`
`2016
`
`Tulane University Health Sciences Center
`Department of Urology
`1430 Tulane A venue, SL-42
`New Orleans, LA 70112-2632
`Telephone: (504) 988-5372- Fax: (504) 988-5059
`E-mail: whcllst@.tulanc.edu
`
`EDUCATION
`5/ 1/72-6/30/77
`9/ 1/77-5/1/81
`1981-1982
`
`1982-1983
`
`1983-1985
`1985-1986
`1986-1988
`
`CERTIFICATION
`G49763, ] 983
`AH3077193, 1983
`1986
`Re-Certiflcatioll, 2006
`07721 R, 1988
`1990
`1996
`
`B.SC. Physiology, McGill University, Montreal, P.Q. Canada
`M.D.C.M. McGill Medical School, Montreal, P.Q. Canada
`Internship: General Surgery, Montreal General and Royal
`Victoria Hospital, McGill University, Montreal, P.Q. Canada
`Residencv: General Surgery, Montreal General and Royal
`Victoria Hospital, McGill University, Montreal, P.Q. Canada
`Urology, University of California, San Francisco, California
`Chief Resident, Urology, University of California, San Francisco
`Fellowship: Andrology, University of California, Davis,
`California
`
`Board of Medical Examiners, State of California
`Drug Enforcement Administrative Reg
`Certification for Lithotripsy, AUA(UCSF)
`Certification for American Board of Urology
`Louisiana State Board of Medical Examiners Cert
`Fellow of the American College of Surgeons
`ESWL!Medstone Training Certificate
`
`1992-1999
`
`1989-1998
`
`ACADEMIC POSITIONS HELD
`1999-present
`Professor of Urology, Tulane University School of Medicine,
`New Orleans, Louisiana
`Associate Professor, Tulane University School of Medicine,
`New Orleans, Louisiana
`Research Affiliate, Delta Regional Primate Research Center,
`Covington, Louisiana
`Chief, Section of Urology, Charity Hospital of New Orleans,
`New Orleans, Louisiana
`Assistant Professor, Tulane University School of Medicine, New
`Orleans, Louisiana
`Instructor, Department of Urology, University of California,
`
`1989-2005
`
`1988-1992
`
`1986-1988
`
`INTELGENX 1006, pg. 1
`
`
`
`Davis, California
`
`CURRENT HOSPITAL AFFILIATIONS
`
`o Tulane University Hospital, New Orleans, Louisiana
`o Tulane- Lakeside Hospital, Metairie, LA
`o University Medical Center, New Orleans, LA
`o Veterans Administration Medical Center, New Orleans, LA
`
`RESEARCH INTERESTS
`
`o Male infertility
`o Erectile dysfunction
`o Sperm stimulation protocols for improving motion parameters ofsperm
`o Development of new pharmacological vasoactive erection drugs in animal models
`o Peyronie's disease-both basic research and clinical studies
`o Penile rehabilitation post-prostatectomy
`o Gene therapy in the treatment of erectile dysfunction
`
`HONORS, AWARDS AND FELLOWSHIPS
`
`o University Scholar, McGill University, 1976, 1977, 1978
`o Athlete ofthe Year, McGill University, (Faculty of Medicine) 1979
`o Miley B. Wesson Resident's Essay Contest, Western Section of AUA (Second Prize)
`1984
`o Northern California Resident's Seminar (Second Prize) 1985
`o
`James McCarthy Essay Contest, Western Section of AUA (First Prize, co-author) 1986
`o Poster Section, Western Section of AUA, (First Prize, co-author) 1986
`o Fellow, Urology (Infertility), University ofCalifornia, Davis (AUA Scholar) 1986, 1987,
`1988
`o Miley B. Wesson Resident's Essay Contest, Western Section of AUA (Honorable
`Mention) 1987
`o Dean's Research Award for "The Assessment of Fertility Potential in Male Paraplegics."
`University of California, Davis ( 1987)
`James McCarthy Essay Contest, Western Section of AUA (Second Prize) 1988
`o
`o American Urological Association, First Prize for Clinical Research ( 1988)
`o Resident Presentation Contest (Co-Author), "A Modified Approach to Arterialization of
`the Dorsal Vein ofthe Penis in Vasculogenic Impotence." (1989)
`o Southeast Section American Urological Association, First Place in the T. Leon Howard
`Pyelogram Conference, (Co-author), "Renal Malakoplakia" (1990)
`o Round Table Contest, Second Prize, Western Section of AUA (1990)
`o Prize Poster, American Fertility Society: "Absence of Short Term Gonadotoxicity in
`Primate Testes Receiving Shock Wave Therapy" 1990.
`o Prize Poster, Vth International Congress of Andrology ("Role of Platelet Activating
`Factor (PAF) and Pentoxifylline (PTX) as Human Sperm Cryoprotectants") 1993.
`o Prize Paper, Southern Medical Association Annual Assembly, (Prophylaxis in Penile
`Prosthetic Surgery) co-author. (1993)
`o Young Andrologist Award, American Society of Andrology (1994)
`o Prize Paper, Southern Medical Association Annual Assembly, (Stimulation of Collagen
`
`INTELGENX 1006, pg. 2
`
`
`
`Wayne JG Hellstrom, MD, FACS I January
`
`2016
`
`Production in an In-Vitro Model for Peyronie's Disease) co-author. (1994)
`o Research Mentor for Ben Shenassat recipient of the "Hume Award for Excellence in
`Urological Research." ( 1995)
`o Prize Paper, Southern Medical Association Annual Assembly, "Testicular Prosthesis:
`Pitfalls in Management of the Testicular Mass and Testicular Trauma" (co-author).
`Kansas City, MO (1995)
`o Award for Medical Excellence Scholarship Program, Southern Medical Association
`Annual Assembly. Reconstruction of a Total Anterior Urethral Defect Utilizing Buccal
`Mucosa", Kansas City, MO (1995)
`o Award for best presentation on MSD (preclinical), "Gene Transfer of Endothelial Nitric
`Oxide Synthase Partially Restores NO Synthesis and Erectile Function in Streptozotocin
`Diabetic Rats", 5111 Congress of the European Society for Sexual and Impotence Research
`(ESSM), Hamburg, Gennany (2002)
`o Award for best presentation on male sexual dysfunction (clinical), "Randomized, double(cid:173)
`blind, placebo-controlled, at-home study of intranasal bremelanotide (PT-141) in men
`with
`erectile
`dysfunction
`with
`and
`without diabetes mellitus" at ESSM, Vienna, Austria, Dec 2006
`o Selected as Best Posters during Moderated Poster Session: 2008 AUA Meeting, Abstract
`# 970- Ultrastructural Changes of the Tunica Albuginea in Response To Cavernosal
`Nerve Injury In Rats
`o Tulane AOA Honor Society Induction (2013)
`o American Association of Genitourinary Surgeons (2014)
`
`PROFESSIONAL SOCIETIES
`
`o American Association of Genitourinary Surgeons (AAGUS)
`o American Society of Andrology
`o American Urological Association
`o Fellow of the American College of Surgeons
`International Society for Sexual Medicine (I SSM)
`o
`o Sexual Medicine Society ofNorth America (SMSNA)
`o Society of Urologic Prosthetic Surgery (SUPS)
`o Louisiana State Medical Society
`o Northern California Association of Urologists (1983-1988)
`o Orleans Parish Medical Society
`o Societe lnternationale d'Urologie
`o Society of Genitourinary Reconstructive Surgeons (GURS)
`o Society of Male Reproduction and Urology
`o Society of University Urologists, Inc.
`o Southeastern Section of the AUA
`o American Fertility Society/American Society for Reproductive Medicine (1986-201 0)
`o American Medical Association ( 1 988-1 994)
`o Southern Medical Association ( 1988-2005)
`
`EDITORSHIPS
`
`2015- Present
`20 13 - Present
`
`Urology (Gold Journal), Associate Editor
`Journal ofUrology, Editorial Board
`
`INTELGENX 1006, pg. 3
`
`
`
`2010 - 2015
`2009 - Present
`2008 - 2013
`20 I 0 - Present
`2007 - 2013
`2004 - 2006
`2004 - 2009
`2005 - 2015
`2002 - 2005
`1998 - 2006
`1996 - 2005
`1995 - Present
`1995 - Present
`1 993 - Present
`1993 - Present
`1992 - 1996
`1 991 - Present
`1990 - 2000
`20 14 - Present
`1988 - 2005
`
`US Urology, Editorial Board
`Annals of Urology
`International Journal of Andrology, Associate Editor
`Asian Journal of Andrology, Editorial Board Member
`Journal of Urology, Specialty Society Editor (SMSNA)
`Issues in Sexual Medicine, Section Editor
`Current Sexual Health Reports, Section Editor
`Journal of Sexual Medicine, Associate Editor
`International Journal of Impotence Research, Associate Editor
`Web Site Committee (Society for the Study of Sexual Dysfunction)
`Journal of Andrology, Associate Editor
`Biology of Reproduction (Reviewer)
`Journal ofCiinicallnvestigation (Reviewer)
`Urology (Reviewer)
`Journal ofUrology (Reviewer)
`Journal of Andrology, Editorial Board Member
`New England Journal of Medicine (Reviewer)
`Assisted Reproductive Technologies for Andrology. ARTA (Co-editor)
`Andrology (Reviewer)
`Fertility and Sterility Journal (Reviewer)
`
`EDUCATIONAL ADVISOR FOR
`
`o
`
`o Run Wang, M.D.- Fellowship (1990-1993); "Studies on the effects ofvaricocele in primates
`and humans."
`o Michelle Bell, Ph.D. Thesis (1991-1994); "Studies on membrane fluidity and sperm
`capacitation of sperm." Basic research project was undertaken in the Andrology laboratory
`at TUMC.
`o Eugene Kukuy - A.F.U.D. Summer Scholarship ( 1991 ); "The biochemical evaluation of the
`erectile response to different pharmacological agents using the cat model."
`Joseph V. Candela - A.F.U.D. Summer Scholarship ( 1992); "Penile Prosthetic Implantation:
`A comparison of the penile-scrotal and infra pubic surgical approaches."
`o Kyoko Sakamoto - A.F.U.D. Summer Scholarship ( 1992); "Usefulness of Pentoxifylline
`stimulated cryopreserved sperm for antisperm antibody binding in immunobead-rosette
`test."
`o Kathryn Elizabeth Noles - A. F. U.D. Summer Scholarship ( 1993 ); "In-vitro studies on
`collagen elaboration in the pathophysiology of Peyronie's disease."
`o Benham Ben Shenassa - A.F.U.D. Summer Scholarship (1994); "Effect of papaverine,
`phentolamine and prostaglandin E1 triple combination on nitric oxide synthase in penile
`tissue."
`o Demetrios Simopoulos- (1994); "Immunohistochemical localization of nitric oxide synthase
`in penile tissue."
`o Nikolaos Sofikitis, Ph.D. - Research Instructor (June 1994 - February 1995); "Use of the
`feline model for comparison and characterization of erectile response to different
`pharmacologic agents."
`o Hunter Clay Champion - A. F. U.D. Summer Scholarship (1995); "Investigation of
`
`INTELGENX 1006, pg. 4
`
`
`
`Wayne JG Hellstrom, MD, FACS I January
`
`2016
`
`o
`
`"Effect on
`
`adrenomedullin in the feline erection model."
`o Wesley W. Bryan -
`(1995); "Retrospective review of silastic grafts in the surgical
`management of Peyronie 's disease."
`o Lance Estrada- ( 1995); "Effect of cytokines on human sperm parameters."
`o Run Wang. M.D. - Research Fellow (1993-1997); "Studies on sperm motion and
`stimulation; pharmacological evaluation of penile erection in animal models."
`o Mariano Barcelos Filho. M.D. (April 1-May 30, 1996); Visiting physician and observer in
`Urology & Andrology.
`Javier Molina. M.D. (March 1-April 20, 1997); Visiting physician and observer in
`Andrology and Urology.
`o S. Bradley Pradel, M.D. - Research Student (June 1997 - July 1997) -
`pentoxifylline on human sperm acrosome challenge (ARIC) test."
`o Charles F. Chehardv, M.D. - Visiting Fellow (January 1998 - March 1998) - "Effect of
`spinal cord injury on rat reproductive functions."
`o Trinity J. Bivalacqua - A.F.U.D. Summer Scholarship ( 1998-pending); Graduate Student
`(May 1997 - 1998) - "The effect of phosphodiesterase inhibitors on penile erection," and
`"Cellular and molecular aspects of Peyronie's disease in a rat model."
`o Claudio Teloken. M.D. - Visiting professor and observing urologist in the Section of
`Andrology (February 1999).
`o Erik Diner, A.F.U.D. Summer Scholarship ( 1999- ); "Evaluation of erectile response and
`nitric oxide synthase isoforms in the Peyronie's disease rat model."
`o Tom Novak, A.F.U.D. Summer Scholarship ( 1999- ); "Oral and intralesional therapies for
`Peyronie's disease in a rat model."
`o Nicholas Sofikitis, Visiting research fellow, infertility research on round spermatozoa
`o Sam boon Leungwattanaki j, Visiting Fellow (September 1999- 2001)
`o
`JS Hyun and DY Yang. Visiting Research Fellows (2000-200 I)
`o Danielle Dienert, A.F.U.D. Summer Scholarship (2000); "Effects of sildenafil on vaginal
`and clitoral tissue in pre
`and post-menopausal women: an organ bath study."
`o Greg Lacy, AFUD Summer Scholarship (200 1 ); "Surgical management of Peyronie's
`disease using a rat model."
`o Dave Adams, AFUD Summer Scholarship (200 1 ); "Gene therapy for treatment of Diabetic
`Erectile Dysfunction using a rat model."
`o Mustafa Usta, Visiting Research Fellow, "Protective effect of aminoguanidine on erectile
`function in streptozotocin in diabetic rats"
`o Serap Gur, Visiting Research Post-Doc (2005-2008)
`o Muammer Kendirci, Visiting Research Fellow (2003-2005)
`o Landon Trost, Research Medical Student (2004-2007)
`o Levant Gurkhan, Visiting Research Fellow (2007-2008)
`o Fikret Erdimir. Visiting Research Fellow (2007-2008)
`o Yolanda Cockeran. Physician's Assistant (2007- 2008)
`o Liman Ma. Basic Research Fellow (20 I 0-2011)
`o Michael Pinsky, Research Medical Student (2010)
`o Ahmet Gokce. Basic Research Fellow (2011-2013)
`o Ege Can Serefoglu. Basic Research Fellow (2011-2012)
`o Neils Johnson. Research Medical Student (2011-2012)
`o Erhan Ates. Clinical Research Fellow (2012)
`o Landon Trost, Clinical Research Fellow (20 12-2013)
`o Ronny Tan. Clinical Andrology Fellow (2013-)
`o Premsant Sangkum, Basic Research Fellow (20 13-20 15)
`o Theodore Saitz, Research Medical Student (20 12-2013)
`
`INTELGENX 1006, pg. 5
`
`
`
`o Louis Aliperti, Research Medical Student (20 12-2013)
`o Victor Sandoval. Visiting Research Fellow (2012)
`o Caner Baran. Visiting Research Fellow (2013-2014)
`o Taylor Peak. Research Medical Student (2014-present)
`o Faysal Yafi, Clinical Fellow (2014-present)
`
`COMMITTEES: Intramural
`
`University Committees:
`1989-1993
`Member, Human Subjects Review Committee, Tulane University School of
`Medicine, New Orleans
`Member, Search Committee for Chairman of the Department of Obstetrics and
`1989-1990
`Gynecology, Tulane University School of Medicine, New Orleans
`Faculty Advisory Committee to the Dean, Tulane University School of Medicine,
`
`1990-1992
`New Orleans
`Ob-GYN In-Depth Review Subcommittee, Tulane University School of
`1994
`Medicine, New Orleans
`1996-1997
`Medicine In-Depth Review Subcommittee, Tulane University School of
`Medicine, New Orleans
`2003-2007
`Nominations Committee Member
`
`Member, Infection Control Committee, Tulane University Hospital and Clinic,
`
`Hospital Committees:
`1989
`Member, Outpatient Surgery Committee, Tulane University Hospital and Clinic,
`New Orleans
`1989-1994
`New Orleans
`Member, Executive Committee, Charity Hospital, New Orleans
`1989-1994
`Member, Quality Assurance Review Committee, Tulane University Hospital and
`1990-1994
`Clinic, New Orleans,
`1990-Present Member, Surgery Peer Review Committee, Charity Hospital, New Orleans
`1993-1994
`Member, Operating Room Committee, Tulane University Hospital and Clinic,
`New Orleans, LA
`1996-1999
`Member, Operating Room Committee, Tulane University Medical Center
`Member, Medical Staff Review Subcommittee, Tulane University Hospital and
`1990-1994
`Clinic, New Orleans
`1998
`Obstetrics and Gynecology Review Committee, Tulane University Medical
`Center
`2001
`2001
`2001-2002
`
`Performance Improvement Committee, Tulane University Medical Center
`Member, Physiology Review Subcommittee, Tulane University Medical Center
`Chair, Operating Room committee, Tulane University medical Center
`
`COMMITTEES: Extramural
`
`1992-Present
`1992-1994
`1993
`1993-1996
`1994-1996
`Society
`1994-1995
`
`Member, Long-term Planning Committee, American Society of Andrology
`Member, Student Affairs Committee, American Society of Andrology
`Member, Abstract Committee, American Fertility Society
`Secretary, Southern Medical Association
`Executive Member, Male Reproduction/Urology Committee, American Fertility
`
`Member, Education Policy Committee, American Society of Andrology
`
`INTELGENX 1006, pg. 6
`
`
`
`Wayne JG Hellstrom, MD, FACS January
`2016
`
`1995-1997
`1993-1997
`1995
`
`1995-1996
`1995-2000
`
`1996
`1996-1997
`
`1996-2000
`
`1997
`1997-1998
`1997-1999
`Medicine
`1997-2000
`1998
`1998-2001
`1998
`1999-2008
`1999-2004
`1998-2000
`2002-2010
`2002-2007
`2003-2004
`2004-2005
`2005-2010
`2006-2014
`2007-2008
`2008-2009
`2008-2012
`
`2008-2015
`
`2008-2010
`2009-2012
`2012-2014
`20 14-present
`
`Chairman, Education Policy Committee, American Society of Andrology
`Member, Industrial Relations Committee, American Society of Andrology
`Member, Auditing Committee, American Urological Association, Society for the
`Study of Male Reproduction
`Member, Impotence Guidelines Committee, American Urological Association
`Member, USP General Committee of Revision, Expert Advisory Panel on
`Urology
`Chairman, Symposium on Testosterone Deficiency, Southern Medical Assoc.
`Member, Auditing Committee, AUA Society for the Study of Impotence
`Research
`Member, American Urological Association and the American Foundation of
`Urologic Disease (AUA/AFUD) Research Committee
`Vice Chairman of Urology Section, Southern Medical Association
`Member, Auditing Committee, Society International Urologic
`Member, Strategic Plan Committee - American Society of Reproductive
`
`Representative of Liaison Committee; ASA/ASRM and ASBUR
`The New Strategic Planning Committee for the SMRU
`President, Section of Urology, Southern Medical Association
`Member, Society for the Study of Sexual Dysfunction Web Site Committee
`Member, Abstract Committee, AUA and Southeastern Section of the AUA
`Chair, Liaison Committee- ASA/ASRM and ASBUR
`Member, Awards Committee- American Society of Andrology
`Chair, Audit Committee, ISSM
`Board of Directors, Sexual Medicine Society of North America
`LA Urological Association, President
`Sexual Medicine Society ofNorth American, President
`Board Member, Coalition for the Advancement of Prosthetic Urology
`Treasurer, Society for Urologic Prosthetic Surgery
`Vice President, American Society of Andrology
`President, American Society of Andrology
`Chairman, Development Committee, Sexual Medicine Society ofNorth America
`(SMSNA)
`Present Chairman, International Consultation on Sexual Medicine
`(Section on Prosthetics)
`President- elect, Society for Urologic Prosthetic Surgery (SUPS)
`Secretary General, International Society ofSexual Medicine
`President-Elect, International Society of Sexual Medicine
`President, International Society of Sexual Medicine
`
`PUBLICATIONS IN REFERRED JOURNALS
`
`1.
`
`2.
`
`3.
`
`Hellstrom WJG, Kogan BA, Jeffrey RB and McAninch JW: The natural history of
`prenatal hydronephrosis with normal amounts of amniotic fluid. J Urology, 132:947-
`950,1984.
`Hellstrom WJG, Edwards MSB and Kogan BA: Urological aspects of the tethered cord
`syndrome. J Urology, 135:317-320,1986.
`Lue TF, Hellstrom WJG, McAninch JW and Tanagho EA: Priapism: A refined approach
`to diagnosis and treatment. J Urology, 136: I 04-1 08,1986.
`
`INTELGENX 1006, pg. 7
`
`
`
`4.
`
`5.
`
`6.
`
`7.
`
`8.
`
`9.
`
`indicate
`
`immunologic
`
`Hellstrom WJG: Subclinical genital infection and male infertility: No link found. Urology
`Times 14, 1986.
`Junemann KP, Lue TF, Abozeid M, Hellstrom WJG and Tanagho EA: Blood gas analysis
`in drug-induced penile erection. Urologia International is, 41 :207-211, 1986.
`Hellstrom WJG: In unexplained male infertility, is antibiotic treatment of real value?
`Urology Times, 14,1987.
`Hellstrom WJG, Schacter J, Sweet RL, McClure RD: Is there a role for chlamydia
`trachomatis and genital mycoplasma in male infertility? Fertility and Sterility, 48:337-
`339,1987.
`Hellstrom WJG, Schmidt RA, Lue TF and Tanagho EA: Neuromuscular dysfunction in
`non bacterial prostatitis. Urology, 30:183-8,1987.
`Hellstrom WJG, Deitch AD, deVere White RA: Clinical Applications of DNA flow
`infertility. Surgical Forum.
`in evaluating male
`cytometry of testicular aspirates
`38:642,1987.
`10. Hellstrom WJG, Overstreet JW, Moore S, Samuels S, Chang RJ, Lewis EL: Antisperm
`antibodies bind with different patterns to sperm of different men. J Urology, 138:895-
`8,1987.
`11. Hellstrom WJG: Voiding dysfunction with nonbacterial prostatitis. Medical Aspects of
`Human Sexuality, 21:36,1987.
`12. Hellstrom WJG: Serum
`immunoglobulin G antibody may
`infertility. Urology Times, 16:21,1988.
`13. Lewis EL, Hellstrom WJG: Improved design for microsurgery table. Urology, 32:452-
`3,1988.
`14. Hellstrom WJG, Overstreet JW, Samuels SJ, Lewis EL: The relationship of circulating
`antisperm antibodies to sperm surface antibodies in infertile men. J Urology, 140:1039-
`44,1988.
`15. Narayan P, Lillian D, Hellstrom WJG, Hedgcock M, Jajodia PB, Tanagho EA: The
`benefits of combining early radionuclide renal scintigraphy with routine bone scans in
`patients with prostate cancer. J Urology, 140: 1448-51, 1988.
`16. Hellstrom WJG, Deitch AD, deVere White RW: Evaluation ofvasovasostomy candidates
`by DNA flow cytometry of testicular aspirates. Fertility and Sterility, 51 :546-48,1989.
`17. Hellstrom WJG, Stone AR, Deitch AD, deVere White RW: The clinical application of
`aspiration DNA
`flow cytometry
`to neurologically
`impaired men entering an
`electroejaculation program. J Urology, 142(2 Pt 1 ):309-12, 1989.
`18. Hellstrom WJG and Sikka SC: Pentoxifylline stimulates the movement characteristics of
`cryopreserved sperm. Surgical Forum. 40:648,1989.
`19. Hellstrom WJG, Tesluk H, Deitch AD, deVere White RW: Comparison of flow cytometry
`to routine testicular biopsy in male infertility. Urology, 35:321-6,1990.
`20. Hellstrom WJG, Samuels SJ, Waits AB, Overstreet JW: A Comparison of the usefulness
`spermmar and immunobead testing for lgG antisperm antibody binding. Fertility and
`Sterility, 52: I 027-31,1990.
`21. Hellstrom WJG: Modifications in operating-table design for urologic microsurgery. Urol
`Clin N Am, 17:135-8, 1990. PMID: 2305510.
`22. Hellstrom WJG and Kaack B: Optimum testicular aspiration technique for DNA flow
`cytometric analysis of spermatogenesis in primates (Papio anubis). Fertility and Sterility.
`54:517-21,1990.
`23. Lapeyrolerie J, Avant J, Malter J, Hellstrom WJG: Standardization of fine needle
`testes using DNA flow cytometry. Surgical Forum.
`aspiration biopsy of human
`41 :682, 1990.
`
`INTELGENX 1006, pg. 8
`
`
`
`Wayne JG Hellstrom, MD, FACS January
`2016
`
`24. Sikka SC and Hellstrom WJG: Functional evaluation and motility parameters of
`Pentoxifylline-stimulated
`cryopreserved
`human
`sperm. Assisted Reproductive
`Teclmology/Andrology, I :309, 1990.
`25. Sikka SC and Hellstrom WJG: The application of Pentoxifylline in the stimulation of
`sperm motion in men undergoing electroejaculation. J Andro/ogy, 12:165-70,1991.
`26. Dean OJ, Hellstrom WJG, Krane NK: Urologic prostheses and continuous ambulatory
`peritoneal dialysis. Letter to the Editor, J Urology, 145:1279,1991.
`27. Naftulin BN, Samuels SJ, Hellstrom WJG, Lewis EL, Overstreet JW: Semen quality in
`varicocele patients is characterized by tapering sperm cells. Fertility and Sterility, 56:149-
`51,1991.
`28. Salvatore FT, Sharman GM, Hellstrom WJG: Vacuum constriction devices (VCD) and the
`clinical urologist; making an informed selection. Urology, 38:323-7,1991.
`29. Hellstrom WJG, Wang R, Sikka SC: Platelet activating factor (PAF) stimulates motion
`parameters of cryopreserved human sperm. Fertility and Sterility, 56:768-70,1991.
`30. Hurwitz G, Reimund E, Moparty KR, Hellstrom WJG: Bilateral renal parenchymal
`malakoplakia: A case report. J Urology, 14 7:115-7,1992.
`31. Walters FP, Neal DE, Rege AB, George WJ, Ricci MJ, Hellstrom WJG: Cavemosal tissue
`antibiotic levels in penile prosthesis surgery. J Urology, 147:1282-4,1992.
`32. Ask AL, Hellstrom WJ, Norrman S, Ogren SO, Ross SB: Selective inhibition of the A
`form of monamine oxidase by 4-dimethylamino-alpha-methylphenylalkylamine derivative
`in the rat. Neuropharmacology. 21 :299-308,1982
`33. Bell M, Sikka SC, Rajasekaran M, Hellstrom WJG: Time course study of hydrogen
`lipid peroxidtion of human sperm membranes. Assisted
`peroxide
`induced
`in
`the
`Reproductive Technology/Andrology, 3:144, 1992.
`34. Hellstrom WJG: New techniques in the diagnosis and treatment of male infertility and
`vasectomy reversal. Current Opinions in Urology, 2:457-462,1992.
`35. Lee B, Sikka SC, Randrup ER, Villemarette P, Baum N, Hower JF, Hellstrom WJG:
`Standardization of penile blood flow parameters in normal men using intracavemosal PGE1
`and visual sexual stimulation. J Urology, 149:49-52,1993.
`36. Rajasekaran M, Nair AGR, Hellstrom WJG, Sikka SC: Spermicidal activity of an
`antifungal saponin obtained from the tropical herb Mollugo Pentaphylla. Contraception,
`47:401-12,1993.
`37. Hellstrom WJG, Kaack MB, Harrison RM, Thomas R, Neal DE: Absence of long-term
`shock-wave application. J
`in primates
`receiving extracorporeal
`gonadotoxicity
`Endouro/ogy, 7:17-21,1993.
`38. Daroca PJ Jr., Martin AA, Reed RJ, Krengel SS, Hellstrom WJG: Urethral nephrogenic
`adenoma. J Urologic Pathology, I: 157-72,1993.
`39. Weintraub MP, De Mouy E, Hellstrom WJG: Newer modalities in the diagnosis and
`treatment of ejaculatory duct obstruction. J Urology, 150:4, J 150-54, 1993.
`40. Weintraub MP, De Mouy E, Hellstrom WJG: Newer modalities in the diagnosis and
`treatment of ejaculatory duct obstruction. J Urology, 150:4 1150-54,1993.
`41. Sikka SC, Hellstrom WJG, Naz RK: Pentoxifylline: Role in management of male
`infertility and mechanisms of action. Molecular Andrology, 5:220-231,1993. Review
`Article.
`42. Bell M, Wang R, Hellstrom WJG, Sikka SC: Effect of cryoprotective additives and
`cryopreservation protocol on sperm membrane lipid peroxidation and recovery of motile
`human sperm. J Andrology 14:4 72-78,1993.
`43. Wang R, Higuera TR, Sikka SC, Minkes RK, Bellan JA, Kadowitz PJ, Domer FR,
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`INTELGENX 1006, pg. 9
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`Hellstrom WJG: Penile erections induced by vasoactive intestinal peptide and sodium
`nitroprusside. Urol Res. 21:75-8,1993.
`44. Wang R, Sikka SC, Veeraragavan K, Bell M, Hellstrom WJG: Platelet activating factor
`and pentoxifylline as human sperm cryoprotectants. Ferri/ Steril. 60:711-15,1993.
`45. Dahiya R, Sikka SC, Hellstrom WJG, Hayware SW, Narayan P, Tanagho EA, Lue TF:
`Phenotypic and cytogenetic characterization of a human corpus cavemosum cell line (OS(cid:173)
`I). Biochemistry and Molecular Biology Internationa/30:559-69, 1993.
`46. Wang R, Steele RH, Harrison RM, Hellstrom WJG: Radiologic observations of long-term
`partial left renal vein occlusion in the cynomolgus monkey. Infertility 16,1994.
`47. Sikka SC, Wang R, Kukuy EL, Walker CF, Hellstrom WJG: The detrimental effects of
`electric current on normal human sperm. J Andrology 15:145-50,1994.
`48. Wang R, Domer FR, Sikka SC, Kadowitz PJ, Hellstrom WJG: Nitric oxide mediates
`penile erection in cats J Urology 151:234-37, 1994.
`49. Hellstrom WJG, Candela JV, Neal DE Jr.: Successful preservation of potency in treatment
`of glans hyperemia following deep penile vein revascularization surgery. Inti J Impotence
`Research 6: 1-7,1994.
`50. Betker AM, Oats RD, Hellstrom WJG, et al.: Results in the United States with sperm
`micro-aspiration retrieval techniques and assisted reproductive technologies. J Urology
`151:1255-59,1994.
`51. Hellstrom WJG, Monga M, Wang R, Domer FR, Kadowitz PJ, Roberts JA: Penile
`the primate: induction with nitric-oxide donors. J Urology, 151:1723-
`erection in
`1727,1994.
`52. Hellstrom WJG, Bell M, Wang R, Sikka SC: Effect of sodium nitroprusside on sperm
`motility, viability, and I ipid peroxidation. Fer til Steril. 61:1117-22,1994.
`53. Wang R, Bell M, Hellstrom WJG, Sikka SC: Post-thaw motility, cAMP concentration and
`membrane lipid peroxidation after stimulation with pentoxifylline and platelet-activating
`factor. Inti J Androl. 17:169-73,1994.
`54. Monga M, Wang R, Roberts JA, Hellstrom WJG: Tunica vaginalis sperm reservoir in a
`monkey model of vas deferens obstruction. J Androl. 15:309-10, 1994.
`55. Rajasekaran M, Hellstrom WJG, Sparks RL, Sikka SC: Sperm damaging effects of
`electric current: possible role of free radicals. Reproductive Toxicology, 8:427-32, 1994.
`56. Sikka SC, Wang R, Kukuy E, Walker CF, Hellstrom WJG: The detrimental effect of
`electric current on normal human sperm. J Androl. 15:145-50,1994.
`57. Sofikitis NV, Miyagawa I, Agapitos E, Pasyianos P, Toda T, Hellstrom WJG, Kawamura
`H: Reproductive capacity of the nucleus of the male gamete after completion of meiosis. J
`Assisted Reproduction and Genetics 11:335-41, 1994.
`58. Monga M, Moreno T, Hellstrom WJG: Gunshot wounds to the male genitalia:
`management for the clinical urologist. Contemporary Urology 7:58-63, 1995.
`59. Monga M, Moreno T, Hellstrom WJG: Gunshot wounds to the male genitalia. Review. J
`Trauma 38:855-8, 1995.
`60. Monga M, Puyau FA, Hellstrom WJG: Posttraumatic high-flow internal pudendal artery(cid:173)
`urethral fistula. J Urology 153(3 Pt I ):734-6, 1995.
`61. Steele RH, Martin AA, Sikka SC, Hellstrom WJG: Penile intracavernosal substance
`abuse. Urology 45:686-88, 1995.
`62. Rajasekaran M, Hellstrom WJG, Naz RK, Sikka SC: Oxidative stress and interleukins in
`seminal plasma during leukocytospermia. Fertil Steril. 64:166-71, 1995.
`63. deBoisblanc MW, Robichaux WH, Hellstrom WJG: Large scrotal epidermal inclusion
`cyst and hydrocele. J La State Med Soc. 14 7:280-1,1995.
`64. Hellstrom WJG, Monga M, Sofikitis N: Current medical treatment of idiopathic
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`INTELGENX 1006, pg. 10
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`Wayne JG Hellstrom, MD, FACS I January
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`2016
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`oligozoospermia. Jpn J Fertil Steril. 40:386-97, 1995.
`65. Sotikitis N, Miyagawa I, Dimitriadis D, Zavos P, Sikka SC, Hellstrom WJG: Effects of
`smoking on testicular function, semen quality, and sperm fertilizing capacity. J Urology
`154: I 030-34, 1995.
`66. Lowentritt JE, Kawahara K, Human LG, Hellstrom WJG, Domingue GJ: Bacterial
`infection in prostatodynia. J Urology 154:1378-81,1995.
`67. Sikka SC, Rajasekaran M, Hellstrom WJ: Role of oxidative stress and antioxidants in male
`infertility. J Androl. 16:464-81,1995. PMID: 8867595
`68. Hellstrom WJG, Lewis R, Narayan P: Benign prostatic hyperplasia patient evaluation and
`treatment options. South Med J 5:7-8, 1996
`69. Candella JV and Hellstrom WJG: Three-piece inflatable penis prosthesis implantation: a
`comparison of the penoscrotal and infrapubic surgical approaches. J La State Med Soc.
`148:296-301,1996. PMID: 8816024
`70. Monga M and Hellstrom WJG: Medical Treatment for Male Infertility. Contemporary
`Urology 8:23-47,1996.
`71. Monga M, Broderick GA, Hellstrom WJG: Priapism in sickle cell disease: the case for
`early implantation of the penile prosthesis. Eur Urology 30:54-9,1996.
`72. Hellstrom WJG, Monga M, Cote D, Harmon E: Reconstruction of a total anterior urethral
`defect using buccal mucosa. South Med J. 89: I 088-91,1996.
`73. Hellstrom WJG, Bennett AH, Gesundheit N, Kaiser FE, Lue TF, Padma-Nathan H,
`Peterson CA, Tam PY, Todd LK, Varady JC and Place VA: A double-blind, placebo(cid:173)
`controlled evaluation of the erectile response to transurethral alprostadil. Urology 48:851-
`56,1996.
`74. Rajasekaran M, Hellstrom W, Sikka S: Quantitative assessment of cytokines (GRO alpha
`and IL-l 0) in human seminal plasma during genitourinary inflammation. Am J Reprod
`Immzmol. 36:90-5,1996.
`75. Monga M, Hellstrom WJ: Testicular Trauma. Ado/esc Med. 7:141-148, 1996. PMID:
`10359963
`76. Monga M, Sofikitis N, Hellstrom WJ: Benign Scrotal Masses in the Adolescent Male:
`Varicoceles, Spermatoceles, and Hydroceles. Ado/esc. Med. 7:131-140, 1996. PMID:
`10359962
`77. VandenBerg TL and Hellstrom WJG: Individualizing androgen replacement therapy.
`Contemporary Urology Supplement, 25-38,1997.
`78. Padma-Nathan H, Hellstrom WJG, Kaiser FE, Labasky RF, Lue TF, Nolten WE,
`Norwood PC, Peterson CA, Shabsigh R, Tam PY, Place VA and Gesundheit N: Treatment
`of men with erectile dysfunction with transurethral alprostadil. Medicated urethral system
`for erection (MUSE) study group. N Eng/ J Med. 336:1-7, 1997.
`79. Ghoniem GM, Shoukry MS, Faced AAS, Hellstrom WJG and Sakr MA: Human vasal
`changes after vasectomy: In vitro studies. Eur Urology 31 :231-36,1997.
`80. Champion HC, Wang R, Shenassa BB, Murphy WA, Coy DH, Hellstrom WJG, Kadowitz
`PJ: Adrenomedullin induces penile erection in the cat. Eur J Pharmacal. 319:71-5,1997.
`81. Wood JC, Monga M and Hellstrom WJG: Penile Calciphylaxis. Urology 50:622-4,1997.
`82. Labadie P and Hellstrom WJG: Hematospermia: Clinical directives. South Med J.
`90:S127, 1997.
`83. Champion HC, Wang R, Santiago JA, Murphy WA, Coy DH, Kadowitz PJ and Hellstrom
`WJG: Comparison of responses to adrenomedullin and calcitonin gene-related peptide in
`the feline erection model. J Andrology 18:513-21,1997.
`84. Champion HC, Wang R, Hellstrom WJ and Kadowitz PJ: Nociceptin, a novel endogenous
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`INTELGENX 1006, pg. 11
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`ligand for the ORL 1 receptor, has potent erectile activity in the cat. Am J Physiol. 273(1 Pt.
`l):E214-19, 1997.
`85. Estrada LS, Champion HC, Wang R, Rajasekaran M, Hellstrom WJ, Aggarwl, Sikka SC:
`Effect of tumor necrosis factor-alpha (TNF-alpha) and interferon-gamma (IFN-gamma) on
`human sperm motility, viability and motion parameters. lnt J And