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`Arthritis Treatment > Medications > Types of Drugs > Disease-modifying Drugs > Drug Guide: DMARDs
`
`Drug Guide: DMARDs
`Disease-modifying antirheumatic drugs stop or slow the disease
`progress.
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`ARTICLE
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`COMMENTS
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`What do they do?
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`Each disease-modifying antirheumatic drug (DMARD) works in different ways to
`slow or stop the inflammatory process that can damage the joints and internal
`organs.
`
`Who are they for?
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`Doctors prescribe DMARDs for people with inflammatory arthritis who are at risk
`of permanent joint damage. Most of the DMARDS in this guide are approved for
`rheumatoid arthritis. Some are also approved for ankylosing spondylitis, psoriatic
`arthritis, juvenile inflammatory arthritis and lupus. Some DMARDs – for example,
`cyclophosphamide and mycophenolate mofetil (CellCept) – are reserved for
`people with diseases that have the potential to cause severe organ damage, such
`as lupus or vasculitis.
`
`What’s important to know about the drug class?
`
`DMARDs, particularly methotrexate, are often prescribed with other DMARDs or
`biologics. This is called combination therapy. While DMARDs can be effective in
`slowing or modifying the disease process, they do not work quickly. You will need
`to take them consistently for weeks or even months before you notice their
`beneficial effects. Your doctor may prescribe an NSAID and/or corticosteroid with
`a DMARD, at least initially until the DMARD takes effect.
`
`Before taking DMARDs (and any medication), always tell your doctor if you have
`an active infection, high blood pressure or a history of kidney or liver disease.
`Also talk to your doctor before getting any vaccines.
`
`While taking DMARDs, it is important to be aware of any signs of infection –
`chills, fever, sore throat, painful urination, for example – and report them to your
`doctor immediately.
`
`See all DMARD drugs.
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`http://www.arthritistoday.org/arthritis-treatment/medications/types-of-drugs/disease-modifying-drugs/drug-guide-dmards.php[11/18/14 12:22:06 PM]
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`Medac Exhibit 2067
`Frontier Therapeutics v. Medac
`IPR2016-00649
`Page 00001
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`DMARDs | Disease-modifying antirheumatic drugs | Arthritis Today Drug Guide
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