8
`69.5
`61.5
`56.0
`38.5
`53.7
`—-
`47.1
`58.9
`63.8
`60.4
`55.7
`
`59.5
`52.3
`45.0
`56.4
`51.2
`22.4
`—
`51.9
`60.0
`69.4
`
`47.2
`55.4
`
`:
`
`_
`
`22.6
`21.4
`25.5
`22.5
`~
`21.9
`20.6
`18.9
`21.5
`23.8
`
`22.6
`23.5
`—
`22.4
`22.9
`
`24.5
`—
`24.1
`25.0
`26.4
`19.9
`21.8
`23.2
`24.0
`21.9
`24.4
`25.9
`18.4
`24.3
`—
`22.6
`22.8
`22.3
`24.1
`24.8
`
`25.0
`20.6
`22.4
`19.4
`22.2
`22.9
`—
`19.6
`26.9
`22.3
`——
`20.6
`23.2
`
`15.5
`16.3
`17.8
`16.7
`—
`15.5
`14.2
`12.7
`17.2
`16.3
`
`16.0
`17.0
`—
`16.9
`16.2
`
`18.6
`—
`17.1
`18.5
`18.1
`13.0
`15.9
`15.0
`16.9
`15.0
`18.1
`17.7
`14.0
`16.9
`—
`15.3
`16.2
`16.2
`17.5
`17.3
`
`16.7
`14.5
`17.4
`14.2
`16.1
`15.8
`—
`13.1
`18.4
`16.0
`—-
`16.3
`16.3
`
`5
`'
`
`,
`V
`
`_
`
`i
`
`’
`i
`
`Male
`150.7
`151.3
`116.6
`158.1
`
`152.6
`159.4
`166.6
`175.5
`—
`143.1
`163.6
`129.3
`168.8
`159.5
`
`136.9
`147.3
`——
`144.4
`180.2
`
`166.8
`—
`170.2
`186.4
`185.9
`161.9
`131.5
`182.4
`157.3
`148.7
`162.7
`183.9
`149.3
`165.9
`——
`170.8
`145.6
`147.0
`151.4
`161.4
`
`161.6
`172.3
`183.0
`120.3
`146.6
`185.0
`—
`154.1
`167.7
`139.4
`—-
`171.2
`158.2
`
`.3
`I Male Female
`!
`31.1
`7.7
`E 39.4
`7.2
`35.0
`87
`33.1
`8.9
`
`34.4
`35.0
`44.6
`42.4
`—
`38.7
`33.0
`25.1
`38.4
`40.8
`
`37.2
`40.6
`—
`38.1
`35.6
`
`48.7
`—
`46.5
`42.5
`40.0
`28.3
`36.2
`41.9
`37.8
`43.0
`47.9
`46.0
`28.0
`42.1
`—
`36.7
`38.7
`33.8
`40.3
`44.6
`
`51.6
`32.6
`39.7
`31.5
`30.2
`29.1
`—
`32.1
`41.6
`40.0
`_ —
`41.5
`' 38.4
`
`8.3
`9.1
`12.5
`11.0
`—
`10.0
`8.1
`6.2
`8.5
`10.4
`
`9.3
`9.8
`——
`9.8
`8.7
`
`12.9
`—
`12.9
`10.7
`10.5
`7.4
`9.2
`9.3
`10.0
`11.2
`13.5
`12.2
`7.0
`11.2
`—
`9.9
`9.7
`8.1
`10.4
`11.3
`
`12.9
`7.7
`8.3
`7.8
`7.4
`6.4
`—
`8.3
`10.4
`114
`—
`9.5
`9.8
`
`518.2
`5127
`589.5
`601.7
`—
`549.3
`571.3
`484.9
`543.5
`1 580.1
`
`‘ 552.3
`) 560.9
`—
`612.5
`624.9
`
`396.4
`401.7
`454.3
`438.6
`—-
`410.1
`395.2
`385.9
`399.0
`426.8
`
`414.9
`428.3
`—
`447.1
`409.5
`
`621.6
`—
`604.0
`608.0
`5688
`5556
`545.3
`561.2
`557.0
`539.9
`586.7
`612.5
`490.7
`575.7
`—
`543.8
`543.8
`551.3
`533.4
`593.9
`
`616.7
`589.6
`568.5
`496.9
`546.5
`493.1
`—-
`515.6
`571.2
`576.0
`
`, 515.5
`i 562.3
`
`‘
`1
`i
`
`|
`460.6
`— I
`455.9
`440.2
`418.6
`3655
`414.6
`412.3
`417.9
`415.8
`451.9
`451.5
`367.7
`432.7
`——
`396.7
`413.6
`409.2
`430.0
`444.0
`
`|
`I
`
`I
`
`446.9
`395.2
`