throbber
CURRICULUM VITAE
`
`Daniel W. Armstrong
`Robert A. Welch Professor
`
`
`
`
`
`University of Texas at Arlington
`Arlington, Texas 76019
`
`LOWER DRUG PRICES FOR CONSUMERS, LLC
`Exhibit 1051-1
`IPR2016-00379
`
`

`
`DANIEL WAYNE ARMSTRONG
`
`November 2, 1949
`
`
`Fort Wayne, Indiana
`
`
`United States of America
`
`
`Married: Wife, Linda M. Armstrong; Children: Lincoln Thomas (b. 1976), Ross
`Alexander (b. 1978), Colleen Victoria (b. 1986)
`
`September 1968 - June 1972
`Washington & Lee University, Lexington, Virginia
`B.S. Interdepartmental Science and Math
`
`September 1972 - September 1974
`Texas A&M University, College Station, Texas
`M.S., Oceanography
`
`January 1975 - December 1977
`Texas A&M University, College Station, Texas
`Ph.D., Bio-organic Chemistry
`
`
`
`Date of Birth:
`
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`Place of Birth:
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`Citizen of:
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`Family Status:
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`Educational Background:
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`
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`Assistant Professor of Chemistry, Bowdoin College, Georgetown University.
`
`Associate Professor of Chemistry, Texas Tech University.
`
`Professor of Chemistry and Head of Analytical Division, Texas Tech University.
`
`Professor of Chemistry and Head of Bio-analytical Division, University of Missouri-Rolla.
`
`Curators' Distinguished Professor of Chemistry.
`
`Founder and First Director of the Center for Environmental Science and Technology, University
`of Missouri-Rolla.
`
`
`Caldwell Distinguished Professor, Iowa State University, DOE Ames Laboratory.
`2000 - 2005,
`
`
`2006 - Present Robert A. Welch Professor, Department of Chemistry/Biochemistry, University of Texas at
`Arlington.
`
`2
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`Positions:
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`1978 - 1982,
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`1983 - 1985,
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`1986 - 1987,
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`1987 - 1989,
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`1989 - 2000,
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`1991 - 1998
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`LOWER DRUG PRICES FOR CONSUMERS, LLC
`Exhibit 1051-2
`IPR2016-00379
`
`

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`Awards and Citations:
`
`Elected as a member of the Chemistry Honor Society, Phi Lambda Upsilon (PLU), 1975, Texas A&M University;
`Who's Who, Who's Who in the South and Southwest, Personalities of America, Personalities of the South,
`American Men and Women of Science, Directory of World Researchers, Who's Who in the Midwest. Teaching
`Excellence Award from the "Arts and Sciences Council" of Texas Tech University, 1985. Faculty Excellence
`Award, University of Missouri-Rolla, 1988. Teaching Excellence Award, University of Missouri-Rolla, 1988-89,
`92, and 94. Curators' Distinguished Professorship, 1989. EAS Award for Outstanding Achievements in the
`Fields of Chromatography, 1990. 1991 Great Britain’s Martin Medal in recognition of outstanding contributions
`to Chromatography. 1992 ISCO Lectureship Award for Significant Contributions to Instrumentation for
`Biochemical Separations. 1993 49th American Chemical Society Midwest Regional Award. 1993 Presidential
`Award for Research and Creativity. Publication entitled "Evaluation of the Macrocyclic Antibiotic Vancomycin as
`a Chiral Selector for Capillary Electrophoresis" received a 1994 Perkin-Elmer Award for Excellence in Capillary
`Electrophoresis. 1995 R&D 100 Award. 1995 American Association of Pharmaceutical Scientists Fellow Award.
`1996 The American Microchemical Societies’ A. A. Benedette-Pichler Award. “1997 Karen Morehouse Best
`Paper Award” presented by the 12th Annual Conference on Hazardous Waste Research. 1998 American
`Chemical Society - Helen M. Free Award for Public Outreach. 1999 American Chemical Society Award in
`Chromatography. 1999 Distinguish Scholar, Hope College/Park Davis. Caldwell Chair, Iowa State University,
`2000. Chicagoland Chromatography Discussion Group (CCDG) Merit Award, 2001. Weber Medal for
`Contributions to Pharmaceutical Science, 2001. Honorary Member of the Societatis Pharmaceuticae Slovacae,
`2001. Welch Lectureship speaker, Texas A&M University, 2002. Kenneth A.Spencer Award for Meritorious
`Contributions to Agricultural and Food Chemistry, 2002. Dow Lectureship in Chemistry, University of British
`Columbia, 2003. IAP Lectureship, Columbia University, NY 2003. Chirality Medal, Shizuoka, Japan, 2003.
`Vladimir J. Zuffa Medal for Pharmaceutical Chemistry, 2004. Dal Nogare Award for Separation Science, 2005.
`Medal of the Slovak Medical Society, 2007. Admitted as a Fellow of The Royal Society of Chemistry, 2009.
`Named American Chemical Society Fellow, 2013. UTA Distinguished Record of Research or Creative Activity
`2012. ACS Award for Separation Science & Technology, 2014. 2014 M.J.E. Golay Award. UT Arlington
`Distinguished Scholars Award 2014. Inducted to the UTA Academy of Distinguished Scholars, 2014. Named to
`the Analytical Scientist’s 2013 Power List top 20 (http://theanalyticalscientist.com/the-power-list-2013/). Wilfred
`T. Doherty Research & Service Award – DFW Section of American Chemical Society, 2015. Editor of Chirality.
`Section Editor for Amino Acids. Separations Associate Editor for Analytical Chemistry. Member of the Editorial
`Board of Journal of Pharmaceutical & Biomedical Analysis, Amino Acids Journal, The Journal of
`Chromatography, The Journal of Liquid Chromatography, The Journal of Planar Chromatography, Journal of
`Inclusion Phenomena, Separation Science and Technology, and Chromatographia. Member of the
`Instrumentation Board for Analytical Chemistry, 1990. Member of the Scientific Advisory Board for Analytical
`Chemistry, 1996 -98. 1999 Editorial Advisory Board of Chromatographia, 2001 Editorial Advisory Board for
`Electrophoresis, Chromatographia, J. Separation Science. 2008 Editorial Consultant for Scientia
`Chromatographia.
`
`
`
`Administrative Experience:
`
`
`
` 1.
`
`Chairman, Division of Bio-analytical Chemistry: (Texas Tech University 1983-87; Univ. of Missouri-Rolla
`1987-2000).
`State of Missouri-System Research Board: (Founding member, 1990, reviews, controls and disburses
`research funds for the State University System in areas of science, engineering, health sciences,
`humanities and social science. Annual budget $4.0M/year.
`Director for the Center for Environmental Science and Technology: (Founded (1990) this multidisciplinary
`research center which is one of three on the UMR campus. Budget $1.6 M. Involved contacts and
`liaisons with congress, industry and academia)
`Board of Directors: University of Missouri-Kansas City, Center for Environmental Studies.
`Corporate Board of Directors: Advanced Separations Technologies, Inc., Whippany, NJ.
`Chairman and CEO of Separations, Inc. (An independent corporation for the organization of meetings,
`short courses, consulting, etc.).
`Corporate Advisory Board: Bioanalytical Systems (BAS) Scientific, West Lafayette, IN.
` 7.
`Corporate Advisory Board: PDR Chiral, Inc., Palm Beach Gardens, FL.
` 8.
` 9. Member of Research Foundation (an independent nonprofit corporation for the support of the chemistry at
`the University of Missouri-Rolla, Budget ~$1.2M).
`
` 2.
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` 3.
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` 4.
` 5.
` 6.
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`3
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`LOWER DRUG PRICES FOR CONSUMERS, LLC
`Exhibit 1051-3
`IPR2016-00379
`
`

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`Presidential Award Advisory Board (Judges and recommends recipients for Presidential Research Award).
`Chairman of International Symposium on Chiral Discrimination, St. Louis, MO. Budget: $0.6M.
`Chairman of numerous other national and international conferences and symposia (average budget
`~$0.25M per symposium).
`Chairman of 22nd International Symposium on High Performance Liquid Phase Separations and Related
`Techniques, St. Louis, MO (The world’s largest international symposium and exhibition on separation
`science).
`NIH Metallobiochemistry Study Section (~$15-20M/session).
`14.
`NIH Physical Biochemistry Study Section (~$18-30M/session).
`15.
`NSF Review Board.
`16.
`Chairman of International Symposium on Chiral Discrimination, Orlando, FL. Budget:$ 250,000.00
`17.
`Laboratory Director, DOE - Ames National Laboratory.
`18.
`19. Member of the Seminar and Library Committee, Iowa State University, Ames, Iowa
`20. Member of the Salary Advisory Committee, Iowa State University, Ames, Iowa
`21.
`Head of the Salary Advisory Committee, Iowa State University, Ames, Iowa
`22.
`Head of the and member of the Faculty Search Committee, Iowa State University, Ames, Iowa
`23. Member of the Graduate Recruiting Committee, Iowa State University, Ames, Iowa
`24. Washington & Lee University Science Advisory Board, Lexington, VA
`25.
`Defense Tribunal, Universitat Jaume, Castellon, Spain
`26.
`International Scientific Committee, International Conference of Chirality
`
`Teaching Experience:
`
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`10.
`11.
`12.
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`13.
`
`Course
`
`
`
`10
`20
`11
`9
`2
`2
`38
`1
`48
`4
`22
`5
` 38 short courses
`
`
`Quantitative Analytical Chemistry
`Quantitative Analytical Chem. Lab.
`Instrumental Analysis
`Instrumental Analysis Lab.
`General Chemistry
`Organic Chemistry
`Undergraduate Research
`Adv. Quant. Analysis
`Graduate Research
`Colloid Chemistry
`Separations
`Special Topics in Analytical Chemistry
`Enantiomeric Separations for the Pharmaceutical
`Industry
`Ionic Liquids in Gas Chromatography
`
`Publications:
`
`1. "Interstitial Water Chemistry: Deep Sea Drilling Project, Legs 21 and 22", B. J. Presley, J. Trefrey,
`D. W. Armstrong and M. Nuzzo. Initial Reports of the Deep Sea Drilling Project, XXII, 861-864 (1974).
`
`2. "Novel Prebiotic Model Systems: Interactions of Nucleosides and Nucleotides with Aqueous Micellar Sodium
`Dodecanoate", J. Nagyvary, J. H. Harvey, F. Nome, D. W. Armstrong and J. H. Fendler. Precambrian Research, 3,
`509-516 (1976)
`
`3. "Novel Prebiotic Systems: Nucleotide Oligomerization in Surfactant Entrapped Water Pools", D. W. Armstrong, F.
`Nome, J. H. Fendler and J. Nagyvary. J. Mol. Evol., 9, 213-223 (1977).
`
`4. "Differential Partitioning of tRNAs between Micellar and Aqueous Phases: A Convenient Gel Filtration Method for
`Separation of tRNAs", D. W. Armstrong and J. H. Fender, Biochim. Biophys. Acta, 478, 2, 75-80 (1977).
`
`5. "Use of an Aqueous Micellar Medium to Improve the Spectrophotometric Determination of Cyanide Ion with 5,5'-
`Dithiobis(2-Nitrobenzoic Acid)", S. Spurlin, W. Hinze and D. W. Armstrong, Analyt. Lett., 10, 12, 977-1008 (1977).
`
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`Level
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`Semester Taught
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`Undergraduate
`Undergraduate
`Undergraduate/Graduate
`Undergraduate
`Undergraduate
`Undergraduate
`Undergraduate
`Graduate
`Graduate
`Graduate
`Graduate
`Graduate
`Post-Graduate
`
` Post-Graduate
`
` 2 short courses
`
`4
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`LOWER DRUG PRICES FOR CONSUMERS, LLC
`Exhibit 1051-4
`IPR2016-00379
`
`

`
`6. "Partitioning of Amino Acids and Nucleotides between Water and Micellar Hexadecyltrimethyl-ammonium Halides",
`D. W. Armstrong, R. Seguin and J. H. Fendler, J. Mol Evol., 10, 241-250 (1977).
`
`7. "Spontaneous Polypeptide Formation from Amino Acyl Adenylates in Surfactant Aggregates", D. W. Armstrong, R.
`Seguin, C. J. McNeal, R. D. Macfarlane and J. H. Fendler, J. Am. Chem. Soc., 100, 4605-4606 (1978).
`
`8. "Synthesis of Amino Acyl Adenylates Using the tert- Butoxycarbonyl Protecting Group", D. W. Armstrong, R.
`Seguin, M. Suburi and J. H., Fendler, J. Mol. Evol., 13, 103-113 (1979).
`
`9. "A Novel Phase Transfer Catalyst Capable of Facilitating Acid-Catalyzed and/or Electrophilic Reactions", D. W.
`Armstrong and M. Godat, J. Am. Chem. Soc., 101, 2489-2491 (1979).
`
`10. "Thin Layer Chromatographic Separation of Pesticides, Decachlorobiphenyl and Nucleosides with Micellar
`Solutions", D. W. Armstrong and R. Q. Terrill, Anal. Chem., 51, 2160-2163 (1979).
`
`11. "Use of Micelles in the TLC Separation of Polynuclear Aromatic Compounds and Amino Acids", D. W. Armstrong
`and M. McNeely, Anal. Lett., 12, A12, 1285-1291 (1979).
`
`12. "Organometallic Compounds as Phase Transfer Catalysts", D. W. Armstrong, H. Kornahrens, D. J. Carucci, B. A.
`Wohler, J. E. Kahn and J. K. Shillington, Tetrahedron Lett., 47, 4525-4526 (1979).
`
`13. "Use of an Aqueous Micellar Mobile Phase for Separation of Phenols and Polynuclear Aromatic Hydrocarbons via
`HPLC", D. W. Armstrong and S. J. Henry, J. Liq. Chromatogr., 3, 5, 657-662 (1980).
`
`14. "Thin Layer Chromatographic Separation of Substituted Benzoic Acids with Aqueous Solutions of α-
`Cyclodextrins", W. L. Hinze and D. W. Armstrong, Anal. Lett., 13, A12, 1093-1103 (1980).
`
`15. "Pseudophase Liquid Chromatography: Applications to TLC", D. W. Armstrong, J. Liq. Chromatogr., 3, 6, 895-
`900 (1980).
`
`16. "Reactions of Vitamin B12r with Polyhalogenated Hydrocarbon Peticides", M. C. M. Laranjevia, D. W. Armstrong
`and F. Nome, J. Bioorganic Chem., 9, 313-317 (1980).
`
`17. "Application of Pseudophase Liquid Chromatography (PLC): Highly Selective Mobile Phase for Present and Future
`Separations", D. W. Armstrong, American Laboratory, 13, 8, 14-20 (1981).
`
`18. "Partitioning Behavior of Solutes Eluted with Micellar Mobile Phases in Liquid Chromatography", D. W. Armstrong
`and F. Nome, Anal. Chem., 53, 11, 1662-1666 (1981).
`
`19. "Enhanced Fluorescence and Room Temperature Liquid Phosphorescence Detection in Pseudophase Liquid
`Chromatography (PLC)", D. W. Armstrong, W. L. Hinze, K. H. Bui and H. N. Singh, Anal. Lett., 14, A19, 1659-1667
`(1981).
`
`20. "A Simple Salt-Enhanced Surface Tension Technique for Detection of Trace Surfactants in Water", D. W.
`Armstrong, F. Lafrachise and D. Young, Anal. Chim. Acta, 135, 165-168 (1982).
`
`21. "Use of Micellar and Cyclodextrin Solutions in Liquid Chromatographic Separations," D. W. Armstrong, in Proc.
`Inter. Symp. Soln. Behavior Surfact., K. L. Mittel and E. J. Fendler, (Eds), Plenum Press, N. Y.. (1982) pp. 1273-1282.
`
`22. "Nonaqueous Reversed Phase Liquid Chromatographic Fractionation of Polystyrene", D. W. Armstrong and K. H.
`Bui, Anal. Chem., 54, 4, 706-708 (1982).
`
`23. "Use of Aqueous Micellar Mobile Phases in Reverse Phase TLC", D. W. Armstrong and K. H. Bui, J. Liq.
`Chromatogr., 5, 6, 1043-1050 (1982).
`
`24. "Mechanism of Enhancement of Analyte Sensitivity by Surfactants in Flame Atomic Spectrometry", H.
`Kornahrens, K. D. Cook and D. W. Armstrong, Anal. Chem., 54, 1325-1329 (1982).
`
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`5
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`LOWER DRUG PRICES FOR CONSUMERS, LLC
`Exhibit 1051-5
`IPR2016-00379
`
`

`
`25. "Chromatography of Amino Acids on Reversed Phase Thin Layer Plates", J. Sherma, B. P. Sleckman and D. W.
`Armstrong, J. Liq. Chromatogr., 6, 1, 95-108 (1983).
`
`26. Practice, Mechanism and Theory of Reversed Phase TLC Polymer Fractionation", D. W. Armstrong, K. H. Bui and
`R. E. Boehm, J. Liq. Chromatogr., 6, 1, 1-22 (1983).
`
`27. "Separation and Quantitation of Anionic, Cationic and Nonionic Surfactants by TLC", D. W. Armstrong and G. Y.
`Stine, J. Liq. Chromatogr., 6, 1, 23-33 (1983).
`
`28. "Theory of Homopolymer Fractionation and Its Application to Gradient Elution Liquid Chromatography", R. E.
`Boehm, D. E. Martire, D. W. Armstrong and K. H. Bui, Macromolecules, 16, 466-476 (1983).
`
`29. "Evaluation of Partition Coefficients to Micelles and Cyclodextrins via Planar Chromatography", D. W. Armstrong
`and G. Y. Stine, J. Am. Chem. Soc., 105, 2962-2964 (1983).
`
`30. "Evaluation and Perturbation of Micelle-Solute Interactions", D. W. Armstrong and G. Y. Stine, J. Am. Chem.
`Soc., 105, 6220-6223 (1983).
`
`31. "Selectivity in Pseudophase Liquid Chromatography", D. W. Armstrong and G. Y. Stine, Anal. Chem., 55, 14,
`2317-2320 (1983).
`
`32. "A Comparison of Polymer Separation Efficiency and Resolution by Gradient LC, GPC and TLC", K. H. Bui and D.
`W. Armstrong, J. Liq. Chromatogr., 7, 29-43 (1984).
`
`33. "Use of Reversed Phase TLC to Determine Polymer Molecular Weights and Molecular Weight Distributions", K.
`H. Bui and D. W. Armstrong, J. Liq. Chromatogr., 7, 45-48 (1984).
`
`34. "Theory of Homopolymer Fractionation in Semi-Dilute Solution Using Liquid Chromatography", R. E. Boehm, D.
`E. Martire, D. W. Armstrong and K. H. Bui, Macromolecules, 17, 400-407 (1984).
`
`35. "Evaluation of the Theory and Experimental Consequences of Gradient LC Polymer Separations", K. H. Bui, D.
`W. Armstrong and R. E. Boehm, J. Chromatogr., 288, 15-24 (1984).
`
`36. "Use of Pseudophase TLC in Teaching Laboratories", D. W. Armstrong, K. H. Bui and R. M. Barry, J. Chem. Ed.,
`61, 457-458 (1984).
`
`37. "Effect of Different Stationary Phases and Surfactant or Cyclodextrin Spray Reagents on the Fluorescence
`Densitometry of Polycyclic Aromatic Hydrocarbons and Dansylated Amino Acids", A. Alak, E. Heilweil, W. L. Hinze, H.
`Oh and D. W. Armstrong, J. Liq. Chromatogr., 7, 1273-1288 (1984).
`
`38. "Gradient Liquid Chromatographic Separation of Macromolecules: Theory and Mechanism", D. W. Armstrong
`and R. E. Boehm, J. Chromatogr. Sci., 22, 378-385 (1984).
`
`39. "Cyclodextrin Bonded Phases for the Liquid Chromatographic Separation of Optical, Geometrical and Structural
`Isomers", D. W. Armstrong and W. DeMond, J. Chromatogr. Sci., 22, 411-415 (1984).
`
`40. "Chiral Stationary Phases for High Performance Liquid Chromatographic Separation of Enantiomers", D. W.
`Armstrong, J. Liq. Chromatogr., 7, Suppl. 2, 353-376 (1984).
`
`41. "Facile Separation Enantiomers, Geometrical Isomers and Routine Compounds on Stable Cyclodextrin LC
`Bonded Phases", D W. Armstrong, A. Alak, K. H. Bui, W. DeMond, T. Ward, T. E. Riehl and W. L. Hinze, J. Inclusion
`Phenomena, 2, 533-545 (1984).
`
`42. "Liquid Chromatographic Separation of Diastereomers and Structural Isomers on Cyclodextrin-Bonded Phases",
`D. W. Armstrong, W. DeMond, A. Alak, W. L. Hinze, T. E. Riehl and K. H. Bui, Anal. Chem., 57, 234-237 (1985).
`
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`6
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`LOWER DRUG PRICES FOR CONSUMERS, LLC
`Exhibit 1051-6
`IPR2016-00379
`
`

`
`43. "Liquid Chromatographic Separation of Enantiomers Using A Chiral β-Cyclodextrin-Bonded Stationary Phase and
`Conventional Aqueous-Organic Mobile Phases", W. L. Hinze, T. E. Riehl, D. W. Armstrong, W. DeMond, A. Alak and
`T. Ward, Anal. Chem., 57, 237-242 (1985).
`
`44. "Separation of Metallocene Enantiomers by Liquid Chromatography: Chiral Recognition via Cyclodextrin Bonded
`Phases", D. W. Armstrong, W. DeMond and B. P. Czech, Anal. Chem., 57, 481-484 (1985).
`
`45. "Separation of Mycotoxins, Polycyclic Aromatic Hydrocarbons, Quinones and Heterocyclic Compounds on
`Cyclodextrin Bonded Phases: An Alternative LC Packing", D. W. Armstrong, A. Alak, W. DeMond, W. L. Hinze and T.
`E. Riehl, J. Liq. Chromatogr., 8, 261-269 (1985).
`
`46. "Synthesis and a Simple Molecular Weight Determination of Polystyrene", D. W. Armstrong, J. N. Marx, D. Kyle
`and A. Alak, J. Chem. Ed., 62, 705-706 (1985).
`
`47. "Micelles in Separations: Application and Theory", D. W. Armstrong, Sep. Purif. Methods, 14, 213-304 (1985).
`
`48. "Synthesis, Rapid Resolution and Determination of Absolute Configuration of Racemic 2,2'-Binaphthyl Crown
`Ethers and Analogues via β-Cyclodextrin Complexation", D. W. Armstrong, T. J. Ward, A. Czech, B. P. Czech and R.
`A. Bartsch, J. Org. Chem., 50, 5556-5559 (1985).
`
`49. "Liquid Chromatographic Retention Behavior of Organometallic Compounds and Ligands with Amine,
`Octadecylsilica and β-Cyclodextrin Bonded Phase Columns", C. A. Chang, H. A. Aziz, N. Melchor, K. H. Pannell and
`D. W. Armstrong, J. Chromatogr., 347, 578-582 (1985).
`
`50. "Improved Cyclodextrin Chiral Phases: A Comparison and Review", T. J. Ward and D. W. Armstrong, J. Liq.
`Chromatogr., 9, 407-423 (1986).
`
`51. "Micellar Effects on Molecular Diffusion: Theoretical and Chromatographic Considerations", D. W. Armstrong, T.
`J. Ward and A. Berthod, Anal. Chem., 58, 579-582 (1986).
`
`
`
`52. "Thin Layer Chromatographic Separation of Optical, Geometrical and Structural Isomers", A. Alak and D. W.
`Armstrong, Anal. Chem., 48, 582-584 (1986).
`
`53. "Efficient Detection and Evaluation of Cyclodextrin Inclusion Complex Formations", D. W. Armstrong, F. Nome, L.
`A. Spino and T. D. Golden, J. Am. Chem. Soc., 108, 1418-1421 (1986).
`
`54. "HPLC Separation of Substituted Phenolic Compounds with a β-Cyclodextrin Bonded Phase Column", C. A.
`Chang, Q. Wu and D. W. Armstrong, J. Chromatogr., 354, 454-458 (1986).
`
`55. "Separation of Drug Stereoisomers by the Formation of β-Cyclodextrin Inclusion Complexes", D. W. Armstrong, T.
`J. Ward, R. D. Armstrong and T. E. Beesley, Science, 232, 1132-1135 (1986).
`
`56. "Determination of Distribution and Concentration of Trihalomethanes in Aquatic Recreational and Therapeutic
`Facilities by Electron Capture G. C.", D. W. Armstrong and T. Golden, LC-GC, 4, 652-655 (1986).
`
`57. "Mechanistic Considerations on the Reversed Phase Liquid Chromatographic Separation of Proteins", R. S.
`Blanquet, K. H. Bui and D. W. Armstrong, J. Liq. Chromatogr., 9, 1933-1949 (1986).
`
`58. "Micelle-Mediated Resonance Raman Spectroscopy: A New Approach for Characterizing Low Levels of
`Luminescent Compounds", D. W. Armstrong, L. A. Spino, M. R. Ondrias and E. W. Findsen, J. Am. Chem. Soc., 108,
`5646-5647 (1986).
`
`59. "Characterization of Nanogram Levels of Metalloporphyrins with TLC-Resonance Raman Spectroscopy", D. W.
`Armstrong, L. A. Spino, M. R. Ondrias and E. W. Findsen, J. Chromatogr., 369, 227-230 (1986).
`
`60. "Effect of Crown Ether Surfactants on Flame Atomic Absorption and Flame Emission Signals of Some Monovalent
`Cations", T. J. Ward, D. W. Armstrong, B. P. Czech, F. J. Koszuk and R. A. Bartsch, Anal. Chim. Acta, 188, 301-305
`(1986).
`
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`7
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`LOWER DRUG PRICES FOR CONSUMERS, LLC
`Exhibit 1051-7
`IPR2016-00379
`
`

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`61. "Optical Isomer Separations by Liquid Chromatography", D. W. Armstrong, Anal. Chem., 59, 84A-91A (1987).
`
`62. "Use of Microcolumn Liquid Chromatography With a Chiral Stationary Phase for the Separation of Low Resolution
`Enantiomers", S. M. Han and D. W. Armstrong, J. Chromatogr., 389, 256-260 (1987).
`
`63. "Separation of Tamoxifen Geometric Isomers and Metabolites by Bonded Phase ß-Cyclodextrin Chromatography",
`R. D. Armstrong, T. J. Ward, N. Pattabiraman, C. Benz and D. W. Armstrong, J. Chromatogr., 414, 256-260 (1987).
`
`64. "Optimization of Liquid Chromatographic Separations on Cyclodextrin Bonded Phases", D. W. Armstrong and W.
`Li, Chromatogr., 2, 43-48 (1987).
`
`65. "Micelle-Mediated Resonance Raman Analysis of Dilute Solutions of Fluorescent Molecules Using Ultraviolet
`Laser Excitation", D. W. Armstrong, L. A. Spino, T. Vo-Dinh and A. Alak, Spectroscopy, 2, 54-58 (1987).
`
`66. "Resonance Raman Analysis of Fluorescent Compounds Using Micellar Solutions and Ultraviolet Laser
`Excitation", L. A. Spino, D. W. Armstrong, A. M. Alak and T. Vo-Dinh, Appl. Spectrosc., 41, 771-773 (1987).
`
`67. "Packing Induced Brittleness in Polyimide and Aluminum Clad Fused Silica Capillaries", S. M. Han and D. W.
`Armstrong, Anal. Chem., 59, 1583-1584 (1987).
`
`68. "Inexpensive, Low-Dead Volume Flow Cells for Microcolumn Liquid Chromatography", L. A. Spino, S. M. Han and
`D. W. Armstrong, J. Liq. Chromatogr., 10, 1603-1611 (1987).
`
`69. "Theoretical Study on the Use of Secondary Equilibria for the Separation of Small Solutes by Field Flow
`Fractionation", A. Berthod and D. W. Armstrong, Anal. Chem., 59, 2410-2413 (1987).
`
`70. "Enrichment of Enantiomers and Other Isomers with Aqueous Liquid Membranes Containing Cyclodextrin
`Carriers", D. W. Armstrong and H. L. Jin, Anal. Chem., 59, 2237-2241 (1987).
`
`71. "Direct Liquid Chromatographic Separation of Racemates with an α-Cyclodextrin Bonded Phase", D. W.
`Armstrong, X. F. Yang, S. M. Han and R. Menges, Anal. Chem., 59, 2594-2596 (1987).
`
`72. "Direct Synchronous Luminescence Detection of Co-Eluting Solutes in Pseudophase LC", L. A. Spino, D. W.
`Armstrong and T. Vo-Dinh, J. Chromatogr., 409, 147-154 (1987).
`
`73. "Enantiomeric Resolution of Nicotine and Nicotine Analogues by Microcolumn Liquid Chromatography with (cid:31)-
`Cyclodextrin Inclusion Complexes", D. W. Armstrong, L. A. Spino, S. M. Han, J. I. Seeman and H. V. Secor, J.
`Chromatogr., 411, 490-493 (1987).
`
`74. "Separation of Optical Isomers of Scopolamine, Atropine and Cocaine", D. W. Armstrong, S. M. Han and Y. I. Han,
`Anal. Biochem, 167, 261-264 (1987).
`
`75. "Highly Selective Protein Separations with Reversed Micellar Liquid Membranes", D. W. Armstrong and W. Li,
`Anal. Chem., 60, 86-88 (1988).
`
`76. "Theoretical Considerations Concerning the Separation of Enantiomeric Solutes by Liquid Chromatography", R. E.
`Boehm, D. E. Martire and D. W. Armstrong, Anal. Chem., 60, 522-528 (1988).
`
`77. "Centrifugal Partition Chromatography I-General Features", A. Berthod and D. W. Armstrong, J. Liq. Chromatogr.,
`11, 547-566 (1988).
`
`78. "Centrifugal Partition Chromatography II-Selectivity and Efficiency", A. Berthod and D. W. Armstrong, J. Liq.
`Chromatogr., 11, 567-583 (1988).
`
`79. "Structural Factors Affecting Chiral Recognition and Separation on β-Cyclodextrin Bonded Phases", S. M. Han, Y.
`I. Han and D. W. Armstrong, J. Chromatogr., 441, 376-381 (1988).
`
`
`
`
`8
`
`LOWER DRUG PRICES FOR CONSUMERS, LLC
`Exhibit 1051-8
`IPR2016-00379
`
`

`
`80. "Liquid Chromatographic Resolution of Enantiomers Containing Single Aromatic Rings with ß-Cyclodextrin
`Bonded Phases", D. W. Armstrong, Y. I. Han and S. M. Han, Anal. Chim. Acta, 208, 275-281 (1988).
`
`81. "Enantiomeric Separations in Chromatography", D. W. Armstrong and S. M. Han, Critical Reviews in Analytical
`Chemistry, 19, 175-224 (1988).
`
`82. "Centrifugal Partition Chromatography III-Physico Chemical Properties of Ternary Liquid Systems", A. Berthod, J.
`D. Duncan and D. W. Armstrong, J. Liq. Chromatogr., 11, 1171-1185 (1988).
`
`83. "Centrifugal Partition Chromatography IV-Preparative Sample Purification and Partition Coefficient Determination",
`A. Berthod, Y. I. Han and D. W. Armstrong, J. Liq. Chromatogr., 11, 1187-1204 (1988).
`
`84. "Centrifugal Partition Chromatography V-Octanol-Water Partition Coefficients Direct and Indirect Determination",
`A. Berthod and D. W. Armstrong, J. Liq. Chromatogr., 11, 1441-1456 (1988).
`
`85. "Centrifugal Partition Chromatography VI-Temperature Effects", A. Berthod and D. W. Armstrong, J. Liq.
`Chromatogr., 11, 1457-1474 (1988).
`
`86. "Enantiomeric Resolution and Chiral Recognition of Racemic Nicotine and Nicotine Analogues by β-Cyclodextrin
`Complexation", J. I. Seeman, H. V. Secor, D. W. Armstrong, K. D. Timmons and T. J. Ward, Anal. Chem., 60, 2120-
`2127 (1988).
`
`87. "Use of Secondary Equilibria for the Separation of Small Solutes by Field Flow Fractionation", A. Berthod, D. W.
`Armstrong, M. N. Myers and J. C. Giddings, Anal. Chem., 60, 2138-2141 (1988).
`
`88. "Planar Chromatographic Separation of Enantiomers and Diastereomers with Cyclodextrin Mobile Phase
`Additives", D. W. Armstrong, F. He and S. M. Han, J. Chromatogr., 448, 345-354 (1988).
`
`89. "Study of the Origin and Mechanism of Band Broadening and Pressure Drop in Centrifugal Counter Current
`Chromatography", D. W. Armstrong, G. L. Bertrand and A. Berthod, Anal. Chem., 60, 2513-2519 (1988).
`
`90. "Hot Thin Layer Chromatographic Fractionation of Polyethylene", D. W. Armstrong and X. F. Yang, J.
`Chromatogr., 456, 440-443 (1988).
`
`91. "Evaluation of Dye-Micelle Binding Constants Using Diffusion Sensitive Band Broadening Effects", D. W.
`Armstrong, R. Menges and S. M. Han, J. Coll. Interf. Sci., 126, 239-242 (1988).
`
`92. "Use of Hydroxypropyl- and Hydroxyethyl- Derivatized β-Cyclodextrin for the TLC Separation of Enantiomers and
`Diastereomers", D. W. Armstrong, J. R. Faulkner, Jr., and S. M. Han, J. of Chrom., 452, 323-330 (1988).
`
`93. "Separation of Cyclodextrins Using Cyclodextrin Bonded Phases", H. L. Jin, A. M. Stalcup and D. W. Armstrong, J.
`Liq.Chromatogr., 11, 3295-3304 (1988).
`
`94. "Theory and Use of Centrifugal Partition Chromatography", D. W. Armstrong, J. of Liq. Chromatogr., 11, 2433-
`2446 (1988).
`
`95. "An Evaluation of the LC Separation of Monosaccharides, Disaccharides, Trisaccharides, Tetrasaccharides and
`Sugar Alcohols with Stable Cyclodextrin Bonded Phases", D. W. Armstrong and H. L. Jin, J. Chromatogr., 462, 219-
`232 (1989).
`
` 96. "Model for Conductometric Detection of Carbohydrates and Alcohols as Complexes with Boric Acid and Borate
`Ion in High Performance Liquid Chromatography", G. L. Bertrand and D. W. Armstrong, Anal. Chem., 61, 631-632
`(1989).
`
`97. "Liquid Chromatographic Separation of Anomeric Forms of Saccharides with Cyclodextrin Bonded Phases", D. W.
`Armstrong and H. L. Jin, Chirality, 1, 27-37 (1989).
`
`
`
`
`9
`
`LOWER DRUG PRICES FOR CONSUMERS, LLC
`Exhibit 1051-9
`IPR2016-00379
`
`

`
`98. "Optical Enrichment of Dansyl-rac-Amino Acids by Formation of Crystalline Inclusion Complexes with
`Cyclodextrin", H. L. Jin, A. M. Stalcup, and D. W. Armstrong, Chirality, 1, 137-141 (1989).
`
`99. "Substitutent Effects on the Binding of Phenols to Cyclodextrins in Aqueous Solution", G. L. Bertrand, J. R.
`Faulkner, Jr., S. M. Han, and D. W. Armstrong, J. Phys. Chem., 93, 6863-6867 (1989).
`
`100. "Separation of Homologous and Isomeric Alkaloids Related to Nicotine on a β-Cyclodextrin Bonded Phase", J. I.
`Seeman, H. V. Secor, D. W. Armstrong, K. D. Timmons, and T. J. Ward, J. Chromatogr., 483, 169-177 (1989).
`
`101. "Reversing Enantioselectivity in Capillary GC with Polar and Nonpolar Cyclodextrin Derivative Phases", D. W.
`Armstrong, W. Li and J. Pitha, Anal. Chem., 62, 214-217 (1990).
`
`102. "Evaluation of the Effect of Organic Modifier and pH on Retention and Selectivity in Reversed-Phase LC
`Separation of Alkaloids on a Cyclodextrin Bonded Phase", D. W. Armstrong, G. L. Bertrand, K. D. Ward, T. J. Ward, H.
`V. Secor and J. I. Seeman, Anal. Chem., 62, 332-338 (1990).
`
`103. "Derivatized Cyclodextrin for Normal Phase LC Separation of Enantiomers", D. W. Armstrong, A. M. Stalcup, M.
`L. Hilton, J. D. Duncan, J. Faulkner, Jr., S. C. Chang, Anal. Chem., 62, 1610-1615 (1990).
`
`104. "Polar-Liquid, Derivatized Cyclodextrin Stationary Phases for the Capillary GC Separation of Enantiomers", D. W.
`Armstrong, W. Li, C.-D. Chang and J. Pitha, Anal. Chem., 62, 914-923 (1990).
`
`105. "Acylation Effects on Chiral Recognition of Racemic Amines and Alcohols by New Polar and Nonpolar
`Cyclodextrin-Derivative GC Phases", D. W. Armstrong and H.L. Jin, J. of Chromatogr., 502, 154-159 (1990).
`
`106. "Chiral Mobile Phase Additives in Reversed-Phase TLC", J. D. Duncan, and D. W. Armstrong, J. of Planar
`Chromatogr., 3, 65-68 (1990).
`
`107. "Interactions of Chiral Molecules with an (R)-N(3,5-Dinitrobenzoyl) Phenylglycine HPLC Stationary Phase", A.
`Berthod, H. L. Jin, A. M. Stalcup and D. W. Armstrong, Chirality, 2, 38-42 (1990).
`
`108. "Cyclodextrin Chiral Stationary Phases for LC Separations of Drug Stereoisomers", A. Berthod, H. L. Jin, T. E.
`Beesley, J. D. Duncan and D. W. Armstrong, J. of Pharm. Biomed Analysis, 8, 123-130 (1990).
`
`109. "Separation of Carotenes on Cyclodextrin-Bonded Phases", A. M. Stalcup, H. L. Jin, D. W. Armstrong, P. Marzur,
`F. Derguini and K. Nakanishi, J. of Chromatogr., 499, 627-635 (1990).
`
`110. "Capillary Gas Chromatographic Separation of Enantiomers with a Stable Dialkyl-β-Cyclodextrin Derivatized
`Stationary Phase", D. W. Armstrong, W. Li, A. M. Stalcup, H. Secor, R. Izak, and J. I. Seeman, Anal. Chim. Acta, 234,
`365-381 (1990).
`
`111. "Chiral Recognition of Racemic Sugars by Polar and Nonpolar Cyclodextrin-Derivative Gas Chromatography", A.
`Berthod, W.-Y. Li, and D. W. Armstrong, Carbohydrate Research, 201, 175-184 (1990).
`
`112. "Normal Phase TLC Separation of Enantiomers Using Chiral Ion Interaction Agents", J. D. Duncan, D. W.
`Armstrong and A. M. Stalcup, J. Liq. Chromatogr., 13, 1091-1103 (1990).
`
`113. "Separation of Enantiomers Using a γ-Cyclodextrin Liquid Chromatographic Bonded Phase", A. M. Stalcup, H. L.
`Jin and D. W. Armstrong, J. Liq. Chromatogr., 13, 473-484 (1990).
`
`114. "(S)-2-Hydroxypropyl β-CD: A New Chiral Stationary Phase for Reversed-Phase Liquid Chromatography", A. M.
`Stalcup, S. C. Chang, D. W. Armstrong, and J. Pitha, J. of Chromatogr., 513, 181-194 (1990).
`
`115. "Relevance of Enantiomeric Separations in Food and Beverage Analyses", D. W. Armstrong and C. D. Chang, J.
`Ag. Food Chem., 38, 1674-1677 (1990).
`
`116. "2,6-Di-O-pentyl-3-O-Trifluoroacetyl Cyclodextrin Liquid Stationary Phases for Capillary Gas Chromatographic
`Separation of Enantiomers", W.Y. Li, H. L. Jin and D. W. Armstrong, J. Chromatogr., 509, 303-324 (1990).
`
`
`10
`
`LOWER DRUG PRICES FOR CONSUMERS, LLC
`Exhibit 1051-10
`IPR2016-00379
`
`

`
`117. "Direct Measurement of Octanol-Water Partition Coefficients Using CPC with a Back-Flushing Technique”, R. A.
`Menges, G. L. Bertrand and D. W. Armstrong, J. Liq. Chromatogr., 13, 3061-3077 (1990).
`
`118. "Use of CPC and Proteins in the Preparative Separation of Amino Acid Enantiomers", D. W. Armstrong, R. A.
`Menges and I. W. Wainer, J. Liq. Chro

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