throbber
(cid:55)(cid:85)(cid:68)(cid:81)(cid:86)(cid:70)(cid:85)(cid:76)(cid:83)(cid:87)(cid:3)(cid:82)(cid:73)(cid:3)(cid:45)(cid:72)(cid:73)(cid:73)(cid:72)(cid:85)(cid:86)(cid:82)(cid:81)(cid:3)(cid:41)(cid:82)(cid:82)(cid:87)(cid:72)(cid:15)(cid:3)(cid:51)(cid:75)(cid:17)(cid:39)(cid:17)
`
`(cid:39)(cid:68)(cid:87)(cid:72)(cid:29)(cid:3)(cid:36)(cid:83)(cid:85)(cid:76)(cid:79)(cid:3)(cid:21)(cid:20)(cid:15)(cid:3)(cid:21)(cid:19)(cid:20)(cid:25)
`
`(cid:38)(cid:68)(cid:86)(cid:72)(cid:29)(cid:3)(cid:54)(cid:68)(cid:81)(cid:82)(cid:73)(cid:76)(cid:16)(cid:36)(cid:89)(cid:72)(cid:81)(cid:87)(cid:76)(cid:86)(cid:3)(cid:56)(cid:17)(cid:54)(cid:17)(cid:15)(cid:3)(cid:47)(cid:47)(cid:38)(cid:15)(cid:3)(cid:72)(cid:87)(cid:3)(cid:68)(cid:79)(cid:17)(cid:3)(cid:16)(cid:89)(cid:16)(cid:3)(cid:42)(cid:72)(cid:81)(cid:72)(cid:81)(cid:87)(cid:72)(cid:70)(cid:75)(cid:15)(cid:3)(cid:44)(cid:81)(cid:70)(cid:17)(cid:15)(cid:3)(cid:72)(cid:87)(cid:3)(cid:68)(cid:79)(cid:17)(cid:3)(cid:11)(cid:51)(cid:55)(cid:36)(cid:37)(cid:12)
`
`(cid:51)(cid:79)(cid:68)(cid:81)(cid:72)(cid:87)(cid:3)(cid:39)(cid:72)(cid:83)(cid:82)(cid:86)(cid:15)(cid:3)(cid:47)(cid:47)(cid:38)
`(cid:51)(cid:75)(cid:82)(cid:81)(cid:72)(cid:29)(cid:3)(cid:27)(cid:27)(cid:27)(cid:16)(cid:23)(cid:22)(cid:22)(cid:16)(cid:22)(cid:26)(cid:25)(cid:26)
`(cid:41)(cid:68)(cid:91)(cid:29)(cid:3)(cid:27)(cid:27)(cid:27)(cid:16)(cid:24)(cid:19)(cid:22)(cid:16)(cid:22)(cid:26)(cid:25)(cid:26)
`(cid:40)(cid:80)(cid:68)(cid:76)(cid:79)(cid:29)(cid:3)(cid:87)(cid:85)(cid:68)(cid:81)(cid:86)(cid:70)(cid:85)(cid:76)(cid:83)(cid:87)(cid:86)(cid:35)(cid:83)(cid:79)(cid:68)(cid:81)(cid:72)(cid:87)(cid:71)(cid:72)(cid:83)(cid:82)(cid:86)(cid:17)(cid:70)(cid:82)(cid:80)
`(cid:44)(cid:81)(cid:87)(cid:72)(cid:85)(cid:81)(cid:72)(cid:87)(cid:29)(cid:3)(cid:90)(cid:90)(cid:90)(cid:17)(cid:83)(cid:79)(cid:68)(cid:81)(cid:72)(cid:87)(cid:71)(cid:72)(cid:83)(cid:82)(cid:86)(cid:17)(cid:70)(cid:82)(cid:80)
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`(cid:58)(cid:82)(cid:85)(cid:79)(cid:71)(cid:90)(cid:76)(cid:71)(cid:72)(cid:3)(cid:38)(cid:82)(cid:88)(cid:85)(cid:87)(cid:3)(cid:53)(cid:72)(cid:83)(cid:82)(cid:85)(cid:87)(cid:76)(cid:81)(cid:74)(cid:3)(cid:95)(cid:3)(cid:44)(cid:81)(cid:87)(cid:72)(cid:85)(cid:83)(cid:85)(cid:72)(cid:87)(cid:68)(cid:87)(cid:76)(cid:82)(cid:81)(cid:3)(cid:95)(cid:3)(cid:55)(cid:85)(cid:76)(cid:68)(cid:79)(cid:3)(cid:54)(cid:72)(cid:85)(cid:89)(cid:76)(cid:70)(cid:72)(cid:86)
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`Mylan v. Genentech
`IPR2016-00710
`Genentech Exhibit 2020
`
`

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` UNITED STATES PATENT AND TRADEMARK OFFICE
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` BEFORE THE PATENT TRIAL AND APPEAL BOARD
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`1
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`SANOFI-AVENTIS U.S. LLC :
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`AND REGENERON :
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`PHARMACEUTICALS, INC., :
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` Petitioners, : Case IPR2015-01624
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` v. : Patent 6,331,415
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`GENENTECH, INC. AND :
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`CITY OF HOPE, :
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` Patent Owners. :
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`- - - - - - - - - - - - -
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` VIDEOGRAPHED DEPOSITION OF
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` JEFFERSON FOOTE, Ph.D.
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` PALO ALTO, CALIFORNIA
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` Thursday, April 21, 2016
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` 9:01 a.m.
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`Job No.: 107825
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`Pages: 1 - 481
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`Reported By: Sandra Bunch VanderPol, CSR #3032
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`Videotaped Deposition of Jefferson Foote, Ph.D.
`Conducted on April 21, 2016
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`2
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` Deposition of JEFFERSON FOOTE, Ph.D., held at
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`the offices of:
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` Wilmer Cutler Pickering Hale & Dorr LLP
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` 950 Page Mill Road
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` Palo Alto, CA 94304
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` Phone: 650.858.6000
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` Pursuant to agreement, before Sandra Bunch
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`VanderPol, CSR #3032, in and for the State of
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`California.
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`PLANET DEPOS
`888.433.3767 | WWW.PLANETDEPOS.COM
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`Videotaped Deposition of Jefferson Foote, Ph.D.
`Conducted on April 21, 2016
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` A P P E A R A N C E S
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` ON BEHALF OF PETITIONERS SANOFI-AVENTIS U.S.
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` LLC and REGENERON PHARMACEUTICALS, INC.:
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` RICHARD J. McCORMICK, ESQUIRE
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`3
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` MAYER BROWN LLP
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` 1221 Avenue of the Americas
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` New York, New York 10020-1001
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` 212.506.2382.
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` -and-
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` JONATHAN H. KIM, ESQUIRE
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` MAYER BROWN LLP
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` 71 South Wacker Drive
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` Chicago, Illinois 60606-4637
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` 312.701.8592
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` -and-
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` PETER S. CHOI, ESQUIRE
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` SIDLEY AUSTIN LLP
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` 1501 K Street, N.W.
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` Washington, DC 20005
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` 202.736.8076
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`(Appearances continued on next page)
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`PLANET DEPOS
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`Videotaped Deposition of Jefferson Foote, Ph.D.
`Conducted on April 21, 2016
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` A P P E A R A N C E S C O N T I N U E D
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` ON BEHALF OF PATENT OWNERS GENENTECH, INC. and
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`4
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` CITY OF HOPE:
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` ROBERT J. GUNTHER, JR., ESQUIRE
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` JEFFREY A. DENNHARDT, ESQUIRE
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` WILMER CUTLER PICKERING HALE and DORR LLP
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` 7 World Trade Center, 250 Greenwich Street
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` New York, New York 10007
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` 212.230.8830
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` -and-
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` WILLIAM W. KIM, Ph.D.
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` OWEN ALLEN, ESQUIRE
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` 950 Page Mill Road
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` Palo Alto, California 94304
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` 650.858.602
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` -and-
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` BECKY A. WHITFIELD, Ph.D.
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` 60 State Street
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` Boston, Massachusetts 02109
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` -and-
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` NORA Q.E. PASSAMANECK, ESQUIRE
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` 1225 17th Street, Suite 2600
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` Denver, Colorado 80202
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` 720.274.3152
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`PLANET DEPOS
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`Videotaped Deposition of Jefferson Foote, Ph.D.
`Conducted on April 21, 2016
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` A P P E A R A N C E S C O N T I N U E D
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`5
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`ALSO PRESENT:
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` TOR E. SMELAND, J.D., Ph.D., Regeneron,
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` Executive Director, Intellectual Property
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` R. BRIAN MCCASLIN, ESQUIRE, Sanofi
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` Principal Counsel, Biologic Patents/Litigation
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` VIDEOGRAPHER: REYNALDO ABESAMIS, JR.
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` --o0o--
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`PLANET DEPOS
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`Videotaped Deposition of Jefferson Foote, Ph.D.
`Conducted on April 21, 2016
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`6
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` C O N T E N T S
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` Examination by: Page
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` MR. GUNTHER 12
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` MR. McCORMICK 391
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` MR. GUNTHER 451
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` --o0o--
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` E X H I B I T S
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`Exhibit # Description Page
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`Exhibit 1 Expert Report of Jefferson Foote, 15
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` Ph.D.
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`Exhibit 2 Rebuttal Expert Report of 16
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` Jefferson Foote, Ph.D.
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`Exhibit 3 Transcript of Jefferson Foote, 19
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` Ph.D., in re Glaxo Group vs.
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` Genentech, 12/9/11
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`Exhibit 4 Expert Report of Jefferson Foote, 21
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` Ph.D. in re Bristol-Myers Squibb
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` vs. Genentech
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`Exhibit 5 Rebuttal Expert Report of 22
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` Jefferson Foote, Ph.D. in re
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` Bristol-Myers Squibb vs. Genentech
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`Exhibit 6 Opening Expert Report of Jefferson 24
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` Foote, Ph.D. in re Sanofi-Aventis
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` vs. Genentech
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`PLANET DEPOS
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`Videotaped Deposition of Jefferson Foote, Ph.D.
`Conducted on April 21, 2016
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`7
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` E X H I B I T S
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` Exhibit # Description Page
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`Exhibit 7 Expert Report of Sir Gregory 168
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` Winter, CBE, FRS, Regarding
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` Invalidity of U.S. Patent Nos.
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` 6,331,415 and 7,923,221
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`Exhibit 8 Reply Expert Report of Sir Gregory 181
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` Winter, CBE, FRS Regarding
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` Invalidity of U.S. Patent Nos.
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` 6,331,415 and 7,923,221
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`Exhibit 9 Deposition transcript of Sir 187
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` Gregory Winter - Volume 1, 1/19/15
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` in re Eli Lilly vs. Genentech
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`Exhibit 10 Ullman et al. U.S. Patent No. 233
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` 3,996,345
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`Exhibit 11 Litman et al. U.S. Patent No. 239
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` 4,299,916
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`Exhibit 12 Ullman et al. U.S. Patent No. 244
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` 4,193,983
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`Exhibit 13 Zuk et al. U.S. Patent No. 248
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` 4,208,479
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`Exhibit 14 Diagram drawn at deposition 312
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`Exhibit 15 Bujard et al. U.S. Patent No. 313
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` 4,495,280 History File
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` ///
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`PLANET DEPOS
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`Videotaped Deposition of Jefferson Foote, Ph.D.
`Conducted on April 21, 2016
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`8
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` E X H I B I T S
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` Exhibit # Description Page
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`Exhibit 16 European Patent Specification, EP 361
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` 1 532 260 B1
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`Exhibit 1001 US Patent 6,331,415 B1 31
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`Exhibit 1002 Bujard et al. US Patent No. 208
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` 4,495,280
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`Exhibit 1003 Paper - Synthetic DNA and 116
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` Medicine, by Riggs & Itakura
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`Exhibit 1004 Article by Southern and Berg, 381
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` Transformation of Mammalian Cells
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` to Antibiotic Resistance with a
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` Bacterial Gene Under Control of
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` the SV40 Early Region Promoter
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`Exhibit 1006 Declaration of Jefferson Foote, 13
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` Ph.D. In support of
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` Sanofi-Aventis U.S. LLC and
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` Regeneron's Petition For Inter
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` Partes Review of U.S. Patent No.
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` 6,331,415
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`Exhibit 1012 Boss et al. U.S> Patent No. 414
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` 4,816,397
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`Exhibit 1027 Harris - Expression of eukaryotic 75
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` genes in E.coli
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`PLANET DEPOS
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`Videotaped Deposition of Jefferson Foote, Ph.D.
`Conducted on April 21, 2016
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` E X H I B I T S
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` Exhibit # Description Page
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`Exhibit 1033 Uhlin et al. U.S. Patent No. 194
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` 4,487,835
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`Exhibit 1034 Anderson et al. U.S. Patent No. 194
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` 4,371,614
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`Exhibit 1035 Comai U.S. Patent No. 4,762,785 194
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`Exhibit 1036 Taylor U.S. Patent No. 4,476,227 196
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`Exhibit 1037 Paddock U.S. Patent No. 4,362,867 197
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`Exhibit 1038 Salser et al. U.S. Patent No. 195
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` 4,396,601
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`Exhibit 1039 Milstein Wellcome Foundation 39
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` Lecture transcript
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`Exhibit 2005 Declaration of Dr. Timothy Roy 87
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` Harris for Merged Reexaminations
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` of U.S. Patent No. 6,331,415
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` (Cabilly, et al.)
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`Exhibit 2010 Transcript of Dr. Jefferson D. 22
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` Foote, Vol. 1, 1/9/15, in re
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` Bristol-Myers Squibb vs.
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` Genentech
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` --o0o--
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`Videotaped Deposition of Jefferson Foote, Ph.D.
`Conducted on April 21, 2016
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` QUESTIONS INSTRUCTED NOT TO ANSWER
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` Page Line
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` Q. Okay. Now, sir, was it your idea 212 10
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`10
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` to -- for this IPR to rely on Bujard as
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` the primary reference or did that come
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` from the lawyers?
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` --o0o--
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`Videotaped Deposition of Jefferson Foote, Ph.D.
`Conducted on April 21, 2016
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`11
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` P R O C E E D I N G S
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` THE VIDEOGRAPHER: Good morning. My name
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` is Reynaldo Abesamis, Jr., your videographer, and I
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` represent Planet Depos. Today's date is April 21,
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` 2016. And the time now is 9:07.
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` This is the start of disk labeled No. 1 of
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` the video deposition of Jefferson Foote, Ph.D. in
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` the matter of Sanofi-Aventis U.S. LLC, et al.,
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` versus Genentech, Inc., et al., Case No. IPR-
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` 201501624. This is taken on behalf of Patent
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` Owners.
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` Our court reporter today is Sandy
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` VanderPol, representing Planet Depos.
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` Counsel, please identify yourself,
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` starting with the questioning attorney.
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` MR. GUNTHER: For Genentech and City of
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` Hope, Bob Gunther, of the WilmerHale firm. With me
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` are my colleagues, Becky Whitfield, Nora
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` Passamaneck, Bill Kim, Owen Allen, and -- I think I
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` got everybody. Oh, and Jeffrey Dennhardt, who is
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` out of the room but will be coming in.
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` MR. McCORMICK: Rich McCormick, from Mayer
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` Brown, for Sanofi-Aventis and Regeneron. And my
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` colleagues can introduce themselves.
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` MR. KIM: Jonathan Kim, from Mayer Brown
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`Videotaped Deposition of Jefferson Foote, Ph.D.
`Conducted on April 21, 2016
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`12
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` from.
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` MR. SMELAND: Tor Smeland, for Regeneron
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` Pharmaceuticals, Incorporated.
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` MR. MC CASLIN: Brian McCaslin, from
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` Sanofi.
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` MR. CHOI: And Peter Choi of
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` Sanofi-Aventis, with Sidley Austin.
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` MR. DENNHARDT: Jeff Dennhardt, from
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` WilmerHale.
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` THE VIDEOGRAPHER: Would the reporter
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` please swear in the witness.
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` THE REPORTER: Raise your right hand,
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` please.
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` Do you solemnly swear or affirm that the
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` testimony you are about to give in this proceeding
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` will be the truth, the whole truth, and nothing but
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` the truth, so help you God?
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` THE WITNESS: I do.
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` EXAMINATION
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` BY MR. GUNTHER:
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` Q. Good morning, Dr. Foote.
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` A. Good morning.
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` Q. I put a couple of -- a stack of documents
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` in front of you, and I'd like to start by maybe
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` going through those. If you could grab those and
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`PLANET DEPOS
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`Videotaped Deposition of Jefferson Foote, Ph.D.
`Conducted on April 21, 2016
`
`13
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` put those in front of you.
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` The first document in this stack, if we
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` did this properly, should be your declaration which
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` is marked Sanofi-Aventis 1006. Is that what it
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` says?
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` A. Yes.
`
` (Exhibit No. 1006 was marked for
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` identification.)
`
` BY MR. GUNTHER:
`
` Q. Sir, that's the declaration that you filed
`
` in support of the petition in this IPR, correct?
`
` A. Correct.
`
` Q. Now, sir, have you had a chance, prior to
`
` coming into your deposition, to reread your
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` declaration?
`
` A. I have.
`
` Q. Do you have any changes or corrections or
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` additions that you would like to make to it?
`
` A. Actually, there was one very slight one
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` that just occurred to me.
`
` Q. Okay.
`
` A. It doesn't affect much, but -- oh, I might
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` not be able to find it. It regards to -- well, I
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` won't look for it. But it referred to DNA-1 and
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` DNA-2 being physically linked. And I think I meant
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`Videotaped Deposition of Jefferson Foote, Ph.D.
`Conducted on April 21, 2016
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`14
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` to say functionally linked.
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` Q. Okay.
`
` A. If we come to it, I will go over it again.
`
` Q. Let me just --
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` A. That was the only thing.
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` Q. Let's see if we can actually find that,
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` because we might as well -- if there's going to be
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` an adjustment, we might as well make it now.
`
` A. Yeah. I'm sorry to bring it up.
`
` Q. No. No. I asked you the question.
`
` A. Oh, here we go.
`
` Q. You got it?
`
` A. It's on the page where it says, "Because
`
` DNA I and DNA II are present in a single vector
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` physically unlinked." That, as written, doesn't
`
` make sense.
`
` Q. Okay.
`
` A. Because most of their DNAs were physically
`
` separate, so they couldn't be in a single vector.
`
` Q. And so how would you change that?
`
` A. I think if we change it to "functionally
`
` unlinked," it would read correctly.
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` Q. Okay. Functionally unlinked?
`
` A. Uh-huh. Yeah.
`
` Q. Let's do this, just so -- do you have a
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`Videotaped Deposition of Jefferson Foote, Ph.D.
`Conducted on April 21, 2016
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`15
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` pen?
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` A. I do.
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` Q. Why don't you just make that correction on
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` the exhibit, and then if you could initial and date
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` right next to -- right next to the line where you
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` make the correction.
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` A. Uh-huh.
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` (Witness marking on exhibit.)
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` A. There we go.
`
` Q. Okay. Thanks for that.
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` Anything else?
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` A. That was the only thing I saw.
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` Q. Okay. So then let's put that aside. And
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` if you can, take a look at the next exhibit in the
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` stack, which should, if we did this correctly, be
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` Foote Deposition Exhibit 1. And it's your expert
`
` report in the Glaxo versus Genentech litigation.
`
` A. Okay.
`
` Q. Do you have that, sir?
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` A. I have that right here.
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` (FOOTE Exhibit No. 1 was marked
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` for identification.)
`
` BY MR. GUNTHER:
`
` Q. Okay. And that is, in fact, a copy of
`
` your expert report that you submitted in that
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`Videotaped Deposition of Jefferson Foote, Ph.D.
`Conducted on April 21, 2016
`
`16
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` litigation, correct?
`
` A. I believe so, yes.
`
` Q. All right. And, sir, you had an
`
` opportunity during the course of that litigation to
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` correct any errors or --
`
` A. I did.
`
` Q. Okay. And are you aware of any, as you
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` sit here today?
`
` A. No. I haven't --
`
` Q. Okay. Do you recall making any
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` corrections to this at any point during the
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` litigation process?
`
` A. I don't recall if I did or not.
`
` Q. Okay.
`
` A. This was five years ago, it looks like.
`
` Q. No, I understand. I -- I will tell you
`
` that I've searched and haven't been able to locate
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` any such --
`
` A. Okay.
`
` Q. -- corrections, and so maybe we will just
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` go -- go from there.
`
` A. Right.
`
` (FOOTE Exhibit No. 2 was marked
`
` for identification.)
`
` ///
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`Videotaped Deposition of Jefferson Foote, Ph.D.
`Conducted on April 21, 2016
`
`17
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` BY MR. GUNTHER:
`
` Q. If you look at the next exhibit in the
`
` stack, this is marked as Foote Exhibit 2, and
`
` there's a covering page on it. But if you turn to
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` the next page, it says, "Rebuttal Expert Report of
`
` Jefferson Foote, Ph.D." Do you see that?
`
` A. I don't have a covering page, but I have
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` rebuttal expert report.
`
` Q. Okay. Fine. Maybe I just got an extra
`
` page in there.
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` So your first page is the actual cover
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` page; is that right? It has the caption, case
`
` caption on it?
`
` A. It does.
`
` Q. And, sir, this is a copy of the Rebuttal
`
` Expert Report that you filed in the Glaxo versus
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` Genentech litigation?
`
` A. It seems to be.
`
` Q. And, sir, you had an opportunity, again,
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` during the course of that litigation, to make any
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` changes or corrections to this, right?
`
` A. I think that's true. But I don't remember
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` if I changed it.
`
` Q. As you sit here today, you're not aware of
`
` any changes?
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`Videotaped Deposition of Jefferson Foote, Ph.D.
`Conducted on April 21, 2016
`
` A. That's right.
`
` Q. Same with respect to Foote Exhibit 1, as
`
` you sit here today, you're not aware of any
`
`18
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` changes?
`
` A. I'm not aware.
`
` MR. McCORMICK: Pardon me. You're not
`
` introducing these just yet? You may at some point.
`
` I just want to be able to know if you are going to
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` introduce them.
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` MR. GUNTHER: I have actually marked them
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` as exhibits. I'm not sure -- so I'm not sure of
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` what the difference is.
`
` MR. McCORMICK: Okay. Well, then I'm
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` going to object to them, then.
`
` MR. GUNTHER: Okay. Yeah. Yeah.
`
` MR. McCORMICK: Okay. I just want to make
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` sure I get my objection into the introduction of
`
` them --
`
` MR. GUNTHER: Got it. Got it.
`
` MR. McCORMICK: -- and we can hash
`
` everything out later.
`
` MR. GUNTHER: Okay. Fair enough.
`
` MR. McCORMICK: So I will object at this
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` time to Foote 1 and Foote 2 coming into evidence.
`
` MR. GUNTHER: Okay. And I'm not sure I'm
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`Videotaped Deposition of Jefferson Foote, Ph.D.
`Conducted on April 21, 2016
`
`19
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` putting them into evidence. But I'm just -- I'm
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` marking them -- I'm marking them on the record --
`
` MR. McCORMICK: Got it.
`
` MR. GUNTHER: -- for the purposes of this
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` deposition.
`
` MR. McCORMICK: Okay.
`
` (FOOTE Exhibit No. 3 was marked
`
` for identification.)
`
` BY MR. GUNTHER:
`
` Q. Okay. So, now, if you would look at the
`
` next document in the stack, it should be marked
`
` Foote Exhibit 3, and it purports to be a transcript
`
` of your deposition taken on December 9, 2011 in the
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` Glaxo litigation.
`
` And, sir, does that -- as you sit here
`
` today, is that -- is that the transcript of the
`
` deposition that you gave in the Glaxo litigation?
`
` A. This is.
`
` Q. Okay. And, sir, with respect to this
`
` deposition, you had an opportunity to make any
`
` changes or corrections to the transcript, correct?
`
` A. No, I didn't.
`
` Q. You did not. Okay.
`
` A. No.
`
` Q. So you were never provided a copy of this?
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`Videotaped Deposition of Jefferson Foote, Ph.D.
`Conducted on April 21, 2016
`
` A. Not at the time. I've seen one recently
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` and noticed some errors. But they are errors in
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`20
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` spelling mostly.
`
` Q. Typographical-type errors?
`
` A. That's right.
`
` Q. Okay. Did you -- did you reread this
`
` deposition in preparation for your deposition?
`
` A. I read parts of it.
`
` Q. Okay. And which -- were they parts that
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` you selected, or did somebody else select them for
`
` you?
`
` A. I -- I looked at it myself, but there were
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` certain parts that Mayer Brown attorneys drew my
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` attention to.
`
` Q. Okay. And those were the parts that you
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` reviewed?
`
` A. That's right.
`
` Q. Okay. All right. And --
`
` A. Just for an example of the type of errors,
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` here there's a scientist named Honjo who is spelled
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` Klonjo --
`
` Q. Okay.
`
` A. -- on page 14.
`
` Q. All right. That's sort of -- that type of
`
` thing is what you're talking about?
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`Videotaped Deposition of Jefferson Foote, Ph.D.
`Conducted on April 21, 2016
`
`21
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` A. That's right.
`
` Q. In rereading the selections of the
`
` deposition that you were directed to by Mayer
`
` Brown, did you see anything of a substantive nature
`
` that you believe was incorrect?
`
` A. No.
`
` Q. Okay. And, as you sit here today, sir, do
`
` you have a -- well, strike that.
`
` (FOOTE Exhibit No. 4 was marked
`
` for identification.)
`
` BY MR. GUNTHER:
`
` Q. Let's go to what we should have marked as
`
` Foote Exhibit 4. And on my copy it has Exhibit M
`
` on the front. Do you see that?
`
` A. Yes.
`
` Q. All right. And if you look -- this is
`
` double-sided. So if you look at the next page,
`
` that is a copy of -- the face page says, "Expert
`
` Report of Jefferson Foote." And this is in the
`
` Bristol-Myers V. Genentech litigation, correct?
`
` A. Correct.
`
` Q. And sir this is a copy of the report that
`
` you submitted in that litigation, Foote Exhibit 4?
`
` A. Yes.
`
` Q. And, sir, as you sit here today, are you
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`Videotaped Deposition of Jefferson Foote, Ph.D.
`Conducted on April 21, 2016
`
`22
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` aware of any errors or corrections or changes that
`
` you want to make to that declaration?
`
` A. I'm not aware of any errors that I want to
`
` make.
`
` (FOOTE Exhibit No. 5 was marked
`
` for identification.)
`
` BY MR. GUNTHER:
`
` Q. So let's go to Foote Deposition Exhibit 5,
`
` which is entitled, "Rebuttal Expert Report of
`
` Jefferson Foote." And this is in the Bristol-Myers
`
` litigation against Genentech as well.
`
` And my question to you, sir: Is this a
`
` copy of your Rebuttal Expert Report in that
`
` litigation?
`
` A. Yes.
`
` Q. And, sir, as you sit here today, are you
`
` aware of any changes or corrections that you either
`
` made in the past or would like to make now to that
`
` declaration --
`
` A. None --
`
` Q. -- to that expert report?
`
` A. None come to mind.
`
` (Exhibit No. 2010 was marked for
`
` identification.)
`
` ///
`
`PLANET DEPOS
`888.433.3767 | WWW.PLANETDEPOS.COM
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`

`
`Videotaped Deposition of Jefferson Foote, Ph.D.
`Conducted on April 21, 2016
`
`23
`
` BY MR. GUNTHER:
`
` Q. Okay. And, sir, what -- the next exhibit
`
` actually is an exhibit that's been marked in this
`
` IPR proceeding. It's Exhibit 2010.
`
` Do you see it down at the bottom right?
`
` There's like a --
`
` A. 2-0 -- sorry.
`
` Q. 2-0-1-0.
`
` A. Exhibit 210 [sic], yes.
`
` Q. 2010?
`
` A. Yes.
`
` Q. And, sir, this is a deposition transcript
`
` of a deposition that you gave on January 9, 2015,
`
` in the Bristol-Myers V. Genentech litigation; is
`
` that correct?
`
` A. I believe so, yes.
`
` Q. Sir, do you recall having an opportunity
`
` to read the transcript and make any corrections to
`
` it?
`
` A. I -- I don't recall whether the transcript
`
` was presented to me.
`
` Q. Okay. Did you read any select -- did you
`
` read this deposition in part or in full in
`
` preparing to give your testimony in this matter?
`
` A. I skimmed it, and -- as with the other
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`PLANET DEPOS
`888.433.3767 | WWW.PLANETDEPOS.COM
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`Videotaped Deposition of Jefferson Foote, Ph.D.
`Conducted on April 21, 2016
`
`24
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` one, Mayer Brown attorneys drew my attention to
`
` certain passages, but they were rather limited.
`
` Q. Okay. Do you recall, in terms of that
`
` reading, that review, any substantive errors that
`
` you picked up as you reviewed those portions of the
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` transcript?
`
` A. No.
`
` (FOOTE Exhibit No. 6 was marked
`
` for identification.)
`
` BY MR. GUNTHER:
`
` Q. All right. So if we could go to the next
`
` exhibit, which is Foote Deposition Exhibit 6, and
`
` this is titled, "Opening Expert Report of Jefferson
`
` Foote," in the Sanofi-Aventis versus City of Hope
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` litigation.
`
` And, sir, that's an expert report that you
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` just recently filed in that ongoing litigation,
`
` correct?
`
` A. Last week, I think. Yes.
`
` Q. Yes. Right.
`
` And, sir, the subject matter of that
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` litigation is the Cabilly III patent, correct?
`
` A. Yes.
`
` Q. And, sir, have you had an opportunity to
`
` review this Opening Expert Report? And I recognize
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`PLANET DEPOS
`888.433.3767 | WWW.PLANETDEPOS.COM
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`Videotaped Deposition of Jefferson Foote, Ph.D.
`Conducted on April 21, 2016
`
`25
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` it's relatively recent.
`
` A. No, I haven't.
`
` Q. Is there anything, as you sit here today,
`
` that you think you would like to correct, change,
`
` expand on in this report?
`
` A. No.
`
` MR. McCORMICK: Just while we're at a
`
` break, I will object to the introduction of all of
`
` these exhibits as evidence, with the exception of
`
` Exhibit 2010, which is -- you have already put in
`
` evidence.
`
` MR. GUNTHER: Okay.
`
` Q. Now, sir, focusing on your declaration in
`
` this

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