throbber
DECLARATION or ARTHUR RIGGS
`
`15
`
`m -rm-: tmm-.n STATES PATENT AND TRADEMARK -brncs
`sax»-one -ms aonnn or PATENT APPEALS AND um-smrmzwcss
`
`Interrerenee No. 102.572
`
`Exlminenin-Chief
`Mary F. Downey
`
`))
`
`3 )
`
`)
`
`Cabilly et
`
`II
`
`V.
`
`Eon et at
`
`Efl&Afl
`
`1.
`
`I. Arthur Riggs. declare ind state that
`
`I am a citizen of the United States
`
`residing In LaVemc.. Cambmh. My Curriculum vine is attached It Cehilly et
`Exhibit No. 1.
`I an 1 co-inventor of the United States Patent 4.816.361 emitted
`‘Recombinant
`hnmunogtobultn Prep'tnHon$".
`'
`A
`2.
`I hve been employed by the City of Hope in Dunne. Cllifomh from
`
`:1
`
`June I969 to the present at Director. Department of Biology.
`
`‘
`
`3-
`
`Dmin! the period of July 1980 through September 1980.
`
`I was at
`
`Genenteeh on etbbotieal
`
`from the City of Hope. My intention was to explore the
`
`‘- ponibility of producing tnttbodies in bnctem. After my say at Geumeeh.
`
`I
`
`returned to the City of Hope where 1
`
`formulated 1 proposll whetoby Oenenteoh would
`
`ueitt
`
`in the funding of this pro}eet (cabifly Exhibit No. 2).
`
`The pyopead was bued in
`
`lubmttlld
`I
`pan on eonvetutiont between Dr." Heyneker. Samuel cabiny tad myself.
`shit proposal
`for review by Gene:-neeh on October 5. 1981.
`Include! in this propoett
`wu : research pin for
`the cloning. beetetm expression. and tltet-mien of both
`
`heavy and light ehlitt genes
`
`from a monoclonal
`
`tntibody direeteé cg-dust hutnu
`
`carclnoembryonic antigen (CEA).
`
`Furthen-not-e.
`
`I
`
`suggested in the. Pfwmsnl
`
`that
`
`(Clbilly Exhibit No. 2. Bite: No. 00922) 1 single bgctet-£31 strain tank! be’ e'on:tr-netted.
`
`which oontuned both hem-y and tight cheln genes
`ditcuuod during our earlier convenntlons,
`
`for co-exp:-eetiatt. an idea
`V
`
`-4.
`
`My experimental plan included the coluboration of Dr. Shmtrel Cabmy.
`
`renew in my laboratory M the City of Hope. end Dt.
`a post doctoral
`5 Senior Scientist at Genentech.
`
`t-Ietbert Heyneker.
`
`GNE-MED-02012
`
`GNEJGSKOOO03415
`
`GNE-HGS 00082026
`
`Mylan v. Genentech
`Mylan V. Genentech
`IPR2016-00710
`IPR2016'00710 GNE-LILLY-BMS 0008075
`Genentech Exhibit 2026
`Genentech Exhibit 2026
`GNE-REG00080759
`
`

`
`.
`DECLARATION OF ARTHUR RIGGS
`
`‘
`
`‘
`
`16
`
`lahn Shiveli “'55 15¢-C5‘? 01'
`I discussed this propcsed project with Dr.
`S.
`Hope. who was involved in the’ study of and-CEA antibodies.
`I 1-equated hum him a
`
`hybridoml. cefl
`
`tine that expressed lhcst‘. antibodies.
`
`2
`
`received this 69" 1130
`
`(CE.A.65-E3) on or about February. 1981.
`
`5.
`
`During the period of these studies 1 worked clasely with Dr. Csbllin who
`
`wax undct my dim: supervisien.
`
`In addition.
`
`I maintained regulu contact with Dr.
`
`Heyneker.
`
`_
`
`_
`
`7.
`
`I further dectare that all statements made of my 0% 1=M'‘''¢4I¢ 499 ‘N’
`
`and that all statements made on information and belief are believed 16 be tune: and
`
`further um these suxemenzs were met}: with the knovledte that willhll mu
`
`statement: and the like :6 and»: are punishable by fine or
`under Section 1001 of Tm: 28 of the United sates Code.
`
`imprisonment. or both.
`
` nma:
`
`/_",Z.2fA/2}’
`
`GNE-MED-02013
`
`GNE—(GSKOO0()'3416
`
`GNE-HGS 00082027
`
`GNE-LILLY-BMS 00080760
`
`GNE-REG00080760

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