`From: Meese
`
`Cc: Grote;Moenkemoel1er;Trensiok;Cawello Anette
`Bcc:
`
`Subject: re: Probe AC—8273.H
`Attachment:
`Date: 31.08.99 16:19
`
`Das hfirt sich sehr gut an!
`Danke ffir die Info,
`mfG
`COM
`
`Original text
`From Arth@SchwarzPharma, on 31.08.99 16:09:
`Wir haben uns die Probe auf dem Heiztischmikroskop betrachtet.
`Die Substanz zeigt im polarisierten Licht teilweise kristallinen Charakter.
`Der Schmelzpunkt betragt 90°—91°C; die Substanz schmilzt klar durch und
`zersetzt sich nicht.
`
`Ich denke, dies sind eher gute Nachrichten.
`Die DSC—Analytik hierzu wird morgen durchgeffihrt. Die Analyse auf chemische
`Reinheit sowie eine Quantifizierung gegen externen Standard zur Bestimmung
`3 molaren Verhéltnisses im vorliegenden Salz wird voraussichtlich morgen
`abgeschlossen sein.
`
`Wir warden fiber die Ergebnisse informieren.
`
`Grufi Arth
`
`RESTRICTED CONFIDENTIAL — SUBJECT TO PROTECTIVE ORDER
`
`_
`
`C462
`
`UCBOOBOSSS4
`
`Patent Owner, UCB Pharma GmbH — Exhibit 2101 - 0001
`
`
`
`To: Arth
`From: Meese
`Cc: Grote;Moenkemoe11er;Trensiok;Cawe11o Anette
`Bcc:
`
`Subject: re: Probe AC»82?3.H
`Attachment :
`Date :08/31/99 4:19 PM
`
`That sounds good!
`Thanks for the info,
`
`mfg
`COM
`
`Original text
`From Arth@SchwarzPharma, on 08/31/99 4:09 PM
`We have observed the sample on a hot bench microscope.
`ln polarized light. the substance shows partly crystalline character.
`The melting point is 90 0 C to 91 0 C; the substance melts completely and clear and does not decompose.
`1 think, this is rather good news.
`The DSC analysis for this will be done tomorrow. The analysis for chemical purity as well as
`quantification against external standard for the determination of the molar ratio of the present salt will
`most likely be completed tomorrow.
`
`We will inform you regarding the results
`
`Regards
`Arth
`
`
`
`Patent Owner, UCB Pharrna GmbH — Exhibit 2101'- 0002
`
`
`
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`
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`
`December 30, 2014
`
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`Patent Owner, UCB Pharma GmbH — Exhibit 2101 - 0003
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