`
`CURRICULUM VITAE
`
`Frederick Peter Guengerich
`
`January 1, 1949; Pekin, Illinois
`
`Wife —Cheryl; Children —Phillip, Laura, Anna
`
`U.S.A.
`
`619 Georgetown Drive
`Nashville, Tennessee 37205
`
`(615) 322-2261 (Office)
`(615) 352-1559 (Home)
`(615) 343-0704 (Office FAX)
`e-mail:f.guengerich@vanderbilt.edu
`
`B.S.,University of Illinois, Urbana,
`Illinois (Agricultural Science) 1970
`Ph.D., Vanderbilt University, Nashville, Tennessee (Biochemistry) 1973 (with Professor
`H.P. Broquist)
`Thesis: "Studies on the Piperidine Alkaloids of Rhizoctonia
`
`leguminicola"
`
`Born:
`
`Family:
`
`Citizenship:
`
`Address:
`
`Telephone:
`
`Education:
`
`Professional A ppoi n tnzen ts:
`1973-75
`Postdoctoral Scholar, Department of Biologicai Chemistry
`University of Michigan Medical School, Ann Arbor, Michigan (with Professor M.J. Coon)
`
`1975-79
`
`1980-83
`
`1983-
`
`1981-2011
`
`Z007-Z01Z
`
`2010-2012
`
`2013
`
`2013-
`
`Assistant Professor of Biochemistry
`Vanderbilt University School of Medicine, Nashville, Tennessee
`
`Associate Professor of Biochemistry
`Vanderbilt University School of Medicine, Nashville, Tennessee
`
`Professor of Biochemistry
`Vanderbilt University School of Medicine, Nashville, Tennessee
`
`Director, Center in Molecular Toxicology
`Vanderbilt University School of Mcdicinc, Nashville, Tcnncsscc
`
`Harry Pearson Broquist Professor of Biochemistry
`Vanderbilt University School of Medicine, Nashville, Tennessee
`
`Interm Chair, Department of Biochemistry
`Vanderbilt University School of Medicine, Nashville, Tennessee
`
`Stanford Moore Professor of Biochemistry
`Vanderbilt University School of Medicine, Nashville, Tennessee
`
`Inagami Professor of Biochemistry
`Tadashi
`Vanderbilt University School of Mcdicinc, Nashville, Tcnncsscc
`
`Confidential
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`Research Interests:
`
`Honors:
`
`Mechanisms of activation and detoxication of chemical carcinogens and toxicants;
`of enzymes
`characterization
`involved in these processes
`
`and
`
`and Experimental
`
`University of Illinois, B.S.with University Honors (Bronze Tablet) (1970)
`Predoctoral Fellowship, United States Public Health Service (1970-1973)
`Postdoctoral Fellowship, United States Public Health Service (1974-1975)
`Research Career Development Awardee, United States Public Health Service (1978-1983)
`Achievement Award, Society of Toxicology (1982)
`Burroughs Wellcome Scholar in Toxicology (1983-1988)
`John Jacob Abel Award, American Society for Pharmacology
`Therapeutics
`(1984)
`International Life Sciences Institute (1985)
`Kenneth Morgareidge Award,
`Investigator Awards, National Cancer Institute (1987-1994,1994-2001)
`Outstanding
`Founders'ward
`for Outstanding Research Contributinns
`to Progress in Tnxicology,
`Industry Institute of Toxicology (1991)
`Chemical
`Bernard B. Brodie Award in Drug Metabolism, American Society for Pharmacology
`Experimental Therapeutics
`(1992)
`George H. Scott Award, Toxicology Forum (1994)
`Best Paper Award, Drug Metabolism and Disposition (1995)
`of Science (1997)
`AAAS Fellow (Chemistry), American Association for the Advancement
`scientists in terms of number of literature citations for
`Ranked 46th among all biomedical
`articles published and cited in the 1990s (Science Watch 9, 1-2, 1998)
`Recipient of School of Medicine Medal of Merit,
`the first given for Mentoring
`Postdoctoral Fellows and/or Residents
`in the Research Setting, Vanderbilt
`renamed the Guengerich Award in 2006 and
`University
`(2000) (subsequently
`to be awarded every other year)
`continues
`Thomson-Reuters Highly Cited Researchers, Biology k Biochemistry, also Pharmacology,
`1981-1999(ISIHighlyCited.corn)
`Earl Sutherland Prize for Achievement
`in Research, Vanderbilt University
`(2001)
`(Doctcur Honoris Causa) (2002), University of Paris
`Honorary Doctorate/Professorship
`(Universite Rene Descartes, Paris V)
`Fellow, World Innovation Foundation (2003); Honorary Member
`(2007)
`in Pharmacology k Toxicology, 1993-2003
`ISI, 3rd Most-cited Author
`(http:/ / www.in-cites.corn/
`scientists/ pha-10-aug2003.html)
`Faculty Award, Vanderbilt University
`Distinguished
`(2003)
`International Society for the Study of
`North American Scientific Achievement Award,
`Xenobiotics (2003)
`Sidney P. Colowick Faculty Research Award, Vanderbilt University School of Medicine
`(2004) (given annually for "excellence in research that serves as a platform for
`discovery in diverse research areas")
`President's Distinguished
`Service Award, American College of Toxicology (2004)
`W~. C. Rose Award, American Snciety for Biochemistry and Molecular Biolngy (2005)
`MERIT Award, NIH grant R37 CA090426 (2006-2016)
`ranked first in world in total citation score
`Drug Metabolism Reasearch,
`(htt: www.c
`tochrome.net)
`(2006-present)
`(one of the first two foreign recipients), Japanese Society for the Study
`Honorary Member
`of Xenobiotics (2007)
`Institute of Biology
`(2008) Chinese Academy of Sciences/Chengdu
`Honorary Professor
`AACR Award for Outstanding Achievement
`in Chemistry in Cancer Research, American
`Association for Cancer Research (2009)
`
`Confidential
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`ACS Fellow, American Chemical Society (2009) (inaugural
`class)
`R.T. Williams Distinguished
`International Society for the
`Scientific Achievement Award,
`Study of Xenobiotics (2010)
`Founders'ward, Division of Chemical Toxicology, American Chemical Society (2011)
`Merit Award, Society of Toxicology (2013)
`Mentor of thc Year Award (2013), Vanderbilt Postdoctoral Association
`Hirsch Index (h-index): 131 (18 June 2015, ISI/Thomson Reuters)
`
`Distinguished Leetureships:
`
`and Toxicology, East Carolina University
`
`Irish Area Section Lecture, The Biochemical Society, 75th Anniversary Meeting, Dublin
`(1986)
`Distinguished Lecturer, Guelph-Waterloo Centre for Graduate Work in Chemistry (1988)
`Invited Lecturer, National Science Council, Republic of China (1988)
`Fricdcnwald Memorial Lccturc, Medical Grand Rounds, University of Maryland Medical
`School (1989)
`Hunter Memorial Lecture in Pharmacology
`(1989)
`Carmela Louise Riker Memorial Lecture, Oregon Health Sciences University
`(1993)
`Charles W. Gowdey Distinguished Lecture, University of Western Ontario (1995)
`'I'ufts University
`Sterling Lecture,
`(1996)
`Samuel Kuna Distinguished Lecture in Toxicology, Rutgers University
`(1997)
`John G. Wagner Lectureship Award in Pharmaceutics, University of Michigan (1997)
`J. Clarence Karcher Lecture, Department of Chemistry and Biochemistry, University of
`Oklahoma
`(2002)
`Keynote Lecture, Gordon Conference on Drug Metabolism (2002)
`Ralph J. Cazort Heritage Lecture, Meharry Medical College (2004)
`Chemistry Graduate Student Association Distinguished Lccturcr, Northcastcrn
`University
`(2004)
`Lilly Lecturer, Eli Lilly (2006)
`Distinguished Scientist Keynote Lecture Series, Istituto di Ricerca di Molecolare
`Biologica/Merck, Pomezia,
`Italy (2007)
`Jack Omdahl Memorial Lecture, University of New Mexico (2009)
`Bloch Lectures, Univeristy of Louisville (2010)
`Dis tinguished Lec turer, Hoff man-LaRoche
`(2010)
`(visiting professorship), University of Cagliari, Sardinia,
`Visiting Lecturer
`Visiting Scholar (visiting professorship), University of Tokyo (2012)
`2013 Biochemistry Alumni Lecture, School of Chemistry and Molecular Biosciences,
`University of Queensland, Brisbane (Australia)
`(2013)
`Guest Professor, Third Military Medical University, Chongqing (People's Republic of
`(2014)
`China)
`Visiting Professor, School of Pharmacy, National Defense Medical Center, Taipei
`(Taiwan, Republic of China)
`(2015)
`
`Italy (2011)
`
`Memberships:
`
`Alpha Zeta (1968)
`Phi Kappa Phi (1969)
`Gamma Sigma Delta (1970)
`Sigma Xi (1973)
`American Chemical Society (1976- )
`American Society for Biochemistry and Molecular Biology (1978- )
`Society of Toxicology (1978- )
`
`Confidential
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`
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`Service:
`
`American Society for Pharmacology
`and Experimental Therapeutics
`American Association for Cancer Research (1983- )
`International Society for the Study of Xenobiotics (1993-
`Environmental Mutagen Society (2010-
`)
`
`)
`
`(1979- )
`
`NIH Physical Biochemistry Study Section, Member
`(1979-1983)
`NIH Environmental Health Sciences Review Committee
`(Study Section), Member
`1991)
`(1994-1998)
`NIH Chemical Pathology Study Section, Member
`Institute of Environmental Health Sciences, Member
`NIH Advisory Council, National
`(2001-2005)
`NIH Study Section (SEP), Systemic Injury by Environmental Exposure, Member and
`Chair (2008-2009)
`
`(1987-
`
`Associate Editor, TOXICOLOGY AND APPLIED PHARMACOLOGY (1980-1984)
`Associate Editor, MOLECULAR PHARMACOLOGY (1982-1985)
`Associate Editor, CHEMICAL RESEARCH IN TOXICOLOGY (1989-)
`Associate Editor, CANCER RESEARCH (1985-1989,1993-2003)
`Associate Editor, THE JOURNAL OF BIOLOGICAL CHEMISTRY (2006-
`Deputy Editor, THE JOURNAL OF BIOLOGICAL CHEMISTRY (2013-
`)
`Interim Editor-in-Chief, THE JOURNAL OF BIOLOGICAL CHEMISTRY (2015-
`
`)
`
`)
`
`Editorial Board, FUNDAMEN'I'AL AND APPLIED TOXICOLOGY (1981-1986)
`Editorial Board, ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (1982-2006)
`Editorial Board, THE JOURNAL OF BIOLOGICAL CHEMISTRY (1984-1989,1991-1996,
`1997-2002, 2003-2006)
`Editorial Board, JOURNAL OF THE AMERICAN COLLEGE OF TOXICOLOGY
`(1984-1996)
`Editorial Board, XENOBIOTICA (1985-2003)
`Editorial Board, TOXICOLOGY AND APPLIED PHARMACOLOGY (1985-2001)
`Editorial Board, CHEMICAL RESEARCH IN TOXICOLOGY (1987-1989)
`Editorial Board, CANCER EPIDEMIOLOGY, BIOMARKERS, AND PREVENTION (1990-
`1998)
`Editorial Board, MOLECULAR PHARMACOLOGY (1991-2006)
`Editorial Board, APPLIED BIOLOGICAL SCIENCE (1994-2006)
`Advisory Board, CRITICAL REVIEWS IN TOXICOLOGY (1986-
`)
`Editorial Advisory Board, METHODS IN TOXICOLOGY (1989-1991)
`Editorial Advisory Board, PROTEIN EXPRESSION AND PURIFICATION (1990-2003)
`Editorial Advisory Board, DRUG METABOLISM AND DISPOSITION (1994-1999)
`Scientific Advisory Board, DRUG METABOLISM AND DISPOSITION (2000-2006)
`Editorial Board, ANALYTICAL BIOCHEMISTRY (1995-2003)
`Editorial Advisory Board, BIOCHEMICAL PHARMACOLOGY (1996-2003)
`Editorial Advisory Board, INTERNATIONAL JOURNAL OF ONCOLOGY (1996-2006)
`Editorial Board, ENVIRONMENTAL HEALTH PERSPECTIVES (1997-2004)
`Editorial Board, DRUG METABOLISM REVIEWS (1997-2006)
`Editorial Board, INSCRIPT, Academic Press (1998-2006)
`Editorial Board, INSCIGHT, Academic Press (1999-2006)
`Editorial Board, MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR
`MECHANISMS OF MUTAGENESIS (2000-2002)
`Editorial Board, DRUG METABOLISM AND PHARMACOKINETICS (2002-2006)
`
`Confidential
`
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`Honorary Editorial Board, AMERICAN JOURNAL OF PHARMACOGENOMICS
`2005)
`Honorary Editorial Board, APPLIED GENOMICS AND PROTEOMICS (2001-2003)
`Advisory Panel, NATURE REVIEWS, DRUG DISCOVERY (2001-
`)
`Editorial Advisory Board, CHEMISTRY & BIODIVERSITY (2004-
`)
`Editorial Board, PREVENTIVE MEDICINE AND CANCER PREVENTION (2003-2006)
`Editorial Advisory Board, CURRENT DRUG METABOLISM (2005-2006)
`Editorial Board, MOLECULAR DIAGNOSIS & THERAPY (2006)
`Editorial Board, TOXICOLOGICAL RESEARCH (2008-
`)
`
`(2001-
`
`and Experimental
`
`Panel on Cytochrome P-450 Nomenclature,
`Int. Union Biochemistry/Int. Union Pure
`Appl. Chemistry Joint Commission on Biochemical Nomenclature
`(1980)
`(1980-1981,1983-1984)
`Society of Toxicology, Awards Committee
`Joint American Society of Pharmacology
`and Experimental
`Program Committee,
`of Toxicology Meeting (1981-1982)
`Therapeutics/Society
`Gordon Research Conference on Food and Nutrition, Discussion Leader, Session on
`Effects of Nutritive Factors on Functions of Hydroxylases
`and Conjugating
`in Bioactivation and Detoxication (1982)
`Enzymes
`Society of Toxicology, Program Committcc (1982-1985)
`Society of Toxicology, Liaison to American Society for Pharmacology
`(1982-1984)
`Therapeutics
`Society of Toxicology, Membership Committee
`(1985-1987)
`American Society for Pharmacology
`and Experimental Therapeutics, Drug Metabolism
`(1985-1987)
`Division, Executive Committee
`American Society for Pharmacology
`'I'herapeutics, Drug Metabolism
`and Experimental
`Division, Committee for selection of best paper appearing in DRUG
`METABOLISM AND DISPOSITION (1985-1986;1986-1987)
`Gordon Research Conference on Drug Metabolism, Discussion Leader, Session on
`Suicide Inactivators of Oxidative Enzymes
`(1986)
`American Chemical Society, task force for consideration of a new journal
`for Division of Biological Chemistry (1986)
`representative
`International Advisory Committcc, Scvcnth International
`Symposium on Microsomcs
`and Drug Oxidations, Adelaide (1987)
`Gordon Research Conference on Drug Metabolism, Vice-Chairman
`(1987)
`Gordon Research Conference on Drug Metabolism, Chairman (1988)
`International Symposium on Biological
`International Scientific Advisory Committee,
`Oxidation Systems, Bangalore (1989)
`International Advisory Committee, Eighth international
`Drug Oxidations, Stockholm (1990)
`Society of Toxicology, Molecular Biology Section, Nominating Committee
`(1988, 1989)
`(1989-1993,Chairman 1991-1993)
`Society of Toxicology, Board of Publications
`Biological Abstracts
`(Biosciences Information Services), Consultant
`Organizing Committee, Symposium in Honor of Professor Minor J. Coon, University of
`Michigan (1990)
`International Union of Biochemistry and Molecular Biology, Biocncrgctics and Redox
`Systems Interest Group (1991-
`)
`National Cancer Institute, Working Group on Head and Neck Cancer (1991)
`American Association for Cancer Research, Exhibits Committee
`(1992-1994)
`International Union of Biochemistry and Molecular Biology, 16th International Congress
`(New Delhi), Symposium on Drug Metabolism and Cytochrome P450 Convenor
`(1994)
`
`in toxicology,
`
`Symposium on Microsomes and
`
`Confidential
`
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`
`
`International Advisory Committee, Fifth Biological Reactive Intermediates Meeting,
`Munich (1995)
`Fourteenth International Symposium on Cancer, Sapporo Cancer Seminar on Genetic
`Polymorphism and Cancer Susceptibility, Sapporo Organizing Committee
`(1994)
`American Chemical Society, Division of Chemical Toxicology, Organizing Committee
`(1994)
`International Congress of Toxicology-VII, Chairman, Continuing Education Course,
`in Xenobiotic Metabolism, Seattle (1995)
`Recent Advances
`American Society for Pharmacology
`and Experimental Therapeutics,
`Committee
`(1995)
`American Association for Cancer Research, Board of Publications
`2012)
`International Advisory Committee, European ISSX Workshop 1996, Sitges (Spain)
`International Society for the Study of Xenobiotics (1996-1999)
`Councilor,
`International Scientific Committee, 11th International Conference on Cytochrome P450
`Biochemistry, Biophysics, and Molecular Biology, Sendai (1999)
`American Chemical Society, Division of Chemical Toxicology, Program Committee
`(1997-2000, 2003- 2006)
`International Confcrcnccs on Cytochromc
`International Scientific Committcc,
`Chairman,
`P450: Biochemistry, Biophysics, and Molecular Biology (1998- )
`Chairman, Meeting Organizing Committee and Scientific Advisory Committee, North
`American International Society for the Study of Xenobiotics/American
`Chemical
`Society Division of Chemical Toxicology Combined Meeting, Nashville
`(1999)
`Program Committee, Amer. Assoc. Cancer Res. Annual Meeting, Molecular
`and Repair Section
`Carcinogenesis: Metabolism, DNA Lesions, Mutagenesis
`(1999)
`of Chemical Toxicology (1999-2001)
`Councilor, American Chemical Society/Division
`Scientific Advisory Committee, 10th North American Meeting,
`International Society for
`the Study of Xenobiotics, Nashville
`(1999)
`Organizing Committee, 48th Symposium of the Alfred Benzon Foundation, Drug
`Metabolism: Regulation and Importance
`(Copenhagen, September 2001)
`International Mccting, International Society for thc Study
`Scientific Advisory Committcc,
`of Xenobiotics (Indianapolis,
`2000)
`International Society for the Study of Xenobiotics (2000-2003)
`Nominating Committee,
`Joint Board-Council Committee on Publications, American Chemical Society (2000)
`Public Affairs Committee, American Society for Biochemistry and Molecular Biology
`(2000-2003)
`International Advisory Committee, 14th International
`Drug Oxidations, Sapporo (2002)
`Scientific Advisory Committee, European Meeting,
`Xenobiotics (Dijon, 2003)
`International Advisory Board, 15th International Conference on Microsomes and Drug
`Oxidations, Mainz (2004)
`Program Planning Committee, 7th International Meeting,
`Study of Xcnobiotics (Vancouver, 2004)
`Gordon Research Conference on Drug Metabolism, Discussion Leader, Session on
`Biochemistry of Drug-Induced Cellular Damage (2004)
`International Society for the Study of Xenobiotics (2005)
`Scientific Advisory Committee,
`Joint North American —Japan Meeting,
`Scientific Planning Committee,
`International
`Society for the Study of Xenobiotics (2005)
`Council, American Society for Biochemistry and Molecular Biology (2003-2006)
`
`International
`
`Society for the
`
`Confidential
`
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`John J. Abel Award
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`(1995-1997),(2009-
`
`Symposium on Microsomes and
`
`International Society for the Study of
`
`Vanda Exhibit 2002 - Page 6
`
`
`
`International Scientific Advisory Board, 16th International Conference on Microsomes
`and Drug Oxidations, Budapest
`(2006)
`Chair-Elect, Division of Chemical Toxicology, American Chemical Society (2005-2006)
`Chair, Division of Chemical Toxicology, American Chemical Society (2007-2008)
`B. B. Brndie Award Committee, Division of Drug Metabolism, American Society fnr
`(2005-2009, 2009-2013)
`and Experimental Therapeutics
`Pharmacology
`Intenational Society for the Study of Xenobiotics (2006-2009)
`Nominating Committee,
`International Advisory Committee, 18th International Conference on Microsomes and
`Drug Oxidations, Beijing (2010)
`Steering Committee, Chemistry in Cancer Research Working Group, American
`Association for Cancer Research (2009-2011)
`AACR Laboratory Research Awards Selection Committee, Member, American
`Association for Cancer Research (2009-2011)
`Publications Committee, American Association for Cancer Research (2010-
`)
`Division Income Subcommittee, Finance and Development Committee, Division of
`Chemical Toxicology, American Chemical Society (2010-
`)
`Nominating Committee, Division of Chemical Toxicology, American Chemical Society
`(2011-2013)
`International Advisory Committee, 19th International Conference on Microsomcs and
`Drug Oxidations/12th Europ. Int. Soc. Study Xenobiotics Joint Meeting,
`Noordwijk aan Zee, Netherlands
`(2012)
`Selection Committee, AACR Award for Outstanding Achievement
`Assoc. Cancer Res. (2012)
`International Society for the Study of Xenobiotics (ISSX) (2014-
`Awards Committee,
`
`in Chemistry, Amer.
`
`)
`
`Llniversity Teaching nnd Vnnderbilt Llniversity Service:
`
`(1976-1984,1986-1988,
`
`Biochemistry 322, Biochemistry Laboratory for Graduate Students
`Chair, 1978-1983)
`in Biochemical Literature (1976-1978,Chair, 1977-1978)
`Biochemistry 327, Seminar
`(1981-1984,1986-, Chair,
`Biochemistry 336, Biochemical Toxicology and Carcinogenesis
`1981-1984,1986-2011)
`Biochemistry 334, Chemical Mechanisms of Enzymatic Catalysis
`(1977-1992)
`Biochemistry 5012, Molecular Mechanisms of Disease (Biochemistry Lectures for
`(1981-1984,1986-2007)
`Advanced First Year Medical Students)
`(1993-2004)
`Biochemistry 330, Scientific Communication
`Biochemistry 301, Molecular Structure and Function (1994-, Chair, 1997-2004)
`Chemistry 305, Inorganic Chemistry (1988)
`Molecular Biology 312, Bioenergetics
`(1978-1982)
`324-3, Drug Metabolism (1981-1993)
`Pharmacology
`Pharmacology 501 (1991)
`Drug and Device Development, Master of Science in Clinical Investigation Program 524-
`5000 (2001-
`)
`Meharry Medical College, Occupational Toxicology (1991,1993,1995)
`Cancer Biology 344 (2008)
`Pathology 337, Molecular and Cellular Basis of Vascular Diseases (2014)
`
`(1977-1982,1987-2000, Director of
`Departmental Graduate Education Committee
`Graduate Recruitment, 1979-1982,1994-1997)
`(1979-1984)
`Departmental Safety Committee
`University Graduate Faculty Council (1980-1983),Executive Committee
`
`(1982-1983)
`
`Confidential
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`
`
`and
`
`)
`
`(1983-1985)
`Departmental Medical Education Committee
`American Cancer Society Grant Review Group (1979-1980)
`Toxicology (1980-1981)
`Acting Director, Center in Environmental
`Committee on Basic Research for Vanderbilt Cancer Center (1982-1985)
`(1982-1986, Chairman, 1982-1986)
`University Advisory Committee on Toxic Hazards
`Advisory Committcc for Pcptidc Analysis and Scqucncing Facility (1983-2002), Chairman
`(1996-2002)
`Graduate School Review Committee of the Graduate Program in Environmental
`Water Resources Engineering, Chairman (1984-1985)
`Search Committee for Chairman of the Department of Microbiology (1984-1985)
`Search Committee for Stahlman Chair in Cancer Research, Co-Chairman (1986-1988)
`Advisory Committee for Tandem Sector Mass Spectrometer
`(1988-1989),Chairman
`University Research Council (1988-1991)
`Advisory Committee for High Resolution Mass Spectrometer
`(1990),Chairman
`Ad /zoc Committee on Interdisciplinary Grant Proposals, The Graduate School (1990)
`Self-Study Task Force for Basic Science Departments, School of Medicine (1990-1991)
`Selection Committee for New Investigator Award Sponsored by Boehringer-Ingelheim
`Pharmaceutical
`s, Chairman
`(1992)
`Thc Gcorgc Daniel Brooks Lccturcship in Oncology Committcc (1992-1993)
`(1993-1995)
`Cancer Center, Program Leader, Cancer Pharmacology
`Graduate Education Committee, School of Medicine (1994-1997)
`(1994-1997)
`Interdisciplinary Graduate Program Committee
`Task Force on Basic Science Initiatives, School of Medicine (1996)
`Task Force on Technology Transfer, School of Medicine (1996)
`Search Committee, Faculty Position in Mass Spectrometry (1996-1997)
`Oversight Committee, Mass Spectrometry Resource (1996-
`)
`(1997-
`NMR (small molecule) Center Committee
`)
`Search Committee, Faculty Position NMR Spectroscopy (1997-1999)
`Search Committee, Chair of the Department of Pharmacology
`(1999-2000)
`Internal Advisory Committee, Pharmacogenomics U01 grant application (1999)
`Committee on Postdoctoral Affairs, School of Medicine (1999-2003)
`Environmental Affairs Committcc (2000-2004)
`Advisory Committee on Proteomics, School of Medicine (2001-
`Advisory Board, Conference on Proteomics
`(2002)
`Working Group, Trans-institutional
`Laboratory Security and Accountability
`(2002)
`Advisory Committee, High Throughput Biology Core/Molecular Recognition Shared
`Reso urce (2002-2006)
`Discovery Grant Review Committee, School of Medicine (2003)
`Internal Advisory Board, Center for Structural Biology (2004-2006)
`Chemical Safety Committee
`(2004-2016), Chair (2008-2016)
`Chair, search committee for head of Drug Toxicity Program (2007-2011)
`Basic Science Planning Committee, Enhancing the Reputation of Vanderbilt Research
`(2007)
`(2010-2013)
`Institutional Shared Resoures Oversight Committee
`Chemical & Physical Biology Training Program, Exccutivc Committcc (2011-2012)
`Member, Executive Committee of the Executive Faculty, School of Medicine (2011-2012)
`(2012-
`Member, School of Medicine Faculty Appointments & Promotions Committee
`2014)
`Member, Medical Center Tenure Review Committee
`
`(2014-2017)
`
`Confidential
`
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`Ad hoc reviewer for articles sub>nitted to:
`
`ACCOUNTS OF CHEMICAL RESEARCH
`ACTA CHIMICA SLOVENICA
`ACTA OBSTETRICA ET GYNECOLOGIA SCANDANAVIA
`AMB EXPRESS
`AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
`AMB EXPRESS
`AMERICAN JOURNAL OF PHARMACOGENETICS
`AMERICAN JOURNAL OF PHARMACOGENOMICS
`AMERICAN JOURNAL OF PHYSIOLOGY
`AMEPICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
`ANALYTICAL BIOCHEMISTRY
`ANALYTICAL CHEMISTRY
`ANESTHESIOLOGY
`ANGEWENDTE CHEMIE
`APPLIED AND ENVIRONMENTAL MICROBIOLOGY
`AQUATIC TOXICOLOGY
`ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
`ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
`ARCHIVES OF TOXICOLOGY
`ASIA PACIFIC JOURNAL OF MOLECULAR BIOLOGY AND BIOTECHNOLOGY
`AUSTRALIAN JOURNAL OF CHEMISTRY
`BIOCHEMICAL JOURNAL
`BIOCHEMICAL PHARMACOLOGY
`BIOCHEMISTRY
`BIOCHIMICA BIOPHYSICA ACTA
`BIOLOGICAL CHEMISTRY HOPPE-SEYLER
`BIOMEDICAL AND ENVIRONMENTAL SCIENCES
`BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS
`BIOORGANIC CHEMISTRY
`BIOPHARMACEUTICS AND DRUG DISPOSITION
`BIOTECHNIQUES
`BIOTECHNOLOGY AND BIOENGINEERING
`BRITISH JOURNAL OF CANCER
`BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
`CANADIAN JOURNAL OF CHEMISTRY
`CANADIAN JOURNAL OF MICROBIOLOGY
`CANCER CHEMOTHERAPY AND PHARMACOLOGY
`CANCER INVESTIGATION
`CANCER LETTERS
`CANCER RESEARCH
`CARCINOGENESIS
`CHEMCATCHEM
`CHEMICAL RESEARCH IN TOXICOLOGY
`CHEMICAL REVIEWS
`CHEMICAL SCIENCE
`CHEMICO-BIOLOGICAL INTERACTIONS
`CHEMISTRY k BIOLOGY
`CHEMTRACTS
`CLINICAL CANCER RESEARCH
`
`Confidential
`
`VNDA 02699343
`
`Vanda Exhibit 2002 - Page 9
`
`
`
`COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS
`COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY
`CURRENT DRUG METABOLISM
`CUv.v.ENT PI IARMAcoGENDMIcs
`DNA AND CEI.I.BIOI.()GY
`DNA REPAIR
`DEVELOPMENTAL PHARMACOLOGY AND THERAPEUTICS
`DIABETES
`DRUG DISCOVERY TODAY
`DRUG METABOLISM AND DISPOSITION
`DRUG METABOLISM REVIEWS
`DRUGS
`ENVIRONMENTAL HEALTH PERSPECTIVES
`ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
`EUROPEAN JOURNAL OF BIOCHEMISTRY
`EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
`EUvoPEAN JDURNAL DF PI IARMAcoLDG Y
`FASEB JC)UItNAI,
`FEBSJOURNAL
`FEBS LETTERS
`FOOD AND CHEMICAL TOXICOLOGY
`FREE RADICAL BIOLOGY AND MEDICINE
`FREE RADICAL RESEARCH COMMUNICATIONS
`FUNDAMENTAL AND APPLIED TOXICOLOGY
`GASTROENTEROLOGY
`GENE
`GENOMICS
`HEPATOLOGY
`IMMUNOPHARMACOLOGY
`INORGANIC CI IEMISTRY
`t)F Bit)CHEMISI'l(Y AND CI":I,I.Bl()I,C)GY
`JN'I'El(NA'I'IONAI,J()UI(NAI.
`IN VITRO MOLECULAR TOXICOLOGY
`IUBMB LIFE
`JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
`JOURNAL OF BIOLOGICAL CHEMISTRY
`JOURNAL OF BIOCHEMICAL TOXICOLOGY
`JOURNAL OF BIOMOLECULAR SCREENING
`JOURNAL OF CELLULAR BIOCHEMISTRY
`JOURNAL OF CHROMATOGRAPHY
`JOURNAL OF INORGANIC BIOCHEMISTRY
`JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS
`JOURNAL OF LIPID RESEARCH
`JOURNAL OF MASS SPECTROMETRY
`JOURNAL OF MEDICINAL CHEMISTRY
`JOURNAL OI'OLECULAR BIOLOGY
`JOURNAL OF MOLECULAR RECOGNITION
`JOURNAL OF NEUROCHEMISTRY
`JOURNAL OF ORGANIC CHEMISTRY
`JOURNAL OF EXPERIMENTAL BIOLOGY AND THERAPEUTICS
`JOURNAL OF PHARMACEUTICAL SCIENCES
`JOURNAL OF PHARMACY AND PHARMACOLOGY
`JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
`
`10
`
`Confidential
`
`VNDA 02699344
`
`Vanda Exhibit 2002 - Page 10
`
`
`
`JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
`JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
`JOURNAL OF THE NATIONAL CANCER INSTITUTE
`LIFE SCIENCES
`L I I'I I )S
`LIVER
`METABOLISM
`MOLECULAR BRAIN RESEARCH
`MOLECULAR CARCINOGENESIS
`MOLECULAR AND CELLULAR PROTEOMICS
`MOLECULAR 1NTERVENTIONS
`MOLECULAR PHARMACEUTICS
`MOLECULAR PHARMACOLGY
`MOLECULAR TOXICOLOGY
`MUTAGENESIS
`MUTATION RESEARCH
`NATURE
`NA'I'Ul<E Bit)I'VCHN()I.C)GY
`NATURE CHEMICAL BIOLOGY
`NATURE COMMUNICATIONS
`NATURE MEDICINE
`NATURE STRUCTURAL BIOLOGY
`NEW ENGLAND JOURNAL OF MEDICINE
`NUCLEIC ACIDS RESEARCH
`NUCLEOSIDES AND N UCLEOTIDES
`NUTRITION AND CANCER
`ONCOLOGY RESEARCH
`PEPTIDE AND PROTEIN LETTERS
`PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY
`PI IARMACOGENETICS
`PH A I<MAC() I.(X'ICA I. REVIEWS
`PHARMACOLOGY AND THERAPEUTICS
`PHARMACOLOGY AND TOXICOLOGY
`PHYSIOLOGICAL REVIEWS
`PROCEEDINGS OF THE NATIONAL ACADEMY
`PSYCHOPHARMACOLOGY
`RESEARCH COMMUNICATIONS IN CHEMICAL
`RISK ASSESSMENT
`SCIENCE
`TOXICOLOGICAL SCIENCES
`TOXICOLOGY AND APPLIED PHARMACOLOGY
`TOXICOLOGY IN VITRO
`TOXICOLOGY LETTERS
`TRENDS IN GENETICS
`TRENDS IN MOLECULAR MEDICINE
`TRENDS IN PHARMACOLOGICAL SCIENCES
`XENOBIOTICA
`
`OF SCIENCES U.S.A.
`
`PATHOLOGY AND PHARMACOLOGY
`
`Confidential
`
`VNDA 02699345
`
`Vanda Exhibit 2002 - Page 11
`
`
`
`Other Consultant
`
`and Special Review Group Participation
`
`January, 1981
`
`February, 1981
`
`April, 1981
`
`Program Project, North Carolina State University, Raleigh (NIH)
`
`Program Project, American Health Foundation, Valhalla, N.Y. (NIH)
`
`Program Project, New York University
`
`(NIH)
`
`September, 1981
`
`Program Project, University of Vermont
`
`(NIH)
`
`1.
`
`2.
`
`3.
`
`4.
`
`5.
`
`6.
`
`7.
`
`8.
`
`9.
`
`April, 1982
`
`June, 1982
`
`May, 1983
`
`December, 1983
`
`February, 1984
`
`10.
`
`11.
`
`12.
`
`13.
`
`April, 1984
`
`June, 1984
`
`September, 1984
`
`April, 1985
`
`14.
`
`May, 1985
`
`15.
`
`February, 1986
`
`16.
`
`1986, 2007
`
`17.
`
`March, 1986
`
`Environmental Health Sciences Center, Oregon State University, Corvallis
`(Chairman, Center-initiated
`review)
`
`Basic Sciences Review Board, Veterans Administration
`and Agent Blue Research Program
`
`Special Agent Orange
`
`Environmental Health Sciences Center, Oregon State University, Corvallis
`(Chairman, Center-initiated
`review)
`
`Toxicology Training Program, University of Cincinnati
`review)
`
`(University-initiated
`
`Environmental Health Sciences Center, Oregon State University, Corvallis
`(Chairman, Center-initiated
`review)
`
`Program Project, Baylor College of Medicine (NIH)
`
`Center Grant, University of California, San Francisco (NIH)
`
`(Three Grants) Eppley Institute, Omaha (NIH) (Chairman)
`
`Toxicology Training Program, University of Cincinnati
`University-initiated
`review)
`
`(Chairman,
`
`NIH Special Study Section, NCI RFP "Innovative Approaches
`of Cancer Chemopreventive Agents"
`Development
`
`to
`
`Environmental Health Sciences Center, Oregon State University, Corvallis
`(Chairman, Center-initiated
`review)
`
`Training Program in 'I'oxicology, University of Wisconsin, Madison
`(Chairman, University-initiated
`review)
`
`NIH Special Study Section, NCI, RFA 85-CA-06, Development, Validation,
`and Application of Biochemical Markers of Human Exposure for Use in
`Epidemiological Studies
`
`Advisory Committee, Chemical
`
`Industry Institute for Toxicology
`
`NIH Physical Biochemistry Study Section, ad hoc reviewer
`
`Safety Assessment Advisory Committee, Merck, Sharp, and Dohme Research
`Laboratories
`
`June, 1986
`
`June, 1986
`
`1986-1991
`
`18.
`
`19.
`
`20.
`
`21.
`
`22.
`
`November, 1986
`
`December, 1986
`
`Program Project, Albert Einstein School of Medicine (NIH)
`
`Special Review Committee
`
`(NIH) (Chairman,
`
`Individual
`
`grant)
`
`12
`
`Confidential
`
`VNDA 02699346
`
`Vanda Exhibit 2002 - Page 12
`
`
`
`23.
`
`1986, 1990
`
`24.
`
`June, 1987
`
`25.
`
`26.
`
`27.
`
`28.
`
`29.
`
`30.
`
`31.
`
`32.
`
`33.
`
`34.
`
`35.
`
`October, 1987
`
`November, 1987
`
`November, 1987
`
`1987-1990
`
`April, 1988
`
`April, 1988
`
`June, 1988
`
`June, 1988
`
`November, 1988
`
`February, 1989
`
`June, 1989
`
`36.
`
`1989
`
`37.
`
`November, 1989
`
`38.
`
`39.
`
`40.
`
`41.
`
`42.
`
`43.
`
`44.
`
`March, 1990
`
`September, 1990
`
`October, 1990
`
`February, 1991
`
`June, 1991
`
`March, 1992
`
`March, 1993
`
`45.
`
`April, 1993
`
`46.
`
`47.
`
`May, 1993
`
`1993 -1996
`
`Technical Advisory Panel on Acrylonitrile, Chemical
`Toxicology
`
`Industry Institute for
`
`Program Project, McArdle Laboratory, University of Wisconsin, Madison
`(NIH)
`
`Program Project, Oregon State University
`
`(NIH)
`
`Technical Advisory Panel, Chemical
`
`Industry Institute for Toxicology
`
`Clinical Pharmacology Branch, National Cancer Institute (Intramural)
`
`Outstanding
`
`Investigator Award Applications, National Cancer Institute
`
`Program Project, Illinois Institute of Technology (NIH) (Chairman)
`
`Ohio Board of Regents, Eminent Scholar Program
`
`Advisory Committee, Chemical
`
`Industry Institute for Toxicology
`
`Center and Training Grants, Oregon State University
`
`(NIH)
`
`Program Project, University of Texas, Galveston (NIH) (Chairman)
`
`Program Project, Rutgers University
`
`(NIH)
`
`Program Project, State University of New York, Stony Brook (NIH)
`(Chairman)
`
`External Oversight Group, Training Program in Environmental Health
`Sciences, Harvard School of Public Health
`
`Clinical Lung Cancer Research Project, National Cancer Institute
`(Intramural)
`
`Program Project, Johns Hopkins University
`
`(NIH) (Chairman)
`
`Training Program in Toxicology, University of Wisconsin, Madison
`(Chairman, University-initiated
`review)
`
`Program Project, Harvard School of Public Health (NIH)
`
`Program Project, Duke University Marine Center
`
`(NIH)
`
`Program Project, University of Colorado (NIH)
`
`Program Project, McArdle Laboratory, University of Wisconsin (NIH)
`
`NIH Special Study Section, NIH RFA CA/ES 92-23 "Biotechnology Transfer
`to Epidemilogic Studies in Cancer"
`
`Program Project Review, Marine/Freshwater
`Oregon State University
`(University-initiated
`
`Biomedical Sciences Center,
`review)
`
`Scientific Advisory Panel, Department of Drug Metabolism, Sandoz
`
`Scientific Advisory Board, Butadiene Research Panel, Chemical
`Manufacturers'ssociation
`
`13
`
`Confidential
`
`VNDA 02699347
`
`Vanda Exhibit 2002 - Page 13
`
`
`
`48.
`
`July, 1993
`
`49.
`
`1993
`
`50.
`
`1993
`
`51.
`
`52.
`
`November, 1993
`
`November, 1993
`
`53.
`
`January, 1994
`
`NIH Special Study Section, NIH RFA CA/ES-93-24 "Environmental Factors
`and Breast Cancer in High Risk Areas"
`
`Advisory Board, NIEHS Center Developmental Grant, University of
`Louisville
`
`Advisory Board, Application for NIEHS Center Developmental Grant,
`University of North Carolina
`
`NIH Special Study Section, NIEHS Center Developmental Grant applications
`
`NIH Special Study Section, NCI Outstanding
`applications
`
`Investigator Award
`
`Study Section, American Cancer Society (Advisory Committee on Personnel
`for Research, C)
`
`February, 1994
`
`U.S. Army Breast Cancer Rcscarch Program (handled by BioRcvicw, Inc.)
`
`1994-2000, 2002-2004
`
`Board of Scientific Advisors, Schering-Plough D